diff --git a/DESCRIPTION b/DESCRIPTION index 996a098e..052238a6 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -24,15 +24,15 @@ URL: https://github.com/insightsengineering/scda.test/ BugReports: https://github.com/insightsengineering/scda.test/issues Depends: formatters (>= 0.5.12), - junco (>= 0.1.6.9001), + junco (>= 0.1.7), R (>= 4.2), rlistings (>= 0.2.13), - rtables (>= 0.6.16), - tern (>= 0.9.10) + rtables (>= 0.6.17), + tern (>= 0.9.13) Imports: pharmaverseadam (>= 1.3.0), - pharmaverseadamjnj (>= 0.0.5), - pharmaversesdtmjnj (>= 0.0.4), + pharmaverseadamjnj (>= 0.0.8), + pharmaversesdtmjnj (>= 0.0.6), random.cdisc.data (>= 0.3.16) Suggests: broom, @@ -52,9 +52,6 @@ Suggests: VignetteBuilder: knitr Remotes: - johnsonandjohnson/junco@dev, - johnsonandjohnson/pharmaverseadamjnj@main, - johnsonandjohnson/pharmaversesdtmjnj@main, pharmaverse/formatters@main, pharmaverse/pharmaverseadam@main, pharmaverse/rlistings@main, diff --git a/tests/testthat/_snaps/lirada01/lirada01.rtf b/tests/testthat/_snaps/lirada01/lirada01.rtf new file mode 100644 index 00000000..0a408135 --- /dev/null +++ b/tests/testthat/_snaps/lirada01/lirada01.rtf @@ -0,0 +1,2292 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx950 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3797 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6464 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7503 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8724 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9311 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10125 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11345 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LIRADA01:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx950 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3797 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6464 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7503 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8724 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9311 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10125 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11345 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Visit \cell +\pard\intbl\qc\fs16 \keepn\trhdr [Injection / Infusion / Dose] Given? \cell +\pard\intbl\qc\fs16 \keepn\trhdr [Injection Site / Infusion-related] Reaction \cell +\pard\intbl\qc\fs16 \keepn\trhdr Serious \cell +\pard\intbl\qc\fs16 \keepn\trhdr Maximum Severity \cell +\pard\intbl\qc\fs16 \keepn\trhdr Matrix Active Study Agent Conc. (mcg/mL) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Antibodies To Active Study Agent Status/Titer \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.69 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Moderate \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Moderate \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.23 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Moderate \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1442 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.86 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.01 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-702-1082 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Moderate \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Moderate \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Moderate \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1086 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.79 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.16 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1279 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.94 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.78 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1009 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.92 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.98 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.85 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.69 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.12 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.82 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.01 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 0.95 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.72 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1292 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.98 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.78 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1431 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.25 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-706-1384 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Moderate \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Moderate \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.94 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Moderate \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.76 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.9 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1348 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.92 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Mild \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.97 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1020 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.93 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.11 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1102 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.86 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.08 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1285 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.79 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.09 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1424 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.84 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.96 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1045 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.08 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1270 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.68 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.01 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1358 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.88 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.02 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.93 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1385 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.01 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.06 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1043 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.85 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1195 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.82 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1425 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.05 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1030 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.14 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1103 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.13 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1079 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.17 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.74 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx950 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3797 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6464 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7503 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8724 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9311 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10125 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11345 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1170 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.05 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx950 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3797 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6464 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7503 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8724 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9311 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10125 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11345 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx950 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3797 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6464 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7503 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8724 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9311 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10125 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11345 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} +\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} +} \ No newline at end of file diff --git a/tests/testthat/_snaps/lirada02/lirada02.rtf b/tests/testthat/_snaps/lirada02/lirada02.rtf new file mode 100644 index 00000000..427c79b8 --- /dev/null +++ b/tests/testthat/_snaps/lirada02/lirada02.rtf @@ -0,0 +1,1876 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2630 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5259 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6997 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10161 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11364 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LIRADA02:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2630 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5259 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6997 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10161 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11364 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Visit \cell +\pard\intbl\qc\fs16 \keepn\trhdr Reason for Discontinuation \cell +\pard\intbl\qc\fs16 \keepn\trhdr Last Scheduled Study Treatment \cell +\pard\intbl\qc\fs16 \keepn\trhdr Matrix Active Study Agent Conc. (mcg/mL) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Antibodies To Active Study Agent Status/Titer \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.87 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.7 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.08 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.79 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.26 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.72 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.01 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 0.98 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.02 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.23 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Death \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Death \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.01 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Death \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.11 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.02 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.72 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.31 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.16 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 0.96 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 0.98 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1403 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.05 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1009 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.92 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.98 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.81 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.96 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.85 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.69 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.23 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.31 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.82 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.07 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.68 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.31 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.01 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 0.95 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.72 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1382 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1393 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.26 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.04 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.06 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1019 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1032 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.76 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.74 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1213 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.75 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.15 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.9 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Death \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 3.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Death \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.07 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Death \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.17 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1372 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.95 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.92 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1428 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Protocol Violation \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1081 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.82 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 2.05 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1102 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.86 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2630 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6997 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10161 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11364 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 54 \cell +\pard\intbl\qc\fs16 1.47 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2630 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5259 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6997 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10161 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11364 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10161 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11364 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} +\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} +} \ No newline at end of file diff --git a/tests/testthat/_snaps/lirada03/lirada03.rtf b/tests/testthat/_snaps/lirada03/lirada03.rtf new file mode 100644 index 00000000..16012d70 --- /dev/null +++ b/tests/testthat/_snaps/lirada03/lirada03.rtf @@ -0,0 +1,1461 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2946 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5845 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8560 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11321 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LIRADA03:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2946 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5845 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8560 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11321 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Visit \cell +\pard\intbl\qc\fs16 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs16 \keepn\trhdr Matrix Active Study Agent +Conc. (mcg/mL) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 28.04 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1097 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 5 Min Post-dose \cell +\pard\intbl\qc\fs16 0.09949 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 30 Min Post-dose \cell +\pard\intbl\qc\fs16 0.5413 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1h Post-dose \cell +\pard\intbl\qc\fs16 0.9261 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.5h Post-dose \cell +\pard\intbl\qc\fs16 1.2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2h Post-dose \cell +\pard\intbl\qc\fs16 1.394 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 27.54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4h Post-dose \cell +\pard\intbl\qc\fs16 1.75 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6h Post-dose \cell +\pard\intbl\qc\fs16 1.84 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.864 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 23.44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12h Post-dose \cell +\pard\intbl\qc\fs16 0.5717 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 16h Post-dose \cell +\pard\intbl\qc\fs16 0.1746 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 15.24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 0.01629 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 24h Post-dose \cell +\pard\intbl\qc\fs16 0.01629 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 36h Post-dose \cell +\pard\intbl\qc\fs16 0.005 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 24-48h Post-dose \cell +\pard\intbl\qc\fs16 0.005 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 0.005 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 48h Post-dose \cell +\pard\intbl\qc\fs16 0.005 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 28.88 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 24.93 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 1.5h Post-dose \cell +\pard\intbl\qc\fs16 1.184 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2h Post-dose \cell +\pard\intbl\qc\fs16 1.374 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 26.99 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4h Post-dose \cell +\pard\intbl\qc\fs16 1.717 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6h Post-dose \cell +\pard\intbl\qc\fs16 1.803 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.824 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 22.83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 14.51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 25.55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 21.22 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 12.55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 1h Post-dose \cell +\pard\intbl\qc\fs16 0.9845 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.5h Post-dose \cell +\pard\intbl\qc\fs16 1.266 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2h Post-dose \cell +\pard\intbl\qc\fs16 1.462 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 25.5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4h Post-dose \cell +\pard\intbl\qc\fs16 1.806 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6h Post-dose \cell +\pard\intbl\qc\fs16 1.886 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.905 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 21.16 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 12.47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 28.8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 24.84 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 28.28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 1h Post-dose \cell +\pard\intbl\qc\fs16 0.9216 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.5h Post-dose \cell +\pard\intbl\qc\fs16 1.199 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2h Post-dose \cell +\pard\intbl\qc\fs16 1.399 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 28.86 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4h Post-dose \cell +\pard\intbl\qc\fs16 1.774 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6h Post-dose \cell +\pard\intbl\qc\fs16 1.874 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.901 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 24.91 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 17.02 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 24-48h Post-dose \cell +\pard\intbl\qc\fs16 1.217 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 25.63 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 1h Post-dose \cell +\pard\intbl\qc\fs16 1.002 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.5h Post-dose \cell +\pard\intbl\qc\fs16 1.285 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2h Post-dose \cell +\pard\intbl\qc\fs16 1.48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 24.65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4h Post-dose \cell +\pard\intbl\qc\fs16 1.815 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6h Post-dose \cell +\pard\intbl\qc\fs16 1.891 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.908 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 20.19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 11.29 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 26.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 21.83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 13.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 27.52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 23.42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 15.22 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 25.73 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-702-1082 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 26.71 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 22.52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 14.13 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1086 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 25.01 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 20.6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 11.79 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 1.5h Post-dose \cell +\pard\intbl\qc\fs16 1.143 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2h Post-dose \cell +\pard\intbl\qc\fs16 1.331 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 28.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4h Post-dose \cell +\pard\intbl\qc\fs16 1.68 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6h Post-dose \cell +\pard\intbl\qc\fs16 1.772 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.796 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 24.29 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 16.27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 30 Min Post-dose \cell +\pard\intbl\qc\fs16 0.5297 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1h Post-dose \cell +\pard\intbl\qc\fs16 0.9008 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1.5h Post-dose \cell +\pard\intbl\qc\fs16 1.161 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2h Post-dose \cell +\pard\intbl\qc\fs16 1.343 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0-6h Post-dose \cell +\pard\intbl\qc\fs16 26.09 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4h Post-dose \cell +\pard\intbl\qc\fs16 1.667 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6h Post-dose \cell +\pard\intbl\qc\fs16 1.745 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.764 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6-12h Post-dose \cell +\pard\intbl\qc\fs16 21.82 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12h Post-dose \cell +\pard\intbl\qc\fs16 0.5142 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12-24h Post-dose \cell +\pard\intbl\qc\fs16 13.28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 1.5h Post-dose \cell +\pard\intbl\qc\fs16 1.237 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2946 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5845 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8560 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11321 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2h Post-dose \cell +\pard\intbl\qc\fs16 1.432 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2946 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5845 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8560 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11321 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2946 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5845 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8560 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11321 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} +\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} +} \ No newline at end of file diff --git a/tests/testthat/_snaps/lirada04/lirada04.rtf b/tests/testthat/_snaps/lirada04/lirada04.rtf new file mode 100644 index 00000000..956d40e4 --- /dev/null +++ b/tests/testthat/_snaps/lirada04/lirada04.rtf @@ -0,0 +1,1044 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5725 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11360 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LIRADA04:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5725 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11360 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Baseline Titer \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1097 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1442 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-702-1082 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1086 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1279 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1379 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1403 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1009 \cell +\pard\intbl\qc\fs16 320 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1135 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1292 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1382 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1393 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1431 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-706-1384 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1019 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1032 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1084 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1213 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 320 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1348 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1353 \cell +\pard\intbl\qc\fs16 320 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1372 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1428 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1007 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1020 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1081 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1102 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1285 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1326 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1329 \cell +\pard\intbl\qc\fs16 320 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1424 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1002 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1045 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1053 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1154 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1166 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1235 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1270 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1300 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1358 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1385 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-711-1143 \cell +\pard\intbl\qc\fs16 320 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-711-1433 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1043 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1073 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1448 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1068 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1195 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1425 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1085 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1107 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1405 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1030 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1063 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1094 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1103 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1151 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1157 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1167 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1298 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1311 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1004 \cell +\pard\intbl\qc\fs16 320 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1446 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1066 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1079 \cell +\pard\intbl\qc\fs16 80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1170 \cell +\pard\intbl\qc\fs16 640 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1250 \cell +\pard\intbl\qc\fs16 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1254 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1028 \cell +\pard\intbl\qc\fs16 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1034 \cell +\pard\intbl\qc\fs16 1280 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1133 \cell +\pard\intbl\qc\fs16 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5725 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11360 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1146 \cell +\pard\intbl\qc\fs16 160 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5725 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11360 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5725 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11360 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} +\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} +} \ No newline at end of file diff --git a/tests/testthat/_snaps/lirada05/lirada05.rtf b/tests/testthat/_snaps/lirada05/lirada05.rtf new file mode 100644 index 00000000..e94c926e --- /dev/null +++ b/tests/testthat/_snaps/lirada05/lirada05.rtf @@ -0,0 +1,2084 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1739 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3432 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4546 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5482 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8111 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10785 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12077 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LIRADA05:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1739 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3432 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4546 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5482 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8111 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10785 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12077 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject Status\super a\nosupersub for Treatment-Emergent ADA \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject Status for NAb \cell +\pard\intbl\qc\fs16 \keepn\trhdr Visit \cell +\pard\intbl\qc\fs16 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs16 \keepn\trhdr Antibody to active study agent Status/Titer \cell +\pard\intbl\qc\fs16 \keepn\trhdr Sample Status for NAb \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 POSITIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 2.06 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 2.06 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 2.06 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.71 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.71 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.71 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.54 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.54 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.54 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1097 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 2.34 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 2.34 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 2.34 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.58 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.58 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.58 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.33 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.33 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.33 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 2.87 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 2.87 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 2.87 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.7 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.7 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.7 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.08 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.08 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.08 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 POSITIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.79 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.79 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.79 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.47 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.47 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.47 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 2.1 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 2.1 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 2.1 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 2.61 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 2.61 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 2.61 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.45 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.45 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.45 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 2.26 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 2.26 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 2.26 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 POSITIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.21 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.21 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.21 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 2.59 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 2.59 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 2.59 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 POSITIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.33 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.33 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.33 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.03 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.03 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.03 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 2.44 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 2.44 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 2.44 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 POSITIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.46 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.46 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.46 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.48 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.48 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.48 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.72 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.72 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.72 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 POSITIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.83 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.83 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.83 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 2.01 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 2.01 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 0.98 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 0.98 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 POSITIVE \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.49 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.49 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.49 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.41 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.41 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.41 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.69 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.69 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.69 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.96 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.96 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.36 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.36 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 2.06 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 2.06 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 3 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 2.06 \cell +\pard\intbl\qc\fs16 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 NEGATIVE \cell +\pard\intbl\qc\fs16 POSITIVE \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.35 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.35 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.35 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 1.02 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 Dose \cell +\pard\intbl\qc\fs16 1.02 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1739 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3432 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4546 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5482 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10785 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Day 2 \cell +\pard\intbl\qc\fs16 8h Post-dose \cell +\pard\intbl\qc\fs16 1.02 \cell +\pard\intbl\qc\fs16 1 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1739 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3432 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4546 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5482 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8111 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10785 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12077 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1739 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3432 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5482 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10785 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} +\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} +} \ No newline at end of file diff --git a/tests/testthat/_snaps/lpk01/lpk01.rtf b/tests/testthat/_snaps/lpk01/lpk01.rtf new file mode 100644 index 00000000..3af49f28 --- /dev/null +++ b/tests/testthat/_snaps/lpk01/lpk01.rtf @@ -0,0 +1,1876 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx946 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2072 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4730 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8152 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10855 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11936 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LPK01:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx946 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2072 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4730 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8152 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10855 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11936 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Visit \cell +\pard\intbl\qc\fs16 \keepn\trhdr Sample Date / Time \cell +\pard\intbl\qc\fs16 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs16 \keepn\trhdr Matrix Active Study Agent Conc. (\u181?g/mL) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Reason for Exclusion \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx946 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2072 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4730 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8152 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10855 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11936 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 Day 1 \cell +\pard\intbl\qc\fs16 17MAR2014 / 23:30 \cell +\pard\intbl\qc\fs16 Pre-dose \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 285 N CS \cell -\pard\intbl\qc\fs16 247 \cell +\pard\intbl\qc\fs16 518 \cell +\pard\intbl\qc\fs16 493 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 499 N CS \cell -\pard\intbl\qc\fs16 461 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 456 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >200 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 343 N CS \cell -\pard\intbl\qc\fs16 305 \cell -\pard\intbl\qc\fs16 >100 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 309 N CS \cell -\pard\intbl\qc\fs16 271 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 197 \cell +\pard\intbl\qc\fs16 -259 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 458 N CS \cell -\pard\intbl\qc\fs16 420 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 301 \cell +\pard\intbl\qc\fs16 -155 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 19 N CS \cell -\pard\intbl\qc\fs16 -19 \cell +\pard\intbl\qc\fs16 417 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >100 \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 194 N CS \cell -\pard\intbl\qc\fs16 156 \cell +\pard\intbl\qc\fs16 568 \cell +\pard\intbl\qc\fs16 151 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 370 H CS \cell +\pard\intbl\qc\fs16 544 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 363 H CS \cell -\pard\intbl\qc\fs16 -7 \cell +\pard\intbl\qc\fs16 222 \cell +\pard\intbl\qc\fs16 -322 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell +\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 98 H CS \cell -\pard\intbl\qc\fs16 -272 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 423 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 196 N CS \cell -\pard\intbl\qc\fs16 -174 \cell +\pard\intbl\qc\fs16 >100 \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 333 H CS \cell -\pard\intbl\qc\fs16 -37 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 -418 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 149 H CS \cell -\pard\intbl\qc\fs16 -221 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 127 \cell +\pard\intbl\qc\fs16 -296 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 201 H CS \cell -\pard\intbl\qc\fs16 -169 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 48 \cell +\pard\intbl\qc\fs16 -375 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 530 H CS \cell -\pard\intbl\qc\fs16 160 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 475 \cell +\pard\intbl\qc\fs16 52 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Month 24 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 596 H CS \cell -\pard\intbl\qc\fs16 226 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 77 / F / White \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 01JUL2014 / 04:00 (1) \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 257 N CS \cell +\pard\intbl\qc\fs16 105 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <120 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >100 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 15JUL2014 / 04:00 (15) \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 176 N CS \cell -\pard\intbl\qc\fs16 -81 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 61 \cell +\pard\intbl\qc\fs16 -44 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29JUL2014 / 04:00 (29) \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 385 N CS \cell -\pard\intbl\qc\fs16 128 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 151 \cell +\pard\intbl\qc\fs16 46 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11AUG2014 / 04:00 (42) \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell \pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 140 N CS \cell -\pard\intbl\qc\fs16 -117 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 92 \cell +\pard\intbl\qc\fs16 -13 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26AUG2014 / 04:00 (57) \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell \pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 23 N CS \cell -\pard\intbl\qc\fs16 -234 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 351 \cell +\pard\intbl\qc\fs16 246 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 79 / Female / Not reported \cell +\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 25 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <50 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25SEP2014 / 04:00 (87) \cell -\pard\intbl\qc\fs16 Month 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 465 N CS \cell -\pard\intbl\qc\fs16 208 \cell -\pard\intbl\qc\fs16 >100 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 21OCT2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 129 N CS \cell -\pard\intbl\qc\fs16 -128 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 45 \cell +\pard\intbl\qc\fs16 20 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 18NOV2014 / 05:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 164 N CS \cell -\pard\intbl\qc\fs16 -93 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 390 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17DEC2014 / 05:00 (170) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 587 N CS \cell -\pard\intbl\qc\fs16 330 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 280 \cell +\pard\intbl\qc\fs16 -110 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 01JUL2014 / 04:00 (1) \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs16 15FEB2013 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 472 H CS \cell +\pard\intbl\qc\fs16 583 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >100 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >200 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 15JUL2014 / 04:00 (15) \cell +\pard\intbl\qc\fs16 02MAR2013 / 06:00 (16) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 68 H CS \cell -\pard\intbl\qc\fs16 -404 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 201 \cell +\pard\intbl\qc\fs16 -382 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29JUL2014 / 04:00 (29) \cell +\pard\intbl\qc\fs16 16MAR2013 / 06:00 (30) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 168 H CS \cell -\pard\intbl\qc\fs16 -304 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 347 \cell +\pard\intbl\qc\fs16 -236 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11AUG2014 / 04:00 (42) \cell +\pard\intbl\qc\fs16 25MAR2013 / 06:00 (39) \cell \pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 254 H CS \cell -\pard\intbl\qc\fs16 -218 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 548 \cell +\pard\intbl\qc\fs16 -35 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26AUG2014 / 04:00 (57) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 15FEB2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 513 H CS \cell -\pard\intbl\qc\fs16 41 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 258 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25SEP2014 / 04:00 (87) \cell -\pard\intbl\qc\fs16 Month 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 273 H CS \cell -\pard\intbl\qc\fs16 -199 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 21OCT2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 02MAR2013 / 06:00 (16) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 137 H CS \cell -\pard\intbl\qc\fs16 -335 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 320 \cell +\pard\intbl\qc\fs16 62 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 18NOV2014 / 05:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 16MAR2013 / 06:00 (30) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 512 H CS \cell -\pard\intbl\qc\fs16 40 \cell +\pard\intbl\qc\fs16 579 \cell +\pard\intbl\qc\fs16 321 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17DEC2014 / 05:00 (170) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 25MAR2013 / 06:00 (39) \cell +\pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 579 H CS \cell -\pard\intbl\qc\fs16 107 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 180 \cell +\pard\intbl\qc\fs16 -78 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1146 \cell -\pard\intbl\qc\fs16 75 / F / Unknown \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell \pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 20MAY2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 22JUL2012 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 199 N CS \cell +\pard\intbl\qc\fs16 476 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 03JUN2013 / 04:00 (15) \cell +\pard\intbl\qc\fs16 07AUG2012 / 06:00 (17) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 236 N CS \cell -\pard\intbl\qc\fs16 37 \cell +\pard\intbl\qc\fs16 557 \cell +\pard\intbl\qc\fs16 81 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 16JUN2013 / 04:00 (28) \cell +\pard\intbl\qc\fs16 21AUG2012 / 06:00 (31) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 257 N CS \cell -\pard\intbl\qc\fs16 58 \cell +\pard\intbl\qc\fs16 523 \cell +\pard\intbl\qc\fs16 47 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 30JUN2013 / 04:00 (42) \cell +\pard\intbl\qc\fs16 04SEP2012 / 06:00 (45) \cell \pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 379 N CS \cell -\pard\intbl\qc\fs16 180 \cell +\pard\intbl\qc\fs16 311 \cell +\pard\intbl\qc\fs16 -165 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 20MAY2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 52 H CS \cell -\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23SEP2012 / 06:00 (64) \cell +\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 -476 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 03JUN2013 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell +\pard\intbl\qc\fs16 14OCT2012 / 06:00 (85) \cell +\pard\intbl\qc\fs16 Month 12 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 499 H CS \cell -\pard\intbl\qc\fs16 447 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 497 \cell +\pard\intbl\qc\fs16 21 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 16JUN2013 / 04:00 (28) \cell -\pard\intbl\qc\fs16 Month 3 \cell +\pard\intbl\qc\fs16 15NOV2012 / 06:00 (117) \cell +\pard\intbl\qc\fs16 Month 15 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 126 H CS \cell -\pard\intbl\qc\fs16 74 \cell +\pard\intbl\qc\fs16 51 \cell +\pard\intbl\qc\fs16 -425 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 30JUN2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (145) \cell +\pard\intbl\qc\fs16 Month 18 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 142 H CS \cell -\pard\intbl\qc\fs16 90 \cell +\pard\intbl\qc\fs16 518 \cell +\pard\intbl\qc\fs16 42 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 11JAN2013 / 06:00 (174) \cell +\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 196 \cell +\pard\intbl\qc\fs16 -280 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1148 \cell -\pard\intbl\qc\fs16 57 / M / Not reported \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 23AUG2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 22JUL2012 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 420 N CS \cell +\pard\intbl\qc\fs16 340 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >200 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >100 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 05SEP2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 07AUG2012 / 06:00 (17) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 443 N CS \cell -\pard\intbl\qc\fs16 23 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 196 \cell +\pard\intbl\qc\fs16 -144 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 19SEP2013 / 04:00 (28) \cell +\pard\intbl\qc\fs16 21AUG2012 / 06:00 (31) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 28 N CS \cell -\pard\intbl\qc\fs16 -392 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 288 \cell +\pard\intbl\qc\fs16 -52 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 03OCT2013 / 04:00 (42) \cell +\pard\intbl\qc\fs16 04SEP2012 / 06:00 (45) \cell \pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 240 N CS \cell -\pard\intbl\qc\fs16 -180 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 58 \cell +\pard\intbl\qc\fs16 -282 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 18OCT2013 / 04:00 (57) \cell +\pard\intbl\qc\fs16 23SEP2012 / 06:00 (64) \cell \pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 41 N CS \cell -\pard\intbl\qc\fs16 -379 \cell +\pard\intbl\qc\fs16 122 \cell +\pard\intbl\qc\fs16 -218 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17NOV2013 / 05:00 (87) \cell +\pard\intbl\qc\fs16 14OCT2012 / 06:00 (85) \cell \pard\intbl\qc\fs16 Month 12 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 43 N CS \cell -\pard\intbl\qc\fs16 -377 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 224 \cell +\pard\intbl\qc\fs16 -116 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 13DEC2013 / 05:00 (113) \cell +\pard\intbl\qc\fs16 15NOV2012 / 06:00 (117) \cell \pard\intbl\qc\fs16 Month 15 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 223 N CS \cell -\pard\intbl\qc\fs16 -197 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 584 \cell +\pard\intbl\qc\fs16 244 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10JAN2014 / 05:00 (141) \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (145) \cell \pard\intbl\qc\fs16 Month 18 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 7 N CS \cell -\pard\intbl\qc\fs16 -413 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 207 \cell +\pard\intbl\qc\fs16 -133 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 08FEB2014 / 05:00 (170) \cell +\pard\intbl\qc\fs16 11JAN2013 / 06:00 (174) \cell \pard\intbl\qc\fs16 Month 24 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 550 N CS \cell -\pard\intbl\qc\fs16 130 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 558 \cell +\pard\intbl\qc\fs16 218 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 23AUG2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell +\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs16 15NOV2012 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 484 H CS \cell +\pard\intbl\qc\fs16 423 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >100 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >200 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 05SEP2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 28NOV2012 / 06:00 (14) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 217 H CS \cell -\pard\intbl\qc\fs16 -267 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 260 \cell +\pard\intbl\qc\fs16 -163 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 19SEP2013 / 04:00 (28) \cell +\pard\intbl\qc\fs16 11DEC2012 / 06:00 (27) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 321 H CS \cell -\pard\intbl\qc\fs16 -163 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 466 \cell +\pard\intbl\qc\fs16 43 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 03OCT2013 / 04:00 (42) \cell +\pard\intbl\qc\fs16 25DEC2012 / 06:00 (41) \cell \pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 296 H CS \cell -\pard\intbl\qc\fs16 -188 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 491 \cell +\pard\intbl\qc\fs16 68 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 18OCT2013 / 04:00 (57) \cell +\pard\intbl\qc\fs16 08JAN2013 / 06:00 (55) \cell \pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 360 H CS \cell -\pard\intbl\qc\fs16 -124 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 582 \cell +\pard\intbl\qc\fs16 159 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17NOV2013 / 05:00 (87) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 15NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 89 H CS \cell -\pard\intbl\qc\fs16 -395 \cell +\pard\intbl\qc\fs16 142 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 13DEC2013 / 05:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 28NOV2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 188 H CS \cell -\pard\intbl\qc\fs16 -296 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 -141 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10JAN2014 / 05:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 11DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 569 H CS \cell -\pard\intbl\qc\fs16 85 \cell +\pard\intbl\qc\fs16 424 \cell +\pard\intbl\qc\fs16 282 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 08FEB2014 / 05:00 (170) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 25DEC2012 / 06:00 (41) \cell +\pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 440 H CS \cell -\pard\intbl\qc\fs16 -44 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 90 \cell +\pard\intbl\qc\fs16 -52 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1239 \cell -\pard\intbl\qc\fs16 56 / M / White \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 08JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 119 \cell +\pard\intbl\qc\fs16 -23 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 68 / Male / Unknown \cell \pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 11JAN2014 / 05:00 (1) \cell +\pard\intbl\qc\fs16 22MAY2014 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 379 N CS \cell +\pard\intbl\qc\fs16 526 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25JAN2014 / 05:00 (15) \cell +\pard\intbl\qc\fs16 05JUN2014 / 06:00 (15) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 407 N CS \cell -\pard\intbl\qc\fs16 28 \cell +\pard\intbl\qc\fs16 347 \cell +\pard\intbl\qc\fs16 -179 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 08FEB2014 / 05:00 (29) \cell +\pard\intbl\qc\fs16 19JUN2014 / 06:00 (29) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 134 N CS \cell -\pard\intbl\qc\fs16 -245 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 39 \cell +\pard\intbl\qc\fs16 -487 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 19FEB2014 / 05:00 (40) \cell +\pard\intbl\qc\fs16 03JUL2014 / 06:00 (43) \cell \pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 194 N CS \cell -\pard\intbl\qc\fs16 -185 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 74 \cell +\pard\intbl\qc\fs16 -452 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06MAR2014 / 05:00 (55) \cell +\pard\intbl\qc\fs16 22JUL2014 / 06:00 (62) \cell \pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 206 N CS \cell -\pard\intbl\qc\fs16 -173 \cell +\pard\intbl\qc\fs16 146 \cell +\pard\intbl\qc\fs16 -380 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02APR2014 / 04:00 (82) \cell +\pard\intbl\qc\fs16 15AUG2014 / 06:00 (86) \cell \pard\intbl\qc\fs16 Month 12 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 474 N CS \cell -\pard\intbl\qc\fs16 95 \cell +\pard\intbl\qc\fs16 296 \cell +\pard\intbl\qc\fs16 -230 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02MAY2014 / 04:00 (112) \cell +\pard\intbl\qc\fs16 11SEP2014 / 06:00 (113) \cell \pard\intbl\qc\fs16 Month 15 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 279 N CS \cell -\pard\intbl\qc\fs16 -100 \cell +\pard\intbl\qc\fs16 121 \cell +\pard\intbl\qc\fs16 -405 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 28MAY2014 / 04:00 (138) \cell +\pard\intbl\qc\fs16 09OCT2014 / 06:00 (141) \cell \pard\intbl\qc\fs16 Month 18 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 598 N CS \cell -\pard\intbl\qc\fs16 219 \cell +\pard\intbl\qc\fs16 261 \cell +\pard\intbl\qc\fs16 -265 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27JUN2014 / 04:00 (168) \cell +\pard\intbl\qc\fs16 06NOV2014 / 06:00 (169) \cell \pard\intbl\qc\fs16 Month 24 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 45 N CS \cell -\pard\intbl\qc\fs16 -334 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 208 \cell +\pard\intbl\qc\fs16 -318 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 11JAN2014 / 05:00 (1) \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 22MAY2014 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 445 N CS \cell +\pard\intbl\qc\fs16 336 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25JAN2014 / 05:00 (15) \cell +\pard\intbl\qc\fs16 05JUN2014 / 06:00 (15) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 358 H CS \cell -\pard\intbl\qc\fs16 -87 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 162 \cell +\pard\intbl\qc\fs16 -174 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 08FEB2014 / 05:00 (29) \cell +\pard\intbl\qc\fs16 19JUN2014 / 06:00 (29) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 430 H CS \cell -\pard\intbl\qc\fs16 -15 \cell +\pard\intbl\qc\fs16 326 \cell +\pard\intbl\qc\fs16 -10 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 19FEB2014 / 05:00 (40) \cell +\pard\intbl\qc\fs16 03JUL2014 / 06:00 (43) \cell \pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 582 H CS \cell -\pard\intbl\qc\fs16 137 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 52 \cell +\pard\intbl\qc\fs16 -284 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06MAR2014 / 05:00 (55) \cell +\pard\intbl\qc\fs16 22JUL2014 / 06:00 (62) \cell \pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 570 H CS \cell -\pard\intbl\qc\fs16 125 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 143 \cell +\pard\intbl\qc\fs16 -193 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02APR2014 / 04:00 (82) \cell +\pard\intbl\qc\fs16 15AUG2014 / 06:00 (86) \cell \pard\intbl\qc\fs16 Month 12 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 40 H CS \cell -\pard\intbl\qc\fs16 -405 \cell +\pard\intbl\qc\fs16 168 \cell +\pard\intbl\qc\fs16 -168 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02MAY2014 / 04:00 (112) \cell +\pard\intbl\qc\fs16 11SEP2014 / 06:00 (113) \cell \pard\intbl\qc\fs16 Month 15 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 343 H CS \cell -\pard\intbl\qc\fs16 -102 \cell +\pard\intbl\qc\fs16 279 \cell +\pard\intbl\qc\fs16 -57 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 28MAY2014 / 04:00 (138) \cell +\pard\intbl\qc\fs16 09OCT2014 / 06:00 (141) \cell \pard\intbl\qc\fs16 Month 18 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 142 H CS \cell -\pard\intbl\qc\fs16 -303 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 210 \cell +\pard\intbl\qc\fs16 -126 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27JUN2014 / 04:00 (168) \cell +\pard\intbl\qc\fs16 06NOV2014 / 06:00 (169) \cell \pard\intbl\qc\fs16 Month 24 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0 H CS \cell -\pard\intbl\qc\fs16 -445 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 119 \cell +\pard\intbl\qc\fs16 -217 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1275 \cell -\pard\intbl\qc\fs16 61 / M / White \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 79 / Male / Asian \cell \pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 07FEB2014 / 05:00 (1) \cell +\pard\intbl\qc\fs16 02OCT2012 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 286 N CS \cell +\pard\intbl\qc\fs16 423 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 22FEB2014 / 05:00 (16) \cell +\pard\intbl\qc\fs16 16OCT2012 / 06:00 (15) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 50 N CS \cell -\pard\intbl\qc\fs16 -236 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 378 \cell +\pard\intbl\qc\fs16 -45 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 07MAR2014 / 05:00 (29) \cell +\pard\intbl\qc\fs16 30OCT2012 / 06:00 (29) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 528 N CS \cell -\pard\intbl\qc\fs16 242 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 -418 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 22MAR2014 / 05:00 (44) \cell +\pard\intbl\qc\fs16 13NOV2012 / 06:00 (43) \cell \pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 456 N CS \cell -\pard\intbl\qc\fs16 170 \cell +\pard\intbl\qc\fs16 516 \cell +\pard\intbl\qc\fs16 93 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 05APR2014 / 04:00 (58) \cell +\pard\intbl\qc\fs16 25NOV2012 / 06:00 (55) \cell \pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 433 N CS \cell -\pard\intbl\qc\fs16 147 \cell +\pard\intbl\qc\fs16 488 \cell +\pard\intbl\qc\fs16 65 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 03MAY2014 / 04:00 (86) \cell +\pard\intbl\qc\fs16 25DEC2012 / 06:00 (85) \cell \pard\intbl\qc\fs16 Month 12 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 328 N CS \cell -\pard\intbl\qc\fs16 42 \cell +\pard\intbl\qc\fs16 488 \cell +\pard\intbl\qc\fs16 65 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JUN2014 / 04:00 (128) \cell +\pard\intbl\qc\fs16 22JAN2013 / 06:00 (113) \cell \pard\intbl\qc\fs16 Month 15 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 317 N CS \cell -\pard\intbl\qc\fs16 31 \cell +\pard\intbl\qc\fs16 356 \cell +\pard\intbl\qc\fs16 -67 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 19FEB2013 / 06:00 (141) \cell +\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 175 \cell +\pard\intbl\qc\fs16 -248 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 19MAR2013 / 06:00 (169) \cell +\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 187 \cell +\pard\intbl\qc\fs16 -236 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 07FEB2014 / 05:00 (1) \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 02OCT2012 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 357 H CS \cell +\pard\intbl\qc\fs16 379 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 22FEB2014 / 05:00 (16) \cell +\pard\intbl\qc\fs16 16OCT2012 / 06:00 (15) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 538 H CS \cell -\pard\intbl\qc\fs16 181 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 38 \cell +\pard\intbl\qc\fs16 -341 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 07MAR2014 / 05:00 (29) \cell +\pard\intbl\qc\fs16 30OCT2012 / 06:00 (29) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 13 H CS \cell -\pard\intbl\qc\fs16 -344 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 307 \cell +\pard\intbl\qc\fs16 -72 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 22MAR2014 / 05:00 (44) \cell +\pard\intbl\qc\fs16 13NOV2012 / 06:00 (43) \cell \pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 587 H CS \cell -\pard\intbl\qc\fs16 230 \cell +\pard\intbl\qc\fs16 525 \cell +\pard\intbl\qc\fs16 146 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 05APR2014 / 04:00 (58) \cell +\pard\intbl\qc\fs16 25NOV2012 / 06:00 (55) \cell \pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 503 H CS \cell -\pard\intbl\qc\fs16 146 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 28 \cell +\pard\intbl\qc\fs16 -351 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 03MAY2014 / 04:00 (86) \cell +\pard\intbl\qc\fs16 25DEC2012 / 06:00 (85) \cell \pard\intbl\qc\fs16 Month 12 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 256 H CS \cell -\pard\intbl\qc\fs16 -101 \cell +\pard\intbl\qc\fs16 291 \cell +\pard\intbl\qc\fs16 -88 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JUN2014 / 04:00 (128) \cell +\pard\intbl\qc\fs16 22JAN2013 / 06:00 (113) \cell \pard\intbl\qc\fs16 Month 15 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 591 H CS \cell -\pard\intbl\qc\fs16 234 \cell +\pard\intbl\qc\fs16 223 \cell +\pard\intbl\qc\fs16 -156 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1287 \cell -\pard\intbl\qc\fs16 56 / F / Multiple \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 25JAN2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 171 N CS \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 19FEB2013 / 06:00 (141) \cell +\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 314 \cell +\pard\intbl\qc\fs16 -65 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11FEB2014 / 05:00 (18) \cell -\pard\intbl\qc\fs16 Month 1 \cell +\pard\intbl\qc\fs16 19MAR2013 / 06:00 (169) \cell +\pard\intbl\qc\fs16 Month 24 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 321 N CS \cell -\pard\intbl\qc\fs16 150 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 -375 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 20FEB2014 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 51 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs16 05JAN2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 164 N CS \cell -\pard\intbl\qc\fs16 -7 \cell +\pard\intbl\qc\fs16 474 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06MAR2014 / 05:00 (41) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 18JAN2013 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 274 N CS \cell -\pard\intbl\qc\fs16 103 \cell +\pard\intbl\qc\fs16 471 \cell +\pard\intbl\qc\fs16 -3 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 21MAR2014 / 05:00 (56) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 07FEB2013 / 06:00 (34) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 76 N CS \cell -\pard\intbl\qc\fs16 -95 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 -470 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6551 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7264 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12077 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2326 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3757 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7111 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7827 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10063 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10599 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11270 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11896 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17APR2014 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 05JAN2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 102 N CS \cell -\pard\intbl\qc\fs16 -69 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 290 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3209 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6551 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7264 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10607 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11409 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12077 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx940 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1521 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2326 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3757 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7111 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7827 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10063 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10599 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11270 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11896 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2470,20 +2675,22 @@ \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7264 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2326 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3757 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7111 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10063 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10599 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11270 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11896 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell @@ -2494,6 +2701,7 @@ \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } \par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} diff --git a/tests/testthat/_snaps/lsfecg02part2/lsfecg02part2of3.rtf b/tests/testthat/_snaps/lsfecg02/lsfecg02.rtf old mode 100755 new mode 100644 similarity index 53% rename from tests/testthat/_snaps/lsfecg02part2/lsfecg02part2of3.rtf rename to tests/testthat/_snaps/lsfecg02/lsfecg02.rtf index 997b68d9..6b00039d --- a/tests/testthat/_snaps/lsfecg02part2/lsfecg02part2of3.rtf +++ b/tests/testthat/_snaps/lsfecg02/lsfecg02.rtf @@ -6,13 +6,15 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3610 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3566 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6908 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8111 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10339 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11409 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12077 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSFECG02PART2OF3:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7576 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9493 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11275 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11899 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSFECG02:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -30,12 +32,13 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3610 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3566 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6908 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8111 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10339 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11409 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12077 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7576 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9493 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11275 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11899 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell @@ -44,8 +47,9 @@ \pard\intbl\qc\fs16 \keepn\trhdr Visit \cell \pard\intbl\qc\fs16 \keepn\trhdr Time Point \cell \pard\intbl\qc\fs16 \keepn\trhdr Result \cell -\pard\intbl\qc\fs16 \keepn\trhdr Change from Baseline \cell +\pard\intbl\qc\fs16 \keepn\trhdr Change From Baseline \cell \pard\intbl\qc\fs16 \keepn\trhdr Criteria \cell +\pard\intbl\qc\fs16 \keepn\trhdr Treatment-emergent? \cell \row } @@ -54,22 +58,24 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 71 / M / Asian \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / Multiple \cell +\pard\intbl\qc\fs16 Interpretation \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 38 N NCS \cell +\pard\intbl\qc\fs16 ABNORMAL, CS NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 <50 \cell \row } @@ -78,22 +84,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 195 N CS \cell -\pard\intbl\qc\fs16 157 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 ABNORMAL, CS NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -102,22 +110,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 285 N CS \cell -\pard\intbl\qc\fs16 247 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 ABNORMAL, CS CS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -126,22 +136,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 499 N CS \cell -\pard\intbl\qc\fs16 461 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 25 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -150,22 +162,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 343 N CS \cell -\pard\intbl\qc\fs16 305 \cell +\pard\intbl\qc\fs16 538 \cell +\pard\intbl\qc\fs16 513 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -174,22 +188,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 309 N CS \cell -\pard\intbl\qc\fs16 271 \cell +\pard\intbl\qc\fs16 518 \cell +\pard\intbl\qc\fs16 493 \cell \pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -198,22 +214,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 RR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 458 N CS \cell -\pard\intbl\qc\fs16 420 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 567 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -222,22 +240,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 19 N NCS \cell -\pard\intbl\qc\fs16 -19 \cell -\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 376 \cell +\pard\intbl\qc\fs16 -191 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -246,22 +266,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 194 N CS \cell -\pard\intbl\qc\fs16 156 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 98 \cell +\pard\intbl\qc\fs16 -469 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -270,20 +292,22 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Interpretation \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 QRS Duration, Aggregate (ms) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell +\pard\intbl\qc\fs16 507 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row @@ -294,22 +318,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 350 \cell +\pard\intbl\qc\fs16 -157 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -318,22 +344,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 353 \cell +\pard\intbl\qc\fs16 -154 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -342,20 +370,22 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 QT Interval, Corrected (ms) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell +\pard\intbl\qc\fs16 347 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row @@ -366,22 +396,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 494 \cell +\pard\intbl\qc\fs16 147 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -390,22 +422,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 247 \cell +\pard\intbl\qc\fs16 -100 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -414,20 +448,22 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 QTcB Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell +\pard\intbl\qc\fs16 214 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row @@ -438,22 +474,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 394 \cell +\pard\intbl\qc\fs16 180 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -462,22 +500,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 329 \cell +\pard\intbl\qc\fs16 115 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -486,22 +526,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 QTcF Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 370 H CS \cell +\pard\intbl\qc\fs16 503 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >200 \cell \row } @@ -510,22 +552,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 363 H CS \cell -\pard\intbl\qc\fs16 -7 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 456 \cell +\pard\intbl\qc\fs16 -47 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -534,22 +578,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 98 H NCS \cell -\pard\intbl\qc\fs16 -272 \cell -\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 411 \cell +\pard\intbl\qc\fs16 -92 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -558,21 +604,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 196 N NCS \cell -\pard\intbl\qc\fs16 -174 \cell +\pard\intbl\qc\fs16 456 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >200 \cell \pard\intbl\qc\fs16 \cell \row } @@ -582,22 +630,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 333 H CS \cell -\pard\intbl\qc\fs16 -37 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 197 \cell +\pard\intbl\qc\fs16 -259 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -606,22 +656,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 149 H NCS \cell -\pard\intbl\qc\fs16 -221 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 301 \cell +\pard\intbl\qc\fs16 -155 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -630,22 +682,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Interpretation \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 NORMAL \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Month 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 201 H CS \cell -\pard\intbl\qc\fs16 -169 \cell -\pard\intbl\qc\fs16 >200 \cell \row } @@ -654,22 +708,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 530 H CS \cell -\pard\intbl\qc\fs16 160 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 ABNORMAL, NCS NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -678,22 +734,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 596 H CS \cell -\pard\intbl\qc\fs16 226 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 417 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -702,22 +760,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 241 N NCS \cell -\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Month 1 \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 568 \cell +\pard\intbl\qc\fs16 151 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -726,21 +786,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell +\pard\intbl\qc\fs16 RR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 179 N NCS \cell -\pard\intbl\qc\fs16 -62 \cell +\pard\intbl\qc\fs16 77 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } @@ -750,22 +812,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 520 N NCS \cell -\pard\intbl\qc\fs16 279 \cell +\pard\intbl\qc\fs16 535 \cell +\pard\intbl\qc\fs16 458 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -774,21 +838,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 QRS Duration, Aggregate (ms) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 419 N NCS \cell -\pard\intbl\qc\fs16 178 \cell +\pard\intbl\qc\fs16 25 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } @@ -798,22 +864,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 493 N NCS \cell -\pard\intbl\qc\fs16 252 \cell +\pard\intbl\qc\fs16 279 \cell +\pard\intbl\qc\fs16 254 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -822,21 +890,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 QT Interval, Corrected (ms) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 141 N NCS \cell -\pard\intbl\qc\fs16 -100 \cell +\pard\intbl\qc\fs16 405 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } @@ -846,22 +916,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 266 N NCS \cell -\pard\intbl\qc\fs16 25 \cell +\pard\intbl\qc\fs16 238 \cell +\pard\intbl\qc\fs16 -167 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -870,21 +942,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 QTcB Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 184 N NCS \cell -\pard\intbl\qc\fs16 -57 \cell +\pard\intbl\qc\fs16 459 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } @@ -894,22 +968,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 592 N NCS \cell -\pard\intbl\qc\fs16 351 \cell +\pard\intbl\qc\fs16 220 \cell +\pard\intbl\qc\fs16 -239 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -918,20 +994,22 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 QTcF Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 230 H NCS \cell +\pard\intbl\qc\fs16 247 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row @@ -942,22 +1020,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 278 H NCS \cell -\pard\intbl\qc\fs16 48 \cell +\pard\intbl\qc\fs16 460 \cell +\pard\intbl\qc\fs16 213 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -966,21 +1046,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 241 N NCS \cell -\pard\intbl\qc\fs16 11 \cell +\pard\intbl\qc\fs16 544 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >200 \cell \pard\intbl\qc\fs16 \cell \row } @@ -990,22 +1072,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 215 L NCS \cell -\pard\intbl\qc\fs16 -15 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 222 \cell +\pard\intbl\qc\fs16 -322 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1014,22 +1098,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Interpretation \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 NORMAL \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 337 H NCS \cell -\pard\intbl\qc\fs16 107 \cell -\pard\intbl\qc\fs16 \cell \row } @@ -1038,22 +1124,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 508 H CS \cell -\pard\intbl\qc\fs16 278 \cell +\pard\intbl\qc\fs16 ABNORMAL, CS CS \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1062,22 +1150,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 402 H NCS \cell -\pard\intbl\qc\fs16 172 \cell +\pard\intbl\qc\fs16 NORMAL \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1086,22 +1176,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 332 H NCS \cell -\pard\intbl\qc\fs16 102 \cell +\pard\intbl\qc\fs16 ABNORMAL, CS CS \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1110,22 +1202,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 440 H NCS \cell -\pard\intbl\qc\fs16 210 \cell +\pard\intbl\qc\fs16 ABNORMAL, NCS NCS \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1134,21 +1228,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 319 H NCS \cell +\pard\intbl\qc\fs16 423 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >100 \cell \pard\intbl\qc\fs16 \cell \row } @@ -1158,22 +1254,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 367 H NCS \cell -\pard\intbl\qc\fs16 48 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 -418 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1182,22 +1280,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell \pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 473 H NCS \cell -\pard\intbl\qc\fs16 154 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 127 \cell +\pard\intbl\qc\fs16 -296 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1206,22 +1306,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell \pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 423 H NCS \cell -\pard\intbl\qc\fs16 104 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 48 \cell +\pard\intbl\qc\fs16 -375 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1230,22 +1332,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell \pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 336 H NCS \cell -\pard\intbl\qc\fs16 17 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 475 \cell +\pard\intbl\qc\fs16 52 \cell +\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1254,21 +1358,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 RR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 393 H NCS \cell -\pard\intbl\qc\fs16 74 \cell +\pard\intbl\qc\fs16 526 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } @@ -1278,22 +1384,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 287 H NCS \cell -\pard\intbl\qc\fs16 -32 \cell +\pard\intbl\qc\fs16 528 \cell +\pard\intbl\qc\fs16 2 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1302,22 +1410,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 374 H NCS \cell -\pard\intbl\qc\fs16 55 \cell +\pard\intbl\qc\fs16 355 \cell +\pard\intbl\qc\fs16 -171 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1326,22 +1436,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 348 H NCS \cell -\pard\intbl\qc\fs16 29 \cell +\pard\intbl\qc\fs16 418 \cell +\pard\intbl\qc\fs16 -108 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1350,22 +1462,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcF Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 379 H NCS \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 13 \cell +\pard\intbl\qc\fs16 -513 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1374,21 +1488,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell +\pard\intbl\qc\fs16 QRS Duration, Aggregate (ms) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 356 H NCS \cell -\pard\intbl\qc\fs16 -23 \cell +\pard\intbl\qc\fs16 298 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } @@ -1398,22 +1514,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 452 H NCS \cell -\pard\intbl\qc\fs16 73 \cell +\pard\intbl\qc\fs16 252 \cell +\pard\intbl\qc\fs16 -46 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1422,22 +1540,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 300 N NCS \cell -\pard\intbl\qc\fs16 -79 \cell +\pard\intbl\qc\fs16 331 \cell +\pard\intbl\qc\fs16 33 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1446,22 +1566,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 303 H NCS \cell -\pard\intbl\qc\fs16 -76 \cell +\pard\intbl\qc\fs16 431 \cell +\pard\intbl\qc\fs16 133 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1470,22 +1592,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 269 H NCS \cell -\pard\intbl\qc\fs16 -110 \cell +\pard\intbl\qc\fs16 544 \cell +\pard\intbl\qc\fs16 246 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1494,21 +1618,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 QT Interval, Corrected (ms) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 352 H NCS \cell -\pard\intbl\qc\fs16 -27 \cell +\pard\intbl\qc\fs16 398 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } @@ -1518,22 +1644,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 261 H NCS \cell -\pard\intbl\qc\fs16 -118 \cell +\pard\intbl\qc\fs16 322 \cell +\pard\intbl\qc\fs16 -76 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1542,22 +1670,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 348 H NCS \cell -\pard\intbl\qc\fs16 -31 \cell +\pard\intbl\qc\fs16 485 \cell +\pard\intbl\qc\fs16 87 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1566,22 +1696,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 53 L NCS \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 497 \cell +\pard\intbl\qc\fs16 99 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1590,22 +1722,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 476 L NCS \cell -\pard\intbl\qc\fs16 423 \cell +\pard\intbl\qc\fs16 293 \cell +\pard\intbl\qc\fs16 -105 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1614,21 +1748,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell +\pard\intbl\qc\fs16 QTcB Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 498 L NCS \cell -\pard\intbl\qc\fs16 445 \cell +\pard\intbl\qc\fs16 467 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } @@ -1638,22 +1774,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 212 L NCS \cell -\pard\intbl\qc\fs16 159 \cell +\pard\intbl\qc\fs16 422 \cell +\pard\intbl\qc\fs16 -45 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1662,22 +1800,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 469 L NCS \cell -\pard\intbl\qc\fs16 416 \cell +\pard\intbl\qc\fs16 457 \cell +\pard\intbl\qc\fs16 -10 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1686,22 +1826,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 419 L NCS \cell -\pard\intbl\qc\fs16 366 \cell +\pard\intbl\qc\fs16 260 \cell +\pard\intbl\qc\fs16 -207 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1710,22 +1852,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 54 L NCS \cell -\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 262 \cell +\pard\intbl\qc\fs16 -205 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1734,21 +1878,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 QTcF Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 479 L NCS \cell -\pard\intbl\qc\fs16 426 \cell +\pard\intbl\qc\fs16 360 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } @@ -1758,22 +1904,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 137 L NCS \cell -\pard\intbl\qc\fs16 84 \cell +\pard\intbl\qc\fs16 215 \cell +\pard\intbl\qc\fs16 -145 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1782,22 +1930,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 77 / F / White \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 01JUL2014 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 257 N CS \cell +\pard\intbl\qc\fs16 236 \cell +\pard\intbl\qc\fs16 -124 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1806,22 +1956,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 15JUL2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 176 N CS \cell -\pard\intbl\qc\fs16 -81 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 457 \cell +\pard\intbl\qc\fs16 97 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1830,22 +1982,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29JUL2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 385 N CS \cell -\pard\intbl\qc\fs16 128 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 441 \cell +\pard\intbl\qc\fs16 81 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1854,22 +2008,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 140 N CS \cell -\pard\intbl\qc\fs16 -117 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 105 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1878,22 +2034,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26AUG2014 / 04:00 (57) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 23 N NCS \cell -\pard\intbl\qc\fs16 -234 \cell -\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 61 \cell +\pard\intbl\qc\fs16 -44 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1902,22 +2060,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25SEP2014 / 04:00 (87) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 465 N CS \cell -\pard\intbl\qc\fs16 208 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 151 \cell +\pard\intbl\qc\fs16 46 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1926,22 +2086,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 21OCT2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 129 N CS \cell -\pard\intbl\qc\fs16 -128 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 92 \cell +\pard\intbl\qc\fs16 -13 \cell +\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1950,22 +2112,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 18NOV2014 / 05:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Month 9 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 164 N CS \cell -\pard\intbl\qc\fs16 -93 \cell -\pard\intbl\qc\fs16 >100 \cell +\pard\intbl\qc\fs16 351 \cell +\pard\intbl\qc\fs16 246 \cell +\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1974,22 +2138,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 79 / Female / Not reported \cell +\pard\intbl\qc\fs16 Interpretation \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 NORMAL \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17DEC2014 / 05:00 (170) \cell -\pard\intbl\qc\fs16 Month 24 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 587 N CS \cell -\pard\intbl\qc\fs16 330 \cell -\pard\intbl\qc\fs16 >100 \cell \row } @@ -1998,22 +2164,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Interpretation \cell -\pard\intbl\qc\fs16 01JUL2014 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell +\pard\intbl\qc\fs16 ABNORMAL, CS NCS \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2022,21 +2190,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 15JUL2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell +\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell +\pard\intbl\qc\fs16 25 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <50 \cell \pard\intbl\qc\fs16 \cell \row } @@ -2046,22 +2216,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29JUL2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 45 \cell +\pard\intbl\qc\fs16 20 \cell +\pard\intbl\qc\fs16 <50 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2070,20 +2242,22 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 RR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL NCS \cell +\pard\intbl\qc\fs16 326 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row @@ -2094,22 +2268,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26AUG2014 / 04:00 (57) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 390 \cell +\pard\intbl\qc\fs16 64 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2118,20 +2294,22 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25SEP2014 / 04:00 (87) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 QRS Duration, Aggregate (ms) \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell +\pard\intbl\qc\fs16 278 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row @@ -2142,22 +2320,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 21OCT2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 123 \cell +\pard\intbl\qc\fs16 -155 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2166,20 +2346,22 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 18NOV2014 / 05:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 QT Interval, Corrected (ms) \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell +\pard\intbl\qc\fs16 385 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row @@ -2190,22 +2372,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17DEC2014 / 05:00 (170) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL NCS \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 279 \cell +\pard\intbl\qc\fs16 -106 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2214,22 +2398,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 01JUL2014 / 04:00 (1) \cell +\pard\intbl\qc\fs16 QTcB Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell \pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 472 H CS \cell +\pard\intbl\qc\fs16 249 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >200 \cell \row } @@ -2238,22 +2424,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 15JUL2014 / 04:00 (15) \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell \pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 68 H NCS \cell -\pard\intbl\qc\fs16 -404 \cell -\pard\intbl\qc\fs16 <120 \cell +\pard\intbl\qc\fs16 323 \cell +\pard\intbl\qc\fs16 74 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2262,21 +2450,23 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29JUL2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell +\pard\intbl\qc\fs16 QTcF Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 168 H NCS \cell -\pard\intbl\qc\fs16 -304 \cell +\pard\intbl\qc\fs16 251 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \row } @@ -2286,22 +2476,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 254 H CS \cell -\pard\intbl\qc\fs16 -218 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 290 \cell +\pard\intbl\qc\fs16 39 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2310,22 +2502,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26AUG2014 / 04:00 (57) \cell -\pard\intbl\qc\fs16 Month 9 \cell +\pard\intbl\qc\fs16 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 513 H CS \cell -\pard\intbl\qc\fs16 41 \cell +\pard\intbl\qc\fs16 390 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2334,22 +2528,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25SEP2014 / 04:00 (87) \cell -\pard\intbl\qc\fs16 Month 12 \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 273 H CS \cell -\pard\intbl\qc\fs16 -199 \cell +\pard\intbl\qc\fs16 280 \cell +\pard\intbl\qc\fs16 -110 \cell \pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2358,22 +2554,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Interpretation \cell +\pard\intbl\qc\fs16 15FEB2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 ABNORMAL, NCS NCS \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 21OCT2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 137 H NCS \cell -\pard\intbl\qc\fs16 -335 \cell -\pard\intbl\qc\fs16 \cell \row } @@ -2382,22 +2580,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 18NOV2014 / 05:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell +\pard\intbl\qc\fs16 02MAR2013 / 06:00 (16) \cell +\pard\intbl\qc\fs16 Month 1 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 512 H CS \cell -\pard\intbl\qc\fs16 40 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 ABNORMAL, CS NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2406,22 +2606,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17DEC2014 / 05:00 (170) \cell -\pard\intbl\qc\fs16 Month 24 \cell +\pard\intbl\qc\fs16 16MAR2013 / 06:00 (30) \cell +\pard\intbl\qc\fs16 Month 3 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 579 H CS \cell -\pard\intbl\qc\fs16 107 \cell -\pard\intbl\qc\fs16 >200 \cell +\pard\intbl\qc\fs16 ABNORMAL, NCS NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2430,22 +2632,24 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3610 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3566 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6908 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8111 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10339 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11409 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12077 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7576 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9493 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs16 01JUL2014 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 25MAR2013 / 06:00 (39) \cell +\pard\intbl\qc\fs16 Month 6 \cell \pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 406 N NCS \cell +\pard\intbl\qc\fs16 ABNORMAL, NCS NCS \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2454,12 +2658,13 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3610 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3566 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6908 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8111 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10339 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11409 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12077 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7576 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9493 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10607 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11275 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11899 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2470,6 +2675,7 @@ \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } @@ -2478,12 +2684,13 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3610 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3566 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6908 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10339 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12077 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7576 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell @@ -2494,6 +2701,7 @@ \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } \par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} diff --git a/tests/testthat/_snaps/lsfecg02part1/lsfecg02part1of3.rtf b/tests/testthat/_snaps/lsfecg02part1/lsfecg02part1of3.rtf deleted file mode 100755 index a2f33cfa..00000000 --- a/tests/testthat/_snaps/lsfecg02part1/lsfecg02part1of3.rtf +++ /dev/null @@ -1,2500 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx943 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2334 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4040 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7406 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8079 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10323 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11400 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12073 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSFECG02PART1OF3:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx943 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2334 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4040 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7406 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8079 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10323 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11400 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12073 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell -\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell -\pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell -\pard\intbl\qc\fs16 \keepn\trhdr ECG Parameter (unit) \cell -\pard\intbl\qc\fs16 \keepn\trhdr Assessment Date / Time (Study Day\super a\nosupersub ) \cell -\pard\intbl\qc\fs16 \keepn\trhdr Visit \cell -\pard\intbl\qc\fs16 \keepn\trhdr Time Point \cell -\pard\intbl\qc\fs16 \keepn\trhdr Result \cell -\pard\intbl\qc\fs16 \keepn\trhdr Change from Baseline \cell -\pard\intbl\qc\fs16 \keepn\trhdr Criteria \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 01-701-1033 \cell -\pard\intbl\qc\fs16 74 / M / Multiple \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 18MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 25 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 <50 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01APR2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 538 N CS \cell -\pard\intbl\qc\fs16 513 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14APR2014 / 04:00 (28) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 518 N CS \cell -\pard\intbl\qc\fs16 493 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Interpretation \cell -\pard\intbl\qc\fs16 18MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01APR2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14APR2014 / 04:00 (28) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 18MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 456 H CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01APR2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 197 H NCS \cell -\pard\intbl\qc\fs16 -259 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14APR2014 / 04:00 (28) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 301 N CS \cell -\pard\intbl\qc\fs16 -155 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs16 18MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 507 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01APR2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 350 N NCS \cell -\pard\intbl\qc\fs16 -157 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14APR2014 / 04:00 (28) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 353 N NCS \cell -\pard\intbl\qc\fs16 -154 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs16 18MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 347 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01APR2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 494 H NCS \cell -\pard\intbl\qc\fs16 147 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14APR2014 / 04:00 (28) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 247 N NCS \cell -\pard\intbl\qc\fs16 -100 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 18MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 214 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01APR2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 394 H NCS \cell -\pard\intbl\qc\fs16 180 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14APR2014 / 04:00 (28) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 329 H NCS \cell -\pard\intbl\qc\fs16 115 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcF Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 18MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 503 H CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01APR2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 456 H NCS \cell -\pard\intbl\qc\fs16 -47 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14APR2014 / 04:00 (28) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 411 H NCS \cell -\pard\intbl\qc\fs16 -92 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 18MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 567 L NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01APR2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 376 L NCS \cell -\pard\intbl\qc\fs16 -191 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14APR2014 / 04:00 (28) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 98 L NCS \cell -\pard\intbl\qc\fs16 -469 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1111 \cell -\pard\intbl\qc\fs16 81 / F / White \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 07SEP2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 417 N CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17SEP2012 / 04:00 (11) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 568 N CS \cell -\pard\intbl\qc\fs16 151 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Interpretation \cell -\pard\intbl\qc\fs16 07SEP2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17SEP2012 / 04:00 (11) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 07SEP2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 544 H CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17SEP2012 / 04:00 (11) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 222 H CS \cell -\pard\intbl\qc\fs16 -322 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs16 07SEP2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 25 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17SEP2012 / 04:00 (11) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 279 N NCS \cell -\pard\intbl\qc\fs16 254 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs16 07SEP2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 405 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17SEP2012 / 04:00 (11) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 238 H NCS \cell -\pard\intbl\qc\fs16 -167 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 07SEP2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 459 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17SEP2012 / 04:00 (11) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 220 H NCS \cell -\pard\intbl\qc\fs16 -239 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcF Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 07SEP2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 247 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17SEP2012 / 04:00 (11) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 460 H NCS \cell -\pard\intbl\qc\fs16 213 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 07SEP2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 77 L NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17SEP2012 / 04:00 (11) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 535 L NCS \cell -\pard\intbl\qc\fs16 458 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1115 \cell -\pard\intbl\qc\fs16 84 / M / Black or African American \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 30NOV2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 423 N CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 13DEC2012 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 5 N NCS \cell -\pard\intbl\qc\fs16 -418 \cell -\pard\intbl\qc\fs16 <50 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26DEC2012 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 127 N CS \cell -\pard\intbl\qc\fs16 -296 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10JAN2013 / 05:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 48 N NCS \cell -\pard\intbl\qc\fs16 -375 \cell -\pard\intbl\qc\fs16 <50 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23JAN2013 / 05:00 (55) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 475 N CS \cell -\pard\intbl\qc\fs16 52 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Interpretation \cell -\pard\intbl\qc\fs16 30NOV2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 13DEC2012 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26DEC2012 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10JAN2013 / 05:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23JAN2013 / 05:00 (55) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 30NOV2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 105 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 <120 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 13DEC2012 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 61 H NCS \cell -\pard\intbl\qc\fs16 -44 \cell -\pard\intbl\qc\fs16 <120 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26DEC2012 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 151 H NCS \cell -\pard\intbl\qc\fs16 46 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10JAN2013 / 05:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 92 H NCS \cell -\pard\intbl\qc\fs16 -13 \cell -\pard\intbl\qc\fs16 <120 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23JAN2013 / 05:00 (55) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 351 H CS \cell -\pard\intbl\qc\fs16 246 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs16 30NOV2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 298 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 13DEC2012 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 252 N NCS \cell -\pard\intbl\qc\fs16 -46 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26DEC2012 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 331 N NCS \cell -\pard\intbl\qc\fs16 33 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10JAN2013 / 05:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 431 N NCS \cell -\pard\intbl\qc\fs16 133 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23JAN2013 / 05:00 (55) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 544 N NCS \cell -\pard\intbl\qc\fs16 246 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs16 30NOV2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 398 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 13DEC2012 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 322 H NCS \cell -\pard\intbl\qc\fs16 -76 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26DEC2012 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 485 H NCS \cell -\pard\intbl\qc\fs16 87 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10JAN2013 / 05:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 497 N NCS \cell -\pard\intbl\qc\fs16 99 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23JAN2013 / 05:00 (55) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 293 N NCS \cell -\pard\intbl\qc\fs16 -105 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 30NOV2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 467 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 13DEC2012 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 422 H NCS \cell -\pard\intbl\qc\fs16 -45 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26DEC2012 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 457 H NCS \cell -\pard\intbl\qc\fs16 -10 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10JAN2013 / 05:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 260 H NCS \cell -\pard\intbl\qc\fs16 -207 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23JAN2013 / 05:00 (55) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 262 H NCS \cell -\pard\intbl\qc\fs16 -205 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcF Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 30NOV2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 360 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 13DEC2012 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 215 H NCS \cell -\pard\intbl\qc\fs16 -145 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26DEC2012 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 236 H NCS \cell -\pard\intbl\qc\fs16 -124 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10JAN2013 / 05:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 457 H NCS \cell -\pard\intbl\qc\fs16 97 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23JAN2013 / 05:00 (55) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 441 H NCS \cell -\pard\intbl\qc\fs16 81 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 30NOV2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 526 L NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 13DEC2012 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 528 L NCS \cell -\pard\intbl\qc\fs16 2 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26DEC2012 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 355 L NCS \cell -\pard\intbl\qc\fs16 -171 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10JAN2013 / 05:00 (42) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 418 L NCS \cell -\pard\intbl\qc\fs16 -108 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23JAN2013 / 05:00 (55) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 13 N NCS \cell -\pard\intbl\qc\fs16 -513 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1181 \cell -\pard\intbl\qc\fs16 79 / F / Not reported \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 05DEC2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 25 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 <50 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 12DEC2013 / 05:00 (8) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 45 N NCS \cell -\pard\intbl\qc\fs16 20 \cell -\pard\intbl\qc\fs16 <50 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Interpretation \cell -\pard\intbl\qc\fs16 05DEC2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 12DEC2013 / 05:00 (8) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 05DEC2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 390 H CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 12DEC2013 / 05:00 (8) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 280 H CS \cell -\pard\intbl\qc\fs16 -110 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs16 05DEC2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 278 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 12DEC2013 / 05:00 (8) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 123 N NCS \cell -\pard\intbl\qc\fs16 -155 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs16 05DEC2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 385 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 12DEC2013 / 05:00 (8) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 279 N NCS \cell -\pard\intbl\qc\fs16 -106 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 05DEC2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 249 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 12DEC2013 / 05:00 (8) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 323 H NCS \cell -\pard\intbl\qc\fs16 74 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcF Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 05DEC2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 251 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 12DEC2013 / 05:00 (8) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 290 H NCS \cell -\pard\intbl\qc\fs16 39 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 05DEC2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 326 L NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 12DEC2013 / 05:00 (8) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 390 L NCS \cell -\pard\intbl\qc\fs16 64 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1188 \cell -\pard\intbl\qc\fs16 71 / M / White \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 15FEB2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 583 N CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02MAR2013 / 05:00 (16) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 201 N CS \cell -\pard\intbl\qc\fs16 -382 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 16MAR2013 / 05:00 (30) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 347 N CS \cell -\pard\intbl\qc\fs16 -236 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx943 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1526 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2334 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4040 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7406 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8079 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10323 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11400 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12073 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25MAR2013 / 05:00 (39) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 548 N CS \cell -\pard\intbl\qc\fs16 -35 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx943 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1526 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2334 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4040 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7406 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8079 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10323 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11400 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12073 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4040 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8079 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10323 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11400 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12073 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} -\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} -} \ No newline at end of file diff --git a/tests/testthat/_snaps/lsfecg02part3/lsfecg02part3of3.rtf b/tests/testthat/_snaps/lsfecg02part3/lsfecg02part3of3.rtf deleted file mode 100755 index cd036143..00000000 --- a/tests/testthat/_snaps/lsfecg02part3/lsfecg02part3of3.rtf +++ /dev/null @@ -1,2500 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx805 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1387 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4025 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7379 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8095 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10331 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11404 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12075 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSFECG02PART3OF3:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx805 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1387 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2192 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4025 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7379 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8095 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10331 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11404 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12075 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell -\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell -\pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell -\pard\intbl\qc\fs16 \keepn\trhdr ECG Parameter (unit) \cell -\pard\intbl\qc\fs16 \keepn\trhdr Assessment Date / Time (Study Day\super a\nosupersub ) \cell -\pard\intbl\qc\fs16 \keepn\trhdr Visit \cell -\pard\intbl\qc\fs16 \keepn\trhdr Time Point \cell -\pard\intbl\qc\fs16 \keepn\trhdr Result \cell -\pard\intbl\qc\fs16 \keepn\trhdr Change from Baseline \cell -\pard\intbl\qc\fs16 \keepn\trhdr Criteria \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Placebo \cell -\pard\intbl\qc\fs16 01-701-1023 \cell -\pard\intbl\qc\fs16 64 / M / Black or African American \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 05AUG2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 164 N CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2012 / 04:00 (23) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 50 N NCS \cell -\pard\intbl\qc\fs16 -114 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02SEP2012 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 73 N NCS \cell -\pard\intbl\qc\fs16 -91 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Interpretation \cell -\pard\intbl\qc\fs16 05AUG2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2012 / 04:00 (23) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02SEP2012 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 05AUG2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 532 H CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2012 / 04:00 (23) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 582 H CS \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02SEP2012 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 243 H CS \cell -\pard\intbl\qc\fs16 -289 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs16 05AUG2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 344 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2012 / 04:00 (23) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 28 N NCS \cell -\pard\intbl\qc\fs16 -316 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02SEP2012 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 18 N NCS \cell -\pard\intbl\qc\fs16 -326 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs16 05AUG2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 399 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2012 / 04:00 (23) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 471 N NCS \cell -\pard\intbl\qc\fs16 72 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02SEP2012 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 290 H NCS \cell -\pard\intbl\qc\fs16 -109 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 05AUG2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 208 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2012 / 04:00 (23) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 454 H NCS \cell -\pard\intbl\qc\fs16 246 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02SEP2012 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 353 H NCS \cell -\pard\intbl\qc\fs16 145 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcF Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 05AUG2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 290 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2012 / 04:00 (23) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 227 H NCS \cell -\pard\intbl\qc\fs16 -63 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02SEP2012 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 305 H NCS \cell -\pard\intbl\qc\fs16 15 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 05AUG2012 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 490 L NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2012 / 04:00 (23) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 491 L NCS \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02SEP2012 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 548 L NCS \cell -\pard\intbl\qc\fs16 58 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1047 \cell -\pard\intbl\qc\fs16 85 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 12FEB2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 363 N CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25FEB2013 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 385 N CS \cell -\pard\intbl\qc\fs16 22 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10MAR2013 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 402 N CS \cell -\pard\intbl\qc\fs16 39 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Interpretation \cell -\pard\intbl\qc\fs16 12FEB2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25FEB2013 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10MAR2013 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 12FEB2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 320 H CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25FEB2013 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 129 H NCS \cell -\pard\intbl\qc\fs16 -191 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10MAR2013 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 114 H NCS \cell -\pard\intbl\qc\fs16 -206 \cell -\pard\intbl\qc\fs16 <120 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs16 12FEB2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 296 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25FEB2013 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 233 N NCS \cell -\pard\intbl\qc\fs16 -63 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10MAR2013 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 41 N NCS \cell -\pard\intbl\qc\fs16 -255 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs16 12FEB2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 351 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25FEB2013 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 344 N NCS \cell -\pard\intbl\qc\fs16 -7 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10MAR2013 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 236 H NCS \cell -\pard\intbl\qc\fs16 -115 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 12FEB2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 344 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25FEB2013 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 429 H NCS \cell -\pard\intbl\qc\fs16 85 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10MAR2013 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 369 H NCS \cell -\pard\intbl\qc\fs16 25 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcF Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 12FEB2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 465 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25FEB2013 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 363 H NCS \cell -\pard\intbl\qc\fs16 -102 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10MAR2013 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 361 H NCS \cell -\pard\intbl\qc\fs16 -104 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 12FEB2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 358 L NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25FEB2013 / 05:00 (14) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 64 L NCS \cell -\pard\intbl\qc\fs16 -294 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10MAR2013 / 05:00 (27) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 564 L NCS \cell -\pard\intbl\qc\fs16 206 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1118 \cell -\pard\intbl\qc\fs16 52 / M / Other \cell -\pard\intbl\qc\fs16 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs16 12MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 378 N CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26MAR2014 / 05:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 341 N CS \cell -\pard\intbl\qc\fs16 -37 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09APR2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 220 N CS \cell -\pard\intbl\qc\fs16 -158 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23APR2014 / 04:00 (43) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 160 N CS \cell -\pard\intbl\qc\fs16 -218 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 08MAY2014 / 04:00 (58) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 447 N CS \cell -\pard\intbl\qc\fs16 69 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 05JUN2014 / 04:00 (86) \cell -\pard\intbl\qc\fs16 Month 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 241 N CS \cell -\pard\intbl\qc\fs16 -137 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02JUL2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 535 N CS \cell -\pard\intbl\qc\fs16 157 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 30JUL2014 / 04:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 406 N CS \cell -\pard\intbl\qc\fs16 28 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2014 / 04:00 (169) \cell -\pard\intbl\qc\fs16 Month 24 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 228 N CS \cell -\pard\intbl\qc\fs16 -150 \cell -\pard\intbl\qc\fs16 >100 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Interpretation \cell -\pard\intbl\qc\fs16 12MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26MAR2014 / 05:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09APR2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23APR2014 / 04:00 (43) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 08MAY2014 / 04:00 (58) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 05JUN2014 / 04:00 (86) \cell -\pard\intbl\qc\fs16 Month 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02JUL2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 30JUL2014 / 04:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 NORMAL \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2014 / 04:00 (169) \cell -\pard\intbl\qc\fs16 Month 24 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 ABNORMAL CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 12MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 166 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26MAR2014 / 05:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 54 H NCS \cell -\pard\intbl\qc\fs16 -112 \cell -\pard\intbl\qc\fs16 <120 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09APR2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 259 H CS \cell -\pard\intbl\qc\fs16 93 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23APR2014 / 04:00 (43) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 383 H CS \cell -\pard\intbl\qc\fs16 217 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 08MAY2014 / 04:00 (58) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 411 H CS \cell -\pard\intbl\qc\fs16 245 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 05JUN2014 / 04:00 (86) \cell -\pard\intbl\qc\fs16 Month 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 321 H CS \cell -\pard\intbl\qc\fs16 155 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02JUL2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 308 H CS \cell -\pard\intbl\qc\fs16 142 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 30JUL2014 / 04:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 172 H NCS \cell -\pard\intbl\qc\fs16 6 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2014 / 04:00 (169) \cell -\pard\intbl\qc\fs16 Month 24 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 517 H CS \cell -\pard\intbl\qc\fs16 351 \cell -\pard\intbl\qc\fs16 >200 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs16 12MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 129 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26MAR2014 / 05:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 66 N NCS \cell -\pard\intbl\qc\fs16 -63 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09APR2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 520 N NCS \cell -\pard\intbl\qc\fs16 391 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23APR2014 / 04:00 (43) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 120 N NCS \cell -\pard\intbl\qc\fs16 -9 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 08MAY2014 / 04:00 (58) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 349 N NCS \cell -\pard\intbl\qc\fs16 220 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 05JUN2014 / 04:00 (86) \cell -\pard\intbl\qc\fs16 Month 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 379 N NCS \cell -\pard\intbl\qc\fs16 250 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02JUL2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 333 N NCS \cell -\pard\intbl\qc\fs16 204 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 30JUL2014 / 04:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 241 N NCS \cell -\pard\intbl\qc\fs16 112 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2014 / 04:00 (169) \cell -\pard\intbl\qc\fs16 Month 24 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 439 N NCS \cell -\pard\intbl\qc\fs16 310 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs16 12MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 272 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26MAR2014 / 05:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 291 N NCS \cell -\pard\intbl\qc\fs16 19 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09APR2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 330 N NCS \cell -\pard\intbl\qc\fs16 58 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23APR2014 / 04:00 (43) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 229 N NCS \cell -\pard\intbl\qc\fs16 -43 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 08MAY2014 / 04:00 (58) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 414 H NCS \cell -\pard\intbl\qc\fs16 142 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 05JUN2014 / 04:00 (86) \cell -\pard\intbl\qc\fs16 Month 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 470 N NCS \cell -\pard\intbl\qc\fs16 198 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02JUL2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 257 H NCS \cell -\pard\intbl\qc\fs16 -15 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 30JUL2014 / 04:00 (141) \cell -\pard\intbl\qc\fs16 Month 18 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 463 H NCS \cell -\pard\intbl\qc\fs16 191 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 27AUG2014 / 04:00 (169) \cell -\pard\intbl\qc\fs16 Month 24 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 299 H NCS \cell -\pard\intbl\qc\fs16 27 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs16 12MAR2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 494 H NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26MAR2014 / 05:00 (15) \cell -\pard\intbl\qc\fs16 Month 1 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 506 H CS \cell -\pard\intbl\qc\fs16 12 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09APR2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Month 3 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 504 H CS \cell -\pard\intbl\qc\fs16 10 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 23APR2014 / 04:00 (43) \cell -\pard\intbl\qc\fs16 Month 6 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 360 H NCS \cell -\pard\intbl\qc\fs16 -134 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 08MAY2014 / 04:00 (58) \cell -\pard\intbl\qc\fs16 Month 9 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 364 H NCS \cell -\pard\intbl\qc\fs16 -130 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 05JUN2014 / 04:00 (86) \cell -\pard\intbl\qc\fs16 Month 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 270 H NCS \cell -\pard\intbl\qc\fs16 -224 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx805 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1387 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2192 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4025 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7379 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8095 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10331 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11404 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12075 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 02JUL2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Month 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 518 H CS \cell -\pard\intbl\qc\fs16 24 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx805 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1387 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2192 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4025 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7379 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8095 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10331 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11404 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12075 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx805 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1387 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2192 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4025 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7379 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8095 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10331 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11404 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12075 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} -\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} -} \ No newline at end of file diff --git a/tests/testthat/_snaps/lsflab01/lsflab01.rtf b/tests/testthat/_snaps/lsflab01/lsflab01.rtf old mode 100755 new mode 100644 index 0e5f1e9f..62eece60 --- a/tests/testthat/_snaps/lsflab01/lsflab01.rtf +++ b/tests/testthat/_snaps/lsflab01/lsflab01.rtf @@ -6,12 +6,13 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3967 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5749 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6551 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3655 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6997 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7666 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8200 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11231 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8780 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9448 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10429 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11097 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11899 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSFLAB01:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -24,6 +25,7 @@ \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } @@ -32,12 +34,13 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3967 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5749 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6551 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3655 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6997 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7666 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8200 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11231 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8780 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9448 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10429 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11097 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11899 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell @@ -47,9 +50,10 @@ \pard\intbl\qc\fs16 \keepn\trhdr Visit \cell \pard\intbl\qc\fs16 \keepn\trhdr Time Point \cell \pard\intbl\qc\fs16 \keepn\trhdr Result \cell -\pard\intbl\qc\fs16 \keepn\trhdr FDA Threshold Level \cell +\pard\intbl\qc\fs16 \keepn\trhdr Criteria Flag \cell \pard\intbl\qc\fs16 \keepn\trhdr Change From Baseline \cell \pard\intbl\qc\fs16 \keepn\trhdr Reference Range \cell +\pard\intbl\qc\fs16 \keepn\trhdr Treatment-emergent? \cell \row } @@ -58,24 +62,26 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 71 / Male / White \cell -\pard\intbl\qc\fs16 Alanine Aminotransferase (U/L) \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 30 N NCS \cell -\pard\intbl\qc\fs16 L2 (>6.0 mmol/L) \cell -\pard\intbl\qc\fs16 4 \cell -\pard\intbl\qc\fs16 6 - 35 \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / Multiple \cell +\pard\intbl\qc\fs16 Albumin (g/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 38 N CS \cell +\pard\intbl\qc\fs16 L3 (<20.0 g/L) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <35 - 46 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -84,24 +90,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 22 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.694 mmol/L) \cell -\pard\intbl\qc\fs16 -4 \cell -\pard\intbl\qc\fs16 <6 - 35 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 41 N NCS \cell +\pard\intbl\qc\fs16 L2 (<25.0 g/L) \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 <35 - <46 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -110,24 +118,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 24 N NCS \cell -\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell -\pard\intbl\qc\fs16 -2 \cell -\pard\intbl\qc\fs16 6 - 35 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 40 N NCS \cell +\pard\intbl\qc\fs16 L2 (<25.0 g/L) \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 <35 - <46 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -136,24 +146,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Calcium (mmol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 2.0708 L CS \cell +\pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 24 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.694 mmol/L) \cell -\pard\intbl\qc\fs16 -2 \cell -\pard\intbl\qc\fs16 <6 - 35 \cell +\pard\intbl\qc\fs16 <2.1 - 2.57 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -162,24 +174,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 00:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 29 N NCS \cell -\pard\intbl\qc\fs16 L3 (>15.0 10^9/L) \cell -\pard\intbl\qc\fs16 3 \cell -\pard\intbl\qc\fs16 6 - 35 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.1706 N NCS \cell +\pard\intbl\qc\fs16 L1 (<2.096 mmol/L) \cell +\pard\intbl\qc\fs16 0.0998 \cell +\pard\intbl\qc\fs16 2.1 - 2.57 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -188,24 +202,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 00:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 33 N NCS \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.1457 N NCS \cell \pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs16 7 \cell -\pard\intbl\qc\fs16 <6 - 35 \cell +\pard\intbl\qc\fs16 0.0749 \cell +\pard\intbl\qc\fs16 <2.1 - <2.57 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -214,24 +230,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11JUL2013 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Chloride (mmol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell \pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 26 N NCS \cell -\pard\intbl\qc\fs16 L1 (125-135 g/L) \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 107 N CS \cell +\pard\intbl\qc\fs16 L3 (<80 mmol/L) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 94 - <112 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 <6 - 35 \cell \row } @@ -240,24 +258,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 00:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 29 N NCS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell -\pard\intbl\qc\fs16 3 \cell -\pard\intbl\qc\fs16 6 - 35 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 107 N NCS \cell +\pard\intbl\qc\fs16 L2 (<88 mmol/L) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 <94 - 112 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -266,24 +286,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 00:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 26 N NCS \cell -\pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs16 0 \cell -\pard\intbl\qc\fs16 <6 - <35 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 105 N CS \cell +\pard\intbl\qc\fs16 L1 (<95 mmol/L) \cell +\pard\intbl\qc\fs16 -2 \cell +\pard\intbl\qc\fs16 <94 - <112 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -292,24 +314,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Creatinine Kinase (U/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 114 N NCS \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 00:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 32 N CS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 6 \cell -\pard\intbl\qc\fs16 6 - <35 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <22 - <198 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -318,24 +342,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Albumin (g/L) \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell \pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 42 N NCS \cell -\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell -\pard\intbl\qc\fs16 -2 \cell -\pard\intbl\qc\fs16 35 - <46 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 93 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 -21 \cell +\pard\intbl\qc\fs16 <22 - <198 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -344,24 +370,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 40 N CS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 -4 \cell -\pard\intbl\qc\fs16 35 - <46 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 116 N NCS \cell +\pard\intbl\qc\fs16 L3 (>10x ULN Enzyme U/L) \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 <22 - <198 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -370,24 +398,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Glucose (mmol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 4.9959 N CS \cell +\pard\intbl\qc\fs16 L1 (fasting >=5.55 mmol/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 42 N NCS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 -2 \cell -\pard\intbl\qc\fs16 35 - <46 \cell +\pard\intbl\qc\fs16 2.8 - 13.9 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -396,24 +426,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 37 N NCS \cell -\pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs16 -7 \cell -\pard\intbl\qc\fs16 <35 - <46 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 5.7175 N CS \cell +\pard\intbl\qc\fs16 L1 (<3.89 mmol/L) \cell +\pard\intbl\qc\fs16 0.7216 \cell +\pard\intbl\qc\fs16 2.8 - 13.9 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -422,24 +454,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 00:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 44 N NCS \cell -\pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs16 0 \cell -\pard\intbl\qc\fs16 35 - 46 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 5.4400 N NCS \cell +\pard\intbl\qc\fs16 L2 (<3.00 mmol/L) \cell +\pard\intbl\qc\fs16 0.4441 \cell +\pard\intbl\qc\fs16 2.8 - <13.9 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -448,24 +482,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Phosphate (mmol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 1.2270 N CS \cell +\pard\intbl\qc\fs16 L2 (<0.646 mmol/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 00:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 39 N CS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 -5 \cell -\pard\intbl\qc\fs16 35 - <46 \cell +\pard\intbl\qc\fs16 0.71 - 1.65 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -474,24 +510,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11JUL2013 / 00:00 (-8) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 44 N NCS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 1.0656 N CS \cell +\pard\intbl\qc\fs16 L1 (<0.807 mmol/L) \cell +\pard\intbl\qc\fs16 -0.1615 \cell +\pard\intbl\qc\fs16 <0.71 - 1.65 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 <35 - <46 \cell \row } @@ -500,24 +538,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 00:00 (27) \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell \pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 41 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.694 mmol/L) \cell -\pard\intbl\qc\fs16 -3 \cell -\pard\intbl\qc\fs16 <35 - <46 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 1.1301 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 -0.0969 \cell +\pard\intbl\qc\fs16 0.71 - <1.65 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -526,24 +566,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Potassium (mmol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 4.1 N NCS \cell +\pard\intbl\qc\fs16 L3 (<3.0 mmol/L) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <3.4 - 5.4 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 00:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 45 N CS \cell -\pard\intbl\qc\fs16 L1 (>1.5x ULN Enzyme U/L) \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 35 - 46 \cell \row } @@ -552,24 +594,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 00:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 40 N NCS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 -4 \cell -\pard\intbl\qc\fs16 35 - <46 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 4.2 N CS \cell +\pard\intbl\qc\fs16 L1 (<3.6 mmol/L) \cell +\pard\intbl\qc\fs16 0.1 \cell +\pard\intbl\qc\fs16 3.4 - <5.4 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -578,24 +622,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alkaline Phosphatase (U/L) \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 46 N NCS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 2 \cell -\pard\intbl\qc\fs16 <35 - 115 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 3.9 N NCS \cell +\pard\intbl\qc\fs16 L1 (<3.6 mmol/L) \cell +\pard\intbl\qc\fs16 -0.2 \cell +\pard\intbl\qc\fs16 3.4 - 5.4 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -604,24 +650,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Sodium (mmol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 145 N NCS \cell +\pard\intbl\qc\fs16 L2 (<130 mmol/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 43 N CS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 -1 \cell -\pard\intbl\qc\fs16 <35 - <115 \cell +\pard\intbl\qc\fs16 <135 - <145 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -630,24 +678,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 47 N CS \cell -\pard\intbl\qc\fs16 L1 (125-135 g/L) \cell -\pard\intbl\qc\fs16 3 \cell -\pard\intbl\qc\fs16 35 - <115 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 140 N NCS \cell +\pard\intbl\qc\fs16 L2 (<130 mmol/L) \cell +\pard\intbl\qc\fs16 -5 \cell +\pard\intbl\qc\fs16 <135 - <145 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -656,24 +706,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 36 N CS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 -8 \cell -\pard\intbl\qc\fs16 35 - <115 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 140 N NCS \cell +\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell +\pard\intbl\qc\fs16 -5 \cell +\pard\intbl\qc\fs16 <135 - <145 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -682,24 +734,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Creatinine (umol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 132.60 N NCS \cell +\pard\intbl\qc\fs16 L2 (>=2x baseline umol/L) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 71 - 141 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 00:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 41 N NCS \cell -\pard\intbl\qc\fs16 L1 (125-135 g/L) \cell -\pard\intbl\qc\fs16 -3 \cell -\pard\intbl\qc\fs16 35 - 115 \cell \row } @@ -708,24 +762,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 00:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 40 N NCS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell -\pard\intbl\qc\fs16 -4 \cell -\pard\intbl\qc\fs16 <35 - 115 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 132.60 N CS \cell +\pard\intbl\qc\fs16 L3 (>=3x baseline umol/L) \cell +\pard\intbl\qc\fs16 0.00 \cell +\pard\intbl\qc\fs16 71 - <141 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -734,24 +790,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11JUL2013 / 00:00 (-8) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 44 N NCS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 132.60 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0.00 \cell +\pard\intbl\qc\fs16 71 - <141 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 <35 - <115 \cell \row } @@ -760,24 +818,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Alkaline Phosphatase (U/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 67 N NCS \cell +\pard\intbl\qc\fs16 L3 (>3x ULN Enzyme U/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 00:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 38 N NCS \cell -\pard\intbl\qc\fs16 L1 (>2.620 mmol/L) \cell -\pard\intbl\qc\fs16 -6 \cell -\pard\intbl\qc\fs16 35 - 115 \cell +\pard\intbl\qc\fs16 35 - <115 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -786,24 +846,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 00:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 40 N NCS \cell -\pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs16 -4 \cell -\pard\intbl\qc\fs16 <35 - <115 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 89 N CS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 22 \cell +\pard\intbl\qc\fs16 35 - <115 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -812,24 +874,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 00:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 40 N CS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 -4 \cell -\pard\intbl\qc\fs16 35 - 115 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 76 N NCS \cell +\pard\intbl\qc\fs16 L2 (>2x ULN Enzyme U/L) \cell +\pard\intbl\qc\fs16 9 \cell +\pard\intbl\qc\fs16 <35 - 115 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -838,23 +902,25 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Anisocytes \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 1 NCS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell +\pard\intbl\qc\fs16 Aspartate Aminotransferase (U/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 20 N CS \cell +\pard\intbl\qc\fs16 L3 (>10x ULN Enzyme U/L) \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 11 - <36 \cell \pard\intbl\qc\fs16 \cell \row } @@ -864,23 +930,25 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 1 NCS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 26 N NCS \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 <11 - 36 \cell \pard\intbl\qc\fs16 \cell \row } @@ -890,24 +958,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Aspartate Aminotransferase (U/L) \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 23 N NCS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell -\pard\intbl\qc\fs16 -1 \cell -\pard\intbl\qc\fs16 <11 - 36 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 20 N CS \cell +\pard\intbl\qc\fs16 L2 (>5x ULN Enzyme U/L) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 11 - 36 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -916,24 +986,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 4.9393 N CS \cell +\pard\intbl\qc\fs16 L3 (>7.758 mmol/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 21 N NCS \cell -\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell -\pard\intbl\qc\fs16 -3 \cell -\pard\intbl\qc\fs16 <11 - <36 \cell +\pard\intbl\qc\fs16 <3.85 - <7.4 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -942,24 +1014,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 23 N NCS \cell -\pard\intbl\qc\fs16 L1 (>2.620 mmol/L) \cell -\pard\intbl\qc\fs16 -1 \cell -\pard\intbl\qc\fs16 <11 - 36 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 5.0944 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0.1552 \cell +\pard\intbl\qc\fs16 3.85 - 7.4 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -968,24 +1042,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 18 N NCS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 -6 \cell -\pard\intbl\qc\fs16 <11 - <36 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 5.0944 N NCS \cell +\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell +\pard\intbl\qc\fs16 0.1552 \cell +\pard\intbl\qc\fs16 <3.85 - 7.4 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -994,24 +1070,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 00:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 28 N NCS \cell -\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell -\pard\intbl\qc\fs16 4 \cell -\pard\intbl\qc\fs16 <11 - <36 \cell +\pard\intbl\qc\fs16 HDL Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 2.1243 N NCS \cell +\pard\intbl\qc\fs16 L3 (<0.517 mmol/L) \cell +\pard\intbl\qc\fs16 0.0000 \cell +\pard\intbl\qc\fs16 0.37 - <0.51 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1020,24 +1098,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 00:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 28 N NCS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 4 \cell -\pard\intbl\qc\fs16 11 - 36 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 1.6668 N NCS \cell +\pard\intbl\qc\fs16 L1 (<1.034 mmol/L) \cell +\pard\intbl\qc\fs16 -0.4574 \cell +\pard\intbl\qc\fs16 <0.37 - <0.51 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1046,24 +1126,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11JUL2013 / 00:00 (-8) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 24 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.5x ULN Enzyme U/L) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11 - 36 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 1.5897 N CS \cell +\pard\intbl\qc\fs16 L3 (<0.517 mmol/L) \cell +\pard\intbl\qc\fs16 -0.5345 \cell +\pard\intbl\qc\fs16 <0.37 - 0.51 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1072,24 +1154,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 LDL Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 1.9497 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0.0000 \cell +\pard\intbl\qc\fs16 <1.4 - 8.6 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 00:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 24 N NCS \cell -\pard\intbl\qc\fs16 L1 (>10.8 10^9/L) \cell -\pard\intbl\qc\fs16 0 \cell -\pard\intbl\qc\fs16 <11 - <36 \cell \row } @@ -1098,24 +1182,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 00:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 24 N NCS \cell -\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell -\pard\intbl\qc\fs16 0 \cell -\pard\intbl\qc\fs16 <11 - <36 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 1.6580 N CS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 -0.2917 \cell +\pard\intbl\qc\fs16 1.4 - <8.6 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1124,24 +1210,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 00:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 26 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.5x ULN Enzyme U/L) \cell -\pard\intbl\qc\fs16 2 \cell -\pard\intbl\qc\fs16 11 - <36 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.3768 N NCS \cell +\pard\intbl\qc\fs16 L2 (>4.138 mmol/L) \cell +\pard\intbl\qc\fs16 0.4271 \cell +\pard\intbl\qc\fs16 1.4 - 8.6 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1150,24 +1238,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Basophils Abs (10^9/L) \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0.06 N CS \cell -\pard\intbl\qc\fs16 L1 (>10.8 10^9/L) \cell -\pard\intbl\qc\fs16 -1.46 \cell -\pard\intbl\qc\fs16 <0 - 0.2 \cell +\pard\intbl\qc\fs16 Triglycerides (mmol/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 2.0094 NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0.0000 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1176,24 +1266,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0.04 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.694 mmol/L) \cell -\pard\intbl\qc\fs16 -1.48 \cell -\pard\intbl\qc\fs16 <0 - <0.2 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 4.5887 NCS \cell +\pard\intbl\qc\fs16 L3 (>5.645 mmol/L) \cell +\pard\intbl\qc\fs16 2.5793 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1202,24 +1294,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0.05 N CS \cell -\pard\intbl\qc\fs16 L3 (>6.5 mmol/L) \cell -\pard\intbl\qc\fs16 -1.47 \cell -\pard\intbl\qc\fs16 <0 - 0.2 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.9683 N CS \cell +\pard\intbl\qc\fs16 L1 (>1.694 mmol/L) \cell +\pard\intbl\qc\fs16 0.9589 \cell +\pard\intbl\qc\fs16 0.8 - 3 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1228,24 +1322,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Hemoglobin (g/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 9.9917 N NCS \cell +\pard\intbl\qc\fs16 L1 (125-135 g/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 00:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0.07 N NCS \cell -\pard\intbl\qc\fs16 L2 (>6.0 mmol/L) \cell -\pard\intbl\qc\fs16 -1.45 \cell -\pard\intbl\qc\fs16 0 - <0.2 \cell +\pard\intbl\qc\fs16 7.76 - 10.55 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1254,24 +1350,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 00:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0.04 N NCS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell -\pard\intbl\qc\fs16 -1.48 \cell -\pard\intbl\qc\fs16 0 - 0.2 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 10.1778 N CS \cell +\pard\intbl\qc\fs16 L1 (125-135 g/L) \cell +\pard\intbl\qc\fs16 0.1862 \cell +\pard\intbl\qc\fs16 <7.76 - 10.55 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1280,24 +1378,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 00:00 (27) \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell \pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0.04 N NCS \cell -\pard\intbl\qc\fs16 L2 (>13.0 10^9/L) \cell -\pard\intbl\qc\fs16 -1.48 \cell -\pard\intbl\qc\fs16 0 - 0.2 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 10.0537 N NCS \cell +\pard\intbl\qc\fs16 L2 (<125 g/L) \cell +\pard\intbl\qc\fs16 0.0621 \cell +\pard\intbl\qc\fs16 7.76 - <10.55 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1306,24 +1406,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Leukocytes (10^9/L) \cell +\pard\intbl\qc\fs16 10MAR2014 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 9.53 N CS \cell +\pard\intbl\qc\fs16 L3 (<1.0 10^9/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 00:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0.06 N NCS \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 -1.46 \cell -\pard\intbl\qc\fs16 <0 - <0.2 \cell +\pard\intbl\qc\fs16 3.8 - <10.7 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1332,24 +1434,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 00:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0.04 N NCS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell -\pard\intbl\qc\fs16 -1.48 \cell -\pard\intbl\qc\fs16 0 - <0.2 \cell +\pard\intbl\qc\fs16 01APR2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 8.13 N CS \cell +\pard\intbl\qc\fs16 L3 (>15.0 10^9/L) \cell +\pard\intbl\qc\fs16 -1.40 \cell +\pard\intbl\qc\fs16 <3.8 - 10.7 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1358,24 +1462,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Basophils/Leukocytes (FRACTION) \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0.40 H CS \cell -\pard\intbl\qc\fs16 L2 (>13.0 10^9/L) \cell -\pard\intbl\qc\fs16 0.10 \cell -\pard\intbl\qc\fs16 <0 - 0.02 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 8.20 N CS \cell +\pard\intbl\qc\fs16 L3 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs16 -1.33 \cell +\pard\intbl\qc\fs16 <3.8 - <10.7 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1384,24 +1490,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Eosinophils (10^9/L) \cell +\pard\intbl\qc\fs16 14APR2014 / 00:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 0.16 N NCS \cell +\pard\intbl\qc\fs16 L3 (>5.0 10^9/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11JUL2013 / 00:00 (-8) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0.30 H NCS \cell -\pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell +\pard\intbl\qc\fs16 <0 - 0.57 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 0 - 0.02 \cell \row } @@ -1410,24 +1518,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Calcium (mmol/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 2.2205 N NCS \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Bilirubin (umol/L) \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 11.97 N CS \cell -\pard\intbl\qc\fs16 L2 (>13.0 10^9/L) \cell -\pard\intbl\qc\fs16 -6.84 \cell -\pard\intbl\qc\fs16 <3 - <21 \cell +\pard\intbl\qc\fs16 2.1 - 2.57 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1436,24 +1546,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 13.68 N NCS \cell -\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell -\pard\intbl\qc\fs16 -5.13 \cell -\pard\intbl\qc\fs16 <3 - 21 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.2954 N NCS \cell +\pard\intbl\qc\fs16 L3 (<1.871 mmol/L) \cell +\pard\intbl\qc\fs16 0.0749 \cell +\pard\intbl\qc\fs16 <2.1 - 2.57 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1462,24 +1574,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Chloride (mmol/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 105 N CS \cell +\pard\intbl\qc\fs16 L3 (<80 mmol/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 15.39 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.5x ULN Enzyme U/L) \cell -\pard\intbl\qc\fs16 -3.42 \cell -\pard\intbl\qc\fs16 3 - <21 \cell +\pard\intbl\qc\fs16 <94 - <112 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1488,24 +1602,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 11.97 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.694 mmol/L) \cell -\pard\intbl\qc\fs16 -6.84 \cell -\pard\intbl\qc\fs16 3 - 21 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 105 N NCS \cell +\pard\intbl\qc\fs16 L2 (<88 mmol/L) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 94 - 112 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1514,24 +1630,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Creatinine Kinase (U/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 60 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 21 - <169 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 00:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 13.68 N NCS \cell -\pard\intbl\qc\fs16 L2 (fasting >=6.99 mmol/L or random >=11.10 mmol/L) \cell -\pard\intbl\qc\fs16 -5.13 \cell -\pard\intbl\qc\fs16 <3 - 21 \cell \row } @@ -1540,24 +1658,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 00:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 13.68 N NCS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell -\pard\intbl\qc\fs16 -5.13 \cell -\pard\intbl\qc\fs16 3 - 21 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 72 N NCS \cell +\pard\intbl\qc\fs16 L2 (>5x ULN Enzyme U/L) \cell +\pard\intbl\qc\fs16 12 \cell +\pard\intbl\qc\fs16 <21 - 169 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1566,24 +1686,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11JUL2013 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Glucose (mmol/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell \pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 18.81 N NCS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 5.3290 N NCS \cell +\pard\intbl\qc\fs16 L2 (<3.00 mmol/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 <3 - 21 \cell +\pard\intbl\qc\fs16 <2.8 - 13.9 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1592,24 +1714,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 00:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 13.68 N CS \cell -\pard\intbl\qc\fs16 L1 (125-135 g/L) \cell -\pard\intbl\qc\fs16 -5.13 \cell -\pard\intbl\qc\fs16 3 - <21 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 5.3290 N CS \cell +\pard\intbl\qc\fs16 L1 (<3.89 mmol/L) \cell +\pard\intbl\qc\fs16 0.0000 \cell +\pard\intbl\qc\fs16 <2.8 - <13.9 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1618,24 +1742,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Phosphate (mmol/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 1.0010 N NCS \cell +\pard\intbl\qc\fs16 L2 (<0.646 mmol/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 00:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 13.68 N CS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 -5.13 \cell -\pard\intbl\qc\fs16 3 - <21 \cell +\pard\intbl\qc\fs16 0.71 - 1.65 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1644,24 +1770,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 00:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 11.97 N NCS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell -\pard\intbl\qc\fs16 -6.84 \cell -\pard\intbl\qc\fs16 3 - <21 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 1.0656 N CS \cell +\pard\intbl\qc\fs16 L1 (<0.807 mmol/L) \cell +\pard\intbl\qc\fs16 0.0646 \cell +\pard\intbl\qc\fs16 <0.71 - 1.65 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1670,24 +1798,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium (mmol/L) \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2.2205 N NCS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 -0.0749 \cell -\pard\intbl\qc\fs16 2.1 - 2.57 \cell +\pard\intbl\qc\fs16 Potassium (mmol/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 3.9 N CS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <3.4 - 5.4 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -1696,24 +1826,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2.1207 N NCS \cell -\pard\intbl\qc\fs16 L2 (>2.745 mmol/L) \cell -\pard\intbl\qc\fs16 -0.1747 \cell -\pard\intbl\qc\fs16 <2.1 - 2.57 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 4.7 N CS \cell +\pard\intbl\qc\fs16 L3 (>6.5 mmol/L) \cell +\pard\intbl\qc\fs16 0.8 \cell +\pard\intbl\qc\fs16 <3.4 - <5.4 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1722,24 +1854,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Sodium (mmol/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 137 N NCS \cell +\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2.0958 L NCS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 -0.1996 \cell -\pard\intbl\qc\fs16 2.1 - 2.57 \cell +\pard\intbl\qc\fs16 <135 - <145 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1748,24 +1882,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 1.9960 L NCS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 -0.2994 \cell -\pard\intbl\qc\fs16 <2.1 - 2.57 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 138 N CS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 <135 - 145 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1774,24 +1910,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Alanine Aminotransferase (U/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 23 N CS \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 00:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2.2205 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.694 mmol/L) \cell -\pard\intbl\qc\fs16 -0.0749 \cell -\pard\intbl\qc\fs16 <2.1 - 2.57 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <6 - 32 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1800,24 +1938,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 00:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2.1457 N CS \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 19 N CS \cell +\pard\intbl\qc\fs16 L2 (>5x ULN Enzyme U/L) \cell +\pard\intbl\qc\fs16 -4 \cell +\pard\intbl\qc\fs16 <6 - 32 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 -0.1497 \cell -\pard\intbl\qc\fs16 2.1 - <2.57 \cell \row } @@ -1826,24 +1966,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11JUL2013 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Alkaline Phosphatase (U/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell \pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2.2954 N CS \cell -\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 64 N NCS \cell +\pard\intbl\qc\fs16 L1 (>1.5x ULN Enzyme U/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2.1 - <2.57 \cell +\pard\intbl\qc\fs16 <35 - 115 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1852,24 +1994,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 00:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2.1706 N NCS \cell -\pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs16 -0.1248 \cell -\pard\intbl\qc\fs16 2.1 - <2.57 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 58 N NCS \cell +\pard\intbl\qc\fs16 L2 (>2x ULN Enzyme U/L) \cell +\pard\intbl\qc\fs16 -6 \cell +\pard\intbl\qc\fs16 <35 - <115 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1878,24 +2022,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Bilirubin (umol/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 6.84 N CS \cell +\pard\intbl\qc\fs16 L1 (>1.5x ULN umol/L) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 <3 - <21 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 00:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2.2205 N CS \cell -\pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs16 -0.0749 \cell -\pard\intbl\qc\fs16 <2.1 - 2.57 \cell \row } @@ -1904,24 +2050,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 00:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2.1956 N NCS \cell -\pard\intbl\qc\fs16 L2 (>2.745 mmol/L) \cell -\pard\intbl\qc\fs16 -0.0998 \cell -\pard\intbl\qc\fs16 <2.1 - 2.57 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 8.55 N CS \cell +\pard\intbl\qc\fs16 L3 (>3x ULN umol/L) \cell +\pard\intbl\qc\fs16 1.71 \cell +\pard\intbl\qc\fs16 <3 - <21 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1930,24 +2078,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Chloride (mmol/L) \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 103 N NCS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 0 \cell -\pard\intbl\qc\fs16 <94 - 112 \cell +\pard\intbl\qc\fs16 Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 5.7151 N CS \cell +\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4.03 - 7.76 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1956,24 +2106,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 105 N NCS \cell -\pard\intbl\qc\fs16 L2 (>6.0 mmol/L) \cell -\pard\intbl\qc\fs16 2 \cell -\pard\intbl\qc\fs16 <94 - 112 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 5.4565 N CS \cell +\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell +\pard\intbl\qc\fs16 -0.2586 \cell +\pard\intbl\qc\fs16 <4.03 - 7.76 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -1982,24 +2134,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 HDL Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 0.9806 N NCS \cell +\pard\intbl\qc\fs16 L3 (<0.517 mmol/L) \cell +\pard\intbl\qc\fs16 0.0000 \cell +\pard\intbl\qc\fs16 <0.34 - 0.48 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 107 N NCS \cell -\pard\intbl\qc\fs16 L2 (>6.0 mmol/L) \cell -\pard\intbl\qc\fs16 4 \cell -\pard\intbl\qc\fs16 <94 - 112 \cell \row } @@ -2008,24 +2162,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 108 N CS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 5 \cell -\pard\intbl\qc\fs16 <94 - <112 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 1.4462 N CS \cell +\pard\intbl\qc\fs16 L2 (<1.034 mmol/L) \cell +\pard\intbl\qc\fs16 0.4656 \cell +\pard\intbl\qc\fs16 0.34 - 0.48 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2034,24 +2190,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Triglycerides (mmol/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 2.9368 N CS \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 00:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 105 N NCS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 2 \cell -\pard\intbl\qc\fs16 94 - <112 \cell +\pard\intbl\qc\fs16 0.0000 \cell +\pard\intbl\qc\fs16 0.8 - 3 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2060,24 +2218,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 00:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 105 N NCS \cell -\pard\intbl\qc\fs16 L1 (125-135 g/L) \cell -\pard\intbl\qc\fs16 2 \cell -\pard\intbl\qc\fs16 <94 - 112 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 1.9556 N NCS \cell +\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell +\pard\intbl\qc\fs16 -0.9812 \cell +\pard\intbl\qc\fs16 0.8 - <3 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2086,24 +2246,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11JUL2013 / 00:00 (-8) \cell +\pard\intbl\qc\fs16 Hemoglobin (g/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell \pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 103 N NCS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 7.4472 N CS \cell +\pard\intbl\qc\fs16 L3 (<95 g/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 94 - <112 \cell +\pard\intbl\qc\fs16 <7.14 - <9.81 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2112,24 +2274,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 00:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 111 N NCS \cell -\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell -\pard\intbl\qc\fs16 8 \cell -\pard\intbl\qc\fs16 <94 - <112 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 7.5713 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0.1241 \cell +\pard\intbl\qc\fs16 7.14 - 9.81 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2138,24 +2302,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Leukocytes (10^9/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 4.59 N NCS \cell +\pard\intbl\qc\fs16 L3 (<1.0 10^9/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 00:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 103 N NCS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 0 \cell -\pard\intbl\qc\fs16 94 - <112 \cell +\pard\intbl\qc\fs16 3.8 - 10.7 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2164,24 +2330,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 00:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 107 N NCS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 4 \cell -\pard\intbl\qc\fs16 94 - 112 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 6.55 N CS \cell +\pard\intbl\qc\fs16 L2 (<3.0 10^9/L) \cell +\pard\intbl\qc\fs16 1.96 \cell +\pard\intbl\qc\fs16 <3.8 - <10.7 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2190,24 +2358,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Cholesterol (mmol/L) \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 4.7065 N NCS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 -0.1034 \cell -\pard\intbl\qc\fs16 <3.85 - <7.4 \cell +\pard\intbl\qc\fs16 Platelets (10^9/L) \cell +\pard\intbl\qc\fs16 25AUG2012 / 00:00 (-13) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 255 N NCS \cell +\pard\intbl\qc\fs16 L2 (<125 10^9/L) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 130 - <394 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2216,24 +2386,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 4.3962 N CS \cell -\pard\intbl\qc\fs16 L1 (>1.5x ULN Enzyme U/L) \cell -\pard\intbl\qc\fs16 -0.4138 \cell -\pard\intbl\qc\fs16 3.85 - 7.4 \cell +\pard\intbl\qc\fs16 17SEP2012 / 00:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 195 N NCS \cell +\pard\intbl\qc\fs16 L1 (<140 10^9/L) \cell +\pard\intbl\qc\fs16 -60 \cell +\pard\intbl\qc\fs16 130 - 394 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2242,24 +2414,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Albumin (g/L) \cell +\pard\intbl\qc\fs16 23NOV2012 / 00:00 (-7) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 39 N NCS \cell +\pard\intbl\qc\fs16 L2 (<25.0 g/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 4.2410 N NCS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell -\pard\intbl\qc\fs16 -0.5689 \cell -\pard\intbl\qc\fs16 <3.85 - <7.4 \cell +\pard\intbl\qc\fs16 35 - 46 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2268,24 +2442,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 3.9307 N NCS \cell -\pard\intbl\qc\fs16 L1 (125-135 g/L) \cell -\pard\intbl\qc\fs16 -0.8792 \cell -\pard\intbl\qc\fs16 <3.85 - <7.4 \cell +\pard\intbl\qc\fs16 13DEC2012 / 00:00 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 36 N CS \cell +\pard\intbl\qc\fs16 L3 (<20.0 g/L) \cell +\pard\intbl\qc\fs16 -3 \cell +\pard\intbl\qc\fs16 35 - <46 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2294,24 +2470,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 00:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 5.0686 N CS \cell -\pard\intbl\qc\fs16 L2 (>6.0 mmol/L) \cell -\pard\intbl\qc\fs16 0.2586 \cell -\pard\intbl\qc\fs16 3.85 - 7.4 \cell +\pard\intbl\qc\fs16 26DEC2012 / 00:00 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 35 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 -4 \cell +\pard\intbl\qc\fs16 <35 - 46 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2320,24 +2498,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 00:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 4.4221 N NCS \cell -\pard\intbl\qc\fs16 L2 (>13.0 10^9/L) \cell -\pard\intbl\qc\fs16 -0.3879 \cell -\pard\intbl\qc\fs16 3.85 - 7.4 \cell +\pard\intbl\qc\fs16 26DEC2012 / 00:00 (27) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 35 N CS \cell +\pard\intbl\qc\fs16 L3 (<20.0 g/L) \cell +\pard\intbl\qc\fs16 -4 \cell +\pard\intbl\qc\fs16 35 - 46 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2346,24 +2526,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11JUL2013 / 00:00 (-8) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 4.8100 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.694 mmol/L) \cell +\pard\intbl\qc\fs16 28DEC2012 / 00:00 (29) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3.85 - 7.4 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 37 N NCS \cell +\pard\intbl\qc\fs16 L2 (<25.0 g/L) \cell +\pard\intbl\qc\fs16 -2 \cell +\pard\intbl\qc\fs16 <35 - <46 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2372,24 +2554,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 00:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 4.3703 N CS \cell -\pard\intbl\qc\fs16 L2 (>3.387 mmol/L) \cell -\pard\intbl\qc\fs16 -0.4396 \cell -\pard\intbl\qc\fs16 3.85 - 7.4 \cell +\pard\intbl\qc\fs16 10JAN2013 / 00:00 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 37 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 -2 \cell +\pard\intbl\qc\fs16 <35 - <46 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2398,24 +2582,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 00:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 4.6807 N NCS \cell -\pard\intbl\qc\fs16 L3 (>15.0 10^9/L) \cell -\pard\intbl\qc\fs16 -0.1293 \cell -\pard\intbl\qc\fs16 3.85 - 7.4 \cell +\pard\intbl\qc\fs16 23JAN2013 / 00:00 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 39 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 35 - 46 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2424,24 +2610,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 00:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 4.2669 N NCS \cell -\pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs16 -0.5431 \cell -\pard\intbl\qc\fs16 <3.85 - 7.4 \cell +\pard\intbl\qc\fs16 23JAN2013 / 00:00 (55) \cell +\pard\intbl\qc\fs16 Post-baseline last \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 39 N NCS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 <35 - 46 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2450,23 +2638,25 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Color \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 L2 (>13.0 10^9/L) \cell +\pard\intbl\qc\fs16 23JAN2013 / 00:00 (55) \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 39 N CS \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 35 - <46 \cell \pard\intbl\qc\fs16 \cell \row } @@ -2476,24 +2666,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Calcium (mmol/L) \cell +\pard\intbl\qc\fs16 23NOV2012 / 00:00 (-7) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 2.2704 N NCS \cell +\pard\intbl\qc\fs16 L3 (<1.871 mmol/L) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2.1 - 2.57 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2502,24 +2694,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 00:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 L1 (>1.5x ULN Enzyme U/L) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 13DEC2012 / 00:00 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.2205 N NCS \cell +\pard\intbl\qc\fs16 L2 (<1.996 mmol/L) \cell +\pard\intbl\qc\fs16 -0.0499 \cell +\pard\intbl\qc\fs16 2.1 - <2.57 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2528,24 +2722,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11JUL2013 / 00:00 (-8) \cell -\pard\intbl\qc\fs16 Baseline \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 L2 (fasting >=6.99 mmol/L or random >=11.10 mmol/L) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 13DEC2012 / 00:00 (14) \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.2205 N NCS \cell +\pard\intbl\qc\fs16 L3 (<1.871 mmol/L) \cell +\pard\intbl\qc\fs16 -0.0499 \cell +\pard\intbl\qc\fs16 2.1 - 2.57 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2554,24 +2750,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Creatinine (umol/L) \cell -\pard\intbl\qc\fs16 01AUG2013 / 00:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 132.60 N NCS \cell -\pard\intbl\qc\fs16 L1 (>1.694 mmol/L) \cell -\pard\intbl\qc\fs16 8.84 \cell -\pard\intbl\qc\fs16 71 - <141 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26DEC2012 / 00:00 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.2954 N NCS \cell +\pard\intbl\qc\fs16 L1 (<2.096 mmol/L) \cell +\pard\intbl\qc\fs16 0.0250 \cell +\pard\intbl\qc\fs16 2.1 - 2.57 \cell +\pard\intbl\qc\fs16 \cell \row } @@ -2580,24 +2778,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 00:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 123.76 N NCS \cell -\pard\intbl\qc\fs16 L1 (>5.172 mmol/L) \cell -\pard\intbl\qc\fs16 0.00 \cell -\pard\intbl\qc\fs16 71 - <141 \cell +\pard\intbl\qc\fs16 28DEC2012 / 00:00 (29) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.3952 N NCS \cell +\pard\intbl\qc\fs16 L3 (<1.871 mmol/L) \cell +\pard\intbl\qc\fs16 0.1248 \cell +\pard\intbl\qc\fs16 <2.1 - <2.57 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2606,24 +2806,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 00:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 132.60 N NCS \cell -\pard\intbl\qc\fs16 L1 (<132 mmol/L) \cell -\pard\intbl\qc\fs16 8.84 \cell -\pard\intbl\qc\fs16 71 - <141 \cell +\pard\intbl\qc\fs16 28DEC2012 / 00:00 (29) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.3952 N NCS \cell +\pard\intbl\qc\fs16 L3 (<1.871 mmol/L) \cell +\pard\intbl\qc\fs16 0.1248 \cell +\pard\intbl\qc\fs16 2.1 - <2.57 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2632,24 +2834,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3967 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5749 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6551 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3655 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6997 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7666 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8200 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11231 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8780 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9448 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10429 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11097 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 00:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 114.92 N CS \cell -\pard\intbl\qc\fs16 L2 (>6.206 mmol/L) \cell -\pard\intbl\qc\fs16 -8.84 \cell -\pard\intbl\qc\fs16 71 - 141 \cell +\pard\intbl\qc\fs16 10JAN2013 / 00:00 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 AFTER TREATMENT \cell +\pard\intbl\qc\fs16 2.2954 N NCS \cell +\pard\intbl\qc\fs16 L2 (>2.745 mmol/L) \cell +\pard\intbl\qc\fs16 0.0250 \cell +\pard\intbl\qc\fs16 <2.1 - <2.57 \cell +\pard\intbl\qc\fs16 Yes \cell \row } @@ -2658,12 +2862,13 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3967 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5749 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6551 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3655 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6997 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7666 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8200 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11231 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8780 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9448 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10429 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11097 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11899 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2676,6 +2881,7 @@ \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } @@ -2684,12 +2890,13 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3967 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5749 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6551 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3655 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8200 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11231 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8780 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9448 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11097 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell @@ -2702,6 +2909,7 @@ \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } \par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} diff --git a/tests/testthat/_snaps/lsflab02/lsflab02.rtf b/tests/testthat/_snaps/lsflab02/lsflab02.rtf new file mode 100644 index 00000000..0ac85b4a --- /dev/null +++ b/tests/testthat/_snaps/lsflab02/lsflab02.rtf @@ -0,0 +1,1940 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx940 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2639 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4920 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8184 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9168 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10018 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10868 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11717 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSFLAB02:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx940 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2639 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4920 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8184 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9168 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10018 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10868 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11717 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell +\pard\intbl\qc\fs16 \keepn\trhdr Assessment Date (Study Day\super a\nosupersub ) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Visit \cell +\pard\intbl\qc\fs16 \keepn\trhdr ALT\line(x ULN) \cell +\pard\intbl\qc\fs16 \keepn\trhdr AST\line(x ULN) \cell +\pard\intbl\qc\fs16 \keepn\trhdr ALP\line(x ULN) \cell +\pard\intbl\qc\fs16 \keepn\trhdr TBILI\line(x ULN) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell +\pard\intbl\qc\fs16 23NOV2012 (-7) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 4.14 \cell +\pard\intbl\qc\fs16 4.14 \cell +\pard\intbl\qc\fs16 0.81* \cell +\pard\intbl\qc\fs16 3.03 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 13DEC2012 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 4.14 \cell +\pard\intbl\qc\fs16 4.14 \cell +\pard\intbl\qc\fs16 0.77 \cell +\pard\intbl\qc\fs16 3.03^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26DEC2012 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 4.14 \cell +\pard\intbl\qc\fs16 4.14 \cell +\pard\intbl\qc\fs16 0.79* \cell +\pard\intbl\qc\fs16 3.03^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 28DEC2012 (29) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4.14* \cell +\pard\intbl\qc\fs16 4.14 \cell +\pard\intbl\qc\fs16 0.88 \cell +\pard\intbl\qc\fs16 3.03^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 10JAN2013 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 4.14* \cell +\pard\intbl\qc\fs16 4.14 \cell +\pard\intbl\qc\fs16 0.85 \cell +\pard\intbl\qc\fs16 3.03^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23JAN2013 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 4.14 \cell +\pard\intbl\qc\fs16 4.14 \cell +\pard\intbl\qc\fs16 0.85 \cell +\pard\intbl\qc\fs16 3.03^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1028 \cell +\pard\intbl\qc\fs16 71 / Male / Asian \cell +\pard\intbl\qc\fs16 11JUL2013 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.38 \cell +\pard\intbl\qc\fs16 3.07* \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01AUG2013 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.40 \cell +\pard\intbl\qc\fs16 3.07*^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14AUG2013 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.33 \cell +\pard\intbl\qc\fs16 3.07*^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 29AUG2013 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.35 \cell +\pard\intbl\qc\fs16 3.07*^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 10SEP2013 (54) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.35 \cell +\pard\intbl\qc\fs16 3.07^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 09OCT2013 (83) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.36 \cell +\pard\intbl\qc\fs16 3.07^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 06NOV2013 (111) \cell +\pard\intbl\qc\fs16 Cycle 16 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.31 \cell +\pard\intbl\qc\fs16 3.07*^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 04DEC2013 (139) \cell +\pard\intbl\qc\fs16 Cycle 20 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11* \cell +\pard\intbl\qc\fs16 0.37 \cell +\pard\intbl\qc\fs16 3.07^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 06JAN2014 (172) \cell +\pard\intbl\qc\fs16 Cycle 24 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11* \cell +\pard\intbl\qc\fs16 0.41 \cell +\pard\intbl\qc\fs16 3.07^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14JAN2014 (180) \cell +\pard\intbl\qc\fs16 End Of Treatment \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11* \cell +\pard\intbl\qc\fs16 0.35 \cell +\pard\intbl\qc\fs16 3.07^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1034 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell +\pard\intbl\qc\fs16 24JUN2014 (-7) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11* \cell +\pard\intbl\qc\fs16 0.36* \cell +\pard\intbl\qc\fs16 3.17 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15JUL2014 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.30 \cell +\pard\intbl\qc\fs16 3.17^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 29JUL2014 (29) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.31 \cell +\pard\intbl\qc\fs16 3.17*^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 11AUG2014 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.29 \cell +\pard\intbl\qc\fs16 3.17^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26AUG2014 (57) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.25 \cell +\pard\intbl\qc\fs16 3.17^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 25SEP2014 (87) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.30 \cell +\pard\intbl\qc\fs16 3.17^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 21OCT2014 (113) \cell +\pard\intbl\qc\fs16 Cycle 16 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.30 \cell +\pard\intbl\qc\fs16 3.17^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 18NOV2014 (141) \cell +\pard\intbl\qc\fs16 Cycle 20 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.27 \cell +\pard\intbl\qc\fs16 3.17^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 17DEC2014 (170) \cell +\pard\intbl\qc\fs16 Cycle 24 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.35* \cell +\pard\intbl\qc\fs16 3.17*^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 30DEC2014 (183) \cell +\pard\intbl\qc\fs16 End Of Treatment \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 4.11 \cell +\pard\intbl\qc\fs16 0.23 \cell +\pard\intbl\qc\fs16 3.17^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1295 \cell +\pard\intbl\qc\fs16 88 / Female / Other \cell +\pard\intbl\qc\fs16 24OCT2013 (-28) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0.38 \cell +\pard\intbl\qc\fs16 0.62 \cell +\pard\intbl\qc\fs16 3.36 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 04NOV2013 (-17) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 0.44 \cell +\pard\intbl\qc\fs16 0.65 \cell +\pard\intbl\qc\fs16 3.46 \cell +\pard\intbl\qc\fs16 0.41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 05DEC2013 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0.59 \cell +\pard\intbl\qc\fs16 0.59 \cell +\pard\intbl\qc\fs16 3.39 \cell +\pard\intbl\qc\fs16 0.49* \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 18DEC2013 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 0.66 \cell +\pard\intbl\qc\fs16 0.76 \cell +\pard\intbl\qc\fs16 3.32* \cell +\pard\intbl\qc\fs16 0.49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01JAN2014 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 0.44 \cell +\pard\intbl\qc\fs16 0.59 \cell +\pard\intbl\qc\fs16 3.29* \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15JAN2014 (56) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 0.41* \cell +\pard\intbl\qc\fs16 0.56* \cell +\pard\intbl\qc\fs16 3.23 \cell +\pard\intbl\qc\fs16 0.49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 18FEB2014 (90) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 0.47 \cell +\pard\intbl\qc\fs16 0.56 \cell +\pard\intbl\qc\fs16 3.26* \cell +\pard\intbl\qc\fs16 0.41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 13MAR2014 (113) \cell +\pard\intbl\qc\fs16 Cycle 16 \cell +\pard\intbl\qc\fs16 0.59 \cell +\pard\intbl\qc\fs16 0.76 \cell +\pard\intbl\qc\fs16 3.30 \cell +\pard\intbl\qc\fs16 0.41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 19MAY2014 (180) \cell +\pard\intbl\qc\fs16 Cycle 20 \cell +\pard\intbl\qc\fs16 0.31 \cell +\pard\intbl\qc\fs16 0.53 \cell +\pard\intbl\qc\fs16 3.14 \cell +\pard\intbl\qc\fs16 0.41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1029 \cell +\pard\intbl\qc\fs16 82 / Male / Other \cell +\pard\intbl\qc\fs16 10DEC2012 (-15) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 0.49 \cell +\pard\intbl\qc\fs16 0.50 \cell +\pard\intbl\qc\fs16 0.41 \cell +\pard\intbl\qc\fs16 1.14 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 09JAN2013 (16) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0.49 \cell +\pard\intbl\qc\fs16 0.50 \cell +\pard\intbl\qc\fs16 0.50 \cell +\pard\intbl\qc\fs16 1.14 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 21JAN2013 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 0.46* \cell +\pard\intbl\qc\fs16 0.50 \cell +\pard\intbl\qc\fs16 0.52 \cell +\pard\intbl\qc\fs16 1.47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 06FEB2013 (44) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 0.37 \cell +\pard\intbl\qc\fs16 0.50 \cell +\pard\intbl\qc\fs16 0.41 \cell +\pard\intbl\qc\fs16 1.38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 19FEB2013 (57) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 0.49 \cell +\pard\intbl\qc\fs16 0.53 \cell +\pard\intbl\qc\fs16 0.41 \cell +\pard\intbl\qc\fs16 1.38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 20MAR2013 (86) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 0.46 \cell +\pard\intbl\qc\fs16 0.56* \cell +\pard\intbl\qc\fs16 0.40 \cell +\pard\intbl\qc\fs16 1.30 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 16APR2013 (113) \cell +\pard\intbl\qc\fs16 Cycle 16 \cell +\pard\intbl\qc\fs16 0.37 \cell +\pard\intbl\qc\fs16 0.50* \cell +\pard\intbl\qc\fs16 0.45 \cell +\pard\intbl\qc\fs16 1.22* \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15MAY2013 (142) \cell +\pard\intbl\qc\fs16 Cycle 20 \cell +\pard\intbl\qc\fs16 0.43 \cell +\pard\intbl\qc\fs16 0.58* \cell +\pard\intbl\qc\fs16 0.44 \cell +\pard\intbl\qc\fs16 2.52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12JUN2013 (170) \cell +\pard\intbl\qc\fs16 Cycle 24 \cell +\pard\intbl\qc\fs16 0.40 \cell +\pard\intbl\qc\fs16 0.75 \cell +\pard\intbl\qc\fs16 0.38 \cell +\pard\intbl\qc\fs16 1.22 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26JUN2013 (184) \cell +\pard\intbl\qc\fs16 End Of Treatment \cell +\pard\intbl\qc\fs16 0.51 \cell +\pard\intbl\qc\fs16 0.50 \cell +\pard\intbl\qc\fs16 0.41 \cell +\pard\intbl\qc\fs16 1.22 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-701-1015 \cell +\pard\intbl\qc\fs16 63 / Female / Black or African American \cell +\pard\intbl\qc\fs16 26DEC2013 (-7) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 0.79 \cell +\pard\intbl\qc\fs16 1.18 \cell +\pard\intbl\qc\fs16 0.30 \cell +\pard\intbl\qc\fs16 0.49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 16JAN2014 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 1.21 \cell +\pard\intbl\qc\fs16 0.97 \cell +\pard\intbl\qc\fs16 6.00 \cell +\pard\intbl\qc\fs16 0.41* \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 30JAN2014 (29) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 0.53 \cell +\pard\intbl\qc\fs16 0.62 \cell +\pard\intbl\qc\fs16 6.00 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12FEB2014 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 0.76 \cell +\pard\intbl\qc\fs16 0.76* \cell +\pard\intbl\qc\fs16 6.00 \cell +\pard\intbl\qc\fs16 0.24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 05MAR2014 (63) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 0.65* \cell +\pard\intbl\qc\fs16 0.62* \cell +\pard\intbl\qc\fs16 6.00 \cell +\pard\intbl\qc\fs16 0.41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26MAR2014 (84) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 0.79 \cell +\pard\intbl\qc\fs16 0.65 \cell +\pard\intbl\qc\fs16 6.00 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 07MAY2014 (126) \cell +\pard\intbl\qc\fs16 Cycle 16 \cell +\pard\intbl\qc\fs16 0.50 \cell +\pard\intbl\qc\fs16 0.68* \cell +\pard\intbl\qc\fs16 6.00 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 21MAY2014 (140) \cell +\pard\intbl\qc\fs16 Cycle 20 \cell +\pard\intbl\qc\fs16 0.62 \cell +\pard\intbl\qc\fs16 0.56* \cell +\pard\intbl\qc\fs16 6.00 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 18JUN2014 (168) \cell +\pard\intbl\qc\fs16 Cycle 24 \cell +\pard\intbl\qc\fs16 0.68 \cell +\pard\intbl\qc\fs16 0.68 \cell +\pard\intbl\qc\fs16 6.00 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 02JUL2014 (182) \cell +\pard\intbl\qc\fs16 End Of Treatment \cell +\pard\intbl\qc\fs16 0.68 \cell +\pard\intbl\qc\fs16 0.56 \cell +\pard\intbl\qc\fs16 6.00 \cell +\pard\intbl\qc\fs16 0.24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1047 \cell +\pard\intbl\qc\fs16 85 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 22JAN2013 (-21) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 4.06 \cell +\pard\intbl\qc\fs16 4.06* \cell +\pard\intbl\qc\fs16 0.68 \cell +\pard\intbl\qc\fs16 3.07 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 25FEB2013 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 4.06* \cell +\pard\intbl\qc\fs16 4.06 \cell +\pard\intbl\qc\fs16 0.58 \cell +\pard\intbl\qc\fs16 3.07^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 10MAR2013 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 4.06 \cell +\pard\intbl\qc\fs16 4.06 \cell +\pard\intbl\qc\fs16 0.62 \cell +\pard\intbl\qc\fs16 3.07^ \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 07APR2013 (55) \cell +\pard\intbl\qc\fs16 Unscheduled 6.1 \cell +\pard\intbl\qc\fs16 4.06 \cell +\pard\intbl\qc\fs16 4.06 \cell +\pard\intbl\qc\fs16 0.65 \cell +\pard\intbl\qc\fs16 3.07 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1186 \cell +\pard\intbl\qc\fs16 84 / Female / Asian \cell +\pard\intbl\qc\fs16 03JAN2014 (-5) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 1.56 \cell +\pard\intbl\qc\fs16 1.59 \cell +\pard\intbl\qc\fs16 4.91 \cell +\pard\intbl\qc\fs16 1.22 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23JAN2014 (16) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 3.25 \cell +\pard\intbl\qc\fs16 3.47 \cell +\pard\intbl\qc\fs16 5.84* \cell +\pard\intbl\qc\fs16 5.54^# \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26JAN2014 (19) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2.97 \cell +\pard\intbl\qc\fs16 3.38 \cell +\pard\intbl\qc\fs16 5.23* \cell +\pard\intbl\qc\fs16 5.94^# \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 29JAN2014 (22) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 3.34 \cell +\pard\intbl\qc\fs16 3.97* \cell +\pard\intbl\qc\fs16 5.71 \cell +\pard\intbl\qc\fs16 5.94^# \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01FEB2014 (25) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2.88 \cell +\pard\intbl\qc\fs16 3.35 \cell +\pard\intbl\qc\fs16 5.66 \cell +\pard\intbl\qc\fs16 4.72^# \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 07FEB2014 (31) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2.28 \cell +\pard\intbl\qc\fs16 2.71 \cell +\pard\intbl\qc\fs16 5.97 \cell +\pard\intbl\qc\fs16 3.42^# \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1286 \cell +\pard\intbl\qc\fs16 80 / Female / Unknown \cell +\pard\intbl\qc\fs16 25AUG2013 (-16) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 0.41 \cell +\pard\intbl\qc\fs16 0.82 \cell +\pard\intbl\qc\fs16 0.59 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23SEP2013 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0.38 \cell +\pard\intbl\qc\fs16 0.71 \cell +\pard\intbl\qc\fs16 0.61 \cell +\pard\intbl\qc\fs16 0.24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 09OCT2013 (30) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0.51 \cell +\pard\intbl\qc\fs16 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 19OCT2013 (40) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 0.44* \cell +\pard\intbl\qc\fs16 0.91 \cell +\pard\intbl\qc\fs16 0.57 \cell +\pard\intbl\qc\fs16 0.33* \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 03NOV2013 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 0.38 \cell +\pard\intbl\qc\fs16 0.79 \cell +\pard\intbl\qc\fs16 0.58 \cell +\pard\intbl\qc\fs16 0.24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 29DEC2013 (111) \cell +\pard\intbl\qc\fs16 Cycle 16 \cell +\pard\intbl\qc\fs16 0.44 \cell +\pard\intbl\qc\fs16 0.79 \cell +\pard\intbl\qc\fs16 0.66 \cell +\pard\intbl\qc\fs16 0.41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01FEB2014 (145) \cell +\pard\intbl\qc\fs16 Cycle 20 \cell +\pard\intbl\qc\fs16 0.41 \cell +\pard\intbl\qc\fs16 0.82 \cell +\pard\intbl\qc\fs16 0.68* \cell +\pard\intbl\qc\fs16 0.24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23FEB2014 (167) \cell +\pard\intbl\qc\fs16 Cycle 24 \cell +\pard\intbl\qc\fs16 3.88 \cell +\pard\intbl\qc\fs16 4.94 \cell +\pard\intbl\qc\fs16 1.26 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 08MAR2014 (180) \cell +\pard\intbl\qc\fs16 End Of Treatment \cell +\pard\intbl\qc\fs16 0.69 \cell +\pard\intbl\qc\fs16 0.97 \cell +\pard\intbl\qc\fs16 0.83* \cell +\pard\intbl\qc\fs16 0.24* \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1339 \cell +\pard\intbl\qc\fs16 81 / Male / Black or African American \cell +\pard\intbl\qc\fs16 15DEC2012 (-8) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 0.71* \cell +\pard\intbl\qc\fs16 0.67 \cell +\pard\intbl\qc\fs16 0.74 \cell +\pard\intbl\qc\fs16 0.41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 05JAN2013 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0.77 \cell +\pard\intbl\qc\fs16 0.69 \cell +\pard\intbl\qc\fs16 0.65 \cell +\pard\intbl\qc\fs16 0.41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 20JAN2013 (29) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 0.74 \cell +\pard\intbl\qc\fs16 0.67 \cell +\pard\intbl\qc\fs16 0.71 \cell +\pard\intbl\qc\fs16 0.57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 03FEB2013 (43) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 0.89* \cell +\pard\intbl\qc\fs16 0.69 \cell +\pard\intbl\qc\fs16 0.66 \cell +\pard\intbl\qc\fs16 0.41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 19FEB2013 (59) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 0.77 \cell +\pard\intbl\qc\fs16 0.61 \cell +\pard\intbl\qc\fs16 0.65 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 17MAR2013 (85) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 0.71 \cell +\pard\intbl\qc\fs16 0.56 \cell +\pard\intbl\qc\fs16 0.83 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14APR2013 (113) \cell +\pard\intbl\qc\fs16 Cycle 16 \cell +\pard\intbl\qc\fs16 0.77 \cell +\pard\intbl\qc\fs16 0.75 \cell +\pard\intbl\qc\fs16 1.37 \cell +\pard\intbl\qc\fs16 0.41* \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12MAY2013 (141) \cell +\pard\intbl\qc\fs16 Cycle 20 \cell +\pard\intbl\qc\fs16 0.51 \cell +\pard\intbl\qc\fs16 0.61 \cell +\pard\intbl\qc\fs16 2.31 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 08JUN2013 (168) \cell +\pard\intbl\qc\fs16 Cycle 24 \cell +\pard\intbl\qc\fs16 0.49 \cell +\pard\intbl\qc\fs16 0.58 \cell +\pard\intbl\qc\fs16 4.34 \cell +\pard\intbl\qc\fs16 0.33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2639 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4920 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8184 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9168 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10018 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10868 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11717 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 24JUN2013 (184) \cell +\pard\intbl\qc\fs16 End Of Treatment \cell +\pard\intbl\qc\fs16 0.49 \cell +\pard\intbl\qc\fs16 0.64* \cell +\pard\intbl\qc\fs16 5.43* \cell +\pard\intbl\qc\fs16 0.24 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx940 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2639 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4920 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8184 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9168 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10018 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10868 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11717 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2639 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4920 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8184 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9168 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10018 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10868 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11717 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} +\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} +} \ No newline at end of file diff --git a/tests/testthat/_snaps/lsfvit01/lsfvit01.rtf b/tests/testthat/_snaps/lsfvit01/lsfvit01.rtf old mode 100755 new mode 100644 index e6572e1f..4dc85cee --- a/tests/testthat/_snaps/lsfvit01/lsfvit01.rtf +++ b/tests/testthat/_snaps/lsfvit01/lsfvit01.rtf @@ -3,15 +3,17 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3209 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6507 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7309 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10651 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11186 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11855 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx943 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1526 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2334 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3366 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5296 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6104 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6867 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7406 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8348 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9021 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11893 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSFVIT01:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -22,20 +24,24 @@ \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3209 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6507 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7309 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10651 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11186 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11855 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx943 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1526 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2334 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3366 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5296 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6104 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6867 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7406 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8348 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9021 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11893 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell @@ -44,2422 +50,2826 @@ \pard\intbl\qc\fs16 \keepn\trhdr Visit \cell \pard\intbl\qc\fs16 \keepn\trhdr Time Point \cell \pard\intbl\qc\fs16 \keepn\trhdr Result \cell +\pard\intbl\qc\fs16 \keepn\trhdr Clinically Significant? \cell \pard\intbl\qc\fs16 \keepn\trhdr Change From Baseline \cell \pard\intbl\qc\fs16 \keepn\trhdr Criteria \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 71 / M / Asian \cell -\pard\intbl\qc\fs16 Diastolic Blood Pressure Orthostatic (mmHg) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Screening \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 1 N \cell +\pard\intbl\qc\fs16 \keepn\trhdr Treatment-emergent? \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / Multiple \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 18 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell \pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -10 N \cell -\pard\intbl\qc\fs16 -11 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 22 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2014 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 10 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -10 N \cell -\pard\intbl\qc\fs16 -11 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -6 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 16 N \cell -\pard\intbl\qc\fs16 15 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14OCT2014 / 06:00 (211) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 22 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2014 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 16 N \cell -\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 27OCT2014 / 06:00 (224) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -6 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 20 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 18 N \cell -\pard\intbl\qc\fs16 17 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 18 N \cell -\pard\intbl\qc\fs16 17 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 21 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 19 H \cell -\pard\intbl\qc\fs16 18 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01APR2013 / 06:00 (207) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 21 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 L \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2014 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 19 H \cell -\pard\intbl\qc\fs16 18 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 06 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0 N \cell -\pard\intbl\qc\fs16 -1 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 16 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2014 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0 N \cell -\pard\intbl\qc\fs16 -1 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 21 N \cell -\pard\intbl\qc\fs16 20 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 20 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 6 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2014 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 17 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 21 N \cell -\pard\intbl\qc\fs16 20 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 11 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 08 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -14 N \cell -\pard\intbl\qc\fs16 -15 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 27JUN2013 / 06:00 (210) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 16 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2014 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 19 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -14 N \cell -\pard\intbl\qc\fs16 -15 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 10JUL2013 / 06:00 (223) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2015 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 22 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -14 N \cell -\pard\intbl\qc\fs16 -15 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 25JUL2013 / 06:00 (238) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 20 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 25 N \cell -\pard\intbl\qc\fs16 24 \cell +\pard\intbl\qc\fs16 07AUG2013 / 06:00 (251) \cell +\pard\intbl\qc\fs16 Cycle 15 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 11 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 79 / Female / Not reported \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 05DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 18 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2015 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 21 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 25 N \cell -\pard\intbl\qc\fs16 24 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 12DEC2013 / 06:00 (8) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2016 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 25 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 25 N \cell -\pard\intbl\qc\fs16 24 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26JUN2014 / 06:00 (204) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 15FEB2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 L \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 05:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 9 N \cell -\pard\intbl\qc\fs16 8 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2015 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 23 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 9 N \cell -\pard\intbl\qc\fs16 8 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 02MAR2013 / 06:00 (16) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2016 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 29 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 9 N \cell -\pard\intbl\qc\fs16 8 \cell +\pard\intbl\qc\fs16 16MAR2013 / 06:00 (30) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -11 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Pulse Rate Orthostatic (beats/min) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Screening \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 19 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Orthostatic Pulse Rate >15 \cell +\pard\intbl\qc\fs16 25MAR2013 / 06:00 (39) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 18 N \cell -\pard\intbl\qc\fs16 -1 \cell -\pard\intbl\qc\fs16 Orthostatic Pulse Rate >15 \cell +\pard\intbl\qc\fs16 14SEP2013 / 06:00 (212) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2014 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 10 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 18 N \cell -\pard\intbl\qc\fs16 -1 \cell -\pard\intbl\qc\fs16 Orthostatic Pulse Rate >15 \cell +\pard\intbl\qc\fs16 28SEP2013 / 06:00 (226) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -11 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 22 N \cell -\pard\intbl\qc\fs16 3 \cell -\pard\intbl\qc\fs16 Orthostatic Pulse Rate >15 \cell +\pard\intbl\qc\fs16 07OCT2013 / 06:00 (235) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2014 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 22JUL2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell \pard\intbl\qc\fs16 22 N \cell -\pard\intbl\qc\fs16 3 \cell -\pard\intbl\qc\fs16 Orthostatic Pulse Rate >15 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -18 L \cell -\pard\intbl\qc\fs16 -37 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 07AUG2012 / 06:00 (17) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -18 L \cell -\pard\intbl\qc\fs16 -37 \cell +\pard\intbl\qc\fs16 21AUG2012 / 06:00 (31) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 16 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -6 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 17 N \cell -\pard\intbl\qc\fs16 -2 \cell -\pard\intbl\qc\fs16 Orthostatic Pulse Rate >15 \cell +\pard\intbl\qc\fs16 04SEP2012 / 06:00 (45) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -10 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2014 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 17 N \cell -\pard\intbl\qc\fs16 -2 \cell -\pard\intbl\qc\fs16 Orthostatic Pulse Rate >15 \cell +\pard\intbl\qc\fs16 23SEP2012 / 06:00 (64) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 16 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -6 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell +\pard\intbl\qc\fs16 14OCT2012 / 06:00 (85) \cell \pard\intbl\qc\fs16 Cycle 06 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -18 N \cell -\pard\intbl\qc\fs16 -37 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 15 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -7 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2014 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -18 N \cell -\pard\intbl\qc\fs16 -37 \cell +\pard\intbl\qc\fs16 15NOV2012 / 06:00 (117) \cell +\pard\intbl\qc\fs16 Cycle 07 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 19 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -3 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 9 N \cell -\pard\intbl\qc\fs16 -10 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (145) \cell +\pard\intbl\qc\fs16 Cycle 08 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 24 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2014 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 17 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 9 N \cell -\pard\intbl\qc\fs16 -10 \cell +\pard\intbl\qc\fs16 11JAN2013 / 06:00 (174) \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -8 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 08 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 8 N \cell -\pard\intbl\qc\fs16 -11 \cell +\pard\intbl\qc\fs16 20JAN2013 / 06:00 (183) \cell +\pard\intbl\qc\fs16 Cycle 10 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -8 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2014 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 19 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 8 N \cell -\pard\intbl\qc\fs16 -11 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 19FEB2013 / 06:00 (213) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2015 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 22 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 8 N \cell -\pard\intbl\qc\fs16 -11 \cell +\pard\intbl\qc\fs16 05MAR2013 / 06:00 (227) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 16 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -6 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -1 N \cell -\pard\intbl\qc\fs16 -20 \cell +\pard\intbl\qc\fs16 19MAR2013 / 06:00 (241) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -10 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2015 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 21 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -1 N \cell -\pard\intbl\qc\fs16 -20 \cell +\pard\intbl\qc\fs16 07APR2013 / 06:00 (260) \cell +\pard\intbl\qc\fs16 Cycle 15 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 16 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -6 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2016 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 25 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -1 N \cell -\pard\intbl\qc\fs16 -20 \cell +\pard\intbl\qc\fs16 28APR2013 / 06:00 (281) \cell +\pard\intbl\qc\fs16 Cycle 17 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 15 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -7 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 05:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0 L \cell -\pard\intbl\qc\fs16 -19 \cell +\pard\intbl\qc\fs16 30MAY2013 / 06:00 (313) \cell +\pard\intbl\qc\fs16 Cycle 19 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 19 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -3 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2015 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 23 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0 L \cell -\pard\intbl\qc\fs16 -19 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 27JUN2013 / 06:00 (341) \cell +\pard\intbl\qc\fs16 Cycle 21 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 24 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2016 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 29 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0 L \cell -\pard\intbl\qc\fs16 -19 \cell +\pard\intbl\qc\fs16 26JUL2013 / 06:00 (370) \cell +\pard\intbl\qc\fs16 Cycle 23 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -8 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Systolic Blood Pressure Orthostatic (mmHg) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Screening \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -23 H \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Orthostatic SBP <-20 \cell +\pard\intbl\qc\fs16 04AUG2013 / 06:00 (379) \cell +\pard\intbl\qc\fs16 Cycle 25 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -8 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -19 H \cell -\pard\intbl\qc\fs16 4 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 09JAN2014 / 06:00 (537) \cell +\pard\intbl\qc\fs16 Cycle 29 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 24 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2014 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 10 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -19 H \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 07FEB2014 / 06:00 (566) \cell +\pard\intbl\qc\fs16 End Of Treatment \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -8 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 15NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 21 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -18 H \cell -\pard\intbl\qc\fs16 5 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2014 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -18 H \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 28NOV2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -8 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -13 H \cell -\pard\intbl\qc\fs16 10 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 11DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -13 H \cell -\pard\intbl\qc\fs16 10 \cell +\pard\intbl\qc\fs16 25DEC2012 / 06:00 (41) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 10 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -11 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell +\pard\intbl\qc\fs16 08JAN2013 / 06:00 (55) \cell \pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2 H \cell -\pard\intbl\qc\fs16 25 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2014 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 2 H \cell -\pard\intbl\qc\fs16 25 \cell +\pard\intbl\qc\fs16 12JUN2013 / 06:00 (210) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -8 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 06 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 26 H \cell -\pard\intbl\qc\fs16 49 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 25JUN2013 / 06:00 (223) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2014 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 26 H \cell -\pard\intbl\qc\fs16 49 \cell +\pard\intbl\qc\fs16 09JUL2013 / 06:00 (237) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 10 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -11 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -4 N \cell -\pard\intbl\qc\fs16 19 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23JUL2013 / 06:00 (251) \cell +\pard\intbl\qc\fs16 Cycle 15 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 68 / Male / Unknown \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 22MAY2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2014 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 17 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -4 N \cell -\pard\intbl\qc\fs16 19 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 08 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -6 N \cell -\pard\intbl\qc\fs16 17 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 05JUN2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 24 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 11 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2014 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 19 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -6 N \cell -\pard\intbl\qc\fs16 17 \cell +\pard\intbl\qc\fs16 19JUN2014 / 06:00 (29) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 16 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 3 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2015 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 22 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -6 N \cell -\pard\intbl\qc\fs16 17 \cell +\pard\intbl\qc\fs16 03JUL2014 / 06:00 (43) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 7 H \cell -\pard\intbl\qc\fs16 30 \cell +\pard\intbl\qc\fs16 22JUL2014 / 06:00 (62) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 10 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -3 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2015 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 21 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 7 H \cell -\pard\intbl\qc\fs16 30 \cell +\pard\intbl\qc\fs16 15AUG2014 / 06:00 (86) \cell +\pard\intbl\qc\fs16 Cycle 06 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 17 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 4 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2016 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 25 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 7 H \cell -\pard\intbl\qc\fs16 30 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 11SEP2014 / 06:00 (113) \cell +\pard\intbl\qc\fs16 Cycle 07 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 10 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 05:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -10 N \cell -\pard\intbl\qc\fs16 13 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 09OCT2014 / 06:00 (141) \cell +\pard\intbl\qc\fs16 Cycle 08 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 10 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2015 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 23 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -10 N \cell -\pard\intbl\qc\fs16 13 \cell +\pard\intbl\qc\fs16 06NOV2014 / 06:00 (169) \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2016 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 29 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -10 N \cell -\pard\intbl\qc\fs16 13 \cell +\pard\intbl\qc\fs16 20NOV2014 / 06:00 (183) \cell +\pard\intbl\qc\fs16 Cycle 10 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 18 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 5 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 77 / F / White \cell -\pard\intbl\qc\fs16 Diastolic Blood Pressure Orthostatic (mmHg) \cell -\pard\intbl\qc\fs16 01JUL2014 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Screening \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -8 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 18DEC2014 / 06:00 (211) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 24 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 11 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 15JUL2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -1 H \cell -\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 01JAN2015 / 06:00 (225) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 16 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 3 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 15JUL2015 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Cycle 10 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -1 H \cell -\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 15JAN2015 / 06:00 (239) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29JUL2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -15 N \cell -\pard\intbl\qc\fs16 -7 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 03FEB2015 / 06:00 (258) \cell +\pard\intbl\qc\fs16 Cycle 15 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 10 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -3 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29JUL2015 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -15 N \cell -\pard\intbl\qc\fs16 -7 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -6 N \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 27FEB2015 / 06:00 (282) \cell +\pard\intbl\qc\fs16 Cycle 17 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 17 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 4 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11AUG2015 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -6 N \cell -\pard\intbl\qc\fs16 2 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26MAR2015 / 06:00 (309) \cell +\pard\intbl\qc\fs16 Cycle 19 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 10 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26AUG2014 / 04:00 (57) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 1 N \cell -\pard\intbl\qc\fs16 9 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23APR2015 / 06:00 (337) \cell +\pard\intbl\qc\fs16 Cycle 21 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 10 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26AUG2015 / 04:00 (57) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 1 N \cell -\pard\intbl\qc\fs16 9 \cell +\pard\intbl\qc\fs16 21MAY2015 / 06:00 (365) \cell +\pard\intbl\qc\fs16 Cycle 23 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25SEP2014 / 04:00 (87) \cell -\pard\intbl\qc\fs16 Cycle 06 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -17 N \cell -\pard\intbl\qc\fs16 -9 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 04JUN2015 / 06:00 (379) \cell +\pard\intbl\qc\fs16 Cycle 25 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 18 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25SEP2015 / 04:00 (87) \cell -\pard\intbl\qc\fs16 Cycle 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -17 N \cell -\pard\intbl\qc\fs16 -9 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 05NOV2015 / 06:00 (533) \cell +\pard\intbl\qc\fs16 Cycle 29 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 23 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 10 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 21OCT2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 11 N \cell -\pard\intbl\qc\fs16 19 \cell +\pard\intbl\qc\fs16 03DEC2015 / 06:00 (561) \cell +\pard\intbl\qc\fs16 End Of Treatment \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 79 / Male / Asian \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 02OCT2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 21OCT2015 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Cycle 17 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 11 N \cell -\pard\intbl\qc\fs16 19 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 18NOV2014 / 05:00 (141) \cell -\pard\intbl\qc\fs16 Cycle 08 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -16 N \cell +\pard\intbl\qc\fs16 16OCT2012 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 17 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 -8 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 18NOV2015 / 05:00 (141) \cell -\pard\intbl\qc\fs16 Cycle 19 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -16 N \cell -\pard\intbl\qc\fs16 -8 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 30OCT2012 / 06:00 (29) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 15 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -10 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17NOV2016 / 05:00 (141) \cell -\pard\intbl\qc\fs16 Cycle 22 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -16 N \cell -\pard\intbl\qc\fs16 -8 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 13NOV2012 / 06:00 (43) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 20 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -5 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17DEC2014 / 05:00 (170) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 10 H \cell -\pard\intbl\qc\fs16 18 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 25NOV2012 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 17DEC2015 / 05:00 (170) \cell -\pard\intbl\qc\fs16 Cycle 21 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 10 H \cell -\pard\intbl\qc\fs16 18 \cell +\pard\intbl\qc\fs16 25DEC2012 / 06:00 (85) \cell +\pard\intbl\qc\fs16 Cycle 06 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -12 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 16DEC2016 / 05:00 (170) \cell -\pard\intbl\qc\fs16 Cycle 25 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 10 H \cell -\pard\intbl\qc\fs16 18 \cell +\pard\intbl\qc\fs16 22JAN2013 / 06:00 (113) \cell +\pard\intbl\qc\fs16 Cycle 07 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 17 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -8 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 30DEC2014 / 05:00 (183) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -8 N \cell -\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 19FEB2013 / 06:00 (141) \cell +\pard\intbl\qc\fs16 Cycle 08 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -13 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 30DEC2015 / 05:00 (183) \cell -\pard\intbl\qc\fs16 Cycle 23 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -8 N \cell -\pard\intbl\qc\fs16 0 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 19MAR2013 / 06:00 (169) \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 22 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -3 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 Y \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29DEC2016 / 05:00 (183) \cell -\pard\intbl\qc\fs16 Cycle 29 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -8 N \cell -\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 02APR2013 / 06:00 (183) \cell +\pard\intbl\qc\fs16 Cycle 10 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -12 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Pulse Rate Orthostatic (beats/min) \cell -\pard\intbl\qc\fs16 01JUL2014 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Screening \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 14 N \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 30APR2013 / 06:00 (211) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 17 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -8 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 15JUL2014 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 13 N \cell -\pard\intbl\qc\fs16 -1 \cell +\pard\intbl\qc\fs16 14MAY2013 / 06:00 (225) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 15 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -10 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 15JUL2015 / 04:00 (15) \cell -\pard\intbl\qc\fs16 Cycle 10 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 13 N \cell -\pard\intbl\qc\fs16 -1 \cell +\pard\intbl\qc\fs16 28MAY2013 / 06:00 (239) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 20 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -5 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29JUL2014 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -10 N \cell -\pard\intbl\qc\fs16 -24 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 09JUN2013 / 06:00 (251) \cell +\pard\intbl\qc\fs16 Cycle 15 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29JUL2015 / 04:00 (29) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -10 N \cell -\pard\intbl\qc\fs16 -24 \cell +\pard\intbl\qc\fs16 09JUL2013 / 06:00 (281) \cell +\pard\intbl\qc\fs16 Cycle 17 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -12 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 9 N \cell -\pard\intbl\qc\fs16 -5 \cell +\pard\intbl\qc\fs16 06AUG2013 / 06:00 (309) \cell +\pard\intbl\qc\fs16 Cycle 19 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 17 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -8 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 11AUG2015 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 9 N \cell -\pard\intbl\qc\fs16 -5 \cell +\pard\intbl\qc\fs16 03SEP2013 / 06:00 (337) \cell +\pard\intbl\qc\fs16 Cycle 21 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -13 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26AUG2014 / 04:00 (57) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 16 N \cell -\pard\intbl\qc\fs16 2 \cell -\pard\intbl\qc\fs16 Orthostatic Pulse Rate >15 \cell +\pard\intbl\qc\fs16 01OCT2013 / 06:00 (365) \cell +\pard\intbl\qc\fs16 Cycle 23 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 22 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -3 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26AUG2015 / 04:00 (57) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 16 N \cell -\pard\intbl\qc\fs16 2 \cell -\pard\intbl\qc\fs16 Orthostatic Pulse Rate >15 \cell +\pard\intbl\qc\fs16 15OCT2013 / 06:00 (379) \cell +\pard\intbl\qc\fs16 Cycle 25 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -12 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25SEP2014 / 04:00 (87) \cell -\pard\intbl\qc\fs16 Cycle 06 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -25 N \cell -\pard\intbl\qc\fs16 -39 \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (533) \cell +\pard\intbl\qc\fs16 Cycle 29 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -13 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 25SEP2015 / 04:00 (87) \cell -\pard\intbl\qc\fs16 Cycle 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -25 N \cell -\pard\intbl\qc\fs16 -39 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15APR2014 / 06:00 (561) \cell +\pard\intbl\qc\fs16 End Of Treatment \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 22 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -3 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3209 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6507 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10651 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11855 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx943 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1526 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2334 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3366 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5296 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6104 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6867 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7406 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8348 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9021 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11893 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 51 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 05JAN2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 13 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 21OCT2014 / 04:00 (113) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 21 N \cell -\pard\intbl\qc\fs16 7 \cell -\pard\intbl\qc\fs16 Orthostatic Pulse Rate >15 \cell +\pard\intbl\qc\fs16 N \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3209 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6507 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7309 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10651 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11186 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11855 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx943 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1526 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2334 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3366 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5296 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6104 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6867 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7406 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8348 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9021 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11893 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2470,20 +2880,24 @@ \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3209 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6507 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10651 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx943 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1526 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2334 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3366 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5296 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6104 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6867 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7406 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8348 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9021 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11893 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell @@ -2494,6 +2908,8 @@ \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell \row } \par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} diff --git a/tests/testthat/_snaps/lsfvit02/lsfvit02.rtf b/tests/testthat/_snaps/lsfvit02/lsfvit02.rtf old mode 100755 new mode 100644 index 97ef8304..6ce1ab24 --- a/tests/testthat/_snaps/lsfvit02/lsfvit02.rtf +++ b/tests/testthat/_snaps/lsfvit02/lsfvit02.rtf @@ -6,12 +6,14 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3699 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6997 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7799 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10027 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11186 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11855 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3387 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6730 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7398 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8691 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9671 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11275 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11899 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSFVIT02:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -22,6 +24,8 @@ \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } @@ -30,12 +34,14 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3699 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6997 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7799 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10027 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11186 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11855 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3387 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6730 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7398 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8691 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9671 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11275 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11899 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell @@ -44,8 +50,10 @@ \pard\intbl\qc\fs16 \keepn\trhdr Visit \cell \pard\intbl\qc\fs16 \keepn\trhdr Time Point \cell \pard\intbl\qc\fs16 \keepn\trhdr Result \cell +\pard\intbl\qc\fs16 \keepn\trhdr Clinically Significant? \cell \pard\intbl\qc\fs16 \keepn\trhdr Change From Baseline \cell \pard\intbl\qc\fs16 \keepn\trhdr Criteria \cell +\pard\intbl\qc\fs16 \keepn\trhdr Treatment-emergent? \cell \row } @@ -54,22 +62,26 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 71 / M / Asian \cell -\pard\intbl\qc\fs16 DBP (STD-SUP) <-10 \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Screening \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / Multiple \cell +\pard\intbl\qc\fs16 Systolic Blood Pressure (mmHg) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 124.3333 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -78,22 +90,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell \pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 128.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 4.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -102,22 +118,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2014 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 10 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 125.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 1.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -126,22 +146,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14OCT2014 / 06:00 (211) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 128.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 4.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -150,22 +174,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2014 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 27OCT2014 / 06:00 (224) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 125.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 1.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -174,22 +202,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell +\pard\intbl\qc\fs16 Diastolic Blood Pressure (mmHg) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 73.3333 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -198,22 +230,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 77.3333 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 4.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -222,22 +258,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 70.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -3.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -246,22 +286,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2014 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14OCT2014 / 06:00 (211) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 77.3333 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 4.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -270,22 +314,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 06 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 27OCT2014 / 06:00 (224) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 70.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -3.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -294,22 +342,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2014 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell +\pard\intbl\qc\fs16 Pulse Rate (beats/min) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 60.3333 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -318,22 +370,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 61.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -342,22 +398,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2014 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 17 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 56.3333 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -4.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -366,22 +426,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 08 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 Y N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14OCT2014 / 06:00 (211) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 61.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -390,22 +454,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2014 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 19 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 Y N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 27OCT2014 / 06:00 (224) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 56.3333 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -4.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -414,22 +482,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2015 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 22 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 Y N \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 18 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -438,22 +510,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 22 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -462,22 +538,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2015 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 21 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -6 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -486,22 +566,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2016 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 25 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14OCT2014 / 06:00 (211) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 22 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -510,22 +594,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 05:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 27OCT2014 / 06:00 (224) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 12 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -6 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -534,22 +622,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2015 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 23 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell +\pard\intbl\qc\fs16 Weight (kg) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 88.45 \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -558,22 +650,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2016 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 29 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 89.36 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.91 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -582,22 +678,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Diastolic Blood Pressure (mmHg) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Screening \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 78.6667 N \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 88.45 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.00 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -606,22 +706,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 79.3333 N \cell -\pard\intbl\qc\fs16 0.6667 \cell +\pard\intbl\qc\fs16 14OCT2014 / 06:00 (211) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 89.36 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.91 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -630,22 +734,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2014 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 10 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 79.3333 N \cell -\pard\intbl\qc\fs16 0.6667 \cell +\pard\intbl\qc\fs16 27OCT2014 / 06:00 (224) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 88.45 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.00 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -654,22 +762,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Temperature (C) \cell +\pard\intbl\qc\fs16 18MAR2014 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 37.11 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 69.6667 N \cell -\pard\intbl\qc\fs16 -9.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -678,22 +790,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2014 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 69.6667 N \cell -\pard\intbl\qc\fs16 -9.0000 \cell +\pard\intbl\qc\fs16 01APR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.72 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.39 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -702,22 +818,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 74.0000 N \cell -\pard\intbl\qc\fs16 -4.6667 \cell +\pard\intbl\qc\fs16 14APR2014 / 06:00 (28) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.72 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.39 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -726,22 +846,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 74.0000 N \cell -\pard\intbl\qc\fs16 -4.6667 \cell +\pard\intbl\qc\fs16 14OCT2014 / 06:00 (211) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.72 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.39 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -750,22 +874,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 80.3333 H \cell -\pard\intbl\qc\fs16 1.6667 \cell +\pard\intbl\qc\fs16 27OCT2014 / 06:00 (224) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.72 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.39 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -774,22 +902,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Systolic Blood Pressure (mmHg) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 133.3333 H \cell +\pard\intbl\qc\fs16 Y \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2014 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 80.3333 H \cell -\pard\intbl\qc\fs16 1.6667 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -798,22 +930,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 06 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 79.0000 N \cell -\pard\intbl\qc\fs16 0.3333 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 115.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -17.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -822,22 +958,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2014 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 79.0000 N \cell -\pard\intbl\qc\fs16 0.3333 \cell +\pard\intbl\qc\fs16 01APR2013 / 06:00 (207) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 115.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -17.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -846,22 +986,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Diastolic Blood Pressure (mmHg) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 71.6667 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 76.3333 N \cell -\pard\intbl\qc\fs16 -2.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -870,22 +1014,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2014 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 17 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 76.3333 N \cell -\pard\intbl\qc\fs16 -2.3333 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 62.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -9.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -894,22 +1042,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 08 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 77.3333 N \cell -\pard\intbl\qc\fs16 -1.3333 \cell +\pard\intbl\qc\fs16 01APR2013 / 06:00 (207) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 62.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -9.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -918,22 +1070,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Pulse Rate (beats/min) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 82.6667 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2014 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 19 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 77.3333 N \cell -\pard\intbl\qc\fs16 -1.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -942,22 +1098,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2015 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 22 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 77.3333 N \cell -\pard\intbl\qc\fs16 -1.3333 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 86.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 3.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -966,22 +1126,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 74.0000 N \cell -\pard\intbl\qc\fs16 -4.6667 \cell +\pard\intbl\qc\fs16 01APR2013 / 06:00 (207) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 86.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 3.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -990,22 +1154,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 20 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2015 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 21 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 74.0000 N \cell -\pard\intbl\qc\fs16 -4.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1014,22 +1182,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2016 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 25 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 74.0000 N \cell -\pard\intbl\qc\fs16 -4.6667 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 21 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1038,22 +1210,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 05:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 75.3333 N \cell -\pard\intbl\qc\fs16 -3.3333 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01APR2013 / 06:00 (207) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 21 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1062,22 +1238,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Weight (kg) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 59.88 \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2015 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 23 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 75.3333 N \cell -\pard\intbl\qc\fs16 -3.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1086,22 +1266,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2016 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 29 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 75.3333 N \cell -\pard\intbl\qc\fs16 -3.3333 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 60.78 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.90 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1110,22 +1294,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Diastolic Blood Pressure Orthostatic (mmHg) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Screening \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 1 N \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01APR2013 / 06:00 (207) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 60.78 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.90 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1134,22 +1322,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Temperature (C) \cell +\pard\intbl\qc\fs16 07SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.72 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -10 N \cell -\pard\intbl\qc\fs16 -11 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1158,22 +1350,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2014 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 10 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -10 N \cell -\pard\intbl\qc\fs16 -11 \cell +\pard\intbl\qc\fs16 17SEP2012 / 06:00 (11) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 37.11 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.39 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1182,22 +1378,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 16 N \cell -\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 01APR2013 / 06:00 (207) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 37.11 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.39 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1206,22 +1406,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Systolic Blood Pressure (mmHg) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 115.3333 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2014 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 16 N \cell -\pard\intbl\qc\fs16 15 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1230,22 +1434,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 18 N \cell -\pard\intbl\qc\fs16 17 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 113.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -1.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1254,22 +1462,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 18 N \cell -\pard\intbl\qc\fs16 17 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 102.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -12.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1278,22 +1490,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 19 H \cell -\pard\intbl\qc\fs16 18 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 114.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -1.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1302,22 +1518,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2014 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 19 H \cell -\pard\intbl\qc\fs16 18 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 111.3333 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -4.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1326,22 +1546,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 06 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0 N \cell -\pard\intbl\qc\fs16 -1 \cell +\pard\intbl\qc\fs16 27JUN2013 / 06:00 (210) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 113.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -1.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1350,22 +1574,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2014 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 0 N \cell -\pard\intbl\qc\fs16 -1 \cell +\pard\intbl\qc\fs16 10JUL2013 / 06:00 (223) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 102.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -12.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1374,22 +1602,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 21 N \cell -\pard\intbl\qc\fs16 20 \cell +\pard\intbl\qc\fs16 25JUL2013 / 06:00 (238) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 114.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -1.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1398,22 +1630,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2014 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 17 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 21 N \cell -\pard\intbl\qc\fs16 20 \cell +\pard\intbl\qc\fs16 07AUG2013 / 06:00 (251) \cell +\pard\intbl\qc\fs16 Cycle 15 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 111.3333 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -4.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1422,22 +1658,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Diastolic Blood Pressure (mmHg) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 73.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 08 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -14 N \cell -\pard\intbl\qc\fs16 -15 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1446,22 +1686,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2014 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 19 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -14 N \cell -\pard\intbl\qc\fs16 -15 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 72.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -1.0000 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1470,22 +1714,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2015 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 22 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 -14 N \cell -\pard\intbl\qc\fs16 -15 \cell -\pard\intbl\qc\fs16 Orthostatic DBP <-10 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 59.0000 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -14.0000 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1494,22 +1742,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 25 N \cell -\pard\intbl\qc\fs16 24 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 72.3333 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1518,22 +1770,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2015 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 21 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 25 N \cell -\pard\intbl\qc\fs16 24 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 62.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -10.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1542,22 +1798,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2016 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 25 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 25 N \cell -\pard\intbl\qc\fs16 24 \cell +\pard\intbl\qc\fs16 27JUN2013 / 06:00 (210) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 72.0000 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -1.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1566,22 +1826,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 05:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 9 N \cell -\pard\intbl\qc\fs16 8 \cell +\pard\intbl\qc\fs16 10JUL2013 / 06:00 (223) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 59.0000 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -14.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1590,22 +1854,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2015 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 23 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 9 N \cell -\pard\intbl\qc\fs16 8 \cell +\pard\intbl\qc\fs16 25JUL2013 / 06:00 (238) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 72.3333 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.6667 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1614,22 +1882,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2016 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 29 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 9 N \cell -\pard\intbl\qc\fs16 8 \cell +\pard\intbl\qc\fs16 07AUG2013 / 06:00 (251) \cell +\pard\intbl\qc\fs16 Cycle 15 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 62.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -10.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1638,22 +1910,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Orthostatic Hypotension \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Screening \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 Y H \cell +\pard\intbl\qc\fs16 Pulse Rate (beats/min) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 57.3333 L \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1662,22 +1938,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell \pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 62.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 5.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1686,22 +1966,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2014 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 10 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 57.3333 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1710,22 +1994,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 58.6667 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 1.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1734,22 +2022,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2014 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 52.0000 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -5.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1758,22 +2050,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 27JUN2013 / 06:00 (210) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 62.6667 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 5.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1782,22 +2078,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2014 / 04:00 (42) \cell +\pard\intbl\qc\fs16 10JUL2013 / 06:00 (223) \cell \pard\intbl\qc\fs16 Cycle 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 57.3333 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1806,22 +2106,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 25JUL2013 / 06:00 (238) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 58.6667 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 1.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1830,22 +2134,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2014 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 07AUG2013 / 06:00 (251) \cell +\pard\intbl\qc\fs16 Cycle 15 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 52.0000 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -5.3333 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1854,22 +2162,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 06 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell +\pard\intbl\qc\fs16 Respiratory Rate (breaths/min) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 L \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1878,22 +2190,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2014 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 16 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1902,22 +2218,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1926,22 +2246,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2014 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 17 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 20 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 6 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -1950,22 +2274,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2013 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 08 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 Y N \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 11 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1974,22 +2302,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2014 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 19 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 Y N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 27JUN2013 / 06:00 (210) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 16 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 2 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -1998,22 +2330,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 04DEC2015 / 05:00 (139) \cell -\pard\intbl\qc\fs16 Cycle 22 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 Y N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 10JUL2013 / 06:00 (223) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 14 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2022,22 +2358,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2014 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 09 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 25JUL2013 / 06:00 (238) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 20 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 6 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2046,22 +2386,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2015 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 21 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 07AUG2013 / 06:00 (251) \cell +\pard\intbl\qc\fs16 Cycle 15 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 25 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 11 \cell +\pard\intbl\qc\fs16 >20 breaths per minute \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2070,22 +2414,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06JAN2016 / 05:00 (172) \cell -\pard\intbl\qc\fs16 Cycle 25 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N H \cell +\pard\intbl\qc\fs16 Weight (kg) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 78.93 \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2094,22 +2442,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2014 / 05:00 (180) \cell -\pard\intbl\qc\fs16 End Of Treatment \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 78.93 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.00 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -2118,22 +2470,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2015 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 23 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 78.47 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.46 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -2142,22 +2498,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14JAN2016 / 05:00 (180) \cell -\pard\intbl\qc\fs16 Cycle 29 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 N N \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 78.47 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.46 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -2166,22 +2526,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Pulse Rate (beats/min) \cell -\pard\intbl\qc\fs16 19JUL2013 / 04:00 (1) \cell -\pard\intbl\qc\fs16 Screening \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 63.3333 N \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 78.47 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.46 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2190,22 +2554,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2013 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 02 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 71.3333 N \cell -\pard\intbl\qc\fs16 8.0000 \cell +\pard\intbl\qc\fs16 27JUN2013 / 06:00 (210) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 78.93 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.00 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2214,22 +2582,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 01AUG2014 / 04:00 (14) \cell -\pard\intbl\qc\fs16 Cycle 10 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 71.3333 N \cell -\pard\intbl\qc\fs16 8.0000 \cell +\pard\intbl\qc\fs16 10JUL2013 / 06:00 (223) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 78.47 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.46 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2238,22 +2610,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2013 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 03 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 75.0000 N \cell -\pard\intbl\qc\fs16 11.6667 \cell +\pard\intbl\qc\fs16 25JUL2013 / 06:00 (238) \cell +\pard\intbl\qc\fs16 Cycle 13 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 78.47 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.46 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2262,22 +2638,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 14AUG2014 / 04:00 (27) \cell -\pard\intbl\qc\fs16 Cycle 11 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 75.0000 N \cell -\pard\intbl\qc\fs16 11.6667 \cell +\pard\intbl\qc\fs16 07AUG2013 / 06:00 (251) \cell +\pard\intbl\qc\fs16 Cycle 15 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 78.47 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.46 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2286,22 +2666,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Temperature (C) \cell +\pard\intbl\qc\fs16 30NOV2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 Baseline \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.67 N \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2013 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 04 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 59.3333 L \cell -\pard\intbl\qc\fs16 -4.0000 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2310,22 +2694,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 29AUG2014 / 04:00 (42) \cell -\pard\intbl\qc\fs16 Cycle 12 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 59.3333 L \cell -\pard\intbl\qc\fs16 -4.0000 \cell +\pard\intbl\qc\fs16 13DEC2012 / 06:00 (14) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.67 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.00 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -2334,22 +2722,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2013 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 05 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 74.6667 N \cell -\pard\intbl\qc\fs16 11.3333 \cell +\pard\intbl\qc\fs16 26DEC2012 / 06:00 (27) \cell +\pard\intbl\qc\fs16 Cycle 03 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.50 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.17 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -2358,22 +2750,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 10SEP2014 / 04:00 (54) \cell -\pard\intbl\qc\fs16 Cycle 13 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 74.6667 N \cell -\pard\intbl\qc\fs16 11.3333 \cell +\pard\intbl\qc\fs16 10JAN2013 / 06:00 (42) \cell +\pard\intbl\qc\fs16 Cycle 04 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.44 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.23 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y \cell \row } @@ -2382,22 +2778,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2013 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 06 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 65.0000 N \cell -\pard\intbl\qc\fs16 1.6667 \cell +\pard\intbl\qc\fs16 23JAN2013 / 06:00 (55) \cell +\pard\intbl\qc\fs16 Cycle 05 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.44 L \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.23 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2406,22 +2806,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 09OCT2014 / 04:00 (83) \cell -\pard\intbl\qc\fs16 Cycle 15 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 65.0000 N \cell -\pard\intbl\qc\fs16 1.6667 \cell +\pard\intbl\qc\fs16 27JUN2013 / 06:00 (210) \cell +\pard\intbl\qc\fs16 Cycle 11 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.67 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 0.00 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2430,22 +2834,26 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3699 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6997 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7799 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10027 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11186 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11855 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3387 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8691 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9671 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11899 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 06NOV2013 / 05:00 (111) \cell -\pard\intbl\qc\fs16 Cycle 07 \cell -\pard\intbl\qc\fs16 BEFORE TREATMENT \cell -\pard\intbl\qc\fs16 66.3333 N \cell -\pard\intbl\qc\fs16 3.0000 \cell +\pard\intbl\qc\fs16 10JUL2013 / 06:00 (223) \cell +\pard\intbl\qc\fs16 Cycle 12 \cell +\pard\intbl\qc\fs16 Before treatment \cell +\pard\intbl\qc\fs16 36.50 N \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 -0.17 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell \row } @@ -2454,12 +2862,14 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3699 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6997 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7799 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10027 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11186 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11855 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3387 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6730 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7398 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8691 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9671 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10607 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11275 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11899 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2470,6 +2880,8 @@ \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } @@ -2478,12 +2890,14 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3699 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6997 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7799 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11186 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11855 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3387 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8691 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9671 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10607 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11899 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell @@ -2494,6 +2908,8 @@ \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell \row } \par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} diff --git a/tests/testthat/_snaps/lsicm01/lsicm01.rtf b/tests/testthat/_snaps/lsicm01/lsicm01.rtf old mode 100755 new mode 100644 index 11a9d871..25e30653 --- a/tests/testthat/_snaps/lsicm01/lsicm01.rtf +++ b/tests/testthat/_snaps/lsicm01/lsicm01.rtf @@ -3,17 +3,17 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx940 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1521 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2818 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3802 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4517 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6753 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7737 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8721 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9437 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10242 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11315 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3254 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4145 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5259 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6953 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7933 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8913 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9760 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10562 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11409 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSICM01:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -31,21 +31,21 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx940 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1521 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2818 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3802 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4517 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6753 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7737 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8721 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9437 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10242 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11315 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3254 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4145 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5259 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6953 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7933 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8913 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9760 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10562 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11409 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell -\pard\intbl\qc\fs16 \keepn\trhdr Medication (Verbatim) / Base Preferred Term \cell -\pard\intbl\qc\fs16 \keepn\trhdr Prior / Concomitant \cell +\pard\intbl\qc\fs16 \keepn\trhdr Medication (Verbatim) / Standardized Medication Name \cell +\pard\intbl\qc\fs16 \keepn\trhdr Medication Timing \cell \pard\intbl\qc\fs16 \keepn\trhdr Interest Category \cell \pard\intbl\qc\fs16 \keepn\trhdr ATC Level 1 / ATC Level 2 \cell \pard\intbl\qc\fs16 \keepn\trhdr Start Date of Medication (Study Day\super a\nosupersub ) \cell @@ -53,33 +53,33 @@ \pard\intbl\qc\fs16 \keepn\trhdr Dose (Unit) \cell \pard\intbl\qc\fs16 \keepn\trhdr Frequency \cell \pard\intbl\qc\fs16 \keepn\trhdr Route \cell -\pard\intbl\qc\fs16 \keepn\trhdr Indication:Specify \cell +\pard\intbl\qc\fs16 \keepn\trhdr Indication: Specify \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 Calcium / Calcium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -87,27 +87,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Calcium / Calcium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -115,27 +115,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Calcium / Calcium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -143,27 +143,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Calcium / Calcium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -171,27 +171,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Calcium / Calcium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -199,27 +199,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Calcium / Calcium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -227,27 +227,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Cod-liver oil / Uncoded: cod-liver oil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 CAPSULE \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -255,27 +255,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Cod-liver oil / Uncoded: cod-liver oil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 CAPSULE \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -283,27 +283,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Cod-liver oil / Uncoded: cod-liver oil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 CAPSULE \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -311,27 +311,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Cod-liver oil / Uncoded: cod-liver oil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 CAPSULE \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -339,27 +339,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Cod-liver oil / Uncoded: cod-liver oil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 CAPSULE \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -367,27 +367,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Cod-liver oil / Uncoded: cod-liver oil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 CAPSULE \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -395,27 +395,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Centrum / Uncoded: centrum \cell +\pard\intbl\qc\fs16 Zinc / Uncoded: zinc \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 APR2013 \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row @@ -423,643 +423,643 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Hydrocortisone / Hydrocortisone \cell -\pard\intbl\qc\fs16 C \cell -\pard\intbl\qc\fs16 Steroid \cell -\pard\intbl\qc\fs16 Systemic hormonal preparations, excl. / Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs16 08AUG2013 (21) \cell +\pard\intbl\qc\fs16 Zinc / Uncoded: zinc \cell +\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 PRN \cell -\pard\intbl\qc\fs16 Topical \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Hydrocortisone / Hydrocortisone \cell -\pard\intbl\qc\fs16 C \cell -\pard\intbl\qc\fs16 Steroid \cell -\pard\intbl\qc\fs16 Systemic hormonal preparations, excl. / Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs16 08AUG2013 (21) \cell +\pard\intbl\qc\fs16 Zinc / Uncoded: zinc \cell +\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 PRN \cell -\pard\intbl\qc\fs16 Topical \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Hydrocortisone / Hydrocortisone \cell -\pard\intbl\qc\fs16 C \cell -\pard\intbl\qc\fs16 Steroid \cell -\pard\intbl\qc\fs16 Systemic hormonal preparations, excl. / Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs16 08AUG2013 (21) \cell +\pard\intbl\qc\fs16 Zinc / Uncoded: zinc \cell +\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 PRN \cell -\pard\intbl\qc\fs16 Topical \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Hydrocortisone / Hydrocortisone \cell -\pard\intbl\qc\fs16 C \cell -\pard\intbl\qc\fs16 Steroid \cell -\pard\intbl\qc\fs16 Systemic hormonal preparations, excl. / Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs16 08AUG2013 (21) \cell +\pard\intbl\qc\fs16 Zinc / Uncoded: zinc \cell +\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 PRN \cell -\pard\intbl\qc\fs16 Topical \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Hydrocortisone / Hydrocortisone \cell -\pard\intbl\qc\fs16 C \cell -\pard\intbl\qc\fs16 Steroid \cell -\pard\intbl\qc\fs16 Systemic hormonal preparations, excl. / Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs16 08AUG2013 (21) \cell +\pard\intbl\qc\fs16 Zinc / Uncoded: zinc \cell +\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 PRN \cell -\pard\intbl\qc\fs16 Topical \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Hydrocortisone / Hydrocortisone \cell -\pard\intbl\qc\fs16 C \cell -\pard\intbl\qc\fs16 Steroid \cell -\pard\intbl\qc\fs16 Systemic hormonal preparations, excl. / Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs16 08AUG2013 (21) \cell +\pard\intbl\qc\fs16 Nitroglycerin / Uncoded: nitroglycerin \cell +\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 FEB2014 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 0.4 mg \cell \pard\intbl\qc\fs16 PRN \cell -\pard\intbl\qc\fs16 Topical \cell +\pard\intbl\qc\fs16 Sublingual \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Hydrocortisone / Hydrocortisone \cell -\pard\intbl\qc\fs16 C \cell -\pard\intbl\qc\fs16 Steroid \cell -\pard\intbl\qc\fs16 Systemic hormonal preparations, excl. / Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs16 08AUG2013 (21) \cell +\pard\intbl\qc\fs16 Nitroglycerin / Uncoded: nitroglycerin \cell +\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 FEB2014 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 0.4 mg \cell \pard\intbl\qc\fs16 PRN \cell -\pard\intbl\qc\fs16 Topical \cell +\pard\intbl\qc\fs16 Sublingual \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Hydrocortisone / Hydrocortisone \cell -\pard\intbl\qc\fs16 C \cell -\pard\intbl\qc\fs16 Steroid \cell -\pard\intbl\qc\fs16 Systemic hormonal preparations, excl. / Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs16 08AUG2013 (21) \cell +\pard\intbl\qc\fs16 Nitroglycerin / Uncoded: nitroglycerin \cell +\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 FEB2014 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 0.4 mg \cell \pard\intbl\qc\fs16 PRN \cell -\pard\intbl\qc\fs16 Topical \cell +\pard\intbl\qc\fs16 Sublingual \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Hydrocortisone / Hydrocortisone \cell -\pard\intbl\qc\fs16 C \cell -\pard\intbl\qc\fs16 Steroid \cell -\pard\intbl\qc\fs16 Systemic hormonal preparations, excl. / Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs16 08AUG2013 (21) \cell +\pard\intbl\qc\fs16 Nitroglycerin / Uncoded: nitroglycerin \cell +\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 FEB2014 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 0.4 mg \cell \pard\intbl\qc\fs16 PRN \cell -\pard\intbl\qc\fs16 Topical \cell +\pard\intbl\qc\fs16 Sublingual \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Nitroglycerin / Uncoded: nitroglycerin \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 FEB2014 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.4 mg \cell +\pard\intbl\qc\fs16 PRN \cell +\pard\intbl\qc\fs16 Sublingual \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Nitroglycerin / Uncoded: nitroglycerin \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 FEB2014 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.4 mg \cell +\pard\intbl\qc\fs16 PRN \cell +\pard\intbl\qc\fs16 Sublingual \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 Synthroid / Uncoded: synthroid \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 1983 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.075 mg \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Synthroid / Uncoded: synthroid \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 1983 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.075 mg \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Synthroid / Uncoded: synthroid \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 1983 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.075 mg \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Synthroid / Uncoded: synthroid \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 1983 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.075 mg \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Synthroid / Uncoded: synthroid \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 1983 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.075 mg \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Synthroid / Uncoded: synthroid \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 1983 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.075 mg \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Premarin / Estrogens conjugated \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 Genito urinary system and sex hormones / Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.625 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Premarin / Estrogens conjugated \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 Genito urinary system and sex hormones / Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.625 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Premarin / Estrogens conjugated \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 Genito urinary system and sex hormones / Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.625 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Premarin / Estrogens conjugated \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 Genito urinary system and sex hormones / Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.625 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Estrogen nos / Uncoded: estrogen nos \cell +\pard\intbl\qc\fs16 Premarin / Estrogens conjugated \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 Genito urinary system and sex hormones / Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 3 mL \cell -\pard\intbl\qc\fs16 OTHER \cell -\pard\intbl\qc\fs16 Intramuscular \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 0.625 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Premarin / Estrogens conjugated \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 Genito urinary system and sex hormones / Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 0.625 mg \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -1067,27 +1067,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Provera / Uncoded: provera \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 2.5 mg \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -1095,27 +1095,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Provera / Uncoded: provera \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 2.5 mg \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -1123,27 +1123,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Provera / Uncoded: provera \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 2.5 mg \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -1151,27 +1151,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Provera / Uncoded: provera \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 2.5 mg \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -1179,27 +1179,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Provera / Uncoded: provera \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 2.5 mg \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -1207,27 +1207,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Provera / Uncoded: provera \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 2.5 mg \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -1235,26 +1235,26 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Lisinopril / Uncoded: lisinopril \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 2006 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell +\pard\intbl\qc\fs16 2.5 mg \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell @@ -1263,26 +1263,26 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Lisinopril / Uncoded: lisinopril \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 2006 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell +\pard\intbl\qc\fs16 2.5 mg \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell @@ -1291,26 +1291,26 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Lisinopril / Uncoded: lisinopril \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 2006 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell +\pard\intbl\qc\fs16 2.5 mg \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell @@ -1319,26 +1319,26 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Lisinopril / Uncoded: lisinopril \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 2006 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell +\pard\intbl\qc\fs16 2.5 mg \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell @@ -1347,26 +1347,26 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Lisinopril / Uncoded: lisinopril \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 2006 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell +\pard\intbl\qc\fs16 2.5 mg \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell @@ -1375,26 +1375,26 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Levothroid / Uncoded: levothroid \cell +\pard\intbl\qc\fs16 Lisinopril / Uncoded: lisinopril \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1977 \cell +\pard\intbl\qc\fs16 2006 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 0.15 mg \cell +\pard\intbl\qc\fs16 2.5 mg \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell @@ -1403,755 +1403,755 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Motrin / Uncoded: motrin \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 2009 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Motrin / Uncoded: motrin \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 2009 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Motrin / Uncoded: motrin \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 2009 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Motrin / Uncoded: motrin \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 2009 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Motrin / Uncoded: motrin \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 2009 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Motrin / Uncoded: motrin \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 2009 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Keflex / Uncoded: keflex \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 08JUL2012 (-61) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 500 mg \cell +\pard\intbl\qc\fs16 QID \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Keflex / Uncoded: keflex \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 08JUL2012 (-61) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 500 mg \cell +\pard\intbl\qc\fs16 QID \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Keflex / Uncoded: keflex \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 08JUL2012 (-61) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 500 mg \cell +\pard\intbl\qc\fs16 QID \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Keflex / Uncoded: keflex \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 08JUL2012 (-61) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 500 mg \cell +\pard\intbl\qc\fs16 QID \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Keflex / Uncoded: keflex \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 08JUL2012 (-61) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 500 mg \cell +\pard\intbl\qc\fs16 QID \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Keflex / Uncoded: keflex \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 08JUL2012 (-61) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 500 mg \cell +\pard\intbl\qc\fs16 QID \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin c / Uncoded: vitamin c \cell +\pard\intbl\qc\fs16 Hydrocortisone, topical / Uncoded: hydrocortisone, topical \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell -\pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell -\pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 02SEP2012 (-5) \cell +\pard\intbl\qc\fs16 04SEP2012 (-3) \cell +\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 PRN \cell +\pard\intbl\qc\fs16 Topical \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell \pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell \pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell \pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell \pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell \pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell \pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell \pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell \pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell \pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell \pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 2011 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Metamucil / Uncoded: metamucil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 AUG2012 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 Tbsp \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Metamucil / Uncoded: metamucil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 AUG2012 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 Tbsp \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Vitamin e / Uncoded: vitamin e \cell +\pard\intbl\qc\fs16 Metamucil / Uncoded: metamucil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 AUG2012 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 Tbsp \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell +\pard\intbl\qc\fs16 Metamucil / Uncoded: metamucil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 AUG2012 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 Tbsp \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -2159,27 +2159,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell +\pard\intbl\qc\fs16 Metamucil / Uncoded: metamucil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 AUG2012 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 Tbsp \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -2187,27 +2187,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell +\pard\intbl\qc\fs16 Metamucil / Uncoded: metamucil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 AUG2012 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 Tbsp \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -2215,27 +2215,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell +\pard\intbl\qc\fs16 Metamucil / Uncoded: metamucil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 AUG2012 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 Tbsp \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -2243,27 +2243,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell +\pard\intbl\qc\fs16 Metamucil / Uncoded: metamucil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 AUG2012 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 Tbsp \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -2271,27 +2271,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell +\pard\intbl\qc\fs16 Metamucil / Uncoded: metamucil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 AUG2012 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 Tbsp \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -2299,27 +2299,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell +\pard\intbl\qc\fs16 Metamucil / Uncoded: metamucil \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 AUG2012 \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 1 Tbsp \cell +\pard\intbl\qc\fs16 PRN \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell \row @@ -2327,110 +2327,110 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell -\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 Hydrocortisone, topical / Uncoded: hydrocortisone, topical \cell +\pard\intbl\qc\fs16 C \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 11JAN2013 (43) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell -\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 PRN \cell +\pard\intbl\qc\fs16 Topical \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell -\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 Hydrocortisone, topical / Uncoded: hydrocortisone, topical \cell +\pard\intbl\qc\fs16 C \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 11JAN2013 (43) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell -\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 PRN \cell +\pard\intbl\qc\fs16 Topical \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell -\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 Hydrocortisone, topical / Uncoded: hydrocortisone, topical \cell +\pard\intbl\qc\fs16 C \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 11JAN2013 (43) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell -\pard\intbl\qc\fs16 Oral \cell +\pard\intbl\qc\fs16 1 VIAL \cell +\pard\intbl\qc\fs16 PRN \cell +\pard\intbl\qc\fs16 Topical \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell -\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 Hytrin / Uncoded: hytrin \cell +\pard\intbl\qc\fs16 F \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell -\pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell +\pard\intbl\qc\fs16 19APR2013 (141) \cell +\pard\intbl\qc\fs16 14MAY2013 (166) \cell +\pard\intbl\qc\fs16 2 mg \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell \pard\intbl\qc\fs16 \cell @@ -2439,108 +2439,108 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell -\pard\intbl\qc\fs16 P \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 Aspirin / Acetylsalicylic acid \cell +\pard\intbl\qc\fs16 F \cell +\pard\intbl\qc\fs16 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs16 Nervous system / Nervous system \cell +\pard\intbl\qc\fs16 29APR2013 (151) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell +\pard\intbl\qc\fs16 80 mg \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Ex-lax / Uncoded: ex-lax \cell -\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 Feosol / Uncoded: feosol \cell +\pard\intbl\qc\fs16 F \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 Uncoded / Uncoded \cell -\pard\intbl\qc\fs16 2001 \cell +\pard\intbl\qc\fs16 29APR2013 (151) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell -\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 325 mg \cell +\pard\intbl\qc\fs16 BID \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell -\pard\intbl\qc\fs16 P \cell +\pard\intbl\qc\fs16 Pravachol / Uncoded: pravachol \cell +\pard\intbl\qc\fs16 F \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 08MAY2013 (160) \cell \pard\intbl\qc\fs16 Ongoing \cell -\pard\intbl\qc\fs16 1 TABLET \cell +\pard\intbl\qc\fs16 20 mg \cell \pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 Oral \cell -\pard\intbl\qc\fs16 PROPHYLAXIS OR NON-THERAPEUTIC USE \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 Calcium magnesium / Uncoded: calcium magnesium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2551,24 +2551,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Calcium magnesium / Uncoded: calcium magnesium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2579,24 +2579,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Calcium magnesium / Uncoded: calcium magnesium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2607,24 +2607,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Calcium magnesium / Uncoded: calcium magnesium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2635,24 +2635,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Calcium magnesium / Uncoded: calcium magnesium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2663,24 +2663,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Calcium magnesium / Uncoded: calcium magnesium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2691,24 +2691,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Potassium / Uncoded: potassium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2719,24 +2719,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Potassium / Uncoded: potassium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2747,24 +2747,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Potassium / Uncoded: potassium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2775,24 +2775,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Potassium / Uncoded: potassium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2803,24 +2803,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Potassium / Uncoded: potassium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2831,24 +2831,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx940 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1521 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2818 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3802 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6753 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7737 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8721 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9437 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10242 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11315 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3254 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4145 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5259 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6953 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7933 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8913 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9760 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10562 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11409 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Calcium / Calcium \cell +\pard\intbl\qc\fs16 Potassium / Uncoded: potassium \cell \pard\intbl\qc\fs16 P \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Alimentary tract and metabolism / Alimentary tract and metabolism \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Uncoded / Uncoded \cell +\pard\intbl\qc\fs16 1985 \cell \pard\intbl\qc\fs16 Ongoing \cell \pard\intbl\qc\fs16 1 TABLET \cell \pard\intbl\qc\fs16 QD \cell @@ -2859,17 +2859,17 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx940 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1521 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2818 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3802 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4517 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6753 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7737 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8721 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9437 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10242 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11315 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3254 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4145 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5259 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6953 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7933 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8913 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9760 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10562 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11409 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2887,17 +2887,17 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2818 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3802 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6753 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7737 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9437 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10242 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11315 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4145 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5259 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6953 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7933 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8913 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9760 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10562 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11409 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/lsidem01/lsidem01.rtf b/tests/testthat/_snaps/lsidem01/lsidem01.rtf old mode 100755 new mode 100644 index ad958868..b4af88a9 --- a/tests/testthat/_snaps/lsidem01/lsidem01.rtf +++ b/tests/testthat/_snaps/lsidem01/lsidem01.rtf @@ -3,16 +3,16 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2095 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5081 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6106 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9092 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10429 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11008 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11543 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12167 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx970 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3880 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4619 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5404 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6466 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9561 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10346 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10946 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11500 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12147 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIDEM01:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -29,16 +29,16 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2095 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5081 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6106 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9092 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10429 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11008 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11543 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12167 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx970 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3880 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4619 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5404 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6466 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9561 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10346 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10946 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11500 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12147 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Region \cell @@ -55,49 +55,23 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 11JUL2013 \cell -\pard\intbl\qc\fs16 71 / M / Asian \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 68.0 \cell -\pard\intbl\qc\fs16 103.0 \cell -\pard\intbl\qc\fs16 101.00 \cell -\pard\intbl\qc\fs16 72.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 24JUN2014 \cell -\pard\intbl\qc\fs16 77 / F / White \cell -\pard\intbl\qc\fs16 Unknown \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 10MAR2014 \cell +\pard\intbl\qc\fs16 74 / Male / Multiple \cell +\pard\intbl\qc\fs16 Not reported \cell \pard\intbl\qc\fs16 75.0 \cell \pard\intbl\qc\fs16 47.0 \cell \pard\intbl\qc\fs16 142.00 \cell @@ -107,308 +81,308 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1133 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 23OCT2012 \cell -\pard\intbl\qc\fs16 81 / F / Other \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 117.0 \cell -\pard\intbl\qc\fs16 76.0 \cell -\pard\intbl\qc\fs16 87.00 \cell -\pard\intbl\qc\fs16 90.00 \cell +\pard\intbl\qc\fs16 01-701-1097 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 23DEC2013 \cell +\pard\intbl\qc\fs16 68 / Male / Other \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 3.0 \cell +\pard\intbl\qc\fs16 54.0 \cell +\pard\intbl\qc\fs16 80.00 \cell +\pard\intbl\qc\fs16 92.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1146 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 07MAY2013 \cell -\pard\intbl\qc\fs16 75 / F / Unknown \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 119.0 \cell -\pard\intbl\qc\fs16 67.0 \cell -\pard\intbl\qc\fs16 134.00 \cell -\pard\intbl\qc\fs16 135.00 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 25AUG2012 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 105.0 \cell +\pard\intbl\qc\fs16 124.0 \cell +\pard\intbl\qc\fs16 129.00 \cell +\pard\intbl\qc\fs16 52.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1148 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 14AUG2013 \cell -\pard\intbl\qc\fs16 57 / M / Not reported \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 10.0 \cell -\pard\intbl\qc\fs16 126.0 \cell -\pard\intbl\qc\fs16 14.00 \cell -\pard\intbl\qc\fs16 64.00 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 23NOV2012 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 110.0 \cell +\pard\intbl\qc\fs16 16.0 \cell +\pard\intbl\qc\fs16 50.00 \cell +\pard\intbl\qc\fs16 15.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1180 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 28JAN2013 \cell -\pard\intbl\qc\fs16 56 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 03FEB2013 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell \pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 14.0 \cell -\pard\intbl\qc\fs16 8.0 \cell -\pard\intbl\qc\fs16 24.00 \cell -\pard\intbl\qc\fs16 66.00 \cell +\pard\intbl\qc\fs16 35.0 \cell +\pard\intbl\qc\fs16 23.0 \cell +\pard\intbl\qc\fs16 133.00 \cell +\pard\intbl\qc\fs16 22.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1181 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 26NOV2013 \cell -\pard\intbl\qc\fs16 79 / F / Not reported \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 107.0 \cell -\pard\intbl\qc\fs16 36.0 \cell -\pard\intbl\qc\fs16 137.00 \cell -\pard\intbl\qc\fs16 31.00 \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 08JUL2012 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 130.0 \cell +\pard\intbl\qc\fs16 13.0 \cell +\pard\intbl\qc\fs16 11.00 \cell +\pard\intbl\qc\fs16 81.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1239 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 28DEC2013 \cell -\pard\intbl\qc\fs16 56 / M / White \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 119.0 \cell -\pard\intbl\qc\fs16 110.0 \cell -\pard\intbl\qc\fs16 54.00 \cell -\pard\intbl\qc\fs16 114.00 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 30OCT2012 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 67.0 \cell +\pard\intbl\qc\fs16 115.0 \cell +\pard\intbl\qc\fs16 7.00 \cell +\pard\intbl\qc\fs16 150.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1275 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 25JAN2014 \cell -\pard\intbl\qc\fs16 61 / M / White \cell -\pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 100.0 \cell -\pard\intbl\qc\fs16 118.0 \cell -\pard\intbl\qc\fs16 108.00 \cell -\pard\intbl\qc\fs16 37.00 \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17MAR2013 \cell +\pard\intbl\qc\fs16 67 / Male / Other \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 66.0 \cell +\pard\intbl\qc\fs16 64.0 \cell +\pard\intbl\qc\fs16 76.00 \cell +\pard\intbl\qc\fs16 115.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1287 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 17JAN2014 \cell -\pard\intbl\qc\fs16 56 / F / Multiple \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 10MAY2014 \cell +\pard\intbl\qc\fs16 68 / Male / Unknown \cell \pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 23.0 \cell -\pard\intbl\qc\fs16 71.0 \cell -\pard\intbl\qc\fs16 47.00 \cell -\pard\intbl\qc\fs16 29.00 \cell +\pard\intbl\qc\fs16 92.0 \cell +\pard\intbl\qc\fs16 45.0 \cell +\pard\intbl\qc\fs16 30.00 \cell +\pard\intbl\qc\fs16 95.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1302 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 20AUG2013 \cell -\pard\intbl\qc\fs16 61 / M / Asian \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 66.0 \cell -\pard\intbl\qc\fs16 64.0 \cell -\pard\intbl\qc\fs16 76.00 \cell -\pard\intbl\qc\fs16 115.00 \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 16SEP2012 \cell +\pard\intbl\qc\fs16 79 / Male / Asian \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 132.0 \cell +\pard\intbl\qc\fs16 22.0 \cell +\pard\intbl\qc\fs16 107.00 \cell +\pard\intbl\qc\fs16 125.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1360 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 24JUL2013 \cell -\pard\intbl\qc\fs16 67 / M / Multiple \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 10.0 \cell -\pard\intbl\qc\fs16 38.0 \cell -\pard\intbl\qc\fs16 91.00 \cell -\pard\intbl\qc\fs16 96.00 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 22DEC2012 \cell +\pard\intbl\qc\fs16 51 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 87.0 \cell +\pard\intbl\qc\fs16 148.0 \cell +\pard\intbl\qc\fs16 32.00 \cell +\pard\intbl\qc\fs16 74.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1383 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 22JAN2013 \cell -\pard\intbl\qc\fs16 72 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 73.0 \cell -\pard\intbl\qc\fs16 46.0 \cell -\pard\intbl\qc\fs16 62.00 \cell -\pard\intbl\qc\fs16 16.00 \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 25FEB2013 \cell +\pard\intbl\qc\fs16 84 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 41.0 \cell +\pard\intbl\qc\fs16 136.0 \cell +\pard\intbl\qc\fs16 91.00 \cell +\pard\intbl\qc\fs16 120.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1444 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 31DEC2012 \cell -\pard\intbl\qc\fs16 63 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-701-1442 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17OCT2013 \cell +\pard\intbl\qc\fs16 57 / Female / Asian \cell \pard\intbl\qc\fs16 Unknown \cell \pard\intbl\qc\fs16 16.0 \cell \pard\intbl\qc\fs16 125.0 \cell @@ -419,231 +393,231 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1076 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 17OCT2013 \cell -\pard\intbl\qc\fs16 69 / M / White \cell +\pard\intbl\qc\fs16 01-702-1082 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 03JUL2013 \cell +\pard\intbl\qc\fs16 84 / Female / Asian \cell \pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 129.0 \cell -\pard\intbl\qc\fs16 32.0 \cell -\pard\intbl\qc\fs16 74.00 \cell -\pard\intbl\qc\fs16 135.00 \cell +\pard\intbl\qc\fs16 108.0 \cell +\pard\intbl\qc\fs16 150.0 \cell +\pard\intbl\qc\fs16 145.00 \cell +\pard\intbl\qc\fs16 48.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1258 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 10JUL2012 \cell -\pard\intbl\qc\fs16 78 / F / Black or African American \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 24.0 \cell -\pard\intbl\qc\fs16 143.0 \cell -\pard\intbl\qc\fs16 113.00 \cell -\pard\intbl\qc\fs16 48.00 \cell +\pard\intbl\qc\fs16 01-703-1086 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 22AUG2012 \cell +\pard\intbl\qc\fs16 71 / Male / Multiple \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 110.0 \cell +\pard\intbl\qc\fs16 59.0 \cell +\pard\intbl\qc\fs16 127.00 \cell +\pard\intbl\qc\fs16 97.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1295 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 24OCT2013 \cell -\pard\intbl\qc\fs16 88 / F / Other \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 111.0 \cell -\pard\intbl\qc\fs16 88.0 \cell -\pard\intbl\qc\fs16 139.00 \cell -\pard\intbl\qc\fs16 138.00 \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 02FEB2013 \cell +\pard\intbl\qc\fs16 81 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 109.0 \cell +\pard\intbl\qc\fs16 62.0 \cell +\pard\intbl\qc\fs16 40.00 \cell +\pard\intbl\qc\fs16 76.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1335 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 28FEB2014 \cell -\pard\intbl\qc\fs16 67 / F / Not reported \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 08OCT2013 \cell +\pard\intbl\qc\fs16 84 / Male / Other \cell \pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 20.0 \cell -\pard\intbl\qc\fs16 45.0 \cell -\pard\intbl\qc\fs16 141.00 \cell -\pard\intbl\qc\fs16 97.00 \cell +\pard\intbl\qc\fs16 8.0 \cell +\pard\intbl\qc\fs16 36.0 \cell +\pard\intbl\qc\fs16 121.00 \cell +\pard\intbl\qc\fs16 19.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1403 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 05DEC2012 \cell -\pard\intbl\qc\fs16 67 / M / Multiple \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 104.0 \cell -\pard\intbl\qc\fs16 118.0 \cell -\pard\intbl\qc\fs16 142.00 \cell -\pard\intbl\qc\fs16 13.00 \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 01JUN2013 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 22.0 \cell +\pard\intbl\qc\fs16 82.0 \cell +\pard\intbl\qc\fs16 5.00 \cell +\pard\intbl\qc\fs16 136.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1439 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 04MAR2014 \cell -\pard\intbl\qc\fs16 76 / F / White \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 3.0 \cell -\pard\intbl\qc\fs16 23.0 \cell -\pard\intbl\qc\fs16 60.00 \cell -\pard\intbl\qc\fs16 87.00 \cell +\pard\intbl\qc\fs16 01-703-1279 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 27APR2013 \cell +\pard\intbl\qc\fs16 72 / Female / Unknown \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 111.0 \cell +\pard\intbl\qc\fs16 88.0 \cell +\pard\intbl\qc\fs16 139.00 \cell +\pard\intbl\qc\fs16 138.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1008 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 06JAN2013 \cell -\pard\intbl\qc\fs16 76 / F / White \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 70.0 \cell -\pard\intbl\qc\fs16 4.0 \cell -\pard\intbl\qc\fs16 122.00 \cell -\pard\intbl\qc\fs16 36.00 \cell +\pard\intbl\qc\fs16 01-703-1379 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 12SEP2013 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 47.0 \cell +\pard\intbl\qc\fs16 7.0 \cell +\pard\intbl\qc\fs16 79.00 \cell +\pard\intbl\qc\fs16 61.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1017 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 20SEP2013 \cell -\pard\intbl\qc\fs16 77 / M / Asian \cell +\pard\intbl\qc\fs16 01-704-1009 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 20AUG2013 \cell +\pard\intbl\qc\fs16 83 / Male / Unknown \cell \pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 123.0 \cell -\pard\intbl\qc\fs16 98.0 \cell -\pard\intbl\qc\fs16 33.00 \cell -\pard\intbl\qc\fs16 137.00 \cell +\pard\intbl\qc\fs16 49.0 \cell +\pard\intbl\qc\fs16 100.0 \cell +\pard\intbl\qc\fs16 130.00 \cell +\pard\intbl\qc\fs16 92.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1065 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 17OCT2013 \cell -\pard\intbl\qc\fs16 75 / M / Multiple \cell -\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 18SEP2013 \cell +\pard\intbl\qc\fs16 81 / Female / Asian \cell +\pard\intbl\qc\fs16 Not reported \cell \pard\intbl\qc\fs16 74.0 \cell \pard\intbl\qc\fs16 34.0 \cell \pard\intbl\qc\fs16 58.00 \cell @@ -653,127 +627,153 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1074 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 19JAN2014 \cell -\pard\intbl\qc\fs16 80 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 59.0 \cell -\pard\intbl\qc\fs16 9.0 \cell -\pard\intbl\qc\fs16 29.00 \cell -\pard\intbl\qc\fs16 149.00 \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 09JAN2013 \cell +\pard\intbl\qc\fs16 77 / Male / Multiple \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 120.0 \cell +\pard\intbl\qc\fs16 2.0 \cell +\pard\intbl\qc\fs16 56.00 \cell +\pard\intbl\qc\fs16 126.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1093 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 22FEB2013 \cell -\pard\intbl\qc\fs16 79 / M / American Indian or Alaska Native \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 84.0 \cell -\pard\intbl\qc\fs16 11.0 \cell -\pard\intbl\qc\fs16 143.00 \cell -\pard\intbl\qc\fs16 10.00 \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 18NOV2013 \cell +\pard\intbl\qc\fs16 71 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 113.0 \cell +\pard\intbl\qc\fs16 25.0 \cell +\pard\intbl\qc\fs16 63.00 \cell +\pard\intbl\qc\fs16 139.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1241 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 14AUG2013 \cell -\pard\intbl\qc\fs16 86 / M / Not reported \cell -\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 01-704-1135 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 23OCT2013 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 97.0 \cell \pard\intbl\qc\fs16 7.0 \cell -\pard\intbl\qc\fs16 82.0 \cell -\pard\intbl\qc\fs16 57.00 \cell -\pard\intbl\qc\fs16 69.00 \cell +\pard\intbl\qc\fs16 110.00 \cell +\pard\intbl\qc\fs16 81.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1266 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 05OCT2013 \cell -\pard\intbl\qc\fs16 82 / M / Multiple \cell -\pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 122.0 \cell -\pard\intbl\qc\fs16 31.0 \cell -\pard\intbl\qc\fs16 61.00 \cell -\pard\intbl\qc\fs16 35.00 \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 11NOV2012 \cell +\pard\intbl\qc\fs16 81 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 12.0 \cell +\pard\intbl\qc\fs16 132.0 \cell +\pard\intbl\qc\fs16 116.00 \cell +\pard\intbl\qc\fs16 48.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1332 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 24NOV2013 \cell -\pard\intbl\qc\fs16 80 / M / Multiple \cell -\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 13JUN2013 \cell +\pard\intbl\qc\fs16 68 / Female / Not reported \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 86.0 \cell +\pard\intbl\qc\fs16 144.0 \cell +\pard\intbl\qc\fs16 103.00 \cell +\pard\intbl\qc\fs16 109.00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 16APR2014 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Unknown \cell \pard\intbl\qc\fs16 16.0 \cell \pard\intbl\qc\fs16 118.0 \cell \pard\intbl\qc\fs16 21.00 \cell @@ -783,75 +783,75 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1280 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 11JAN2014 \cell -\pard\intbl\qc\fs16 56 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 147.0 \cell -\pard\intbl\qc\fs16 6.0 \cell -\pard\intbl\qc\fs16 108.00 \cell -\pard\intbl\qc\fs16 80.00 \cell +\pard\intbl\qc\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17NOV2013 \cell +\pard\intbl\qc\fs16 56 / Female / Not reported \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 18.0 \cell +\pard\intbl\qc\fs16 11.0 \cell +\pard\intbl\qc\fs16 141.00 \cell +\pard\intbl\qc\fs16 113.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1281 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 26NOV2013 \cell -\pard\intbl\qc\fs16 73 / F / Not reported \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 11SEP2013 \cell +\pard\intbl\qc\fs16 87 / Male / Black or African American \cell \pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 90.0 \cell -\pard\intbl\qc\fs16 137.0 \cell -\pard\intbl\qc\fs16 38.00 \cell -\pard\intbl\qc\fs16 98.00 \cell +\pard\intbl\qc\fs16 17.0 \cell +\pard\intbl\qc\fs16 51.0 \cell +\pard\intbl\qc\fs16 120.00 \cell +\pard\intbl\qc\fs16 100.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1303 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 10DEC2013 \cell -\pard\intbl\qc\fs16 72 / M / Unknown \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 01-705-1292 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 11OCT2013 \cell +\pard\intbl\qc\fs16 60 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Unknown \cell \pard\intbl\qc\fs16 52.0 \cell \pard\intbl\qc\fs16 48.0 \cell \pard\intbl\qc\fs16 3.00 \cell @@ -861,283 +861,283 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1310 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 26OCT2013 \cell -\pard\intbl\qc\fs16 74 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 62.0 \cell -\pard\intbl\qc\fs16 68.0 \cell -\pard\intbl\qc\fs16 9.00 \cell -\pard\intbl\qc\fs16 50.00 \cell +\pard\intbl\qc\fs16 01-705-1393 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 02SEP2012 \cell +\pard\intbl\qc\fs16 84 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 17.0 \cell +\pard\intbl\qc\fs16 46.0 \cell +\pard\intbl\qc\fs16 20.00 \cell +\pard\intbl\qc\fs16 61.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1377 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 29DEC2013 \cell -\pard\intbl\qc\fs16 63 / F / Unknown \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 82.0 \cell -\pard\intbl\qc\fs16 75.0 \cell -\pard\intbl\qc\fs16 114.00 \cell -\pard\intbl\qc\fs16 16.00 \cell +\pard\intbl\qc\fs16 01-705-1431 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 16JUN2013 \cell +\pard\intbl\qc\fs16 68 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 43.0 \cell +\pard\intbl\qc\fs16 70.0 \cell +\pard\intbl\qc\fs16 124.00 \cell +\pard\intbl\qc\fs16 85.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1382 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 09MAY2013 \cell -\pard\intbl\qc\fs16 82 / M / Multiple \cell +\pard\intbl\qc\fs16 01-706-1384 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 25AUG2012 \cell +\pard\intbl\qc\fs16 74 / Female / Multiple \cell \pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 54.0 \cell -\pard\intbl\qc\fs16 137.0 \cell -\pard\intbl\qc\fs16 114.00 \cell -\pard\intbl\qc\fs16 114.00 \cell +\pard\intbl\qc\fs16 28.0 \cell +\pard\intbl\qc\fs16 109.0 \cell +\pard\intbl\qc\fs16 35.00 \cell +\pard\intbl\qc\fs16 103.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-706-1049 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 30APR2013 \cell -\pard\intbl\qc\fs16 60 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 91.0 \cell -\pard\intbl\qc\fs16 116.0 \cell -\pard\intbl\qc\fs16 129.00 \cell -\pard\intbl\qc\fs16 31.00 \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 12DEC2013 \cell +\pard\intbl\qc\fs16 72 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 119.0 \cell +\pard\intbl\qc\fs16 149.0 \cell +\pard\intbl\qc\fs16 9.00 \cell +\pard\intbl\qc\fs16 123.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1178 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 13DEC2013 \cell -\pard\intbl\qc\fs16 77 / F / Unknown \cell +\pard\intbl\qc\fs16 01-708-1019 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 10DEC2013 \cell +\pard\intbl\qc\fs16 68 / Male / Asian \cell \pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 123.0 \cell -\pard\intbl\qc\fs16 89.0 \cell -\pard\intbl\qc\fs16 4.00 \cell -\pard\intbl\qc\fs16 122.00 \cell +\pard\intbl\qc\fs16 63.0 \cell +\pard\intbl\qc\fs16 109.0 \cell +\pard\intbl\qc\fs16 129.00 \cell +\pard\intbl\qc\fs16 35.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1213 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 01FEB2013 \cell -\pard\intbl\qc\fs16 76 / F / Unknown \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 111.0 \cell -\pard\intbl\qc\fs16 34.0 \cell -\pard\intbl\qc\fs16 9.00 \cell -\pard\intbl\qc\fs16 31.00 \cell +\pard\intbl\qc\fs16 01-708-1032 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 02FEB2013 \cell +\pard\intbl\qc\fs16 62 / Male / Multiple \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 76.0 \cell +\pard\intbl\qc\fs16 17.0 \cell +\pard\intbl\qc\fs16 104.00 \cell +\pard\intbl\qc\fs16 68.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1216 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 14OCT2012 \cell -\pard\intbl\qc\fs16 78 / M / Asian \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 4.0 \cell -\pard\intbl\qc\fs16 53.0 \cell -\pard\intbl\qc\fs16 129.00 \cell +\pard\intbl\qc\fs16 01-708-1084 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 01MAY2013 \cell +\pard\intbl\qc\fs16 73 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 9.0 \cell +\pard\intbl\qc\fs16 14.0 \cell \pard\intbl\qc\fs16 86.00 \cell +\pard\intbl\qc\fs16 26.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1236 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 08SEP2013 \cell -\pard\intbl\qc\fs16 86 / F / White \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 22JAN2013 \cell +\pard\intbl\qc\fs16 82 / Male / Not reported \cell \pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 99.0 \cell -\pard\intbl\qc\fs16 72.0 \cell -\pard\intbl\qc\fs16 98.00 \cell -\pard\intbl\qc\fs16 84.00 \cell +\pard\intbl\qc\fs16 102.0 \cell +\pard\intbl\qc\fs16 141.0 \cell +\pard\intbl\qc\fs16 60.00 \cell +\pard\intbl\qc\fs16 78.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1336 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 21NOV2012 \cell -\pard\intbl\qc\fs16 73 / M / Other \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 30.0 \cell -\pard\intbl\qc\fs16 88.0 \cell -\pard\intbl\qc\fs16 135.00 \cell -\pard\intbl\qc\fs16 88.00 \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 15JAN2013 \cell +\pard\intbl\qc\fs16 61 / Male / Not reported \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 33.0 \cell +\pard\intbl\qc\fs16 19.0 \cell +\pard\intbl\qc\fs16 73.00 \cell +\pard\intbl\qc\fs16 47.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1347 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 11APR2013 \cell -\pard\intbl\qc\fs16 61 / F / White \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 45.0 \cell -\pard\intbl\qc\fs16 75.0 \cell -\pard\intbl\qc\fs16 104.00 \cell -\pard\intbl\qc\fs16 117.00 \cell +\pard\intbl\qc\fs16 01-708-1348 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 28JUL2013 \cell +\pard\intbl\qc\fs16 79 / Female / Multiple \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 78.0 \cell +\pard\intbl\qc\fs16 66.0 \cell +\pard\intbl\qc\fs16 115.00 \cell +\pard\intbl\qc\fs16 74.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1372 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 03APR2013 \cell -\pard\intbl\qc\fs16 84 / M / Not reported \cell -\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 01-708-1353 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17JUN2013 \cell +\pard\intbl\qc\fs16 87 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell \pard\intbl\qc\fs16 134.0 \cell \pard\intbl\qc\fs16 10.0 \cell \pard\intbl\qc\fs16 80.00 \cell @@ -1147,48 +1147,74 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1406 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 06DEC2013 \cell -\pard\intbl\qc\fs16 71 / F / Not reported \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 64.0 \cell -\pard\intbl\qc\fs16 10.0 \cell -\pard\intbl\qc\fs16 135.00 \cell -\pard\intbl\qc\fs16 61.00 \cell +\pard\intbl\qc\fs16 01-708-1428 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 02NOV2013 \cell +\pard\intbl\qc\fs16 84 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 98.0 \cell +\pard\intbl\qc\fs16 99.0 \cell +\pard\intbl\qc\fs16 127.00 \cell +\pard\intbl\qc\fs16 90.00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1007 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 21JUL2012 \cell +\pard\intbl\qc\fs16 54 / Female / Other \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 129.0 \cell +\pard\intbl\qc\fs16 138.0 \cell +\pard\intbl\qc\fs16 25.00 \cell +\pard\intbl\qc\fs16 88.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1029 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 10DEC2012 \cell -\pard\intbl\qc\fs16 82 / M / Other \cell +\pard\intbl\qc\fs16 01-709-1020 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 22NOV2012 \cell +\pard\intbl\qc\fs16 72 / Female / Other \cell \pard\intbl\qc\fs16 Not reported \cell \pard\intbl\qc\fs16 138.0 \cell \pard\intbl\qc\fs16 1.0 \cell @@ -1199,49 +1225,49 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1099 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 14OCT2013 \cell -\pard\intbl\qc\fs16 79 / F / Multiple \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 138.0 \cell -\pard\intbl\qc\fs16 47.0 \cell -\pard\intbl\qc\fs16 137.00 \cell -\pard\intbl\qc\fs16 50.00 \cell +\pard\intbl\qc\fs16 01-709-1081 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 09JAN2014 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 147.0 \cell +\pard\intbl\qc\fs16 54.0 \cell +\pard\intbl\qc\fs16 143.00 \cell +\pard\intbl\qc\fs16 43.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1168 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 25JUL2013 \cell -\pard\intbl\qc\fs16 72 / F / American Indian or Alaska Native \cell -\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 01-709-1102 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 07JAN2013 \cell +\pard\intbl\qc\fs16 71 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell \pard\intbl\qc\fs16 141.0 \cell \pard\intbl\qc\fs16 28.0 \cell \pard\intbl\qc\fs16 5.00 \cell @@ -1251,75 +1277,75 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1238 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 02MAY2013 \cell -\pard\intbl\qc\fs16 69 / M / White \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 92.0 \cell -\pard\intbl\qc\fs16 106.0 \cell -\pard\intbl\qc\fs16 100.00 \cell -\pard\intbl\qc\fs16 59.00 \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 16FEB2013 \cell +\pard\intbl\qc\fs16 77 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 66.0 \cell +\pard\intbl\qc\fs16 111.0 \cell +\pard\intbl\qc\fs16 80.00 \cell +\pard\intbl\qc\fs16 45.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1309 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 09JUN2013 \cell -\pard\intbl\qc\fs16 65 / M / American Indian or Alaska Native \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 87.0 \cell -\pard\intbl\qc\fs16 59.0 \cell -\pard\intbl\qc\fs16 23.00 \cell -\pard\intbl\qc\fs16 21.00 \cell +\pard\intbl\qc\fs16 01-709-1285 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17MAR2013 \cell +\pard\intbl\qc\fs16 87 / Male / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 150.0 \cell +\pard\intbl\qc\fs16 82.0 \cell +\pard\intbl\qc\fs16 75.00 \cell +\pard\intbl\qc\fs16 54.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1329 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 01AUG2013 \cell -\pard\intbl\qc\fs16 70 / M / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 01-709-1326 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 21MAR2013 \cell +\pard\intbl\qc\fs16 75 / Female / Other \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell \pard\intbl\qc\fs16 41.0 \cell \pard\intbl\qc\fs16 24.0 \cell \pard\intbl\qc\fs16 73.00 \cell @@ -1329,49 +1355,23 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1424 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 15FEB2013 \cell -\pard\intbl\qc\fs16 77 / M / Other \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 7.0 \cell -\pard\intbl\qc\fs16 18.0 \cell -\pard\intbl\qc\fs16 150.00 \cell -\pard\intbl\qc\fs16 99.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1006 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 27JAN2013 \cell -\pard\intbl\qc\fs16 77 / M / Asian \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 01-710-1002 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 30DEC2013 \cell +\pard\intbl\qc\fs16 88 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Not reported \cell \pard\intbl\qc\fs16 38.0 \cell \pard\intbl\qc\fs16 10.0 \cell \pard\intbl\qc\fs16 54.00 \cell @@ -1381,152 +1381,126 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1021 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 19SEP2013 \cell -\pard\intbl\qc\fs16 79 / M / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 95.0 \cell -\pard\intbl\qc\fs16 142.0 \cell -\pard\intbl\qc\fs16 85.00 \cell -\pard\intbl\qc\fs16 65.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1070 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 28AUG2012 \cell -\pard\intbl\qc\fs16 85 / F / Unknown \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 21.0 \cell -\pard\intbl\qc\fs16 104.0 \cell -\pard\intbl\qc\fs16 72.00 \cell -\pard\intbl\qc\fs16 55.00 \cell +\pard\intbl\qc\fs16 01-710-1045 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 20MAY2013 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 57.0 \cell +\pard\intbl\qc\fs16 138.0 \cell +\pard\intbl\qc\fs16 94.00 \cell +\pard\intbl\qc\fs16 102.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1137 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 03OCT2013 \cell -\pard\intbl\qc\fs16 79 / F / Multiple \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 63.0 \cell -\pard\intbl\qc\fs16 101.0 \cell -\pard\intbl\qc\fs16 59.00 \cell -\pard\intbl\qc\fs16 55.00 \cell +\pard\intbl\qc\fs16 01-710-1053 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 15DEC2012 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 55.0 \cell +\pard\intbl\qc\fs16 32.0 \cell +\pard\intbl\qc\fs16 19.00 \cell +\pard\intbl\qc\fs16 93.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1142 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 12SEP2012 \cell -\pard\intbl\qc\fs16 76 / F / Not reported \cell +\pard\intbl\qc\fs16 01-710-1154 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 08MAR2014 \cell +\pard\intbl\qc\fs16 84 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 23.0 \cell -\pard\intbl\qc\fs16 88.0 \cell -\pard\intbl\qc\fs16 4.00 \cell -\pard\intbl\qc\fs16 25.00 \cell +\pard\intbl\qc\fs16 119.0 \cell +\pard\intbl\qc\fs16 139.0 \cell +\pard\intbl\qc\fs16 87.00 \cell +\pard\intbl\qc\fs16 9.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1187 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 26OCT2012 \cell -\pard\intbl\qc\fs16 78 / F / Unknown \cell +\pard\intbl\qc\fs16 01-710-1166 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 10NOV2012 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell \pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 85.0 \cell -\pard\intbl\qc\fs16 130.0 \cell -\pard\intbl\qc\fs16 67.00 \cell -\pard\intbl\qc\fs16 50.00 \cell +\pard\intbl\qc\fs16 73.0 \cell +\pard\intbl\qc\fs16 79.0 \cell +\pard\intbl\qc\fs16 61.00 \cell +\pard\intbl\qc\fs16 37.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1249 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 19DEC2013 \cell -\pard\intbl\qc\fs16 79 / M / Not reported \cell +\pard\intbl\qc\fs16 01-710-1235 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 13SEP2012 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell \pard\intbl\qc\fs16 Not Hispanic or Latino \cell \pard\intbl\qc\fs16 136.0 \cell \pard\intbl\qc\fs16 61.0 \cell @@ -1537,75 +1511,101 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1278 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 13DEC2012 \cell -\pard\intbl\qc\fs16 81 / M / Asian \cell +\pard\intbl\qc\fs16 01-710-1270 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 01FEB2014 \cell +\pard\intbl\qc\fs16 83 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 25.0 \cell -\pard\intbl\qc\fs16 119.0 \cell -\pard\intbl\qc\fs16 28.00 \cell -\pard\intbl\qc\fs16 76.00 \cell +\pard\intbl\qc\fs16 34.0 \cell +\pard\intbl\qc\fs16 20.0 \cell +\pard\intbl\qc\fs16 38.00 \cell +\pard\intbl\qc\fs16 115.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1354 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 29OCT2012 \cell -\pard\intbl\qc\fs16 73 / M / Black or African American \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 53.0 \cell -\pard\intbl\qc\fs16 140.0 \cell -\pard\intbl\qc\fs16 69.00 \cell -\pard\intbl\qc\fs16 36.00 \cell +\pard\intbl\qc\fs16 01-710-1300 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 04DEC2012 \cell +\pard\intbl\qc\fs16 78 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 35.0 \cell +\pard\intbl\qc\fs16 120.0 \cell +\pard\intbl\qc\fs16 25.00 \cell +\pard\intbl\qc\fs16 37.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1408 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 26DEC2012 \cell -\pard\intbl\qc\fs16 80 / M / Multiple \cell +\pard\intbl\qc\fs16 01-710-1358 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 02SEP2012 \cell +\pard\intbl\qc\fs16 82 / Male / Asian \cell \pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 147.0 \cell +\pard\intbl\qc\fs16 32.0 \cell +\pard\intbl\qc\fs16 118.00 \cell +\pard\intbl\qc\fs16 122.00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1385 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 21OCT2012 \cell +\pard\intbl\qc\fs16 77 / Male / Multiple \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell \pard\intbl\qc\fs16 4.0 \cell \pard\intbl\qc\fs16 30.0 \cell \pard\intbl\qc\fs16 5.00 \cell @@ -1615,75 +1615,75 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-711-1012 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 20MAR2013 \cell -\pard\intbl\qc\fs16 67 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 76.0 \cell -\pard\intbl\qc\fs16 90.0 \cell -\pard\intbl\qc\fs16 56.00 \cell -\pard\intbl\qc\fs16 67.00 \cell +\pard\intbl\qc\fs16 01-711-1143 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 30MAR2013 \cell +\pard\intbl\qc\fs16 76 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 74.0 \cell +\pard\intbl\qc\fs16 113.0 \cell +\pard\intbl\qc\fs16 100.00 \cell +\pard\intbl\qc\fs16 53.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-711-1433 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 23JAN2013 \cell -\pard\intbl\qc\fs16 84 / F / Asian \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 85.0 \cell -\pard\intbl\qc\fs16 33.0 \cell -\pard\intbl\qc\fs16 89.00 \cell -\pard\intbl\qc\fs16 29.00 \cell +\pard\intbl\qc\fs16 01-713-1043 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17AUG2013 \cell +\pard\intbl\qc\fs16 78 / Female / Multiple \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 99.0 \cell +\pard\intbl\qc\fs16 53.0 \cell +\pard\intbl\qc\fs16 86.00 \cell +\pard\intbl\qc\fs16 16.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-713-1106 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 03OCT2012 \cell -\pard\intbl\qc\fs16 74 / M / Not reported \cell -\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 01-713-1073 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 15MAR2014 \cell +\pard\intbl\qc\fs16 74 / Female / Other \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell \pard\intbl\qc\fs16 24.0 \cell \pard\intbl\qc\fs16 66.0 \cell \pard\intbl\qc\fs16 130.00 \cell @@ -1693,75 +1693,75 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-713-1141 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 23MAY2013 \cell -\pard\intbl\qc\fs16 79 / M / White \cell -\pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 93.0 \cell -\pard\intbl\qc\fs16 88.0 \cell -\pard\intbl\qc\fs16 60.00 \cell -\pard\intbl\qc\fs16 73.00 \cell +\pard\intbl\qc\fs16 01-713-1448 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 05JAN2014 \cell +\pard\intbl\qc\fs16 71 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 75.0 \cell +\pard\intbl\qc\fs16 109.0 \cell +\pard\intbl\qc\fs16 112.00 \cell +\pard\intbl\qc\fs16 123.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-713-1209 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 16MAY2013 \cell -\pard\intbl\qc\fs16 77 / F / Black or African American \cell -\pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 127.0 \cell -\pard\intbl\qc\fs16 132.0 \cell -\pard\intbl\qc\fs16 63.00 \cell -\pard\intbl\qc\fs16 131.00 \cell +\pard\intbl\qc\fs16 01-714-1068 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 31JUL2013 \cell +\pard\intbl\qc\fs16 79 / Female / Other \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 70.0 \cell +\pard\intbl\qc\fs16 97.0 \cell +\pard\intbl\qc\fs16 7.00 \cell +\pard\intbl\qc\fs16 47.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-714-1288 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 24NOV2013 \cell -\pard\intbl\qc\fs16 77 / M / Multiple \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 01-714-1195 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 16APR2013 \cell +\pard\intbl\qc\fs16 75 / Male / Asian \cell +\pard\intbl\qc\fs16 Not reported \cell \pard\intbl\qc\fs16 109.0 \cell \pard\intbl\qc\fs16 16.0 \cell \pard\intbl\qc\fs16 11.00 \cell @@ -1771,308 +1771,308 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-714-1425 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 11AUG2013 \cell -\pard\intbl\qc\fs16 81 / M / Black or African American \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 124.0 \cell -\pard\intbl\qc\fs16 13.0 \cell -\pard\intbl\qc\fs16 4.00 \cell -\pard\intbl\qc\fs16 81.00 \cell +\pard\intbl\qc\fs16 01-715-1085 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 03FEB2013 \cell +\pard\intbl\qc\fs16 77 / Female / Other \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 128.0 \cell +\pard\intbl\qc\fs16 137.0 \cell +\pard\intbl\qc\fs16 49.00 \cell +\pard\intbl\qc\fs16 71.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-715-1319 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 03FEB2013 \cell -\pard\intbl\qc\fs16 65 / M / Multiple \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 102.0 \cell -\pard\intbl\qc\fs16 103.0 \cell -\pard\intbl\qc\fs16 110.00 \cell -\pard\intbl\qc\fs16 60.00 \cell +\pard\intbl\qc\fs16 01-715-1107 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 12FEB2013 \cell +\pard\intbl\qc\fs16 65 / Male / Asian \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 9.0 \cell +\pard\intbl\qc\fs16 124.0 \cell +\pard\intbl\qc\fs16 132.00 \cell +\pard\intbl\qc\fs16 59.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-715-1321 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 06FEB2014 \cell -\pard\intbl\qc\fs16 75 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 79.0 \cell -\pard\intbl\qc\fs16 32.0 \cell -\pard\intbl\qc\fs16 30.00 \cell -\pard\intbl\qc\fs16 61.00 \cell +\pard\intbl\qc\fs16 01-715-1405 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 27JUN2013 \cell +\pard\intbl\qc\fs16 69 / Male / Unknown \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 77.0 \cell +\pard\intbl\qc\fs16 80.0 \cell +\pard\intbl\qc\fs16 8.00 \cell +\pard\intbl\qc\fs16 69.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1030 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 25DEC2013 \cell -\pard\intbl\qc\fs16 83 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-716-1063 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 06MAY2013 \cell +\pard\intbl\qc\fs16 80 / Male / Asian \cell \pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 47.0 \cell -\pard\intbl\qc\fs16 13.0 \cell -\pard\intbl\qc\fs16 100.00 \cell -\pard\intbl\qc\fs16 71.00 \cell +\pard\intbl\qc\fs16 128.0 \cell +\pard\intbl\qc\fs16 20.0 \cell +\pard\intbl\qc\fs16 120.00 \cell +\pard\intbl\qc\fs16 6.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1071 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 03JUN2013 \cell -\pard\intbl\qc\fs16 78 / F / Black or African American \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 128.0 \cell -\pard\intbl\qc\fs16 20.0 \cell -\pard\intbl\qc\fs16 120.00 \cell -\pard\intbl\qc\fs16 6.00 \cell +\pard\intbl\qc\fs16 01-716-1094 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 16DEC2012 \cell +\pard\intbl\qc\fs16 82 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 114.0 \cell +\pard\intbl\qc\fs16 5.0 \cell +\pard\intbl\qc\fs16 140.00 \cell +\pard\intbl\qc\fs16 83.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1189 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 07OCT2012 \cell -\pard\intbl\qc\fs16 81 / M / Asian \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 145.0 \cell -\pard\intbl\qc\fs16 119.0 \cell -\pard\intbl\qc\fs16 68.00 \cell -\pard\intbl\qc\fs16 141.00 \cell +\pard\intbl\qc\fs16 01-716-1103 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 18MAR2014 \cell +\pard\intbl\qc\fs16 79 / Male / Multiple \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 140.0 \cell +\pard\intbl\qc\fs16 68.0 \cell +\pard\intbl\qc\fs16 46.00 \cell +\pard\intbl\qc\fs16 139.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1229 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 14FEB2013 \cell -\pard\intbl\qc\fs16 73 / F / Asian \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 107.0 \cell -\pard\intbl\qc\fs16 29.0 \cell -\pard\intbl\qc\fs16 89.00 \cell -\pard\intbl\qc\fs16 73.00 \cell +\pard\intbl\qc\fs16 01-716-1151 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 23JAN2013 \cell +\pard\intbl\qc\fs16 83 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 78.0 \cell +\pard\intbl\qc\fs16 106.0 \cell +\pard\intbl\qc\fs16 92.00 \cell +\pard\intbl\qc\fs16 72.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1364 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 27JUN2013 \cell -\pard\intbl\qc\fs16 84 / F / Unknown \cell +\pard\intbl\qc\fs16 01-716-1157 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 23SEP2013 \cell +\pard\intbl\qc\fs16 85 / Male / Asian \cell \pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 10.0 \cell -\pard\intbl\qc\fs16 69.0 \cell -\pard\intbl\qc\fs16 45.00 \cell -\pard\intbl\qc\fs16 96.00 \cell +\pard\intbl\qc\fs16 76.0 \cell +\pard\intbl\qc\fs16 77.0 \cell +\pard\intbl\qc\fs16 8.00 \cell +\pard\intbl\qc\fs16 33.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1373 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 24NOV2012 \cell -\pard\intbl\qc\fs16 74 / M / American Indian or Alaska Native \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 50.0 \cell -\pard\intbl\qc\fs16 41.0 \cell -\pard\intbl\qc\fs16 76.00 \cell -\pard\intbl\qc\fs16 87.00 \cell +\pard\intbl\qc\fs16 01-716-1167 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 30SEP2012 \cell +\pard\intbl\qc\fs16 68 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell +\pard\intbl\qc\fs16 118.0 \cell +\pard\intbl\qc\fs16 68.0 \cell +\pard\intbl\qc\fs16 47.00 \cell +\pard\intbl\qc\fs16 75.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1418 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 27APR2013 \cell -\pard\intbl\qc\fs16 80 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 15.0 \cell -\pard\intbl\qc\fs16 19.0 \cell -\pard\intbl\qc\fs16 125.00 \cell -\pard\intbl\qc\fs16 145.00 \cell +\pard\intbl\qc\fs16 01-716-1298 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 04APR2013 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 35.0 \cell +\pard\intbl\qc\fs16 67.0 \cell +\pard\intbl\qc\fs16 58.00 \cell +\pard\intbl\qc\fs16 73.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1447 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 10DEC2013 \cell -\pard\intbl\qc\fs16 72 / F / Unknown \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 10.0 \cell -\pard\intbl\qc\fs16 39.0 \cell -\pard\intbl\qc\fs16 147.00 \cell -\pard\intbl\qc\fs16 15.00 \cell +\pard\intbl\qc\fs16 01-716-1311 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 08MAY2014 \cell +\pard\intbl\qc\fs16 78 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 2.0 \cell +\pard\intbl\qc\fs16 91.0 \cell +\pard\intbl\qc\fs16 56.00 \cell +\pard\intbl\qc\fs16 32.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-717-1109 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 20JAN2014 \cell -\pard\intbl\qc\fs16 84 / M / Asian \cell +\pard\intbl\qc\fs16 01-717-1004 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 01JAN2014 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell \pard\intbl\qc\fs16 Not reported \cell \pard\intbl\qc\fs16 100.0 \cell \pard\intbl\qc\fs16 57.0 \cell @@ -2083,75 +2083,75 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-717-1174 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 16JAN2013 \cell -\pard\intbl\qc\fs16 73 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-717-1446 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 20AUG2013 \cell +\pard\intbl\qc\fs16 75 / Female / Unknown \cell \pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 149.0 \cell -\pard\intbl\qc\fs16 82.0 \cell -\pard\intbl\qc\fs16 135.00 \cell -\pard\intbl\qc\fs16 91.00 \cell +\pard\intbl\qc\fs16 95.0 \cell +\pard\intbl\qc\fs16 66.0 \cell +\pard\intbl\qc\fs16 80.00 \cell +\pard\intbl\qc\fs16 56.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-717-1357 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 21APR2013 \cell -\pard\intbl\qc\fs16 77 / M / White \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 114.0 \cell -\pard\intbl\qc\fs16 75.0 \cell -\pard\intbl\qc\fs16 20.00 \cell -\pard\intbl\qc\fs16 70.00 \cell +\pard\intbl\qc\fs16 01-718-1066 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 28JUN2013 \cell +\pard\intbl\qc\fs16 79 / Female / Asian \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 61.0 \cell +\pard\intbl\qc\fs16 47.0 \cell +\pard\intbl\qc\fs16 111.00 \cell +\pard\intbl\qc\fs16 121.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1101 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 01FEB2013 \cell -\pard\intbl\qc\fs16 82 / M / Asian \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 01-718-1079 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 11SEP2012 \cell +\pard\intbl\qc\fs16 67 / Female / White \cell +\pard\intbl\qc\fs16 Hispanic or Latino \cell \pard\intbl\qc\fs16 90.0 \cell \pard\intbl\qc\fs16 19.0 \cell \pard\intbl\qc\fs16 60.00 \cell @@ -2161,101 +2161,101 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1328 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 28JAN2013 \cell -\pard\intbl\qc\fs16 86 / M / Not reported \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 68.0 \cell -\pard\intbl\qc\fs16 58.0 \cell -\pard\intbl\qc\fs16 131.00 \cell -\pard\intbl\qc\fs16 16.00 \cell +\pard\intbl\qc\fs16 01-718-1170 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 25AUG2013 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 122.0 \cell +\pard\intbl\qc\fs16 80.0 \cell +\pard\intbl\qc\fs16 80.00 \cell +\pard\intbl\qc\fs16 45.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1371 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 11APR2013 \cell -\pard\intbl\qc\fs16 69 / F / Unknown \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 22.0 \cell -\pard\intbl\qc\fs16 136.0 \cell -\pard\intbl\qc\fs16 1.00 \cell -\pard\intbl\qc\fs16 85.00 \cell +\pard\intbl\qc\fs16 01-718-1250 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 21AUG2013 \cell +\pard\intbl\qc\fs16 82 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 29.0 \cell +\pard\intbl\qc\fs16 144.0 \cell +\pard\intbl\qc\fs16 101.00 \cell +\pard\intbl\qc\fs16 88.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1427 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 13DEC2012 \cell -\pard\intbl\qc\fs16 74 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-718-1254 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 28JUN2013 \cell +\pard\intbl\qc\fs16 78 / Male / Unknown \cell \pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 20.0 \cell -\pard\intbl\qc\fs16 30.0 \cell -\pard\intbl\qc\fs16 134.00 \cell -\pard\intbl\qc\fs16 24.00 \cell +\pard\intbl\qc\fs16 68.0 \cell +\pard\intbl\qc\fs16 58.0 \cell +\pard\intbl\qc\fs16 131.00 \cell +\pard\intbl\qc\fs16 16.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 01-701-1033 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 10MAR2014 \cell -\pard\intbl\qc\fs16 74 / M / Multiple \cell -\pard\intbl\qc\fs16 Not reported \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1028 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 11JUL2013 \cell +\pard\intbl\qc\fs16 71 / Male / Asian \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell \pard\intbl\qc\fs16 63.0 \cell \pard\intbl\qc\fs16 31.0 \cell \pard\intbl\qc\fs16 14.00 \cell @@ -2265,335 +2265,335 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1097 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 23DEC2013 \cell -\pard\intbl\qc\fs16 68 / M / Other \cell +\pard\intbl\qc\fs16 01-701-1034 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 24JUN2014 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell \pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 17.0 \cell -\pard\intbl\qc\fs16 34.0 \cell -\pard\intbl\qc\fs16 4.00 \cell -\pard\intbl\qc\fs16 107.00 \cell +\pard\intbl\qc\fs16 1.0 \cell +\pard\intbl\qc\fs16 14.0 \cell +\pard\intbl\qc\fs16 35.00 \cell +\pard\intbl\qc\fs16 144.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1111 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 25AUG2012 \cell -\pard\intbl\qc\fs16 81 / F / White \cell -\pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 3.0 \cell -\pard\intbl\qc\fs16 54.0 \cell -\pard\intbl\qc\fs16 80.00 \cell -\pard\intbl\qc\fs16 92.00 \cell +\pard\intbl\qc\fs16 01-701-1133 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 23OCT2012 \cell +\pard\intbl\qc\fs16 81 / Female / Other \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 71.0 \cell +\pard\intbl\qc\fs16 12.0 \cell +\pard\intbl\qc\fs16 74.00 \cell +\pard\intbl\qc\fs16 149.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1115 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 23NOV2012 \cell -\pard\intbl\qc\fs16 84 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-701-1146 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 07MAY2013 \cell +\pard\intbl\qc\fs16 75 / Female / Unknown \cell \pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 105.0 \cell -\pard\intbl\qc\fs16 124.0 \cell -\pard\intbl\qc\fs16 129.00 \cell -\pard\intbl\qc\fs16 52.00 \cell +\pard\intbl\qc\fs16 10.0 \cell +\pard\intbl\qc\fs16 126.0 \cell +\pard\intbl\qc\fs16 14.00 \cell +\pard\intbl\qc\fs16 64.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1188 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 03FEB2013 \cell -\pard\intbl\qc\fs16 71 / M / White \cell -\pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 88.0 \cell -\pard\intbl\qc\fs16 53.0 \cell -\pard\intbl\qc\fs16 27.00 \cell -\pard\intbl\qc\fs16 52.00 \cell +\pard\intbl\qc\fs16 01-701-1148 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 14AUG2013 \cell +\pard\intbl\qc\fs16 57 / Male / Not reported \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 78.0 \cell +\pard\intbl\qc\fs16 24.0 \cell +\pard\intbl\qc\fs16 86.00 \cell +\pard\intbl\qc\fs16 4.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1192 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 08JUL2012 \cell -\pard\intbl\qc\fs16 80 / F / Not reported \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell -\pard\intbl\qc\fs16 35.0 \cell -\pard\intbl\qc\fs16 23.0 \cell -\pard\intbl\qc\fs16 133.00 \cell -\pard\intbl\qc\fs16 22.00 \cell +\pard\intbl\qc\fs16 01-701-1180 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 28JAN2013 \cell +\pard\intbl\qc\fs16 56 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 107.0 \cell +\pard\intbl\qc\fs16 36.0 \cell +\pard\intbl\qc\fs16 137.00 \cell +\pard\intbl\qc\fs16 31.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1211 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 30OCT2012 \cell -\pard\intbl\qc\fs16 76 / F / Other \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 6.0 \cell -\pard\intbl\qc\fs16 108.0 \cell -\pard\intbl\qc\fs16 146.00 \cell -\pard\intbl\qc\fs16 57.00 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 26NOV2013 \cell +\pard\intbl\qc\fs16 79 / Female / Not reported \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 88.0 \cell +\pard\intbl\qc\fs16 53.0 \cell +\pard\intbl\qc\fs16 27.00 \cell +\pard\intbl\qc\fs16 52.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1294 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 17MAR2013 \cell -\pard\intbl\qc\fs16 67 / M / Other \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 67.0 \cell -\pard\intbl\qc\fs16 13.0 \cell -\pard\intbl\qc\fs16 129.00 \cell -\pard\intbl\qc\fs16 131.00 \cell +\pard\intbl\qc\fs16 01-701-1239 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 28DEC2013 \cell +\pard\intbl\qc\fs16 56 / Male / White \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 52.0 \cell +\pard\intbl\qc\fs16 39.0 \cell +\pard\intbl\qc\fs16 91.00 \cell +\pard\intbl\qc\fs16 24.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1317 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 10MAY2014 \cell -\pard\intbl\qc\fs16 68 / M / Unknown \cell -\pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 73.0 \cell -\pard\intbl\qc\fs16 25.0 \cell -\pard\intbl\qc\fs16 82.00 \cell -\pard\intbl\qc\fs16 38.00 \cell +\pard\intbl\qc\fs16 01-701-1275 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 25JAN2014 \cell +\pard\intbl\qc\fs16 61 / Male / White \cell +\pard\intbl\qc\fs16 Not reported \cell +\pard\intbl\qc\fs16 23.0 \cell +\pard\intbl\qc\fs16 71.0 \cell +\pard\intbl\qc\fs16 47.00 \cell +\pard\intbl\qc\fs16 29.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1324 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 16SEP2012 \cell -\pard\intbl\qc\fs16 79 / M / Asian \cell +\pard\intbl\qc\fs16 01-701-1287 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17JAN2014 \cell +\pard\intbl\qc\fs16 56 / Female / Multiple \cell \pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 92.0 \cell -\pard\intbl\qc\fs16 45.0 \cell -\pard\intbl\qc\fs16 30.00 \cell -\pard\intbl\qc\fs16 95.00 \cell +\pard\intbl\qc\fs16 67.0 \cell +\pard\intbl\qc\fs16 13.0 \cell +\pard\intbl\qc\fs16 129.00 \cell +\pard\intbl\qc\fs16 131.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1341 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 22DEC2012 \cell -\pard\intbl\qc\fs16 51 / M / American Indian or Alaska Native \cell -\pard\intbl\qc\fs16 Not reported \cell -\pard\intbl\qc\fs16 132.0 \cell -\pard\intbl\qc\fs16 22.0 \cell -\pard\intbl\qc\fs16 107.00 \cell -\pard\intbl\qc\fs16 125.00 \cell +\pard\intbl\qc\fs16 01-701-1302 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 20AUG2013 \cell +\pard\intbl\qc\fs16 61 / Male / Asian \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 10.0 \cell +\pard\intbl\qc\fs16 150.0 \cell +\pard\intbl\qc\fs16 101.00 \cell +\pard\intbl\qc\fs16 69.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1429 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 25FEB2013 \cell -\pard\intbl\qc\fs16 84 / F / American Indian or Alaska Native \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 71.0 \cell -\pard\intbl\qc\fs16 144.0 \cell -\pard\intbl\qc\fs16 103.00 \cell -\pard\intbl\qc\fs16 86.00 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 24JUL2013 \cell +\pard\intbl\qc\fs16 67 / Male / Multiple \cell +\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 73.0 \cell +\pard\intbl\qc\fs16 70.0 \cell +\pard\intbl\qc\fs16 55.00 \cell +\pard\intbl\qc\fs16 114.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1442 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 17OCT2013 \cell -\pard\intbl\qc\fs16 57 / F / Asian \cell +\pard\intbl\qc\fs16 01-701-1383 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 22JAN2013 \cell +\pard\intbl\qc\fs16 72 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Unknown \cell -\pard\intbl\qc\fs16 134.0 \cell -\pard\intbl\qc\fs16 108.0 \cell -\pard\intbl\qc\fs16 39.00 \cell -\pard\intbl\qc\fs16 45.00 \cell +\pard\intbl\qc\fs16 58.0 \cell +\pard\intbl\qc\fs16 75.0 \cell +\pard\intbl\qc\fs16 107.00 \cell +\pard\intbl\qc\fs16 123.00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-702-1082 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 03JUL2013 \cell -\pard\intbl\qc\fs16 84 / F / Asian \cell -\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 01-701-1444 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 31DEC2012 \cell +\pard\intbl\qc\fs16 63 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Unknown \cell \pard\intbl\qc\fs16 127.0 \cell \pard\intbl\qc\fs16 109.0 \cell \pard\intbl\qc\fs16 109.00 \cell @@ -2603,23 +2603,23 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1086 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 22AUG2012 \cell -\pard\intbl\qc\fs16 71 / M / Multiple \cell -\pard\intbl\qc\fs16 Unknown \cell +\pard\intbl\qc\fs16 01-703-1076 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17OCT2013 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell \pard\intbl\qc\fs16 78.0 \cell \pard\intbl\qc\fs16 79.0 \cell \pard\intbl\qc\fs16 129.00 \cell @@ -2629,42 +2629,42 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2095 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6106 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9092 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10429 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11008 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11543 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12167 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx970 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3880 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4619 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5404 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6466 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9561 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10346 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10946 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11500 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12147 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1119 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 02FEB2013 \cell -\pard\intbl\qc\fs16 81 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Hispanic or Latino \cell -\pard\intbl\qc\fs16 69.0 \cell -\pard\intbl\qc\fs16 132.0 \cell -\pard\intbl\qc\fs16 120.00 \cell -\pard\intbl\qc\fs16 121.00 \cell +\pard\intbl\qc\fs16 01-703-1258 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 10JUL2012 \cell +\pard\intbl\qc\fs16 78 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Not Hispanic or Latino \cell +\pard\intbl\qc\fs16 142.0 \cell +\pard\intbl\qc\fs16 5.0 \cell +\pard\intbl\qc\fs16 26.00 \cell +\pard\intbl\qc\fs16 41.00 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2095 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5081 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6106 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9092 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10429 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11008 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11543 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12167 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx970 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3880 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4619 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5404 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6466 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9561 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10346 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10946 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11500 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12147 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2681,16 +2681,16 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2095 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5081 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6106 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9092 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10429 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11008 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11543 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12167 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx970 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3880 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4619 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5404 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6466 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9561 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10346 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10946 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11500 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12147 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/lsidem02/lsidem02.rtf b/tests/testthat/_snaps/lsidem02/lsidem02.rtf old mode 100755 new mode 100644 index 2045b892..dcdc23ef --- a/tests/testthat/_snaps/lsidem02/lsidem02.rtf +++ b/tests/testthat/_snaps/lsidem02/lsidem02.rtf @@ -3,14 +3,14 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3423 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5315 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7432 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8603 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9594 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11755 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1147 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1880 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2660 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3852 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5044 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8345 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10546 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11738 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIDEM02:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -25,21 +25,21 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3423 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5315 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7432 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8603 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9594 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11755 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1147 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1880 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2660 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3852 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5044 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8345 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10546 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11738 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Region \cell \pard\intbl\qc\fs16 \keepn\trhdr Country / Territory \cell \pard\intbl\qc\fs16 \keepn\trhdr Randomization Date / Time \cell \pard\intbl\qc\fs16 \keepn\trhdr Randomization Number \cell -\pard\intbl\qc\fs16 \keepn\trhdr Stratification Factor 1 \cell -\pard\intbl\qc\fs16 \keepn\trhdr Stratification Factor 2 \cell +\pard\intbl\qc\fs16 \keepn\trhdr Description of Stratification Factor 1 \cell +\pard\intbl\qc\fs16 \keepn\trhdr Description of Stratification Factor 2 \cell \pard\intbl\qc\fs16 \keepn\trhdr Randomization Treatment Assignment \cell \pard\intbl\qc\fs16 \keepn\trhdr Actual Treatment \cell \row @@ -47,21 +47,21 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1023 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 05AUG2012 / 09:59 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1015 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 02JAN2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -69,21 +69,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1023 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 05AUG2012 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 19JUL2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 19JUL2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -91,21 +113,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1033 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 18MAR2014 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 18MAR2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -113,21 +135,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 01JUL2014 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 01JUL2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -135,21 +157,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1047 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 12FEB2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 12FEB2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -157,21 +179,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1111 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 07SEP2012 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 07SEP2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -179,21 +201,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1115 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 30NOV2012 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 30NOV2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -201,21 +223,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1118 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 12MAR2014 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1130 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 15FEB2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -223,43 +245,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1130 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 15FEB2014 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1133 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 28OCT2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Placebo \cell -\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1146 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 20MAY2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 20MAY2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -267,21 +289,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1148 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 23AUG2013 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1153 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 23SEP2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1180 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 12FEB2013 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -289,21 +333,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1181 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 05DEC2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 05DEC2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -311,21 +355,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1188 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 15FEB2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 15FEB2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -333,21 +377,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1192 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 22JUL2012 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 22JUL2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -355,21 +399,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1203 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 02FEB2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 02FEB2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -377,21 +421,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1211 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 15NOV2012 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 15NOV2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -399,43 +443,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1239 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 11JAN2014 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1234 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 30MAR2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1275 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 07FEB2014 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1239 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 11JAN2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -443,21 +487,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1287 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 25JAN2014 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1275 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 07FEB2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -465,43 +509,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1294 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 24MAR2013 / 10:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1302 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 29AUG2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 29AUG2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -509,21 +531,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1317 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 22MAY2014 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 22MAY2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -531,21 +553,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1324 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 02OCT2012 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 02OCT2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -553,21 +575,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1341 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 05JAN2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 05JAN2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -575,21 +597,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1345 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 08OCT2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 08OCT2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -597,87 +619,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1360 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 31JUL2013 / 09:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1363 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 30MAY2013 / 09:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Placebo \cell -\pard\intbl\qc\fs16 Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1383 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 04FEB2013 / 10:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1387 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 12MAR2014 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 12MAR2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -685,21 +641,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1392 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 28OCT2012 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 28OCT2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -707,21 +663,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1415 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 23SEP2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 23SEP2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -729,21 +685,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1429 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 19MAR2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 19MAR2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -751,21 +707,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1440 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 08AUG2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 08AUG2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -773,87 +729,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1442 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 26OCT2013 / 09:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-701-1444 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 05JAN2013 / 10:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-702-1082 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 26JUL2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 05JAN2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1076 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 25OCT2013 / 09:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -861,21 +751,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1096 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 25JAN2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1042 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 02MAR2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -883,21 +773,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1100 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 13MAR2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1096 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 25JAN2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -905,43 +795,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1119 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 20FEB2013 / 10:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1175 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 20DEC2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1100 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 13MAR2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -949,21 +817,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1182 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 17OCT2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17OCT2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -971,21 +839,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1197 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 16JUN2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 16JUN2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -993,21 +861,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1210 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 16MAR2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 16MAR2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -1015,43 +883,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1258 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 20JUL2012 / 09:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1279 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 13MAY2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 13MAY2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1059,65 +905,65 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1299 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 12SEP2012 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1295 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 21NOV2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Placebo \cell -\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1335 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 17MAR2014 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1299 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 12SEP2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1379 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 22SEP2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 22SEP2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1125,21 +971,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1403 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 12DEC2012 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 12DEC2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1147,21 +993,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1008 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 13JAN2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-703-1439 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 12MAR2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -1169,21 +1015,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1009 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 27AUG2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 27AUG2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1191,65 +1037,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1017 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 06OCT2013 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1010 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 21FEB2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1025 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 27SEP2013 / 09:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1065 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 24OCT2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 24OCT2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -1257,43 +1081,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1074 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 22JAN2014 / 10:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1093 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 15MAR2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 15MAR2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -1301,21 +1103,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1114 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 23JAN2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1135 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 31OCT2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1323,21 +1125,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1120 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 02DEC2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 19NOV2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1345,87 +1147,87 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1127 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 02OCT2013 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1241 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 25AUG2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Placebo \cell -\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1135 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 31OCT2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1260 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 30AUG2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1164 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 19SEP2012 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1266 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 13OCT2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Placebo \cell -\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1218 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 19NOV2012 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 08JUL2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1433,21 +1235,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1233 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 21MAR2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1388 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 07DEC2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -1455,21 +1257,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1260 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 30AUG2012 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1435 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17NOV2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -1477,43 +1279,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1266 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 13OCT2013 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1018 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 05JUL2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1325 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 23APR2014 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 27NOV2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1521,43 +1323,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1388 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 07DEC2012 / 10:59 \cell -\pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Placebo \cell -\pard\intbl\qc\fs16 Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-704-1435 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 17NOV2012 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1059 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 05AUG2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -1565,21 +1345,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1059 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 05AUG2013 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1186 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 08JAN2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -1587,21 +1367,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1199 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 16SEP2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 16SEP2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1609,21 +1389,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1280 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 17JAN2014 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 17JAN2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -1631,21 +1411,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1281 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 28NOV2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 28NOV2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -1653,21 +1433,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1282 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 26DEC2012 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 26DEC2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -1675,43 +1455,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1292 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 14OCT2013 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1303 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 16DEC2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1303 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 16DEC2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1377 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 04JAN2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -1719,87 +1499,87 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1310 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 02NOV2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1431 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 23JUN2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1382 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 13MAY2013 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-706-1041 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 31DEC2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-705-1393 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 07SEP2012 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-706-1049 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 14MAY2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-706-1384 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 15SEP2012 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 15SEP2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1807,43 +1587,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-707-1206 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 28OCT2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 20DEC2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Placebo \cell -\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1019 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 20DEC2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 20DEC2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1851,21 +1631,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1032 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 09FEB2013 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 09FEB2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1873,65 +1653,87 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1213 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 09FEB2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1084 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 09MAY2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1216 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 24OCT2012 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1158 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 08FEB2014 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1171 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 06DEC2012 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1236 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 21SEP2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 21SEP2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -1939,43 +1741,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1272 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 06FEB2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1253 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 07MAY2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1286 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 10SEP2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 10SEP2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -1983,65 +1785,65 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1297 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 25JAN2013 / 10:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1296 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 14JUN2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1316 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 23AUG2013 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 25JAN2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell -\pard\intbl\qc\fs16 Placebo \cell -\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1336 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 07DEC2012 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 07DEC2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -2049,21 +1851,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1342 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 29DEC2012 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 29DEC2012 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -2071,21 +1873,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1347 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 20APR2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 20APR2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \row @@ -2093,21 +1895,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1348 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 05AUG2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 05AUG2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -2115,21 +1917,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1353 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 04JUL2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 04JUL2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -2137,21 +1939,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1372 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 12APR2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 12APR2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell \pard\intbl\qc\fs16 Xanomeline High Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -2159,21 +1961,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-708-1378 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 03SEP2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 03SEP2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -2181,21 +1983,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1001 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 08OCT2013 / 09:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 08OCT2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -2203,21 +2005,131 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1020 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 01DEC2012 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1029 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 25DEC2012 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1081 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 18JAN2014 / 10:59 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 18JAN2014 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1099 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 25OCT2013 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1102 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 15JAN2013 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 04MAR2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \pard\intbl\qc\fs16 Xanomeline Low Dose \cell \row @@ -2225,21 +2137,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3423 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5315 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7432 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8603 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9594 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11755 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1088 \cell -\pard\intbl\qc\fs16 North America \cell -\pard\intbl\qc\fs16 United States of America \cell -\pard\intbl\qc\fs16 12APR2014 / 09:59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1238 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 15MAY2013 / 11:59 \cell \pard\intbl\qc\fs16 1000001 \cell -\pard\intbl\qc\fs16 Stratification Factor 1 \cell -\pard\intbl\qc\fs16 Stratification Factor 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1259 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 26JAN2013 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell \pard\intbl\qc\fs16 Placebo \cell \pard\intbl\qc\fs16 Placebo \cell \row @@ -2247,14 +2181,80 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3423 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5315 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7432 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8603 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9594 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10584 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11755 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1285 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 24MAR2013 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1306 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 03FEB2014 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1147 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1880 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2660 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3852 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5044 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8345 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10546 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11738 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 01-709-1309 \cell +\pard\intbl\qc\fs16 Northern America \cell +\pard\intbl\qc\fs16 United States \cell +\pard\intbl\qc\fs16 19JUN2013 / 11:59 \cell +\pard\intbl\qc\fs16 1000001 \cell +\pard\intbl\qc\fs16 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs16 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1147 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1880 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2660 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3852 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5044 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8345 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10546 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11738 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2269,14 +2269,14 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3423 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5315 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7432 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8603 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9594 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11755 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1147 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1880 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2660 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3852 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5044 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8345 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10546 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11738 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/lsidev01/lsidev01.rtf b/tests/testthat/_snaps/lsidev01/lsidev01.rtf new file mode 100644 index 00000000..4bd872c0 --- /dev/null +++ b/tests/testthat/_snaps/lsidev01/lsidev01.rtf @@ -0,0 +1,1742 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx714 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1070 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2006 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2585 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4769 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5526 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6373 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9537 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIDEV01:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx714 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1070 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2006 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2585 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4769 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5526 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6373 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9537 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Region \cell +\pard\intbl\qc\fs16 \keepn\trhdr Site ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell +\pard\intbl\qc\fs16 \keepn\trhdr Start Date of Deviation \cell +\pard\intbl\qc\fs16 \keepn\trhdr Study Day\super a\nosupersub of Start of Deviation \cell +\pard\intbl\qc\fs16 \keepn\trhdr Protocol Deviation Category \cell +\pard\intbl\qc\fs16 \keepn\trhdr Protocol Deviation Verbatim Term \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Northern America \cell +\pard\intbl\qc\fs16 701 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1097 \cell +\pard\intbl\qc\fs16 68 / Male / Other \cell +\pard\intbl\qc\fs16 2014-03-18 \cell +\pard\intbl\qc\fs16 77 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2014-06-30 \cell +\pard\intbl\qc\fs16 181 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell +\pard\intbl\qc\fs16 2012-11-29 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 67 / Male / Other \cell +\pard\intbl\qc\fs16 2013-05-03 \cell +\pard\intbl\qc\fs16 41 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 67 / Male / Multiple \cell +\pard\intbl\qc\fs16 2013-08-07 \cell +\pard\intbl\qc\fs16 8 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 84 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 2013-03-28 \cell +\pard\intbl\qc\fs16 10 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1148 \cell +\pard\intbl\qc\fs16 57 / Male / Not reported \cell +\pard\intbl\qc\fs16 2013-09-12 \cell +\pard\intbl\qc\fs16 21 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2014-01-31 \cell +\pard\intbl\qc\fs16 162 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1239 \cell +\pard\intbl\qc\fs16 56 / Male / White \cell +\pard\intbl\qc\fs16 2014-02-19 \cell +\pard\intbl\qc\fs16 40 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1383 \cell +\pard\intbl\qc\fs16 72 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 2013-06-18 \cell +\pard\intbl\qc\fs16 135 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1444 \cell +\pard\intbl\qc\fs16 63 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 2013-01-14 \cell +\pard\intbl\qc\fs16 10 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 703 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 84 / Male / Other \cell +\pard\intbl\qc\fs16 2013-11-09 \cell +\pard\intbl\qc\fs16 24 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-703-1258 \cell +\pard\intbl\qc\fs16 78 / Female / Black or African American \cell +\pard\intbl\qc\fs16 2012-08-15 \cell +\pard\intbl\qc\fs16 27 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2012-08-17 \cell +\pard\intbl\qc\fs16 29 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-703-1042 \cell +\pard\intbl\qc\fs16 64 / Male / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 2013-03-20 \cell +\pard\intbl\qc\fs16 19 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2013-04-25 \cell +\pard\intbl\qc\fs16 55 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 704 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 77 / Male / Multiple \cell +\pard\intbl\qc\fs16 2013-05-12 \cell +\pard\intbl\qc\fs16 110 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1135 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 2014-01-04 \cell +\pard\intbl\qc\fs16 66 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2014-04-10 \cell +\pard\intbl\qc\fs16 162 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 81 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 2013-01-16 \cell +\pard\intbl\qc\fs16 59 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-704-1241 \cell +\pard\intbl\qc\fs16 86 / Male / Not reported \cell +\pard\intbl\qc\fs16 2013-10-12 \cell +\pard\intbl\qc\fs16 49 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2013-10-16 \cell +\pard\intbl\qc\fs16 53 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1266 \cell +\pard\intbl\qc\fs16 82 / Male / Multiple \cell +\pard\intbl\qc\fs16 2013-10-20 \cell +\pard\intbl\qc\fs16 8 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1332 \cell +\pard\intbl\qc\fs16 80 / Male / Multiple \cell +\pard\intbl\qc\fs16 2014-02-11 \cell +\pard\intbl\qc\fs16 65 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-704-1010 \cell +\pard\intbl\qc\fs16 80 / Male / Black or African American \cell +\pard\intbl\qc\fs16 2014-07-06 \cell +\pard\intbl\qc\fs16 136 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 705 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 87 / Male / Black or African American \cell +\pard\intbl\qc\fs16 2013-09-17 \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2013-09-27 \cell +\pard\intbl\qc\fs16 12 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-705-1382 \cell +\pard\intbl\qc\fs16 82 / Male / Multiple \cell +\pard\intbl\qc\fs16 2013-05-13 \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-705-1280 \cell +\pard\intbl\qc\fs16 56 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 2014-02-20 \cell +\pard\intbl\qc\fs16 35 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2014-03-18 \cell +\pard\intbl\qc\fs16 61 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2014-05-20 \cell +\pard\intbl\qc\fs16 124 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-705-1281 \cell +\pard\intbl\qc\fs16 73 / Female / Not reported \cell +\pard\intbl\qc\fs16 2014-02-21 \cell +\pard\intbl\qc\fs16 86 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-705-1349 \cell +\pard\intbl\qc\fs16 86 / Female / Other \cell +\pard\intbl\qc\fs16 2013-05-23 \cell +\pard\intbl\qc\fs16 75 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 706 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-706-1049 \cell +\pard\intbl\qc\fs16 60 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 2013-05-16 \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 708 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-708-1084 \cell +\pard\intbl\qc\fs16 73 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 2013-08-25 \cell +\pard\intbl\qc\fs16 109 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 82 / Male / Not reported \cell +\pard\intbl\qc\fs16 2013-03-22 \cell +\pard\intbl\qc\fs16 45 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2013-03-28 \cell +\pard\intbl\qc\fs16 51 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-708-1253 \cell +\pard\intbl\qc\fs16 61 / Male / Not reported \cell +\pard\intbl\qc\fs16 2013-10-26 \cell +\pard\intbl\qc\fs16 173 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 709 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 77 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 2013-04-22 \cell +\pard\intbl\qc\fs16 50 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-709-1029 \cell +\pard\intbl\qc\fs16 82 / Male / Other \cell +\pard\intbl\qc\fs16 2013-01-10 \cell +\pard\intbl\qc\fs16 17 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-709-1088 \cell +\pard\intbl\qc\fs16 69 / Male / Not reported \cell +\pard\intbl\qc\fs16 2014-07-05 \cell +\pard\intbl\qc\fs16 85 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2014-08-06 \cell +\pard\intbl\qc\fs16 117 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2014-09-19 \cell +\pard\intbl\qc\fs16 161 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-709-1259 \cell +\pard\intbl\qc\fs16 82 / Male / Other \cell +\pard\intbl\qc\fs16 2013-02-14 \cell +\pard\intbl\qc\fs16 20 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 710 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-710-1002 \cell +\pard\intbl\qc\fs16 88 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 2014-01-14 \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2014-01-17 \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-710-1154 \cell +\pard\intbl\qc\fs16 84 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 2014-05-04 \cell +\pard\intbl\qc\fs16 37 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-710-1235 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 2012-12-22 \cell +\pard\intbl\qc\fs16 88 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2013-01-25 \cell +\pard\intbl\qc\fs16 122 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-710-1021 \cell +\pard\intbl\qc\fs16 79 / Male / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 2013-10-13 \cell +\pard\intbl\qc\fs16 17 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2013-10-28 \cell +\pard\intbl\qc\fs16 32 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-710-1137 \cell +\pard\intbl\qc\fs16 79 / Female / Multiple \cell +\pard\intbl\qc\fs16 2013-10-24 \cell +\pard\intbl\qc\fs16 14 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-710-1187 \cell +\pard\intbl\qc\fs16 78 / Female / Unknown \cell +\pard\intbl\qc\fs16 2013-01-07 \cell +\pard\intbl\qc\fs16 59 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-710-1278 \cell +\pard\intbl\qc\fs16 81 / Male / Asian \cell +\pard\intbl\qc\fs16 2013-02-12 \cell +\pard\intbl\qc\fs16 51 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-710-1354 \cell +\pard\intbl\qc\fs16 73 / Male / Black or African American \cell +\pard\intbl\qc\fs16 2013-01-10 \cell +\pard\intbl\qc\fs16 61 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-710-1060 \cell +\pard\intbl\qc\fs16 82 / Male / Other \cell +\pard\intbl\qc\fs16 2013-03-12 \cell +\pard\intbl\qc\fs16 71 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 711 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-711-1036 \cell +\pard\intbl\qc\fs16 70 / Male / Not reported \cell +\pard\intbl\qc\fs16 2012-09-03 \cell +\pard\intbl\qc\fs16 37 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 713 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-713-1043 \cell +\pard\intbl\qc\fs16 78 / Female / Multiple \cell +\pard\intbl\qc\fs16 2014-03-21 \cell +\pard\intbl\qc\fs16 188 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-713-1269 \cell +\pard\intbl\qc\fs16 73 / Male / White \cell +\pard\intbl\qc\fs16 2014-03-12 \cell +\pard\intbl\qc\fs16 45 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 714 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-714-1035 \cell +\pard\intbl\qc\fs16 88 / Female / Black or African American \cell +\pard\intbl\qc\fs16 2014-06-18 \cell +\pard\intbl\qc\fs16 63 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 715 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-715-1405 \cell +\pard\intbl\qc\fs16 69 / Male / Unknown \cell +\pard\intbl\qc\fs16 2013-07-08 \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs16 Developed withdrawal criteria but not withdrawn \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-715-1319 \cell +\pard\intbl\qc\fs16 65 / Male / Multiple \cell +\pard\intbl\qc\fs16 2013-02-19 \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2013-03-06 \cell +\pard\intbl\qc\fs16 18 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 716 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-716-1094 \cell +\pard\intbl\qc\fs16 82 / Male / Black or African American \cell +\pard\intbl\qc\fs16 2013-01-13 \cell +\pard\intbl\qc\fs16 26 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-716-1157 \cell +\pard\intbl\qc\fs16 85 / Male / Asian \cell +\pard\intbl\qc\fs16 2014-01-04 \cell +\pard\intbl\qc\fs16 95 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2014-01-06 \cell +\pard\intbl\qc\fs16 97 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-716-1311 \cell +\pard\intbl\qc\fs16 78 / Male / Black or African American \cell +\pard\intbl\qc\fs16 2014-07-13 \cell +\pard\intbl\qc\fs16 61 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-716-1447 \cell +\pard\intbl\qc\fs16 72 / Female / Unknown \cell +\pard\intbl\qc\fs16 2014-06-08 \cell +\pard\intbl\qc\fs16 175 \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs16 Received a disallowed concomitant treatment \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-716-1024 \cell +\pard\intbl\qc\fs16 87 / Female / Asian \cell +\pard\intbl\qc\fs16 2012-11-04 \cell +\pard\intbl\qc\fs16 119 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-716-1177 \cell +\pard\intbl\qc\fs16 72 / Male / White \cell +\pard\intbl\qc\fs16 2014-12-24 \cell +\pard\intbl\qc\fs16 114 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 718 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-718-1079 \cell +\pard\intbl\qc\fs16 67 / Female / White \cell +\pard\intbl\qc\fs16 2012-10-20 \cell +\pard\intbl\qc\fs16 32 \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs16 Entered but did not satisfy criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-718-1250 \cell +\pard\intbl\qc\fs16 82 / Female / Black or African American \cell +\pard\intbl\qc\fs16 2013-09-22 \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2013-10-04 \cell +\pard\intbl\qc\fs16 14 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-718-1101 \cell +\pard\intbl\qc\fs16 82 / Male / Asian \cell +\pard\intbl\qc\fs16 2013-07-30 \cell +\pard\intbl\qc\fs16 164 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4769 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5526 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9537 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-718-1427 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 2013-02-12 \cell +\pard\intbl\qc\fs16 58 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx714 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1070 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2006 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2585 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4769 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5526 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6373 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9537 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4769 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9537 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} +\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} +} \ No newline at end of file diff --git a/tests/testthat/_snaps/lsidev02/lsidev02.rtf b/tests/testthat/_snaps/lsidev02/lsidev02.rtf new file mode 100644 index 00000000..8e67b1fe --- /dev/null +++ b/tests/testthat/_snaps/lsidev02/lsidev02.rtf @@ -0,0 +1,400 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx714 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1070 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2006 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2585 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4992 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5883 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6730 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9715 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIDEV02:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx714 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1070 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2006 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2585 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4992 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5883 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6730 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9715 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Region \cell +\pard\intbl\qc\fs16 \keepn\trhdr Site ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell +\pard\intbl\qc\fs16 \keepn\trhdr Start Date of Deviation \cell +\pard\intbl\qc\fs16 \keepn\trhdr Study Day\super a\nosupersub of Start of Deviation \cell +\pard\intbl\qc\fs16 \keepn\trhdr Protocol Deviation Category \cell +\pard\intbl\qc\fs16 \keepn\trhdr Protocol Deviation Verbatim Term \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Northern America \cell +\pard\intbl\qc\fs16 701 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 67 / Male / Other \cell +\pard\intbl\qc\fs16 2013-05-03 \cell +\pard\intbl\qc\fs16 41 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1148 \cell +\pard\intbl\qc\fs16 57 / Male / Not reported \cell +\pard\intbl\qc\fs16 2014-01-31 \cell +\pard\intbl\qc\fs16 162 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 703 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-703-1042 \cell +\pard\intbl\qc\fs16 64 / Male / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 2013-04-25 \cell +\pard\intbl\qc\fs16 55 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 704 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-704-1135 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 2014-04-10 \cell +\pard\intbl\qc\fs16 162 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 81 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 2013-01-16 \cell +\pard\intbl\qc\fs16 59 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 705 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-705-1281 \cell +\pard\intbl\qc\fs16 73 / Female / Not reported \cell +\pard\intbl\qc\fs16 2014-02-21 \cell +\pard\intbl\qc\fs16 86 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 709 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-709-1088 \cell +\pard\intbl\qc\fs16 69 / Male / Not reported \cell +\pard\intbl\qc\fs16 2014-08-06 \cell +\pard\intbl\qc\fs16 117 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2014-09-19 \cell +\pard\intbl\qc\fs16 161 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 716 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-716-1157 \cell +\pard\intbl\qc\fs16 85 / Male / Asian \cell +\pard\intbl\qc\fs16 2014-01-04 \cell +\pard\intbl\qc\fs16 95 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-716-1311 \cell +\pard\intbl\qc\fs16 78 / Male / Black or African American \cell +\pard\intbl\qc\fs16 2014-07-13 \cell +\pard\intbl\qc\fs16 61 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-716-1024 \cell +\pard\intbl\qc\fs16 87 / Female / Asian \cell +\pard\intbl\qc\fs16 2012-11-04 \cell +\pard\intbl\qc\fs16 119 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 718 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-718-1250 \cell +\pard\intbl\qc\fs16 82 / Female / Black or African American \cell +\pard\intbl\qc\fs16 2013-10-04 \cell +\pard\intbl\qc\fs16 14 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-718-1101 \cell +\pard\intbl\qc\fs16 82 / Male / Asian \cell +\pard\intbl\qc\fs16 2013-07-30 \cell +\pard\intbl\qc\fs16 164 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx714 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1070 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2006 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2585 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4992 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5883 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6730 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9715 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-718-1427 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 2013-02-12 \cell +\pard\intbl\qc\fs16 58 \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs16 Received wrong treatment or incorrect dose \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx714 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1070 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2006 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2585 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4992 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5883 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6730 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9715 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx714 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1070 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2006 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2585 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4992 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5883 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6730 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9715 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} +\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} +} \ No newline at end of file diff --git a/tests/testthat/_snaps/lsidev03/lsidev03.rtf b/tests/testthat/_snaps/lsidev03/lsidev03.rtf new file mode 100644 index 00000000..c6193725 --- /dev/null +++ b/tests/testthat/_snaps/lsidev03/lsidev03.rtf @@ -0,0 +1,850 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx742 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1113 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2086 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5007 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8112 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9457 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIDEV03:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx742 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1113 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2086 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5007 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8112 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9457 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Region \cell +\pard\intbl\qc\fs16 \keepn\trhdr Site ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell +\pard\intbl\qc\fs16 \keepn\trhdr Inclusion / Exclusion Criterion Number \cell +\pard\intbl\qc\fs16 \keepn\trhdr Inclusion / Exclusion Description \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Northern America \cell +\pard\intbl\qc\fs16 701 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / Multiple \cell +\pard\intbl\qc\fs16 INC02 \cell +\pard\intbl\qc\fs16 Medication criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell +\pard\intbl\qc\fs16 INC03 \cell +\pard\intbl\qc\fs16 Laboratory criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 68 / Male / Unknown \cell +\pard\intbl\qc\fs16 EXC02 \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 67 / Male / Multiple \cell +\pard\intbl\qc\fs16 EXC02 \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1133 \cell +\pard\intbl\qc\fs16 81 / Female / Other \cell +\pard\intbl\qc\fs16 INC01 \cell +\pard\intbl\qc\fs16 Disease criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1148 \cell +\pard\intbl\qc\fs16 57 / Male / Not reported \cell +\pard\intbl\qc\fs16 EXC02 \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1302 \cell +\pard\intbl\qc\fs16 61 / Male / Asian \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-701-1234 \cell +\pard\intbl\qc\fs16 69 / Male / Not reported \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 703 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-703-1258 \cell +\pard\intbl\qc\fs16 78 / Female / Black or African American \cell +\pard\intbl\qc\fs16 EXC02 \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 704 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 81 / Female / Asian \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 71 / Female / Black or African American \cell +\pard\intbl\qc\fs16 INC02 \cell +\pard\intbl\qc\fs16 Medication criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 68 / Female / Not reported \cell +\pard\intbl\qc\fs16 INC03 \cell +\pard\intbl\qc\fs16 Laboratory criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 68 / Female / Not reported \cell +\pard\intbl\qc\fs16 EXC02 \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 INC02 \cell +\pard\intbl\qc\fs16 Medication criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-704-1008 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 INC02 \cell +\pard\intbl\qc\fs16 Medication criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1074 \cell +\pard\intbl\qc\fs16 80 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 EXC02 \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-704-1233 \cell +\pard\intbl\qc\fs16 87 / Female / Not reported \cell +\pard\intbl\qc\fs16 INC01 \cell +\pard\intbl\qc\fs16 Disease criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1388 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 705 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-705-1292 \cell +\pard\intbl\qc\fs16 60 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 INC02 \cell +\pard\intbl\qc\fs16 Medication criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 706 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-706-1041 \cell +\pard\intbl\qc\fs16 64 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 INC03 \cell +\pard\intbl\qc\fs16 Laboratory criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 708 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 82 / Male / Not reported \cell +\pard\intbl\qc\fs16 INC01 \cell +\pard\intbl\qc\fs16 Disease criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-708-1353 \cell +\pard\intbl\qc\fs16 87 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 EXC02 \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 87 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-708-1171 \cell +\pard\intbl\qc\fs16 77 / Female / Unknown \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 709 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-709-1007 \cell +\pard\intbl\qc\fs16 54 / Female / Other \cell +\pard\intbl\qc\fs16 EXC02 \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-709-1168 \cell +\pard\intbl\qc\fs16 72 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 INC01 \cell +\pard\intbl\qc\fs16 Disease criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-709-1339 \cell +\pard\intbl\qc\fs16 81 / Male / Black or African American \cell +\pard\intbl\qc\fs16 INC03 \cell +\pard\intbl\qc\fs16 Laboratory criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 710 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-710-1166 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-710-1354 \cell +\pard\intbl\qc\fs16 73 / Male / Black or African American \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-710-1408 \cell +\pard\intbl\qc\fs16 80 / Male / Multiple \cell +\pard\intbl\qc\fs16 INC02 \cell +\pard\intbl\qc\fs16 Medication criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-710-1315 \cell +\pard\intbl\qc\fs16 83 / Female / Unknown \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 713 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-713-1179 \cell +\pard\intbl\qc\fs16 64 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 714 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-714-1035 \cell +\pard\intbl\qc\fs16 88 / Female / Black or African American \cell +\pard\intbl\qc\fs16 INC01 \cell +\pard\intbl\qc\fs16 Disease criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-714-1375 \cell +\pard\intbl\qc\fs16 78 / Female / Black or African American \cell +\pard\intbl\qc\fs16 INC02 \cell +\pard\intbl\qc\fs16 Medication criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 715 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-715-1405 \cell +\pard\intbl\qc\fs16 69 / Male / Unknown \cell +\pard\intbl\qc\fs16 INC01 \cell +\pard\intbl\qc\fs16 Disease criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 716 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-716-1298 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 EXC02 \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-716-1044 \cell +\pard\intbl\qc\fs16 74 / Male / Not reported \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 717 \cell +\pard\intbl\qc\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-717-1201 \cell +\pard\intbl\qc\fs16 85 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 INC02 \cell +\pard\intbl\qc\fs16 Medication criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 718 \cell +\pard\intbl\qc\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-718-1066 \cell +\pard\intbl\qc\fs16 79 / Female / Asian \cell +\pard\intbl\qc\fs16 EXC01 \cell +\pard\intbl\qc\fs16 Medical history criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-718-1170 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell +\pard\intbl\qc\fs16 EXC02 \cell +\pard\intbl\qc\fs16 Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-718-1427 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 INC03 \cell +\pard\intbl\qc\fs16 Laboratory criteria \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx742 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1113 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2086 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5007 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8112 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9457 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 INC01 \cell +\pard\intbl\qc\fs16 Disease criteria \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx742 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1113 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2086 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5007 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8112 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9457 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx742 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1113 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2086 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5007 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9457 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} +\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} +} \ No newline at end of file diff --git a/tests/testthat/_snaps/lsids01/lsids01.rtf b/tests/testthat/_snaps/lsids01/lsids01.rtf old mode 100755 new mode 100644 index 5bf49b60..1c333076 --- a/tests/testthat/_snaps/lsids01/lsids01.rtf +++ b/tests/testthat/_snaps/lsids01/lsids01.rtf @@ -4,12 +4,12 @@ { \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2630 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5616 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6641 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8245 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9493 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10295 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2050 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5036 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6061 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7666 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9136 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10027 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11498 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIDS01:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -26,21 +26,21 @@ { \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2630 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5616 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6641 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8245 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9493 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10295 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2050 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5036 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6061 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7666 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9136 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10027 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11498 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell \pard\intbl\qc\fs16 \keepn\trhdr Study Agent Discontinued \cell \pard\intbl\qc\fs16 \keepn\trhdr Last Visit\super a\nosupersub \cell -\pard\intbl\qc\fs16 \keepn\trhdr Study Day\super b\nosupersub of Last Study Agent Administered \cell -\pard\intbl\qc\fs16 \keepn\trhdr Total Dose (unit)\super c\nosupersub \cell -\pard\intbl\qc\fs16 \keepn\trhdr Date of Discontinuation \cell +\pard\intbl\qc\fs16 \keepn\trhdr Date of Last Study Agent Administered (Study Day\super b\nosupersub ) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Cumulative Dose (unit) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Date of Discontinuation (Study Day\super b\nosupersub ) \cell \pard\intbl\qc\fs16 \keepn\trhdr Primary Reason for Discontinuation \cell \row } @@ -48,241 +48,241 @@ { \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1146 \cell -\pard\intbl\qc\fs16 75 / F / Unknown \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 682 [unit] \cell -\pard\intbl\qc\fs16 30JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 31MAR2014 (400) \cell +\pard\intbl\qc\fs16 2039 mg \cell +\pard\intbl\qc\fs16 14APR2014 (28) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1180 \cell -\pard\intbl\qc\fs16 56 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 678 [unit] \cell -\pard\intbl\qc\fs16 23MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 23JAN2013 (200) \cell +\pard\intbl\qc\fs16 1296 mg \cell +\pard\intbl\qc\fs16 23JAN2013 (55) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1181 \cell -\pard\intbl\qc\fs16 79 / F / Not reported \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 3375 [unit] \cell -\pard\intbl\qc\fs16 12DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 24MAR2013 (50) \cell +\pard\intbl\qc\fs16 4786 mg \cell +\pard\intbl\qc\fs16 25MAR2013 (39) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1302 \cell -\pard\intbl\qc\fs16 61 / M / Asian \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1285 [unit] \cell -\pard\intbl\qc\fs16 05NOV2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 12JAN2013 (200) \cell +\pard\intbl\qc\fs16 4810 mg \cell +\pard\intbl\qc\fs16 14JAN2013 (61) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1360 \cell -\pard\intbl\qc\fs16 67 / M / Multiple \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 84 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 3744 [unit] \cell -\pard\intbl\qc\fs16 14AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 30APR2013 (100) \cell +\pard\intbl\qc\fs16 2242 mg \cell +\pard\intbl\qc\fs16 30APR2013 (43) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1444 \cell -\pard\intbl\qc\fs16 63 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-703-1086 \cell +\pard\intbl\qc\fs16 71 / Male / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3217 [unit] \cell -\pard\intbl\qc\fs16 13FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 04DEC2012 (300) \cell +\pard\intbl\qc\fs16 984 mg \cell +\pard\intbl\qc\fs16 24DEC2012 (114) \cell +\pard\intbl\qc\fs16 Death \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1076 \cell -\pard\intbl\qc\fs16 69 / M / White \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 81 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4866 [unit] \cell -\pard\intbl\qc\fs16 24DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 13JUN2013 (100) \cell +\pard\intbl\qc\fs16 4461 mg \cell +\pard\intbl\qc\fs16 13JUN2013 (114) \cell +\pard\intbl\qc\fs16 Death \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1258 \cell -\pard\intbl\qc\fs16 78 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 84 / Male / Other \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4920 [unit] \cell -\pard\intbl\qc\fs16 21JAN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 11DEC2013 (100) \cell +\pard\intbl\qc\fs16 2020 mg \cell +\pard\intbl\qc\fs16 12DEC2013 (57) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1295 \cell -\pard\intbl\qc\fs16 88 / F / Other \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4285 [unit] \cell -\pard\intbl\qc\fs16 19MAY2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 29JUN2013 (300) \cell +\pard\intbl\qc\fs16 4525 mg \cell +\pard\intbl\qc\fs16 22JUL2013 (37) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1335 \cell -\pard\intbl\qc\fs16 67 / F / Not reported \cell +\pard\intbl\qc\fs16 01-703-1279 \cell +\pard\intbl\qc\fs16 72 / Female / Unknown \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4144 [unit] \cell -\pard\intbl\qc\fs16 24MAY2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 03JUN2013 (50) \cell +\pard\intbl\qc\fs16 2467 mg \cell +\pard\intbl\qc\fs16 22JUN2013 (41) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1403 \cell -\pard\intbl\qc\fs16 67 / M / Multiple \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 81 / Female / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4799 [unit] \cell -\pard\intbl\qc\fs16 19DEC2012 \cell +\pard\intbl\qc\fs16 24OCT2013 (50) \cell +\pard\intbl\qc\fs16 1715 mg \cell +\pard\intbl\qc\fs16 29NOV2013 (64) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -290,417 +290,417 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1017 \cell -\pard\intbl\qc\fs16 77 / M / Asian \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 77 / Male / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 1561 [unit] \cell -\pard\intbl\qc\fs16 24NOV2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 07JUL2013 (100) \cell +\pard\intbl\qc\fs16 2240 mg \cell +\pard\intbl\qc\fs16 08JUL2013 (167) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1065 \cell -\pard\intbl\qc\fs16 75 / M / Multiple \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 71 / Female / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4487 [unit] \cell -\pard\intbl\qc\fs16 24DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01FEB2014 (400) \cell +\pard\intbl\qc\fs16 4108 mg \cell +\pard\intbl\qc\fs16 03FEB2014 (64) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1093 \cell -\pard\intbl\qc\fs16 79 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 68 / Female / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1035 [unit] \cell -\pard\intbl\qc\fs16 20JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 05AUG2013 (400) \cell +\pard\intbl\qc\fs16 1570 mg \cell +\pard\intbl\qc\fs16 08AUG2013 (32) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1241 \cell -\pard\intbl\qc\fs16 86 / M / Not reported \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2698 [unit] \cell -\pard\intbl\qc\fs16 31OCT2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 04JUL2014 (400) \cell +\pard\intbl\qc\fs16 3769 mg \cell +\pard\intbl\qc\fs16 06AUG2014 (106) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1266 \cell -\pard\intbl\qc\fs16 82 / M / Multiple \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 87 / Male / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3347 [unit] \cell -\pard\intbl\qc\fs16 06DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 28SEP2013 (300) \cell +\pard\intbl\qc\fs16 4284 mg \cell +\pard\intbl\qc\fs16 29SEP2013 (14) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1332 \cell -\pard\intbl\qc\fs16 80 / M / Multiple \cell +\pard\intbl\qc\fs16 01-705-1393 \cell +\pard\intbl\qc\fs16 84 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 3812 [unit] \cell -\pard\intbl\qc\fs16 16FEB2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01FEB2013 (100) \cell +\pard\intbl\qc\fs16 1908 mg \cell +\pard\intbl\qc\fs16 20FEB2013 (167) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1281 \cell -\pard\intbl\qc\fs16 73 / F / Not reported \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 72 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4016 [unit] \cell -\pard\intbl\qc\fs16 17MAR2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 24DEC2013 (200) \cell +\pard\intbl\qc\fs16 596 mg \cell +\pard\intbl\qc\fs16 08JAN2014 (20) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1303 \cell -\pard\intbl\qc\fs16 72 / M / Unknown \cell +\pard\intbl\qc\fs16 01-708-1019 \cell +\pard\intbl\qc\fs16 68 / Male / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4880 [unit] \cell -\pard\intbl\qc\fs16 02JUN2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01JAN2014 (100) \cell +\pard\intbl\qc\fs16 2506 mg \cell +\pard\intbl\qc\fs16 23JAN2014 (35) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1310 \cell -\pard\intbl\qc\fs16 74 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 82 / Male / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2580 [unit] \cell -\pard\intbl\qc\fs16 23JAN2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 22MAR2013 (200) \cell +\pard\intbl\qc\fs16 4143 mg \cell +\pard\intbl\qc\fs16 04APR2013 (58) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1377 \cell -\pard\intbl\qc\fs16 63 / F / Unknown \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 61 / Male / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 2996 [unit] \cell -\pard\intbl\qc\fs16 07MAR2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 03MAY2013 (200) \cell +\pard\intbl\qc\fs16 3599 mg \cell +\pard\intbl\qc\fs16 08MAY2013 (104) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-706-1049 \cell -\pard\intbl\qc\fs16 60 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-708-1428 \cell +\pard\intbl\qc\fs16 84 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2178 [unit] \cell -\pard\intbl\qc\fs16 25JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 14DEC2013 (200) \cell +\pard\intbl\qc\fs16 2605 mg \cell +\pard\intbl\qc\fs16 31JAN2014 (84) \cell +\pard\intbl\qc\fs16 Death \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1178 \cell -\pard\intbl\qc\fs16 77 / F / Unknown \cell +\pard\intbl\qc\fs16 01-709-1007 \cell +\pard\intbl\qc\fs16 54 / Female / Other \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 261 [unit] \cell -\pard\intbl\qc\fs16 06APR2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 28AUG2012 (50) \cell +\pard\intbl\qc\fs16 1063 mg \cell +\pard\intbl\qc\fs16 01SEP2012 (33) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1216 \cell -\pard\intbl\qc\fs16 78 / M / Asian \cell +\pard\intbl\qc\fs16 01-709-1081 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 4138 [unit] \cell -\pard\intbl\qc\fs16 06DEC2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 27APR2014 (100) \cell +\pard\intbl\qc\fs16 418 mg \cell +\pard\intbl\qc\fs16 10MAY2014 (113) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1236 \cell -\pard\intbl\qc\fs16 86 / F / White \cell +\pard\intbl\qc\fs16 01-709-1102 \cell +\pard\intbl\qc\fs16 71 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3262 [unit] \cell -\pard\intbl\qc\fs16 26SEP2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 27MAR2013 (400) \cell +\pard\intbl\qc\fs16 1302 mg \cell +\pard\intbl\qc\fs16 31MAR2013 (76) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1372 \cell -\pard\intbl\qc\fs16 84 / M / Not reported \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 77 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1322 [unit] \cell -\pard\intbl\qc\fs16 10MAY2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 11JUN2013 (400) \cell +\pard\intbl\qc\fs16 198 mg \cell +\pard\intbl\qc\fs16 25JUN2013 (114) \cell +\pard\intbl\qc\fs16 Death \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1168 \cell -\pard\intbl\qc\fs16 72 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-709-1285 \cell +\pard\intbl\qc\fs16 87 / Male / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 572 [unit] \cell -\pard\intbl\qc\fs16 27SEP2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 23MAY2013 (300) \cell +\pard\intbl\qc\fs16 345 mg \cell +\pard\intbl\qc\fs16 31MAY2013 (69) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1238 \cell -\pard\intbl\qc\fs16 69 / M / White \cell +\pard\intbl\qc\fs16 01-710-1002 \cell +\pard\intbl\qc\fs16 88 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2329 [unit] \cell -\pard\intbl\qc\fs16 07AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18JAN2014 (300) \cell +\pard\intbl\qc\fs16 191 mg \cell +\pard\intbl\qc\fs16 18JAN2014 (5) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1329 \cell -\pard\intbl\qc\fs16 70 / M / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-710-1045 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 756 [unit] \cell -\pard\intbl\qc\fs16 29AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 13AUG2013 (300) \cell +\pard\intbl\qc\fs16 1185 mg \cell +\pard\intbl\qc\fs16 17AUG2013 (76) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1424 \cell -\pard\intbl\qc\fs16 77 / M / Other \cell +\pard\intbl\qc\fs16 01-710-1053 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3553 [unit] \cell -\pard\intbl\qc\fs16 08MAR2013 \cell +\pard\intbl\qc\fs16 10FEB2013 (200) \cell +\pard\intbl\qc\fs16 2349 mg \cell +\pard\intbl\qc\fs16 15FEB2013 (52) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -708,109 +708,109 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1021 \cell -\pard\intbl\qc\fs16 79 / M / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-710-1154 \cell +\pard\intbl\qc\fs16 84 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1225 [unit] \cell -\pard\intbl\qc\fs16 12NOV2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 27APR2014 (50) \cell +\pard\intbl\qc\fs16 1166 mg \cell +\pard\intbl\qc\fs16 09MAY2014 (42) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1070 \cell -\pard\intbl\qc\fs16 85 / F / Unknown \cell +\pard\intbl\qc\fs16 01-710-1166 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 2619 [unit] \cell -\pard\intbl\qc\fs16 23FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 19MAR2013 (50) \cell +\pard\intbl\qc\fs16 3800 mg \cell +\pard\intbl\qc\fs16 30MAR2013 (121) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1137 \cell -\pard\intbl\qc\fs16 79 / F / Multiple \cell +\pard\intbl\qc\fs16 01-710-1300 \cell +\pard\intbl\qc\fs16 78 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4505 [unit] \cell -\pard\intbl\qc\fs16 13NOV2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 15FEB2013 (200) \cell +\pard\intbl\qc\fs16 1557 mg \cell +\pard\intbl\qc\fs16 19FEB2013 (67) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1142 \cell -\pard\intbl\qc\fs16 76 / F / Not reported \cell +\pard\intbl\qc\fs16 01-710-1358 \cell +\pard\intbl\qc\fs16 82 / Male / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1884 [unit] \cell -\pard\intbl\qc\fs16 23OCT2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 09FEB2013 (200) \cell +\pard\intbl\qc\fs16 3352 mg \cell +\pard\intbl\qc\fs16 12MAR2013 (177) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1278 \cell -\pard\intbl\qc\fs16 81 / M / Asian \cell +\pard\intbl\qc\fs16 01-711-1143 \cell +\pard\intbl\qc\fs16 76 / Female / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1435 [unit] \cell -\pard\intbl\qc\fs16 03MAR2013 \cell +\pard\intbl\qc\fs16 30MAY2013 (100) \cell +\pard\intbl\qc\fs16 2234 mg \cell +\pard\intbl\qc\fs16 01JUN2013 (60) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -818,21 +818,21 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-711-1012 \cell -\pard\intbl\qc\fs16 67 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-714-1068 \cell +\pard\intbl\qc\fs16 79 / Female / Other \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 1873 [unit] \cell -\pard\intbl\qc\fs16 02MAY2013 \cell +\pard\intbl\qc\fs16 08OCT2013 (100) \cell +\pard\intbl\qc\fs16 998 mg \cell +\pard\intbl\qc\fs16 16OCT2013 (70) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -840,43 +840,43 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-711-1433 \cell -\pard\intbl\qc\fs16 84 / F / Asian \cell +\pard\intbl\qc\fs16 01-715-1107 \cell +\pard\intbl\qc\fs16 65 / Male / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2045 [unit] \cell -\pard\intbl\qc\fs16 06FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 07MAY2013 (100) \cell +\pard\intbl\qc\fs16 2442 mg \cell +\pard\intbl\qc\fs16 13MAY2013 (77) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-713-1141 \cell -\pard\intbl\qc\fs16 79 / M / White \cell +\pard\intbl\qc\fs16 01-716-1063 \cell +\pard\intbl\qc\fs16 80 / Male / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2384 [unit] \cell -\pard\intbl\qc\fs16 06AUG2013 \cell +\pard\intbl\qc\fs16 25AUG2013 (50) \cell +\pard\intbl\qc\fs16 4962 mg \cell +\pard\intbl\qc\fs16 28AUG2013 (112) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -884,175 +884,175 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-714-1425 \cell -\pard\intbl\qc\fs16 81 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-716-1151 \cell +\pard\intbl\qc\fs16 83 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 3686 [unit] \cell -\pard\intbl\qc\fs16 22AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 11MAY2013 (50) \cell +\pard\intbl\qc\fs16 1976 mg \cell +\pard\intbl\qc\fs16 07JUN2013 (127) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-715-1319 \cell -\pard\intbl\qc\fs16 65 / M / Multiple \cell +\pard\intbl\qc\fs16 01-716-1311 \cell +\pard\intbl\qc\fs16 78 / Male / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3797 [unit] \cell -\pard\intbl\qc\fs16 18MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 21SEP2014 (300) \cell +\pard\intbl\qc\fs16 3451 mg \cell +\pard\intbl\qc\fs16 30SEP2014 (140) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-715-1321 \cell -\pard\intbl\qc\fs16 75 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-718-1066 \cell +\pard\intbl\qc\fs16 79 / Female / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1625 [unit] \cell -\pard\intbl\qc\fs16 22APR2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 16JUL2013 (100) \cell +\pard\intbl\qc\fs16 3281 mg \cell +\pard\intbl\qc\fs16 30JUL2013 (24) \cell +\pard\intbl\qc\fs16 Death \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1071 \cell -\pard\intbl\qc\fs16 78 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-718-1079 \cell +\pard\intbl\qc\fs16 67 / Female / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4590 [unit] \cell -\pard\intbl\qc\fs16 01AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 31OCT2012 (300) \cell +\pard\intbl\qc\fs16 3021 mg \cell +\pard\intbl\qc\fs16 06NOV2012 (49) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1229 \cell -\pard\intbl\qc\fs16 73 / F / Asian \cell +\pard\intbl\qc\fs16 01-718-1250 \cell +\pard\intbl\qc\fs16 82 / Female / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 3984 [unit] \cell -\pard\intbl\qc\fs16 02APR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 31JAN2014 (400) \cell +\pard\intbl\qc\fs16 1993 mg \cell +\pard\intbl\qc\fs16 08FEB2014 (141) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1373 \cell -\pard\intbl\qc\fs16 74 / M / American Indian or Alaska Native \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1146 \cell +\pard\intbl\qc\fs16 75 / Female / Unknown \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3481 [unit] \cell -\pard\intbl\qc\fs16 28FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 26JUN2013 (100) \cell +\pard\intbl\qc\fs16 607 mg \cell +\pard\intbl\qc\fs16 30JUN2013 (42) \cell +\pard\intbl\qc\fs16 Death \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-717-1357 \cell -\pard\intbl\qc\fs16 77 / M / White \cell +\pard\intbl\qc\fs16 01-701-1180 \cell +\pard\intbl\qc\fs16 56 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3353 [unit] \cell -\pard\intbl\qc\fs16 20OCT2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18MAR2013 (300) \cell +\pard\intbl\qc\fs16 853 mg \cell +\pard\intbl\qc\fs16 23MAR2013 (40) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1101 \cell -\pard\intbl\qc\fs16 82 / M / Asian \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 79 / Female / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 4406 [unit] \cell -\pard\intbl\qc\fs16 02AUG2013 \cell +\pard\intbl\qc\fs16 09DEC2013 (100) \cell +\pard\intbl\qc\fs16 4890 mg \cell +\pard\intbl\qc\fs16 12DEC2013 (8) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -1060,219 +1060,219 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1328 \cell -\pard\intbl\qc\fs16 86 / M / Not reported \cell +\pard\intbl\qc\fs16 01-701-1302 \cell +\pard\intbl\qc\fs16 61 / Male / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3352 [unit] \cell -\pard\intbl\qc\fs16 01MAY2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 05NOV2013 (300) \cell +\pard\intbl\qc\fs16 4945 mg \cell +\pard\intbl\qc\fs16 05NOV2013 (69) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1371 \cell -\pard\intbl\qc\fs16 69 / F / Unknown \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 67 / Male / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3454 [unit] \cell -\pard\intbl\qc\fs16 08AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 05AUG2013 (100) \cell +\pard\intbl\qc\fs16 3098 mg \cell +\pard\intbl\qc\fs16 14AUG2013 (15) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1427 \cell -\pard\intbl\qc\fs16 74 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-701-1444 \cell +\pard\intbl\qc\fs16 63 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 1061 [unit] \cell -\pard\intbl\qc\fs16 18FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 12FEB2013 (100) \cell +\pard\intbl\qc\fs16 1790 mg \cell +\pard\intbl\qc\fs16 13FEB2013 (40) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 01-701-1033 \cell -\pard\intbl\qc\fs16 74 / M / Multiple \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1076 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2167 [unit] \cell -\pard\intbl\qc\fs16 14APR2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 24DEC2013 (50) \cell +\pard\intbl\qc\fs16 2763 mg \cell +\pard\intbl\qc\fs16 24DEC2013 (61) \cell +\pard\intbl\qc\fs16 Death \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1115 \cell -\pard\intbl\qc\fs16 84 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-703-1258 \cell +\pard\intbl\qc\fs16 78 / Female / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3252 [unit] \cell -\pard\intbl\qc\fs16 23JAN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 11JAN2013 (300) \cell +\pard\intbl\qc\fs16 1938 mg \cell +\pard\intbl\qc\fs16 21JAN2013 (186) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1188 \cell -\pard\intbl\qc\fs16 71 / M / White \cell +\pard\intbl\qc\fs16 01-703-1295 \cell +\pard\intbl\qc\fs16 88 / Female / Other \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 933 [unit] \cell -\pard\intbl\qc\fs16 25MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 19APR2014 (100) \cell +\pard\intbl\qc\fs16 2629 mg \cell +\pard\intbl\qc\fs16 19MAY2014 (180) \cell +\pard\intbl\qc\fs16 Death \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1211 \cell -\pard\intbl\qc\fs16 76 / F / Other \cell +\pard\intbl\qc\fs16 01-703-1335 \cell +\pard\intbl\qc\fs16 67 / Female / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4245 [unit] \cell -\pard\intbl\qc\fs16 14JAN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 07MAY2014 (300) \cell +\pard\intbl\qc\fs16 1521 mg \cell +\pard\intbl\qc\fs16 24MAY2014 (69) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1429 \cell -\pard\intbl\qc\fs16 84 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-703-1403 \cell +\pard\intbl\qc\fs16 67 / Male / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2949 [unit] \cell -\pard\intbl\qc\fs16 30APR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 13DEC2012 (50) \cell +\pard\intbl\qc\fs16 2825 mg \cell +\pard\intbl\qc\fs16 19DEC2012 (8) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1086 \cell -\pard\intbl\qc\fs16 71 / M / Multiple \cell +\pard\intbl\qc\fs16 01-704-1017 \cell +\pard\intbl\qc\fs16 77 / Male / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2829 [unit] \cell -\pard\intbl\qc\fs16 24DEC2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18NOV2013 (50) \cell +\pard\intbl\qc\fs16 856 mg \cell +\pard\intbl\qc\fs16 24NOV2013 (50) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1119 \cell -\pard\intbl\qc\fs16 81 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-704-1065 \cell +\pard\intbl\qc\fs16 75 / Male / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 2288 [unit] \cell -\pard\intbl\qc\fs16 13JUN2013 \cell +\pard\intbl\qc\fs16 22DEC2013 (100) \cell +\pard\intbl\qc\fs16 3493 mg \cell +\pard\intbl\qc\fs16 24DEC2013 (62) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -1280,109 +1280,109 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1182 \cell -\pard\intbl\qc\fs16 84 / M / Other \cell +\pard\intbl\qc\fs16 01-704-1093 \cell +\pard\intbl\qc\fs16 79 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 2075 [unit] \cell -\pard\intbl\qc\fs16 12DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 17JUN2013 (300) \cell +\pard\intbl\qc\fs16 1177 mg \cell +\pard\intbl\qc\fs16 20JUN2013 (98) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1197 \cell -\pard\intbl\qc\fs16 76 / F / Other \cell +\pard\intbl\qc\fs16 01-704-1241 \cell +\pard\intbl\qc\fs16 86 / Male / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1716 [unit] \cell -\pard\intbl\qc\fs16 22JUL2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 09OCT2013 (50) \cell +\pard\intbl\qc\fs16 367 mg \cell +\pard\intbl\qc\fs16 31OCT2013 (68) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1279 \cell -\pard\intbl\qc\fs16 72 / F / Unknown \cell +\pard\intbl\qc\fs16 01-704-1266 \cell +\pard\intbl\qc\fs16 82 / Male / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 3288 [unit] \cell -\pard\intbl\qc\fs16 22JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 06DEC2013 (100) \cell +\pard\intbl\qc\fs16 4354 mg \cell +\pard\intbl\qc\fs16 06DEC2013 (55) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1025 \cell -\pard\intbl\qc\fs16 81 / F / Asian \cell +\pard\intbl\qc\fs16 01-704-1332 \cell +\pard\intbl\qc\fs16 80 / Male / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 958 [unit] \cell -\pard\intbl\qc\fs16 29NOV2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 14FEB2014 (200) \cell +\pard\intbl\qc\fs16 3148 mg \cell +\pard\intbl\qc\fs16 16FEB2014 (70) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1114 \cell -\pard\intbl\qc\fs16 77 / M / Multiple \cell +\pard\intbl\qc\fs16 01-705-1281 \cell +\pard\intbl\qc\fs16 73 / Female / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 967 [unit] \cell -\pard\intbl\qc\fs16 08JUL2013 \cell +\pard\intbl\qc\fs16 27FEB2014 (50) \cell +\pard\intbl\qc\fs16 4050 mg \cell +\pard\intbl\qc\fs16 17MAR2014 (110) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -1390,109 +1390,109 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1120 \cell -\pard\intbl\qc\fs16 71 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-705-1303 \cell +\pard\intbl\qc\fs16 72 / Male / Unknown \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4345 [unit] \cell -\pard\intbl\qc\fs16 03FEB2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 30DEC2013 (400) \cell +\pard\intbl\qc\fs16 3807 mg \cell +\pard\intbl\qc\fs16 02JUN2014 (169) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1323 \cell -\pard\intbl\qc\fs16 68 / F / Not reported \cell +\pard\intbl\qc\fs16 01-705-1310 \cell +\pard\intbl\qc\fs16 74 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1091 [unit] \cell -\pard\intbl\qc\fs16 08AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 23JAN2014 (200) \cell +\pard\intbl\qc\fs16 3630 mg \cell +\pard\intbl\qc\fs16 23JAN2014 (83) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1325 \cell -\pard\intbl\qc\fs16 81 / M / White \cell +\pard\intbl\qc\fs16 01-705-1377 \cell +\pard\intbl\qc\fs16 63 / Female / Unknown \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4663 [unit] \cell -\pard\intbl\qc\fs16 06AUG2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 25JAN2014 (400) \cell +\pard\intbl\qc\fs16 4795 mg \cell +\pard\intbl\qc\fs16 07MAR2014 (63) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1199 \cell -\pard\intbl\qc\fs16 87 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-706-1049 \cell +\pard\intbl\qc\fs16 60 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 493 [unit] \cell -\pard\intbl\qc\fs16 29SEP2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18JUN2013 (400) \cell +\pard\intbl\qc\fs16 3184 mg \cell +\pard\intbl\qc\fs16 25JUN2013 (43) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1393 \cell -\pard\intbl\qc\fs16 84 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-708-1178 \cell +\pard\intbl\qc\fs16 77 / Female / Unknown \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3762 [unit] \cell -\pard\intbl\qc\fs16 20FEB2013 \cell +\pard\intbl\qc\fs16 06APR2014 (300) \cell +\pard\intbl\qc\fs16 1184 mg \cell +\pard\intbl\qc\fs16 06APR2014 (99) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -1500,263 +1500,263 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-707-1037 \cell -\pard\intbl\qc\fs16 72 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-708-1216 \cell +\pard\intbl\qc\fs16 78 / Male / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 1543 [unit] \cell -\pard\intbl\qc\fs16 08JAN2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 29NOV2012 (200) \cell +\pard\intbl\qc\fs16 2563 mg \cell +\pard\intbl\qc\fs16 06DEC2012 (44) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1019 \cell -\pard\intbl\qc\fs16 68 / M / Asian \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1177 [unit] \cell -\pard\intbl\qc\fs16 23JAN2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 21SEP2013 (400) \cell +\pard\intbl\qc\fs16 1890 mg \cell +\pard\intbl\qc\fs16 26SEP2013 (6) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1272 \cell -\pard\intbl\qc\fs16 82 / M / Not reported \cell +\pard\intbl\qc\fs16 01-708-1372 \cell +\pard\intbl\qc\fs16 84 / Male / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 201 [unit] \cell -\pard\intbl\qc\fs16 04APR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 19APR2013 (200) \cell +\pard\intbl\qc\fs16 3733 mg \cell +\pard\intbl\qc\fs16 10MAY2013 (29) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1297 \cell -\pard\intbl\qc\fs16 61 / M / Not reported \cell +\pard\intbl\qc\fs16 01-709-1168 \cell +\pard\intbl\qc\fs16 72 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3732 [unit] \cell -\pard\intbl\qc\fs16 08MAY2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 26SEP2013 (400) \cell +\pard\intbl\qc\fs16 1517 mg \cell +\pard\intbl\qc\fs16 27SEP2013 (57) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1428 \cell -\pard\intbl\qc\fs16 84 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-709-1238 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2365 [unit] \cell -\pard\intbl\qc\fs16 31JAN2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 06AUG2013 (300) \cell +\pard\intbl\qc\fs16 2419 mg \cell +\pard\intbl\qc\fs16 07AUG2013 (85) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1007 \cell -\pard\intbl\qc\fs16 54 / F / Other \cell +\pard\intbl\qc\fs16 01-709-1329 \cell +\pard\intbl\qc\fs16 70 / Male / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3261 [unit] \cell -\pard\intbl\qc\fs16 01SEP2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 25AUG2013 (200) \cell +\pard\intbl\qc\fs16 4597 mg \cell +\pard\intbl\qc\fs16 29AUG2013 (15) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1081 \cell -\pard\intbl\qc\fs16 86 / F / White \cell +\pard\intbl\qc\fs16 01-709-1424 \cell +\pard\intbl\qc\fs16 77 / Male / Other \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 4439 [unit] \cell -\pard\intbl\qc\fs16 10MAY2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 07MAR2013 (50) \cell +\pard\intbl\qc\fs16 3680 mg \cell +\pard\intbl\qc\fs16 08MAR2013 (6) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1102 \cell -\pard\intbl\qc\fs16 71 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-710-1021 \cell +\pard\intbl\qc\fs16 79 / Male / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 250 [unit] \cell -\pard\intbl\qc\fs16 31MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 29OCT2013 (100) \cell +\pard\intbl\qc\fs16 2838 mg \cell +\pard\intbl\qc\fs16 12NOV2013 (47) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1217 \cell -\pard\intbl\qc\fs16 77 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-710-1070 \cell +\pard\intbl\qc\fs16 85 / Female / Unknown \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3360 [unit] \cell -\pard\intbl\qc\fs16 25JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 22JAN2013 (400) \cell +\pard\intbl\qc\fs16 1307 mg \cell +\pard\intbl\qc\fs16 23FEB2013 (169) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1285 \cell -\pard\intbl\qc\fs16 87 / M / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-710-1137 \cell +\pard\intbl\qc\fs16 79 / Female / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3992 [unit] \cell -\pard\intbl\qc\fs16 31MAY2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 13NOV2013 (200) \cell +\pard\intbl\qc\fs16 3437 mg \cell +\pard\intbl\qc\fs16 13NOV2013 (34) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1002 \cell -\pard\intbl\qc\fs16 88 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-710-1142 \cell +\pard\intbl\qc\fs16 76 / Female / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3307 [unit] \cell -\pard\intbl\qc\fs16 18JAN2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 20OCT2012 (50) \cell +\pard\intbl\qc\fs16 836 mg \cell +\pard\intbl\qc\fs16 23OCT2012 (22) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1045 \cell -\pard\intbl\qc\fs16 83 / F / White \cell +\pard\intbl\qc\fs16 01-710-1278 \cell +\pard\intbl\qc\fs16 81 / Male / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2351 [unit] \cell -\pard\intbl\qc\fs16 17AUG2013 \cell +\pard\intbl\qc\fs16 26FEB2013 (50) \cell +\pard\intbl\qc\fs16 2316 mg \cell +\pard\intbl\qc\fs16 03MAR2013 (70) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -1764,65 +1764,65 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1053 \cell -\pard\intbl\qc\fs16 84 / F / White \cell +\pard\intbl\qc\fs16 01-711-1012 \cell +\pard\intbl\qc\fs16 67 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1326 [unit] \cell -\pard\intbl\qc\fs16 15FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 29APR2013 (100) \cell +\pard\intbl\qc\fs16 1241 mg \cell +\pard\intbl\qc\fs16 02MAY2013 (30) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1154 \cell -\pard\intbl\qc\fs16 84 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-711-1433 \cell +\pard\intbl\qc\fs16 84 / Female / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 774 [unit] \cell -\pard\intbl\qc\fs16 09MAY2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 05FEB2013 (50) \cell +\pard\intbl\qc\fs16 3732 mg \cell +\pard\intbl\qc\fs16 06FEB2013 (11) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1166 \cell -\pard\intbl\qc\fs16 81 / F / White \cell +\pard\intbl\qc\fs16 01-713-1141 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2262 [unit] \cell -\pard\intbl\qc\fs16 30MAR2013 \cell +\pard\intbl\qc\fs16 01JUL2013 (300) \cell +\pard\intbl\qc\fs16 2920 mg \cell +\pard\intbl\qc\fs16 06AUG2013 (68) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -1830,197 +1830,197 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1300 \cell -\pard\intbl\qc\fs16 78 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-714-1425 \cell +\pard\intbl\qc\fs16 81 / Male / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 385 [unit] \cell -\pard\intbl\qc\fs16 19FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 19AUG2013 (100) \cell +\pard\intbl\qc\fs16 387 mg \cell +\pard\intbl\qc\fs16 22AUG2013 (8) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1358 \cell -\pard\intbl\qc\fs16 82 / M / Asian \cell +\pard\intbl\qc\fs16 01-715-1319 \cell +\pard\intbl\qc\fs16 65 / Male / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1754 [unit] \cell -\pard\intbl\qc\fs16 12MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 05MAR2013 (400) \cell +\pard\intbl\qc\fs16 2985 mg \cell +\pard\intbl\qc\fs16 18MAR2013 (30) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-711-1143 \cell -\pard\intbl\qc\fs16 76 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-715-1321 \cell +\pard\intbl\qc\fs16 75 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4182 [unit] \cell -\pard\intbl\qc\fs16 01JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 21APR2014 (200) \cell +\pard\intbl\qc\fs16 1665 mg \cell +\pard\intbl\qc\fs16 22APR2014 (71) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-714-1068 \cell -\pard\intbl\qc\fs16 79 / F / Other \cell +\pard\intbl\qc\fs16 01-716-1071 \cell +\pard\intbl\qc\fs16 78 / Female / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 1659 [unit] \cell -\pard\intbl\qc\fs16 16OCT2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01AUG2013 (50) \cell +\pard\intbl\qc\fs16 2079 mg \cell +\pard\intbl\qc\fs16 01AUG2013 (55) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-715-1107 \cell -\pard\intbl\qc\fs16 65 / M / Asian \cell +\pard\intbl\qc\fs16 01-716-1229 \cell +\pard\intbl\qc\fs16 73 / Female / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 1737 [unit] \cell -\pard\intbl\qc\fs16 13MAY2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 31MAR2013 (300) \cell +\pard\intbl\qc\fs16 1653 mg \cell +\pard\intbl\qc\fs16 02APR2013 (42) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1063 \cell -\pard\intbl\qc\fs16 80 / M / Asian \cell +\pard\intbl\qc\fs16 01-716-1373 \cell +\pard\intbl\qc\fs16 74 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4153 [unit] \cell -\pard\intbl\qc\fs16 28AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 27FEB2013 (200) \cell +\pard\intbl\qc\fs16 3027 mg \cell +\pard\intbl\qc\fs16 28FEB2013 (77) \cell +\pard\intbl\qc\fs16 Death \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1151 \cell -\pard\intbl\qc\fs16 83 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-717-1357 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4803 [unit] \cell -\pard\intbl\qc\fs16 07JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 14OCT2013 (200) \cell +\pard\intbl\qc\fs16 772 mg \cell +\pard\intbl\qc\fs16 20OCT2013 (173) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1311 \cell -\pard\intbl\qc\fs16 78 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-718-1101 \cell +\pard\intbl\qc\fs16 82 / Male / Asian \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 626 [unit] \cell -\pard\intbl\qc\fs16 30SEP2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 31JUL2013 (400) \cell +\pard\intbl\qc\fs16 4281 mg \cell +\pard\intbl\qc\fs16 02AUG2013 (167) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1066 \cell -\pard\intbl\qc\fs16 79 / F / Asian \cell +\pard\intbl\qc\fs16 01-718-1328 \cell +\pard\intbl\qc\fs16 86 / Male / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 655 [unit] \cell -\pard\intbl\qc\fs16 30JUL2013 \cell +\pard\intbl\qc\fs16 18APR2013 (300) \cell +\pard\intbl\qc\fs16 2359 mg \cell +\pard\intbl\qc\fs16 01MAY2013 (90) \cell \pard\intbl\qc\fs16 Other \cell \row } @@ -2028,232 +2028,232 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1079 \cell -\pard\intbl\qc\fs16 67 / F / White \cell +\pard\intbl\qc\fs16 01-718-1371 \cell +\pard\intbl\qc\fs16 69 / Female / Unknown \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 102 [unit] \cell -\pard\intbl\qc\fs16 06NOV2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01AUG2013 (50) \cell +\pard\intbl\qc\fs16 2350 mg \cell +\pard\intbl\qc\fs16 08AUG2013 (105) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1250 \cell -\pard\intbl\qc\fs16 82 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-718-1427 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 665 [unit] \cell -\pard\intbl\qc\fs16 08FEB2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 11FEB2013 (400) \cell +\pard\intbl\qc\fs16 3053 mg \cell +\pard\intbl\qc\fs16 18FEB2013 (64) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Placebo \cell \pard\intbl\qc\fs16 01-701-1023 \cell -\pard\intbl\qc\fs16 64 / M / Black or African American \cell +\pard\intbl\qc\fs16 64 / Male / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 795 [unit] \cell -\pard\intbl\qc\fs16 02SEP2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01SEP2012 (50) \cell +\pard\intbl\qc\fs16 3128 mg \cell +\pard\intbl\qc\fs16 02SEP2012 (29) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 01-701-1047 \cell -\pard\intbl\qc\fs16 85 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 85 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 208 [unit] \cell -\pard\intbl\qc\fs16 29MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 09MAR2013 (400) \cell +\pard\intbl\qc\fs16 3659 mg \cell +\pard\intbl\qc\fs16 29MAR2013 (46) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 01-701-1345 \cell -\pard\intbl\qc\fs16 63 / F / Other \cell +\pard\intbl\qc\fs16 63 / Female / Other \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2543 [unit] \cell -\pard\intbl\qc\fs16 18MAR2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18MAR2014 (400) \cell +\pard\intbl\qc\fs16 4098 mg \cell +\pard\intbl\qc\fs16 18MAR2014 (162) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 01-701-1387 \cell -\pard\intbl\qc\fs16 87 / F / Unknown \cell +\pard\intbl\qc\fs16 87 / Female / Unknown \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4173 [unit] \cell -\pard\intbl\qc\fs16 25MAR2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 25MAR2014 (300) \cell +\pard\intbl\qc\fs16 3497 mg \cell +\pard\intbl\qc\fs16 25MAR2014 (14) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 01-703-1096 \cell -\pard\intbl\qc\fs16 81 / F / Black or African American \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1544 [unit] \cell -\pard\intbl\qc\fs16 29MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 16MAR2013 (400) \cell +\pard\intbl\qc\fs16 776 mg \cell +\pard\intbl\qc\fs16 29MAR2013 (64) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 01-703-1175 \cell -\pard\intbl\qc\fs16 75 / M / Multiple \cell +\pard\intbl\qc\fs16 75 / Male / Multiple \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1562 [unit] \cell -\pard\intbl\qc\fs16 31DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 26DEC2013 (100) \cell +\pard\intbl\qc\fs16 3644 mg \cell +\pard\intbl\qc\fs16 31DEC2013 (12) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 01-704-1260 \cell -\pard\intbl\qc\fs16 71 / F / Not reported \cell +\pard\intbl\qc\fs16 71 / Female / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2313 [unit] \cell -\pard\intbl\qc\fs16 18JAN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 04NOV2012 (50) \cell +\pard\intbl\qc\fs16 4449 mg \cell +\pard\intbl\qc\fs16 18JAN2013 (142) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2630 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5616 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6641 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8245 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9493 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10295 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2050 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5036 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6061 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7666 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9136 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10027 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11498 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 01-704-1435 \cell -\pard\intbl\qc\fs16 74 / M / Not reported \cell +\pard\intbl\qc\fs16 74 / Male / Not reported \cell \pard\intbl\qc\fs16 Treatment \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 833 [unit] \cell -\pard\intbl\qc\fs16 12JAN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 09JAN2013 (200) \cell +\pard\intbl\qc\fs16 527 mg \cell +\pard\intbl\qc\fs16 12JAN2013 (57) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \row } { \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2630 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5616 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6641 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8245 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9493 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10295 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2050 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5036 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6061 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7666 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9136 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10027 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11498 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2270,12 +2270,12 @@ { \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2630 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5616 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6641 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8245 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9493 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10295 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2050 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5036 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6061 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7666 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9136 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10027 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11498 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/lsids02/lsids02.rtf b/tests/testthat/_snaps/lsids02/lsids02.rtf old mode 100755 new mode 100644 index 89c577d1..f3bfeb63 --- a/tests/testthat/_snaps/lsids02/lsids02.rtf +++ b/tests/testthat/_snaps/lsids02/lsids02.rtf @@ -6,10 +6,9 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx940 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1521 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4517 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5814 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7022 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7827 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9079 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6127 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7245 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8721 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9616 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10823 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12030 @@ -23,7 +22,6 @@ \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell \row } @@ -32,10 +30,9 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx940 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1521 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4517 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7022 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7827 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9079 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6127 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7245 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8721 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9616 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10823 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12030 @@ -43,11 +40,10 @@ \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell \pard\intbl\qc\fs16 \keepn\trhdr Last Study Visit\super a\nosupersub \cell -\pard\intbl\qc\fs16 \keepn\trhdr Study Day\super b\nosupersub of Discontinuation \cell -\pard\intbl\qc\fs16 \keepn\trhdr Last Treatment Visit\super c\nosupersub \cell -\pard\intbl\qc\fs16 \keepn\trhdr Study Day\super b\nosupersub of Last Study Agent Administered \cell -\pard\intbl\qc\fs16 \keepn\trhdr Total Dose (unit)\super d\nosupersub \cell -\pard\intbl\qc\fs16 \keepn\trhdr Date of Discontinuation \cell +\pard\intbl\qc\fs16 \keepn\trhdr Last Treatment Visit\super b\nosupersub \cell +\pard\intbl\qc\fs16 \keepn\trhdr Date of Last Study Agent Administered (Study Day\super c\nosupersub ) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Cumulative Dose (unit) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Date of Discontinuation (Study Day\super c\nosupersub ) \cell \pard\intbl\qc\fs16 \keepn\trhdr Primary Reason for Discontinuation \cell \pard\intbl\qc\fs16 \keepn\trhdr Was Blind Broken? \cell \row @@ -58,23 +54,21 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1146 \cell -\pard\intbl\qc\fs16 75 / F / Unknown \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 42 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 682 [unit] \cell -\pard\intbl\qc\fs16 30JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 16SEP2012 (300) \cell +\pard\intbl\qc\fs16 3012 mg \cell +\pard\intbl\qc\fs16 17SEP2012 (11) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -84,23 +78,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1181 \cell -\pard\intbl\qc\fs16 79 / F / Not reported \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 8 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 3375 [unit] \cell -\pard\intbl\qc\fs16 12DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 23JAN2013 (200) \cell +\pard\intbl\qc\fs16 1296 mg \cell +\pard\intbl\qc\fs16 23JAN2013 (55) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -110,22 +102,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1360 \cell -\pard\intbl\qc\fs16 67 / M / Multiple \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 15 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 3744 [unit] \cell -\pard\intbl\qc\fs16 14AUG2013 \cell +\pard\intbl\qc\fs16 12JAN2013 (200) \cell +\pard\intbl\qc\fs16 4810 mg \cell +\pard\intbl\qc\fs16 14JAN2013 (61) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -136,23 +126,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1444 \cell -\pard\intbl\qc\fs16 63 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 67 / Male / Other \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 40 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3217 [unit] \cell -\pard\intbl\qc\fs16 13FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 14JUN2013 (300) \cell +\pard\intbl\qc\fs16 2807 mg \cell +\pard\intbl\qc\fs16 14JUN2013 (83) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -162,23 +150,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1076 \cell -\pard\intbl\qc\fs16 69 / M / White \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 51 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 61 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4866 [unit] \cell -\pard\intbl\qc\fs16 24DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 26JAN2013 (200) \cell +\pard\intbl\qc\fs16 4710 mg \cell +\pard\intbl\qc\fs16 07FEB2013 (34) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -188,23 +174,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1335 \cell -\pard\intbl\qc\fs16 67 / F / Not reported \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 84 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 69 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4144 [unit] \cell -\pard\intbl\qc\fs16 24MAY2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 30APR2013 (100) \cell +\pard\intbl\qc\fs16 2242 mg \cell +\pard\intbl\qc\fs16 30APR2013 (43) \cell +\pard\intbl\qc\fs16 Death \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -214,23 +198,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1403 \cell -\pard\intbl\qc\fs16 67 / M / Multiple \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 81 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 8 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4799 [unit] \cell -\pard\intbl\qc\fs16 19DEC2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 13JUN2013 (100) \cell +\pard\intbl\qc\fs16 4461 mg \cell +\pard\intbl\qc\fs16 13JUN2013 (114) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -240,23 +222,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1017 \cell -\pard\intbl\qc\fs16 77 / M / Asian \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 84 / Male / Other \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 50 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 1561 [unit] \cell -\pard\intbl\qc\fs16 24NOV2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 11DEC2013 (100) \cell +\pard\intbl\qc\fs16 2020 mg \cell +\pard\intbl\qc\fs16 12DEC2013 (57) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -266,23 +246,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1065 \cell -\pard\intbl\qc\fs16 75 / M / Multiple \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 62 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4487 [unit] \cell -\pard\intbl\qc\fs16 24DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 29JUN2013 (300) \cell +\pard\intbl\qc\fs16 4525 mg \cell +\pard\intbl\qc\fs16 22JUL2013 (37) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -292,22 +270,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1093 \cell -\pard\intbl\qc\fs16 79 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-704-1009 \cell +\pard\intbl\qc\fs16 83 / Male / Unknown \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 98 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1035 [unit] \cell -\pard\intbl\qc\fs16 20JUN2013 \cell +\pard\intbl\qc\fs16 25SEP2013 (50) \cell +\pard\intbl\qc\fs16 768 mg \cell +\pard\intbl\qc\fs16 02OCT2013 (37) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -318,23 +294,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1281 \cell -\pard\intbl\qc\fs16 73 / F / Not reported \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 81 / Female / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 110 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4016 [unit] \cell -\pard\intbl\qc\fs16 17MAR2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 24OCT2013 (50) \cell +\pard\intbl\qc\fs16 1715 mg \cell +\pard\intbl\qc\fs16 29NOV2013 (64) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -344,23 +318,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1303 \cell -\pard\intbl\qc\fs16 72 / M / Unknown \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 77 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 169 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4880 [unit] \cell -\pard\intbl\qc\fs16 02JUN2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 07JUL2013 (100) \cell +\pard\intbl\qc\fs16 2240 mg \cell +\pard\intbl\qc\fs16 08JUL2013 (167) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -370,23 +342,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1310 \cell -\pard\intbl\qc\fs16 74 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 71 / Female / Black or African American \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 83 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2580 [unit] \cell -\pard\intbl\qc\fs16 23JAN2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01FEB2014 (400) \cell +\pard\intbl\qc\fs16 4108 mg \cell +\pard\intbl\qc\fs16 03FEB2014 (64) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -396,23 +366,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1382 \cell -\pard\intbl\qc\fs16 82 / M / Multiple \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 68 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 1 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 868 [unit] \cell -\pard\intbl\qc\fs16 13MAY2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 05AUG2013 (400) \cell +\pard\intbl\qc\fs16 1570 mg \cell +\pard\intbl\qc\fs16 08AUG2013 (32) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -422,23 +390,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1213 \cell -\pard\intbl\qc\fs16 76 / F / Unknown \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 18 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4105 [unit] \cell -\pard\intbl\qc\fs16 26FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 04JUL2014 (400) \cell +\pard\intbl\qc\fs16 3769 mg \cell +\pard\intbl\qc\fs16 06AUG2014 (106) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -448,23 +414,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1216 \cell -\pard\intbl\qc\fs16 78 / M / Asian \cell +\pard\intbl\qc\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 56 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 44 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 4138 [unit] \cell -\pard\intbl\qc\fs16 06DEC2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18DEC2013 (400) \cell +\pard\intbl\qc\fs16 4398 mg \cell +\pard\intbl\qc\fs16 11MAY2014 (166) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -474,22 +438,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1236 \cell -\pard\intbl\qc\fs16 86 / F / White \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 87 / Male / Black or African American \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 6 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3262 [unit] \cell -\pard\intbl\qc\fs16 26SEP2013 \cell +\pard\intbl\qc\fs16 28SEP2013 (300) \cell +\pard\intbl\qc\fs16 4284 mg \cell +\pard\intbl\qc\fs16 29SEP2013 (14) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -500,23 +462,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1347 \cell -\pard\intbl\qc\fs16 61 / F / White \cell +\pard\intbl\qc\fs16 01-705-1393 \cell +\pard\intbl\qc\fs16 84 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 60 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2169 [unit] \cell -\pard\intbl\qc\fs16 18JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01FEB2013 (100) \cell +\pard\intbl\qc\fs16 1908 mg \cell +\pard\intbl\qc\fs16 20FEB2013 (167) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -526,22 +486,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1372 \cell -\pard\intbl\qc\fs16 84 / M / Not reported \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 72 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 29 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1322 [unit] \cell -\pard\intbl\qc\fs16 10MAY2013 \cell +\pard\intbl\qc\fs16 24DEC2013 (200) \cell +\pard\intbl\qc\fs16 596 mg \cell +\pard\intbl\qc\fs16 08JAN2014 (20) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -552,23 +510,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1329 \cell -\pard\intbl\qc\fs16 70 / M / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-708-1019 \cell +\pard\intbl\qc\fs16 68 / Male / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 15 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 756 [unit] \cell -\pard\intbl\qc\fs16 29AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01JAN2014 (100) \cell +\pard\intbl\qc\fs16 2506 mg \cell +\pard\intbl\qc\fs16 23JAN2014 (35) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -578,23 +534,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1137 \cell -\pard\intbl\qc\fs16 79 / F / Multiple \cell +\pard\intbl\qc\fs16 01-708-1032 \cell +\pard\intbl\qc\fs16 62 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 34 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4505 [unit] \cell -\pard\intbl\qc\fs16 13NOV2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01MAR2013 (300) \cell +\pard\intbl\qc\fs16 2856 mg \cell +\pard\intbl\qc\fs16 09MAR2013 (29) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -604,23 +558,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1142 \cell -\pard\intbl\qc\fs16 76 / F / Not reported \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 82 / Male / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 22 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1884 [unit] \cell -\pard\intbl\qc\fs16 23OCT2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 22MAR2013 (200) \cell +\pard\intbl\qc\fs16 4143 mg \cell +\pard\intbl\qc\fs16 04APR2013 (58) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -630,23 +582,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1278 \cell -\pard\intbl\qc\fs16 81 / M / Asian \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 61 / Male / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 70 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1435 [unit] \cell -\pard\intbl\qc\fs16 03MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 03MAY2013 (200) \cell +\pard\intbl\qc\fs16 3599 mg \cell +\pard\intbl\qc\fs16 08MAY2013 (104) \cell +\pard\intbl\qc\fs16 Death \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -656,23 +606,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-711-1433 \cell -\pard\intbl\qc\fs16 84 / F / Asian \cell +\pard\intbl\qc\fs16 01-708-1428 \cell +\pard\intbl\qc\fs16 84 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 11 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2045 [unit] \cell -\pard\intbl\qc\fs16 06FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 14DEC2013 (200) \cell +\pard\intbl\qc\fs16 2605 mg \cell +\pard\intbl\qc\fs16 31JAN2014 (84) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -682,23 +630,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-713-1141 \cell -\pard\intbl\qc\fs16 79 / M / White \cell +\pard\intbl\qc\fs16 01-709-1081 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 68 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2384 [unit] \cell -\pard\intbl\qc\fs16 06AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 27APR2014 (100) \cell +\pard\intbl\qc\fs16 418 mg \cell +\pard\intbl\qc\fs16 10MAY2014 (113) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -708,23 +654,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-714-1425 \cell -\pard\intbl\qc\fs16 81 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-709-1102 \cell +\pard\intbl\qc\fs16 71 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 8 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 3686 [unit] \cell -\pard\intbl\qc\fs16 22AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 27MAR2013 (400) \cell +\pard\intbl\qc\fs16 1302 mg \cell +\pard\intbl\qc\fs16 31MAR2013 (76) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -734,23 +678,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-715-1319 \cell -\pard\intbl\qc\fs16 65 / M / Multiple \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 77 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 30 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3797 [unit] \cell -\pard\intbl\qc\fs16 18MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 11JUN2013 (400) \cell +\pard\intbl\qc\fs16 198 mg \cell +\pard\intbl\qc\fs16 25JUN2013 (114) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -760,23 +702,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-715-1321 \cell -\pard\intbl\qc\fs16 75 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-709-1285 \cell +\pard\intbl\qc\fs16 87 / Male / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 71 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1625 [unit] \cell -\pard\intbl\qc\fs16 22APR2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 23MAY2013 (300) \cell +\pard\intbl\qc\fs16 345 mg \cell +\pard\intbl\qc\fs16 31MAY2013 (69) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -786,23 +726,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1189 \cell -\pard\intbl\qc\fs16 81 / M / Asian \cell +\pard\intbl\qc\fs16 01-710-1002 \cell +\pard\intbl\qc\fs16 88 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 146 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1369 [unit] \cell -\pard\intbl\qc\fs16 03MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18JAN2014 (300) \cell +\pard\intbl\qc\fs16 191 mg \cell +\pard\intbl\qc\fs16 18JAN2014 (5) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -812,22 +750,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1229 \cell -\pard\intbl\qc\fs16 73 / F / Asian \cell +\pard\intbl\qc\fs16 01-710-1045 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 42 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 3984 [unit] \cell -\pard\intbl\qc\fs16 02APR2013 \cell +\pard\intbl\qc\fs16 13AUG2013 (300) \cell +\pard\intbl\qc\fs16 1185 mg \cell +\pard\intbl\qc\fs16 17AUG2013 (76) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -838,23 +774,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-717-1357 \cell -\pard\intbl\qc\fs16 77 / M / White \cell +\pard\intbl\qc\fs16 01-710-1053 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 173 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3353 [unit] \cell -\pard\intbl\qc\fs16 20OCT2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 10FEB2013 (200) \cell +\pard\intbl\qc\fs16 2349 mg \cell +\pard\intbl\qc\fs16 15FEB2013 (52) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -864,22 +798,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1101 \cell -\pard\intbl\qc\fs16 82 / M / Asian \cell +\pard\intbl\qc\fs16 01-710-1154 \cell +\pard\intbl\qc\fs16 84 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 167 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 4406 [unit] \cell -\pard\intbl\qc\fs16 02AUG2013 \cell +\pard\intbl\qc\fs16 27APR2014 (50) \cell +\pard\intbl\qc\fs16 1166 mg \cell +\pard\intbl\qc\fs16 09MAY2014 (42) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -890,23 +822,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1328 \cell -\pard\intbl\qc\fs16 86 / M / Not reported \cell +\pard\intbl\qc\fs16 01-710-1166 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 90 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3352 [unit] \cell -\pard\intbl\qc\fs16 01MAY2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 19MAR2013 (50) \cell +\pard\intbl\qc\fs16 3800 mg \cell +\pard\intbl\qc\fs16 30MAR2013 (121) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -916,23 +846,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1371 \cell -\pard\intbl\qc\fs16 69 / F / Unknown \cell +\pard\intbl\qc\fs16 01-710-1270 \cell +\pard\intbl\qc\fs16 83 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 105 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3454 [unit] \cell -\pard\intbl\qc\fs16 08AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01MAR2014 (50) \cell +\pard\intbl\qc\fs16 2034 mg \cell +\pard\intbl\qc\fs16 01MAR2014 (18) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -942,23 +870,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 01-701-1111 \cell -\pard\intbl\qc\fs16 81 / F / White \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1300 \cell +\pard\intbl\qc\fs16 78 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 11 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2572 [unit] \cell -\pard\intbl\qc\fs16 17SEP2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 15FEB2013 (200) \cell +\pard\intbl\qc\fs16 1557 mg \cell +\pard\intbl\qc\fs16 19FEB2013 (67) \cell +\pard\intbl\qc\fs16 Death \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -968,23 +894,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1115 \cell -\pard\intbl\qc\fs16 84 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-710-1358 \cell +\pard\intbl\qc\fs16 82 / Male / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 55 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3252 [unit] \cell -\pard\intbl\qc\fs16 23JAN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 09FEB2013 (200) \cell +\pard\intbl\qc\fs16 3352 mg \cell +\pard\intbl\qc\fs16 12MAR2013 (177) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -994,23 +918,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1211 \cell -\pard\intbl\qc\fs16 76 / F / Other \cell +\pard\intbl\qc\fs16 01-710-1385 \cell +\pard\intbl\qc\fs16 77 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 61 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4245 [unit] \cell -\pard\intbl\qc\fs16 14JAN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18FEB2013 (100) \cell +\pard\intbl\qc\fs16 2612 mg \cell +\pard\intbl\qc\fs16 18FEB2013 (113) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1020,23 +942,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1294 \cell -\pard\intbl\qc\fs16 67 / M / Other \cell +\pard\intbl\qc\fs16 01-711-1143 \cell +\pard\intbl\qc\fs16 76 / Female / Black or African American \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 83 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2017 [unit] \cell -\pard\intbl\qc\fs16 14JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 30MAY2013 (100) \cell +\pard\intbl\qc\fs16 2234 mg \cell +\pard\intbl\qc\fs16 01JUN2013 (60) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1046,23 +966,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1341 \cell -\pard\intbl\qc\fs16 51 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-713-1448 \cell +\pard\intbl\qc\fs16 71 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 34 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1354 [unit] \cell -\pard\intbl\qc\fs16 07FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 16MAY2014 (400) \cell +\pard\intbl\qc\fs16 3784 mg \cell +\pard\intbl\qc\fs16 17MAY2014 (119) \cell +\pard\intbl\qc\fs16 Death \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1072,23 +990,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1429 \cell -\pard\intbl\qc\fs16 84 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-714-1068 \cell +\pard\intbl\qc\fs16 79 / Female / Other \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 43 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2949 [unit] \cell -\pard\intbl\qc\fs16 30APR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 08OCT2013 (100) \cell +\pard\intbl\qc\fs16 998 mg \cell +\pard\intbl\qc\fs16 16OCT2013 (70) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1098,23 +1014,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1119 \cell -\pard\intbl\qc\fs16 81 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-715-1107 \cell +\pard\intbl\qc\fs16 65 / Male / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 114 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 2288 [unit] \cell -\pard\intbl\qc\fs16 13JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 07MAY2013 (100) \cell +\pard\intbl\qc\fs16 2442 mg \cell +\pard\intbl\qc\fs16 13MAY2013 (77) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1124,23 +1038,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1182 \cell -\pard\intbl\qc\fs16 84 / M / Other \cell +\pard\intbl\qc\fs16 01-716-1063 \cell +\pard\intbl\qc\fs16 80 / Male / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 57 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 2075 [unit] \cell -\pard\intbl\qc\fs16 12DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 25AUG2013 (50) \cell +\pard\intbl\qc\fs16 4962 mg \cell +\pard\intbl\qc\fs16 28AUG2013 (112) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1150,23 +1062,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1197 \cell -\pard\intbl\qc\fs16 76 / F / Other \cell +\pard\intbl\qc\fs16 01-716-1094 \cell +\pard\intbl\qc\fs16 82 / Male / Black or African American \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 37 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1716 [unit] \cell -\pard\intbl\qc\fs16 22JUL2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 24JAN2013 (50) \cell +\pard\intbl\qc\fs16 2857 mg \cell +\pard\intbl\qc\fs16 26JAN2013 (39) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1176,23 +1086,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1009 \cell -\pard\intbl\qc\fs16 83 / M / Unknown \cell +\pard\intbl\qc\fs16 01-716-1151 \cell +\pard\intbl\qc\fs16 83 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 37 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 2204 [unit] \cell -\pard\intbl\qc\fs16 02OCT2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 11MAY2013 (50) \cell +\pard\intbl\qc\fs16 1976 mg \cell +\pard\intbl\qc\fs16 07JUN2013 (127) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1202,23 +1110,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1025 \cell -\pard\intbl\qc\fs16 81 / F / Asian \cell +\pard\intbl\qc\fs16 01-716-1311 \cell +\pard\intbl\qc\fs16 78 / Male / Black or African American \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 64 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 958 [unit] \cell -\pard\intbl\qc\fs16 29NOV2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 21SEP2014 (300) \cell +\pard\intbl\qc\fs16 3451 mg \cell +\pard\intbl\qc\fs16 30SEP2014 (140) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1228,23 +1134,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1114 \cell -\pard\intbl\qc\fs16 77 / M / Multiple \cell +\pard\intbl\qc\fs16 01-718-1066 \cell +\pard\intbl\qc\fs16 79 / Female / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 167 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 967 [unit] \cell -\pard\intbl\qc\fs16 08JUL2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 16JUL2013 (100) \cell +\pard\intbl\qc\fs16 3281 mg \cell +\pard\intbl\qc\fs16 30JUL2013 (24) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1254,23 +1158,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1120 \cell -\pard\intbl\qc\fs16 71 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-718-1079 \cell +\pard\intbl\qc\fs16 67 / Female / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 64 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4345 [unit] \cell -\pard\intbl\qc\fs16 03FEB2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 31OCT2012 (300) \cell +\pard\intbl\qc\fs16 3021 mg \cell +\pard\intbl\qc\fs16 06NOV2012 (49) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1280,23 +1182,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1325 \cell -\pard\intbl\qc\fs16 81 / M / White \cell +\pard\intbl\qc\fs16 01-718-1250 \cell +\pard\intbl\qc\fs16 82 / Female / Black or African American \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 106 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4663 [unit] \cell -\pard\intbl\qc\fs16 06AUG2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 31JAN2014 (400) \cell +\pard\intbl\qc\fs16 1993 mg \cell +\pard\intbl\qc\fs16 08FEB2014 (141) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1306,23 +1206,45 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1146 \cell +\pard\intbl\qc\fs16 75 / Female / Unknown \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 26JUN2013 (100) \cell +\pard\intbl\qc\fs16 607 mg \cell +\pard\intbl\qc\fs16 30JUN2013 (42) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1199 \cell -\pard\intbl\qc\fs16 87 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-701-1180 \cell +\pard\intbl\qc\fs16 56 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 14 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 493 [unit] \cell -\pard\intbl\qc\fs16 29SEP2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18MAR2013 (300) \cell +\pard\intbl\qc\fs16 853 mg \cell +\pard\intbl\qc\fs16 23MAR2013 (40) \cell +\pard\intbl\qc\fs16 Death \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1332,23 +1254,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1393 \cell -\pard\intbl\qc\fs16 84 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 79 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 167 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3762 [unit] \cell -\pard\intbl\qc\fs16 20FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 09DEC2013 (100) \cell +\pard\intbl\qc\fs16 4890 mg \cell +\pard\intbl\qc\fs16 12DEC2013 (8) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1358,22 +1278,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1019 \cell -\pard\intbl\qc\fs16 68 / M / Asian \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 67 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 35 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1177 [unit] \cell -\pard\intbl\qc\fs16 23JAN2014 \cell +\pard\intbl\qc\fs16 05AUG2013 (100) \cell +\pard\intbl\qc\fs16 3098 mg \cell +\pard\intbl\qc\fs16 14AUG2013 (15) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -1384,23 +1302,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1032 \cell -\pard\intbl\qc\fs16 62 / M / Multiple \cell +\pard\intbl\qc\fs16 01-701-1444 \cell +\pard\intbl\qc\fs16 63 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 29 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3770 [unit] \cell -\pard\intbl\qc\fs16 09MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 12FEB2013 (100) \cell +\pard\intbl\qc\fs16 1790 mg \cell +\pard\intbl\qc\fs16 13FEB2013 (40) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1410,23 +1326,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1272 \cell -\pard\intbl\qc\fs16 82 / M / Not reported \cell +\pard\intbl\qc\fs16 01-703-1076 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 58 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 201 [unit] \cell -\pard\intbl\qc\fs16 04APR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 24DEC2013 (50) \cell +\pard\intbl\qc\fs16 2763 mg \cell +\pard\intbl\qc\fs16 24DEC2013 (61) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1436,23 +1350,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1297 \cell -\pard\intbl\qc\fs16 61 / M / Not reported \cell +\pard\intbl\qc\fs16 01-703-1295 \cell +\pard\intbl\qc\fs16 88 / Female / Other \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 104 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3732 [unit] \cell -\pard\intbl\qc\fs16 08MAY2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 19APR2014 (100) \cell +\pard\intbl\qc\fs16 2629 mg \cell +\pard\intbl\qc\fs16 19MAY2014 (180) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1462,23 +1374,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1081 \cell -\pard\intbl\qc\fs16 86 / F / White \cell +\pard\intbl\qc\fs16 01-703-1335 \cell +\pard\intbl\qc\fs16 67 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 113 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 4439 [unit] \cell -\pard\intbl\qc\fs16 10MAY2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 07MAY2014 (300) \cell +\pard\intbl\qc\fs16 1521 mg \cell +\pard\intbl\qc\fs16 24MAY2014 (69) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1488,23 +1398,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1102 \cell -\pard\intbl\qc\fs16 71 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-703-1403 \cell +\pard\intbl\qc\fs16 67 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 76 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 250 [unit] \cell -\pard\intbl\qc\fs16 31MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 13DEC2012 (50) \cell +\pard\intbl\qc\fs16 2825 mg \cell +\pard\intbl\qc\fs16 19DEC2012 (8) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1514,23 +1422,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1217 \cell -\pard\intbl\qc\fs16 77 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-704-1017 \cell +\pard\intbl\qc\fs16 77 / Male / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 114 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3360 [unit] \cell -\pard\intbl\qc\fs16 25JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18NOV2013 (50) \cell +\pard\intbl\qc\fs16 856 mg \cell +\pard\intbl\qc\fs16 24NOV2013 (50) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1540,22 +1446,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1285 \cell -\pard\intbl\qc\fs16 87 / M / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-704-1065 \cell +\pard\intbl\qc\fs16 75 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 69 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3992 [unit] \cell -\pard\intbl\qc\fs16 31MAY2013 \cell +\pard\intbl\qc\fs16 22DEC2013 (100) \cell +\pard\intbl\qc\fs16 3493 mg \cell +\pard\intbl\qc\fs16 24DEC2013 (62) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -1566,23 +1470,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1002 \cell -\pard\intbl\qc\fs16 88 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-704-1093 \cell +\pard\intbl\qc\fs16 79 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 5 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3307 [unit] \cell -\pard\intbl\qc\fs16 18JAN2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 17JUN2013 (300) \cell +\pard\intbl\qc\fs16 1177 mg \cell +\pard\intbl\qc\fs16 20JUN2013 (98) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1592,23 +1494,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1053 \cell -\pard\intbl\qc\fs16 84 / F / White \cell +\pard\intbl\qc\fs16 01-704-1241 \cell +\pard\intbl\qc\fs16 86 / Male / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 52 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1326 [unit] \cell -\pard\intbl\qc\fs16 15FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 09OCT2013 (50) \cell +\pard\intbl\qc\fs16 367 mg \cell +\pard\intbl\qc\fs16 31OCT2013 (68) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1618,23 +1518,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1154 \cell -\pard\intbl\qc\fs16 84 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-705-1281 \cell +\pard\intbl\qc\fs16 73 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 42 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 774 [unit] \cell -\pard\intbl\qc\fs16 09MAY2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 27FEB2014 (50) \cell +\pard\intbl\qc\fs16 4050 mg \cell +\pard\intbl\qc\fs16 17MAR2014 (110) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1644,23 +1542,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1166 \cell -\pard\intbl\qc\fs16 81 / F / White \cell +\pard\intbl\qc\fs16 01-705-1303 \cell +\pard\intbl\qc\fs16 72 / Male / Unknown \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 121 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2262 [unit] \cell -\pard\intbl\qc\fs16 30MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 30DEC2013 (400) \cell +\pard\intbl\qc\fs16 3807 mg \cell +\pard\intbl\qc\fs16 02JUN2014 (169) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1670,22 +1566,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1270 \cell -\pard\intbl\qc\fs16 83 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-705-1310 \cell +\pard\intbl\qc\fs16 74 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 18 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1047 [unit] \cell -\pard\intbl\qc\fs16 01MAR2014 \cell +\pard\intbl\qc\fs16 23JAN2014 (200) \cell +\pard\intbl\qc\fs16 3630 mg \cell +\pard\intbl\qc\fs16 23JAN2014 (83) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -1696,23 +1590,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1358 \cell -\pard\intbl\qc\fs16 82 / M / Asian \cell +\pard\intbl\qc\fs16 01-705-1377 \cell +\pard\intbl\qc\fs16 63 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 177 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1754 [unit] \cell -\pard\intbl\qc\fs16 12MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 25JAN2014 (400) \cell +\pard\intbl\qc\fs16 4795 mg \cell +\pard\intbl\qc\fs16 07MAR2014 (63) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1722,23 +1614,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1385 \cell -\pard\intbl\qc\fs16 77 / M / Multiple \cell +\pard\intbl\qc\fs16 01-705-1382 \cell +\pard\intbl\qc\fs16 82 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 113 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 4978 [unit] \cell -\pard\intbl\qc\fs16 18FEB2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 (400) \cell +\pard\intbl\qc\fs16 4324 mg \cell +\pard\intbl\qc\fs16 13MAY2013 (1) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1748,23 +1638,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-711-1143 \cell -\pard\intbl\qc\fs16 76 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-706-1049 \cell +\pard\intbl\qc\fs16 60 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 60 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4182 [unit] \cell -\pard\intbl\qc\fs16 01JUN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18JUN2013 (400) \cell +\pard\intbl\qc\fs16 3184 mg \cell +\pard\intbl\qc\fs16 25JUN2013 (43) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1774,23 +1662,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-713-1448 \cell -\pard\intbl\qc\fs16 71 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-708-1178 \cell +\pard\intbl\qc\fs16 77 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 119 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 774 [unit] \cell -\pard\intbl\qc\fs16 17MAY2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 06APR2014 (300) \cell +\pard\intbl\qc\fs16 1184 mg \cell +\pard\intbl\qc\fs16 06APR2014 (99) \cell +\pard\intbl\qc\fs16 Death \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1800,23 +1686,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-714-1068 \cell -\pard\intbl\qc\fs16 79 / F / Other \cell +\pard\intbl\qc\fs16 01-708-1213 \cell +\pard\intbl\qc\fs16 76 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 70 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 1659 [unit] \cell -\pard\intbl\qc\fs16 16OCT2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 22FEB2013 (50) \cell +\pard\intbl\qc\fs16 215 mg \cell +\pard\intbl\qc\fs16 26FEB2013 (18) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1826,23 +1710,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1063 \cell -\pard\intbl\qc\fs16 80 / M / Asian \cell +\pard\intbl\qc\fs16 01-708-1216 \cell +\pard\intbl\qc\fs16 78 / Male / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 112 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4153 [unit] \cell -\pard\intbl\qc\fs16 28AUG2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 29NOV2012 (200) \cell +\pard\intbl\qc\fs16 2563 mg \cell +\pard\intbl\qc\fs16 06DEC2012 (44) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1852,23 +1734,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1094 \cell -\pard\intbl\qc\fs16 82 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 39 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2465 [unit] \cell -\pard\intbl\qc\fs16 26JAN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 21SEP2013 (400) \cell +\pard\intbl\qc\fs16 1890 mg \cell +\pard\intbl\qc\fs16 26SEP2013 (6) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1878,23 +1758,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1311 \cell -\pard\intbl\qc\fs16 78 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-708-1347 \cell +\pard\intbl\qc\fs16 61 / Female / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 140 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 626 [unit] \cell -\pard\intbl\qc\fs16 30SEP2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 18JUN2013 (200) \cell +\pard\intbl\qc\fs16 2588 mg \cell +\pard\intbl\qc\fs16 18JUN2013 (60) \cell +\pard\intbl\qc\fs16 Pregnancy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1904,23 +1782,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1079 \cell -\pard\intbl\qc\fs16 67 / F / White \cell +\pard\intbl\qc\fs16 01-708-1372 \cell +\pard\intbl\qc\fs16 84 / Male / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 49 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 102 [unit] \cell -\pard\intbl\qc\fs16 06NOV2012 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 19APR2013 (200) \cell +\pard\intbl\qc\fs16 3733 mg \cell +\pard\intbl\qc\fs16 10MAY2013 (29) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1930,23 +1806,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1250 \cell -\pard\intbl\qc\fs16 82 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-709-1238 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 141 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 665 [unit] \cell -\pard\intbl\qc\fs16 08FEB2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 06AUG2013 (300) \cell +\pard\intbl\qc\fs16 2419 mg \cell +\pard\intbl\qc\fs16 07AUG2013 (85) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -1956,22 +1830,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Placebo \cell -\pard\intbl\qc\fs16 01-701-1023 \cell -\pard\intbl\qc\fs16 64 / M / Black or African American \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1329 \cell +\pard\intbl\qc\fs16 70 / Male / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 29 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 795 [unit] \cell -\pard\intbl\qc\fs16 02SEP2012 \cell +\pard\intbl\qc\fs16 25AUG2013 (200) \cell +\pard\intbl\qc\fs16 4597 mg \cell +\pard\intbl\qc\fs16 29AUG2013 (15) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -1982,23 +1854,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1047 \cell -\pard\intbl\qc\fs16 85 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-709-1424 \cell +\pard\intbl\qc\fs16 77 / Male / Other \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 46 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 208 [unit] \cell -\pard\intbl\qc\fs16 29MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 07MAR2013 (50) \cell +\pard\intbl\qc\fs16 3680 mg \cell +\pard\intbl\qc\fs16 08MAR2013 (6) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -2008,22 +1878,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1345 \cell -\pard\intbl\qc\fs16 63 / F / Other \cell +\pard\intbl\qc\fs16 01-710-1070 \cell +\pard\intbl\qc\fs16 85 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 162 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2543 [unit] \cell -\pard\intbl\qc\fs16 18MAR2014 \cell +\pard\intbl\qc\fs16 22JAN2013 (400) \cell +\pard\intbl\qc\fs16 1307 mg \cell +\pard\intbl\qc\fs16 23FEB2013 (169) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -2034,23 +1902,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1387 \cell -\pard\intbl\qc\fs16 87 / F / Unknown \cell +\pard\intbl\qc\fs16 01-710-1137 \cell +\pard\intbl\qc\fs16 79 / Female / Multiple \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 14 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4173 [unit] \cell -\pard\intbl\qc\fs16 25MAR2014 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 13NOV2013 (200) \cell +\pard\intbl\qc\fs16 3437 mg \cell +\pard\intbl\qc\fs16 13NOV2013 (34) \cell +\pard\intbl\qc\fs16 Adverse Event \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -2060,23 +1926,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1096 \cell -\pard\intbl\qc\fs16 81 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-710-1142 \cell +\pard\intbl\qc\fs16 76 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 64 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1544 [unit] \cell -\pard\intbl\qc\fs16 29MAR2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 20OCT2012 (50) \cell +\pard\intbl\qc\fs16 836 mg \cell +\pard\intbl\qc\fs16 23OCT2012 (22) \cell +\pard\intbl\qc\fs16 Protocol Violation \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -2086,22 +1950,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1175 \cell -\pard\intbl\qc\fs16 75 / M / Multiple \cell +\pard\intbl\qc\fs16 01-710-1278 \cell +\pard\intbl\qc\fs16 81 / Male / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 12 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1562 [unit] \cell -\pard\intbl\qc\fs16 31DEC2013 \cell +\pard\intbl\qc\fs16 26FEB2013 (50) \cell +\pard\intbl\qc\fs16 2316 mg \cell +\pard\intbl\qc\fs16 03MAR2013 (70) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -2112,23 +1974,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1233 \cell -\pard\intbl\qc\fs16 87 / F / Not reported \cell +\pard\intbl\qc\fs16 01-711-1012 \cell +\pard\intbl\qc\fs16 67 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 116 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 4514 [unit] \cell -\pard\intbl\qc\fs16 14JUL2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 29APR2013 (100) \cell +\pard\intbl\qc\fs16 1241 mg \cell +\pard\intbl\qc\fs16 02MAY2013 (30) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -2138,23 +1998,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1260 \cell -\pard\intbl\qc\fs16 71 / F / Not reported \cell +\pard\intbl\qc\fs16 01-711-1433 \cell +\pard\intbl\qc\fs16 84 / Female / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 142 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2313 [unit] \cell -\pard\intbl\qc\fs16 18JAN2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 05FEB2013 (50) \cell +\pard\intbl\qc\fs16 3732 mg \cell +\pard\intbl\qc\fs16 06FEB2013 (11) \cell +\pard\intbl\qc\fs16 Death \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -2164,23 +2022,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1059 \cell -\pard\intbl\qc\fs16 66 / F / Other \cell +\pard\intbl\qc\fs16 01-713-1141 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 123 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 2531 [unit] \cell -\pard\intbl\qc\fs16 05DEC2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 01JUL2013 (300) \cell +\pard\intbl\qc\fs16 2920 mg \cell +\pard\intbl\qc\fs16 06AUG2013 (68) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -2190,22 +2046,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1378 \cell -\pard\intbl\qc\fs16 67 / M / Other \cell +\pard\intbl\qc\fs16 01-714-1425 \cell +\pard\intbl\qc\fs16 81 / Male / Black or African American \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 148 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2773 [unit] \cell -\pard\intbl\qc\fs16 28JAN2014 \cell +\pard\intbl\qc\fs16 19AUG2013 (100) \cell +\pard\intbl\qc\fs16 387 mg \cell +\pard\intbl\qc\fs16 22AUG2013 (8) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -2216,22 +2070,20 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1259 \cell -\pard\intbl\qc\fs16 82 / M / Other \cell +\pard\intbl\qc\fs16 01-715-1319 \cell +\pard\intbl\qc\fs16 65 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 139 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4418 [unit] \cell -\pard\intbl\qc\fs16 13JUN2013 \cell +\pard\intbl\qc\fs16 05MAR2013 (400) \cell +\pard\intbl\qc\fs16 2985 mg \cell +\pard\intbl\qc\fs16 18MAR2013 (30) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -2242,23 +2094,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1314 \cell -\pard\intbl\qc\fs16 78 / F / Asian \cell +\pard\intbl\qc\fs16 01-715-1321 \cell +\pard\intbl\qc\fs16 75 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 32 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4148 [unit] \cell -\pard\intbl\qc\fs16 25MAY2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 21APR2014 (200) \cell +\pard\intbl\qc\fs16 1665 mg \cell +\pard\intbl\qc\fs16 22APR2014 (71) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -2268,23 +2118,21 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1315 \cell -\pard\intbl\qc\fs16 83 / F / Unknown \cell +\pard\intbl\qc\fs16 01-716-1189 \cell +\pard\intbl\qc\fs16 81 / Male / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 140 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2660 [unit] \cell -\pard\intbl\qc\fs16 16JUL2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 27FEB2013 (100) \cell +\pard\intbl\qc\fs16 3556 mg \cell +\pard\intbl\qc\fs16 03MAR2013 (146) \cell +\pard\intbl\qc\fs16 Withdrawal by Subject \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -2294,22 +2142,68 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-715-1155 \cell -\pard\intbl\qc\fs16 59 / F / Multiple \cell +\pard\intbl\qc\fs16 01-716-1229 \cell +\pard\intbl\qc\fs16 73 / Female / Asian \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 135 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 655 [unit] \cell -\pard\intbl\qc\fs16 26APR2014 \cell +\pard\intbl\qc\fs16 31MAR2013 (300) \cell +\pard\intbl\qc\fs16 1653 mg \cell +\pard\intbl\qc\fs16 02APR2013 (42) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1357 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 14OCT2013 (200) \cell +\pard\intbl\qc\fs16 772 mg \cell +\pard\intbl\qc\fs16 20OCT2013 (173) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1101 \cell +\pard\intbl\qc\fs16 82 / Male / Asian \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 31JUL2013 (400) \cell +\pard\intbl\qc\fs16 4281 mg \cell +\pard\intbl\qc\fs16 02AUG2013 (167) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row @@ -2320,49 +2214,237 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1328 \cell +\pard\intbl\qc\fs16 86 / Male / Not reported \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 18APR2013 (300) \cell +\pard\intbl\qc\fs16 2359 mg \cell +\pard\intbl\qc\fs16 01MAY2013 (90) \cell +\pard\intbl\qc\fs16 Death \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-717-1201 \cell -\pard\intbl\qc\fs16 85 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-718-1371 \cell +\pard\intbl\qc\fs16 69 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 65 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2506 [unit] \cell -\pard\intbl\qc\fs16 21FEB2014 \cell +\pard\intbl\qc\fs16 01AUG2013 (50) \cell +\pard\intbl\qc\fs16 2350 mg \cell +\pard\intbl\qc\fs16 08AUG2013 (105) \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-701-1023 \cell +\pard\intbl\qc\fs16 64 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 01SEP2012 (50) \cell +\pard\intbl\qc\fs16 3128 mg \cell +\pard\intbl\qc\fs16 02SEP2012 (29) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1047 \cell +\pard\intbl\qc\fs16 85 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 09MAR2013 (400) \cell +\pard\intbl\qc\fs16 3659 mg \cell +\pard\intbl\qc\fs16 29MAR2013 (46) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1345 \cell +\pard\intbl\qc\fs16 63 / Female / Other \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 18MAR2014 (400) \cell +\pard\intbl\qc\fs16 4098 mg \cell +\pard\intbl\qc\fs16 18MAR2014 (162) \cell \pard\intbl\qc\fs16 Other \cell \pard\intbl\qc\fs16 Yes \cell \row } +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1387 \cell +\pard\intbl\qc\fs16 87 / Female / Unknown \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 25MAR2014 (300) \cell +\pard\intbl\qc\fs16 3497 mg \cell +\pard\intbl\qc\fs16 25MAR2014 (14) \cell +\pard\intbl\qc\fs16 Adverse Event \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1096 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 16MAR2013 (400) \cell +\pard\intbl\qc\fs16 776 mg \cell +\pard\intbl\qc\fs16 29MAR2013 (64) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1175 \cell +\pard\intbl\qc\fs16 75 / Male / Multiple \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 26DEC2013 (100) \cell +\pard\intbl\qc\fs16 3644 mg \cell +\pard\intbl\qc\fs16 31DEC2013 (12) \cell +\pard\intbl\qc\fs16 Pregnancy \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1010 \cell +\pard\intbl\qc\fs16 80 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Last Study Visit \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 08JUL2014 (100) \cell +\pard\intbl\qc\fs16 2455 mg \cell +\pard\intbl\qc\fs16 09JUL2014 (139) \cell +\pard\intbl\qc\fs16 Lack of Efficacy \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx940 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1521 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4517 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5814 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7022 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7827 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9079 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6127 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7245 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8721 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9616 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10823 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12030 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1172 \cell -\pard\intbl\qc\fs16 74 / M / Multiple \cell +\pard\intbl\qc\fs16 01-704-1233 \cell +\pard\intbl\qc\fs16 87 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Study Visit \cell -\pard\intbl\qc\fs16 70 \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4945 [unit] \cell -\pard\intbl\qc\fs16 29NOV2013 \cell -\pard\intbl\qc\fs16 Other \cell +\pard\intbl\qc\fs16 04APR2013 (50) \cell +\pard\intbl\qc\fs16 399 mg \cell +\pard\intbl\qc\fs16 14JUL2013 (116) \cell +\pard\intbl\qc\fs16 Lost to Follow-up \cell \pard\intbl\qc\fs16 Yes \cell \row } @@ -2372,10 +2454,9 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx940 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1521 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4517 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7022 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7827 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9079 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6127 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7245 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8721 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9616 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10823 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12030 @@ -2389,7 +2470,6 @@ \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } @@ -2398,10 +2478,9 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx940 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1521 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4517 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7022 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7827 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9079 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6127 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7245 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8721 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9616 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10823 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12030 @@ -2415,7 +2494,6 @@ \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell -\pard\intbl\qc \cell \row } \par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} diff --git a/tests/testthat/_snaps/lsids03/lsids03.rtf b/tests/testthat/_snaps/lsids03/lsids03.rtf old mode 100755 new mode 100644 index fbcc5a66..7c0374db --- a/tests/testthat/_snaps/lsids03/lsids03.rtf +++ b/tests/testthat/_snaps/lsids03/lsids03.rtf @@ -3,15 +3,15 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1828 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4813 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6284 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7175 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8423 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8958 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9849 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10963 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx956 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1548 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4598 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5418 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6465 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7967 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8877 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9788 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10926 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIDS03:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -27,22 +27,22 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4813 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6284 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7175 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8423 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8958 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9849 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10963 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx956 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1548 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4598 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5418 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6465 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7967 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8877 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9788 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10926 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell \pard\intbl\qc\fs16 \keepn\trhdr Last Visit\super a\nosupersub \cell -\pard\intbl\qc\fs16 \keepn\trhdr Study Day\super b\nosupersub of Unblinding \cell -\pard\intbl\qc\fs16 \keepn\trhdr Study Day\super b\nosupersub of Last Study Agent Administered \cell -\pard\intbl\qc\fs16 \keepn\trhdr Total Dose (unit)\super c\nosupersub \cell +\pard\intbl\qc\fs16 \keepn\trhdr Date of Unblinding (Study Day\super b\nosupersub ) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Date of Last Study Agent Administered (Study Day\super b\nosupersub ) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Cumulative Dose (unit) \cell \pard\intbl\qc\fs16 \keepn\trhdr Reason for Unblinding \cell \pard\intbl\qc\fs16 \keepn\trhdr Was Study Agent Discontinued? \cell \pard\intbl\qc\fs16 \keepn\trhdr Was Study Participation Discontinued Prematurely? \cell @@ -51,70 +51,70 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 71 / M / Asian \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3661 [unit] \cell +\pard\intbl\qc\fs16 19MAR2014 (1) \cell +\pard\intbl\qc\fs16 31MAR2014 (400) \cell +\pard\intbl\qc\fs16 2039 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 77 / F / White \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 445 [unit] \cell +\pard\intbl\qc\fs16 08SEP2012 (1) \cell +\pard\intbl\qc\fs16 16SEP2012 (300) \cell +\pard\intbl\qc\fs16 3012 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1146 \cell -\pard\intbl\qc\fs16 75 / F / Unknown \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 682 [unit] \cell +\pard\intbl\qc\fs16 01DEC2012 (1) \cell +\pard\intbl\qc\fs16 23JAN2013 (200) \cell +\pard\intbl\qc\fs16 1296 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -123,94 +123,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1148 \cell -\pard\intbl\qc\fs16 57 / M / Not reported \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3301 [unit] \cell +\pard\intbl\qc\fs16 16FEB2013 (1) \cell +\pard\intbl\qc\fs16 24MAR2013 (50) \cell +\pard\intbl\qc\fs16 4786 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1181 \cell -\pard\intbl\qc\fs16 79 / F / Not reported \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 3375 [unit] \cell +\pard\intbl\qc\fs16 23JUL2012 (1) \cell +\pard\intbl\qc\fs16 20JAN2013 (50) \cell +\pard\intbl\qc\fs16 2534 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1239 \cell -\pard\intbl\qc\fs16 56 / M / White \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 723 [unit] \cell +\pard\intbl\qc\fs16 16NOV2012 (1) \cell +\pard\intbl\qc\fs16 12JAN2013 (200) \cell +\pard\intbl\qc\fs16 4810 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1275 \cell -\pard\intbl\qc\fs16 61 / M / White \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 68 / Male / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 643 [unit] \cell +\pard\intbl\qc\fs16 23MAY2014 (1) \cell +\pard\intbl\qc\fs16 20NOV2014 (300) \cell +\pard\intbl\qc\fs16 4286 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -219,22 +219,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1287 \cell -\pard\intbl\qc\fs16 56 / F / Multiple \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 79 / Male / Asian \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 2233 [unit] \cell +\pard\intbl\qc\fs16 03OCT2012 (1) \cell +\pard\intbl\qc\fs16 02APR2013 (300) \cell +\pard\intbl\qc\fs16 2079 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -243,46 +243,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1302 \cell -\pard\intbl\qc\fs16 61 / M / Asian \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 51 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1285 [unit] \cell +\pard\intbl\qc\fs16 06JAN2013 (1) \cell +\pard\intbl\qc\fs16 26JAN2013 (200) \cell +\pard\intbl\qc\fs16 4710 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1360 \cell -\pard\intbl\qc\fs16 67 / M / Multiple \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 84 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 3744 [unit] \cell +\pard\intbl\qc\fs16 20MAR2013 (1) \cell +\pard\intbl\qc\fs16 30APR2013 (100) \cell +\pard\intbl\qc\fs16 2242 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -291,46 +291,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1383 \cell -\pard\intbl\qc\fs16 72 / F / Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1592 [unit] \cell -\pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1444 \cell -\pard\intbl\qc\fs16 63 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 84 / Male / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3217 [unit] \cell +\pard\intbl\qc\fs16 18OCT2013 (1) \cell +\pard\intbl\qc\fs16 11DEC2013 (100) \cell +\pard\intbl\qc\fs16 2020 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -339,22 +315,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1076 \cell -\pard\intbl\qc\fs16 69 / M / White \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4866 [unit] \cell +\pard\intbl\qc\fs16 17JUN2013 (1) \cell +\pard\intbl\qc\fs16 29JUN2013 (300) \cell +\pard\intbl\qc\fs16 4525 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -363,22 +339,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1258 \cell -\pard\intbl\qc\fs16 78 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-703-1279 \cell +\pard\intbl\qc\fs16 72 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4920 [unit] \cell +\pard\intbl\qc\fs16 14MAY2013 (1) \cell +\pard\intbl\qc\fs16 03JUN2013 (50) \cell +\pard\intbl\qc\fs16 2467 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 No \cell @@ -387,70 +363,70 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1335 \cell -\pard\intbl\qc\fs16 67 / F / Not reported \cell +\pard\intbl\qc\fs16 01-703-1379 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4144 [unit] \cell +\pard\intbl\qc\fs16 23SEP2013 (1) \cell +\pard\intbl\qc\fs16 21MAR2014 (400) \cell +\pard\intbl\qc\fs16 3903 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1403 \cell -\pard\intbl\qc\fs16 67 / M / Multiple \cell +\pard\intbl\qc\fs16 01-704-1009 \cell +\pard\intbl\qc\fs16 83 / Male / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4799 [unit] \cell +\pard\intbl\qc\fs16 28AUG2013 (1) \cell +\pard\intbl\qc\fs16 25SEP2013 (50) \cell +\pard\intbl\qc\fs16 768 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1008 \cell -\pard\intbl\qc\fs16 76 / F / White \cell +\pard\intbl\qc\fs16 01-704-1135 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1671 [unit] \cell +\pard\intbl\qc\fs16 01NOV2013 (1) \cell +\pard\intbl\qc\fs16 16MAY2014 (400) \cell +\pard\intbl\qc\fs16 3153 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -459,46 +435,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1017 \cell -\pard\intbl\qc\fs16 77 / M / Asian \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 81 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 1561 [unit] \cell +\pard\intbl\qc\fs16 20NOV2012 (1) \cell +\pard\intbl\qc\fs16 27MAY2013 (300) \cell +\pard\intbl\qc\fs16 4235 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1065 \cell -\pard\intbl\qc\fs16 75 / M / Multiple \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 68 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4487 [unit] \cell +\pard\intbl\qc\fs16 09JUL2013 (1) \cell +\pard\intbl\qc\fs16 05AUG2013 (400) \cell +\pard\intbl\qc\fs16 1570 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -507,46 +483,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1074 \cell -\pard\intbl\qc\fs16 80 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 56 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1741 [unit] \cell +\pard\intbl\qc\fs16 28NOV2013 (1) \cell +\pard\intbl\qc\fs16 18DEC2013 (400) \cell +\pard\intbl\qc\fs16 4398 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1093 \cell -\pard\intbl\qc\fs16 79 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 87 / Male / Black or African American \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1035 [unit] \cell +\pard\intbl\qc\fs16 17SEP2013 (1) \cell +\pard\intbl\qc\fs16 28SEP2013 (300) \cell +\pard\intbl\qc\fs16 4284 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -555,46 +531,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1266 \cell -\pard\intbl\qc\fs16 82 / M / Multiple \cell +\pard\intbl\qc\fs16 01-705-1431 \cell +\pard\intbl\qc\fs16 68 / Female / Black or African American \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3347 [unit] \cell +\pard\intbl\qc\fs16 24JUN2013 (1) \cell +\pard\intbl\qc\fs16 19DEC2013 (200) \cell +\pard\intbl\qc\fs16 2282 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1280 \cell -\pard\intbl\qc\fs16 56 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-706-1384 \cell +\pard\intbl\qc\fs16 74 / Female / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3394 [unit] \cell +\pard\intbl\qc\fs16 16SEP2012 (1) \cell +\pard\intbl\qc\fs16 24SEP2012 (300) \cell +\pard\intbl\qc\fs16 4975 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -603,22 +579,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1281 \cell -\pard\intbl\qc\fs16 73 / F / Not reported \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 72 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4016 [unit] \cell +\pard\intbl\qc\fs16 21DEC2013 (1) \cell +\pard\intbl\qc\fs16 24DEC2013 (200) \cell +\pard\intbl\qc\fs16 596 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -627,22 +603,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1303 \cell -\pard\intbl\qc\fs16 72 / M / Unknown \cell +\pard\intbl\qc\fs16 01-708-1019 \cell +\pard\intbl\qc\fs16 68 / Male / Asian \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4880 [unit] \cell +\pard\intbl\qc\fs16 21DEC2013 (1) \cell +\pard\intbl\qc\fs16 01JAN2014 (100) \cell +\pard\intbl\qc\fs16 2506 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -651,142 +627,142 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1310 \cell -\pard\intbl\qc\fs16 74 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-708-1032 \cell +\pard\intbl\qc\fs16 62 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2580 [unit] \cell +\pard\intbl\qc\fs16 10FEB2013 (1) \cell +\pard\intbl\qc\fs16 01MAR2013 (300) \cell +\pard\intbl\qc\fs16 2856 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1382 \cell -\pard\intbl\qc\fs16 82 / M / Multiple \cell +\pard\intbl\qc\fs16 01-708-1084 \cell +\pard\intbl\qc\fs16 73 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 868 [unit] \cell +\pard\intbl\qc\fs16 10MAY2013 (1) \cell +\pard\intbl\qc\fs16 11NOV2013 (200) \cell +\pard\intbl\qc\fs16 3029 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1213 \cell -\pard\intbl\qc\fs16 76 / F / Unknown \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 61 / Male / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4105 [unit] \cell +\pard\intbl\qc\fs16 26JAN2013 (1) \cell +\pard\intbl\qc\fs16 03MAY2013 (200) \cell +\pard\intbl\qc\fs16 3599 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1216 \cell -\pard\intbl\qc\fs16 78 / M / Asian \cell +\pard\intbl\qc\fs16 01-708-1348 \cell +\pard\intbl\qc\fs16 79 / Female / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 4138 [unit] \cell +\pard\intbl\qc\fs16 06AUG2013 (1) \cell +\pard\intbl\qc\fs16 13FEB2014 (300) \cell +\pard\intbl\qc\fs16 3976 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1236 \cell -\pard\intbl\qc\fs16 86 / F / White \cell +\pard\intbl\qc\fs16 01-708-1353 \cell +\pard\intbl\qc\fs16 87 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3262 [unit] \cell +\pard\intbl\qc\fs16 05JUL2013 (1) \cell +\pard\intbl\qc\fs16 28AUG2013 (50) \cell +\pard\intbl\qc\fs16 3931 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1336 \cell -\pard\intbl\qc\fs16 73 / M / Other \cell +\pard\intbl\qc\fs16 01-709-1020 \cell +\pard\intbl\qc\fs16 72 / Female / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4927 [unit] \cell +\pard\intbl\qc\fs16 02DEC2012 (1) \cell +\pard\intbl\qc\fs16 01JUN2013 (400) \cell +\pard\intbl\qc\fs16 3924 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -795,46 +771,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1347 \cell -\pard\intbl\qc\fs16 61 / F / White \cell +\pard\intbl\qc\fs16 01-709-1081 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2169 [unit] \cell +\pard\intbl\qc\fs16 19JAN2014 (1) \cell +\pard\intbl\qc\fs16 27APR2014 (100) \cell +\pard\intbl\qc\fs16 418 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1372 \cell -\pard\intbl\qc\fs16 84 / M / Not reported \cell +\pard\intbl\qc\fs16 01-709-1102 \cell +\pard\intbl\qc\fs16 71 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1322 [unit] \cell +\pard\intbl\qc\fs16 16JAN2013 (1) \cell +\pard\intbl\qc\fs16 27MAR2013 (400) \cell +\pard\intbl\qc\fs16 1302 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -843,70 +819,70 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1099 \cell -\pard\intbl\qc\fs16 79 / F / Multiple \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 77 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 2619 [unit] \cell +\pard\intbl\qc\fs16 05MAR2013 (1) \cell +\pard\intbl\qc\fs16 11JUN2013 (400) \cell +\pard\intbl\qc\fs16 198 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1168 \cell -\pard\intbl\qc\fs16 72 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-709-1285 \cell +\pard\intbl\qc\fs16 87 / Male / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 572 [unit] \cell +\pard\intbl\qc\fs16 25MAR2013 (1) \cell +\pard\intbl\qc\fs16 23MAY2013 (300) \cell +\pard\intbl\qc\fs16 345 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1309 \cell -\pard\intbl\qc\fs16 65 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-709-1326 \cell +\pard\intbl\qc\fs16 75 / Female / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3825 [unit] \cell +\pard\intbl\qc\fs16 06APR2013 (1) \cell +\pard\intbl\qc\fs16 02OCT2013 (400) \cell +\pard\intbl\qc\fs16 1273 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -915,22 +891,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1329 \cell -\pard\intbl\qc\fs16 70 / M / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-710-1002 \cell +\pard\intbl\qc\fs16 88 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 756 [unit] \cell +\pard\intbl\qc\fs16 15JAN2014 (1) \cell +\pard\intbl\qc\fs16 18JAN2014 (300) \cell +\pard\intbl\qc\fs16 191 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -939,70 +915,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1006 \cell -\pard\intbl\qc\fs16 77 / M / Asian \cell +\pard\intbl\qc\fs16 01-710-1053 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3309 [unit] \cell +\pard\intbl\qc\fs16 27DEC2012 (1) \cell +\pard\intbl\qc\fs16 10FEB2013 (200) \cell +\pard\intbl\qc\fs16 2349 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1021 \cell -\pard\intbl\qc\fs16 79 / M / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-710-1166 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1225 [unit] \cell +\pard\intbl\qc\fs16 01DEC2012 (1) \cell +\pard\intbl\qc\fs16 19MAR2013 (50) \cell +\pard\intbl\qc\fs16 3800 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 Yes \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1270 \cell +\pard\intbl\qc\fs16 83 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Last Treatment Visit \cell +\pard\intbl\qc\fs16 13FEB2014 (1) \cell +\pard\intbl\qc\fs16 01MAR2014 (50) \cell +\pard\intbl\qc\fs16 2034 mg \cell +\pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1137 \cell -\pard\intbl\qc\fs16 79 / F / Multiple \cell +\pard\intbl\qc\fs16 01-710-1300 \cell +\pard\intbl\qc\fs16 78 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4505 [unit] \cell +\pard\intbl\qc\fs16 16DEC2012 (1) \cell +\pard\intbl\qc\fs16 15FEB2013 (200) \cell +\pard\intbl\qc\fs16 1557 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1011,22 +1011,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1142 \cell -\pard\intbl\qc\fs16 76 / F / Not reported \cell +\pard\intbl\qc\fs16 01-710-1358 \cell +\pard\intbl\qc\fs16 82 / Male / Asian \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1884 [unit] \cell +\pard\intbl\qc\fs16 18SEP2012 (1) \cell +\pard\intbl\qc\fs16 09FEB2013 (200) \cell +\pard\intbl\qc\fs16 3352 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1035,46 +1035,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1187 \cell -\pard\intbl\qc\fs16 78 / F / Unknown \cell +\pard\intbl\qc\fs16 01-710-1385 \cell +\pard\intbl\qc\fs16 77 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 510 [unit] \cell +\pard\intbl\qc\fs16 30OCT2012 (1) \cell +\pard\intbl\qc\fs16 18FEB2013 (100) \cell +\pard\intbl\qc\fs16 2612 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1278 \cell -\pard\intbl\qc\fs16 81 / M / Asian \cell +\pard\intbl\qc\fs16 01-711-1143 \cell +\pard\intbl\qc\fs16 76 / Female / Black or African American \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1435 [unit] \cell +\pard\intbl\qc\fs16 04APR2013 (1) \cell +\pard\intbl\qc\fs16 30MAY2013 (100) \cell +\pard\intbl\qc\fs16 2234 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1083,22 +1083,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1354 \cell -\pard\intbl\qc\fs16 73 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-713-1043 \cell +\pard\intbl\qc\fs16 78 / Female / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 3500 [unit] \cell +\pard\intbl\qc\fs16 16SEP2013 (1) \cell +\pard\intbl\qc\fs16 24MAR2014 (100) \cell +\pard\intbl\qc\fs16 3339 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -1107,22 +1107,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1408 \cell -\pard\intbl\qc\fs16 80 / M / Multiple \cell +\pard\intbl\qc\fs16 01-713-1073 \cell +\pard\intbl\qc\fs16 74 / Female / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 298 [unit] \cell +\pard\intbl\qc\fs16 31MAR2014 (1) \cell +\pard\intbl\qc\fs16 05OCT2014 (400) \cell +\pard\intbl\qc\fs16 3926 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -1131,46 +1131,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-711-1433 \cell -\pard\intbl\qc\fs16 84 / F / Asian \cell +\pard\intbl\qc\fs16 01-713-1448 \cell +\pard\intbl\qc\fs16 71 / Female / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2045 [unit] \cell +\pard\intbl\qc\fs16 20JAN2014 (1) \cell +\pard\intbl\qc\fs16 16MAY2014 (400) \cell +\pard\intbl\qc\fs16 3784 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-713-1141 \cell -\pard\intbl\qc\fs16 79 / M / White \cell +\pard\intbl\qc\fs16 01-714-1068 \cell +\pard\intbl\qc\fs16 79 / Female / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2384 [unit] \cell +\pard\intbl\qc\fs16 09AUG2013 (1) \cell +\pard\intbl\qc\fs16 08OCT2013 (100) \cell +\pard\intbl\qc\fs16 998 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1179,22 +1179,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-714-1288 \cell -\pard\intbl\qc\fs16 77 / M / Multiple \cell +\pard\intbl\qc\fs16 01-715-1085 \cell +\pard\intbl\qc\fs16 77 / Female / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3820 [unit] \cell +\pard\intbl\qc\fs16 17FEB2013 (1) \cell +\pard\intbl\qc\fs16 18AUG2013 (400) \cell +\pard\intbl\qc\fs16 167 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -1203,70 +1203,70 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-714-1425 \cell -\pard\intbl\qc\fs16 81 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-715-1405 \cell +\pard\intbl\qc\fs16 69 / Male / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 3686 [unit] \cell +\pard\intbl\qc\fs16 07JUL2013 (1) \cell +\pard\intbl\qc\fs16 07JUL2013 (300) \cell +\pard\intbl\qc\fs16 1377 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-715-1319 \cell -\pard\intbl\qc\fs16 65 / M / Multiple \cell +\pard\intbl\qc\fs16 01-716-1094 \cell +\pard\intbl\qc\fs16 82 / Male / Black or African American \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3797 [unit] \cell +\pard\intbl\qc\fs16 20DEC2012 (1) \cell +\pard\intbl\qc\fs16 24JAN2013 (50) \cell +\pard\intbl\qc\fs16 2857 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-715-1321 \cell -\pard\intbl\qc\fs16 75 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-716-1151 \cell +\pard\intbl\qc\fs16 83 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1625 [unit] \cell +\pard\intbl\qc\fs16 02FEB2013 (1) \cell +\pard\intbl\qc\fs16 11MAY2013 (50) \cell +\pard\intbl\qc\fs16 1976 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1275,22 +1275,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1030 \cell -\pard\intbl\qc\fs16 83 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-716-1157 \cell +\pard\intbl\qc\fs16 85 / Male / Asian \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3929 [unit] \cell +\pard\intbl\qc\fs16 03OCT2013 (1) \cell +\pard\intbl\qc\fs16 04APR2014 (100) \cell +\pard\intbl\qc\fs16 2060 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -1299,94 +1299,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1071 \cell -\pard\intbl\qc\fs16 78 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-716-1167 \cell +\pard\intbl\qc\fs16 68 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4590 [unit] \cell +\pard\intbl\qc\fs16 09OCT2012 (1) \cell +\pard\intbl\qc\fs16 12APR2013 (100) \cell +\pard\intbl\qc\fs16 3854 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1189 \cell -\pard\intbl\qc\fs16 81 / M / Asian \cell +\pard\intbl\qc\fs16 01-716-1298 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1369 [unit] \cell +\pard\intbl\qc\fs16 09APR2013 (1) \cell +\pard\intbl\qc\fs16 28JUN2013 (100) \cell +\pard\intbl\qc\fs16 3249 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1229 \cell -\pard\intbl\qc\fs16 73 / F / Asian \cell +\pard\intbl\qc\fs16 01-717-1004 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 3984 [unit] \cell +\pard\intbl\qc\fs16 15JAN2014 (1) \cell +\pard\intbl\qc\fs16 16JUL2014 (400) \cell +\pard\intbl\qc\fs16 1290 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1364 \cell -\pard\intbl\qc\fs16 84 / F / Unknown \cell +\pard\intbl\qc\fs16 01-717-1446 \cell +\pard\intbl\qc\fs16 75 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4319 [unit] \cell +\pard\intbl\qc\fs16 02SEP2013 (1) \cell +\pard\intbl\qc\fs16 03MAR2014 (200) \cell +\pard\intbl\qc\fs16 1489 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -1395,46 +1395,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1373 \cell -\pard\intbl\qc\fs16 74 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-718-1066 \cell +\pard\intbl\qc\fs16 79 / Female / Asian \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3481 [unit] \cell +\pard\intbl\qc\fs16 08JUL2013 (1) \cell +\pard\intbl\qc\fs16 16JUL2013 (100) \cell +\pard\intbl\qc\fs16 3281 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1418 \cell -\pard\intbl\qc\fs16 80 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-718-1170 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2820 [unit] \cell +\pard\intbl\qc\fs16 17SEP2013 (1) \cell +\pard\intbl\qc\fs16 12OCT2013 (100) \cell +\pard\intbl\qc\fs16 4043 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -1443,22 +1443,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-716-1447 \cell -\pard\intbl\qc\fs16 72 / F / Unknown \cell +\pard\intbl\qc\fs16 01-718-1254 \cell +\pard\intbl\qc\fs16 78 / Male / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 4744 [unit] \cell +\pard\intbl\qc\fs16 11JUL2013 (1) \cell +\pard\intbl\qc\fs16 09JAN2014 (200) \cell +\pard\intbl\qc\fs16 555 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -1467,22 +1467,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-717-1109 \cell -\pard\intbl\qc\fs16 84 / M / Asian \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1028 \cell +\pard\intbl\qc\fs16 71 / Male / Asian \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1523 [unit] \cell +\pard\intbl\qc\fs16 20JUL2013 (1) \cell +\pard\intbl\qc\fs16 14JAN2014 (300) \cell +\pard\intbl\qc\fs16 2483 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -1491,70 +1491,70 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-717-1357 \cell -\pard\intbl\qc\fs16 77 / M / White \cell +\pard\intbl\qc\fs16 01-701-1034 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3353 [unit] \cell +\pard\intbl\qc\fs16 02JUL2014 (1) \cell +\pard\intbl\qc\fs16 30DEC2014 (50) \cell +\pard\intbl\qc\fs16 4173 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1101 \cell -\pard\intbl\qc\fs16 82 / M / Asian \cell +\pard\intbl\qc\fs16 01-701-1133 \cell +\pard\intbl\qc\fs16 81 / Female / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 4406 [unit] \cell +\pard\intbl\qc\fs16 29OCT2012 (1) \cell +\pard\intbl\qc\fs16 28APR2013 (100) \cell +\pard\intbl\qc\fs16 1194 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1328 \cell -\pard\intbl\qc\fs16 86 / M / Not reported \cell +\pard\intbl\qc\fs16 01-701-1146 \cell +\pard\intbl\qc\fs16 75 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3352 [unit] \cell +\pard\intbl\qc\fs16 21MAY2013 (1) \cell +\pard\intbl\qc\fs16 26JUN2013 (100) \cell +\pard\intbl\qc\fs16 607 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1563,22 +1563,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-718-1371 \cell -\pard\intbl\qc\fs16 69 / F / Unknown \cell +\pard\intbl\qc\fs16 01-701-1180 \cell +\pard\intbl\qc\fs16 56 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3454 [unit] \cell +\pard\intbl\qc\fs16 13FEB2013 (1) \cell +\pard\intbl\qc\fs16 18MAR2013 (300) \cell +\pard\intbl\qc\fs16 853 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1587,94 +1587,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell -\pard\intbl\qc\fs16 01-701-1033 \cell -\pard\intbl\qc\fs16 74 / M / Multiple \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 79 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2167 [unit] \cell +\pard\intbl\qc\fs16 06DEC2013 (1) \cell +\pard\intbl\qc\fs16 09DEC2013 (100) \cell +\pard\intbl\qc\fs16 4890 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1111 \cell -\pard\intbl\qc\fs16 81 / F / White \cell +\pard\intbl\qc\fs16 01-701-1239 \cell +\pard\intbl\qc\fs16 56 / Male / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 2572 [unit] \cell +\pard\intbl\qc\fs16 12JAN2014 (1) \cell +\pard\intbl\qc\fs16 10JUL2014 (400) \cell +\pard\intbl\qc\fs16 493 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1115 \cell -\pard\intbl\qc\fs16 84 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-701-1275 \cell +\pard\intbl\qc\fs16 61 / Male / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3252 [unit] \cell +\pard\intbl\qc\fs16 08FEB2014 (1) \cell +\pard\intbl\qc\fs16 31MAY2014 (400) \cell +\pard\intbl\qc\fs16 119 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1188 \cell -\pard\intbl\qc\fs16 71 / M / White \cell +\pard\intbl\qc\fs16 01-701-1302 \cell +\pard\intbl\qc\fs16 61 / Male / Asian \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 933 [unit] \cell +\pard\intbl\qc\fs16 30AUG2013 (1) \cell +\pard\intbl\qc\fs16 05NOV2013 (300) \cell +\pard\intbl\qc\fs16 4945 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 No \cell @@ -1683,46 +1683,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1192 \cell -\pard\intbl\qc\fs16 80 / F / Not reported \cell +\pard\intbl\qc\fs16 01-701-1444 \cell +\pard\intbl\qc\fs16 63 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 238 [unit] \cell +\pard\intbl\qc\fs16 06JAN2013 (1) \cell +\pard\intbl\qc\fs16 12FEB2013 (100) \cell +\pard\intbl\qc\fs16 1790 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1211 \cell -\pard\intbl\qc\fs16 76 / F / Other \cell +\pard\intbl\qc\fs16 01-703-1295 \cell +\pard\intbl\qc\fs16 88 / Female / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4245 [unit] \cell +\pard\intbl\qc\fs16 22NOV2013 (1) \cell +\pard\intbl\qc\fs16 19APR2014 (100) \cell +\pard\intbl\qc\fs16 2629 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1731,46 +1731,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1294 \cell -\pard\intbl\qc\fs16 67 / M / Other \cell +\pard\intbl\qc\fs16 01-703-1403 \cell +\pard\intbl\qc\fs16 67 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 2017 [unit] \cell +\pard\intbl\qc\fs16 13DEC2012 (1) \cell +\pard\intbl\qc\fs16 13DEC2012 (50) \cell +\pard\intbl\qc\fs16 2825 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1317 \cell -\pard\intbl\qc\fs16 68 / M / Unknown \cell +\pard\intbl\qc\fs16 01-703-1439 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4352 [unit] \cell +\pard\intbl\qc\fs16 13MAR2014 (1) \cell +\pard\intbl\qc\fs16 11SEP2014 (400) \cell +\pard\intbl\qc\fs16 2274 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -1779,70 +1779,70 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1324 \cell -\pard\intbl\qc\fs16 79 / M / Asian \cell +\pard\intbl\qc\fs16 01-704-1065 \cell +\pard\intbl\qc\fs16 75 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 4543 [unit] \cell +\pard\intbl\qc\fs16 25OCT2013 (1) \cell +\pard\intbl\qc\fs16 22DEC2013 (100) \cell +\pard\intbl\qc\fs16 3493 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1341 \cell -\pard\intbl\qc\fs16 51 / M / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-704-1093 \cell +\pard\intbl\qc\fs16 79 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 1354 [unit] \cell +\pard\intbl\qc\fs16 16MAR2013 (1) \cell +\pard\intbl\qc\fs16 17JUN2013 (300) \cell +\pard\intbl\qc\fs16 1177 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1429 \cell -\pard\intbl\qc\fs16 84 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-704-1241 \cell +\pard\intbl\qc\fs16 86 / Male / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 2949 [unit] \cell +\pard\intbl\qc\fs16 26AUG2013 (1) \cell +\pard\intbl\qc\fs16 09OCT2013 (50) \cell +\pard\intbl\qc\fs16 367 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1851,46 +1851,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1442 \cell -\pard\intbl\qc\fs16 57 / F / Asian \cell +\pard\intbl\qc\fs16 01-704-1266 \cell +\pard\intbl\qc\fs16 82 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 1596 [unit] \cell +\pard\intbl\qc\fs16 14OCT2013 (1) \cell +\pard\intbl\qc\fs16 06DEC2013 (100) \cell +\pard\intbl\qc\fs16 4354 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-702-1082 \cell -\pard\intbl\qc\fs16 84 / F / Asian \cell +\pard\intbl\qc\fs16 01-705-1280 \cell +\pard\intbl\qc\fs16 56 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1244 [unit] \cell +\pard\intbl\qc\fs16 18JAN2014 (1) \cell +\pard\intbl\qc\fs16 25JUL2014 (300) \cell +\pard\intbl\qc\fs16 4128 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -1899,22 +1899,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1119 \cell -\pard\intbl\qc\fs16 81 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-705-1281 \cell +\pard\intbl\qc\fs16 73 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 2288 [unit] \cell +\pard\intbl\qc\fs16 29NOV2013 (1) \cell +\pard\intbl\qc\fs16 27FEB2014 (50) \cell +\pard\intbl\qc\fs16 4050 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1923,22 +1923,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1182 \cell -\pard\intbl\qc\fs16 84 / M / Other \cell +\pard\intbl\qc\fs16 01-705-1303 \cell +\pard\intbl\qc\fs16 72 / Male / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 2075 [unit] \cell +\pard\intbl\qc\fs16 17DEC2013 (1) \cell +\pard\intbl\qc\fs16 30DEC2013 (400) \cell +\pard\intbl\qc\fs16 3807 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1947,22 +1947,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1197 \cell -\pard\intbl\qc\fs16 76 / F / Other \cell +\pard\intbl\qc\fs16 01-705-1377 \cell +\pard\intbl\qc\fs16 63 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 1716 [unit] \cell +\pard\intbl\qc\fs16 05JAN2014 (1) \cell +\pard\intbl\qc\fs16 25JAN2014 (400) \cell +\pard\intbl\qc\fs16 4795 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -1971,118 +1971,118 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1279 \cell -\pard\intbl\qc\fs16 72 / F / Unknown \cell +\pard\intbl\qc\fs16 01-706-1049 \cell +\pard\intbl\qc\fs16 60 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 3288 [unit] \cell +\pard\intbl\qc\fs16 15MAY2013 (1) \cell +\pard\intbl\qc\fs16 18JUN2013 (400) \cell +\pard\intbl\qc\fs16 3184 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1379 \cell -\pard\intbl\qc\fs16 81 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 3785 [unit] \cell +\pard\intbl\qc\fs16 22SEP2013 (1) \cell +\pard\intbl\qc\fs16 21SEP2013 (400) \cell +\pard\intbl\qc\fs16 1890 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1009 \cell -\pard\intbl\qc\fs16 83 / M / Unknown \cell +\pard\intbl\qc\fs16 01-708-1336 \cell +\pard\intbl\qc\fs16 73 / Male / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 2204 [unit] \cell +\pard\intbl\qc\fs16 08DEC2012 (1) \cell +\pard\intbl\qc\fs16 05JUN2013 (400) \cell +\pard\intbl\qc\fs16 2719 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1025 \cell -\pard\intbl\qc\fs16 81 / F / Asian \cell +\pard\intbl\qc\fs16 01-708-1347 \cell +\pard\intbl\qc\fs16 61 / Female / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 958 [unit] \cell +\pard\intbl\qc\fs16 21APR2013 (1) \cell +\pard\intbl\qc\fs16 18JUN2013 (200) \cell +\pard\intbl\qc\fs16 2588 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1114 \cell -\pard\intbl\qc\fs16 77 / M / Multiple \cell +\pard\intbl\qc\fs16 01-708-1372 \cell +\pard\intbl\qc\fs16 84 / Male / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 967 [unit] \cell +\pard\intbl\qc\fs16 13APR2013 (1) \cell +\pard\intbl\qc\fs16 19APR2013 (200) \cell +\pard\intbl\qc\fs16 3733 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -2091,46 +2091,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1120 \cell -\pard\intbl\qc\fs16 71 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-709-1029 \cell +\pard\intbl\qc\fs16 82 / Male / Other \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4345 [unit] \cell +\pard\intbl\qc\fs16 26DEC2012 (1) \cell +\pard\intbl\qc\fs16 26JUN2013 (50) \cell +\pard\intbl\qc\fs16 3697 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1135 \cell -\pard\intbl\qc\fs16 74 / F / Black or African American \cell +\pard\intbl\qc\fs16 01-709-1099 \cell +\pard\intbl\qc\fs16 79 / Female / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4027 [unit] \cell +\pard\intbl\qc\fs16 26OCT2013 (1) \cell +\pard\intbl\qc\fs16 25APR2014 (100) \cell +\pard\intbl\qc\fs16 4073 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -2139,70 +2139,70 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1218 \cell -\pard\intbl\qc\fs16 81 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-709-1238 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 3424 [unit] \cell +\pard\intbl\qc\fs16 16MAY2013 (1) \cell +\pard\intbl\qc\fs16 06AUG2013 (300) \cell +\pard\intbl\qc\fs16 2419 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1325 \cell -\pard\intbl\qc\fs16 81 / M / White \cell +\pard\intbl\qc\fs16 01-709-1309 \cell +\pard\intbl\qc\fs16 65 / Male / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 4663 [unit] \cell +\pard\intbl\qc\fs16 20JUN2013 (1) \cell +\pard\intbl\qc\fs16 19DEC2013 (50) \cell +\pard\intbl\qc\fs16 936 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1199 \cell -\pard\intbl\qc\fs16 87 / M / Black or African American \cell +\pard\intbl\qc\fs16 01-709-1329 \cell +\pard\intbl\qc\fs16 70 / Male / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 493 [unit] \cell +\pard\intbl\qc\fs16 16AUG2013 (1) \cell +\pard\intbl\qc\fs16 25AUG2013 (200) \cell +\pard\intbl\qc\fs16 4597 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -2211,22 +2211,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1292 \cell -\pard\intbl\qc\fs16 60 / F / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 01-710-1006 \cell +\pard\intbl\qc\fs16 77 / Male / Asian \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 815 [unit] \cell +\pard\intbl\qc\fs16 11FEB2013 (1) \cell +\pard\intbl\qc\fs16 09AUG2013 (300) \cell +\pard\intbl\qc\fs16 3395 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -2235,70 +2235,70 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1393 \cell -\pard\intbl\qc\fs16 84 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-710-1021 \cell +\pard\intbl\qc\fs16 79 / Male / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3762 [unit] \cell +\pard\intbl\qc\fs16 28SEP2013 (1) \cell +\pard\intbl\qc\fs16 29OCT2013 (100) \cell +\pard\intbl\qc\fs16 2838 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-706-1384 \cell -\pard\intbl\qc\fs16 74 / F / Multiple \cell +\pard\intbl\qc\fs16 01-710-1070 \cell +\pard\intbl\qc\fs16 85 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 4406 [unit] \cell +\pard\intbl\qc\fs16 09SEP2012 (1) \cell +\pard\intbl\qc\fs16 22JAN2013 (400) \cell +\pard\intbl\qc\fs16 1307 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1019 \cell -\pard\intbl\qc\fs16 68 / M / Asian \cell +\pard\intbl\qc\fs16 01-710-1137 \cell +\pard\intbl\qc\fs16 79 / Female / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 1177 [unit] \cell +\pard\intbl\qc\fs16 12OCT2013 (1) \cell +\pard\intbl\qc\fs16 13NOV2013 (200) \cell +\pard\intbl\qc\fs16 3437 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -2307,70 +2307,70 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1032 \cell -\pard\intbl\qc\fs16 62 / M / Multiple \cell +\pard\intbl\qc\fs16 01-710-1142 \cell +\pard\intbl\qc\fs16 76 / Female / Not reported \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 3770 [unit] \cell +\pard\intbl\qc\fs16 03OCT2012 (1) \cell +\pard\intbl\qc\fs16 20OCT2012 (50) \cell +\pard\intbl\qc\fs16 836 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1272 \cell -\pard\intbl\qc\fs16 82 / M / Not reported \cell +\pard\intbl\qc\fs16 01-710-1187 \cell +\pard\intbl\qc\fs16 78 / Female / Unknown \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 200 \cell -\pard\intbl\qc\fs16 201 [unit] \cell +\pard\intbl\qc\fs16 11NOV2012 (1) \cell +\pard\intbl\qc\fs16 12MAY2013 (200) \cell +\pard\intbl\qc\fs16 2514 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 No \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1297 \cell -\pard\intbl\qc\fs16 61 / M / Not reported \cell +\pard\intbl\qc\fs16 01-710-1278 \cell +\pard\intbl\qc\fs16 81 / Male / Asian \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 300 \cell -\pard\intbl\qc\fs16 3732 [unit] \cell +\pard\intbl\qc\fs16 25DEC2012 (1) \cell +\pard\intbl\qc\fs16 26FEB2013 (50) \cell +\pard\intbl\qc\fs16 2316 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -2379,22 +2379,22 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1348 \cell -\pard\intbl\qc\fs16 79 / F / Multiple \cell +\pard\intbl\qc\fs16 01-710-1408 \cell +\pard\intbl\qc\fs16 80 / Male / Multiple \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 400 \cell -\pard\intbl\qc\fs16 3914 [unit] \cell +\pard\intbl\qc\fs16 06JAN2013 (1) \cell +\pard\intbl\qc\fs16 12JUL2013 (400) \cell +\pard\intbl\qc\fs16 4107 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 No \cell @@ -2403,46 +2403,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1353 \cell -\pard\intbl\qc\fs16 87 / F / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 01-711-1012 \cell +\pard\intbl\qc\fs16 67 / Female / Native Hawaiian or other Pacific Islander \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 50 \cell -\pard\intbl\qc\fs16 967 [unit] \cell +\pard\intbl\qc\fs16 04APR2013 (1) \cell +\pard\intbl\qc\fs16 29APR2013 (100) \cell +\pard\intbl\qc\fs16 1241 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Yes \cell +\pard\intbl\qc\fs16 Yes \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4813 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6284 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7175 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8958 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9849 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10963 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx956 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1548 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4598 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5418 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6465 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7967 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8877 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9788 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10926 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1081 \cell -\pard\intbl\qc\fs16 86 / F / White \cell +\pard\intbl\qc\fs16 01-711-1433 \cell +\pard\intbl\qc\fs16 84 / Female / Asian \cell \pard\intbl\qc\fs16 Last Treatment Visit \cell -\pard\intbl\qc\fs16 1 \cell -\pard\intbl\qc\fs16 100 \cell -\pard\intbl\qc\fs16 4439 [unit] \cell +\pard\intbl\qc\fs16 28JAN2013 (1) \cell +\pard\intbl\qc\fs16 05FEB2013 (50) \cell +\pard\intbl\qc\fs16 3732 mg \cell \pard\intbl\qc\fs16 Unblind Reason \cell \pard\intbl\qc\fs16 Yes \cell \pard\intbl\qc\fs16 Yes \cell @@ -2451,15 +2451,15 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4813 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6284 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7175 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8423 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8958 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9849 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10963 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx956 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1548 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4598 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5418 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6465 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7967 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8877 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9788 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10926 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2475,15 +2475,15 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4813 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6284 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7175 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8958 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9849 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10963 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx956 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1548 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4598 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5418 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6465 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7967 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8877 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9788 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10926 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/lsids04/lsids04.rtf b/tests/testthat/_snaps/lsids04/lsids04.rtf old mode 100755 new mode 100644 index b87a5ee9..8d9c6cc7 --- a/tests/testthat/_snaps/lsids04/lsids04.rtf +++ b/tests/testthat/_snaps/lsids04/lsids04.rtf @@ -3,9 +3,9 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3557 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5758 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8806 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7131 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8579 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIDS04:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -15,21 +15,21 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3557 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5758 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8806 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7131 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8579 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell -\pard\intbl\qc\fs16 \keepn\trhdr Primary Reason for no Treatment \cell +\pard\intbl\qc\fs16 \keepn\trhdr Primary Reason Not Treated \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3557 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5758 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8806 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7131 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8579 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10584 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 No data to report \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell @@ -39,9 +39,9 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3557 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5758 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8806 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7131 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8579 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10584 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -51,9 +51,9 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3557 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5758 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8806 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7131 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8579 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10584 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/lsids05/lsids05.rtf b/tests/testthat/_snaps/lsids05/lsids05.rtf old mode 100755 new mode 100644 index bdb817e5..fff513f5 --- a/tests/testthat/_snaps/lsids05/lsids05.rtf +++ b/tests/testthat/_snaps/lsids05/lsids05.rtf @@ -3,51 +3,41 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3849 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8275 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5908 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIDS05:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3849 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8275 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5908 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr First Contact in the Study\super a\nosupersub \cell -\pard\intbl\qc\fs16 \keepn\trhdr Last Visit in the Study\super b\nosupersub \cell -\pard\intbl\qc\fs16 \keepn\trhdr Last Contact in the Study\super c\nosupersub \cell +\pard\intbl\qc\fs16 \keepn\trhdr Last Contact/Visit in the Study\super b\nosupersub \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3849 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8275 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5908 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 06JUL2012 \cell \pard\intbl\qc\fs16 05MAR2015 \cell -\pard\intbl\qc\fs16 05MAR2015 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3849 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8275 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5908 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3849 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8275 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5908 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell -\pard\intbl\qc \cell \row } \par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} diff --git a/tests/testthat/_snaps/lsiex01/lsiex01.rtf b/tests/testthat/_snaps/lsiex01/lsiex01.rtf old mode 100755 new mode 100644 index 9fca1ebb..c898c2e7 --- a/tests/testthat/_snaps/lsiex01/lsiex01.rtf +++ b/tests/testthat/_snaps/lsiex01/lsiex01.rtf @@ -3,16 +3,17 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx974 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1577 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2411 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3384 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4265 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4729 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8112 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9271 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10430 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11728 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2986 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3922 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4947 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6685 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8111 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9582 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10473 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11587 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIEX01:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -24,2647 +25,2851 @@ \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx974 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1577 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2411 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3384 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4265 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4729 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8112 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9271 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10430 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11728 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2986 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3922 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4947 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6685 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8111 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9582 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10473 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11587 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell -\pard\intbl\qc\fs16 \keepn\trhdr Visit \cell -\pard\intbl\qc\fs16 \keepn\trhdr Prescribed Dose Level (unit) \cell -\pard\intbl\qc\fs16 \keepn\trhdr Dose (unit) \cell -\pard\intbl\qc\fs16 \keepn\trhdr Formulation / Frequency / Route \cell +\pard\intbl\qc\fs16 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs16 \keepn\trhdr Prescribed Dose (unit) / Frequency \cell +\pard\intbl\qc\fs16 \keepn\trhdr Formulation / Route \cell +\pard\intbl\qc\fs16 \keepn\trhdr Action Taken to Prescribed Dose\super a\nosupersub / Reason \cell +\pard\intbl\qc\fs16 \keepn\trhdr Dose Delayed? / Reason \cell +\pard\intbl\qc\fs16 \keepn\trhdr Action Taken With Study Treatment / Reason \cell +\pard\intbl\qc\fs16 \keepn\trhdr Actual Dose (unit) / Frequency \cell \pard\intbl\qc\fs16 \keepn\trhdr Start Date / Time (Study Day\super a\nosupersub ) \cell -\pard\intbl\qc\fs16 \keepn\trhdr End Date / Time (Study Day\super a\nosupersub ) \cell -\pard\intbl\qc\fs16 \keepn\trhdr Reason Dose Not Administered, if Applicable \cell -\pard\intbl\qc\fs16 \keepn\trhdr Reason Dose Adjusted, if Applicable \cell +\pard\intbl\qc\fs16 \keepn\trhdr End Date / (Study Day\super a\nosupersub ) \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 71 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 19JUL2013 / 03:00 (1) \cell -\pard\intbl\qc\fs16 01AUG2013 / --:-- (14) \cell -\pard\intbl\qc\fs16 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Diarrhoea) \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 18MAR2014 / 15:00 (1) \cell +\pard\intbl\qc\fs16 31MAR2014 / (14) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1097 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 02AUG2013 / 10:00 (15) \cell -\pard\intbl\qc\fs16 06JAN2014 / --:-- (172) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 01JAN2014 / 07:00 (1) \cell +\pard\intbl\qc\fs16 15JAN2014 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 300 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 07JAN2014 / 11:00 (173) \cell -\pard\intbl\qc\fs16 14JAN2014 / --:-- (180) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 16JAN2014 / 15:00 (16) \cell +\pard\intbl\qc\fs16 18JUN2014 / (169) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 77 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 01JUL2014 / 17:00 (1) \cell -\pard\intbl\qc\fs16 15JUL2014 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 19JUN2014 / 18:00 (170) \cell +\pard\intbl\qc\fs16 09JUL2014 / (190) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 0 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 16JUL2014 / 10:00 (16) \cell -\pard\intbl\qc\fs16 17DEC2014 / --:-- (170) \cell -\pard\intbl\qc\fs16 Adverse event \cell -\pard\intbl\qc\fs16 Adverse event \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Nausea, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 07SEP2012 / 11:00 (1) \cell +\pard\intbl\qc\fs16 16SEP2012 / (10) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 0 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 18DEC2014 / 07:00 (171) \cell -\pard\intbl\qc\fs16 30DEC2014 / --:-- (183) \cell -\pard\intbl\qc\fs16 Adverse event \cell -\pard\intbl\qc\fs16 Adverse event \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Due to personal schedule \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 30NOV2012 / 17:00 (1) \cell +\pard\intbl\qc\fs16 13DEC2012 / (14) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1133 \cell -\pard\intbl\qc\fs16 81 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 28OCT2012 / 08:00 (1) \cell -\pard\intbl\qc\fs16 12NOV2012 / --:-- (16) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 14DEC2012 / 17:00 (15) \cell +\pard\intbl\qc\fs16 23JAN2013 / (55) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 13NOV2012 / 08:00 (17) \cell -\pard\intbl\qc\fs16 18APR2013 / --:-- (173) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Personal reasons \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 05DEC2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 09DEC2013 / (5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 19APR2013 / 00:00 (174) \cell -\pard\intbl\qc\fs16 28APR2013 / --:-- (183) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 15FEB2013 / 10:00 (1) \cell +\pard\intbl\qc\fs16 02MAR2013 / (16) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1146 \cell -\pard\intbl\qc\fs16 75 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 20MAY2013 / 17:00 (1) \cell -\pard\intbl\qc\fs16 03JUN2013 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 03MAR2013 / 15:00 (17) \cell +\pard\intbl\qc\fs16 24MAR2013 / (38) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 04JUN2013 / 05:00 (16) \cell -\pard\intbl\qc\fs16 26JUN2013 / --:-- (38) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 22JUL2012 / 00:00 (1) \cell +\pard\intbl\qc\fs16 07AUG2012 / (17) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1148 \cell -\pard\intbl\qc\fs16 57 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 23AUG2013 / 01:00 (1) \cell -\pard\intbl\qc\fs16 05SEP2013 / --:-- (14) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 08AUG2012 / 10:00 (18) \cell +\pard\intbl\qc\fs16 11JAN2013 / (174) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 06SEP2013 / 12:00 (15) \cell -\pard\intbl\qc\fs16 08FEB2014 / --:-- (170) \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 12JAN2013 / 03:00 (175) \cell +\pard\intbl\qc\fs16 20JAN2013 / (183) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 0 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 09FEB2014 / 10:00 (171) \cell -\pard\intbl\qc\fs16 20FEB2014 / --:-- (182) \cell -\pard\intbl\qc\fs16 Other: Other reason \cell -\pard\intbl\qc\fs16 Other: Sheet could not into the bladder \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 15NOV2012 / 05:00 (1) \cell +\pard\intbl\qc\fs16 28NOV2012 / (14) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1180 \cell -\pard\intbl\qc\fs16 56 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 12FEB2013 / 02:00 (1) \cell -\pard\intbl\qc\fs16 25FEB2013 / --:-- (14) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 29NOV2012 / 19:00 (15) \cell +\pard\intbl\qc\fs16 12JAN2013 / (59) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 67 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 26FEB2013 / 04:00 (15) \cell -\pard\intbl\qc\fs16 18MAR2013 / --:-- (35) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 24MAR2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 10APR2013 / (18) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1239 \cell -\pard\intbl\qc\fs16 56 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 11JAN2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 25JAN2014 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Physician decision \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 11APR2013 / 19:00 (19) \cell +\pard\intbl\qc\fs16 14JUN2013 / (83) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Headache, Anaemia) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 26JAN2014 / 05:00 (16) \cell -\pard\intbl\qc\fs16 27JUN2014 / --:-- (168) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 22MAY2014 / 13:00 (1) \cell +\pard\intbl\qc\fs16 05JUN2014 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 28JUN2014 / 15:00 (169) \cell -\pard\intbl\qc\fs16 10JUL2014 / --:-- (181) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Progression \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 06JUN2014 / 09:00 (16) \cell +\pard\intbl\qc\fs16 06NOV2014 / (169) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1275 \cell -\pard\intbl\qc\fs16 61 / Male / American Indian or Alaska Native \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 07FEB2014 / 00:00 (1) \cell -\pard\intbl\qc\fs16 22FEB2014 / --:-- (16) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 07NOV2014 / 07:00 (170) \cell +\pard\intbl\qc\fs16 20NOV2014 / (183) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 23FEB2014 / 02:00 (17) \cell -\pard\intbl\qc\fs16 31MAY2014 / --:-- (114) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Headache, Pyrexia) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 02OCT2012 / 03:00 (1) \cell +\pard\intbl\qc\fs16 16OCT2012 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1287 \cell -\pard\intbl\qc\fs16 56 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 25JAN2014 / 22:00 (1) \cell -\pard\intbl\qc\fs16 11FEB2014 / --:-- (18) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Other medical reason \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 17OCT2012 / 18:00 (16) \cell +\pard\intbl\qc\fs16 19MAR2013 / (169) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 12FEB2014 / 22:00 (19) \cell -\pard\intbl\qc\fs16 12JUL2014 / --:-- (169) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 20MAR2013 / 01:00 (170) \cell +\pard\intbl\qc\fs16 02APR2013 / (183) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 51 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 13JUL2014 / 18:00 (170) \cell -\pard\intbl\qc\fs16 26JUL2014 / --:-- (183) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 05JAN2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 18JAN2013 / (14) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1302 \cell -\pard\intbl\qc\fs16 61 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 29AUG2013 / 03:00 (1) \cell -\pard\intbl\qc\fs16 15SEP2013 / --:-- (18) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Tar-200 did not take the pretzel shape inside the bladder. \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 19JAN2013 / 08:00 (15) \cell +\pard\intbl\qc\fs16 26JAN2013 / (22) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 67 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Rash, Anaemia) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 16SEP2013 / 20:00 (19) \cell -\pard\intbl\qc\fs16 05NOV2013 / --:-- (69) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 31JUL2013 / 11:00 (1) \cell +\pard\intbl\qc\fs16 05AUG2013 / (6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1383 \cell -\pard\intbl\qc\fs16 72 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 04FEB2013 / 16:00 (1) \cell -\pard\intbl\qc\fs16 19FEB2013 / --:-- (16) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 19MAR2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 02APR2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 20FEB2013 / 01:00 (17) \cell -\pard\intbl\qc\fs16 30JUL2013 / --:-- (177) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 03APR2013 / 02:00 (16) \cell +\pard\intbl\qc\fs16 30APR2013 / (43) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 300 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 31JUL2013 / 07:00 (178) \cell -\pard\intbl\qc\fs16 06AUG2013 / --:-- (184) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1442 \cell +\pard\intbl\qc\fs16 57 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 26OCT2013 / 09:00 (1) \cell +\pard\intbl\qc\fs16 09NOV2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1444 \cell -\pard\intbl\qc\fs16 63 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 05JAN2013 / 09:00 (1) \cell -\pard\intbl\qc\fs16 18JAN2013 / --:-- (14) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 10NOV2013 / 05:00 (16) \cell +\pard\intbl\qc\fs16 17APR2014 / (174) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 19JAN2013 / 16:00 (15) \cell -\pard\intbl\qc\fs16 12FEB2013 / --:-- (39) \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Fatigue, Neutropenia) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 18APR2014 / 11:00 (175) \cell +\pard\intbl\qc\fs16 26APR2014 / (183) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1076 \cell -\pard\intbl\qc\fs16 69 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 25OCT2013 / 16:00 (1) \cell -\pard\intbl\qc\fs16 06NOV2013 / --:-- (13) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-702-1082 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 26JUL2013 / 13:00 (1) \cell +\pard\intbl\qc\fs16 08AUG2013 / (14) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 07NOV2013 / 05:00 (14) \cell -\pard\intbl\qc\fs16 24DEC2013 / --:-- (61) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 09AUG2013 / 13:00 (15) \cell +\pard\intbl\qc\fs16 13OCT2013 / (80) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1258 \cell -\pard\intbl\qc\fs16 78 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 20JUL2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 01AUG2012 / --:-- (13) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-703-1086 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 02SEP2012 / 08:00 (1) \cell +\pard\intbl\qc\fs16 16SEP2012 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 02AUG2012 / 18:00 (14) \cell -\pard\intbl\qc\fs16 31DEC2012 / --:-- (165) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Other medical reason \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 17SEP2012 / 10:00 (16) \cell +\pard\intbl\qc\fs16 04DEC2012 / (94) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 01JAN2013 / 17:00 (166) \cell -\pard\intbl\qc\fs16 11JAN2013 / --:-- (176) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 20FEB2013 / 17:00 (1) \cell +\pard\intbl\qc\fs16 10MAR2013 / (19) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1295 \cell -\pard\intbl\qc\fs16 88 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 21NOV2013 / 13:00 (1) \cell -\pard\intbl\qc\fs16 05DEC2013 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 Y / Other: Site closure \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 11MAR2013 / 02:00 (20) \cell +\pard\intbl\qc\fs16 13JUN2013 / (114) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 06DEC2013 / 05:00 (16) \cell -\pard\intbl\qc\fs16 19APR2014 / --:-- (150) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Subject request \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 17OCT2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 31OCT2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1335 \cell -\pard\intbl\qc\fs16 67 / Female / Black or African American \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 17MAR2014 / 10:00 (1) \cell -\pard\intbl\qc\fs16 31MAR2014 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 01NOV2013 / 22:00 (16) \cell +\pard\intbl\qc\fs16 11DEC2013 / (56) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 01APR2014 / 16:00 (16) \cell -\pard\intbl\qc\fs16 07MAY2014 / --:-- (52) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 76 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 16JUN2013 / 07:00 (1) \cell +\pard\intbl\qc\fs16 29JUN2013 / (14) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1439 \cell -\pard\intbl\qc\fs16 76 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 12MAR2014 / 11:00 (1) \cell -\pard\intbl\qc\fs16 26MAR2014 / --:-- (15) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-703-1279 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 13MAY2013 / 00:00 (1) \cell +\pard\intbl\qc\fs16 03JUN2013 / (22) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1379 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Subject request \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 27MAR2014 / 12:00 (16) \cell -\pard\intbl\qc\fs16 28AUG2014 / --:-- (170) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 22SEP2013 / 02:00 (1) \cell +\pard\intbl\qc\fs16 07OCT2013 / (16) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 29AUG2014 / 17:00 (171) \cell -\pard\intbl\qc\fs16 11SEP2014 / --:-- (184) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 Y / Other: Equipment malfunction \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Suspicion of disease progression \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 08OCT2013 / 12:00 (17) \cell +\pard\intbl\qc\fs16 08MAR2014 / (168) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1008 \cell -\pard\intbl\qc\fs16 76 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 13JAN2013 / 16:00 (1) \cell -\pard\intbl\qc\fs16 28JAN2013 / --:-- (16) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose re-escalated / Medical reason \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 09MAR2014 / 18:00 (169) \cell +\pard\intbl\qc\fs16 21MAR2014 / (181) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 29JAN2013 / 00:00 (17) \cell -\pard\intbl\qc\fs16 21FEB2013 / --:-- (40) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-703-1403 \cell +\pard\intbl\qc\fs16 67 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 12DEC2012 / 15:00 (1) \cell +\pard\intbl\qc\fs16 13DEC2012 / (2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1017 \cell -\pard\intbl\qc\fs16 77 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 06OCT2013 / 00:00 (1) \cell -\pard\intbl\qc\fs16 19OCT2013 / --:-- (14) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1009 \cell +\pard\intbl\qc\fs16 83 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 27AUG2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 14SEP2013 / (19) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 20OCT2013 / 17:00 (15) \cell -\pard\intbl\qc\fs16 18NOV2013 / --:-- (44) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Administrative reason \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 15SEP2013 / 22:00 (20) \cell +\pard\intbl\qc\fs16 25SEP2013 / (30) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1065 \cell -\pard\intbl\qc\fs16 75 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 24OCT2013 / 21:00 (1) \cell -\pard\intbl\qc\fs16 07NOV2013 / --:-- (15) \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 27SEP2013 / 11:00 (1) \cell +\pard\intbl\qc\fs16 11OCT2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 08NOV2013 / 01:00 (16) \cell -\pard\intbl\qc\fs16 22DEC2013 / --:-- (60) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 12OCT2013 / 08:00 (16) \cell +\pard\intbl\qc\fs16 24OCT2013 / (28) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1074 \cell -\pard\intbl\qc\fs16 80 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 22JAN2014 / 20:00 (1) \cell -\pard\intbl\qc\fs16 09FEB2014 / --:-- (19) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 23JAN2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 03FEB2013 / (12) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 10FEB2014 / 09:00 (20) \cell -\pard\intbl\qc\fs16 20MAR2014 / --:-- (58) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Physician decision \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 04FEB2013 / 20:00 (13) \cell +\pard\intbl\qc\fs16 07JUL2013 / (166) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1093 \cell -\pard\intbl\qc\fs16 79 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 15MAR2013 / 10:00 (1) \cell -\pard\intbl\qc\fs16 30MAR2013 / --:-- (16) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 02DEC2013 / 05:00 (1) \cell +\pard\intbl\qc\fs16 15DEC2013 / (14) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 31MAR2013 / 07:00 (17) \cell -\pard\intbl\qc\fs16 17JUN2013 / --:-- (95) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 16DEC2013 / 08:00 (15) \cell +\pard\intbl\qc\fs16 01FEB2014 / (62) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1241 \cell -\pard\intbl\qc\fs16 86 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 25AUG2013 / 19:00 (1) \cell -\pard\intbl\qc\fs16 05SEP2013 / --:-- (12) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1135 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 31OCT2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 14NOV2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 06SEP2013 / 08:00 (13) \cell -\pard\intbl\qc\fs16 09OCT2013 / --:-- (46) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 15NOV2013 / 20:00 (16) \cell +\pard\intbl\qc\fs16 01MAY2014 / (183) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1266 \cell -\pard\intbl\qc\fs16 82 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 13OCT2013 / 20:00 (1) \cell -\pard\intbl\qc\fs16 27OCT2013 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 02MAY2014 / 19:00 (184) \cell +\pard\intbl\qc\fs16 16MAY2014 / (198) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 28OCT2013 / 11:00 (16) \cell -\pard\intbl\qc\fs16 06DEC2013 / --:-- (55) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 19NOV2012 / 21:00 (1) \cell +\pard\intbl\qc\fs16 03DEC2012 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1332 \cell -\pard\intbl\qc\fs16 80 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 09DEC2013 / 11:00 (1) \cell -\pard\intbl\qc\fs16 23DEC2013 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 04DEC2012 / 05:00 (16) \cell +\pard\intbl\qc\fs16 13MAY2013 / (176) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 24DEC2013 / 06:00 (16) \cell -\pard\intbl\qc\fs16 14FEB2014 / --:-- (68) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Subject request \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 14MAY2013 / 14:00 (177) \cell +\pard\intbl\qc\fs16 27MAY2013 / (190) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1280 \cell -\pard\intbl\qc\fs16 56 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 17JAN2014 / 01:00 (1) \cell -\pard\intbl\qc\fs16 31JAN2014 / --:-- (15) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 68 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 08JUL2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 23JUL2013 / (16) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 01FEB2014 / 22:00 (16) \cell -\pard\intbl\qc\fs16 11JUL2014 / --:-- (176) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 24JUL2013 / 09:00 (17) \cell +\pard\intbl\qc\fs16 05AUG2013 / (29) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 12JUL2014 / 01:00 (177) \cell -\pard\intbl\qc\fs16 25JUL2014 / --:-- (190) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 23APR2014 / 05:00 (1) \cell +\pard\intbl\qc\fs16 07MAY2014 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1281 \cell -\pard\intbl\qc\fs16 73 / Female / Black or African American \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 28NOV2013 / 00:00 (1) \cell -\pard\intbl\qc\fs16 15DEC2013 / --:-- (18) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 08MAY2014 / 12:00 (16) \cell +\pard\intbl\qc\fs16 04JUL2014 / (73) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 16DEC2013 / 07:00 (19) \cell -\pard\intbl\qc\fs16 27FEB2014 / --:-- (92) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Dose re-escalated / Physician decision \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 27NOV2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 18DEC2013 / (22) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1303 \cell -\pard\intbl\qc\fs16 72 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 16DEC2013 / 12:00 (1) \cell -\pard\intbl\qc\fs16 30DEC2013 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 19DEC2013 / 17:00 (23) \cell +\pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 87 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 31DEC2013 / 22:00 (16) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Pqc \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 16SEP2013 / 09:00 (1) \cell +\pard\intbl\qc\fs16 28SEP2013 / (13) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1310 \cell -\pard\intbl\qc\fs16 74 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 02NOV2013 / 13:00 (1) \cell -\pard\intbl\qc\fs16 22NOV2013 / --:-- (21) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-705-1292 \cell +\pard\intbl\qc\fs16 60 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 14OCT2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 29OCT2013 / (16) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 23NOV2013 / 23:00 (22) \cell -\pard\intbl\qc\fs16 23JAN2014 / --:-- (83) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Personal reasons \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 30OCT2013 / 00:00 (17) \cell +\pard\intbl\qc\fs16 28APR2014 / (197) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1377 \cell -\pard\intbl\qc\fs16 63 / Female / Black or African American \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 04JAN2014 / 08:00 (1) \cell -\pard\intbl\qc\fs16 25JAN2014 / --:-- (22) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 29APR2014 / 18:00 (198) \cell +\pard\intbl\qc\fs16 13MAY2014 / (212) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 26JAN2014 / 21:00 (23) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-705-1382 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Bladder mapping performed on 20 nov 2023 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 13MAY2013 / 15:00 (1) \cell \pard\intbl\qc\fs16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-706-1049 \cell -\pard\intbl\qc\fs16 60 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 14MAY2013 / 01:00 (1) \cell -\pard\intbl\qc\fs16 28MAY2013 / --:-- (15) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-705-1393 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 07SEP2012 / 07:00 (1) \cell +\pard\intbl\qc\fs16 27SEP2012 / (21) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 29MAY2013 / 01:00 (16) \cell -\pard\intbl\qc\fs16 18JUN2013 / --:-- (36) \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 28SEP2012 / 13:00 (22) \cell +\pard\intbl\qc\fs16 01FEB2013 / (148) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1178 \cell -\pard\intbl\qc\fs16 77 / Female / Black or African American \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 29DEC2013 / 16:00 (1) \cell -\pard\intbl\qc\fs16 18JAN2014 / --:-- (21) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-705-1431 \cell +\pard\intbl\qc\fs16 68 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 23JUN2013 / 15:00 (1) \cell +\pard\intbl\qc\fs16 07JUL2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 19JAN2014 / 23:00 (22) \cell -\pard\intbl\qc\fs16 06APR2014 / --:-- (99) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 08JUL2013 / 21:00 (16) \cell +\pard\intbl\qc\fs16 05DEC2013 / (166) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1216 \cell -\pard\intbl\qc\fs16 78 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 24OCT2012 / 08:00 (1) \cell -\pard\intbl\qc\fs16 08NOV2012 / --:-- (16) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 06DEC2013 / 04:00 (167) \cell +\pard\intbl\qc\fs16 19DEC2013 / (180) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 09NOV2012 / 05:00 (17) \cell -\pard\intbl\qc\fs16 29NOV2012 / --:-- (37) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-706-1384 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 15SEP2012 / 13:00 (1) \cell +\pard\intbl\qc\fs16 24SEP2012 / (10) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1336 \cell -\pard\intbl\qc\fs16 73 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 07DEC2012 / 03:00 (1) \cell -\pard\intbl\qc\fs16 21DEC2012 / --:-- (15) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 20DEC2013 / 08:00 (1) \cell +\pard\intbl\qc\fs16 24DEC2013 / (5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1019 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 22DEC2012 / 09:00 (16) \cell -\pard\intbl\qc\fs16 22MAY2013 / --:-- (167) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 20DEC2013 / 00:00 (1) \cell +\pard\intbl\qc\fs16 01JAN2014 / (13) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1032 \cell +\pard\intbl\qc\fs16 62 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 23MAY2013 / 18:00 (168) \cell -\pard\intbl\qc\fs16 05JUN2013 / --:-- (181) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 09FEB2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 23FEB2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1347 \cell -\pard\intbl\qc\fs16 61 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 20APR2013 / 07:00 (1) \cell -\pard\intbl\qc\fs16 04MAY2013 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 24FEB2013 / 19:00 (16) \cell +\pard\intbl\qc\fs16 01MAR2013 / (21) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1084 \cell +\pard\intbl\qc\fs16 73 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 05MAY2013 / 19:00 (16) \cell -\pard\intbl\qc\fs16 18JUN2013 / --:-- (60) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 09MAY2013 / 05:00 (1) \cell +\pard\intbl\qc\fs16 23MAY2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1406 \cell -\pard\intbl\qc\fs16 71 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 26DEC2013 / 15:00 (1) \cell -\pard\intbl\qc\fs16 09JAN2014 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 24MAY2013 / 20:00 (16) \cell +\pard\intbl\qc\fs16 28OCT2013 / (173) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 10JAN2014 / 12:00 (16) \cell -\pard\intbl\qc\fs16 16JUN2014 / --:-- (173) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: The dose delayed due to turb performed 10-nov-2023 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 29OCT2013 / 11:00 (174) \cell +\pard\intbl\qc\fs16 11NOV2013 / (187) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1213 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 17JUN2014 / 11:00 (174) \cell -\pard\intbl\qc\fs16 02JUL2014 / --:-- (189) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 09FEB2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 22FEB2013 / (14) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1029 \cell -\pard\intbl\qc\fs16 82 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 25DEC2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 09JAN2013 / --:-- (16) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 21SEP2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 21SEP2013 / (1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 10JAN2013 / 04:00 (17) \cell -\pard\intbl\qc\fs16 12JUN2013 / --:-- (170) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 06FEB2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 21FEB2013 / (16) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 13JUN2013 / 01:00 (171) \cell -\pard\intbl\qc\fs16 26JUN2013 / --:-- (184) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 22FEB2013 / 01:00 (17) \cell +\pard\intbl\qc\fs16 22MAR2013 / (45) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1099 \cell -\pard\intbl\qc\fs16 79 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 25OCT2013 / 03:00 (1) \cell -\pard\intbl\qc\fs16 12NOV2013 / --:-- (19) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 61 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 25JAN2013 / 11:00 (1) \cell +\pard\intbl\qc\fs16 08FEB2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 13NOV2013 / 03:00 (20) \cell -\pard\intbl\qc\fs16 11APR2014 / --:-- (169) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Personal reasons \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 09FEB2013 / 00:00 (16) \cell +\pard\intbl\qc\fs16 03MAY2013 / (99) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1348 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 12APR2014 / 09:00 (170) \cell -\pard\intbl\qc\fs16 25APR2014 / --:-- (183) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 05AUG2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 19AUG2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1168 \cell -\pard\intbl\qc\fs16 72 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 02AUG2013 / 13:00 (1) \cell -\pard\intbl\qc\fs16 17AUG2013 / --:-- (16) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 20AUG2013 / 07:00 (16) \cell +\pard\intbl\qc\fs16 03FEB2014 / (183) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 18AUG2013 / 03:00 (17) \cell -\pard\intbl\qc\fs16 26SEP2013 / --:-- (56) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 8 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 04FEB2014 / 14:00 (184) \cell +\pard\intbl\qc\fs16 13FEB2014 / (193) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1238 \cell -\pard\intbl\qc\fs16 69 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 15MAY2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 29MAY2013 / --:-- (15) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-708-1353 \cell +\pard\intbl\qc\fs16 87 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 04JUL2013 / 13:00 (1) \cell +\pard\intbl\qc\fs16 18JUL2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 30MAY2013 / 16:00 (16) \cell -\pard\intbl\qc\fs16 06AUG2013 / --:-- (84) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Pt had his 24w turb on 22th of december so tar was removed at that time \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 19JUL2013 / 01:00 (16) \cell +\pard\intbl\qc\fs16 28AUG2013 / (56) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1309 \cell -\pard\intbl\qc\fs16 65 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 19JUN2013 / 13:00 (1) \cell -\pard\intbl\qc\fs16 01JUL2013 / --:-- (13) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-708-1372 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Oral \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 12APR2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 19APR2013 / (8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1428 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 02JUL2013 / 19:00 (14) \cell -\pard\intbl\qc\fs16 05DEC2013 / --:-- (170) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Y / Other: Site closure \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Rash, Pyrexia) \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 09NOV2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 23NOV2013 / (15) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 06DEC2013 / 16:00 (171) \cell -\pard\intbl\qc\fs16 19DEC2013 / --:-- (184) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 24NOV2013 / 12:00 (16) \cell +\pard\intbl\qc\fs16 14DEC2013 / (36) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1006 \cell -\pard\intbl\qc\fs16 77 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 10FEB2013 / 07:00 (1) \cell -\pard\intbl\qc\fs16 22FEB2013 / --:-- (13) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-709-1007 \cell +\pard\intbl\qc\fs16 54 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Transdermal \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 31JUL2012 / 19:00 (1) \cell +\pard\intbl\qc\fs16 18AUG2012 / (19) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 23FEB2013 / 02:00 (14) \cell -\pard\intbl\qc\fs16 27JUL2013 / --:-- (168) \cell +\pard\intbl\qc\fs16 Evening dose 1 \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Infusion \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 19AUG2012 / 19:00 (20) \cell +\pard\intbl\qc\fs16 28AUG2012 / (29) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx974 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1577 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2411 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3384 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4265 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4729 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8112 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9271 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10430 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11728 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2986 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4947 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6685 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8111 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9582 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10473 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11587 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 Patch / QD / Transdermal \cell -\pard\intbl\qc\fs16 28JUL2013 / 05:00 (169) \cell -\pard\intbl\qc\fs16 09AUG2013 / --:-- (181) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx974 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1577 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2411 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3384 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4265 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4729 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8112 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9271 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10430 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11728 +\pard\intbl\qc\fs16 01-709-1020 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Morning dose \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 Patch / Injection \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 mg / QD \cell +\pard\intbl\qc\fs16 01DEC2012 / 19:00 (1) \cell +\pard\intbl\qc\fs16 15DEC2012 / (15) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2986 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3922 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4947 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6685 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8111 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9582 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10473 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11587 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2676,21 +2881,23 @@ \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx974 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1577 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2411 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3384 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4265 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4729 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8112 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9271 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10430 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11728 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2986 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4947 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6685 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8111 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9582 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10473 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell @@ -2702,6 +2909,7 @@ \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } \par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} diff --git a/tests/testthat/_snaps/lsiex02/lsiex02.rtf b/tests/testthat/_snaps/lsiex02/lsiex02.rtf old mode 100755 new mode 100644 index 94fd7a17..6a75182f --- a/tests/testthat/_snaps/lsiex02/lsiex02.rtf +++ b/tests/testthat/_snaps/lsiex02/lsiex02.rtf @@ -3,12 +3,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2214 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5244 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6255 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7361 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8468 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11595 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2924 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5803 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6579 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7630 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8681 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11651 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIEX02:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,12 +21,12 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2214 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5244 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6255 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7361 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8468 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11595 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2924 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5803 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6579 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7630 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8681 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11651 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Visit \cell @@ -39,17 +39,35 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 19JUL2013 \cell -\pard\intbl\qc\fs16 03:00 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 18MAR2014 \cell +\pard\intbl\qc\fs16 15:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1097 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 01JAN2014 \cell +\pard\intbl\qc\fs16 07:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell \row @@ -57,53 +75,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 02AUG2013 \cell -\pard\intbl\qc\fs16 10:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 16JAN2014 \cell +\pard\intbl\qc\fs16 15:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 07JAN2014 \cell -\pard\intbl\qc\fs16 11:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 19JUN2014 \cell +\pard\intbl\qc\fs16 18:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 01JUL2014 \cell -\pard\intbl\qc\fs16 17:00 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 07SEP2012 \cell +\pard\intbl\qc\fs16 11:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -111,53 +129,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 16JUL2014 \cell -\pard\intbl\qc\fs16 10:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs16 20MAR2014 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 30NOV2012 \cell +\pard\intbl\qc\fs16 17:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 18DEC2014 \cell -\pard\intbl\qc\fs16 07:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 14DEC2012 \cell +\pard\intbl\qc\fs16 17:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1133 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 28OCT2012 \cell -\pard\intbl\qc\fs16 08:00 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 05DEC2013 \cell +\pard\intbl\qc\fs16 23:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell \pard\intbl\qc\fs16 20MAR2014 \cell \row @@ -165,53 +183,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 13NOV2012 \cell -\pard\intbl\qc\fs16 08:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 15FEB2013 \cell +\pard\intbl\qc\fs16 10:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 19APR2013 \cell -\pard\intbl\qc\fs16 00:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 03MAR2013 \cell +\pard\intbl\qc\fs16 15:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1146 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 20MAY2013 \cell -\pard\intbl\qc\fs16 17:00 \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 22JUL2012 \cell +\pard\intbl\qc\fs16 00:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell \row @@ -219,17 +237,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 04JUN2013 \cell -\pard\intbl\qc\fs16 05:00 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 08AUG2012 \cell +\pard\intbl\qc\fs16 10:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -237,35 +255,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1148 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 23AUG2013 \cell -\pard\intbl\qc\fs16 01:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 12JAN2013 \cell +\pard\intbl\qc\fs16 03:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 06SEP2013 \cell -\pard\intbl\qc\fs16 12:00 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 15NOV2012 \cell +\pard\intbl\qc\fs16 05:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -273,143 +291,143 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 09FEB2014 \cell -\pard\intbl\qc\fs16 10:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs16 20MAR2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 29NOV2012 \cell +\pard\intbl\qc\fs16 19:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1180 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 12FEB2013 \cell -\pard\intbl\qc\fs16 02:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 24MAR2013 \cell +\pard\intbl\qc\fs16 06:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 26FEB2013 \cell -\pard\intbl\qc\fs16 04:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 11APR2013 \cell +\pard\intbl\qc\fs16 19:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1239 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 11JAN2014 \cell -\pard\intbl\qc\fs16 05:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 22MAY2014 \cell +\pard\intbl\qc\fs16 13:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 26JAN2014 \cell -\pard\intbl\qc\fs16 05:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 06JUN2014 \cell +\pard\intbl\qc\fs16 09:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 28JUN2014 \cell -\pard\intbl\qc\fs16 15:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs16 20MAR2014 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 07NOV2014 \cell +\pard\intbl\qc\fs16 07:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1275 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 07FEB2014 \cell -\pard\intbl\qc\fs16 00:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 02OCT2012 \cell +\pard\intbl\qc\fs16 03:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 23FEB2014 \cell -\pard\intbl\qc\fs16 02:00 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 17OCT2012 \cell +\pard\intbl\qc\fs16 18:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -417,17 +435,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1287 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 25JAN2014 \cell -\pard\intbl\qc\fs16 22:00 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 20MAR2013 \cell +\pard\intbl\qc\fs16 01:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell \row @@ -435,16 +453,16 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 12FEB2014 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 05JAN2013 \cell \pard\intbl\qc\fs16 22:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell @@ -453,53 +471,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 13JUL2014 \cell -\pard\intbl\qc\fs16 18:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 19JAN2013 \cell +\pard\intbl\qc\fs16 08:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1302 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 29AUG2013 \cell -\pard\intbl\qc\fs16 03:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 31JUL2013 \cell +\pard\intbl\qc\fs16 11:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 16SEP2013 \cell -\pard\intbl\qc\fs16 20:00 \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 19MAR2013 \cell +\pard\intbl\qc\fs16 14:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -507,89 +525,89 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1383 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 04FEB2013 \cell -\pard\intbl\qc\fs16 16:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs16 20MAR2014 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 03APR2013 \cell +\pard\intbl\qc\fs16 02:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 20FEB2013 \cell -\pard\intbl\qc\fs16 01:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 01-701-1442 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 26OCT2013 \cell +\pard\intbl\qc\fs16 09:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 31JUL2013 \cell -\pard\intbl\qc\fs16 07:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 10NOV2013 \cell +\pard\intbl\qc\fs16 05:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1444 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 05JAN2013 \cell -\pard\intbl\qc\fs16 09:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 18APR2014 \cell +\pard\intbl\qc\fs16 11:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 19JAN2013 \cell -\pard\intbl\qc\fs16 16:00 \cell +\pard\intbl\qc\fs16 01-702-1082 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 26JUL2013 \cell +\pard\intbl\qc\fs16 13:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -597,53 +615,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1076 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 25OCT2013 \cell -\pard\intbl\qc\fs16 16:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs16 20MAR2014 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 09AUG2013 \cell +\pard\intbl\qc\fs16 13:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 07NOV2013 \cell -\pard\intbl\qc\fs16 05:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 01-703-1086 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 02SEP2012 \cell +\pard\intbl\qc\fs16 08:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1258 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 20JUL2012 \cell -\pard\intbl\qc\fs16 05:00 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 17SEP2012 \cell +\pard\intbl\qc\fs16 10:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -651,17 +669,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 02AUG2012 \cell -\pard\intbl\qc\fs16 18:00 \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 20FEB2013 \cell +\pard\intbl\qc\fs16 17:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -669,35 +687,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 01JAN2013 \cell -\pard\intbl\qc\fs16 17:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 11MAR2013 \cell +\pard\intbl\qc\fs16 02:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1295 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 21NOV2013 \cell -\pard\intbl\qc\fs16 13:00 \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 17OCT2013 \cell +\pard\intbl\qc\fs16 06:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell \row @@ -705,35 +723,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 06DEC2013 \cell -\pard\intbl\qc\fs16 05:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 01NOV2013 \cell +\pard\intbl\qc\fs16 22:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1335 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 17MAR2014 \cell -\pard\intbl\qc\fs16 10:00 \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 16JUN2013 \cell +\pard\intbl\qc\fs16 07:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -741,17 +759,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 01APR2014 \cell -\pard\intbl\qc\fs16 16:00 \cell +\pard\intbl\qc\fs16 01-703-1279 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 13MAY2013 \cell +\pard\intbl\qc\fs16 00:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell \row @@ -759,17 +777,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1439 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 12MAR2014 \cell -\pard\intbl\qc\fs16 11:00 \cell +\pard\intbl\qc\fs16 01-703-1379 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 22SEP2013 \cell +\pard\intbl\qc\fs16 02:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell \row @@ -777,16 +795,16 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 27MAR2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 08OCT2013 \cell \pard\intbl\qc\fs16 12:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell @@ -795,35 +813,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 29AUG2014 \cell -\pard\intbl\qc\fs16 17:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1008 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 13JAN2013 \cell -\pard\intbl\qc\fs16 16:00 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 09MAR2014 \cell +\pard\intbl\qc\fs16 18:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell \pard\intbl\qc\fs16 20MAR2014 \cell \row @@ -831,35 +831,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 29JAN2013 \cell -\pard\intbl\qc\fs16 00:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs16 20MAR2014 \cell +\pard\intbl\qc\fs16 01-703-1403 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 12DEC2012 \cell +\pard\intbl\qc\fs16 15:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1017 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 06OCT2013 \cell -\pard\intbl\qc\fs16 00:00 \cell +\pard\intbl\qc\fs16 01-704-1009 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 27AUG2013 \cell +\pard\intbl\qc\fs16 16:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell \row @@ -867,53 +867,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 20OCT2013 \cell -\pard\intbl\qc\fs16 17:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15SEP2013 \cell +\pard\intbl\qc\fs16 22:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1065 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 24OCT2013 \cell -\pard\intbl\qc\fs16 21:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 27SEP2013 \cell +\pard\intbl\qc\fs16 11:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 08NOV2013 \cell -\pard\intbl\qc\fs16 01:00 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 12OCT2013 \cell +\pard\intbl\qc\fs16 08:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell \row @@ -921,17 +921,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1074 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 22JAN2014 \cell -\pard\intbl\qc\fs16 20:00 \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 23JAN2013 \cell +\pard\intbl\qc\fs16 16:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -939,35 +939,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 10FEB2014 \cell -\pard\intbl\qc\fs16 09:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs16 20MAR2014 \cell -\row -} - +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 04FEB2013 \cell +\pard\intbl\qc\fs16 20:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell +\row +} + { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1093 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 15MAR2013 \cell -\pard\intbl\qc\fs16 10:00 \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 02DEC2013 \cell +\pard\intbl\qc\fs16 05:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -975,17 +975,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 31MAR2013 \cell -\pard\intbl\qc\fs16 07:00 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 16DEC2013 \cell +\pard\intbl\qc\fs16 08:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -993,35 +993,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1241 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 25AUG2013 \cell -\pard\intbl\qc\fs16 19:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 01-704-1135 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 31OCT2013 \cell +\pard\intbl\qc\fs16 22:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 06SEP2013 \cell -\pard\intbl\qc\fs16 08:00 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15NOV2013 \cell +\pard\intbl\qc\fs16 20:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -1029,17 +1029,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1266 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 13OCT2013 \cell -\pard\intbl\qc\fs16 20:00 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 02MAY2014 \cell +\pard\intbl\qc\fs16 19:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell \pard\intbl\qc\fs16 20MAR2014 \cell \row @@ -1047,53 +1047,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 28OCT2013 \cell -\pard\intbl\qc\fs16 11:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1332 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 09DEC2013 \cell -\pard\intbl\qc\fs16 11:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 19NOV2012 \cell +\pard\intbl\qc\fs16 21:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 24DEC2013 \cell -\pard\intbl\qc\fs16 06:00 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 04DEC2012 \cell +\pard\intbl\qc\fs16 05:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell \row @@ -1101,17 +1083,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1280 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 17JAN2014 \cell -\pard\intbl\qc\fs16 01:00 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 14MAY2013 \cell +\pard\intbl\qc\fs16 14:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell \pard\intbl\qc\fs16 20MAR2014 \cell \row @@ -1119,17 +1101,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 01FEB2014 \cell -\pard\intbl\qc\fs16 22:00 \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 08JUL2013 \cell +\pard\intbl\qc\fs16 06:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell \pard\intbl\qc\fs16 20MAR2014 \cell \row @@ -1137,35 +1119,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 12JUL2014 \cell -\pard\intbl\qc\fs16 01:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 24JUL2013 \cell +\pard\intbl\qc\fs16 09:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1281 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 28NOV2013 \cell -\pard\intbl\qc\fs16 00:00 \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 23APR2014 \cell +\pard\intbl\qc\fs16 05:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -1173,35 +1155,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 16DEC2013 \cell -\pard\intbl\qc\fs16 07:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs16 20MAR2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 08MAY2014 \cell +\pard\intbl\qc\fs16 12:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1303 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 16DEC2013 \cell -\pard\intbl\qc\fs16 12:00 \cell +\pard\intbl\qc\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 27NOV2013 \cell +\pard\intbl\qc\fs16 23:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell \pard\intbl\qc\fs16 20MAR2014 \cell \row @@ -1209,17 +1191,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1310 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 02NOV2013 \cell -\pard\intbl\qc\fs16 13:00 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 19DEC2013 \cell +\pard\intbl\qc\fs16 17:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -1227,35 +1209,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 23NOV2013 \cell -\pard\intbl\qc\fs16 23:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1377 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 04JAN2014 \cell -\pard\intbl\qc\fs16 08:00 \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 16SEP2013 \cell +\pard\intbl\qc\fs16 09:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -1263,17 +1227,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-706-1049 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 14MAY2013 \cell -\pard\intbl\qc\fs16 01:00 \cell +\pard\intbl\qc\fs16 01-705-1292 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 14OCT2013 \cell +\pard\intbl\qc\fs16 22:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -1281,17 +1245,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 29MAY2013 \cell -\pard\intbl\qc\fs16 01:00 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 30OCT2013 \cell +\pard\intbl\qc\fs16 00:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell \pard\intbl\qc\fs16 20MAR2014 \cell \row @@ -1299,89 +1263,89 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1178 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 29DEC2013 \cell -\pard\intbl\qc\fs16 16:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 29APR2014 \cell +\pard\intbl\qc\fs16 18:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 19JAN2014 \cell -\pard\intbl\qc\fs16 23:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 01-705-1382 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 13MAY2013 \cell +\pard\intbl\qc\fs16 15:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1216 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 24OCT2012 \cell -\pard\intbl\qc\fs16 08:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 01-705-1393 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 07SEP2012 \cell +\pard\intbl\qc\fs16 07:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 09NOV2012 \cell -\pard\intbl\qc\fs16 05:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 28SEP2012 \cell +\pard\intbl\qc\fs16 13:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1336 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 07DEC2012 \cell -\pard\intbl\qc\fs16 03:00 \cell +\pard\intbl\qc\fs16 01-705-1431 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 23JUN2013 \cell +\pard\intbl\qc\fs16 15:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -1389,35 +1353,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 22DEC2012 \cell -\pard\intbl\qc\fs16 09:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 08JUL2013 \cell +\pard\intbl\qc\fs16 21:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 23MAY2013 \cell -\pard\intbl\qc\fs16 18:00 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 06DEC2013 \cell +\pard\intbl\qc\fs16 04:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -1425,53 +1389,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1347 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 20APR2013 \cell -\pard\intbl\qc\fs16 07:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 01-706-1384 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 15SEP2012 \cell +\pard\intbl\qc\fs16 13:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 05MAY2013 \cell -\pard\intbl\qc\fs16 19:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 20DEC2013 \cell +\pard\intbl\qc\fs16 08:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1406 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 26DEC2013 \cell -\pard\intbl\qc\fs16 15:00 \cell +\pard\intbl\qc\fs16 01-708-1019 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 20DEC2013 \cell +\pard\intbl\qc\fs16 00:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -1479,89 +1443,107 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 10JAN2014 \cell -\pard\intbl\qc\fs16 12:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 01-708-1032 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 09FEB2013 \cell +\pard\intbl\qc\fs16 22:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 17JUN2014 \cell -\pard\intbl\qc\fs16 11:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 24FEB2013 \cell +\pard\intbl\qc\fs16 19:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1029 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 25DEC2012 \cell +\pard\intbl\qc\fs16 01-708-1084 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 09MAY2013 \cell \pard\intbl\qc\fs16 05:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 10JAN2013 \cell -\pard\intbl\qc\fs16 04:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs16 15DEC2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 24MAY2013 \cell +\pard\intbl\qc\fs16 20:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 13JUN2013 \cell -\pard\intbl\qc\fs16 01:00 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 29OCT2013 \cell +\pard\intbl\qc\fs16 11:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1213 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 09FEB2013 \cell +\pard\intbl\qc\fs16 03:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell \pard\intbl\qc\fs16 05FEB2014 \cell \row @@ -1569,17 +1551,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1099 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 25OCT2013 \cell -\pard\intbl\qc\fs16 03:00 \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 21SEP2013 \cell +\pard\intbl\qc\fs16 14:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -1587,35 +1569,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 13NOV2013 \cell -\pard\intbl\qc\fs16 03:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs16 20MAR2014 \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 06FEB2013 \cell +\pard\intbl\qc\fs16 23:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 12APR2014 \cell -\pard\intbl\qc\fs16 09:00 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 22FEB2013 \cell +\pard\intbl\qc\fs16 01:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell \pard\intbl\qc\fs16 15DEC2013 \cell \row @@ -1623,125 +1605,125 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1168 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 02AUG2013 \cell -\pard\intbl\qc\fs16 13:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs16 05FEB2014 \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 25JAN2013 \cell +\pard\intbl\qc\fs16 11:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 18AUG2013 \cell -\pard\intbl\qc\fs16 03:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 09FEB2013 \cell +\pard\intbl\qc\fs16 00:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1238 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 15MAY2013 \cell -\pard\intbl\qc\fs16 05:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 01-708-1348 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 05AUG2013 \cell +\pard\intbl\qc\fs16 04:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-003 \cell +\pard\intbl\qc\fs16 05FEB2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 30MAY2013 \cell -\pard\intbl\qc\fs16 16:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 20AUG2013 \cell +\pard\intbl\qc\fs16 07:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1309 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 19JUN2013 \cell -\pard\intbl\qc\fs16 13:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 04FEB2014 \cell +\pard\intbl\qc\fs16 14:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 02JUL2013 \cell -\pard\intbl\qc\fs16 19:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 01-708-1353 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 04JUL2013 \cell +\pard\intbl\qc\fs16 13:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell +\pard\intbl\qc\fs16 20MAR2014 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 06DEC2013 \cell -\pard\intbl\qc\fs16 16:00 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 19JUL2013 \cell +\pard\intbl\qc\fs16 01:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell \pard\intbl\qc\fs16 10SEP2013 \cell \row @@ -1749,17 +1731,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1006 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 10FEB2013 \cell -\pard\intbl\qc\fs16 07:00 \cell +\pard\intbl\qc\fs16 01-708-1372 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 12APR2013 \cell +\pard\intbl\qc\fs16 03:00 \cell \pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell \pard\intbl\qc\fs16 20MAR2014 \cell \row @@ -1767,84 +1749,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 23FEB2013 \cell -\pard\intbl\qc\fs16 02:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 01-708-1428 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 09NOV2013 \cell +\pard\intbl\qc\fs16 23:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 28JUL2013 \cell -\pard\intbl\qc\fs16 05:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 24NOV2013 \cell +\pard\intbl\qc\fs16 12:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1021 \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 27SEP2013 \cell -\pard\intbl\qc\fs16 21:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs16 10SEP2013 \cell +\pard\intbl\qc\fs16 01-709-1007 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 31JUL2012 \cell +\pard\intbl\qc\fs16 19:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2214 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5244 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8468 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11595 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 12OCT2013 \cell -\pard\intbl\qc\fs16 15:00 \cell -\pard\intbl\qc\fs16 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs16 20MAR2014 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 19AUG2012 \cell +\pard\intbl\qc\fs16 19:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-002 \cell +\pard\intbl\qc\fs16 15DEC2013 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2924 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5803 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6579 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7630 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8681 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11651 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1020 \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 01DEC2012 \cell +\pard\intbl\qc\fs16 19:00 \cell +\pard\intbl\qc\fs16 XXX-YYY-ZZZ-004 \cell +\pard\intbl\qc\fs16 10SEP2013 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2214 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5244 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6255 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7361 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8468 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11595 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2924 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5803 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6579 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7630 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8681 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11651 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -1857,12 +1857,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2214 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5244 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6255 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7361 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8468 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11595 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2924 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5803 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6579 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7630 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8681 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11651 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/lsiex03/lsiex03.rtf b/tests/testthat/_snaps/lsiex03/lsiex03.rtf old mode 100755 new mode 100644 index 419c781e..00fa3454 --- a/tests/testthat/_snaps/lsiex03/lsiex03.rtf +++ b/tests/testthat/_snaps/lsiex03/lsiex03.rtf @@ -3,17 +3,21 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3254 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4100 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4546 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6195 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7309 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8423 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11587 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx754 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1220 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1830 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2440 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3086 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4270 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4916 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6064 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6889 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8073 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8970 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9508 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10333 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11230 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12127 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIEX03:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -26,2850 +30,21378 @@ \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx754 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx1220 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx1830 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2440 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3086 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4270 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4916 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6064 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6889 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8073 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8970 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9508 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10333 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11230 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12127 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr Prior to Infusion Start \cell +\pard\intbl\qc\fs16 \keepn\trhdr Prior to Infusion Start \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr During Infusion \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3254 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4100 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4546 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6195 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7309 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8423 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11587 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx754 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2440 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3086 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6064 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell \pard\intbl\qc\fs16 \keepn\trhdr Visit \cell \pard\intbl\qc\fs16 \keepn\trhdr Prescribed Dose Level (unit) \cell -\pard\intbl\qc\fs16 \keepn\trhdr Dose (unit) \cell -\pard\intbl\qc\fs16 \keepn\trhdr Total Volume Infused (unit) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Action Taken\super a\nosupersub / Reason \cell +\pard\intbl\qc\fs16 \keepn\trhdr Schedule Change New Dosing Frequency \cell +\pard\intbl\qc\fs16 \keepn\trhdr Dose Delayed? / Reason \cell +\pard\intbl\qc\fs16 \keepn\trhdr Total Dose to be Administered (unit) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Action Taken / Reason \cell +\pard\intbl\qc\fs16 \keepn\trhdr Total Volume of Investigational Product Infused (mL) \cell \pard\intbl\qc\fs16 \keepn\trhdr Infusion Rate (unit) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Actual Dose Administered (unit) \cell \pard\intbl\qc\fs16 \keepn\trhdr Start Date / Time (Study Day\super a\nosupersub ) \cell \pard\intbl\qc\fs16 \keepn\trhdr End Date / Time (Study Day\super a\nosupersub ) \cell -\pard\intbl\qc\fs16 \keepn\trhdr Action Taken / Reason Prior to Infusion \cell -\pard\intbl\qc\fs16 \keepn\trhdr Action Taken / Reason During Infusion \cell +\pard\intbl\qc\fs16 \keepn\trhdr Duration (hh:mm) \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 71 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 19JUL2013 / 03:00 (1) \cell -\pard\intbl\qc\fs16 01AUG2013 / --:-- (14) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Infusion rate increased / N/A \cell +\pard\intbl\qc\fs16 18MAR2014 / 15:00 (1) \cell +\pard\intbl\qc\fs16 31MAR2014 / 17:00 (14) \cell +\pard\intbl\qc\fs16 314:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1097 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 02AUG2013 / 10:00 (15) \cell -\pard\intbl\qc\fs16 06JAN2014 / --:-- (172) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01JAN2014 / 07:00 (1) \cell +\pard\intbl\qc\fs16 15JAN2014 / 22:00 (15) \cell +\pard\intbl\qc\fs16 351:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 300 mg \cell -\pard\intbl\qc\fs16 300 mg \cell -\pard\intbl\qc\fs16 300 mg \cell -\pard\intbl\qc\fs16 07JAN2014 / 11:00 (173) \cell -\pard\intbl\qc\fs16 14JAN2014 / --:-- (180) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 77 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 01JUL2014 / 17:00 (1) \cell -\pard\intbl\qc\fs16 15JUL2014 / --:-- (15) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16JAN2014 / 15:00 (16) \cell +\pard\intbl\qc\fs16 18JUN2014 / 13:00 (169) \cell +\pard\intbl\qc\fs16 3670:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 0 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 16JUL2014 / 10:00 (16) \cell -\pard\intbl\qc\fs16 17DEC2014 / --:-- (170) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event \cell -\pard\intbl\qc\fs16 Infusion interrupted / Adverse event \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JUN2014 / 18:00 (170) \cell +\pard\intbl\qc\fs16 09JUL2014 / 23:00 (190) \cell +\pard\intbl\qc\fs16 485:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 0 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 18DEC2014 / 07:00 (171) \cell -\pard\intbl\qc\fs16 30DEC2014 / --:-- (183) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event \cell -\pard\intbl\qc\fs16 / Adverse event \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Nausea, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07SEP2012 / 11:00 (1) \cell +\pard\intbl\qc\fs16 16SEP2012 / 22:00 (10) \cell +\pard\intbl\qc\fs16 227:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1133 \cell -\pard\intbl\qc\fs16 81 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 28OCT2012 / 08:00 (1) \cell -\pard\intbl\qc\fs16 12NOV2012 / --:-- (16) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 30NOV2012 / 17:00 (1) \cell +\pard\intbl\qc\fs16 13DEC2012 / 19:00 (14) \cell +\pard\intbl\qc\fs16 314:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 13NOV2012 / 08:00 (17) \cell -\pard\intbl\qc\fs16 18APR2013 / --:-- (173) \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14DEC2012 / 17:00 (15) \cell +\pard\intbl\qc\fs16 23JAN2013 / 17:00 (55) \cell +\pard\intbl\qc\fs16 960:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 19APR2013 / 00:00 (174) \cell -\pard\intbl\qc\fs16 28APR2013 / --:-- (183) \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 100 mg \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05DEC2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 09DEC2013 / 21:00 (5) \cell +\pard\intbl\qc\fs16 94:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1146 \cell -\pard\intbl\qc\fs16 75 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 20MAY2013 / 17:00 (1) \cell -\pard\intbl\qc\fs16 03JUN2013 / --:-- (15) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15FEB2013 / 10:00 (1) \cell +\pard\intbl\qc\fs16 02MAR2013 / 09:00 (16) \cell +\pard\intbl\qc\fs16 359:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 04JUN2013 / 05:00 (16) \cell -\pard\intbl\qc\fs16 26JUN2013 / --:-- (38) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03MAR2013 / 15:00 (17) \cell +\pard\intbl\qc\fs16 24MAR2013 / 20:00 (38) \cell +\pard\intbl\qc\fs16 509:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1148 \cell -\pard\intbl\qc\fs16 57 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 23AUG2013 / 01:00 (1) \cell -\pard\intbl\qc\fs16 05SEP2013 / --:-- (14) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 22JUL2012 / 00:00 (1) \cell +\pard\intbl\qc\fs16 07AUG2012 / 11:00 (17) \cell +\pard\intbl\qc\fs16 395:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 06SEP2013 / 12:00 (15) \cell -\pard\intbl\qc\fs16 08FEB2014 / --:-- (170) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell -\pard\intbl\qc\fs16 Infusion rate increased / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08AUG2012 / 10:00 (18) \cell +\pard\intbl\qc\fs16 11JAN2013 / 20:00 (174) \cell +\pard\intbl\qc\fs16 3754:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 0 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 60 mg \cell -\pard\intbl\qc\fs16 09FEB2014 / 10:00 (171) \cell -\pard\intbl\qc\fs16 20FEB2014 / --:-- (182) \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: ************ \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Sheet could not into the bladder \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12JAN2013 / 03:00 (175) \cell +\pard\intbl\qc\fs16 20JAN2013 / 17:00 (183) \cell +\pard\intbl\qc\fs16 206:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1180 \cell -\pard\intbl\qc\fs16 56 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 12FEB2013 / 02:00 (1) \cell -\pard\intbl\qc\fs16 25FEB2013 / --:-- (14) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 15NOV2012 / 05:00 (1) \cell +\pard\intbl\qc\fs16 28NOV2012 / 05:00 (14) \cell +\pard\intbl\qc\fs16 312:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 26FEB2013 / 04:00 (15) \cell -\pard\intbl\qc\fs16 18MAR2013 / --:-- (35) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29NOV2012 / 19:00 (15) \cell +\pard\intbl\qc\fs16 12JAN2013 / 11:00 (59) \cell +\pard\intbl\qc\fs16 1048:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1239 \cell -\pard\intbl\qc\fs16 56 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 67 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 11JAN2014 / 05:00 (1) \cell -\pard\intbl\qc\fs16 25JAN2014 / --:-- (15) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24MAR2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 10APR2013 / 23:00 (18) \cell +\pard\intbl\qc\fs16 425:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 26JAN2014 / 05:00 (16) \cell -\pard\intbl\qc\fs16 27JUN2014 / --:-- (168) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11APR2013 / 19:00 (19) \cell +\pard\intbl\qc\fs16 14JUN2013 / 06:00 (83) \cell +\pard\intbl\qc\fs16 1523:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 28JUN2014 / 15:00 (169) \cell -\pard\intbl\qc\fs16 10JUL2014 / --:-- (181) \cell -\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion interrupted / N/A \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22MAY2014 / 13:00 (1) \cell +\pard\intbl\qc\fs16 05JUN2014 / 07:00 (15) \cell +\pard\intbl\qc\fs16 330:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1275 \cell -\pard\intbl\qc\fs16 61 / Male / American Indian or Alaska Native \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Progression \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 07FEB2014 / 00:00 (1) \cell -\pard\intbl\qc\fs16 22FEB2014 / --:-- (16) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion rate increased / N/A \cell +\pard\intbl\qc\fs16 06JUN2014 / 09:00 (16) \cell +\pard\intbl\qc\fs16 06NOV2014 / 09:00 (169) \cell +\pard\intbl\qc\fs16 3672:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 23FEB2014 / 02:00 (17) \cell -\pard\intbl\qc\fs16 31MAY2014 / --:-- (114) \cell -\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07NOV2014 / 07:00 (170) \cell +\pard\intbl\qc\fs16 20NOV2014 / 23:00 (183) \cell +\pard\intbl\qc\fs16 328:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1287 \cell -\pard\intbl\qc\fs16 56 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Headache, Pyrexia) \cell +\pard\intbl\qc\fs16 7.5 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 25JAN2014 / 22:00 (1) \cell -\pard\intbl\qc\fs16 11FEB2014 / --:-- (18) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02OCT2012 / 03:00 (1) \cell +\pard\intbl\qc\fs16 16OCT2012 / 08:00 (15) \cell +\pard\intbl\qc\fs16 341:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 12FEB2014 / 22:00 (19) \cell -\pard\intbl\qc\fs16 12JUL2014 / --:-- (169) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17OCT2012 / 18:00 (16) \cell +\pard\intbl\qc\fs16 19MAR2013 / 06:00 (169) \cell +\pard\intbl\qc\fs16 3660:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 13JUL2014 / 18:00 (170) \cell -\pard\intbl\qc\fs16 26JUL2014 / --:-- (183) \cell -\pard\intbl\qc\fs16 Infusion skipped (and not made up) / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20MAR2013 / 01:00 (170) \cell +\pard\intbl\qc\fs16 02APR2013 / 03:00 (183) \cell +\pard\intbl\qc\fs16 314:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1302 \cell -\pard\intbl\qc\fs16 61 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 51 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 29AUG2013 / 03:00 (1) \cell -\pard\intbl\qc\fs16 15SEP2013 / --:-- (18) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05JAN2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 18JAN2013 / 09:00 (14) \cell +\pard\intbl\qc\fs16 299:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 16SEP2013 / 20:00 (19) \cell -\pard\intbl\qc\fs16 05NOV2013 / --:-- (69) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Infusion interrupted / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Tar-200 did not take the pretzel shape inside the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JAN2013 / 08:00 (15) \cell +\pard\intbl\qc\fs16 26JAN2013 / 00:00 (22) \cell +\pard\intbl\qc\fs16 160:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1383 \cell -\pard\intbl\qc\fs16 72 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 67 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 04FEB2013 / 16:00 (1) \cell -\pard\intbl\qc\fs16 19FEB2013 / --:-- (16) \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Rash, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31JUL2013 / 11:00 (1) \cell +\pard\intbl\qc\fs16 05AUG2013 / 11:00 (6) \cell +\pard\intbl\qc\fs16 120:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 100 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 20FEB2013 / 01:00 (17) \cell -\pard\intbl\qc\fs16 30JUL2013 / --:-- (177) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19MAR2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 02APR2013 / 11:00 (15) \cell +\pard\intbl\qc\fs16 333:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell \pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell \pard\intbl\qc\fs16 300 mg \cell -\pard\intbl\qc\fs16 300 mg \cell -\pard\intbl\qc\fs16 300 mg \cell -\pard\intbl\qc\fs16 31JUL2013 / 07:00 (178) \cell -\pard\intbl\qc\fs16 06AUG2013 / --:-- (184) \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03APR2013 / 02:00 (16) \cell +\pard\intbl\qc\fs16 30APR2013 / 16:00 (43) \cell +\pard\intbl\qc\fs16 662:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1444 \cell -\pard\intbl\qc\fs16 63 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-701-1442 \cell +\pard\intbl\qc\fs16 57 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 05JAN2013 / 09:00 (1) \cell -\pard\intbl\qc\fs16 18JAN2013 / --:-- (14) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Infusion interrupted / N/A \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26OCT2013 / 09:00 (1) \cell +\pard\intbl\qc\fs16 09NOV2013 / 18:00 (15) \cell +\pard\intbl\qc\fs16 345:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 19JAN2013 / 16:00 (15) \cell -\pard\intbl\qc\fs16 12FEB2013 / --:-- (39) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10NOV2013 / 05:00 (16) \cell +\pard\intbl\qc\fs16 17APR2014 / 15:00 (174) \cell +\pard\intbl\qc\fs16 3802:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1076 \cell -\pard\intbl\qc\fs16 69 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 25OCT2013 / 16:00 (1) \cell -\pard\intbl\qc\fs16 06NOV2013 / --:-- (13) \cell -\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / N/A \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Fatigue, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 18APR2014 / 11:00 (175) \cell +\pard\intbl\qc\fs16 26APR2014 / 06:00 (183) \cell +\pard\intbl\qc\fs16 187:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-702-1082 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 07NOV2013 / 05:00 (14) \cell -\pard\intbl\qc\fs16 24DEC2013 / --:-- (61) \cell -\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26JUL2013 / 13:00 (1) \cell +\pard\intbl\qc\fs16 08AUG2013 / 19:00 (14) \cell +\pard\intbl\qc\fs16 318:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1258 \cell -\pard\intbl\qc\fs16 78 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 20JUL2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 01AUG2012 / --:-- (13) \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09AUG2013 / 13:00 (15) \cell +\pard\intbl\qc\fs16 13OCT2013 / 01:00 (80) \cell +\pard\intbl\qc\fs16 1548:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1086 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 02AUG2012 / 18:00 (14) \cell -\pard\intbl\qc\fs16 31DEC2012 / --:-- (165) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02SEP2012 / 08:00 (1) \cell +\pard\intbl\qc\fs16 16SEP2012 / 13:00 (15) \cell +\pard\intbl\qc\fs16 341:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 01JAN2013 / 17:00 (166) \cell -\pard\intbl\qc\fs16 11JAN2013 / --:-- (176) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17SEP2012 / 10:00 (16) \cell +\pard\intbl\qc\fs16 04DEC2012 / 23:00 (94) \cell +\pard\intbl\qc\fs16 1885:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1295 \cell -\pard\intbl\qc\fs16 88 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 21NOV2013 / 13:00 (1) \cell -\pard\intbl\qc\fs16 05DEC2013 / --:-- (15) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 20FEB2013 / 17:00 (1) \cell +\pard\intbl\qc\fs16 10MAR2013 / 06:00 (19) \cell +\pard\intbl\qc\fs16 421:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 06DEC2013 / 05:00 (16) \cell -\pard\intbl\qc\fs16 19APR2014 / --:-- (150) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion rate increased / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11MAR2013 / 02:00 (20) \cell +\pard\intbl\qc\fs16 13JUN2013 / 17:00 (114) \cell +\pard\intbl\qc\fs16 2271:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1335 \cell -\pard\intbl\qc\fs16 67 / Female / Black or African American \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 17MAR2014 / 10:00 (1) \cell -\pard\intbl\qc\fs16 31MAR2014 / --:-- (15) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Infusion rate increased / N/A \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17OCT2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 31OCT2013 / 21:00 (15) \cell +\pard\intbl\qc\fs16 351:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 01APR2014 / 16:00 (16) \cell -\pard\intbl\qc\fs16 07MAY2014 / --:-- (52) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01NOV2013 / 22:00 (16) \cell +\pard\intbl\qc\fs16 11DEC2013 / 00:00 (56) \cell +\pard\intbl\qc\fs16 938:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-703-1439 \cell -\pard\intbl\qc\fs16 76 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 76 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 12MAR2014 / 11:00 (1) \cell -\pard\intbl\qc\fs16 26MAR2014 / --:-- (15) \cell -\pard\intbl\qc\fs16 Infusion skipped (and not made up) / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16JUN2013 / 07:00 (1) \cell +\pard\intbl\qc\fs16 29JUN2013 / 00:00 (14) \cell +\pard\intbl\qc\fs16 305:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1279 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 27MAR2014 / 12:00 (16) \cell -\pard\intbl\qc\fs16 28AUG2014 / --:-- (170) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13MAY2013 / 00:00 (1) \cell +\pard\intbl\qc\fs16 03JUN2013 / 02:00 (22) \cell +\pard\intbl\qc\fs16 506:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1379 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 29AUG2014 / 17:00 (171) \cell -\pard\intbl\qc\fs16 11SEP2014 / --:-- (184) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 22SEP2013 / 02:00 (1) \cell +\pard\intbl\qc\fs16 07OCT2013 / 16:00 (16) \cell +\pard\intbl\qc\fs16 374:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1008 \cell -\pard\intbl\qc\fs16 76 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 13JAN2013 / 16:00 (1) \cell -\pard\intbl\qc\fs16 28JAN2013 / --:-- (16) \cell -\pard\intbl\qc\fs16 Infusion skipped (and not made up) / N/A \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Suspicion of disease progression \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08OCT2013 / 12:00 (17) \cell +\pard\intbl\qc\fs16 08MAR2014 / 22:00 (168) \cell +\pard\intbl\qc\fs16 3634:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 29JAN2013 / 00:00 (17) \cell -\pard\intbl\qc\fs16 21FEB2013 / --:-- (40) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09MAR2014 / 18:00 (169) \cell +\pard\intbl\qc\fs16 21MAR2014 / 12:00 (181) \cell +\pard\intbl\qc\fs16 282:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1017 \cell -\pard\intbl\qc\fs16 77 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-703-1403 \cell +\pard\intbl\qc\fs16 67 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 06OCT2013 / 00:00 (1) \cell -\pard\intbl\qc\fs16 19OCT2013 / --:-- (14) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12DEC2012 / 15:00 (1) \cell +\pard\intbl\qc\fs16 13DEC2012 / 11:00 (2) \cell +\pard\intbl\qc\fs16 20:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1009 \cell +\pard\intbl\qc\fs16 83 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 20OCT2013 / 17:00 (15) \cell -\pard\intbl\qc\fs16 18NOV2013 / --:-- (44) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27AUG2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 14SEP2013 / 04:00 (19) \cell +\pard\intbl\qc\fs16 420:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1065 \cell -\pard\intbl\qc\fs16 75 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 24OCT2013 / 21:00 (1) \cell -\pard\intbl\qc\fs16 07NOV2013 / --:-- (15) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 08NOV2013 / 01:00 (16) \cell -\pard\intbl\qc\fs16 22DEC2013 / --:-- (60) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15SEP2013 / 22:00 (20) \cell +\pard\intbl\qc\fs16 25SEP2013 / 20:00 (30) \cell +\pard\intbl\qc\fs16 238:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1074 \cell -\pard\intbl\qc\fs16 80 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 22JAN2014 / 20:00 (1) \cell -\pard\intbl\qc\fs16 09FEB2014 / --:-- (19) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27SEP2013 / 11:00 (1) \cell +\pard\intbl\qc\fs16 11OCT2013 / 23:00 (15) \cell +\pard\intbl\qc\fs16 348:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 10FEB2014 / 09:00 (20) \cell -\pard\intbl\qc\fs16 20MAR2014 / --:-- (58) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Infusion rate increased / N/A \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12OCT2013 / 08:00 (16) \cell +\pard\intbl\qc\fs16 24OCT2013 / 03:00 (28) \cell +\pard\intbl\qc\fs16 283:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1093 \cell -\pard\intbl\qc\fs16 79 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 15MAR2013 / 10:00 (1) \cell -\pard\intbl\qc\fs16 30MAR2013 / --:-- (16) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23JAN2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 03FEB2013 / 21:00 (12) \cell +\pard\intbl\qc\fs16 269:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 31MAR2013 / 07:00 (17) \cell -\pard\intbl\qc\fs16 17JUN2013 / --:-- (95) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Infusion interrupted / N/A \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04FEB2013 / 20:00 (13) \cell +\pard\intbl\qc\fs16 07JUL2013 / 20:00 (166) \cell +\pard\intbl\qc\fs16 3672:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1241 \cell -\pard\intbl\qc\fs16 86 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 25AUG2013 / 19:00 (1) \cell -\pard\intbl\qc\fs16 05SEP2013 / --:-- (12) \cell -\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 02DEC2013 / 05:00 (1) \cell +\pard\intbl\qc\fs16 15DEC2013 / 16:00 (14) \cell +\pard\intbl\qc\fs16 323:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 06SEP2013 / 08:00 (13) \cell -\pard\intbl\qc\fs16 09OCT2013 / --:-- (46) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16DEC2013 / 08:00 (15) \cell +\pard\intbl\qc\fs16 01FEB2014 / 19:00 (62) \cell +\pard\intbl\qc\fs16 1139:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1266 \cell -\pard\intbl\qc\fs16 82 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-704-1135 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 13OCT2013 / 20:00 (1) \cell -\pard\intbl\qc\fs16 27OCT2013 / --:-- (15) \cell -\pard\intbl\qc\fs16 Infusion skipped (and not made up) / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 31OCT2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 14NOV2013 / 14:00 (15) \cell +\pard\intbl\qc\fs16 328:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 28OCT2013 / 11:00 (16) \cell -\pard\intbl\qc\fs16 06DEC2013 / --:-- (55) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15NOV2013 / 20:00 (16) \cell +\pard\intbl\qc\fs16 01MAY2014 / 16:00 (183) \cell +\pard\intbl\qc\fs16 4004:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-704-1332 \cell -\pard\intbl\qc\fs16 80 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 09DEC2013 / 11:00 (1) \cell -\pard\intbl\qc\fs16 23DEC2013 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02MAY2014 / 19:00 (184) \cell +\pard\intbl\qc\fs16 16MAY2014 / 08:00 (198) \cell +\pard\intbl\qc\fs16 325:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19NOV2012 / 21:00 (1) \cell +\pard\intbl\qc\fs16 03DEC2012 / 21:00 (15) \cell +\pard\intbl\qc\fs16 336:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 24DEC2013 / 06:00 (16) \cell -\pard\intbl\qc\fs16 14FEB2014 / --:-- (68) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04DEC2012 / 05:00 (16) \cell +\pard\intbl\qc\fs16 13MAY2013 / 00:00 (176) \cell +\pard\intbl\qc\fs16 3835:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1280 \cell -\pard\intbl\qc\fs16 56 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 17JAN2014 / 01:00 (1) \cell -\pard\intbl\qc\fs16 31JAN2014 / --:-- (15) \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14MAY2013 / 14:00 (177) \cell +\pard\intbl\qc\fs16 27MAY2013 / 06:00 (190) \cell +\pard\intbl\qc\fs16 304:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 68 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 01FEB2014 / 22:00 (16) \cell -\pard\intbl\qc\fs16 11JUL2014 / --:-- (176) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion interrupted / N/A \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08JUL2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 23JUL2013 / 13:00 (16) \cell +\pard\intbl\qc\fs16 367:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 12JUL2014 / 01:00 (177) \cell -\pard\intbl\qc\fs16 25JUL2014 / --:-- (190) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24JUL2013 / 09:00 (17) \cell +\pard\intbl\qc\fs16 05AUG2013 / 06:00 (29) \cell +\pard\intbl\qc\fs16 285:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1281 \cell -\pard\intbl\qc\fs16 73 / Female / Black or African American \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 28NOV2013 / 00:00 (1) \cell -\pard\intbl\qc\fs16 15DEC2013 / --:-- (18) \cell -\pard\intbl\qc\fs16 Infusion skipped (and not made up) / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23APR2014 / 05:00 (1) \cell +\pard\intbl\qc\fs16 07MAY2014 / 14:00 (15) \cell +\pard\intbl\qc\fs16 345:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 16DEC2013 / 07:00 (19) \cell -\pard\intbl\qc\fs16 27FEB2014 / --:-- (92) \cell -\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08MAY2014 / 12:00 (16) \cell +\pard\intbl\qc\fs16 04JUL2014 / 16:00 (73) \cell +\pard\intbl\qc\fs16 1372:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1303 \cell -\pard\intbl\qc\fs16 72 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 16DEC2013 / 12:00 (1) \cell -\pard\intbl\qc\fs16 30DEC2013 / --:-- (15) \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 Dose re-escalated / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27NOV2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 18DEC2013 / 12:00 (22) \cell +\pard\intbl\qc\fs16 493:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 31DEC2013 / 22:00 (16) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19DEC2013 / 17:00 (23) \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 NA:NA \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1310 \cell -\pard\intbl\qc\fs16 74 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 87 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Pqc \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 02NOV2013 / 13:00 (1) \cell -\pard\intbl\qc\fs16 22NOV2013 / --:-- (21) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion interrupted / N/A \cell +\pard\intbl\qc\fs16 16SEP2013 / 09:00 (1) \cell +\pard\intbl\qc\fs16 28SEP2013 / 02:00 (13) \cell +\pard\intbl\qc\fs16 281:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 23NOV2013 / 23:00 (22) \cell -\pard\intbl\qc\fs16 23JAN2014 / --:-- (83) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Infusion rate increased / N/A \cell +\pard\intbl\qc\fs16 01-705-1292 \cell +\pard\intbl\qc\fs16 60 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14OCT2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 29OCT2013 / 23:00 (16) \cell +\pard\intbl\qc\fs16 361:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-705-1377 \cell -\pard\intbl\qc\fs16 63 / Female / Black or African American \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 04JAN2014 / 08:00 (1) \cell -\pard\intbl\qc\fs16 25JAN2014 / --:-- (22) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion interrupted / N/A \cell +\pard\intbl\qc\fs16 30OCT2013 / 00:00 (17) \cell +\pard\intbl\qc\fs16 28APR2014 / 23:00 (197) \cell +\pard\intbl\qc\fs16 4343:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 26JAN2014 / 21:00 (23) \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / N/A \cell -\pard\intbl\qc\fs16 Infusion interrupted / N/A \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29APR2014 / 18:00 (198) \cell +\pard\intbl\qc\fs16 13MAY2014 / 23:00 (212) \cell +\pard\intbl\qc\fs16 341:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-706-1049 \cell -\pard\intbl\qc\fs16 60 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-705-1382 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Bladder mapping performed on 20 nov 2023 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 14MAY2013 / 01:00 (1) \cell -\pard\intbl\qc\fs16 28MAY2013 / --:-- (15) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell +\pard\intbl\qc\fs16 13MAY2013 / 15:00 (1) \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 NA:NA \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1393 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 200 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 29MAY2013 / 01:00 (16) \cell -\pard\intbl\qc\fs16 18JUN2013 / --:-- (36) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07SEP2012 / 07:00 (1) \cell +\pard\intbl\qc\fs16 27SEP2012 / 07:00 (21) \cell +\pard\intbl\qc\fs16 480:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1178 \cell -\pard\intbl\qc\fs16 77 / Female / Black or African American \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 29DEC2013 / 16:00 (1) \cell -\pard\intbl\qc\fs16 18JAN2014 / --:-- (21) \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28SEP2012 / 13:00 (22) \cell +\pard\intbl\qc\fs16 01FEB2013 / 15:00 (148) \cell +\pard\intbl\qc\fs16 3026:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1431 \cell +\pard\intbl\qc\fs16 68 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 19JAN2014 / 23:00 (22) \cell -\pard\intbl\qc\fs16 06APR2014 / --:-- (99) \cell -\pard\intbl\qc\fs16 Infusion skipped (and not made up) / N/A \cell -\pard\intbl\qc\fs16 Infusion interrupted / N/A \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23JUN2013 / 15:00 (1) \cell +\pard\intbl\qc\fs16 07JUL2013 / 03:00 (15) \cell +\pard\intbl\qc\fs16 324:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1216 \cell -\pard\intbl\qc\fs16 78 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 24OCT2012 / 08:00 (1) \cell -\pard\intbl\qc\fs16 08NOV2012 / --:-- (16) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 08JUL2013 / 21:00 (16) \cell +\pard\intbl\qc\fs16 05DEC2013 / 01:00 (166) \cell +\pard\intbl\qc\fs16 3580:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 09NOV2012 / 05:00 (17) \cell -\pard\intbl\qc\fs16 29NOV2012 / --:-- (37) \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / N/A \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06DEC2013 / 04:00 (167) \cell +\pard\intbl\qc\fs16 19DEC2013 / 17:00 (180) \cell +\pard\intbl\qc\fs16 325:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1336 \cell -\pard\intbl\qc\fs16 73 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-706-1384 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 07DEC2012 / 03:00 (1) \cell -\pard\intbl\qc\fs16 21DEC2012 / --:-- (15) \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / N/A \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15SEP2012 / 13:00 (1) \cell +\pard\intbl\qc\fs16 24SEP2012 / 14:00 (10) \cell +\pard\intbl\qc\fs16 217:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 200 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 22DEC2012 / 09:00 (16) \cell -\pard\intbl\qc\fs16 22MAY2013 / --:-- (167) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20DEC2013 / 08:00 (1) \cell +\pard\intbl\qc\fs16 24DEC2013 / 20:00 (5) \cell +\pard\intbl\qc\fs16 108:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 01-708-1019 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 23MAY2013 / 18:00 (168) \cell -\pard\intbl\qc\fs16 05JUN2013 / --:-- (181) \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 100 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20DEC2013 / 00:00 (1) \cell +\pard\intbl\qc\fs16 01JAN2014 / 05:00 (13) \cell +\pard\intbl\qc\fs16 293:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1347 \cell -\pard\intbl\qc\fs16 61 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-708-1032 \cell +\pard\intbl\qc\fs16 62 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 20APR2013 / 07:00 (1) \cell -\pard\intbl\qc\fs16 04MAY2013 / --:-- (15) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09FEB2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 23FEB2013 / 22:00 (15) \cell +\pard\intbl\qc\fs16 336:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 05MAY2013 / 19:00 (16) \cell -\pard\intbl\qc\fs16 18JUN2013 / --:-- (60) \cell -\pard\intbl\qc\fs16 Same dose as prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24FEB2013 / 19:00 (16) \cell +\pard\intbl\qc\fs16 01MAR2013 / 09:00 (21) \cell +\pard\intbl\qc\fs16 110:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-708-1406 \cell -\pard\intbl\qc\fs16 71 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-708-1084 \cell +\pard\intbl\qc\fs16 73 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 26DEC2013 / 15:00 (1) \cell -\pard\intbl\qc\fs16 09JAN2014 / --:-- (15) \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 09MAY2013 / 05:00 (1) \cell +\pard\intbl\qc\fs16 23MAY2013 / 12:00 (15) \cell +\pard\intbl\qc\fs16 343:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 10JAN2014 / 12:00 (16) \cell -\pard\intbl\qc\fs16 16JUN2014 / --:-- (173) \cell -\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24MAY2013 / 20:00 (16) \cell +\pard\intbl\qc\fs16 28OCT2013 / 15:00 (173) \cell +\pard\intbl\qc\fs16 3763:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 17JUN2014 / 11:00 (174) \cell -\pard\intbl\qc\fs16 02JUL2014 / --:-- (189) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: The dose delayed due to turb performed 10-nov-2023 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29OCT2013 / 11:00 (174) \cell +\pard\intbl\qc\fs16 11NOV2013 / 02:00 (187) \cell +\pard\intbl\qc\fs16 303:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1029 \cell -\pard\intbl\qc\fs16 82 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-708-1213 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 25DEC2012 / 05:00 (1) \cell -\pard\intbl\qc\fs16 09JAN2013 / --:-- (16) \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09FEB2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 22FEB2013 / 03:00 (14) \cell +\pard\intbl\qc\fs16 312:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 10JAN2013 / 04:00 (17) \cell -\pard\intbl\qc\fs16 12JUN2013 / --:-- (170) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 21SEP2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 21SEP2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 -8:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 13JUN2013 / 01:00 (171) \cell -\pard\intbl\qc\fs16 26JUN2013 / --:-- (184) \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / N/A \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06FEB2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 21FEB2013 / 17:00 (16) \cell +\pard\intbl\qc\fs16 354:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1099 \cell -\pard\intbl\qc\fs16 79 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 25OCT2013 / 03:00 (1) \cell -\pard\intbl\qc\fs16 12NOV2013 / --:-- (19) \cell -\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22FEB2013 / 01:00 (17) \cell +\pard\intbl\qc\fs16 22MAR2013 / 13:00 (45) \cell +\pard\intbl\qc\fs16 684:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 61 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 150 mg \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 13NOV2013 / 03:00 (20) \cell -\pard\intbl\qc\fs16 11APR2014 / --:-- (169) \cell -\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Infusion rate increased / N/A \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25JAN2013 / 11:00 (1) \cell +\pard\intbl\qc\fs16 08FEB2013 / 23:00 (15) \cell +\pard\intbl\qc\fs16 348:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 12APR2014 / 09:00 (170) \cell -\pard\intbl\qc\fs16 25APR2014 / --:-- (183) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09FEB2013 / 00:00 (16) \cell +\pard\intbl\qc\fs16 03MAY2013 / 19:00 (99) \cell +\pard\intbl\qc\fs16 2011:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1168 \cell -\pard\intbl\qc\fs16 72 / Female / White \cell -\pard\intbl\qc\fs16 BASELINE \cell +\pard\intbl\qc\fs16 01-708-1348 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell \pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 02AUG2013 / 13:00 (1) \cell -\pard\intbl\qc\fs16 17AUG2013 / --:-- (16) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05AUG2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 19AUG2013 / 11:00 (15) \cell +\pard\intbl\qc\fs16 343:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20AUG2013 / 07:00 (16) \cell +\pard\intbl\qc\fs16 03FEB2014 / 22:00 (183) \cell +\pard\intbl\qc\fs16 4023:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04FEB2014 / 14:00 (184) \cell +\pard\intbl\qc\fs16 13FEB2014 / 14:00 (193) \cell +\pard\intbl\qc\fs16 216:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1353 \cell +\pard\intbl\qc\fs16 87 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04JUL2013 / 13:00 (1) \cell +\pard\intbl\qc\fs16 18JUL2013 / 00:00 (15) \cell +\pard\intbl\qc\fs16 323:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JUL2013 / 01:00 (16) \cell +\pard\intbl\qc\fs16 28AUG2013 / 11:00 (56) \cell +\pard\intbl\qc\fs16 970:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1372 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12APR2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 19APR2013 / 07:00 (8) \cell +\pard\intbl\qc\fs16 172:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1428 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Rash, Pyrexia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09NOV2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 23NOV2013 / 09:00 (15) \cell +\pard\intbl\qc\fs16 322:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24NOV2013 / 12:00 (16) \cell +\pard\intbl\qc\fs16 14DEC2013 / 19:00 (36) \cell +\pard\intbl\qc\fs16 487:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1007 \cell +\pard\intbl\qc\fs16 54 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31JUL2012 / 19:00 (1) \cell +\pard\intbl\qc\fs16 18AUG2012 / 18:00 (19) \cell +\pard\intbl\qc\fs16 431:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19AUG2012 / 19:00 (20) \cell +\pard\intbl\qc\fs16 28AUG2012 / 06:00 (29) \cell +\pard\intbl\qc\fs16 203:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1020 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01DEC2012 / 19:00 (1) \cell +\pard\intbl\qc\fs16 15DEC2012 / 11:00 (15) \cell +\pard\intbl\qc\fs16 328:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16DEC2012 / 21:00 (16) \cell +\pard\intbl\qc\fs16 18MAY2013 / 14:00 (169) \cell +\pard\intbl\qc\fs16 3665:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19MAY2013 / 21:00 (170) \cell +\pard\intbl\qc\fs16 01JUN2013 / 03:00 (183) \cell +\pard\intbl\qc\fs16 294:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1081 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Urine culture not disponible \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 18JAN2014 / 02:00 (1) \cell +\pard\intbl\qc\fs16 01FEB2014 / 08:00 (15) \cell +\pard\intbl\qc\fs16 342:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02FEB2014 / 05:00 (16) \cell +\pard\intbl\qc\fs16 27APR2014 / 20:00 (100) \cell +\pard\intbl\qc\fs16 2031:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1102 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15JAN2013 / 21:00 (1) \cell +\pard\intbl\qc\fs16 31JAN2013 / 05:00 (17) \cell +\pard\intbl\qc\fs16 368:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01FEB2013 / 17:00 (18) \cell +\pard\intbl\qc\fs16 27MAR2013 / 16:00 (72) \cell +\pard\intbl\qc\fs16 1295:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04MAR2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 19MAR2013 / 21:00 (16) \cell +\pard\intbl\qc\fs16 377:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20MAR2013 / 16:00 (17) \cell +\pard\intbl\qc\fs16 11JUN2013 / 22:00 (100) \cell +\pard\intbl\qc\fs16 1998:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1285 \cell +\pard\intbl\qc\fs16 87 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24MAR2013 / 01:00 (1) \cell +\pard\intbl\qc\fs16 08APR2013 / 07:00 (16) \cell +\pard\intbl\qc\fs16 366:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Vomiting, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09APR2013 / 03:00 (17) \cell +\pard\intbl\qc\fs16 23MAY2013 / 07:00 (61) \cell +\pard\intbl\qc\fs16 1060:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1326 \cell +\pard\intbl\qc\fs16 75 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05APR2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 18APR2013 / 04:00 (14) \cell +\pard\intbl\qc\fs16 300:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19APR2013 / 21:00 (15) \cell +\pard\intbl\qc\fs16 20SEP2013 / 16:00 (169) \cell +\pard\intbl\qc\fs16 3691:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 21SEP2013 / 00:00 (170) \cell +\pard\intbl\qc\fs16 02OCT2013 / 21:00 (181) \cell +\pard\intbl\qc\fs16 285:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1329 \cell +\pard\intbl\qc\fs16 70 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15AUG2013 / 13:00 (1) \cell +\pard\intbl\qc\fs16 25AUG2013 / 05:00 (11) \cell +\pard\intbl\qc\fs16 232:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1424 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03MAR2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 07MAR2013 / 13:00 (5) \cell +\pard\intbl\qc\fs16 95:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1002 \cell +\pard\intbl\qc\fs16 88 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14JAN2014 / 18:00 (1) \cell +\pard\intbl\qc\fs16 18JAN2014 / 14:00 (5) \cell +\pard\intbl\qc\fs16 92:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1045 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03JUN2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 17JUN2013 / 15:00 (15) \cell +\pard\intbl\qc\fs16 337:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 18JUN2013 / 22:00 (16) \cell +\pard\intbl\qc\fs16 13AUG2013 / 01:00 (72) \cell +\pard\intbl\qc\fs16 1323:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1053 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26DEC2012 / 16:00 (1) \cell +\pard\intbl\qc\fs16 09JAN2013 / 09:00 (15) \cell +\pard\intbl\qc\fs16 329:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10JAN2013 / 10:00 (16) \cell +\pard\intbl\qc\fs16 10FEB2013 / 18:00 (47) \cell +\pard\intbl\qc\fs16 752:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1154 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29MAR2014 / 04:00 (1) \cell +\pard\intbl\qc\fs16 12APR2014 / 21:00 (15) \cell +\pard\intbl\qc\fs16 353:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13APR2014 / 21:00 (16) \cell +\pard\intbl\qc\fs16 27APR2014 / 01:00 (30) \cell +\pard\intbl\qc\fs16 316:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1166 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 30NOV2012 / 15:00 (1) \cell +\pard\intbl\qc\fs16 14DEC2012 / 21:00 (15) \cell +\pard\intbl\qc\fs16 342:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Drug was never administered because the subject dropped out prior to first dose \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15DEC2012 / 22:00 (16) \cell +\pard\intbl\qc\fs16 19MAR2013 / 20:00 (110) \cell +\pard\intbl\qc\fs16 2254:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1235 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26SEP2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 10OCT2012 / 23:00 (15) \cell +\pard\intbl\qc\fs16 353:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11OCT2012 / 18:00 (16) \cell +\pard\intbl\qc\fs16 13MAR2013 / 10:00 (169) \cell +\pard\intbl\qc\fs16 3664:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14MAR2013 / 12:00 (170) \cell +\pard\intbl\qc\fs16 27MAR2013 / 03:00 (183) \cell +\pard\intbl\qc\fs16 303:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1270 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12FEB2014 / 18:00 (1) \cell +\pard\intbl\qc\fs16 01MAR2014 / 13:00 (18) \cell +\pard\intbl\qc\fs16 403:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1300 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15DEC2012 / 01:00 (1) \cell +\pard\intbl\qc\fs16 30DEC2012 / 19:00 (16) \cell +\pard\intbl\qc\fs16 378:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Due to personal schedule \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31DEC2012 / 00:00 (17) \cell +\pard\intbl\qc\fs16 15FEB2013 / 01:00 (63) \cell +\pard\intbl\qc\fs16 1105:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1358 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17SEP2012 / 05:00 (1) \cell +\pard\intbl\qc\fs16 01OCT2012 / 03:00 (15) \cell +\pard\intbl\qc\fs16 334:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02OCT2012 / 19:00 (16) \cell +\pard\intbl\qc\fs16 09FEB2013 / 17:00 (146) \cell +\pard\intbl\qc\fs16 3118:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1385 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29OCT2012 / 09:00 (1) \cell +\pard\intbl\qc\fs16 12NOV2012 / 17:00 (15) \cell +\pard\intbl\qc\fs16 344:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13NOV2012 / 16:00 (16) \cell +\pard\intbl\qc\fs16 18FEB2013 / 04:00 (113) \cell +\pard\intbl\qc\fs16 2316:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-711-1143 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03APR2013 / 00:00 (1) \cell +\pard\intbl\qc\fs16 17APR2013 / 14:00 (15) \cell +\pard\intbl\qc\fs16 350:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 18APR2013 / 02:00 (16) \cell +\pard\intbl\qc\fs16 30MAY2013 / 14:00 (58) \cell +\pard\intbl\qc\fs16 1020:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-711-1433 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27JAN2013 / 15:00 (1) \cell +\pard\intbl\qc\fs16 05FEB2013 / 20:00 (10) \cell +\pard\intbl\qc\fs16 221:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1043 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15SEP2013 / 09:00 (1) \cell +\pard\intbl\qc\fs16 30SEP2013 / 02:00 (16) \cell +\pard\intbl\qc\fs16 353:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Suspicion of disease progression \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01OCT2013 / 03:00 (17) \cell +\pard\intbl\qc\fs16 28FEB2014 / 13:00 (167) \cell +\pard\intbl\qc\fs16 3610:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01MAR2014 / 20:00 (168) \cell +\pard\intbl\qc\fs16 24MAR2014 / 02:00 (191) \cell +\pard\intbl\qc\fs16 534:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1073 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache, Oedema peripheral) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 30MAR2014 / 07:00 (1) \cell +\pard\intbl\qc\fs16 14APR2014 / 02:00 (16) \cell +\pard\intbl\qc\fs16 355:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15APR2014 / 16:00 (17) \cell +\pard\intbl\qc\fs16 21SEP2014 / 05:00 (176) \cell +\pard\intbl\qc\fs16 3805:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Due to personal schedule \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22SEP2014 / 15:00 (177) \cell +\pard\intbl\qc\fs16 05OCT2014 / 04:00 (190) \cell +\pard\intbl\qc\fs16 301:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1448 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JAN2014 / 13:00 (1) \cell +\pard\intbl\qc\fs16 01FEB2014 / 02:00 (14) \cell +\pard\intbl\qc\fs16 301:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02FEB2014 / 08:00 (15) \cell +\pard\intbl\qc\fs16 16MAY2014 / 07:00 (118) \cell +\pard\intbl\qc\fs16 2471:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1068 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08AUG2013 / 10:00 (1) \cell +\pard\intbl\qc\fs16 22AUG2013 / 03:00 (15) \cell +\pard\intbl\qc\fs16 329:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23AUG2013 / 04:00 (16) \cell +\pard\intbl\qc\fs16 08OCT2013 / 20:00 (62) \cell +\pard\intbl\qc\fs16 1120:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1195 \cell +\pard\intbl\qc\fs16 75 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26APR2013 / 18:00 (1) \cell +\pard\intbl\qc\fs16 09MAY2013 / 21:00 (14) \cell +\pard\intbl\qc\fs16 315:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10MAY2013 / 13:00 (15) \cell +\pard\intbl\qc\fs16 10OCT2013 / 21:00 (168) \cell +\pard\intbl\qc\fs16 3680:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11OCT2013 / 23:00 (169) \cell +\pard\intbl\qc\fs16 23OCT2013 / 11:00 (181) \cell +\pard\intbl\qc\fs16 276:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1425 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15AUG2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 19AUG2013 / 12:00 (5) \cell +\pard\intbl\qc\fs16 104:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1085 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16FEB2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 04MAR2013 / 01:00 (17) \cell +\pard\intbl\qc\fs16 369:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05MAR2013 / 01:00 (18) \cell +\pard\intbl\qc\fs16 04AUG2013 / 00:00 (170) \cell +\pard\intbl\qc\fs16 3647:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05AUG2013 / 16:00 (171) \cell +\pard\intbl\qc\fs16 18AUG2013 / 04:00 (184) \cell +\pard\intbl\qc\fs16 300:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1107 \cell +\pard\intbl\qc\fs16 65 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26FEB2013 / 09:00 (1) \cell +\pard\intbl\qc\fs16 12MAR2013 / 16:00 (15) \cell +\pard\intbl\qc\fs16 343:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13MAR2013 / 03:00 (16) \cell +\pard\intbl\qc\fs16 07MAY2013 / 05:00 (71) \cell +\pard\intbl\qc\fs16 1322:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1405 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Rash, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06JUL2013 / 09:00 (1) \cell +\pard\intbl\qc\fs16 07JUL2013 / 06:00 (2) \cell +\pard\intbl\qc\fs16 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1030 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Rash, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28DEC2013 / 15:00 (1) \cell +\pard\intbl\qc\fs16 02JAN2014 / 10:00 (6) \cell +\pard\intbl\qc\fs16 115:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1063 \cell +\pard\intbl\qc\fs16 80 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09MAY2013 / 10:00 (1) \cell +\pard\intbl\qc\fs16 23MAY2013 / 02:00 (15) \cell +\pard\intbl\qc\fs16 328:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24MAY2013 / 11:00 (16) \cell +\pard\intbl\qc\fs16 25AUG2013 / 09:00 (109) \cell +\pard\intbl\qc\fs16 2230:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1094 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19DEC2012 / 12:00 (1) \cell +\pard\intbl\qc\fs16 06JAN2013 / 16:00 (19) \cell +\pard\intbl\qc\fs16 436:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07JAN2013 / 00:00 (20) \cell +\pard\intbl\qc\fs16 24JAN2013 / 01:00 (37) \cell +\pard\intbl\qc\fs16 409:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1103 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20MAR2014 / 11:00 (1) \cell +\pard\intbl\qc\fs16 05APR2014 / 12:00 (17) \cell +\pard\intbl\qc\fs16 385:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06APR2014 / 00:00 (18) \cell +\pard\intbl\qc\fs16 30AUG2014 / 14:00 (164) \cell +\pard\intbl\qc\fs16 3518:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31AUG2014 / 14:00 (165) \cell +\pard\intbl\qc\fs16 20SEP2014 / 02:00 (185) \cell +\pard\intbl\qc\fs16 468:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1151 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Bladder mapping performed on 20 nov 2023 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01FEB2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 15FEB2013 / 01:00 (15) \cell +\pard\intbl\qc\fs16 333:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16FEB2013 / 02:00 (16) \cell +\pard\intbl\qc\fs16 11MAY2013 / 15:00 (100) \cell +\pard\intbl\qc\fs16 2029:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1157 \cell +\pard\intbl\qc\fs16 85 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02OCT2013 / 01:00 (1) \cell +\pard\intbl\qc\fs16 16OCT2013 / 03:00 (15) \cell +\pard\intbl\qc\fs16 338:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17OCT2013 / 11:00 (16) \cell +\pard\intbl\qc\fs16 26MAR2014 / 00:00 (176) \cell +\pard\intbl\qc\fs16 3829:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Pt had his 24w turb on 22th of december so tar was removed at that time \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27MAR2014 / 19:00 (177) \cell +\pard\intbl\qc\fs16 04APR2014 / 11:00 (185) \cell +\pard\intbl\qc\fs16 184:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1167 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08OCT2012 / 03:00 (1) \cell +\pard\intbl\qc\fs16 29OCT2012 / 00:00 (22) \cell +\pard\intbl\qc\fs16 501:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 30OCT2012 / 09:00 (23) \cell +\pard\intbl\qc\fs16 24MAR2013 / 21:00 (168) \cell +\pard\intbl\qc\fs16 3492:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25MAR2013 / 10:00 (169) \cell +\pard\intbl\qc\fs16 12APR2013 / 05:00 (187) \cell +\pard\intbl\qc\fs16 427:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1298 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08APR2013 / 21:00 (1) \cell +\pard\intbl\qc\fs16 22APR2013 / 04:00 (15) \cell +\pard\intbl\qc\fs16 319:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23APR2013 / 05:00 (16) \cell +\pard\intbl\qc\fs16 28JUN2013 / 11:00 (82) \cell +\pard\intbl\qc\fs16 1590:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1311 \cell +\pard\intbl\qc\fs16 78 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14MAY2014 / 22:00 (1) \cell +\pard\intbl\qc\fs16 28MAY2014 / 11:00 (15) \cell +\pard\intbl\qc\fs16 325:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29MAY2014 / 14:00 (16) \cell +\pard\intbl\qc\fs16 21SEP2014 / 06:00 (131) \cell +\pard\intbl\qc\fs16 2752:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1004 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14JAN2014 / 11:00 (1) \cell +\pard\intbl\qc\fs16 28JAN2014 / 10:00 (15) \cell +\pard\intbl\qc\fs16 335:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29JAN2014 / 10:00 (16) \cell +\pard\intbl\qc\fs16 01JUL2014 / 02:00 (169) \cell +\pard\intbl\qc\fs16 3664:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02JUL2014 / 05:00 (170) \cell +\pard\intbl\qc\fs16 16JUL2014 / 16:00 (184) \cell +\pard\intbl\qc\fs16 347:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1446 \cell +\pard\intbl\qc\fs16 75 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01SEP2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 16SEP2013 / 05:00 (16) \cell +\pard\intbl\qc\fs16 349:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17SEP2013 / 09:00 (17) \cell +\pard\intbl\qc\fs16 16FEB2014 / 10:00 (169) \cell +\pard\intbl\qc\fs16 3649:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17FEB2014 / 23:00 (170) \cell +\pard\intbl\qc\fs16 03MAR2014 / 14:00 (184) \cell +\pard\intbl\qc\fs16 327:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1066 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07JUL2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 16JUL2013 / 17:00 (10) \cell +\pard\intbl\qc\fs16 210:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1079 \cell +\pard\intbl\qc\fs16 67 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19SEP2012 / 13:00 (1) \cell +\pard\intbl\qc\fs16 03OCT2012 / 17:00 (15) \cell +\pard\intbl\qc\fs16 340:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04OCT2012 / 22:00 (16) \cell +\pard\intbl\qc\fs16 31OCT2012 / 07:00 (43) \cell +\pard\intbl\qc\fs16 633:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1170 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Nausea, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Nausea, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16SEP2013 / 02:00 (1) \cell +\pard\intbl\qc\fs16 29SEP2013 / 17:00 (14) \cell +\pard\intbl\qc\fs16 327:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 30SEP2013 / 10:00 (15) \cell +\pard\intbl\qc\fs16 12OCT2013 / 18:00 (27) \cell +\pard\intbl\qc\fs16 296:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1250 \cell +\pard\intbl\qc\fs16 82 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 21SEP2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 03OCT2013 / 18:00 (13) \cell +\pard\intbl\qc\fs16 300:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04OCT2013 / 13:00 (14) \cell +\pard\intbl\qc\fs16 31JAN2014 / 10:00 (133) \cell +\pard\intbl\qc\fs16 2853:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1254 \cell +\pard\intbl\qc\fs16 78 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Sheet could not into the bladder \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10JUL2013 / 09:00 (1) \cell +\pard\intbl\qc\fs16 25JUL2013 / 10:00 (16) \cell +\pard\intbl\qc\fs16 361:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26JUL2013 / 17:00 (17) \cell +\pard\intbl\qc\fs16 26DEC2013 / 06:00 (170) \cell +\pard\intbl\qc\fs16 3661:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27DEC2013 / 17:00 (171) \cell +\pard\intbl\qc\fs16 09JAN2014 / 09:00 (184) \cell +\pard\intbl\qc\fs16 304:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1028 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Bladder mapping performed on 20 nov 2023 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JUL2013 / 08:00 (1) \cell +\pard\intbl\qc\fs16 01AUG2013 / 20:00 (14) \cell +\pard\intbl\qc\fs16 324:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 02AUG2013 / 13:00 (15) \cell +\pard\intbl\qc\fs16 06JAN2014 / 08:00 (172) \cell +\pard\intbl\qc\fs16 3763:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07JAN2014 / 14:00 (173) \cell +\pard\intbl\qc\fs16 14JAN2014 / 15:00 (180) \cell +\pard\intbl\qc\fs16 169:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1034 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01JUL2014 / 12:00 (1) \cell +\pard\intbl\qc\fs16 15JUL2014 / 11:00 (15) \cell +\pard\intbl\qc\fs16 335:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16JUL2014 / 16:00 (16) \cell +\pard\intbl\qc\fs16 17DEC2014 / 10:00 (170) \cell +\pard\intbl\qc\fs16 3690:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18DEC2014 / 08:00 (171) \cell +\pard\intbl\qc\fs16 30DEC2014 / 00:00 (183) \cell +\pard\intbl\qc\fs16 280:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1133 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28OCT2012 / 07:00 (1) \cell +\pard\intbl\qc\fs16 12NOV2012 / 15:00 (16) \cell +\pard\intbl\qc\fs16 368:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 13NOV2012 / 17:00 (17) \cell +\pard\intbl\qc\fs16 18APR2013 / 13:00 (173) \cell +\pard\intbl\qc\fs16 3740:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19APR2013 / 02:00 (174) \cell +\pard\intbl\qc\fs16 28APR2013 / 14:00 (183) \cell +\pard\intbl\qc\fs16 228:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1146 \cell +\pard\intbl\qc\fs16 75 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20MAY2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 03JUN2013 / 06:00 (15) \cell +\pard\intbl\qc\fs16 326:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 04JUN2013 / 06:00 (16) \cell +\pard\intbl\qc\fs16 26JUN2013 / 00:00 (38) \cell +\pard\intbl\qc\fs16 522:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1148 \cell +\pard\intbl\qc\fs16 57 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23AUG2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 05SEP2013 / 15:00 (14) \cell +\pard\intbl\qc\fs16 313:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 06SEP2013 / 20:00 (15) \cell +\pard\intbl\qc\fs16 08FEB2014 / 06:00 (170) \cell +\pard\intbl\qc\fs16 3706:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09FEB2014 / 12:00 (171) \cell +\pard\intbl\qc\fs16 20FEB2014 / 01:00 (182) \cell +\pard\intbl\qc\fs16 253:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1180 \cell +\pard\intbl\qc\fs16 56 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12FEB2013 / 20:00 (1) \cell +\pard\intbl\qc\fs16 25FEB2013 / 15:00 (14) \cell +\pard\intbl\qc\fs16 307:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 26FEB2013 / 17:00 (15) \cell +\pard\intbl\qc\fs16 18MAR2013 / 23:00 (35) \cell +\pard\intbl\qc\fs16 486:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1239 \cell +\pard\intbl\qc\fs16 56 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11JAN2014 / 20:00 (1) \cell +\pard\intbl\qc\fs16 25JAN2014 / 17:00 (15) \cell +\pard\intbl\qc\fs16 333:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 26JAN2014 / 00:00 (16) \cell +\pard\intbl\qc\fs16 27JUN2014 / 14:00 (168) \cell +\pard\intbl\qc\fs16 3662:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28JUN2014 / 23:00 (169) \cell +\pard\intbl\qc\fs16 10JUL2014 / 22:00 (181) \cell +\pard\intbl\qc\fs16 287:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1275 \cell +\pard\intbl\qc\fs16 61 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07FEB2014 / 23:00 (1) \cell +\pard\intbl\qc\fs16 22FEB2014 / 14:00 (16) \cell +\pard\intbl\qc\fs16 351:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 23FEB2014 / 04:00 (17) \cell +\pard\intbl\qc\fs16 31MAY2014 / 08:00 (114) \cell +\pard\intbl\qc\fs16 2332:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1287 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25JAN2014 / 00:00 (1) \cell +\pard\intbl\qc\fs16 11FEB2014 / 03:00 (18) \cell +\pard\intbl\qc\fs16 411:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 12FEB2014 / 12:00 (19) \cell +\pard\intbl\qc\fs16 12JUL2014 / 19:00 (169) \cell +\pard\intbl\qc\fs16 3607:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13JUL2014 / 03:00 (170) \cell +\pard\intbl\qc\fs16 26JUL2014 / 14:00 (183) \cell +\pard\intbl\qc\fs16 323:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1302 \cell +\pard\intbl\qc\fs16 61 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29AUG2013 / 13:00 (1) \cell +\pard\intbl\qc\fs16 15SEP2013 / 22:00 (18) \cell +\pard\intbl\qc\fs16 417:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 16SEP2013 / 07:00 (19) \cell +\pard\intbl\qc\fs16 05NOV2013 / 13:00 (69) \cell +\pard\intbl\qc\fs16 1206:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1383 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Rash, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04FEB2013 / 07:00 (1) \cell +\pard\intbl\qc\fs16 19FEB2013 / 11:00 (16) \cell +\pard\intbl\qc\fs16 364:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 20FEB2013 / 15:00 (17) \cell +\pard\intbl\qc\fs16 30JUL2013 / 06:00 (177) \cell +\pard\intbl\qc\fs16 3831:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31JUL2013 / 15:00 (178) \cell +\pard\intbl\qc\fs16 06AUG2013 / 22:00 (184) \cell +\pard\intbl\qc\fs16 151:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1444 \cell +\pard\intbl\qc\fs16 63 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Suspicion of disease progression \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05JAN2013 / 18:00 (1) \cell +\pard\intbl\qc\fs16 18JAN2013 / 17:00 (14) \cell +\pard\intbl\qc\fs16 311:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Insertion failed \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 19JAN2013 / 13:00 (15) \cell +\pard\intbl\qc\fs16 12FEB2013 / 08:00 (39) \cell +\pard\intbl\qc\fs16 571:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1076 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25OCT2013 / 15:00 (1) \cell +\pard\intbl\qc\fs16 06NOV2013 / 14:00 (13) \cell +\pard\intbl\qc\fs16 287:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 07NOV2013 / 20:00 (14) \cell +\pard\intbl\qc\fs16 24DEC2013 / 18:00 (61) \cell +\pard\intbl\qc\fs16 1126:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1258 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20JUL2012 / 03:00 (1) \cell +\pard\intbl\qc\fs16 01AUG2012 / 20:00 (13) \cell +\pard\intbl\qc\fs16 305:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 02AUG2012 / 20:00 (14) \cell +\pard\intbl\qc\fs16 31DEC2012 / 11:00 (165) \cell +\pard\intbl\qc\fs16 3615:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01JAN2013 / 06:00 (166) \cell +\pard\intbl\qc\fs16 11JAN2013 / 01:00 (176) \cell +\pard\intbl\qc\fs16 235:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1295 \cell +\pard\intbl\qc\fs16 88 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 21NOV2013 / 20:00 (1) \cell +\pard\intbl\qc\fs16 05DEC2013 / 19:00 (15) \cell +\pard\intbl\qc\fs16 335:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 06DEC2013 / 14:00 (16) \cell +\pard\intbl\qc\fs16 19APR2014 / 21:00 (150) \cell +\pard\intbl\qc\fs16 3223:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1335 \cell +\pard\intbl\qc\fs16 67 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17MAR2014 / 00:00 (1) \cell +\pard\intbl\qc\fs16 31MAR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 342:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 01APR2014 / 04:00 (16) \cell +\pard\intbl\qc\fs16 07MAY2014 / 22:00 (52) \cell +\pard\intbl\qc\fs16 882:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1439 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12MAR2014 / 10:00 (1) \cell +\pard\intbl\qc\fs16 26MAR2014 / 22:00 (15) \cell +\pard\intbl\qc\fs16 348:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 27MAR2014 / 16:00 (16) \cell +\pard\intbl\qc\fs16 28AUG2014 / 09:00 (170) \cell +\pard\intbl\qc\fs16 3689:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29AUG2014 / 13:00 (171) \cell +\pard\intbl\qc\fs16 11SEP2014 / 09:00 (184) \cell +\pard\intbl\qc\fs16 308:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1008 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13JAN2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 28JAN2013 / 22:00 (16) \cell +\pard\intbl\qc\fs16 359:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 29JAN2013 / 04:00 (17) \cell +\pard\intbl\qc\fs16 21FEB2013 / 21:00 (40) \cell +\pard\intbl\qc\fs16 569:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1017 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06OCT2013 / 08:00 (1) \cell +\pard\intbl\qc\fs16 19OCT2013 / 16:00 (14) \cell +\pard\intbl\qc\fs16 320:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 20OCT2013 / 22:00 (15) \cell +\pard\intbl\qc\fs16 18NOV2013 / 17:00 (44) \cell +\pard\intbl\qc\fs16 691:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1065 \cell +\pard\intbl\qc\fs16 75 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24OCT2013 / 21:00 (1) \cell +\pard\intbl\qc\fs16 07NOV2013 / 09:00 (15) \cell +\pard\intbl\qc\fs16 324:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 08NOV2013 / 02:00 (16) \cell +\pard\intbl\qc\fs16 22DEC2013 / 23:00 (60) \cell +\pard\intbl\qc\fs16 1077:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1074 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22JAN2014 / 20:00 (1) \cell +\pard\intbl\qc\fs16 09FEB2014 / 11:00 (19) \cell +\pard\intbl\qc\fs16 423:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 10FEB2014 / 11:00 (20) \cell +\pard\intbl\qc\fs16 20MAR2014 / 07:00 (58) \cell +\pard\intbl\qc\fs16 908:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1093 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Nausea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15MAR2013 / 08:00 (1) \cell +\pard\intbl\qc\fs16 30MAR2013 / 08:00 (16) \cell +\pard\intbl\qc\fs16 360:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 31MAR2013 / 20:00 (17) \cell +\pard\intbl\qc\fs16 17JUN2013 / 02:00 (95) \cell +\pard\intbl\qc\fs16 1854:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1241 \cell +\pard\intbl\qc\fs16 86 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25AUG2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 05SEP2013 / 13:00 (12) \cell +\pard\intbl\qc\fs16 254:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 06SEP2013 / 17:00 (13) \cell +\pard\intbl\qc\fs16 09OCT2013 / 02:00 (46) \cell +\pard\intbl\qc\fs16 777:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1266 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13OCT2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 27OCT2013 / 00:00 (15) \cell +\pard\intbl\qc\fs16 314:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 28OCT2013 / 17:00 (16) \cell +\pard\intbl\qc\fs16 06DEC2013 / 01:00 (55) \cell +\pard\intbl\qc\fs16 920:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1332 \cell +\pard\intbl\qc\fs16 80 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09DEC2013 / 15:00 (1) \cell +\pard\intbl\qc\fs16 23DEC2013 / 12:00 (15) \cell +\pard\intbl\qc\fs16 333:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 24DEC2013 / 23:00 (16) \cell +\pard\intbl\qc\fs16 14FEB2014 / 07:00 (68) \cell +\pard\intbl\qc\fs16 1232:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1280 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17JAN2014 / 04:00 (1) \cell +\pard\intbl\qc\fs16 31JAN2014 / 08:00 (15) \cell +\pard\intbl\qc\fs16 340:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 01FEB2014 / 09:00 (16) \cell +\pard\intbl\qc\fs16 11JUL2014 / 07:00 (176) \cell +\pard\intbl\qc\fs16 3838:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12JUL2014 / 16:00 (177) \cell +\pard\intbl\qc\fs16 25JUL2014 / 06:00 (190) \cell +\pard\intbl\qc\fs16 302:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1281 \cell +\pard\intbl\qc\fs16 73 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28NOV2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 15DEC2013 / 07:00 (18) \cell +\pard\intbl\qc\fs16 393:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 16DEC2013 / 19:00 (19) \cell +\pard\intbl\qc\fs16 27FEB2014 / 03:00 (92) \cell +\pard\intbl\qc\fs16 1736:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1303 \cell +\pard\intbl\qc\fs16 72 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16DEC2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 30DEC2013 / 10:00 (15) \cell +\pard\intbl\qc\fs16 343:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Pqc was reported. \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 31DEC2013 / 17:00 (16) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 NA:NA \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1310 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02NOV2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 22NOV2013 / 05:00 (21) \cell +\pard\intbl\qc\fs16 469:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 23NOV2013 / 07:00 (22) \cell +\pard\intbl\qc\fs16 23JAN2014 / 03:00 (83) \cell +\pard\intbl\qc\fs16 1460:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1377 \cell +\pard\intbl\qc\fs16 63 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04JAN2014 / 20:00 (1) \cell +\pard\intbl\qc\fs16 25JAN2014 / 10:00 (22) \cell +\pard\intbl\qc\fs16 494:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 26JAN2014 / 09:00 (23) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 NA:NA \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-706-1049 \cell +\pard\intbl\qc\fs16 60 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14MAY2013 / 10:00 (1) \cell +\pard\intbl\qc\fs16 28MAY2013 / 16:00 (15) \cell +\pard\intbl\qc\fs16 342:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 29MAY2013 / 19:00 (16) \cell +\pard\intbl\qc\fs16 18JUN2013 / 05:00 (36) \cell +\pard\intbl\qc\fs16 466:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1178 \cell +\pard\intbl\qc\fs16 77 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29DEC2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 18JAN2014 / 18:00 (21) \cell +\pard\intbl\qc\fs16 495:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 19JAN2014 / 05:00 (22) \cell +\pard\intbl\qc\fs16 06APR2014 / 22:00 (99) \cell +\pard\intbl\qc\fs16 1865:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1216 \cell +\pard\intbl\qc\fs16 78 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24OCT2012 / 22:00 (1) \cell +\pard\intbl\qc\fs16 08NOV2012 / 21:00 (16) \cell +\pard\intbl\qc\fs16 359:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Vomiting, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Vomiting, Neutropenia) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 09NOV2012 / 10:00 (17) \cell +\pard\intbl\qc\fs16 29NOV2012 / 12:00 (37) \cell +\pard\intbl\qc\fs16 482:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1336 \cell +\pard\intbl\qc\fs16 73 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07DEC2012 / 18:00 (1) \cell +\pard\intbl\qc\fs16 21DEC2012 / 15:00 (15) \cell +\pard\intbl\qc\fs16 333:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 22DEC2012 / 11:00 (16) \cell +\pard\intbl\qc\fs16 22MAY2013 / 01:00 (167) \cell +\pard\intbl\qc\fs16 3614:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23MAY2013 / 01:00 (168) \cell +\pard\intbl\qc\fs16 05JUN2013 / 21:00 (181) \cell +\pard\intbl\qc\fs16 332:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1347 \cell +\pard\intbl\qc\fs16 61 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Fatigue, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20APR2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 04MAY2013 / 04:00 (15) \cell +\pard\intbl\qc\fs16 326:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 05MAY2013 / 12:00 (16) \cell +\pard\intbl\qc\fs16 18JUN2013 / 15:00 (60) \cell +\pard\intbl\qc\fs16 1059:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1406 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Cystoscopy with lesion. Rtu pending \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26DEC2013 / 21:00 (1) \cell +\pard\intbl\qc\fs16 09JAN2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 321:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 10JAN2014 / 06:00 (16) \cell +\pard\intbl\qc\fs16 16JUN2014 / 20:00 (173) \cell +\pard\intbl\qc\fs16 3782:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17JUN2014 / 22:00 (174) \cell +\pard\intbl\qc\fs16 02JUL2014 / 21:00 (189) \cell +\pard\intbl\qc\fs16 359:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1029 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25DEC2012 / 23:00 (1) \cell +\pard\intbl\qc\fs16 09JAN2013 / 05:00 (16) \cell +\pard\intbl\qc\fs16 342:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Vomiting, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 10JAN2013 / 12:00 (17) \cell +\pard\intbl\qc\fs16 12JUN2013 / 04:00 (170) \cell +\pard\intbl\qc\fs16 3664:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13JUN2013 / 09:00 (171) \cell +\pard\intbl\qc\fs16 26JUN2013 / 15:00 (184) \cell +\pard\intbl\qc\fs16 318:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1099 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25OCT2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 12NOV2013 / 15:00 (19) \cell +\pard\intbl\qc\fs16 424:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 13NOV2013 / 21:00 (20) \cell +\pard\intbl\qc\fs16 11APR2014 / 12:00 (169) \cell +\pard\intbl\qc\fs16 3567:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12APR2014 / 13:00 (170) \cell +\pard\intbl\qc\fs16 25APR2014 / 02:00 (183) \cell +\pard\intbl\qc\fs16 301:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1168 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Pt had his 24w turb on 22th of december so tar was removed at that time \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02AUG2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 17AUG2013 / 21:00 (16) \cell +\pard\intbl\qc\fs16 377:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 18AUG2013 / 23:00 (17) \cell +\pard\intbl\qc\fs16 26SEP2013 / 18:00 (56) \cell +\pard\intbl\qc\fs16 931:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1238 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15MAY2013 / 08:00 (1) \cell +\pard\intbl\qc\fs16 29MAY2013 / 05:00 (15) \cell +\pard\intbl\qc\fs16 333:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 30MAY2013 / 14:00 (16) \cell +\pard\intbl\qc\fs16 06AUG2013 / 09:00 (84) \cell +\pard\intbl\qc\fs16 1627:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1309 \cell +\pard\intbl\qc\fs16 65 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JUN2013 / 01:00 (1) \cell +\pard\intbl\qc\fs16 01JUL2013 / 04:00 (13) \cell +\pard\intbl\qc\fs16 291:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 02JUL2013 / 09:00 (14) \cell +\pard\intbl\qc\fs16 05DEC2013 / 23:00 (170) \cell +\pard\intbl\qc\fs16 3758:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06DEC2013 / 17:00 (171) \cell +\pard\intbl\qc\fs16 19DEC2013 / 14:00 (184) \cell +\pard\intbl\qc\fs16 309:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1006 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10FEB2013 / 20:00 (1) \cell +\pard\intbl\qc\fs16 22FEB2013 / 11:00 (13) \cell +\pard\intbl\qc\fs16 279:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 23FEB2013 / 14:00 (14) \cell +\pard\intbl\qc\fs16 27JUL2013 / 20:00 (168) \cell +\pard\intbl\qc\fs16 3702:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Insertion failed \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28JUL2013 / 17:00 (169) \cell +\pard\intbl\qc\fs16 09AUG2013 / 17:00 (181) \cell +\pard\intbl\qc\fs16 288:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1021 \cell +\pard\intbl\qc\fs16 79 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27SEP2013 / 07:00 (1) \cell +\pard\intbl\qc\fs16 11OCT2013 / 21:00 (15) \cell +\pard\intbl\qc\fs16 350:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Pyrexia) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 12OCT2013 / 17:00 (16) \cell +\pard\intbl\qc\fs16 29OCT2013 / 05:00 (33) \cell +\pard\intbl\qc\fs16 396:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1070 \cell +\pard\intbl\qc\fs16 85 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Fatigue, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08SEP2012 / 03:00 (1) \cell +\pard\intbl\qc\fs16 22SEP2012 / 04:00 (15) \cell +\pard\intbl\qc\fs16 337:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 23SEP2012 / 13:00 (16) \cell +\pard\intbl\qc\fs16 22JAN2013 / 02:00 (137) \cell +\pard\intbl\qc\fs16 2893:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1137 \cell +\pard\intbl\qc\fs16 79 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Diarrhoea, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11OCT2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 25OCT2013 / 14:00 (15) \cell +\pard\intbl\qc\fs16 327:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 26OCT2013 / 23:00 (16) \cell +\pard\intbl\qc\fs16 13NOV2013 / 02:00 (34) \cell +\pard\intbl\qc\fs16 411:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1142 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02OCT2012 / 19:00 (1) \cell +\pard\intbl\qc\fs16 16OCT2012 / 14:00 (15) \cell +\pard\intbl\qc\fs16 331:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Insertion failed \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 17OCT2012 / 07:00 (16) \cell +\pard\intbl\qc\fs16 20OCT2012 / 03:00 (19) \cell +\pard\intbl\qc\fs16 68:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1187 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10NOV2012 / 18:00 (1) \cell +\pard\intbl\qc\fs16 24NOV2012 / 04:00 (15) \cell +\pard\intbl\qc\fs16 322:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 25NOV2012 / 14:00 (16) \cell +\pard\intbl\qc\fs16 28APR2013 / 00:00 (170) \cell +\pard\intbl\qc\fs16 3682:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29APR2013 / 06:00 (171) \cell +\pard\intbl\qc\fs16 12MAY2013 / 01:00 (184) \cell +\pard\intbl\qc\fs16 307:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1249 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28DEC2013 / 12:00 (1) \cell +\pard\intbl\qc\fs16 11JAN2014 / 10:00 (15) \cell +\pard\intbl\qc\fs16 334:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 12JAN2014 / 23:00 (16) \cell +\pard\intbl\qc\fs16 14JUN2014 / 12:00 (169) \cell +\pard\intbl\qc\fs16 3661:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15JUN2014 / 13:00 (170) \cell +\pard\intbl\qc\fs16 28JUN2014 / 05:00 (183) \cell +\pard\intbl\qc\fs16 304:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1278 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Pqc was reported. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24DEC2012 / 01:00 (1) \cell +\pard\intbl\qc\fs16 07JAN2013 / 17:00 (15) \cell +\pard\intbl\qc\fs16 352:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 08JAN2013 / 19:00 (16) \cell +\pard\intbl\qc\fs16 26FEB2013 / 13:00 (65) \cell +\pard\intbl\qc\fs16 1170:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1354 \cell +\pard\intbl\qc\fs16 73 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11NOV2012 / 01:00 (1) \cell +\pard\intbl\qc\fs16 25NOV2012 / 19:00 (15) \cell +\pard\intbl\qc\fs16 354:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 26NOV2012 / 21:00 (16) \cell +\pard\intbl\qc\fs16 21APR2013 / 04:00 (162) \cell +\pard\intbl\qc\fs16 3487:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22APR2013 / 07:00 (163) \cell +\pard\intbl\qc\fs16 01MAY2013 / 02:00 (172) \cell +\pard\intbl\qc\fs16 211:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1408 \cell +\pard\intbl\qc\fs16 80 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05JAN2013 / 08:00 (1) \cell +\pard\intbl\qc\fs16 24JAN2013 / 14:00 (20) \cell +\pard\intbl\qc\fs16 462:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 25JAN2013 / 14:00 (21) \cell +\pard\intbl\qc\fs16 28JUN2013 / 08:00 (175) \cell +\pard\intbl\qc\fs16 3690:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Fatigue, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29JUN2013 / 20:00 (176) \cell +\pard\intbl\qc\fs16 12JUL2013 / 03:00 (189) \cell +\pard\intbl\qc\fs16 295:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-711-1012 \cell +\pard\intbl\qc\fs16 67 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Nausea, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03APR2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 17APR2013 / 19:00 (15) \cell +\pard\intbl\qc\fs16 339:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 18APR2013 / 17:00 (16) \cell +\pard\intbl\qc\fs16 29APR2013 / 07:00 (27) \cell +\pard\intbl\qc\fs16 254:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1106 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Pyrexia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31OCT2012 / 21:00 (1) \cell +\pard\intbl\qc\fs16 15NOV2012 / 13:00 (16) \cell +\pard\intbl\qc\fs16 352:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 16NOV2012 / 03:00 (17) \cell +\pard\intbl\qc\fs16 22APR2013 / 15:00 (174) \cell +\pard\intbl\qc\fs16 3780:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Rash, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23APR2013 / 23:00 (175) \cell +\pard\intbl\qc\fs16 06MAY2013 / 02:00 (188) \cell +\pard\intbl\qc\fs16 291:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1141 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31MAY2013 / 10:00 (1) \cell +\pard\intbl\qc\fs16 14JUN2013 / 18:00 (15) \cell +\pard\intbl\qc\fs16 344:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15JUN2013 / 09:00 (16) \cell +\pard\intbl\qc\fs16 01JUL2013 / 09:00 (32) \cell +\pard\intbl\qc\fs16 384:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1209 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27MAY2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 14JUN2013 / 05:00 (19) \cell +\pard\intbl\qc\fs16 434:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15JUN2013 / 09:00 (20) \cell +\pard\intbl\qc\fs16 14NOV2013 / 15:00 (172) \cell +\pard\intbl\qc\fs16 3654:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15NOV2013 / 17:00 (173) \cell +\pard\intbl\qc\fs16 22NOV2013 / 22:00 (180) \cell +\pard\intbl\qc\fs16 173:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1288 \cell +\pard\intbl\qc\fs16 77 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04DEC2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 17DEC2013 / 16:00 (14) \cell +\pard\intbl\qc\fs16 325:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 18DEC2013 / 19:00 (15) \cell +\pard\intbl\qc\fs16 27MAY2014 / 16:00 (175) \cell +\pard\intbl\qc\fs16 3837:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28MAY2014 / 12:00 (176) \cell +\pard\intbl\qc\fs16 17JUN2014 / 23:00 (196) \cell +\pard\intbl\qc\fs16 491:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1319 \cell +\pard\intbl\qc\fs16 65 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17FEB2013 / 09:00 (1) \cell +\pard\intbl\qc\fs16 03MAR2013 / 09:00 (15) \cell +\pard\intbl\qc\fs16 336:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 04MAR2013 / 21:00 (16) \cell +\pard\intbl\qc\fs16 05MAR2013 / 20:00 (17) \cell +\pard\intbl\qc\fs16 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1321 \cell +\pard\intbl\qc\fs16 75 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11FEB2014 / 04:00 (1) \cell +\pard\intbl\qc\fs16 26FEB2014 / 06:00 (16) \cell +\pard\intbl\qc\fs16 362:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 27FEB2014 / 00:00 (17) \cell +\pard\intbl\qc\fs16 21APR2014 / 10:00 (70) \cell +\pard\intbl\qc\fs16 1282:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1071 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08JUN2013 / 12:00 (1) \cell +\pard\intbl\qc\fs16 22JUN2013 / 13:00 (15) \cell +\pard\intbl\qc\fs16 337:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 23JUN2013 / 14:00 (16) \cell +\pard\intbl\qc\fs16 01AUG2013 / 17:00 (55) \cell +\pard\intbl\qc\fs16 939:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1189 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09OCT2012 / 22:00 (1) \cell +\pard\intbl\qc\fs16 24OCT2012 / 05:00 (16) \cell +\pard\intbl\qc\fs16 343:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Pqc \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 25OCT2012 / 13:00 (17) \cell +\pard\intbl\qc\fs16 27FEB2013 / 11:00 (142) \cell +\pard\intbl\qc\fs16 2998:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1229 \cell +\pard\intbl\qc\fs16 73 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20FEB2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 06MAR2013 / 11:00 (15) \cell +\pard\intbl\qc\fs16 324:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Headache, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 07MAR2013 / 06:00 (16) \cell +\pard\intbl\qc\fs16 31MAR2013 / 01:00 (40) \cell +\pard\intbl\qc\fs16 571:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1364 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04JUL2013 / 08:00 (1) \cell +\pard\intbl\qc\fs16 17JUL2013 / 22:00 (14) \cell +\pard\intbl\qc\fs16 326:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 18JUL2013 / 18:00 (15) \cell +\pard\intbl\qc\fs16 23DEC2013 / 06:00 (173) \cell +\pard\intbl\qc\fs16 3780:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24DEC2013 / 14:00 (174) \cell +\pard\intbl\qc\fs16 09JAN2014 / 21:00 (190) \cell +\pard\intbl\qc\fs16 391:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1373 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14DEC2012 / 04:00 (1) \cell +\pard\intbl\qc\fs16 30DEC2012 / 08:00 (17) \cell +\pard\intbl\qc\fs16 388:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 31DEC2012 / 05:00 (18) \cell +\pard\intbl\qc\fs16 27FEB2013 / 09:00 (76) \cell +\pard\intbl\qc\fs16 1396:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1418 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05MAY2013 / 08:00 (1) \cell +\pard\intbl\qc\fs16 19MAY2013 / 10:00 (15) \cell +\pard\intbl\qc\fs16 338:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Pqc was reported. \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 20MAY2013 / 14:00 (16) \cell +\pard\intbl\qc\fs16 06NOV2013 / 20:00 (186) \cell +\pard\intbl\qc\fs16 4086:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Vomiting, Pyrexia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07NOV2013 / 03:00 (187) \cell +\pard\intbl\qc\fs16 20NOV2013 / 09:00 (200) \cell +\pard\intbl\qc\fs16 318:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1447 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Fatigue, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16DEC2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 31DEC2013 / 04:00 (16) \cell +\pard\intbl\qc\fs16 358:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 01JAN2014 / 17:00 (17) \cell +\pard\intbl\qc\fs16 07JUN2014 / 08:00 (174) \cell +\pard\intbl\qc\fs16 3759:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08JUN2014 / 09:00 (175) \cell +\pard\intbl\qc\fs16 17JUN2014 / 19:00 (184) \cell +\pard\intbl\qc\fs16 226:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1109 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27JAN2014 / 10:00 (1) \cell +\pard\intbl\qc\fs16 10FEB2014 / 08:00 (15) \cell +\pard\intbl\qc\fs16 334:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Due to personal schedule \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 11FEB2014 / 08:00 (16) \cell +\pard\intbl\qc\fs16 18JUL2014 / 12:00 (173) \cell +\pard\intbl\qc\fs16 3772:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JUL2014 / 18:00 (174) \cell +\pard\intbl\qc\fs16 28JUL2014 / 08:00 (183) \cell +\pard\intbl\qc\fs16 206:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1174 \cell +\pard\intbl\qc\fs16 73 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22JAN2013 / 18:00 (1) \cell +\pard\intbl\qc\fs16 04FEB2013 / 08:00 (14) \cell +\pard\intbl\qc\fs16 302:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 05FEB2013 / 01:00 (15) \cell +\pard\intbl\qc\fs16 07JUL2013 / 15:00 (167) \cell +\pard\intbl\qc\fs16 3662:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08JUL2013 / 21:00 (168) \cell +\pard\intbl\qc\fs16 24JUL2013 / 11:00 (184) \cell +\pard\intbl\qc\fs16 374:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1357 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Progression \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01MAY2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 15MAY2013 / 19:00 (15) \cell +\pard\intbl\qc\fs16 333:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 16MAY2013 / 00:00 (16) \cell +\pard\intbl\qc\fs16 14OCT2013 / 02:00 (167) \cell +\pard\intbl\qc\fs16 3626:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1101 \cell +\pard\intbl\qc\fs16 82 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17FEB2013 / 10:00 (1) \cell +\pard\intbl\qc\fs16 03MAR2013 / 01:00 (15) \cell +\pard\intbl\qc\fs16 327:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 04MAR2013 / 02:00 (16) \cell +\pard\intbl\qc\fs16 31JUL2013 / 03:00 (165) \cell +\pard\intbl\qc\fs16 3577:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1328 \cell +\pard\intbl\qc\fs16 86 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Rash, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01FEB2013 / 18:00 (1) \cell +\pard\intbl\qc\fs16 14FEB2013 / 09:00 (14) \cell +\pard\intbl\qc\fs16 303:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15FEB2013 / 07:00 (15) \cell +\pard\intbl\qc\fs16 18APR2013 / 14:00 (77) \cell +\pard\intbl\qc\fs16 1495:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1371 \cell +\pard\intbl\qc\fs16 69 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26APR2013 / 21:00 (1) \cell +\pard\intbl\qc\fs16 08MAY2013 / 17:00 (13) \cell +\pard\intbl\qc\fs16 284:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Tar200 was half blocked by the exit port of the upc \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 09MAY2013 / 21:00 (14) \cell +\pard\intbl\qc\fs16 01AUG2013 / 05:00 (98) \cell +\pard\intbl\qc\fs16 2000:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1427 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17DEC2012 / 23:00 (1) \cell +\pard\intbl\qc\fs16 31DEC2012 / 09:00 (15) \cell +\pard\intbl\qc\fs16 322:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell \pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 960 mg \cell -\pard\intbl\qc\fs16 18AUG2013 / 03:00 (17) \cell -\pard\intbl\qc\fs16 26SEP2013 / --:-- (56) \cell -\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 01JAN2013 / 06:00 (16) \cell +\pard\intbl\qc\fs16 11FEB2013 / 05:00 (57) \cell +\pard\intbl\qc\fs16 983:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-701-1015 \cell +\pard\intbl\qc\fs16 63 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02JAN2014 / 02:00 (1) \cell +\pard\intbl\qc\fs16 16JAN2014 / 12:00 (15) \cell +\pard\intbl\qc\fs16 346:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17JAN2014 / 02:00 (16) \cell +\pard\intbl\qc\fs16 18JUN2014 / 19:00 (168) \cell +\pard\intbl\qc\fs16 3665:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19JUN2014 / 00:00 (169) \cell +\pard\intbl\qc\fs16 02JUL2014 / 22:00 (182) \cell +\pard\intbl\qc\fs16 334:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1023 \cell +\pard\intbl\qc\fs16 64 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05AUG2012 / 16:00 (1) \cell +\pard\intbl\qc\fs16 27AUG2012 / 08:00 (23) \cell +\pard\intbl\qc\fs16 520:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28AUG2012 / 17:00 (24) \cell +\pard\intbl\qc\fs16 01SEP2012 / 20:00 (28) \cell +\pard\intbl\qc\fs16 99:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1047 \cell +\pard\intbl\qc\fs16 85 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12FEB2013 / 08:00 (1) \cell +\pard\intbl\qc\fs16 25FEB2013 / 20:00 (14) \cell +\pard\intbl\qc\fs16 324:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26FEB2013 / 07:00 (15) \cell +\pard\intbl\qc\fs16 09MAR2013 / 02:00 (26) \cell +\pard\intbl\qc\fs16 259:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1118 \cell +\pard\intbl\qc\fs16 52 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Vomiting, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12MAR2014 / 17:00 (1) \cell +\pard\intbl\qc\fs16 26MAR2014 / 06:00 (15) \cell +\pard\intbl\qc\fs16 325:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27MAR2014 / 21:00 (16) \cell +\pard\intbl\qc\fs16 27AUG2014 / 10:00 (169) \cell +\pard\intbl\qc\fs16 3661:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28AUG2014 / 14:00 (170) \cell +\pard\intbl\qc\fs16 09SEP2014 / 18:00 (182) \cell +\pard\intbl\qc\fs16 292:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1130 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Vomiting, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 15FEB2014 / 11:00 (1) \cell +\pard\intbl\qc\fs16 01MAR2014 / 05:00 (15) \cell +\pard\intbl\qc\fs16 330:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02MAR2014 / 10:00 (16) \cell +\pard\intbl\qc\fs16 02AUG2014 / 15:00 (169) \cell +\pard\intbl\qc\fs16 3677:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03AUG2014 / 00:00 (170) \cell +\pard\intbl\qc\fs16 16AUG2014 / 12:00 (183) \cell +\pard\intbl\qc\fs16 324:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1153 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23SEP2013 / 20:00 (1) \cell +\pard\intbl\qc\fs16 08OCT2013 / 01:00 (16) \cell +\pard\intbl\qc\fs16 341:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09OCT2013 / 06:00 (17) \cell +\pard\intbl\qc\fs16 11MAR2014 / 04:00 (170) \cell +\pard\intbl\qc\fs16 3670:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12MAR2014 / 08:00 (171) \cell +\pard\intbl\qc\fs16 16MAR2014 / 23:00 (175) \cell +\pard\intbl\qc\fs16 111:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1203 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Rash, Pyrexia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02FEB2013 / 11:00 (1) \cell +\pard\intbl\qc\fs16 23FEB2013 / 08:00 (22) \cell +\pard\intbl\qc\fs16 501:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Sheet could not into the bladder \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24FEB2013 / 06:00 (23) \cell +\pard\intbl\qc\fs16 22JUL2013 / 19:00 (171) \cell +\pard\intbl\qc\fs16 3565:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23JUL2013 / 11:00 (172) \cell +\pard\intbl\qc\fs16 03AUG2013 / 20:00 (183) \cell +\pard\intbl\qc\fs16 273:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1234 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 30MAR2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 21APR2013 / 00:00 (23) \cell +\pard\intbl\qc\fs16 525:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22APR2013 / 00:00 (24) \cell +\pard\intbl\qc\fs16 10SEP2013 / 15:00 (165) \cell +\pard\intbl\qc\fs16 3399:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11SEP2013 / 05:00 (166) \cell +\pard\intbl\qc\fs16 22SEP2013 / 07:00 (177) \cell +\pard\intbl\qc\fs16 266:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1345 \cell +\pard\intbl\qc\fs16 63 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08OCT2013 / 00:00 (1) \cell +\pard\intbl\qc\fs16 24OCT2013 / 22:00 (17) \cell +\pard\intbl\qc\fs16 406:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25OCT2013 / 16:00 (18) \cell +\pard\intbl\qc\fs16 18MAR2014 / 00:00 (162) \cell +\pard\intbl\qc\fs16 3440:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1363 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 30MAY2013 / 15:00 (1) \cell +\pard\intbl\qc\fs16 12JUN2013 / 13:00 (14) \cell +\pard\intbl\qc\fs16 310:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13JUN2013 / 18:00 (15) \cell +\pard\intbl\qc\fs16 13NOV2013 / 20:00 (168) \cell +\pard\intbl\qc\fs16 3674:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14NOV2013 / 08:00 (169) \cell +\pard\intbl\qc\fs16 27NOV2013 / 01:00 (182) \cell +\pard\intbl\qc\fs16 305:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1387 \cell +\pard\intbl\qc\fs16 87 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Sheet could not into the bladder \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12MAR2014 / 15:00 (1) \cell +\pard\intbl\qc\fs16 25MAR2014 / 22:00 (14) \cell +\pard\intbl\qc\fs16 319:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1392 \cell +\pard\intbl\qc\fs16 78 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28OCT2012 / 10:00 (1) \cell +\pard\intbl\qc\fs16 11NOV2012 / 20:00 (15) \cell +\pard\intbl\qc\fs16 346:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12NOV2012 / 22:00 (16) \cell +\pard\intbl\qc\fs16 15APR2013 / 22:00 (170) \cell +\pard\intbl\qc\fs16 3696:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16APR2013 / 19:00 (171) \cell +\pard\intbl\qc\fs16 28APR2013 / 00:00 (183) \cell +\pard\intbl\qc\fs16 269:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1415 \cell +\pard\intbl\qc\fs16 85 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23SEP2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 07OCT2013 / 18:00 (15) \cell +\pard\intbl\qc\fs16 350:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08OCT2013 / 03:00 (16) \cell +\pard\intbl\qc\fs16 10MAR2014 / 02:00 (169) \cell +\pard\intbl\qc\fs16 3671:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11MAR2014 / 09:00 (170) \cell +\pard\intbl\qc\fs16 24MAR2014 / 03:00 (183) \cell +\pard\intbl\qc\fs16 306:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1440 \cell +\pard\intbl\qc\fs16 70 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08AUG2013 / 05:00 (1) \cell +\pard\intbl\qc\fs16 23AUG2013 / 20:00 (16) \cell +\pard\intbl\qc\fs16 375:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Nausea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24AUG2013 / 19:00 (17) \cell +\pard\intbl\qc\fs16 22JAN2014 / 10:00 (168) \cell +\pard\intbl\qc\fs16 3615:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Drug was never administered because the subject dropped out prior to first dose \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23JAN2014 / 10:00 (169) \cell +\pard\intbl\qc\fs16 05FEB2014 / 16:00 (182) \cell +\pard\intbl\qc\fs16 318:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1042 \cell +\pard\intbl\qc\fs16 64 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Rash, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02MAR2013 / 18:00 (1) \cell +\pard\intbl\qc\fs16 14MAR2013 / 20:00 (13) \cell +\pard\intbl\qc\fs16 290:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 15MAR2013 / 14:00 (14) \cell +\pard\intbl\qc\fs16 09AUG2013 / 03:00 (161) \cell +\pard\intbl\qc\fs16 3517:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10AUG2013 / 19:00 (162) \cell +\pard\intbl\qc\fs16 31AUG2013 / 04:00 (183) \cell +\pard\intbl\qc\fs16 489:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1096 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Suspicion of disease progression \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25JAN2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 09FEB2013 / 09:00 (16) \cell +\pard\intbl\qc\fs16 346:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10FEB2013 / 23:00 (17) \cell +\pard\intbl\qc\fs16 16MAR2013 / 22:00 (51) \cell +\pard\intbl\qc\fs16 815:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1100 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13MAR2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 29MAR2013 / 22:00 (17) \cell +\pard\intbl\qc\fs16 402:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Vomiting, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 30MAR2013 / 06:00 (18) \cell +\pard\intbl\qc\fs16 28AUG2013 / 20:00 (169) \cell +\pard\intbl\qc\fs16 3638:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 29AUG2013 / 20:00 (170) \cell +\pard\intbl\qc\fs16 14SEP2013 / 06:00 (186) \cell +\pard\intbl\qc\fs16 370:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1175 \cell +\pard\intbl\qc\fs16 75 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Cystoscopy with lesion. Rtu pending \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20DEC2013 / 01:00 (1) \cell +\pard\intbl\qc\fs16 26DEC2013 / 22:00 (7) \cell +\pard\intbl\qc\fs16 165:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1210 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16MAR2013 / 10:00 (1) \cell +\pard\intbl\qc\fs16 30MAR2013 / 03:00 (15) \cell +\pard\intbl\qc\fs16 329:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 31MAR2013 / 09:00 (16) \cell +\pard\intbl\qc\fs16 24AUG2013 / 22:00 (162) \cell +\pard\intbl\qc\fs16 3517:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25AUG2013 / 09:00 (163) \cell +\pard\intbl\qc\fs16 06SEP2013 / 03:00 (175) \cell +\pard\intbl\qc\fs16 282:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1299 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12SEP2012 / 12:00 (1) \cell +\pard\intbl\qc\fs16 28SEP2012 / 17:00 (17) \cell +\pard\intbl\qc\fs16 389:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: The device could not push tar-200 out. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 29SEP2012 / 04:00 (18) \cell +\pard\intbl\qc\fs16 01MAR2013 / 16:00 (171) \cell +\pard\intbl\qc\fs16 3684:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02MAR2013 / 14:00 (172) \cell +\pard\intbl\qc\fs16 13MAR2013 / 08:00 (183) \cell +\pard\intbl\qc\fs16 258:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1010 \cell +\pard\intbl\qc\fs16 80 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 21FEB2014 / 02:00 (1) \cell +\pard\intbl\qc\fs16 08MAR2014 / 11:00 (16) \cell +\pard\intbl\qc\fs16 369:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Pt had his 24w turb on 22th of december so tar was removed at that time \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09MAR2014 / 15:00 (17) \cell +\pard\intbl\qc\fs16 08JUL2014 / 23:00 (138) \cell +\pard\intbl\qc\fs16 2912:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1127 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02OCT2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 16OCT2013 / 11:00 (15) \cell +\pard\intbl\qc\fs16 324:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17OCT2013 / 00:00 (16) \cell +\pard\intbl\qc\fs16 17MAR2014 / 10:00 (167) \cell +\pard\intbl\qc\fs16 3634:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18MAR2014 / 10:00 (168) \cell +\pard\intbl\qc\fs16 31MAR2014 / 22:00 (181) \cell +\pard\intbl\qc\fs16 324:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1164 \cell +\pard\intbl\qc\fs16 67 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19SEP2012 / 02:00 (1) \cell +\pard\intbl\qc\fs16 04OCT2012 / 15:00 (16) \cell +\pard\intbl\qc\fs16 373:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05OCT2012 / 21:00 (17) \cell +\pard\intbl\qc\fs16 17MAR2013 / 00:00 (180) \cell +\pard\intbl\qc\fs16 3891:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18MAR2013 / 06:00 (181) \cell +\pard\intbl\qc\fs16 04APR2013 / 09:00 (198) \cell +\pard\intbl\qc\fs16 411:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1233 \cell +\pard\intbl\qc\fs16 87 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 21MAR2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 04APR2013 / 11:00 (15) \cell +\pard\intbl\qc\fs16 343:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05APR2013 / 19:00 (16) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 NA:NA \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1260 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 30AUG2012 / 11:00 (1) \cell +\pard\intbl\qc\fs16 13SEP2012 / 04:00 (15) \cell +\pard\intbl\qc\fs16 329:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14SEP2012 / 15:00 (16) \cell +\pard\intbl\qc\fs16 04NOV2012 / 11:00 (67) \cell +\pard\intbl\qc\fs16 1220:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1351 \cell +\pard\intbl\qc\fs16 70 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12OCT2013 / 05:00 (1) \cell +\pard\intbl\qc\fs16 26OCT2013 / 18:00 (15) \cell +\pard\intbl\qc\fs16 349:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27OCT2013 / 08:00 (16) \cell +\pard\intbl\qc\fs16 04APR2014 / 21:00 (175) \cell +\pard\intbl\qc\fs16 3829:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Headache, Pyrexia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05APR2014 / 08:00 (176) \cell +\pard\intbl\qc\fs16 18APR2014 / 00:00 (189) \cell +\pard\intbl\qc\fs16 304:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1388 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Headache, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache, Pyrexia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 07DEC2012 / 20:00 (1) \cell +\pard\intbl\qc\fs16 21DEC2012 / 02:00 (15) \cell +\pard\intbl\qc\fs16 318:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22DEC2012 / 05:00 (16) \cell +\pard\intbl\qc\fs16 23MAY2013 / 04:00 (168) \cell +\pard\intbl\qc\fs16 3647:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24MAY2013 / 06:00 (169) \cell +\pard\intbl\qc\fs16 11JUN2013 / 22:00 (187) \cell +\pard\intbl\qc\fs16 448:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1435 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17NOV2012 / 15:00 (1) \cell +\pard\intbl\qc\fs16 01DEC2012 / 01:00 (15) \cell +\pard\intbl\qc\fs16 322:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02DEC2012 / 07:00 (16) \cell +\pard\intbl\qc\fs16 09JAN2013 / 06:00 (54) \cell +\pard\intbl\qc\fs16 911:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1445 \cell +\pard\intbl\qc\fs16 75 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11MAY2014 / 14:00 (1) \cell +\pard\intbl\qc\fs16 25MAY2014 / 21:00 (15) \cell +\pard\intbl\qc\fs16 343:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26MAY2014 / 20:00 (16) \cell +\pard\intbl\qc\fs16 01NOV2014 / 16:00 (175) \cell +\pard\intbl\qc\fs16 3812:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1018 \cell +\pard\intbl\qc\fs16 69 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05JUL2013 / 01:00 (1) \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 NA:NA \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1059 \cell +\pard\intbl\qc\fs16 66 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Diarrhoea, Anaemia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05AUG2013 / 10:00 (1) \cell +\pard\intbl\qc\fs16 19AUG2013 / 03:00 (15) \cell +\pard\intbl\qc\fs16 329:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Vomiting, Anaemia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20AUG2013 / 10:00 (16) \cell +\pard\intbl\qc\fs16 05DEC2013 / 01:00 (123) \cell +\pard\intbl\qc\fs16 2559:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1186 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08JAN2014 / 23:00 (1) \cell +\pard\intbl\qc\fs16 23JAN2014 / 03:00 (16) \cell +\pard\intbl\qc\fs16 340:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24JAN2014 / 23:00 (17) \cell +\pard\intbl\qc\fs16 26JAN2014 / 07:00 (19) \cell +\pard\intbl\qc\fs16 32:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1282 \cell +\pard\intbl\qc\fs16 70 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26DEC2012 / 22:00 (1) \cell +\pard\intbl\qc\fs16 09JAN2013 / 21:00 (15) \cell +\pard\intbl\qc\fs16 335:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10JAN2013 / 04:00 (16) \cell +\pard\intbl\qc\fs16 11JUN2013 / 20:00 (168) \cell +\pard\intbl\qc\fs16 3664:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: The device could not push tar-200 out. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12JUN2013 / 21:00 (169) \cell +\pard\intbl\qc\fs16 24JUN2013 / 18:00 (181) \cell +\pard\intbl\qc\fs16 285:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1349 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10MAR2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 24MAR2013 / 00:00 (15) \cell +\pard\intbl\qc\fs16 333:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25MAR2013 / 22:00 (16) \cell +\pard\intbl\qc\fs16 25AUG2013 / 18:00 (169) \cell +\pard\intbl\qc\fs16 3668:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26AUG2013 / 20:00 (170) \cell +\pard\intbl\qc\fs16 08SEP2013 / 02:00 (183) \cell +\pard\intbl\qc\fs16 294:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-706-1041 \cell +\pard\intbl\qc\fs16 64 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Tar200 was half blocked by the exit port of the upc \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 31DEC2013 / 15:00 (1) \cell +\pard\intbl\qc\fs16 14JAN2014 / 07:00 (15) \cell +\pard\intbl\qc\fs16 328:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 15JAN2014 / 10:00 (16) \cell +\pard\intbl\qc\fs16 15JUL2014 / 20:00 (197) \cell +\pard\intbl\qc\fs16 4354:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16JUL2014 / 14:00 (198) \cell +\pard\intbl\qc\fs16 28JUL2014 / 11:00 (210) \cell +\pard\intbl\qc\fs16 285:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-707-1206 \cell +\pard\intbl\qc\fs16 65 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Personal reasons \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28OCT2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 12NOV2013 / 20:00 (16) \cell +\pard\intbl\qc\fs16 358:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13NOV2013 / 03:00 (17) \cell +\pard\intbl\qc\fs16 13APR2014 / 19:00 (168) \cell +\pard\intbl\qc\fs16 3640:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14APR2014 / 02:00 (169) \cell +\pard\intbl\qc\fs16 26APR2014 / 12:00 (181) \cell +\pard\intbl\qc\fs16 298:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1087 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Rash, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22OCT2012 / 04:00 (1) \cell +\pard\intbl\qc\fs16 05NOV2012 / 18:00 (15) \cell +\pard\intbl\qc\fs16 350:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06NOV2012 / 16:00 (16) \cell +\pard\intbl\qc\fs16 10APR2013 / 08:00 (171) \cell +\pard\intbl\qc\fs16 3712:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11APR2013 / 13:00 (172) \cell +\pard\intbl\qc\fs16 28APR2013 / 14:00 (189) \cell +\pard\intbl\qc\fs16 409:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1158 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08FEB2014 / 02:00 (1) \cell +\pard\intbl\qc\fs16 26FEB2014 / 05:00 (19) \cell +\pard\intbl\qc\fs16 435:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Urine culture not disponible \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27FEB2014 / 14:00 (20) \cell +\pard\intbl\qc\fs16 21MAR2014 / 08:00 (42) \cell +\pard\intbl\qc\fs16 522:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1171 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06DEC2012 / 23:00 (1) \cell +\pard\intbl\qc\fs16 18DEC2012 / 21:00 (13) \cell +\pard\intbl\qc\fs16 286:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19DEC2012 / 14:00 (14) \cell +\pard\intbl\qc\fs16 20MAY2013 / 15:00 (166) \cell +\pard\intbl\qc\fs16 3649:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 21MAY2013 / 22:00 (167) \cell +\pard\intbl\qc\fs16 04JUN2013 / 19:00 (181) \cell +\pard\intbl\qc\fs16 333:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1253 \cell +\pard\intbl\qc\fs16 61 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 07MAY2013 / 00:00 (1) \cell +\pard\intbl\qc\fs16 21MAY2013 / 15:00 (15) \cell +\pard\intbl\qc\fs16 351:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22MAY2013 / 00:00 (16) \cell +\pard\intbl\qc\fs16 27OCT2013 / 10:00 (174) \cell +\pard\intbl\qc\fs16 3802:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Tar-200 did not take the pretzel shape inside the bladder. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28OCT2013 / 11:00 (175) \cell +\pard\intbl\qc\fs16 05NOV2013 / 22:00 (183) \cell +\pard\intbl\qc\fs16 203:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1286 \cell +\pard\intbl\qc\fs16 80 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10SEP2013 / 19:00 (1) \cell +\pard\intbl\qc\fs16 23SEP2013 / 03:00 (14) \cell +\pard\intbl\qc\fs16 296:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24SEP2013 / 19:00 (15) \cell +\pard\intbl\qc\fs16 23FEB2014 / 14:00 (167) \cell +\pard\intbl\qc\fs16 3643:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24FEB2014 / 01:00 (168) \cell +\pard\intbl\qc\fs16 08MAR2014 / 15:00 (180) \cell +\pard\intbl\qc\fs16 302:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1296 \cell +\pard\intbl\qc\fs16 57 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Vomiting, Neutropenia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14JUN2013 / 18:00 (1) \cell +\pard\intbl\qc\fs16 27JUN2013 / 09:00 (14) \cell +\pard\intbl\qc\fs16 303:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Tar-200 did not take the pretzel shape inside the bladder. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28JUN2013 / 13:00 (15) \cell +\pard\intbl\qc\fs16 27NOV2013 / 10:00 (167) \cell +\pard\intbl\qc\fs16 3645:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28NOV2013 / 14:00 (168) \cell +\pard\intbl\qc\fs16 12DEC2013 / 19:00 (182) \cell +\pard\intbl\qc\fs16 341:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1316 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23AUG2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 05SEP2013 / 18:00 (14) \cell +\pard\intbl\qc\fs16 316:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06SEP2013 / 16:00 (15) \cell +\pard\intbl\qc\fs16 15FEB2014 / 00:00 (177) \cell +\pard\intbl\qc\fs16 3872:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16FEB2014 / 16:00 (178) \cell +\pard\intbl\qc\fs16 01MAR2014 / 04:00 (191) \cell +\pard\intbl\qc\fs16 300:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1342 \cell +\pard\intbl\qc\fs16 59 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 29DEC2012 / 06:00 (1) \cell +\pard\intbl\qc\fs16 12JAN2013 / 22:00 (15) \cell +\pard\intbl\qc\fs16 352:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13JAN2013 / 14:00 (16) \cell +\pard\intbl\qc\fs16 15JUN2013 / 19:00 (169) \cell +\pard\intbl\qc\fs16 3677:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16JUN2013 / 02:00 (170) \cell +\pard\intbl\qc\fs16 28JUN2013 / 09:00 (182) \cell +\pard\intbl\qc\fs16 295:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1378 \cell +\pard\intbl\qc\fs16 67 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03SEP2013 / 01:00 (1) \cell +\pard\intbl\qc\fs16 21SEP2013 / 09:00 (19) \cell +\pard\intbl\qc\fs16 440:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22SEP2013 / 00:00 (20) \cell +\pard\intbl\qc\fs16 28JAN2014 / 09:00 (148) \cell +\pard\intbl\qc\fs16 3081:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1001 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08OCT2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 22OCT2013 / 14:00 (15) \cell +\pard\intbl\qc\fs16 336:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23OCT2013 / 01:00 (16) \cell +\pard\intbl\qc\fs16 17MAR2014 / 05:00 (161) \cell +\pard\intbl\qc\fs16 3484:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18MAR2014 / 14:00 (162) \cell +\pard\intbl\qc\fs16 08APR2014 / 04:00 (183) \cell +\pard\intbl\qc\fs16 494:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1088 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12APR2014 / 20:00 (1) \cell +\pard\intbl\qc\fs16 26APR2014 / 17:00 (15) \cell +\pard\intbl\qc\fs16 333:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27APR2014 / 01:00 (16) \cell +\pard\intbl\qc\fs16 27SEP2014 / 03:00 (169) \cell +\pard\intbl\qc\fs16 3674:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28SEP2014 / 04:00 (170) \cell +\pard\intbl\qc\fs16 09OCT2014 / 12:00 (181) \cell +\pard\intbl\qc\fs16 272:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1259 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Progression \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26JAN2013 / 17:00 (1) \cell +\pard\intbl\qc\fs16 10FEB2013 / 19:00 (16) \cell +\pard\intbl\qc\fs16 362:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was reported. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11FEB2013 / 13:00 (17) \cell +\pard\intbl\qc\fs16 13JUN2013 / 20:00 (139) \cell +\pard\intbl\qc\fs16 2935:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1301 \cell +\pard\intbl\qc\fs16 62 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19JUL2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 02AUG2013 / 02:00 (15) \cell +\pard\intbl\qc\fs16 315:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03AUG2013 / 07:00 (16) \cell +\pard\intbl\qc\fs16 04JAN2014 / 09:00 (170) \cell +\pard\intbl\qc\fs16 3698:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05JAN2014 / 02:00 (171) \cell +\pard\intbl\qc\fs16 17JAN2014 / 17:00 (183) \cell +\pard\intbl\qc\fs16 303:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1306 \cell +\pard\intbl\qc\fs16 60 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03FEB2014 / 03:00 (1) \cell +\pard\intbl\qc\fs16 19FEB2014 / 19:00 (17) \cell +\pard\intbl\qc\fs16 400:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20FEB2014 / 16:00 (18) \cell +\pard\intbl\qc\fs16 16JUN2014 / 17:00 (134) \cell +\pard\intbl\qc\fs16 2785:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1312 \cell +\pard\intbl\qc\fs16 68 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20APR2014 / 23:00 (1) \cell +\pard\intbl\qc\fs16 10MAY2014 / 14:00 (21) \cell +\pard\intbl\qc\fs16 471:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting, Neutropenia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11MAY2014 / 04:00 (22) \cell +\pard\intbl\qc\fs16 05OCT2014 / 14:00 (169) \cell +\pard\intbl\qc\fs16 3538:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06OCT2014 / 04:00 (170) \cell +\pard\intbl\qc\fs16 19OCT2014 / 01:00 (183) \cell +\pard\intbl\qc\fs16 309:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1339 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23DEC2012 / 11:00 (1) \cell +\pard\intbl\qc\fs16 05JAN2013 / 18:00 (14) \cell +\pard\intbl\qc\fs16 319:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06JAN2013 / 13:00 (15) \cell +\pard\intbl\qc\fs16 08JUN2013 / 04:00 (168) \cell +\pard\intbl\qc\fs16 3663:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09JUN2013 / 18:00 (169) \cell +\pard\intbl\qc\fs16 24JUN2013 / 03:00 (184) \cell +\pard\intbl\qc\fs16 345:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1027 \cell +\pard\intbl\qc\fs16 83 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28FEB2014 / 17:00 (1) \cell +\pard\intbl\qc\fs16 14MAR2014 / 05:00 (15) \cell +\pard\intbl\qc\fs16 324:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 15MAR2014 / 07:00 (16) \cell +\pard\intbl\qc\fs16 19AUG2014 / 15:00 (173) \cell +\pard\intbl\qc\fs16 3776:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Bladder mapping performed on 20 nov 2023 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20AUG2014 / 16:00 (174) \cell +\pard\intbl\qc\fs16 29AUG2014 / 14:00 (183) \cell +\pard\intbl\qc\fs16 214:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1060 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 01JAN2013 / 04:00 (1) \cell +\pard\intbl\qc\fs16 15JAN2013 / 21:00 (15) \cell +\pard\intbl\qc\fs16 353:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Diarrhoea, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16JAN2013 / 01:00 (16) \cell +\pard\intbl\qc\fs16 21JUN2013 / 07:00 (172) \cell +\pard\intbl\qc\fs16 3750:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Nausea, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22JUN2013 / 00:00 (173) \cell +\pard\intbl\qc\fs16 05JUL2013 / 14:00 (186) \cell +\pard\intbl\qc\fs16 326:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1077 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17NOV2013 / 16:00 (1) \cell +\pard\intbl\qc\fs16 01DEC2013 / 10:00 (15) \cell +\pard\intbl\qc\fs16 330:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02DEC2013 / 19:00 (16) \cell +\pard\intbl\qc\fs16 03MAY2014 / 03:00 (168) \cell +\pard\intbl\qc\fs16 3632:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 04MAY2014 / 15:00 (169) \cell +\pard\intbl\qc\fs16 18MAY2014 / 06:00 (183) \cell +\pard\intbl\qc\fs16 327:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1078 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17SEP2013 / 01:00 (1) \cell +\pard\intbl\qc\fs16 06OCT2013 / 13:00 (20) \cell +\pard\intbl\qc\fs16 468:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 07OCT2013 / 23:00 (21) \cell +\pard\intbl\qc\fs16 08MAR2014 / 09:00 (173) \cell +\pard\intbl\qc\fs16 3634:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09MAR2014 / 21:00 (174) \cell +\pard\intbl\qc\fs16 23MAR2014 / 21:00 (188) \cell +\pard\intbl\qc\fs16 336:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1083 \cell +\pard\intbl\qc\fs16 89 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22JUL2013 / 20:00 (1) \cell +\pard\intbl\qc\fs16 01AUG2013 / 19:00 (11) \cell +\pard\intbl\qc\fs16 239:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1183 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16NOV2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 30NOV2013 / 13:00 (15) \cell +\pard\intbl\qc\fs16 327:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 01DEC2013 / 21:00 (16) \cell +\pard\intbl\qc\fs16 03MAY2014 / 00:00 (169) \cell +\pard\intbl\qc\fs16 3651:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 04MAY2014 / 12:00 (170) \cell +\pard\intbl\qc\fs16 17MAY2014 / 17:00 (183) \cell +\pard\intbl\qc\fs16 317:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1264 \cell +\pard\intbl\qc\fs16 78 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13JUN2013 / 15:00 (1) \cell +\pard\intbl\qc\fs16 27JUN2013 / 04:00 (15) \cell +\pard\intbl\qc\fs16 325:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28JUN2013 / 02:00 (16) \cell +\pard\intbl\qc\fs16 11OCT2013 / 15:00 (121) \cell +\pard\intbl\qc\fs16 2533:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1271 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Headache, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27SEP2012 / 15:00 (1) \cell +\pard\intbl\qc\fs16 12OCT2012 / 02:00 (16) \cell +\pard\intbl\qc\fs16 347:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13OCT2012 / 18:00 (17) \cell +\pard\intbl\qc\fs16 21NOV2012 / 18:00 (56) \cell +\pard\intbl\qc\fs16 936:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1314 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Diarrhoea, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24APR2013 / 01:00 (1) \cell +\pard\intbl\qc\fs16 09MAY2013 / 20:00 (16) \cell +\pard\intbl\qc\fs16 379:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10MAY2013 / 23:00 (17) \cell +\pard\intbl\qc\fs16 23MAY2013 / 08:00 (30) \cell +\pard\intbl\qc\fs16 297:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1315 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27FEB2013 / 06:00 (1) \cell +\pard\intbl\qc\fs16 13MAR2013 / 16:00 (15) \cell +\pard\intbl\qc\fs16 346:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14MAR2013 / 21:00 (16) \cell +\pard\intbl\qc\fs16 06JUL2013 / 13:00 (130) \cell +\pard\intbl\qc\fs16 2728:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1368 \cell +\pard\intbl\qc\fs16 88 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23OCT2013 / 21:00 (1) \cell +\pard\intbl\qc\fs16 06NOV2013 / 05:00 (15) \cell +\pard\intbl\qc\fs16 320:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 07NOV2013 / 09:00 (16) \cell +\pard\intbl\qc\fs16 09APR2014 / 00:00 (169) \cell +\pard\intbl\qc\fs16 3663:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10APR2014 / 02:00 (170) \cell +\pard\intbl\qc\fs16 24APR2014 / 19:00 (184) \cell +\pard\intbl\qc\fs16 353:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-711-1036 \cell +\pard\intbl\qc\fs16 70 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 29JUL2012 / 20:00 (1) \cell +\pard\intbl\qc\fs16 12AUG2012 / 13:00 (15) \cell +\pard\intbl\qc\fs16 329:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13AUG2012 / 15:00 (16) \cell +\pard\intbl\qc\fs16 13JAN2013 / 08:00 (169) \cell +\pard\intbl\qc\fs16 3665:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14JAN2013 / 23:00 (170) \cell +\pard\intbl\qc\fs16 10FEB2013 / 08:00 (197) \cell +\pard\intbl\qc\fs16 633:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1179 \cell +\pard\intbl\qc\fs16 64 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09AUG2013 / 03:00 (1) \cell +\pard\intbl\qc\fs16 24AUG2013 / 18:00 (16) \cell +\pard\intbl\qc\fs16 375:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Cystoscopy with lesion. Rtu pending \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25AUG2013 / 23:00 (17) \cell +\pard\intbl\qc\fs16 24JAN2014 / 12:00 (169) \cell +\pard\intbl\qc\fs16 3637:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25JAN2014 / 11:00 (170) \cell +\pard\intbl\qc\fs16 05FEB2014 / 22:00 (181) \cell +\pard\intbl\qc\fs16 275:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1256 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19SEP2012 / 14:00 (1) \cell +\pard\intbl\qc\fs16 03OCT2012 / 06:00 (15) \cell +\pard\intbl\qc\fs16 328:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 04OCT2012 / 11:00 (16) \cell +\pard\intbl\qc\fs16 09MAR2013 / 08:00 (172) \cell +\pard\intbl\qc\fs16 3741:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10MAR2013 / 01:00 (173) \cell +\pard\intbl\qc\fs16 25MAR2013 / 13:00 (188) \cell +\pard\intbl\qc\fs16 372:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1269 \cell +\pard\intbl\qc\fs16 73 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27JAN2014 / 18:00 (1) \cell +\pard\intbl\qc\fs16 10FEB2014 / 00:00 (15) \cell +\pard\intbl\qc\fs16 318:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11FEB2014 / 16:00 (16) \cell +\pard\intbl\qc\fs16 13JUL2014 / 19:00 (168) \cell +\pard\intbl\qc\fs16 3651:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14JUL2014 / 12:00 (169) \cell +\pard\intbl\qc\fs16 28JUL2014 / 19:00 (183) \cell +\pard\intbl\qc\fs16 343:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1035 \cell +\pard\intbl\qc\fs16 88 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17APR2014 / 07:00 (1) \cell +\pard\intbl\qc\fs16 01MAY2014 / 18:00 (15) \cell +\pard\intbl\qc\fs16 347:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02MAY2014 / 20:00 (16) \cell +\pard\intbl\qc\fs16 02OCT2014 / 17:00 (169) \cell +\pard\intbl\qc\fs16 3669:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03OCT2014 / 12:00 (170) \cell +\pard\intbl\qc\fs16 16OCT2014 / 01:00 (183) \cell +\pard\intbl\qc\fs16 301:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1375 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26FEB2013 / 02:00 (1) \cell +\pard\intbl\qc\fs16 19MAR2013 / 14:00 (22) \cell +\pard\intbl\qc\fs16 516:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20MAR2013 / 13:00 (23) \cell +\pard\intbl\qc\fs16 23AUG2013 / 18:00 (179) \cell +\pard\intbl\qc\fs16 3749:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24AUG2013 / 03:00 (180) \cell +\pard\intbl\qc\fs16 07SEP2013 / 22:00 (194) \cell +\pard\intbl\qc\fs16 355:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1155 \cell +\pard\intbl\qc\fs16 59 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13DEC2013 / 13:00 (1) \cell +\pard\intbl\qc\fs16 27DEC2013 / 09:00 (15) \cell +\pard\intbl\qc\fs16 332:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28DEC2013 / 16:00 (16) \cell +\pard\intbl\qc\fs16 25JAN2014 / 22:00 (44) \cell +\pard\intbl\qc\fs16 678:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1207 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18NOV2012 / 04:00 (1) \cell +\pard\intbl\qc\fs16 02DEC2012 / 14:00 (15) \cell +\pard\intbl\qc\fs16 346:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03DEC2012 / 13:00 (16) \cell +\pard\intbl\qc\fs16 05MAY2013 / 13:00 (169) \cell +\pard\intbl\qc\fs16 3672:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06MAY2013 / 02:00 (170) \cell +\pard\intbl\qc\fs16 27MAY2013 / 05:00 (191) \cell +\pard\intbl\qc\fs16 507:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1397 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03APR2013 / 17:00 (1) \cell +\pard\intbl\qc\fs16 18APR2013 / 09:00 (16) \cell +\pard\intbl\qc\fs16 352:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was reported. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19APR2013 / 14:00 (17) \cell +\pard\intbl\qc\fs16 18SEP2013 / 11:00 (169) \cell +\pard\intbl\qc\fs16 3645:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19SEP2013 / 17:00 (170) \cell +\pard\intbl\qc\fs16 02OCT2013 / 13:00 (183) \cell +\pard\intbl\qc\fs16 308:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1024 \cell +\pard\intbl\qc\fs16 87 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Fatigue, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09JUL2012 / 15:00 (1) \cell +\pard\intbl\qc\fs16 23JUL2012 / 02:00 (15) \cell +\pard\intbl\qc\fs16 323:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Patient's vacation \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24JUL2012 / 14:00 (16) \cell +\pard\intbl\qc\fs16 30DEC2012 / 14:00 (175) \cell +\pard\intbl\qc\fs16 3816:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 31DEC2012 / 16:00 (176) \cell +\pard\intbl\qc\fs16 20JAN2013 / 10:00 (196) \cell +\pard\intbl\qc\fs16 474:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1026 \cell +\pard\intbl\qc\fs16 73 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02APR2014 / 19:00 (1) \cell +\pard\intbl\qc\fs16 18APR2014 / 18:00 (17) \cell +\pard\intbl\qc\fs16 383:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19APR2014 / 22:00 (18) \cell +\pard\intbl\qc\fs16 27SEP2014 / 21:00 (179) \cell +\pard\intbl\qc\fs16 3863:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28SEP2014 / 06:00 (180) \cell +\pard\intbl\qc\fs16 16OCT2014 / 01:00 (198) \cell +\pard\intbl\qc\fs16 427:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1044 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Pqc \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27APR2013 / 17:00 (1) \cell +\pard\intbl\qc\fs16 10MAY2013 / 10:00 (14) \cell +\pard\intbl\qc\fs16 305:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11MAY2013 / 13:00 (15) \cell +\pard\intbl\qc\fs16 16OCT2013 / 10:00 (173) \cell +\pard\intbl\qc\fs16 3789:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Fatigue, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17OCT2013 / 20:00 (174) \cell +\pard\intbl\qc\fs16 03NOV2013 / 03:00 (191) \cell +\pard\intbl\qc\fs16 391:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1108 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12FEB2013 / 22:00 (1) \cell +\pard\intbl\qc\fs16 26FEB2013 / 18:00 (15) \cell +\pard\intbl\qc\fs16 332:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Pqc \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27FEB2013 / 10:00 (16) \cell +\pard\intbl\qc\fs16 02AUG2013 / 10:00 (172) \cell +\pard\intbl\qc\fs16 3744:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03AUG2013 / 20:00 (173) \cell +\pard\intbl\qc\fs16 10AUG2013 / 06:00 (180) \cell +\pard\intbl\qc\fs16 154:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1238 \cell -\pard\intbl\qc\fs16 69 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 15MAY2013 / 05:00 (1) \cell -\pard\intbl\qc\fs16 29MAY2013 / --:-- (15) \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 01-716-1160 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05APR2013 / 23:00 (1) \cell +\pard\intbl\qc\fs16 19APR2013 / 17:00 (15) \cell +\pard\intbl\qc\fs16 330:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 1800 mg \cell -\pard\intbl\qc\fs16 30MAY2013 / 16:00 (16) \cell -\pard\intbl\qc\fs16 06AUG2013 / --:-- (84) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Infusion aborted / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20APR2013 / 05:00 (16) \cell +\pard\intbl\qc\fs16 27SEP2013 / 06:00 (176) \cell +\pard\intbl\qc\fs16 3841:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-709-1309 \cell -\pard\intbl\qc\fs16 65 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 19JUN2013 / 13:00 (1) \cell -\pard\intbl\qc\fs16 01JUL2013 / --:-- (13) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28SEP2013 / 06:00 (177) \cell +\pard\intbl\qc\fs16 11OCT2013 / 23:00 (190) \cell +\pard\intbl\qc\fs16 329:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1177 \cell +\pard\intbl\qc\fs16 72 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02SEP2014 / 08:00 (1) \cell +\pard\intbl\qc\fs16 16SEP2014 / 12:00 (15) \cell +\pard\intbl\qc\fs16 340:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 02JUL2013 / 19:00 (14) \cell -\pard\intbl\qc\fs16 05DEC2013 / --:-- (170) \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17SEP2014 / 07:00 (16) \cell +\pard\intbl\qc\fs16 17FEB2015 / 18:00 (169) \cell +\pard\intbl\qc\fs16 3683:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 720 mg \cell -\pard\intbl\qc\fs16 06DEC2013 / 16:00 (171) \cell -\pard\intbl\qc\fs16 19DEC2013 / --:-- (184) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Infusion rate increased / N/A \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Diarrhoea, Anaemia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18FEB2015 / 13:00 (170) \cell +\pard\intbl\qc\fs16 05MAR2015 / 12:00 (185) \cell +\pard\intbl\qc\fs16 359:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-710-1006 \cell +\pard\intbl\qc\fs16 01-716-1308 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Personal reasons \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28AUG2013 / 20:00 (1) \cell +\pard\intbl\qc\fs16 12SEP2013 / 15:00 (16) \cell +\pard\intbl\qc\fs16 355:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Diarrhoea, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13SEP2013 / 18:00 (17) \cell +\pard\intbl\qc\fs16 07OCT2013 / 18:00 (41) \cell +\pard\intbl\qc\fs16 576:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1441 \cell +\pard\intbl\qc\fs16 85 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22JAN2014 / 23:00 (1) \cell +\pard\intbl\qc\fs16 06FEB2014 / 06:00 (16) \cell +\pard\intbl\qc\fs16 343:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 07FEB2014 / 08:00 (17) \cell +\pard\intbl\qc\fs16 08JUL2014 / 17:00 (168) \cell +\pard\intbl\qc\fs16 3633:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Personal reasons \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09JUL2014 / 07:00 (169) \cell +\pard\intbl\qc\fs16 22JUL2014 / 13:00 (182) \cell +\pard\intbl\qc\fs16 318:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1201 \cell +\pard\intbl\qc\fs16 85 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19DEC2013 / 02:00 (1) \cell +\pard\intbl\qc\fs16 03JAN2014 / 00:00 (16) \cell +\pard\intbl\qc\fs16 358:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 04JAN2014 / 14:00 (17) \cell +\pard\intbl\qc\fs16 21FEB2014 / 04:00 (65) \cell +\pard\intbl\qc\fs16 1142:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1344 \cell +\pard\intbl\qc\fs16 64 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11JAN2014 / 12:00 (1) \cell +\pard\intbl\qc\fs16 24JAN2014 / 17:00 (14) \cell +\pard\intbl\qc\fs16 317:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25JAN2014 / 21:00 (15) \cell +\pard\intbl\qc\fs16 14MAR2014 / 10:00 (63) \cell +\pard\intbl\qc\fs16 1141:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1139 \cell \pard\intbl\qc\fs16 77 / Male / White \cell -\pard\intbl\qc\fs16 BASELINE \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 10FEB2013 / 07:00 (1) \cell -\pard\intbl\qc\fs16 22FEB2013 / --:-- (13) \cell -\pard\intbl\qc\fs16 Dose re-escalated / N/A \cell -\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / N/A \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19MAY2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 02JUN2013 / 10:00 (15) \cell +\pard\intbl\qc\fs16 332:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 2 \cell -\pard\intbl\qc\fs16 15 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 3600 mg \cell -\pard\intbl\qc\fs16 23FEB2013 / 02:00 (14) \cell -\pard\intbl\qc\fs16 27JUL2013 / --:-- (168) \cell -\pard\intbl\qc\fs16 Study drug permanently discontinued / N/A \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03JUN2013 / 02:00 (16) \cell +\pard\intbl\qc\fs16 03NOV2013 / 06:00 (169) \cell +\pard\intbl\qc\fs16 3676:00 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3254 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4100 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4546 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5526 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6195 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7309 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8423 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11587 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 WEEK 24 \cell -\pard\intbl\qc\fs16 7.5 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 480 mg \cell -\pard\intbl\qc\fs16 28JUL2013 / 05:00 (169) \cell -\pard\intbl\qc\fs16 09AUG2013 / --:-- (181) \cell -\pard\intbl\qc\fs16 Infusion delayed within the cycle / N/A \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 04NOV2013 / 21:00 (170) \cell +\pard\intbl\qc\fs16 17NOV2013 / 17:00 (183) \cell +\pard\intbl\qc\fs16 308:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1150 \cell +\pard\intbl\qc\fs16 73 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19JAN2013 / 14:00 (1) \cell +\pard\intbl\qc\fs16 02FEB2013 / 02:00 (15) \cell +\pard\intbl\qc\fs16 324:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03FEB2013 / 16:00 (16) \cell +\pard\intbl\qc\fs16 07JUL2013 / 19:00 (170) \cell +\pard\intbl\qc\fs16 3699:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 200 mg \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08JUL2013 / 16:00 (171) \cell +\pard\intbl\qc\fs16 29JUL2013 / 23:00 (192) \cell +\pard\intbl\qc\fs16 511:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1172 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 100 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 21SEP2013 / 10:00 (1) \cell +\pard\intbl\qc\fs16 05OCT2013 / 11:00 (15) \cell +\pard\intbl\qc\fs16 337:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06OCT2013 / 20:00 (16) \cell +\pard\intbl\qc\fs16 29NOV2013 / 20:00 (70) \cell +\pard\intbl\qc\fs16 1296:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1355 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 300 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Anaemia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28FEB2013 / 11:00 (1) \cell +\pard\intbl\qc\fs16 16MAR2013 / 19:00 (17) \cell +\pard\intbl\qc\fs16 392:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 250 mg \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17MAR2013 / 23:00 (18) \cell +\pard\intbl\qc\fs16 15AUG2013 / 01:00 (169) \cell +\pard\intbl\qc\fs16 3602:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx754 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1220 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2440 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3086 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4270 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4916 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6064 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6889 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8073 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8970 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9508 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10333 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11230 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12127 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 Dose re-escalated / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 150 mg \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16AUG2013 / 06:00 (170) \cell +\pard\intbl\qc\fs16 29AUG2013 / 01:00 (183) \cell +\pard\intbl\qc\fs16 307:00 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3254 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4100 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4546 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5526 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6195 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7309 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8423 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11587 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx754 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1220 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1830 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2440 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3086 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4270 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4916 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6064 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6889 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8073 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx8970 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9508 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10333 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11230 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12127 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2882,22 +21414,30 @@ \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3254 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4100 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4546 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5526 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6195 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7309 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8423 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11587 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx754 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1220 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1830 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2440 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3086 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4270 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4916 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6064 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6889 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8073 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx8970 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9508 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10333 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11230 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12127 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell @@ -2910,6 +21450,10 @@ \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell \row } \par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} diff --git a/tests/testthat/_snaps/lsiex04/lsiex04.rtf b/tests/testthat/_snaps/lsiex04/lsiex04.rtf new file mode 100644 index 00000000..fbe10279 --- /dev/null +++ b/tests/testthat/_snaps/lsiex04/lsiex04.rtf @@ -0,0 +1,19076 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx887 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1435 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2152 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2870 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3629 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4389 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5781 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6541 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7891 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9283 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10212 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11182 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12153 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 LSIEX04:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx887 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx1435 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2152 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2870 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx3629 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx4389 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5781 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx6541 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7891 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx9283 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10212 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11182 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12153 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \brdrb\brdrs \keepn\trhdr Prescribed \cell +\pard\intbl\qc\fs16 \brdrb\brdrs \keepn\trhdr Prescribed \cell +\pard\intbl\qc\fs16 \brdrb\brdrs \keepn\trhdr Prior to Injection Start \cell +\pard\intbl\qc\fs16 \brdrb\brdrs \keepn\trhdr Prior to Injection Start \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \brdrb\brdrs \keepn\trhdr During Injection \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\pard\intbl\qc\fs16 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx887 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \keepn\trhdr Treatment Group \cell +\pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell +\pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell +\pard\intbl\qc\fs16 \keepn\trhdr Visit \cell +\pard\intbl\qc\fs16 \keepn\trhdr Dose [Level] (unit) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Injection Volume (mL) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Action Taken\super a\nosupersub / Reason \cell +\pard\intbl\qc\fs16 \keepn\trhdr Schedule Change New Dosing Frequency \cell +\pard\intbl\qc\fs16 \keepn\trhdr Dose Delayed? / Reason \cell +\pard\intbl\qc\fs16 \keepn\trhdr Action Taken / Reason \cell +\pard\intbl\qc\fs16 \keepn\trhdr Volume of Investigation Product Injected (mL) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Actual Dose Administered (unit) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Start Date (Study Day\super b\nosupersub ) \cell +\pard\intbl\qc\fs16 \keepn\trhdr Start Time / End Time \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 18MAR2014 (1) \cell +\pard\intbl\qc\fs16 15:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1097 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01JAN2014 (1) \cell +\pard\intbl\qc\fs16 07:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16JAN2014 (16) \cell +\pard\intbl\qc\fs16 15:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JUN2014 (170) \cell +\pard\intbl\qc\fs16 18:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Nausea, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07SEP2012 (1) \cell +\pard\intbl\qc\fs16 11:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Due to personal schedule \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 30NOV2012 (1) \cell +\pard\intbl\qc\fs16 17:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14DEC2012 (15) \cell +\pard\intbl\qc\fs16 17:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05DEC2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15FEB2013 (1) \cell +\pard\intbl\qc\fs16 10:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03MAR2013 (17) \cell +\pard\intbl\qc\fs16 15:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22JUL2012 (1) \cell +\pard\intbl\qc\fs16 00:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08AUG2012 (18) \cell +\pard\intbl\qc\fs16 10:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12JAN2013 (175) \cell +\pard\intbl\qc\fs16 03:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15NOV2012 (1) \cell +\pard\intbl\qc\fs16 05:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29NOV2012 (15) \cell +\pard\intbl\qc\fs16 19:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 67 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24MAR2013 (1) \cell +\pard\intbl\qc\fs16 06:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11APR2013 (19) \cell +\pard\intbl\qc\fs16 19:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22MAY2014 (1) \cell +\pard\intbl\qc\fs16 13:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Progression \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06JUN2014 (16) \cell +\pard\intbl\qc\fs16 09:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07NOV2014 (170) \cell +\pard\intbl\qc\fs16 07:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Headache, Pyrexia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02OCT2012 (1) \cell +\pard\intbl\qc\fs16 03:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17OCT2012 (16) \cell +\pard\intbl\qc\fs16 18:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20MAR2013 (170) \cell +\pard\intbl\qc\fs16 01:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 51 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05JAN2013 (1) \cell +\pard\intbl\qc\fs16 22:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Tar-200 did not take the pretzel shape inside the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JAN2013 (15) \cell +\pard\intbl\qc\fs16 08:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 67 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Rash, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31JUL2013 (1) \cell +\pard\intbl\qc\fs16 11:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1429 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19MAR2013 (1) \cell +\pard\intbl\qc\fs16 14:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03APR2013 (16) \cell +\pard\intbl\qc\fs16 02:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1442 \cell +\pard\intbl\qc\fs16 57 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26OCT2013 (1) \cell +\pard\intbl\qc\fs16 09:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10NOV2013 (16) \cell +\pard\intbl\qc\fs16 05:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Fatigue, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 18APR2014 (175) \cell +\pard\intbl\qc\fs16 11:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-702-1082 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26JUL2013 (1) \cell +\pard\intbl\qc\fs16 13:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09AUG2013 (15) \cell +\pard\intbl\qc\fs16 13:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1086 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02SEP2012 (1) \cell +\pard\intbl\qc\fs16 08:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17SEP2012 (16) \cell +\pard\intbl\qc\fs16 10:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20FEB2013 (1) \cell +\pard\intbl\qc\fs16 17:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11MAR2013 (20) \cell +\pard\intbl\qc\fs16 02:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17OCT2013 (1) \cell +\pard\intbl\qc\fs16 06:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01NOV2013 (16) \cell +\pard\intbl\qc\fs16 22:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 76 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16JUN2013 (1) \cell +\pard\intbl\qc\fs16 07:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1279 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13MAY2013 (1) \cell +\pard\intbl\qc\fs16 00:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1379 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22SEP2013 (1) \cell +\pard\intbl\qc\fs16 02:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Suspicion of disease progression \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08OCT2013 (17) \cell +\pard\intbl\qc\fs16 12:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09MAR2014 (169) \cell +\pard\intbl\qc\fs16 18:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1403 \cell +\pard\intbl\qc\fs16 67 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12DEC2012 (1) \cell +\pard\intbl\qc\fs16 15:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1009 \cell +\pard\intbl\qc\fs16 83 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27AUG2013 (1) \cell +\pard\intbl\qc\fs16 16:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15SEP2013 (20) \cell +\pard\intbl\qc\fs16 22:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27SEP2013 (1) \cell +\pard\intbl\qc\fs16 11:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12OCT2013 (16) \cell +\pard\intbl\qc\fs16 08:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1114 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23JAN2013 (1) \cell +\pard\intbl\qc\fs16 16:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04FEB2013 (13) \cell +\pard\intbl\qc\fs16 20:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02DEC2013 (1) \cell +\pard\intbl\qc\fs16 05:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16DEC2013 (15) \cell +\pard\intbl\qc\fs16 08:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1135 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31OCT2013 (1) \cell +\pard\intbl\qc\fs16 22:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15NOV2013 (16) \cell +\pard\intbl\qc\fs16 20:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02MAY2014 (184) \cell +\pard\intbl\qc\fs16 19:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19NOV2012 (1) \cell +\pard\intbl\qc\fs16 21:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04DEC2012 (16) \cell +\pard\intbl\qc\fs16 05:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14MAY2013 (177) \cell +\pard\intbl\qc\fs16 14:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 68 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08JUL2013 (1) \cell +\pard\intbl\qc\fs16 06:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24JUL2013 (17) \cell +\pard\intbl\qc\fs16 09:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23APR2014 (1) \cell +\pard\intbl\qc\fs16 05:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08MAY2014 (16) \cell +\pard\intbl\qc\fs16 12:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27NOV2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19DEC2013 (23) \cell +\pard\intbl\qc\fs16 17:00 / UTC \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 87 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Pqc \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16SEP2013 (1) \cell +\pard\intbl\qc\fs16 09:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1292 \cell +\pard\intbl\qc\fs16 60 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14OCT2013 (1) \cell +\pard\intbl\qc\fs16 22:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 30OCT2013 (17) \cell +\pard\intbl\qc\fs16 00:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29APR2014 (198) \cell +\pard\intbl\qc\fs16 18:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1382 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Bladder mapping performed on 20 nov 2023 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13MAY2013 (1) \cell +\pard\intbl\qc\fs16 15:00 / UTC \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1393 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07SEP2012 (1) \cell +\pard\intbl\qc\fs16 07:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28SEP2012 (22) \cell +\pard\intbl\qc\fs16 13:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1431 \cell +\pard\intbl\qc\fs16 68 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23JUN2013 (1) \cell +\pard\intbl\qc\fs16 15:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08JUL2013 (16) \cell +\pard\intbl\qc\fs16 21:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06DEC2013 (167) \cell +\pard\intbl\qc\fs16 04:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-706-1384 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15SEP2012 (1) \cell +\pard\intbl\qc\fs16 13:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20DEC2013 (1) \cell +\pard\intbl\qc\fs16 08:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1019 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20DEC2013 (1) \cell +\pard\intbl\qc\fs16 00:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1032 \cell +\pard\intbl\qc\fs16 62 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09FEB2013 (1) \cell +\pard\intbl\qc\fs16 22:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24FEB2013 (16) \cell +\pard\intbl\qc\fs16 19:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1084 \cell +\pard\intbl\qc\fs16 73 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09MAY2013 (1) \cell +\pard\intbl\qc\fs16 05:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24MAY2013 (16) \cell +\pard\intbl\qc\fs16 20:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: The dose delayed due to turb performed 10-nov-2023 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29OCT2013 (174) \cell +\pard\intbl\qc\fs16 11:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1213 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09FEB2013 (1) \cell +\pard\intbl\qc\fs16 03:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 21SEP2013 (1) \cell +\pard\intbl\qc\fs16 14:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06FEB2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22FEB2013 (17) \cell +\pard\intbl\qc\fs16 01:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 61 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25JAN2013 (1) \cell +\pard\intbl\qc\fs16 11:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09FEB2013 (16) \cell +\pard\intbl\qc\fs16 00:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1348 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05AUG2013 (1) \cell +\pard\intbl\qc\fs16 04:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20AUG2013 (16) \cell +\pard\intbl\qc\fs16 07:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04FEB2014 (184) \cell +\pard\intbl\qc\fs16 14:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1353 \cell +\pard\intbl\qc\fs16 87 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04JUL2013 (1) \cell +\pard\intbl\qc\fs16 13:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Pt had his 24w turb on 22th of december so tar was removed at that time \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JUL2013 (16) \cell +\pard\intbl\qc\fs16 01:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1372 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12APR2013 (1) \cell +\pard\intbl\qc\fs16 03:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1428 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Rash, Pyrexia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09NOV2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24NOV2013 (16) \cell +\pard\intbl\qc\fs16 12:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1007 \cell +\pard\intbl\qc\fs16 54 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31JUL2012 (1) \cell +\pard\intbl\qc\fs16 19:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19AUG2012 (20) \cell +\pard\intbl\qc\fs16 19:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1020 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01DEC2012 (1) \cell +\pard\intbl\qc\fs16 19:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16DEC2012 (16) \cell +\pard\intbl\qc\fs16 21:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19MAY2013 (170) \cell +\pard\intbl\qc\fs16 21:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1081 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Urine culture not disponible \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 18JAN2014 (1) \cell +\pard\intbl\qc\fs16 02:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02FEB2014 (16) \cell +\pard\intbl\qc\fs16 05:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1102 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15JAN2013 (1) \cell +\pard\intbl\qc\fs16 21:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01FEB2013 (18) \cell +\pard\intbl\qc\fs16 17:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04MAR2013 (1) \cell +\pard\intbl\qc\fs16 04:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Urine culture not disponible \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20MAR2013 (17) \cell +\pard\intbl\qc\fs16 16:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1285 \cell +\pard\intbl\qc\fs16 87 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Rash, Oedema peripheral) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24MAR2013 (1) \cell +\pard\intbl\qc\fs16 01:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Vomiting, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09APR2013 (17) \cell +\pard\intbl\qc\fs16 03:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1326 \cell +\pard\intbl\qc\fs16 75 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05APR2013 (1) \cell +\pard\intbl\qc\fs16 16:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19APR2013 (15) \cell +\pard\intbl\qc\fs16 21:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 21SEP2013 (170) \cell +\pard\intbl\qc\fs16 00:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1329 \cell +\pard\intbl\qc\fs16 70 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15AUG2013 (1) \cell +\pard\intbl\qc\fs16 13:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1424 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03MAR2013 (1) \cell +\pard\intbl\qc\fs16 14:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1002 \cell +\pard\intbl\qc\fs16 88 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14JAN2014 (1) \cell +\pard\intbl\qc\fs16 18:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1045 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03JUN2013 (1) \cell +\pard\intbl\qc\fs16 14:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 18JUN2013 (16) \cell +\pard\intbl\qc\fs16 22:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1053 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26DEC2012 (1) \cell +\pard\intbl\qc\fs16 16:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10JAN2013 (16) \cell +\pard\intbl\qc\fs16 10:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1154 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29MAR2014 (1) \cell +\pard\intbl\qc\fs16 04:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13APR2014 (16) \cell +\pard\intbl\qc\fs16 21:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1166 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 30NOV2012 (1) \cell +\pard\intbl\qc\fs16 15:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Drug was never administered because the subject dropped out prior to first dose \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15DEC2012 (16) \cell +\pard\intbl\qc\fs16 22:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1235 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26SEP2012 (1) \cell +\pard\intbl\qc\fs16 06:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11OCT2012 (16) \cell +\pard\intbl\qc\fs16 18:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14MAR2013 (170) \cell +\pard\intbl\qc\fs16 12:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1270 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12FEB2014 (1) \cell +\pard\intbl\qc\fs16 18:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1300 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15DEC2012 (1) \cell +\pard\intbl\qc\fs16 01:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Due to personal schedule \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31DEC2012 (17) \cell +\pard\intbl\qc\fs16 00:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1358 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17SEP2012 (1) \cell +\pard\intbl\qc\fs16 05:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02OCT2012 (16) \cell +\pard\intbl\qc\fs16 19:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1385 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29OCT2012 (1) \cell +\pard\intbl\qc\fs16 09:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13NOV2012 (16) \cell +\pard\intbl\qc\fs16 16:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-711-1143 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03APR2013 (1) \cell +\pard\intbl\qc\fs16 00:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 18APR2013 (16) \cell +\pard\intbl\qc\fs16 02:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-711-1433 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27JAN2013 (1) \cell +\pard\intbl\qc\fs16 15:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1043 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15SEP2013 (1) \cell +\pard\intbl\qc\fs16 09:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Suspicion of disease progression \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01OCT2013 (17) \cell +\pard\intbl\qc\fs16 03:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01MAR2014 (168) \cell +\pard\intbl\qc\fs16 20:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1073 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache, Oedema peripheral) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 30MAR2014 (1) \cell +\pard\intbl\qc\fs16 07:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Headache, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15APR2014 (17) \cell +\pard\intbl\qc\fs16 16:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Due to personal schedule \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22SEP2014 (177) \cell +\pard\intbl\qc\fs16 15:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1448 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JAN2014 (1) \cell +\pard\intbl\qc\fs16 13:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02FEB2014 (15) \cell +\pard\intbl\qc\fs16 08:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1068 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08AUG2013 (1) \cell +\pard\intbl\qc\fs16 10:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23AUG2013 (16) \cell +\pard\intbl\qc\fs16 04:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1195 \cell +\pard\intbl\qc\fs16 75 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26APR2013 (1) \cell +\pard\intbl\qc\fs16 18:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10MAY2013 (15) \cell +\pard\intbl\qc\fs16 13:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11OCT2013 (169) \cell +\pard\intbl\qc\fs16 23:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1425 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15AUG2013 (1) \cell +\pard\intbl\qc\fs16 04:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1085 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16FEB2013 (1) \cell +\pard\intbl\qc\fs16 16:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05MAR2013 (18) \cell +\pard\intbl\qc\fs16 01:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05AUG2013 (171) \cell +\pard\intbl\qc\fs16 16:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1107 \cell +\pard\intbl\qc\fs16 65 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26FEB2013 (1) \cell +\pard\intbl\qc\fs16 09:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13MAR2013 (16) \cell +\pard\intbl\qc\fs16 03:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1405 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Rash, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06JUL2013 (1) \cell +\pard\intbl\qc\fs16 09:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1030 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Rash, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28DEC2013 (1) \cell +\pard\intbl\qc\fs16 15:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1063 \cell +\pard\intbl\qc\fs16 80 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09MAY2013 (1) \cell +\pard\intbl\qc\fs16 10:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24MAY2013 (16) \cell +\pard\intbl\qc\fs16 11:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1094 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19DEC2012 (1) \cell +\pard\intbl\qc\fs16 12:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07JAN2013 (20) \cell +\pard\intbl\qc\fs16 00:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1103 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20MAR2014 (1) \cell +\pard\intbl\qc\fs16 11:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06APR2014 (18) \cell +\pard\intbl\qc\fs16 00:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31AUG2014 (165) \cell +\pard\intbl\qc\fs16 14:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1151 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Bladder mapping performed on 20 nov 2023 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01FEB2013 (1) \cell +\pard\intbl\qc\fs16 04:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16FEB2013 (16) \cell +\pard\intbl\qc\fs16 02:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1157 \cell +\pard\intbl\qc\fs16 85 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02OCT2013 (1) \cell +\pard\intbl\qc\fs16 01:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17OCT2013 (16) \cell +\pard\intbl\qc\fs16 11:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Pt had his 24w turb on 22th of december so tar was removed at that time \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27MAR2014 (177) \cell +\pard\intbl\qc\fs16 19:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1167 \cell +\pard\intbl\qc\fs16 68 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08OCT2012 (1) \cell +\pard\intbl\qc\fs16 03:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 30OCT2012 (23) \cell +\pard\intbl\qc\fs16 09:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25MAR2013 (169) \cell +\pard\intbl\qc\fs16 10:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1298 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08APR2013 (1) \cell +\pard\intbl\qc\fs16 21:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23APR2013 (16) \cell +\pard\intbl\qc\fs16 05:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1311 \cell +\pard\intbl\qc\fs16 78 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14MAY2014 (1) \cell +\pard\intbl\qc\fs16 22:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29MAY2014 (16) \cell +\pard\intbl\qc\fs16 14:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1004 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14JAN2014 (1) \cell +\pard\intbl\qc\fs16 11:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29JAN2014 (16) \cell +\pard\intbl\qc\fs16 10:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02JUL2014 (170) \cell +\pard\intbl\qc\fs16 05:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1446 \cell +\pard\intbl\qc\fs16 75 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01SEP2013 (1) \cell +\pard\intbl\qc\fs16 16:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17SEP2013 (17) \cell +\pard\intbl\qc\fs16 09:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17FEB2014 (170) \cell +\pard\intbl\qc\fs16 23:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1066 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07JUL2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1079 \cell +\pard\intbl\qc\fs16 67 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19SEP2012 (1) \cell +\pard\intbl\qc\fs16 13:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04OCT2012 (16) \cell +\pard\intbl\qc\fs16 22:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1170 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Nausea, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Nausea, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16SEP2013 (1) \cell +\pard\intbl\qc\fs16 02:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 30SEP2013 (15) \cell +\pard\intbl\qc\fs16 10:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1250 \cell +\pard\intbl\qc\fs16 82 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 21SEP2013 (1) \cell +\pard\intbl\qc\fs16 06:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04OCT2013 (14) \cell +\pard\intbl\qc\fs16 13:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1254 \cell +\pard\intbl\qc\fs16 78 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Sheet could not into the bladder \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10JUL2013 (1) \cell +\pard\intbl\qc\fs16 09:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26JUL2013 (17) \cell +\pard\intbl\qc\fs16 17:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27DEC2013 (171) \cell +\pard\intbl\qc\fs16 17:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell +\pard\intbl\qc\fs16 01-701-1028 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Bladder mapping performed on 20 nov 2023 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JUL2013 (1) \cell +\pard\intbl\qc\fs16 08:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 02AUG2013 (15) \cell +\pard\intbl\qc\fs16 13:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07JAN2014 (173) \cell +\pard\intbl\qc\fs16 14:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1034 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01JUL2014 (1) \cell +\pard\intbl\qc\fs16 12:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16JUL2014 (16) \cell +\pard\intbl\qc\fs16 16:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18DEC2014 (171) \cell +\pard\intbl\qc\fs16 08:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1133 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28OCT2012 (1) \cell +\pard\intbl\qc\fs16 07:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 13NOV2012 (17) \cell +\pard\intbl\qc\fs16 17:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19APR2013 (174) \cell +\pard\intbl\qc\fs16 02:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1146 \cell +\pard\intbl\qc\fs16 75 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20MAY2013 (1) \cell +\pard\intbl\qc\fs16 16:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 04JUN2013 (16) \cell +\pard\intbl\qc\fs16 06:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1148 \cell +\pard\intbl\qc\fs16 57 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23AUG2013 (1) \cell +\pard\intbl\qc\fs16 14:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 06SEP2013 (15) \cell +\pard\intbl\qc\fs16 20:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09FEB2014 (171) \cell +\pard\intbl\qc\fs16 12:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1180 \cell +\pard\intbl\qc\fs16 56 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12FEB2013 (1) \cell +\pard\intbl\qc\fs16 20:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 26FEB2013 (15) \cell +\pard\intbl\qc\fs16 17:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1239 \cell +\pard\intbl\qc\fs16 56 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11JAN2014 (1) \cell +\pard\intbl\qc\fs16 20:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 26JAN2014 (16) \cell +\pard\intbl\qc\fs16 00:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28JUN2014 (169) \cell +\pard\intbl\qc\fs16 23:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1275 \cell +\pard\intbl\qc\fs16 61 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07FEB2014 (1) \cell +\pard\intbl\qc\fs16 23:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 23FEB2014 (17) \cell +\pard\intbl\qc\fs16 04:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1287 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25JAN2014 (1) \cell +\pard\intbl\qc\fs16 00:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 12FEB2014 (19) \cell +\pard\intbl\qc\fs16 12:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13JUL2014 (170) \cell +\pard\intbl\qc\fs16 03:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1302 \cell +\pard\intbl\qc\fs16 61 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29AUG2013 (1) \cell +\pard\intbl\qc\fs16 13:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 16SEP2013 (19) \cell +\pard\intbl\qc\fs16 07:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1383 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Rash, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04FEB2013 (1) \cell +\pard\intbl\qc\fs16 07:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 20FEB2013 (17) \cell +\pard\intbl\qc\fs16 15:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31JUL2013 (178) \cell +\pard\intbl\qc\fs16 15:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1444 \cell +\pard\intbl\qc\fs16 63 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Suspicion of disease progression \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05JAN2013 (1) \cell +\pard\intbl\qc\fs16 18:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Insertion failed \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 19JAN2013 (15) \cell +\pard\intbl\qc\fs16 13:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1076 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25OCT2013 (1) \cell +\pard\intbl\qc\fs16 15:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 07NOV2013 (14) \cell +\pard\intbl\qc\fs16 20:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1258 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20JUL2012 (1) \cell +\pard\intbl\qc\fs16 03:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 02AUG2012 (14) \cell +\pard\intbl\qc\fs16 20:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01JAN2013 (166) \cell +\pard\intbl\qc\fs16 06:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1295 \cell +\pard\intbl\qc\fs16 88 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 21NOV2013 (1) \cell +\pard\intbl\qc\fs16 20:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 06DEC2013 (16) \cell +\pard\intbl\qc\fs16 14:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1335 \cell +\pard\intbl\qc\fs16 67 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17MAR2014 (1) \cell +\pard\intbl\qc\fs16 00:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 01APR2014 (16) \cell +\pard\intbl\qc\fs16 04:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1439 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12MAR2014 (1) \cell +\pard\intbl\qc\fs16 10:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 27MAR2014 (16) \cell +\pard\intbl\qc\fs16 16:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29AUG2014 (171) \cell +\pard\intbl\qc\fs16 13:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1008 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13JAN2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 29JAN2013 (17) \cell +\pard\intbl\qc\fs16 04:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1017 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06OCT2013 (1) \cell +\pard\intbl\qc\fs16 08:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 20OCT2013 (15) \cell +\pard\intbl\qc\fs16 22:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1065 \cell +\pard\intbl\qc\fs16 75 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24OCT2013 (1) \cell +\pard\intbl\qc\fs16 21:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 08NOV2013 (16) \cell +\pard\intbl\qc\fs16 02:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1074 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22JAN2014 (1) \cell +\pard\intbl\qc\fs16 20:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 10FEB2014 (20) \cell +\pard\intbl\qc\fs16 11:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1093 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Nausea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15MAR2013 (1) \cell +\pard\intbl\qc\fs16 08:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 31MAR2013 (17) \cell +\pard\intbl\qc\fs16 20:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1241 \cell +\pard\intbl\qc\fs16 86 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25AUG2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 06SEP2013 (13) \cell +\pard\intbl\qc\fs16 17:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1266 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13OCT2013 (1) \cell +\pard\intbl\qc\fs16 22:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 28OCT2013 (16) \cell +\pard\intbl\qc\fs16 17:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1332 \cell +\pard\intbl\qc\fs16 80 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09DEC2013 (1) \cell +\pard\intbl\qc\fs16 15:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 24DEC2013 (16) \cell +\pard\intbl\qc\fs16 23:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1280 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17JAN2014 (1) \cell +\pard\intbl\qc\fs16 04:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 01FEB2014 (16) \cell +\pard\intbl\qc\fs16 09:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12JUL2014 (177) \cell +\pard\intbl\qc\fs16 16:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1281 \cell +\pard\intbl\qc\fs16 73 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28NOV2013 (1) \cell +\pard\intbl\qc\fs16 22:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 16DEC2013 (19) \cell +\pard\intbl\qc\fs16 19:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1303 \cell +\pard\intbl\qc\fs16 72 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16DEC2013 (1) \cell +\pard\intbl\qc\fs16 03:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Pqc was reported. \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 31DEC2013 (16) \cell +\pard\intbl\qc\fs16 17:00 / UTC \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1310 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02NOV2013 (1) \cell +\pard\intbl\qc\fs16 16:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 23NOV2013 (22) \cell +\pard\intbl\qc\fs16 07:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1377 \cell +\pard\intbl\qc\fs16 63 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04JAN2014 (1) \cell +\pard\intbl\qc\fs16 20:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 26JAN2014 (23) \cell +\pard\intbl\qc\fs16 09:00 / UTC \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-706-1049 \cell +\pard\intbl\qc\fs16 60 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14MAY2013 (1) \cell +\pard\intbl\qc\fs16 10:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 29MAY2013 (16) \cell +\pard\intbl\qc\fs16 19:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1178 \cell +\pard\intbl\qc\fs16 77 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29DEC2013 (1) \cell +\pard\intbl\qc\fs16 03:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 19JAN2014 (22) \cell +\pard\intbl\qc\fs16 05:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1216 \cell +\pard\intbl\qc\fs16 78 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24OCT2012 (1) \cell +\pard\intbl\qc\fs16 22:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Vomiting, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Vomiting, Neutropenia) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 09NOV2012 (17) \cell +\pard\intbl\qc\fs16 10:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1336 \cell +\pard\intbl\qc\fs16 73 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07DEC2012 (1) \cell +\pard\intbl\qc\fs16 18:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 22DEC2012 (16) \cell +\pard\intbl\qc\fs16 11:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23MAY2013 (168) \cell +\pard\intbl\qc\fs16 01:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1347 \cell +\pard\intbl\qc\fs16 61 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Fatigue, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20APR2013 (1) \cell +\pard\intbl\qc\fs16 14:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 05MAY2013 (16) \cell +\pard\intbl\qc\fs16 12:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1406 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Cystoscopy with lesion. Rtu pending \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26DEC2013 (1) \cell +\pard\intbl\qc\fs16 21:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 10JAN2014 (16) \cell +\pard\intbl\qc\fs16 06:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17JUN2014 (174) \cell +\pard\intbl\qc\fs16 22:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1029 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25DEC2012 (1) \cell +\pard\intbl\qc\fs16 23:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Vomiting, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 10JAN2013 (17) \cell +\pard\intbl\qc\fs16 12:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 13JUN2013 (171) \cell +\pard\intbl\qc\fs16 09:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1099 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 25OCT2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 13NOV2013 (20) \cell +\pard\intbl\qc\fs16 21:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 12APR2014 (170) \cell +\pard\intbl\qc\fs16 13:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1168 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Pt had his 24w turb on 22th of december so tar was removed at that time \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02AUG2013 (1) \cell +\pard\intbl\qc\fs16 04:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 18AUG2013 (17) \cell +\pard\intbl\qc\fs16 23:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1238 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15MAY2013 (1) \cell +\pard\intbl\qc\fs16 08:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 30MAY2013 (16) \cell +\pard\intbl\qc\fs16 14:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1309 \cell +\pard\intbl\qc\fs16 65 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JUN2013 (1) \cell +\pard\intbl\qc\fs16 01:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 02JUL2013 (14) \cell +\pard\intbl\qc\fs16 09:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 06DEC2013 (171) \cell +\pard\intbl\qc\fs16 17:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1006 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10FEB2013 (1) \cell +\pard\intbl\qc\fs16 20:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 23FEB2013 (14) \cell +\pard\intbl\qc\fs16 14:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Insertion failed \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28JUL2013 (169) \cell +\pard\intbl\qc\fs16 17:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1021 \cell +\pard\intbl\qc\fs16 79 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27SEP2013 (1) \cell +\pard\intbl\qc\fs16 07:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Pyrexia) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 12OCT2013 (16) \cell +\pard\intbl\qc\fs16 17:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1070 \cell +\pard\intbl\qc\fs16 85 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Fatigue, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08SEP2012 (1) \cell +\pard\intbl\qc\fs16 03:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 23SEP2012 (16) \cell +\pard\intbl\qc\fs16 13:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1137 \cell +\pard\intbl\qc\fs16 79 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Diarrhoea, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11OCT2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 26OCT2013 (16) \cell +\pard\intbl\qc\fs16 23:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1142 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 02OCT2012 (1) \cell +\pard\intbl\qc\fs16 19:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Insertion failed \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 17OCT2012 (16) \cell +\pard\intbl\qc\fs16 07:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1187 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 10NOV2012 (1) \cell +\pard\intbl\qc\fs16 18:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 25NOV2012 (16) \cell +\pard\intbl\qc\fs16 14:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29APR2013 (171) \cell +\pard\intbl\qc\fs16 06:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1249 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28DEC2013 (1) \cell +\pard\intbl\qc\fs16 12:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 12JAN2014 (16) \cell +\pard\intbl\qc\fs16 23:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15JUN2014 (170) \cell +\pard\intbl\qc\fs16 13:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1278 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Pqc was reported. \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24DEC2012 (1) \cell +\pard\intbl\qc\fs16 01:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 08JAN2013 (16) \cell +\pard\intbl\qc\fs16 19:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1354 \cell +\pard\intbl\qc\fs16 73 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11NOV2012 (1) \cell +\pard\intbl\qc\fs16 01:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 26NOV2012 (16) \cell +\pard\intbl\qc\fs16 21:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22APR2013 (163) \cell +\pard\intbl\qc\fs16 07:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1408 \cell +\pard\intbl\qc\fs16 80 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05JAN2013 (1) \cell +\pard\intbl\qc\fs16 08:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 25JAN2013 (21) \cell +\pard\intbl\qc\fs16 14:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Fatigue, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 29JUN2013 (176) \cell +\pard\intbl\qc\fs16 20:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-711-1012 \cell +\pard\intbl\qc\fs16 67 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Nausea, Anaemia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 03APR2013 (1) \cell +\pard\intbl\qc\fs16 16:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 18APR2013 (16) \cell +\pard\intbl\qc\fs16 17:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1106 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Pyrexia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31OCT2012 (1) \cell +\pard\intbl\qc\fs16 21:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 16NOV2012 (17) \cell +\pard\intbl\qc\fs16 03:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Rash, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Pqc \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 23APR2013 (175) \cell +\pard\intbl\qc\fs16 23:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1141 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 31MAY2013 (1) \cell +\pard\intbl\qc\fs16 10:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15JUN2013 (16) \cell +\pard\intbl\qc\fs16 09:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1209 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27MAY2013 (1) \cell +\pard\intbl\qc\fs16 03:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15JUN2013 (20) \cell +\pard\intbl\qc\fs16 09:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 15NOV2013 (173) \cell +\pard\intbl\qc\fs16 17:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1288 \cell +\pard\intbl\qc\fs16 77 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04DEC2013 (1) \cell +\pard\intbl\qc\fs16 03:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 18DEC2013 (15) \cell +\pard\intbl\qc\fs16 19:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 28MAY2014 (176) \cell +\pard\intbl\qc\fs16 12:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1319 \cell +\pard\intbl\qc\fs16 65 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17FEB2013 (1) \cell +\pard\intbl\qc\fs16 09:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 04MAR2013 (16) \cell +\pard\intbl\qc\fs16 21:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1321 \cell +\pard\intbl\qc\fs16 75 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 11FEB2014 (1) \cell +\pard\intbl\qc\fs16 04:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 27FEB2014 (17) \cell +\pard\intbl\qc\fs16 00:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1071 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08JUN2013 (1) \cell +\pard\intbl\qc\fs16 12:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Urinary placement catheter could not into the bladder. \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 23JUN2013 (16) \cell +\pard\intbl\qc\fs16 14:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1189 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Bladder mapping performed on 20 nov 2023 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 09OCT2012 (1) \cell +\pard\intbl\qc\fs16 22:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Pqc \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 25OCT2012 (17) \cell +\pard\intbl\qc\fs16 13:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1229 \cell +\pard\intbl\qc\fs16 73 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 20FEB2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Headache, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 07MAR2013 (16) \cell +\pard\intbl\qc\fs16 06:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1364 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 04JUL2013 (1) \cell +\pard\intbl\qc\fs16 08:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 18JUL2013 (15) \cell +\pard\intbl\qc\fs16 18:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 24DEC2013 (174) \cell +\pard\intbl\qc\fs16 14:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1373 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 14DEC2012 (1) \cell +\pard\intbl\qc\fs16 04:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 31DEC2012 (18) \cell +\pard\intbl\qc\fs16 05:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1418 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 05MAY2013 (1) \cell +\pard\intbl\qc\fs16 08:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Pqc was reported. \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 20MAY2013 (16) \cell +\pard\intbl\qc\fs16 14:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Vomiting, Pyrexia) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 07NOV2013 (187) \cell +\pard\intbl\qc\fs16 03:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1447 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Fatigue, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 16DEC2013 (1) \cell +\pard\intbl\qc\fs16 06:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 01JAN2014 (17) \cell +\pard\intbl\qc\fs16 17:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08JUN2014 (175) \cell +\pard\intbl\qc\fs16 09:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1109 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 27JAN2014 (1) \cell +\pard\intbl\qc\fs16 10:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Due to personal schedule \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 11FEB2014 (16) \cell +\pard\intbl\qc\fs16 08:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 19JUL2014 (174) \cell +\pard\intbl\qc\fs16 18:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1174 \cell +\pard\intbl\qc\fs16 73 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 22JAN2013 (1) \cell +\pard\intbl\qc\fs16 18:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 05FEB2013 (15) \cell +\pard\intbl\qc\fs16 01:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 08JUL2013 (168) \cell +\pard\intbl\qc\fs16 21:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1357 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Progression \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01MAY2013 (1) \cell +\pard\intbl\qc\fs16 22:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 16MAY2013 (16) \cell +\pard\intbl\qc\fs16 00:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1101 \cell +\pard\intbl\qc\fs16 82 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17FEB2013 (1) \cell +\pard\intbl\qc\fs16 10:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 04MAR2013 (16) \cell +\pard\intbl\qc\fs16 02:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1328 \cell +\pard\intbl\qc\fs16 86 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Rash, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 01FEB2013 (1) \cell +\pard\intbl\qc\fs16 18:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 15FEB2013 (15) \cell +\pard\intbl\qc\fs16 07:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1371 \cell +\pard\intbl\qc\fs16 69 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 26APR2013 (1) \cell +\pard\intbl\qc\fs16 21:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Tar200 was half blocked by the exit port of the upc \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 09MAY2013 (14) \cell +\pard\intbl\qc\fs16 21:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1427 \cell +\pard\intbl\qc\fs16 74 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 7.5 \cell +\pard\intbl\qc\fs16 7.5 mg \cell +\pard\intbl\qc\fs16 17DEC2012 (1) \cell +\pard\intbl\qc\fs16 23:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 15 \cell +\pard\intbl\qc\fs16 15 mg \cell +\pard\intbl\qc\fs16 01JAN2013 (16) \cell +\pard\intbl\qc\fs16 06:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Placebo \cell +\pard\intbl\qc\fs16 01-701-1015 \cell +\pard\intbl\qc\fs16 63 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02JAN2014 (1) \cell +\pard\intbl\qc\fs16 02:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17JAN2014 (16) \cell +\pard\intbl\qc\fs16 02:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19JUN2014 (169) \cell +\pard\intbl\qc\fs16 00:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1023 \cell +\pard\intbl\qc\fs16 64 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Urine culture not disponible \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05AUG2012 (1) \cell +\pard\intbl\qc\fs16 16:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28AUG2012 (24) \cell +\pard\intbl\qc\fs16 17:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1047 \cell +\pard\intbl\qc\fs16 85 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12FEB2013 (1) \cell +\pard\intbl\qc\fs16 08:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26FEB2013 (15) \cell +\pard\intbl\qc\fs16 07:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1118 \cell +\pard\intbl\qc\fs16 52 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Vomiting, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12MAR2014 (1) \cell +\pard\intbl\qc\fs16 17:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27MAR2014 (16) \cell +\pard\intbl\qc\fs16 21:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28AUG2014 (170) \cell +\pard\intbl\qc\fs16 14:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1130 \cell +\pard\intbl\qc\fs16 84 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Vomiting, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 15FEB2014 (1) \cell +\pard\intbl\qc\fs16 11:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02MAR2014 (16) \cell +\pard\intbl\qc\fs16 10:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03AUG2014 (170) \cell +\pard\intbl\qc\fs16 00:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1153 \cell +\pard\intbl\qc\fs16 79 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23SEP2013 (1) \cell +\pard\intbl\qc\fs16 20:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Diarrhoea, Pyrexia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09OCT2013 (17) \cell +\pard\intbl\qc\fs16 06:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12MAR2014 (171) \cell +\pard\intbl\qc\fs16 08:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1203 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Rash, Pyrexia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02FEB2013 (1) \cell +\pard\intbl\qc\fs16 11:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Sheet could not into the bladder \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24FEB2013 (23) \cell +\pard\intbl\qc\fs16 06:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23JUL2013 (172) \cell +\pard\intbl\qc\fs16 11:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1234 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 30MAR2013 (1) \cell +\pard\intbl\qc\fs16 03:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22APR2013 (24) \cell +\pard\intbl\qc\fs16 00:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11SEP2013 (166) \cell +\pard\intbl\qc\fs16 05:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1345 \cell +\pard\intbl\qc\fs16 63 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08OCT2013 (1) \cell +\pard\intbl\qc\fs16 00:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25OCT2013 (18) \cell +\pard\intbl\qc\fs16 16:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1363 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 30MAY2013 (1) \cell +\pard\intbl\qc\fs16 15:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13JUN2013 (15) \cell +\pard\intbl\qc\fs16 18:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14NOV2013 (169) \cell +\pard\intbl\qc\fs16 08:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1387 \cell +\pard\intbl\qc\fs16 87 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Sheet could not into the bladder \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12MAR2014 (1) \cell +\pard\intbl\qc\fs16 15:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1392 \cell +\pard\intbl\qc\fs16 78 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28OCT2012 (1) \cell +\pard\intbl\qc\fs16 10:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12NOV2012 (16) \cell +\pard\intbl\qc\fs16 22:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16APR2013 (171) \cell +\pard\intbl\qc\fs16 19:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1415 \cell +\pard\intbl\qc\fs16 85 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23SEP2013 (1) \cell +\pard\intbl\qc\fs16 04:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08OCT2013 (16) \cell +\pard\intbl\qc\fs16 03:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Diarrhoea, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11MAR2014 (170) \cell +\pard\intbl\qc\fs16 09:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1440 \cell +\pard\intbl\qc\fs16 70 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08AUG2013 (1) \cell +\pard\intbl\qc\fs16 05:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Nausea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24AUG2013 (17) \cell +\pard\intbl\qc\fs16 19:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Drug was never administered because the subject dropped out prior to first dose \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23JAN2014 (169) \cell +\pard\intbl\qc\fs16 10:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1042 \cell +\pard\intbl\qc\fs16 64 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Adverse event (AE: Rash, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02MAR2013 (1) \cell +\pard\intbl\qc\fs16 18:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 15MAR2013 (14) \cell +\pard\intbl\qc\fs16 14:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10AUG2013 (162) \cell +\pard\intbl\qc\fs16 19:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1096 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Suspicion of disease progression \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25JAN2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10FEB2013 (17) \cell +\pard\intbl\qc\fs16 23:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1100 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13MAR2013 (1) \cell +\pard\intbl\qc\fs16 04:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Vomiting, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 30MAR2013 (18) \cell +\pard\intbl\qc\fs16 06:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 29AUG2013 (170) \cell +\pard\intbl\qc\fs16 20:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1175 \cell +\pard\intbl\qc\fs16 75 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Cystoscopy with lesion. Rtu pending \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20DEC2013 (1) \cell +\pard\intbl\qc\fs16 01:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1210 \cell +\pard\intbl\qc\fs16 72 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16MAR2013 (1) \cell +\pard\intbl\qc\fs16 10:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 31MAR2013 (16) \cell +\pard\intbl\qc\fs16 09:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25AUG2013 (163) \cell +\pard\intbl\qc\fs16 09:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1299 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12SEP2012 (1) \cell +\pard\intbl\qc\fs16 12:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: The device could not push tar-200 out. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 29SEP2012 (18) \cell +\pard\intbl\qc\fs16 04:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02MAR2013 (172) \cell +\pard\intbl\qc\fs16 14:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1010 \cell +\pard\intbl\qc\fs16 80 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 21FEB2014 (1) \cell +\pard\intbl\qc\fs16 02:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Pt had his 24w turb on 22th of december so tar was removed at that time \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09MAR2014 (17) \cell +\pard\intbl\qc\fs16 15:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1127 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02OCT2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17OCT2013 (16) \cell +\pard\intbl\qc\fs16 00:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18MAR2014 (168) \cell +\pard\intbl\qc\fs16 10:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1164 \cell +\pard\intbl\qc\fs16 67 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19SEP2012 (1) \cell +\pard\intbl\qc\fs16 02:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05OCT2012 (17) \cell +\pard\intbl\qc\fs16 21:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18MAR2013 (181) \cell +\pard\intbl\qc\fs16 06:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1233 \cell +\pard\intbl\qc\fs16 87 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 21MAR2013 (1) \cell +\pard\intbl\qc\fs16 04:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05APR2013 (16) \cell +\pard\intbl\qc\fs16 19:00 / UTC \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1260 \cell +\pard\intbl\qc\fs16 71 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 30AUG2012 (1) \cell +\pard\intbl\qc\fs16 11:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was identified \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14SEP2012 (16) \cell +\pard\intbl\qc\fs16 15:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1351 \cell +\pard\intbl\qc\fs16 70 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12OCT2013 (1) \cell +\pard\intbl\qc\fs16 05:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27OCT2013 (16) \cell +\pard\intbl\qc\fs16 08:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Headache, Pyrexia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05APR2014 (176) \cell +\pard\intbl\qc\fs16 08:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1388 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Headache, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Headache, Pyrexia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 07DEC2012 (1) \cell +\pard\intbl\qc\fs16 20:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Insertion failed \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22DEC2012 (16) \cell +\pard\intbl\qc\fs16 05:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Fatigue) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24MAY2013 (169) \cell +\pard\intbl\qc\fs16 06:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1435 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17NOV2012 (1) \cell +\pard\intbl\qc\fs16 15:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02DEC2012 (16) \cell +\pard\intbl\qc\fs16 07:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1445 \cell +\pard\intbl\qc\fs16 75 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11MAY2014 (1) \cell +\pard\intbl\qc\fs16 14:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26MAY2014 (16) \cell +\pard\intbl\qc\fs16 20:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1018 \cell +\pard\intbl\qc\fs16 69 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05JUL2013 (1) \cell +\pard\intbl\qc\fs16 01:00 / UTC \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1059 \cell +\pard\intbl\qc\fs16 66 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Diarrhoea, Anaemia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05AUG2013 (1) \cell +\pard\intbl\qc\fs16 10:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Vomiting, Anaemia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20AUG2013 (16) \cell +\pard\intbl\qc\fs16 10:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1186 \cell +\pard\intbl\qc\fs16 84 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08JAN2014 (1) \cell +\pard\intbl\qc\fs16 23:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24JAN2014 (17) \cell +\pard\intbl\qc\fs16 23:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1282 \cell +\pard\intbl\qc\fs16 70 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26DEC2012 (1) \cell +\pard\intbl\qc\fs16 22:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10JAN2013 (16) \cell +\pard\intbl\qc\fs16 04:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: The device could not push tar-200 out. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12JUN2013 (169) \cell +\pard\intbl\qc\fs16 21:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1349 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Drug was never administered because the subject dropped out prior to first dose \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10MAR2013 (1) \cell +\pard\intbl\qc\fs16 03:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25MAR2013 (16) \cell +\pard\intbl\qc\fs16 22:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26AUG2013 (170) \cell +\pard\intbl\qc\fs16 20:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-706-1041 \cell +\pard\intbl\qc\fs16 64 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Tar200 was half blocked by the exit port of the upc \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 31DEC2013 (1) \cell +\pard\intbl\qc\fs16 15:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Headache, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 15JAN2014 (16) \cell +\pard\intbl\qc\fs16 10:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16JUL2014 (198) \cell +\pard\intbl\qc\fs16 14:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-707-1206 \cell +\pard\intbl\qc\fs16 65 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Personal reasons \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28OCT2013 (1) \cell +\pard\intbl\qc\fs16 22:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13NOV2013 (17) \cell +\pard\intbl\qc\fs16 03:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14APR2014 (169) \cell +\pard\intbl\qc\fs16 02:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1087 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Rash, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22OCT2012 (1) \cell +\pard\intbl\qc\fs16 04:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06NOV2012 (16) \cell +\pard\intbl\qc\fs16 16:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11APR2013 (172) \cell +\pard\intbl\qc\fs16 13:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1158 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08FEB2014 (1) \cell +\pard\intbl\qc\fs16 02:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Urine culture not disponible \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27FEB2014 (20) \cell +\pard\intbl\qc\fs16 14:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1171 \cell +\pard\intbl\qc\fs16 77 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06DEC2012 (1) \cell +\pard\intbl\qc\fs16 23:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Fatigue, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19DEC2012 (14) \cell +\pard\intbl\qc\fs16 14:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 21MAY2013 (167) \cell +\pard\intbl\qc\fs16 22:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1253 \cell +\pard\intbl\qc\fs16 61 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 07MAY2013 (1) \cell +\pard\intbl\qc\fs16 00:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: During week 12, the cystoscopy was performed and suspicion of progression was observed. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22MAY2013 (16) \cell +\pard\intbl\qc\fs16 00:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Tar-200 did not take the pretzel shape inside the bladder. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28OCT2013 (175) \cell +\pard\intbl\qc\fs16 11:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1286 \cell +\pard\intbl\qc\fs16 80 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10SEP2013 (1) \cell +\pard\intbl\qc\fs16 19:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24SEP2013 (15) \cell +\pard\intbl\qc\fs16 19:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24FEB2014 (168) \cell +\pard\intbl\qc\fs16 01:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1296 \cell +\pard\intbl\qc\fs16 57 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Vomiting, Neutropenia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14JUN2013 (1) \cell +\pard\intbl\qc\fs16 18:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Tar-200 did not take the pretzel shape inside the bladder. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28JUN2013 (15) \cell +\pard\intbl\qc\fs16 13:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28NOV2013 (168) \cell +\pard\intbl\qc\fs16 14:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1316 \cell +\pard\intbl\qc\fs16 74 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23AUG2013 (1) \cell +\pard\intbl\qc\fs16 14:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06SEP2013 (15) \cell +\pard\intbl\qc\fs16 16:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16FEB2014 (178) \cell +\pard\intbl\qc\fs16 16:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1342 \cell +\pard\intbl\qc\fs16 59 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 29DEC2012 (1) \cell +\pard\intbl\qc\fs16 06:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13JAN2013 (16) \cell +\pard\intbl\qc\fs16 14:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16JUN2013 (170) \cell +\pard\intbl\qc\fs16 02:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1378 \cell +\pard\intbl\qc\fs16 67 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03SEP2013 (1) \cell +\pard\intbl\qc\fs16 01:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22SEP2013 (20) \cell +\pard\intbl\qc\fs16 00:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1001 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08OCT2013 (1) \cell +\pard\intbl\qc\fs16 14:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23OCT2013 (16) \cell +\pard\intbl\qc\fs16 01:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18MAR2014 (162) \cell +\pard\intbl\qc\fs16 14:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1088 \cell +\pard\intbl\qc\fs16 69 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12APR2014 (1) \cell +\pard\intbl\qc\fs16 20:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27APR2014 (16) \cell +\pard\intbl\qc\fs16 01:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28SEP2014 (170) \cell +\pard\intbl\qc\fs16 04:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1259 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Progression \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26JAN2013 (1) \cell +\pard\intbl\qc\fs16 17:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was reported. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11FEB2013 (17) \cell +\pard\intbl\qc\fs16 13:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1301 \cell +\pard\intbl\qc\fs16 62 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19JUL2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03AUG2013 (16) \cell +\pard\intbl\qc\fs16 07:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05JAN2014 (171) \cell +\pard\intbl\qc\fs16 02:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1306 \cell +\pard\intbl\qc\fs16 60 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03FEB2014 (1) \cell +\pard\intbl\qc\fs16 03:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20FEB2014 (18) \cell +\pard\intbl\qc\fs16 16:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1312 \cell +\pard\intbl\qc\fs16 68 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20APR2014 (1) \cell +\pard\intbl\qc\fs16 23:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Vomiting, Neutropenia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11MAY2014 (22) \cell +\pard\intbl\qc\fs16 04:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06OCT2014 (170) \cell +\pard\intbl\qc\fs16 04:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1339 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23DEC2012 (1) \cell +\pard\intbl\qc\fs16 11:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06JAN2013 (15) \cell +\pard\intbl\qc\fs16 13:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Vomiting, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09JUN2013 (169) \cell +\pard\intbl\qc\fs16 18:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1027 \cell +\pard\intbl\qc\fs16 83 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28FEB2014 (1) \cell +\pard\intbl\qc\fs16 17:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Diarrhoea, Pyrexia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 15MAR2014 (16) \cell +\pard\intbl\qc\fs16 07:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion rate increased / Other: Bladder mapping performed on 20 nov 2023 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20AUG2014 (174) \cell +\pard\intbl\qc\fs16 16:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1060 \cell +\pard\intbl\qc\fs16 82 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 01JAN2013 (1) \cell +\pard\intbl\qc\fs16 04:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Diarrhoea, Neutropenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16JAN2013 (16) \cell +\pard\intbl\qc\fs16 01:00 / 07:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Nausea, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22JUN2013 (173) \cell +\pard\intbl\qc\fs16 00:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1077 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17NOV2013 (1) \cell +\pard\intbl\qc\fs16 16:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02DEC2013 (16) \cell +\pard\intbl\qc\fs16 19:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 04MAY2014 (169) \cell +\pard\intbl\qc\fs16 15:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1078 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17SEP2013 (1) \cell +\pard\intbl\qc\fs16 01:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Adverse event (AE: Diarrhoea, Oedema peripheral) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 07OCT2013 (21) \cell +\pard\intbl\qc\fs16 23:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Other: Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09MAR2014 (174) \cell +\pard\intbl\qc\fs16 21:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1083 \cell +\pard\intbl\qc\fs16 89 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22JUL2013 (1) \cell +\pard\intbl\qc\fs16 20:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1183 \cell +\pard\intbl\qc\fs16 80 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16NOV2013 (1) \cell +\pard\intbl\qc\fs16 22:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 01DEC2013 (16) \cell +\pard\intbl\qc\fs16 21:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 04MAY2014 (170) \cell +\pard\intbl\qc\fs16 12:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1264 \cell +\pard\intbl\qc\fs16 78 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13JUN2013 (1) \cell +\pard\intbl\qc\fs16 15:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28JUN2013 (16) \cell +\pard\intbl\qc\fs16 02:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1271 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Adverse event (AE: Headache, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27SEP2012 (1) \cell +\pard\intbl\qc\fs16 15:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Low neutrophil count \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13OCT2012 (17) \cell +\pard\intbl\qc\fs16 18:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1314 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Adverse event (AE: Diarrhoea, Thrombocytopenia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24APR2013 (1) \cell +\pard\intbl\qc\fs16 01:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10MAY2013 (17) \cell +\pard\intbl\qc\fs16 23:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1315 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27FEB2013 (1) \cell +\pard\intbl\qc\fs16 06:00 / 16:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14MAR2013 (16) \cell +\pard\intbl\qc\fs16 21:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1368 \cell +\pard\intbl\qc\fs16 88 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 23OCT2013 (1) \cell +\pard\intbl\qc\fs16 21:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 07NOV2013 (16) \cell +\pard\intbl\qc\fs16 09:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10APR2014 (170) \cell +\pard\intbl\qc\fs16 02:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-711-1036 \cell +\pard\intbl\qc\fs16 70 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 29JUL2012 (1) \cell +\pard\intbl\qc\fs16 20:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Diarrhoea, Pyrexia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13AUG2012 (16) \cell +\pard\intbl\qc\fs16 15:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14JAN2013 (170) \cell +\pard\intbl\qc\fs16 23:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1179 \cell +\pard\intbl\qc\fs16 64 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Tar200 was blocked in the middle of the upc hole \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09AUG2013 (1) \cell +\pard\intbl\qc\fs16 03:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Cystoscopy with lesion. Rtu pending \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25AUG2013 (17) \cell +\pard\intbl\qc\fs16 23:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25JAN2014 (170) \cell +\pard\intbl\qc\fs16 11:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1256 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19SEP2012 (1) \cell +\pard\intbl\qc\fs16 14:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 04OCT2012 (16) \cell +\pard\intbl\qc\fs16 11:00 / 08:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 10MAR2013 (173) \cell +\pard\intbl\qc\fs16 01:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-713-1269 \cell +\pard\intbl\qc\fs16 73 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Diarrhoea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27JAN2014 (1) \cell +\pard\intbl\qc\fs16 18:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Other \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11FEB2014 (16) \cell +\pard\intbl\qc\fs16 16:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 14JUL2014 (169) \cell +\pard\intbl\qc\fs16 12:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1035 \cell +\pard\intbl\qc\fs16 88 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17APR2014 (1) \cell +\pard\intbl\qc\fs16 07:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02MAY2014 (16) \cell +\pard\intbl\qc\fs16 20:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03OCT2014 (170) \cell +\pard\intbl\qc\fs16 12:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-714-1375 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 26FEB2013 (1) \cell +\pard\intbl\qc\fs16 02:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20MAR2013 (23) \cell +\pard\intbl\qc\fs16 13:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24AUG2013 (180) \cell +\pard\intbl\qc\fs16 03:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1155 \cell +\pard\intbl\qc\fs16 59 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13DEC2013 (1) \cell +\pard\intbl\qc\fs16 13:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28DEC2013 (16) \cell +\pard\intbl\qc\fs16 16:00 / 22:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1207 \cell +\pard\intbl\qc\fs16 78 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18NOV2012 (1) \cell +\pard\intbl\qc\fs16 04:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Other medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03DEC2012 (16) \cell +\pard\intbl\qc\fs16 13:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06MAY2013 (170) \cell +\pard\intbl\qc\fs16 02:00 / 05:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-715-1397 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Non-hematologic toxicity \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03APR2013 (1) \cell +\pard\intbl\qc\fs16 17:00 / 09:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Other: Pqc was reported. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19APR2013 (17) \cell +\pard\intbl\qc\fs16 14:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19SEP2013 (170) \cell +\pard\intbl\qc\fs16 17:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1024 \cell +\pard\intbl\qc\fs16 87 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Fatigue, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 Infusion aborted / Medical reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09JUL2012 (1) \cell +\pard\intbl\qc\fs16 15:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 Infusion interrupted / Other: Patient's vacation \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 24JUL2012 (16) \cell +\pard\intbl\qc\fs16 14:00 / 14:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Pending lab results \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 31DEC2012 (176) \cell +\pard\intbl\qc\fs16 16:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1026 \cell +\pard\intbl\qc\fs16 73 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02APR2014 (1) \cell +\pard\intbl\qc\fs16 19:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19APR2014 (18) \cell +\pard\intbl\qc\fs16 22:00 / 21:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28SEP2014 (180) \cell +\pard\intbl\qc\fs16 06:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1044 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Pqc \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27APR2013 (1) \cell +\pard\intbl\qc\fs16 17:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Rash) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11MAY2013 (15) \cell +\pard\intbl\qc\fs16 13:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Fatigue, Anaemia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Anemia \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17OCT2013 (174) \cell +\pard\intbl\qc\fs16 20:00 / 03:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1108 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Full dose administered with interruption / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Thrombocytopenia \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 12FEB2013 (1) \cell +\pard\intbl\qc\fs16 22:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Dose reduced / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Pqc \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 27FEB2013 (16) \cell +\pard\intbl\qc\fs16 10:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03AUG2013 (173) \cell +\pard\intbl\qc\fs16 20:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1160 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 05APR2013 (1) \cell +\pard\intbl\qc\fs16 23:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Urine culture not disponible \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 20APR2013 (16) \cell +\pard\intbl\qc\fs16 05:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Study drug permanently discontinued / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Physician decision \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: The dose delayed due to turb performed 10-nov-2023 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28SEP2013 (177) \cell +\pard\intbl\qc\fs16 06:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1177 \cell +\pard\intbl\qc\fs16 72 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior infusion / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Adverse event (AE: Headache) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 02SEP2014 (1) \cell +\pard\intbl\qc\fs16 08:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Fatigue, Oedema peripheral) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17SEP2014 (16) \cell +\pard\intbl\qc\fs16 07:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Diarrhoea, Anaemia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 18FEB2015 (170) \cell +\pard\intbl\qc\fs16 13:00 / 12:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1308 \cell +\pard\intbl\qc\fs16 76 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Personal reasons \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28AUG2013 (1) \cell +\pard\intbl\qc\fs16 20:00 / 15:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Infusion delayed within the cycle / Adverse event (AE: Diarrhoea, Pyrexia) \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Adverse event \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 13SEP2013 (17) \cell +\pard\intbl\qc\fs16 18:00 / 18:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-716-1441 \cell +\pard\intbl\qc\fs16 85 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 22JAN2014 (1) \cell +\pard\intbl\qc\fs16 23:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 07FEB2014 (17) \cell +\pard\intbl\qc\fs16 08:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Other: Personal reasons \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 09JUL2014 (169) \cell +\pard\intbl\qc\fs16 07:00 / 13:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1201 \cell +\pard\intbl\qc\fs16 85 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 6 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Subject request \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19DEC2013 (1) \cell +\pard\intbl\qc\fs16 02:00 / 00:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Administrative reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Recovery from toxicity \cell +\pard\intbl\qc\fs16 Infusion rate increased / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 04JAN2014 (17) \cell +\pard\intbl\qc\fs16 14:00 / 04:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-717-1344 \cell +\pard\intbl\qc\fs16 64 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Full dose administered without interruption or rate change / Adverse event (AE: Nausea) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 11JAN2014 (1) \cell +\pard\intbl\qc\fs16 12:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced compared to prior injection / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 25JAN2014 (15) \cell +\pard\intbl\qc\fs16 21:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1139 \cell +\pard\intbl\qc\fs16 77 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19MAY2013 (1) \cell +\pard\intbl\qc\fs16 14:00 / 10:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Infusion rate decreased compared to prior infusion / Administrative reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03JUN2013 (16) \cell +\pard\intbl\qc\fs16 02:00 / 06:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Infusion skipped (and not made up) / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 04NOV2013 (170) \cell +\pard\intbl\qc\fs16 21:00 / 17:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1150 \cell +\pard\intbl\qc\fs16 73 / Female / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 7 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 19JAN2013 (1) \cell +\pard\intbl\qc\fs16 14:00 / 02:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion continued at same rate / Other: Multiple tumors identified by cystoscopy on week 12. \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 03FEB2013 (16) \cell +\pard\intbl\qc\fs16 16:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion rate increased / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 08JUL2013 (171) \cell +\pard\intbl\qc\fs16 16:00 / 23:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1172 \cell +\pard\intbl\qc\fs16 74 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion interrupted / Subject request \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 21SEP2013 (1) \cell +\pard\intbl\qc\fs16 10:00 / 11:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Dose reduced / Physician decision \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 N \cell +\pard\intbl\qc\fs16 Infusion aborted / Physician decision \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 06OCT2013 (16) \cell +\pard\intbl\qc\fs16 20:00 / 20:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-718-1355 \cell +\pard\intbl\qc\fs16 79 / Male / White \cell +\pard\intbl\qc\fs16 Screening \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Same dose as prior infusion / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Subject request \cell +\pard\intbl\qc\fs16 Infusion aborted / Adverse event (AE: Fatigue, Anaemia) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 28FEB2013 (1) \cell +\pard\intbl\qc\fs16 11:00 / 19:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 02 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Reduced [target/treatment] / Other: Personal reasons \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Missed visit \cell +\pard\intbl\qc\fs16 Infusion aborted / Administrative reason \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 17MAR2013 (18) \cell +\pard\intbl\qc\fs16 23:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx887 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1435 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2152 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2870 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3629 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4389 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5781 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6541 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7891 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9283 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10212 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11182 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12153 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Cycle 09 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 Dose re-escalated / Medical reason \cell +\pard\intbl\qc\fs16 QD \cell +\pard\intbl\qc\fs16 Y / Infection \cell +\pard\intbl\qc\fs16 Infusion interrupted / Adverse event (AE: Vomiting) \cell +\pard\intbl\qc\fs16 0 \cell +\pard\intbl\qc\fs16 0 mg \cell +\pard\intbl\qc\fs16 16AUG2013 (170) \cell +\pard\intbl\qc\fs16 06:00 / 01:00 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx887 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1435 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2152 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2870 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3629 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx4389 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx5781 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6541 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7891 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9283 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10212 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11182 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12153 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx887 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1435 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2152 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2870 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3629 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx4389 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx5781 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6541 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7891 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9283 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10212 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11182 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12153 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} +\par {\footer\pard\sb240\qr\fs16{\insrsid2691151 Listing Page }{\field{\*\fldinst {\insrsid2691151 PAGE }}{\fldrslt {\insrsid26911511}}}{\insrsid2691151 of }{\field{\*\fldinst {\insrsid2691151 NUMPAGES }} {\fldrslt {\insrsid112265262}}}{\insrsid2691151 \par }} +} \ No newline at end of file diff --git a/tests/testthat/_snaps/lsimh01/lsimh01.rtf b/tests/testthat/_snaps/lsimh01/lsimh01.rtf old mode 100755 new mode 100644 index 41358f35..2605ef27 --- a/tests/testthat/_snaps/lsimh01/lsimh01.rtf +++ b/tests/testthat/_snaps/lsimh01/lsimh01.rtf @@ -5,8 +5,8 @@ \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6373 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3922 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7398 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9225 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10250 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11275 @@ -27,8 +27,8 @@ \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx936 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx1516 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6373 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3922 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7398 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9225 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10250 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11275 @@ -37,7 +37,7 @@ \pard\intbl\qc\fs16 \keepn\trhdr Subject ID \cell \pard\intbl\qc\fs16 \keepn\trhdr Age (years) / Sex / Race \cell \pard\intbl\qc\fs16 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs16 \keepn\trhdr [Preferred Term / Reported Term] \cell +\pard\intbl\qc\fs16 \keepn\trhdr Preferred Term / Reported Term \cell \pard\intbl\qc\fs16 \keepn\trhdr Start Date (Study Day)\super a\nosupersub \cell \pard\intbl\qc\fs16 \keepn\trhdr End Date (Study Day)\super a\nosupersub \cell \pard\intbl\qc\fs16 \keepn\trhdr Ongoing? \cell @@ -49,18 +49,18 @@ \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline High Dose \cell -\pard\intbl\qc\fs16 01-701-1028 \cell -\pard\intbl\qc\fs16 71 / M / Asian \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 APPENDICECTOMY / VERBATIM_1775 \cell -\pard\intbl\qc\fs16 1968 \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 Xanomeline Low Dose \cell +\pard\intbl\qc\fs16 01-701-1033 \cell +\pard\intbl\qc\fs16 74 / Male / Multiple \cell +\pard\intbl\qc\fs16 Nervous system disorders \cell +\pard\intbl\qc\fs16 Syncope / verbatim_0581 \cell +\pard\intbl\qc\fs16 1982 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 2 \cell @@ -71,8 +71,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -80,12 +80,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 LIPECTOMY / VERBATIM_1006 \cell -\pard\intbl\qc\fs16 1981 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Umbilical hernia repair / verbatim_0116 \cell +\pard\intbl\qc\fs16 1993 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -93,8 +93,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -102,12 +102,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 / ALZHEIMER'S DISEASE \cell -\pard\intbl\qc\fs16 16DEC2009 (-1311) \cell -\pard\intbl\qc\fs16 24NOV2010 (-968) \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 02AUG2009 (-1689) \cell +\pard\intbl\qc\fs16 12AUG2010 (-1314) \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -115,8 +115,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -124,12 +124,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 EYE DISORDERS \cell -\pard\intbl\qc\fs16 PRESBYOPIA / VERBATIM_0507 \cell +\pard\intbl\qc\fs16 General disorders and administration site conditions \cell +\pard\intbl\qc\fs16 Oedema peripheral / verbatim_1653 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -137,17 +137,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 ARTHRITIS / VERBATIM_1686 \cell +\pard\intbl\qc\fs16 01-701-1097 \cell +\pard\intbl\qc\fs16 68 / Male / Other \cell +\pard\intbl\qc\fs16 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs16 Monarthritis / verbatim_0662 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell @@ -159,40 +159,18 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 NEOPLASMS BENIGN, MALIGNANT AND UNSPECIFIED (INCL CYSTS AND POLYPS) \cell -\pard\intbl\qc\fs16 LIPOMA / VERBATIM_0428 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 5 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1034 \cell -\pard\intbl\qc\fs16 77 / F / White \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 TONSILLECTOMY / VERBATIM_1716 \cell -\pard\intbl\qc\fs16 1946 \cell +\pard\intbl\qc\fs16 01-701-1111 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs16 Upper limb fracture / verbatim_1378 \cell +\pard\intbl\qc\fs16 1986 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 4 \cell @@ -203,8 +181,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -212,12 +190,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 APPENDICECTOMY / VERBATIM_1775 \cell -\pard\intbl\qc\fs16 1949 \cell +\pard\intbl\qc\fs16 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs16 Cough / verbatim_0910 \cell +\pard\intbl\qc\fs16 2002 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -225,8 +203,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -234,12 +212,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 HYSTERECTOMY / VERBATIM_0936 \cell -\pard\intbl\qc\fs16 1960 \cell +\pard\intbl\qc\fs16 Renal and urinary disorders \cell +\pard\intbl\qc\fs16 Incontinence / verbatim_1545 \cell +\pard\intbl\qc\fs16 2006 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -247,8 +225,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -256,12 +234,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 ANAL FISTULA / VERBATIM_1133 \cell -\pard\intbl\qc\fs16 1962 \cell +\pard\intbl\qc\fs16 Neoplasms benign, malignant and unspecified (incl cysts and polyps) \cell +\pard\intbl\qc\fs16 Basal cell carcinoma / verbatim_0951 \cell +\pard\intbl\qc\fs16 2007 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -269,8 +247,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -278,12 +256,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INJURY, POISONING AND PROCEDURAL COMPLICATIONS \cell -\pard\intbl\qc\fs16 FOOT FRACTURE / VERBATIM_1132 \cell -\pard\intbl\qc\fs16 2004 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 04APR2009 (-1252) \cell +\pard\intbl\qc\fs16 14JAN2010 (-967) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -291,8 +269,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -300,11 +278,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 FACE LIFT / VERBATIM_1162 \cell -\pard\intbl\qc\fs16 21AUG2011 (-1045) \cell -\pard\intbl\qc\fs16 29MAR2012 (-824) \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Ear and labyrinth disorders \cell +\pard\intbl\qc\fs16 Deafness / verbatim_0546 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 1 \cell \row } @@ -313,8 +291,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -322,12 +300,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Ear and labyrinth disorders \cell +\pard\intbl\qc\fs16 Tinnitus / verbatim_1065 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 / ALZHEIMER'S DISEASE \cell -\pard\intbl\qc\fs16 29SEP2011 (-1006) \cell -\pard\intbl\qc\fs16 03MAY2012 (-789) \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -335,8 +313,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -344,12 +322,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INJURY, POISONING AND PROCEDURAL COMPLICATIONS \cell -\pard\intbl\qc\fs16 LOWER LIMB FRACTURE / VERBATIM_0122 \cell -\pard\intbl\qc\fs16 2012 \cell +\pard\intbl\qc\fs16 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs16 Osteoporosis / verbatim_1201 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -357,21 +335,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1115 \cell +\pard\intbl\qc\fs16 84 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Gastrointestinal disorders \cell +\pard\intbl\qc\fs16 Constipation / verbatim_0443 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 MUSCLE SPASMS / VERBATIM_0973 \cell -\pard\intbl\qc\fs16 21DEC2013 (-192) \cell -\pard\intbl\qc\fs16 19JAN2014 (-163) \cell -\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -379,8 +357,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -388,12 +366,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INVESTIGATIONS \cell -\pard\intbl\qc\fs16 BLOOD PRESSURE INCREASED / VERBATIM_1680 \cell -\pard\intbl\qc\fs16 11JUN2014 (-20) \cell -\pard\intbl\qc\fs16 11APR2015 (285) \cell -\pard\intbl\qc\fs16 Yes \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs16 Polyarthritis / verbatim_1546 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4 \cell \row } @@ -401,8 +379,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -410,12 +388,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 ENDOCRINE DISORDERS \cell -\pard\intbl\qc\fs16 HYPOTHYROIDISM / VERBATIM_0692 \cell +\pard\intbl\qc\fs16 Renal and urinary disorders \cell +\pard\intbl\qc\fs16 Micturition urgency / verbatim_1179 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -423,8 +401,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -432,12 +410,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 EYE DISORDERS \cell -\pard\intbl\qc\fs16 HYPERMETROPIA / VERBATIM_1683 \cell +\pard\intbl\qc\fs16 Renal and urinary disorders \cell +\pard\intbl\qc\fs16 Nocturia / verbatim_0014 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -445,8 +423,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -454,12 +432,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 ABDOMINAL PAIN / VERBATIM_1385 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Reproductive system and breast disorders \cell +\pard\intbl\qc\fs16 Prostatitis / verbatim_1350 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 4 \cell \row } @@ -467,18 +445,18 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 CONSTIPATION / VERBATIM_0443 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1181 \cell +\pard\intbl\qc\fs16 79 / Female / Not reported \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Tonsillectomy / verbatim_1716 \cell +\pard\intbl\qc\fs16 1940 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 4 \cell @@ -489,8 +467,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -498,12 +476,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 ARTHRITIS / VERBATIM_0753 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs16 Cough / verbatim_0303 \cell +\pard\intbl\qc\fs16 08JUN2012 (-545) \cell +\pard\intbl\qc\fs16 03NOV2012 (-397) \cell +\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell \row } @@ -511,8 +489,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -520,12 +498,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 ARTHRITIS / VERBATIM_0763 \cell +\pard\intbl\qc\fs16 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs16 Shoulder pain / verbatim_0671 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -533,21 +511,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1133 \cell -\pard\intbl\qc\fs16 81 / F / Other \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 TONSILLECTOMY / VERBATIM_1716 \cell -\pard\intbl\qc\fs16 1939 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 Nervous system disorders \cell +\pard\intbl\qc\fs16 Headache / verbatim_0929 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -555,8 +533,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -564,12 +542,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INVESTIGATIONS \cell -\pard\intbl\qc\fs16 WEIGHT DECREASED / VERBATIM_0293 \cell -\pard\intbl\qc\fs16 1966 \cell +\pard\intbl\qc\fs16 Social circumstances \cell +\pard\intbl\qc\fs16 Denture wearer / verbatim_0686 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -577,21 +555,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1188 \cell +\pard\intbl\qc\fs16 71 / Male / White \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Wisdom teeth removal / verbatim_1729 \cell +\pard\intbl\qc\fs16 1964 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GENERAL DISORDERS AND ADMINISTRATION SITE CONDITIONS \cell -\pard\intbl\qc\fs16 CHEST PAIN / VERBATIM_0517 \cell -\pard\intbl\qc\fs16 1986 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -599,8 +577,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -608,9 +586,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 VASCULAR DISORDERS \cell -\pard\intbl\qc\fs16 HYPERTENSION / VERBATIM_0342 \cell -\pard\intbl\qc\fs16 1986 \cell +\pard\intbl\qc\fs16 Reproductive system and breast disorders \cell +\pard\intbl\qc\fs16 Benign prostatic hyperplasia / verbatim_0138 \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 1 \cell @@ -621,8 +599,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -630,12 +608,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 DIVERTICULUM / VERBATIM_1023 \cell -\pard\intbl\qc\fs16 2000 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs16 Pharyngolaryngeal pain / verbatim_1230 \cell +\pard\intbl\qc\fs16 08JUN2011 (-618) \cell +\pard\intbl\qc\fs16 27MAR2012 (-325) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -643,21 +621,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1192 \cell +\pard\intbl\qc\fs16 80 / Female / Not reported \cell +\pard\intbl\qc\fs16 Pregnancy, puerperium and perinatal conditions \cell +\pard\intbl\qc\fs16 Abortion / verbatim_0435 \cell +\pard\intbl\qc\fs16 1946 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 HAEMORRHOIDS / VERBATIM_0267 \cell -\pard\intbl\qc\fs16 2003 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -665,8 +643,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -674,12 +652,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 KNEE ARTHROPLASTY / VERBATIM_0009 \cell -\pard\intbl\qc\fs16 DEC2009 \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Hip arthroplasty / verbatim_1436 \cell +\pard\intbl\qc\fs16 2000 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell \row } @@ -687,8 +665,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -696,12 +674,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 / ALZHEIMER'S DISEASE \cell -\pard\intbl\qc\fs16 11MAR2010 (-962) \cell -\pard\intbl\qc\fs16 01DEC2010 (-697) \cell +\pard\intbl\qc\fs16 General disorders and administration site conditions \cell +\pard\intbl\qc\fs16 Cyst / verbatim_0576 \cell +\pard\intbl\qc\fs16 22APR2010 (-822) \cell +\pard\intbl\qc\fs16 03JUL2010 (-750) \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -709,8 +687,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -718,12 +696,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 EYE DISORDERS \cell -\pard\intbl\qc\fs16 HYPERMETROPIA / VERBATIM_1683 \cell +\pard\intbl\qc\fs16 Ear and labyrinth disorders \cell +\pard\intbl\qc\fs16 Deafness bilateral / verbatim_1677 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -731,8 +709,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -740,8 +718,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 POLYARTHRITIS / VERBATIM_1121 \cell +\pard\intbl\qc\fs16 Eye disorders \cell +\pard\intbl\qc\fs16 Presbyopia / verbatim_0507 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell @@ -753,21 +731,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SOCIAL CIRCUMSTANCES \cell -\pard\intbl\qc\fs16 DENTURE WEARER / VERBATIM_1796 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1211 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell +\pard\intbl\qc\fs16 Metabolism and nutrition disorders \cell +\pard\intbl\qc\fs16 Diabetes mellitus non-insulin-dependent / verbatim_1573 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -775,18 +753,18 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1146 \cell -\pard\intbl\qc\fs16 75 / F / Unknown \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 TONSILLECTOMY / VERBATIM_1716 \cell -\pard\intbl\qc\fs16 1942 \cell +\pard\intbl\qc\fs16 01-701-1294 \cell +\pard\intbl\qc\fs16 67 / Male / Other \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Tonsillectomy / verbatim_1716 \cell +\pard\intbl\qc\fs16 1946 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 1 \cell @@ -797,8 +775,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -806,12 +784,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RENAL AND URINARY DISORDERS \cell -\pard\intbl\qc\fs16 BLADDER PROLAPSE / VERBATIM_0815 \cell -\pard\intbl\qc\fs16 2006 \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Haemorrhoid operation / verbatim_1187 \cell +\pard\intbl\qc\fs16 1966 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 4 \cell \row } @@ -819,8 +797,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -828,12 +806,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Renal and urinary disorders \cell +\pard\intbl\qc\fs16 Nephrolithiasis / verbatim_0739 \cell +\pard\intbl\qc\fs16 1976 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 / ALZHEIMER'S DISEASE \cell -\pard\intbl\qc\fs16 17NOV2009 (-1280) \cell -\pard\intbl\qc\fs16 23MAR2010 (-1154) \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 2 \cell \row } @@ -841,21 +819,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 OESOPHAGEAL SPASM / VERBATIM_1117 \cell -\pard\intbl\qc\fs16 2011 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-701-1317 \cell +\pard\intbl\qc\fs16 68 / Male / Unknown \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 16SEP2013 (-248) \cell +\pard\intbl\qc\fs16 23APR2014 (-29) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 4 \cell \row } @@ -863,21 +841,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1324 \cell +\pard\intbl\qc\fs16 79 / Male / Asian \cell +\pard\intbl\qc\fs16 Gastrointestinal disorders \cell +\pard\intbl\qc\fs16 Inguinal hernia / verbatim_0206 \cell +\pard\intbl\qc\fs16 2001 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RENAL AND URINARY DISORDERS \cell -\pard\intbl\qc\fs16 BLADDER PROLAPSE / VERBATIM_0815 \cell -\pard\intbl\qc\fs16 2012 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -885,8 +863,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -894,12 +872,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GENERAL DISORDERS AND ADMINISTRATION SITE CONDITIONS \cell -\pard\intbl\qc\fs16 CHEST PAIN / VERBATIM_0517 \cell -\pard\intbl\qc\fs16 27MAR2012 (-419) \cell -\pard\intbl\qc\fs16 04AUG2012 (-289) \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Hernia repair / verbatim_0722 \cell +\pard\intbl\qc\fs16 2001 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -907,8 +885,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -916,12 +894,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 ABDOMINAL DISCOMFORT / VERBATIM_0821 \cell -\pard\intbl\qc\fs16 06JUL2012 (-318) \cell -\pard\intbl\qc\fs16 05APR2013 (-45) \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 11OCT2009 (-1087) \cell +\pard\intbl\qc\fs16 12DEC2009 (-1025) \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -929,20 +907,20 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1341 \cell +\pard\intbl\qc\fs16 51 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs16 Rheumatic fever / verbatim_0433 \cell +\pard\intbl\qc\fs16 1966 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 ENDODONTIC PROCEDURE / VERBATIM_1066 \cell -\pard\intbl\qc\fs16 12SEP2012 (-250) \cell -\pard\intbl\qc\fs16 12APR2013 (-38) \cell -\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 2 \cell \row } @@ -951,8 +929,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -960,11 +938,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INFECTIONS AND INFESTATIONS \cell -\pard\intbl\qc\fs16 CYSTITIS / VERBATIM_0361 \cell -\pard\intbl\qc\fs16 27OCT2012 (-205) \cell -\pard\intbl\qc\fs16 20FEB2013 (-89) \cell -\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs16 Arthritis / verbatim_0676 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 5 \cell \row } @@ -973,21 +951,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-701-1360 \cell +\pard\intbl\qc\fs16 67 / Male / Multiple \cell +\pard\intbl\qc\fs16 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs16 Hand fracture / verbatim_0898 \cell +\pard\intbl\qc\fs16 1986 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 EAR AND LABYRINTH DISORDERS \cell -\pard\intbl\qc\fs16 DEAFNESS / VERBATIM_0391 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -995,17 +973,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 CONSTIPATION / VERBATIM_0443 \cell +\pard\intbl\qc\fs16 01-702-1082 \cell +\pard\intbl\qc\fs16 84 / Female / Asian \cell +\pard\intbl\qc\fs16 Vascular disorders \cell +\pard\intbl\qc\fs16 Aortic stenosis / verbatim_1100 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell @@ -1017,21 +995,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 DIARRHOEA / VERBATIM_1126 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 01-703-1119 \cell +\pard\intbl\qc\fs16 81 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 01FEB2005 (-2941) \cell +\pard\intbl\qc\fs16 24NOV2005 (-2645) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1039,8 +1017,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1048,9 +1026,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INFECTIONS AND INFESTATIONS \cell -\pard\intbl\qc\fs16 SINUSITIS / VERBATIM_1769 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Investigations \cell +\pard\intbl\qc\fs16 Catheterisation cardiac / verbatim_1345 \cell +\pard\intbl\qc\fs16 2006 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 4 \cell @@ -1061,8 +1039,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1070,12 +1048,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INVESTIGATIONS \cell -\pard\intbl\qc\fs16 CARDIAC MURMUR / VERBATIM_1223 \cell +\pard\intbl\qc\fs16 Cardiac disorders \cell +\pard\intbl\qc\fs16 Coronary artery disease / verbatim_0409 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1083,21 +1061,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 ARTHRALGIA / VERBATIM_1441 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 01-703-1182 \cell +\pard\intbl\qc\fs16 84 / Male / Other \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 27SEP2011 (-751) \cell +\pard\intbl\qc\fs16 01DEC2011 (-686) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -1105,8 +1083,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1114,12 +1092,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 POLYARTHRITIS / VERBATIM_0325 \cell +\pard\intbl\qc\fs16 Metabolism and nutrition disorders \cell +\pard\intbl\qc\fs16 Hypercholesterolaemia / verbatim_0164 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1127,8 +1105,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1136,12 +1114,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PSYCHIATRIC DISORDERS \cell -\pard\intbl\qc\fs16 DEPRESSION / VERBATIM_1376 \cell +\pard\intbl\qc\fs16 Vascular disorders \cell +\pard\intbl\qc\fs16 Hypertension / verbatim_0342 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -1149,21 +1127,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1148 \cell -\pard\intbl\qc\fs16 57 / M / Not reported \cell -\pard\intbl\qc\fs16 INJURY, POISONING AND PROCEDURAL COMPLICATIONS \cell -\pard\intbl\qc\fs16 ANKLE FRACTURE / VERBATIM_0146 \cell -\pard\intbl\qc\fs16 1985 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 01-703-1197 \cell +\pard\intbl\qc\fs16 76 / Female / Other \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 11JAN2012 (-522) \cell +\pard\intbl\qc\fs16 24OCT2012 (-235) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -1171,8 +1149,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1180,12 +1158,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 ANAL FISTULA / VERBATIM_0598 \cell -\pard\intbl\qc\fs16 1989 \cell +\pard\intbl\qc\fs16 General disorders and administration site conditions \cell +\pard\intbl\qc\fs16 Oedema peripheral / verbatim_0112 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -1193,21 +1171,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 BREAST LUMP REMOVAL / VERBATIM_0305 \cell -\pard\intbl\qc\fs16 1991 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-703-1279 \cell +\pard\intbl\qc\fs16 72 / Female / Unknown \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 29JUL2010 (-1019) \cell +\pard\intbl\qc\fs16 07JUL2011 (-676) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 4 \cell \row } @@ -1215,21 +1193,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INJURY, POISONING AND PROCEDURAL COMPLICATIONS \cell -\pard\intbl\qc\fs16 THERMAL BURN / VERBATIM_0036 \cell -\pard\intbl\qc\fs16 1996 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 01-703-1379 \cell +\pard\intbl\qc\fs16 81 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 21SEP2009 (-1462) \cell +\pard\intbl\qc\fs16 29MAY2010 (-1212) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -1237,8 +1215,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1246,9 +1224,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 SKIN GRAFT / VERBATIM_1550 \cell -\pard\intbl\qc\fs16 1996 \cell +\pard\intbl\qc\fs16 Metabolism and nutrition disorders \cell +\pard\intbl\qc\fs16 Gout / verbatim_0980 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 2 \cell @@ -1259,8 +1237,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1268,12 +1246,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 ANAL FISTULA / VERBATIM_0598 \cell -\pard\intbl\qc\fs16 2007 \cell +\pard\intbl\qc\fs16 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs16 Osteoarthritis / verbatim_1734 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1281,21 +1259,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-703-1403 \cell +\pard\intbl\qc\fs16 67 / Male / Multiple \cell +\pard\intbl\qc\fs16 Ear and labyrinth disorders \cell +\pard\intbl\qc\fs16 Hypoacusis / verbatim_0786 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 SINUS OPERATION / VERBATIM_0807 \cell -\pard\intbl\qc\fs16 2010 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell \row } @@ -1303,8 +1281,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1312,11 +1290,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs16 Skin laceration / verbatim_1610 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 / ALZHEIMER'S DISEASE \cell -\pard\intbl\qc\fs16 12DEC2010 (-985) \cell -\pard\intbl\qc\fs16 13OCT2011 (-680) \cell -\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 1 \cell \row } @@ -1325,21 +1303,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1025 \cell +\pard\intbl\qc\fs16 81 / Female / Asian \cell +\pard\intbl\qc\fs16 Cardiac disorders \cell +\pard\intbl\qc\fs16 Atrial tachycardia / verbatim_1472 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SKIN AND SUBCUTANEOUS TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 ACTINIC KERATOSIS / VERBATIM_1160 \cell -\pard\intbl\qc\fs16 2011 \cell -\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -1347,17 +1325,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 CARDIAC DISORDERS \cell -\pard\intbl\qc\fs16 PALPITATIONS / VERBATIM_0266 \cell +\pard\intbl\qc\fs16 01-704-1120 \cell +\pard\intbl\qc\fs16 71 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Cardiac disorders \cell +\pard\intbl\qc\fs16 Myocardial infarction / verbatim_1726 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell @@ -1369,21 +1347,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1218 \cell +\pard\intbl\qc\fs16 81 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Cardiac disorders \cell +\pard\intbl\qc\fs16 Angina pectoris / verbatim_1007 \cell +\pard\intbl\qc\fs16 AUG2011 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 EAR AND LABYRINTH DISORDERS \cell -\pard\intbl\qc\fs16 DEAFNESS BILATERAL / VERBATIM_0978 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1391,8 +1369,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1400,12 +1378,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 EAR AND LABYRINTH DISORDERS \cell -\pard\intbl\qc\fs16 TINNITUS / VERBATIM_0047 \cell +\pard\intbl\qc\fs16 Hepatobiliary disorders \cell +\pard\intbl\qc\fs16 Cholelithiasis / verbatim_0228 \cell +\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell \row } @@ -1413,21 +1391,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1323 \cell +\pard\intbl\qc\fs16 68 / Female / Not reported \cell +\pard\intbl\qc\fs16 Gastrointestinal disorders \cell +\pard\intbl\qc\fs16 Gastric ulcer / verbatim_0535 \cell +\pard\intbl\qc\fs16 2003 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 EYE DISORDERS \cell -\pard\intbl\qc\fs16 ASTIGMATISM / VERBATIM_1751 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -1435,8 +1413,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1444,12 +1422,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GASTROINTESTINAL DISORDERS \cell -\pard\intbl\qc\fs16 DYSPEPSIA / VERBATIM_0800 \cell +\pard\intbl\qc\fs16 Eye disorders \cell +\pard\intbl\qc\fs16 Dry eye / verbatim_0984 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1457,8 +1435,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1466,12 +1444,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 IMMUNE SYSTEM DISORDERS \cell -\pard\intbl\qc\fs16 SEASONAL ALLERGY / VERBATIM_0396 \cell +\pard\intbl\qc\fs16 Gastrointestinal disorders \cell +\pard\intbl\qc\fs16 Constipation / verbatim_0443 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1479,21 +1457,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-704-1325 \cell +\pard\intbl\qc\fs16 81 / Male / White \cell +\pard\intbl\qc\fs16 Reproductive system and breast disorders \cell +\pard\intbl\qc\fs16 Benign prostatic hyperplasia / verbatim_0255 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INFECTIONS AND INFESTATIONS \cell -\pard\intbl\qc\fs16 SINUSITIS / VERBATIM_1769 \cell -\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -1501,18 +1479,40 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1031 \cell +\pard\intbl\qc\fs16 56 / Female / Not reported \cell +\pard\intbl\qc\fs16 Vascular disorders \cell +\pard\intbl\qc\fs16 Hypertension / verbatim_0342 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 BACK PAIN / VERBATIM_1583 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1199 \cell +\pard\intbl\qc\fs16 87 / Male / Black or African American \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Hernia repair / verbatim_0722 \cell +\pard\intbl\qc\fs16 1991 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 1 \cell @@ -1523,8 +1523,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1532,12 +1532,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 MYALGIA / VERBATIM_0461 \cell +\pard\intbl\qc\fs16 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs16 Muscle spasms / verbatim_1270 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1545,21 +1545,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1393 \cell +\pard\intbl\qc\fs16 84 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Cardiac disorders \cell +\pard\intbl\qc\fs16 Bundle branch block right / verbatim_0353 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 MYALGIA / VERBATIM_1073 \cell -\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell \row } @@ -1567,21 +1567,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-705-1431 \cell +\pard\intbl\qc\fs16 68 / Female / Black or African American \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Hysterectomy / verbatim_0936 \cell +\pard\intbl\qc\fs16 1995 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 POLYARTHRITIS / VERBATIM_1168 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 4 \cell \row } @@ -1589,8 +1589,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1598,12 +1598,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 NERVOUS SYSTEM DISORDERS \cell -\pard\intbl\qc\fs16 DIZZINESS / VERBATIM_0982 \cell +\pard\intbl\qc\fs16 Eye disorders \cell +\pard\intbl\qc\fs16 Glaucoma / verbatim_0308 \cell +\pard\intbl\qc\fs16 2007 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 1 \cell \row } @@ -1611,21 +1611,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 NERVOUS SYSTEM DISORDERS \cell -\pard\intbl\qc\fs16 DIZZINESS / VERBATIM_1533 \cell +\pard\intbl\qc\fs16 01-706-1384 \cell +\pard\intbl\qc\fs16 74 / Female / Multiple \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Tumour excision / verbatim_0836 \cell +\pard\intbl\qc\fs16 1971 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell \row } @@ -1633,8 +1633,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1642,12 +1642,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 NERVOUS SYSTEM DISORDERS \cell -\pard\intbl\qc\fs16 HEADACHE / VERBATIM_0301 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Cholecystectomy / verbatim_1795 \cell +\pard\intbl\qc\fs16 1996 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -1655,8 +1655,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1664,8 +1664,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 NERVOUS SYSTEM DISORDERS \cell -\pard\intbl\qc\fs16 HYPOAESTHESIA / VERBATIM_0383 \cell +\pard\intbl\qc\fs16 Endocrine disorders \cell +\pard\intbl\qc\fs16 Hypothyroidism / verbatim_1512 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell @@ -1677,18 +1677,18 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 NERVOUS SYSTEM DISORDERS \cell -\pard\intbl\qc\fs16 HYPOAESTHESIA / VERBATIM_0617 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-707-1037 \cell +\pard\intbl\qc\fs16 72 / Female / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Reproductive system and breast disorders \cell +\pard\intbl\qc\fs16 Breast cyst / verbatim_1793 \cell +\pard\intbl\qc\fs16 1987 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 4 \cell @@ -1699,8 +1699,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1708,12 +1708,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 NERVOUS SYSTEM DISORDERS \cell -\pard\intbl\qc\fs16 HYPOAESTHESIA / VERBATIM_1576 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Infections and infestations \cell +\pard\intbl\qc\fs16 Rhinitis / verbatim_1354 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1721,8 +1721,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1730,12 +1730,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 NERVOUS SYSTEM DISORDERS \cell -\pard\intbl\qc\fs16 NEURALGIA / VERBATIM_0453 \cell +\pard\intbl\qc\fs16 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs16 Osteoarthritis / verbatim_0809 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -1743,17 +1743,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 NERVOUS SYSTEM DISORDERS \cell -\pard\intbl\qc\fs16 NEURALGIA / VERBATIM_1213 \cell +\pard\intbl\qc\fs16 01-708-1032 \cell +\pard\intbl\qc\fs16 62 / Male / Multiple \cell +\pard\intbl\qc\fs16 Infections and infestations \cell +\pard\intbl\qc\fs16 Sinusitis / verbatim_1769 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell @@ -1765,21 +1765,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1236 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Renal and urinary disorders \cell +\pard\intbl\qc\fs16 Nephrolithiasis / verbatim_0739 \cell +\pard\intbl\qc\fs16 1977 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 PSYCHIATRIC DISORDERS \cell -\pard\intbl\qc\fs16 DEPRESSED MOOD / VERBATIM_0591 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -1787,8 +1787,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1796,12 +1796,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RESPIRATORY, THORACIC AND MEDIASTINAL DISORDERS \cell -\pard\intbl\qc\fs16 DYSPNOEA / VERBATIM_1509 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Cholecystectomy / verbatim_1324 \cell +\pard\intbl\qc\fs16 1992 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -1809,21 +1809,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1180 \cell -\pard\intbl\qc\fs16 56 / M / American Indian or Alaska Native \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 / ALZHEIMER'S DISEASE \cell -\pard\intbl\qc\fs16 21SEP2008 (-1605) \cell -\pard\intbl\qc\fs16 25MAR2009 (-1420) \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 Ear and labyrinth disorders \cell +\pard\intbl\qc\fs16 Meniere's disease / verbatim_1450 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1831,8 +1831,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -1840,12 +1840,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 NERVOUS SYSTEM DISORDERS \cell -\pard\intbl\qc\fs16 HEADACHE / VERBATIM_0929 \cell +\pard\intbl\qc\fs16 Gastrointestinal disorders \cell +\pard\intbl\qc\fs16 Gastrooesophageal reflux disease / verbatim_1047 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -1853,21 +1853,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 01-701-1181 \cell -\pard\intbl\qc\fs16 79 / F / Not reported \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 TONSILLECTOMY / VERBATIM_1716 \cell -\pard\intbl\qc\fs16 1940 \cell +\pard\intbl\qc\fs16 01-708-1272 \cell +\pard\intbl\qc\fs16 82 / Male / Not reported \cell +\pard\intbl\qc\fs16 Reproductive system and breast disorders \cell +\pard\intbl\qc\fs16 Erectile dysfunction / verbatim_1211 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1875,21 +1875,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1297 \cell +\pard\intbl\qc\fs16 61 / Male / Not reported \cell +\pard\intbl\qc\fs16 Neoplasms benign, malignant and unspecified (incl cysts and polyps) \cell +\pard\intbl\qc\fs16 Lipoma / verbatim_0772 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 HYSTERECTOMY / VERBATIM_0167 \cell -\pard\intbl\qc\fs16 1967 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 2 \cell \row } @@ -1897,18 +1897,18 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs16 TOOTH EXTRACTION / VERBATIM_0204 \cell -\pard\intbl\qc\fs16 1980 \cell +\pard\intbl\qc\fs16 01-708-1348 \cell +\pard\intbl\qc\fs16 79 / Female / Multiple \cell +\pard\intbl\qc\fs16 Nervous system disorders \cell +\pard\intbl\qc\fs16 Convulsion / verbatim_0399 \cell +\pard\intbl\qc\fs16 2010 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 1 \cell @@ -1919,21 +1919,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INFECTIONS AND INFESTATIONS \cell -\pard\intbl\qc\fs16 PNEUMONIA PRIMARY ATYPICAL / VERBATIM_0124 \cell -\pard\intbl\qc\fs16 1989 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 01-708-1353 \cell +\pard\intbl\qc\fs16 87 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 06AUG2010 (-1063) \cell +\pard\intbl\qc\fs16 23AUG2011 (-681) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -1941,21 +1941,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-708-1372 \cell +\pard\intbl\qc\fs16 84 / Male / Not reported \cell +\pard\intbl\qc\fs16 General disorders and administration site conditions \cell +\pard\intbl\qc\fs16 Chest pain / verbatim_0517 \cell +\pard\intbl\qc\fs16 FEB2013 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INJURY, POISONING AND PROCEDURAL COMPLICATIONS \cell -\pard\intbl\qc\fs16 HEAD INJURY / VERBATIM_1143 \cell -\pard\intbl\qc\fs16 2006 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -1963,20 +1963,20 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INJURY, POISONING AND PROCEDURAL COMPLICATIONS \cell -\pard\intbl\qc\fs16 JOINT INJURY / VERBATIM_0192 \cell -\pard\intbl\qc\fs16 2006 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-708-1428 \cell +\pard\intbl\qc\fs16 84 / Female / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 27OCT2010 (-1109) \cell +\pard\intbl\qc\fs16 11DEC2010 (-1064) \cell +\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 4 \cell \row } @@ -1985,21 +1985,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1020 \cell +\pard\intbl\qc\fs16 72 / Female / Other \cell +\pard\intbl\qc\fs16 Surgical and medical procedures \cell +\pard\intbl\qc\fs16 Hysterectomy / verbatim_0936 \cell +\pard\intbl\qc\fs16 2003 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 / ALZHEIMER'S DISEASE \cell -\pard\intbl\qc\fs16 26AUG2008 (-1927) \cell -\pard\intbl\qc\fs16 26JAN2009 (-1774) \cell -\pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 3 \cell \row } @@ -2007,21 +2007,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-709-1081 \cell +\pard\intbl\qc\fs16 86 / Female / White \cell +\pard\intbl\qc\fs16 Eye disorders \cell +\pard\intbl\qc\fs16 Cataract / verbatim_1570 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INFECTIONS AND INFESTATIONS \cell -\pard\intbl\qc\fs16 BRONCHITIS / VERBATIM_1176 \cell -\pard\intbl\qc\fs16 2009 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -2029,21 +2029,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 RESPIRATORY, THORACIC AND MEDIASTINAL DISORDERS \cell -\pard\intbl\qc\fs16 COUGH / VERBATIM_0303 \cell -\pard\intbl\qc\fs16 08JUN2012 (-545) \cell -\pard\intbl\qc\fs16 03NOV2012 (-397) \cell +\pard\intbl\qc\fs16 01-709-1217 \cell +\pard\intbl\qc\fs16 77 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 11OCT2008 (-1605) \cell +\pard\intbl\qc\fs16 11DEC2008 (-1544) \cell \pard\intbl\qc\fs16 No \cell -\pard\intbl\qc\fs16 1 \cell +\pard\intbl\qc\fs16 5 \cell \row } @@ -2051,8 +2051,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -2060,12 +2060,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 EAR AND LABYRINTH DISORDERS \cell -\pard\intbl\qc\fs16 DEAFNESS BILATERAL / VERBATIM_0978 \cell +\pard\intbl\qc\fs16 Nervous system disorders \cell +\pard\intbl\qc\fs16 Cervicobrachial syndrome / verbatim_1718 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -2073,21 +2073,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 EYE DISORDERS \cell -\pard\intbl\qc\fs16 PRESBYOPIA / VERBATIM_0507 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 3 \cell +\pard\intbl\qc\fs16 01-709-1329 \cell +\pard\intbl\qc\fs16 70 / Male / Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 08MAR2009 (-1621) \cell +\pard\intbl\qc\fs16 14FEB2010 (-1278) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 1 \cell \row } @@ -2095,21 +2095,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 GENERAL DISORDERS AND ADMINISTRATION SITE CONDITIONS \cell -\pard\intbl\qc\fs16 OEDEMA PERIPHERAL / VERBATIM_0640 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 4 \cell +\pard\intbl\qc\fs16 01-709-1424 \cell +\pard\intbl\qc\fs16 77 / Male / Other \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 12SEP2007 (-1999) \cell +\pard\intbl\qc\fs16 24MAY2008 (-1744) \cell +\pard\intbl\qc\fs16 No \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -2117,21 +2117,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1002 \cell +\pard\intbl\qc\fs16 88 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Gastrointestinal disorders \cell +\pard\intbl\qc\fs16 Gastric ulcer / verbatim_0081 \cell +\pard\intbl\qc\fs16 1981 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INJURY, POISONING AND PROCEDURAL COMPLICATIONS \cell -\pard\intbl\qc\fs16 PAIN TRAUMA ACTIVATED / VERBATIM_0048 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -2139,21 +2139,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1045 \cell +\pard\intbl\qc\fs16 83 / Female / White \cell +\pard\intbl\qc\fs16 Investigations \cell +\pard\intbl\qc\fs16 Cardiac murmur / verbatim_0791 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INJURY, POISONING AND PROCEDURAL COMPLICATIONS \cell -\pard\intbl\qc\fs16 PAIN TRAUMA ACTIVATED / VERBATIM_0062 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 4 \cell \row } @@ -2161,20 +2161,20 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 INJURY, POISONING AND PROCEDURAL COMPLICATIONS \cell -\pard\intbl\qc\fs16 SKELETAL INJURY / VERBATIM_1215 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell +\pard\intbl\qc\fs16 01-710-1154 \cell +\pard\intbl\qc\fs16 84 / Male / American Indian or Alaska Native \cell +\pard\intbl\qc\fs16 Uncoded \cell +\pard\intbl\qc\fs16 Uncoded: alzheimer's disease / alzheimer's disease \cell +\pard\intbl\qc\fs16 25FEB2008 (-2224) \cell +\pard\intbl\qc\fs16 10JUL2008 (-2088) \cell +\pard\intbl\qc\fs16 No \cell \pard\intbl\qc\fs16 1 \cell \row } @@ -2183,8 +2183,8 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 @@ -2192,8 +2192,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 ARTHRALGIA / VERBATIM_0733 \cell +\pard\intbl\qc\fs16 Cardiac disorders \cell +\pard\intbl\qc\fs16 Bradycardia / verbatim_0125 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell @@ -2205,21 +2205,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 ARTHRALGIA / VERBATIM_1327 \cell +\pard\intbl\qc\fs16 01-710-1166 \cell +\pard\intbl\qc\fs16 81 / Female / White \cell +\pard\intbl\qc\fs16 Cardiac disorders \cell +\pard\intbl\qc\fs16 Myocardial infarction / verbatim_0075 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 5 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -2227,21 +2227,21 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6373 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3922 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7398 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9225 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10250 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11275 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12033 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc\fs16 01-710-1235 \cell +\pard\intbl\qc\fs16 56 / Female / White \cell +\pard\intbl\qc\fs16 Social circumstances \cell +\pard\intbl\qc\fs16 Walking aid user / verbatim_0360 \cell \pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS \cell -\pard\intbl\qc\fs16 FINGER DEFORMITY / VERBATIM_0966 \cell -\pard\intbl\qc\fs16 \cell \pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 \cell -\pard\intbl\qc\fs16 2 \cell +\pard\intbl\qc\fs16 3 \cell \row } @@ -2249,8 +2249,8 @@ \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx6373 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx3922 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx7398 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx9225 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx10250 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalt\cellx11275 @@ -2271,8 +2271,8 @@ \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx936 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx1516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx2318 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx6373 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx3922 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx7398 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx9225 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx10250 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalt\cellx11275 diff --git a/tests/testthat/_snaps/tirada01/tirada01.rtf b/tests/testthat/_snaps/tirada01/tirada01.rtf new file mode 100644 index 00000000..192c263b --- /dev/null +++ b/tests/testthat/_snaps/tirada01/tirada01.rtf @@ -0,0 +1,712 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2792 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6002 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9212 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRADA01:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2792 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6002 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9212 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Antibody Status \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Titer \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=168 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for antibodies to active study agent at baseline\super a\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 96 (100.0%) \cell +\pard\intbl\qc\fs18 72 (100.0%) \cell +\pard\intbl\qc\fs18 168 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline titers \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:20 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:40 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:80 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:160 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:320 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:640 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:1280 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for antibodies to active study agent at baseline who were treatment-boosted for antibodies to active study agent\super b\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 96 (100.0%) \cell +\pard\intbl\qc\fs18 72 (100.0%) \cell +\pard\intbl\qc\fs18 168 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline titers \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:20 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 25 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:40 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:80 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:160 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 14 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:320 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 25 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:640 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:1280 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for antibodies to active study agent at baseline who were not treatment-boosted for antibodies to active study agent\super c\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 96 (100.0%) \cell +\pard\intbl\qc\fs18 72 (100.0%) \cell +\pard\intbl\qc\fs18 168 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline titers \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:20 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 26 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:40 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:80 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:160 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:320 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 14 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:640 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 17 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:1280 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 23 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for treatment-induced antibodies to active study agent\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 96 (100.0%) \cell +\pard\intbl\qc\fs18 72 (100.0%) \cell +\pard\intbl\qc\fs18 168 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Peak titers \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:20 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 13 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:40 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 25 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:80 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:160 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:320 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:640 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:1280 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for treatment-emergent antibodies to active study agent\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 35 (36.5%) \cell +\pard\intbl\qc\fs18 26 (36.1%) \cell +\pard\intbl\qc\fs18 61 (36.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Peak titers \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:10 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:160 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1:1280 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 91 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Peak titer group\super f\nosupersub \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 <10 \cell +\pard\intbl\qc\fs18 8 (22.9%) \cell +\pard\intbl\qc\fs18 10 (38.5%) \cell +\pard\intbl\qc\fs18 18 (29.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 10 to <100 \cell +\pard\intbl\qc\fs18 10 (28.6%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\pard\intbl\qc\fs18 12 (19.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 100 to <1000 \cell +\pard\intbl\qc\fs18 10 (28.6%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\pard\intbl\qc\fs18 13 (21.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?1000 \cell +\pard\intbl\qc\fs18 7 (20.0%) \cell +\pard\intbl\qc\fs18 11 (42.3%) \cell +\pard\intbl\qc\fs18 18 (29.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects negative for treatment-emergent antibodies to active study agent\super g\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 61 (63.5%) \cell +\pard\intbl\qc\fs18 46 (63.9%) \cell +\pard\intbl\qc\fs18 107 (63.7%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2792 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6002 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9212 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirada02/tirada02.rtf b/tests/testthat/_snaps/tirada02/tirada02.rtf new file mode 100644 index 00000000..d7c317b3 --- /dev/null +++ b/tests/testthat/_snaps/tirada02/tirada02.rtf @@ -0,0 +1,280 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRADA02:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with evaluable samples\super a\nosupersub \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for treatment-emergent antibodies to active study agent\super b,d\nosupersub \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 9 (39.1%) \cell +\pard\intbl\qc\fs18 11 (61.1%) \cell +\pard\intbl\qc\fs18 20 (48.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with severe infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with serious infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 7 (30.4%) \cell +\pard\intbl\qc\fs18 7 (38.9%) \cell +\pard\intbl\qc\fs18 14 (34.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion-related reaction leading to treatment discontinuation, n (%) \cell +\pard\intbl\qc\fs18 1 (4.3%) \cell +\pard\intbl\qc\fs18 3 (16.7%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of active study agent infusions \cell +\pard\intbl\qc\fs18 275 \cell +\pard\intbl\qc\fs18 257 \cell +\pard\intbl\qc\fs18 532 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusions with infusion-related reactions\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 11 (4.0%) \cell +\pard\intbl\qc\fs18 17 (6.6%) \cell +\pard\intbl\qc\fs18 28 (5.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects negative for treatment-emergent antibodies to active study agent\super c,d\nosupersub \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 77 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 18 (40.9%) \cell +\pard\intbl\qc\fs18 13 (39.4%) \cell +\pard\intbl\qc\fs18 31 (40.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with severe infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 4 (9.1%) \cell +\pard\intbl\qc\fs18 6 (18.2%) \cell +\pard\intbl\qc\fs18 10 (13.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with serious infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 11 (25.0%) \cell +\pard\intbl\qc\fs18 10 (30.3%) \cell +\pard\intbl\qc\fs18 21 (27.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion-related reaction leading to treatment discontinuation, n (%) \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 3 (9.1%) \cell +\pard\intbl\qc\fs18 5 (6.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of active study agent infusions \cell +\pard\intbl\qc\fs18 669 \cell +\pard\intbl\qc\fs18 442 \cell +\pard\intbl\qc\fs18 1111 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusions with infusion-related reactions\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 17 (2.5%) \cell +\pard\intbl\qc\fs18 18 (4.1%) \cell +\pard\intbl\qc\fs18 35 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirada02b/tirada02b.rtf b/tests/testthat/_snaps/tirada02b/tirada02b.rtf new file mode 100644 index 00000000..b4462977 --- /dev/null +++ b/tests/testthat/_snaps/tirada02b/tirada02b.rtf @@ -0,0 +1,280 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRADA02b:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with evaluable samples\super a\nosupersub \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for treatment-emergent antibodies to active study agent\super b,d\nosupersub \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion site reaction, n (%) \cell +\pard\intbl\qc\fs18 7 (30.4%) \cell +\pard\intbl\qc\fs18 11 (61.1%) \cell +\pard\intbl\qc\fs18 18 (43.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with severe infusion site reaction, n (%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with serious infusion site reaction, n (%) \cell +\pard\intbl\qc\fs18 5 (21.7%) \cell +\pard\intbl\qc\fs18 8 (44.4%) \cell +\pard\intbl\qc\fs18 13 (31.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion site reaction leading to treatment discontinuation, n (%) \cell +\pard\intbl\qc\fs18 1 (4.3%) \cell +\pard\intbl\qc\fs18 1 (5.6%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of active study agent infusions \cell +\pard\intbl\qc\fs18 275 \cell +\pard\intbl\qc\fs18 257 \cell +\pard\intbl\qc\fs18 532 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusions with infusion site reactions\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 7 (2.5%) \cell +\pard\intbl\qc\fs18 12 (4.7%) \cell +\pard\intbl\qc\fs18 19 (3.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects negative for treatment-emergent antibodies to active study agent\super c,d\nosupersub \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 77 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion site reaction, n (%) \cell +\pard\intbl\qc\fs18 19 (43.2%) \cell +\pard\intbl\qc\fs18 14 (42.4%) \cell +\pard\intbl\qc\fs18 33 (42.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with severe infusion site reaction, n (%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with serious infusion site reaction, n (%) \cell +\pard\intbl\qc\fs18 9 (20.5%) \cell +\pard\intbl\qc\fs18 9 (27.3%) \cell +\pard\intbl\qc\fs18 18 (23.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion site reaction leading to treatment discontinuation, n (%) \cell +\pard\intbl\qc\fs18 6 (13.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of active study agent infusions \cell +\pard\intbl\qc\fs18 669 \cell +\pard\intbl\qc\fs18 442 \cell +\pard\intbl\qc\fs18 1111 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusions with infusion site reactions\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 22 (3.3%) \cell +\pard\intbl\qc\fs18 18 (4.1%) \cell +\pard\intbl\qc\fs18 40 (3.6%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirada02btiter/tirada02btiter.rtf b/tests/testthat/_snaps/tirada02btiter/tirada02btiter.rtf new file mode 100644 index 00000000..1d0fdf97 --- /dev/null +++ b/tests/testthat/_snaps/tirada02btiter/tirada02btiter.rtf @@ -0,0 +1,256 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRADA02b_titer:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Negative for Treatment-emergent Antibodies to active study agent\super a\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr Positive for Treatment-emergent Antibodies to active study agent\super b\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr <10 \cell +\pard\intbl\qc\fs18 \keepn\trhdr 10 to <100 \cell +\pard\intbl\qc\fs18 \keepn\trhdr 100 to <1000 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805?1000 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=110 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=32 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=41 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=56 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with evaluable samples\super c\nosupersub \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion site reaction\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 44 (40.0%) \cell +\pard\intbl\qc\fs18 27 (37.5%) \cell +\pard\intbl\qc\fs18 19 (35.8%) \cell +\pard\intbl\qc\fs18 13 (40.6%) \cell +\pard\intbl\qc\fs18 19 (46.3%) \cell +\pard\intbl\qc\fs18 20 (35.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with severe infusion site reaction\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 1 (0.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with serious infusion site reaction\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 23 (20.9%) \cell +\pard\intbl\qc\fs18 19 (26.4%) \cell +\pard\intbl\qc\fs18 11 (20.8%) \cell +\pard\intbl\qc\fs18 8 (25.0%) \cell +\pard\intbl\qc\fs18 11 (26.8%) \cell +\pard\intbl\qc\fs18 12 (21.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion site reaction leading to treatment discontinuation\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 8 (7.3%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 3 (9.4%) \cell +\pard\intbl\qc\fs18 6 (14.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of active study agent infusions \cell +\pard\intbl\qc\fs18 1577 \cell +\pard\intbl\qc\fs18 952 \cell +\pard\intbl\qc\fs18 734 \cell +\pard\intbl\qc\fs18 412 \cell +\pard\intbl\qc\fs18 626 \cell +\pard\intbl\qc\fs18 757 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusions with infusion site reactions\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 50 (3.2%) \cell +\pard\intbl\qc\fs18 27 (2.8%) \cell +\pard\intbl\qc\fs18 21 (2.9%) \cell +\pard\intbl\qc\fs18 15 (3.6%) \cell +\pard\intbl\qc\fs18 20 (3.2%) \cell +\pard\intbl\qc\fs18 21 (2.8%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirada02titer/tirada02titer.rtf b/tests/testthat/_snaps/tirada02titer/tirada02titer.rtf new file mode 100644 index 00000000..fdf5efb2 --- /dev/null +++ b/tests/testthat/_snaps/tirada02titer/tirada02titer.rtf @@ -0,0 +1,256 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRADA02titer:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Negative for Treatment-emergent Antibodies to active study agent\super a\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr Positive for Treatment-emergent Antibodies to active study agent\super b\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr <10 \cell +\pard\intbl\qc\fs18 \keepn\trhdr 10 to <100 \cell +\pard\intbl\qc\fs18 \keepn\trhdr 100 to <1000 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805?1000 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=110 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=32 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=41 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=56 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with evaluable samples\super c\nosupersub \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion-related reaction\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 43 (39.1%) \cell +\pard\intbl\qc\fs18 28 (38.9%) \cell +\pard\intbl\qc\fs18 15 (28.3%) \cell +\pard\intbl\qc\fs18 12 (37.5%) \cell +\pard\intbl\qc\fs18 16 (39.0%) \cell +\pard\intbl\qc\fs18 28 (50.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with severe infusion-related reaction\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 13 (11.8%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 3 (9.4%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 6 (10.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with serious infusion-related reaction\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 29 (26.4%) \cell +\pard\intbl\qc\fs18 19 (26.4%) \cell +\pard\intbl\qc\fs18 9 (17.0%) \cell +\pard\intbl\qc\fs18 8 (25.0%) \cell +\pard\intbl\qc\fs18 9 (22.0%) \cell +\pard\intbl\qc\fs18 22 (39.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with infusion-related reaction leading to treatment discontinuation\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 6 (5.5%) \cell +\pard\intbl\qc\fs18 5 (6.9%) \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 1 (3.1%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 6 (10.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of active study agent infusions \cell +\pard\intbl\qc\fs18 1577 \cell +\pard\intbl\qc\fs18 952 \cell +\pard\intbl\qc\fs18 734 \cell +\pard\intbl\qc\fs18 412 \cell +\pard\intbl\qc\fs18 626 \cell +\pard\intbl\qc\fs18 757 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusions with infusion-related reactions\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 48 (3.0%) \cell +\pard\intbl\qc\fs18 34 (3.6%) \cell +\pard\intbl\qc\fs18 18 (2.5%) \cell +\pard\intbl\qc\fs18 13 (3.2%) \cell +\pard\intbl\qc\fs18 16 (2.6%) \cell +\pard\intbl\qc\fs18 35 (4.6%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirada03/tirada03.rtf b/tests/testthat/_snaps/tirada03/tirada03.rtf new file mode 100644 index 00000000..c5adc551 --- /dev/null +++ b/tests/testthat/_snaps/tirada03/tirada03.rtf @@ -0,0 +1,280 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRADA03:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with evaluable samples\super a\nosupersub \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for treatment-emergent antibodies to active study agent\super b,d\nosupersub \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 10 (43.5%) \cell +\pard\intbl\qc\fs18 8 (44.4%) \cell +\pard\intbl\qc\fs18 18 (43.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with severe injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.6%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with serious injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 10 (43.5%) \cell +\pard\intbl\qc\fs18 5 (27.8%) \cell +\pard\intbl\qc\fs18 15 (36.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with injection site reaction leading to treatment discontinuation, n (%) \cell +\pard\intbl\qc\fs18 3 (13.0%) \cell +\pard\intbl\qc\fs18 2 (11.1%) \cell +\pard\intbl\qc\fs18 5 (12.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of active study agent injections \cell +\pard\intbl\qc\fs18 275 \cell +\pard\intbl\qc\fs18 257 \cell +\pard\intbl\qc\fs18 532 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Injections with injection site reactions\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 11 (4.0%) \cell +\pard\intbl\qc\fs18 8 (3.1%) \cell +\pard\intbl\qc\fs18 19 (3.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects negative for treatment-emergent antibodies to active study agent\super c,d\nosupersub \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 77 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 13 (29.5%) \cell +\pard\intbl\qc\fs18 19 (57.6%) \cell +\pard\intbl\qc\fs18 32 (41.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with severe injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with serious injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 8 (18.2%) \cell +\pard\intbl\qc\fs18 13 (39.4%) \cell +\pard\intbl\qc\fs18 21 (27.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with injection site reaction leading to treatment discontinuation, n (%) \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 6 (18.2%) \cell +\pard\intbl\qc\fs18 8 (10.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of active study agent injections \cell +\pard\intbl\qc\fs18 669 \cell +\pard\intbl\qc\fs18 442 \cell +\pard\intbl\qc\fs18 1111 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Injections with injection site reactions\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 14 (2.1%) \cell +\pard\intbl\qc\fs18 20 (4.5%) \cell +\pard\intbl\qc\fs18 34 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirada03titer/tirada03titer.rtf b/tests/testthat/_snaps/tirada03titer/tirada03titer.rtf new file mode 100644 index 00000000..c941b124 --- /dev/null +++ b/tests/testthat/_snaps/tirada03titer/tirada03titer.rtf @@ -0,0 +1,256 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRADA03titer:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to active study agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Negative for Treatment-emergent Antibodies to active study agent\super a\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr Positive for Treatment-emergent Antibodies to active study agent\super b\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr <10 \cell +\pard\intbl\qc\fs18 \keepn\trhdr 10 to <100 \cell +\pard\intbl\qc\fs18 \keepn\trhdr 100 to <1000 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805?1000 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=110 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=32 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=41 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=56 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with evaluable samples\super c\nosupersub \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with injection site reaction\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 38 (34.5%) \cell +\pard\intbl\qc\fs18 25 (34.7%) \cell +\pard\intbl\qc\fs18 21 (39.6%) \cell +\pard\intbl\qc\fs18 10 (31.3%) \cell +\pard\intbl\qc\fs18 16 (39.0%) \cell +\pard\intbl\qc\fs18 16 (28.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with severe injection site reaction\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 1 (0.9%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with serious injection site reaction\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 25 (22.7%) \cell +\pard\intbl\qc\fs18 18 (25.0%) \cell +\pard\intbl\qc\fs18 12 (22.6%) \cell +\pard\intbl\qc\fs18 8 (25.0%) \cell +\pard\intbl\qc\fs18 12 (29.3%) \cell +\pard\intbl\qc\fs18 11 (19.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with injection site reaction leading to treatment discontinuation\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 9 (8.2%) \cell +\pard\intbl\qc\fs18 6 (8.3%) \cell +\pard\intbl\qc\fs18 7 (13.2%) \cell +\pard\intbl\qc\fs18 2 (6.3%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 3 (5.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of active study agent injections \cell +\pard\intbl\qc\fs18 1577 \cell +\pard\intbl\qc\fs18 952 \cell +\pard\intbl\qc\fs18 734 \cell +\pard\intbl\qc\fs18 412 \cell +\pard\intbl\qc\fs18 626 \cell +\pard\intbl\qc\fs18 757 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Injections with injection site reactions\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 41 (2.6%) \cell +\pard\intbl\qc\fs18 25 (2.6%) \cell +\pard\intbl\qc\fs18 21 (2.9%) \cell +\pard\intbl\qc\fs18 10 (2.4%) \cell +\pard\intbl\qc\fs18 19 (3.0%) \cell +\pard\intbl\qc\fs18 16 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirada06/tirada06.rtf b/tests/testthat/_snaps/tirada06/tirada06.rtf new file mode 100644 index 00000000..9d7dcb6f --- /dev/null +++ b/tests/testthat/_snaps/tirada06/tirada06.rtf @@ -0,0 +1,412 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6139 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9420 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRADA06:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2858 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6139 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9420 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=168 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for treatment-induced antibodies to active study agent\super a\nosupersub \cell +\pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell +\pard\intbl\qc\fs18 168 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with persistent ADA response\super b\nosupersub \cell +\pard\intbl\qc\fs18 96 (100.0%) \cell +\pard\intbl\qc\fs18 72 (100.0%) \cell +\pard\intbl\qc\fs18 168 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with transient ADA response\super c\nosupersub \cell +\pard\intbl\qc\fs18 96 (100.0%) \cell +\pard\intbl\qc\fs18 72 (100.0%) \cell +\pard\intbl\qc\fs18 168 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with undetermined ADA response\super d\nosupersub \cell +\pard\intbl\qc\fs18 96 (100.0%) \cell +\pard\intbl\qc\fs18 72 (100.0%) \cell +\pard\intbl\qc\fs18 168 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Time to onset of treatment-induced ADA\super e\nosupersub , (weeks) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell +\pard\intbl\qc\fs18 168 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 472.19 (469.075) \cell +\pard\intbl\qc\fs18 475.25 (472.434) \cell +\pard\intbl\qc\fs18 473.50 (469.106) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 98.00 \cell +\pard\intbl\qc\fs18 97.50 \cell +\pard\intbl\qc\fs18 98.00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 1.0, 1009.0 \cell +\pard\intbl\qc\fs18 1.0, 1009.0 \cell +\pard\intbl\qc\fs18 1.0, 1009.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 99.34 \cell +\pard\intbl\qc\fs18 99.41 \cell +\pard\intbl\qc\fs18 99.07 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 91.50, 998.00 \cell +\pard\intbl\qc\fs18 91.00, 996.00 \cell +\pard\intbl\qc\fs18 91.00, 996.00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Duration of treatment-induced ADA\super f\nosupersub , (weeks) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell +\pard\intbl\qc\fs18 168 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 443.71 (473.754) \cell +\pard\intbl\qc\fs18 510.88 (480.095) \cell +\pard\intbl\qc\fs18 472.49 (476.216) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 96.00 \cell +\pard\intbl\qc\fs18 98.00 \cell +\pard\intbl\qc\fs18 97.00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 1.0, 1009.0 \cell +\pard\intbl\qc\fs18 1.0, 1009.0 \cell +\pard\intbl\qc\fs18 1.0, 1009.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 106.77 \cell +\pard\intbl\qc\fs18 93.97 \cell +\pard\intbl\qc\fs18 100.79 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 7.00, 998.00 \cell +\pard\intbl\qc\fs18 8.50, 998.00 \cell +\pard\intbl\qc\fs18 7.00, 998.00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Duration of persistent treatment-induced ADA\super b,f\nosupersub , (weeks) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell +\pard\intbl\qc\fs18 168 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 533.56 (479.634) \cell +\pard\intbl\qc\fs18 512.96 (479.245) \cell +\pard\intbl\qc\fs18 524.73 (478.139) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 992.00 \cell +\pard\intbl\qc\fs18 99.00 \cell +\pard\intbl\qc\fs18 545.50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 1.0, 1008.0 \cell +\pard\intbl\qc\fs18 1.0, 1009.0 \cell +\pard\intbl\qc\fs18 1.0, 1009.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 89.89 \cell +\pard\intbl\qc\fs18 93.43 \cell +\pard\intbl\qc\fs18 91.12 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 9.00, 1001.00 \cell +\pard\intbl\qc\fs18 50.00, 1002.50 \cell +\pard\intbl\qc\fs18 9.00, 1001.50 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6139 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9420 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirada07/tirada07.rtf b/tests/testthat/_snaps/tirada07/tirada07.rtf new file mode 100644 index 00000000..564e2b3c --- /dev/null +++ b/tests/testthat/_snaps/tirada07/tirada07.rtf @@ -0,0 +1,208 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2792 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6002 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9212 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRADA07:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2792 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6002 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9212 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Visit \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=168 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for treatment-emergent antibodies to active study agent\super a\nosupersub \cell +\pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell +\pard\intbl\qc\fs18 168 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - Pre-dose \cell +\pard\intbl\qc\fs18 1/62 (1.6%) \cell +\pard\intbl\qc\fs18 2/54 (3.7%) \cell +\pard\intbl\qc\fs18 3/116 (2.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - Dose \cell +\pard\intbl\qc\fs18 0/57 \cell +\pard\intbl\qc\fs18 1/53 (1.9%) \cell +\pard\intbl\qc\fs18 1/110 (0.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 8h Post-dose \cell +\pard\intbl\qc\fs18 3/61 (4.9%) \cell +\pard\intbl\qc\fs18 1/52 (1.9%) \cell +\pard\intbl\qc\fs18 4/113 (3.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - Pre-dose \cell +\pard\intbl\qc\fs18 1/60 (1.7%) \cell +\pard\intbl\qc\fs18 1/52 (1.9%) \cell +\pard\intbl\qc\fs18 2/112 (1.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - Dose \cell +\pard\intbl\qc\fs18 0/57 \cell +\pard\intbl\qc\fs18 0/52 \cell +\pard\intbl\qc\fs18 0/109 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 8h Post-dose \cell +\pard\intbl\qc\fs18 1/60 (1.7%) \cell +\pard\intbl\qc\fs18 2/54 (3.7%) \cell +\pard\intbl\qc\fs18 3/114 (2.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - Pre-dose \cell +\pard\intbl\qc\fs18 0/61 \cell +\pard\intbl\qc\fs18 1/53 (1.9%) \cell +\pard\intbl\qc\fs18 1/114 (0.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - Dose \cell +\pard\intbl\qc\fs18 2/63 (3.2%) \cell +\pard\intbl\qc\fs18 1/52 (1.9%) \cell +\pard\intbl\qc\fs18 3/115 (2.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2792 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6002 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9212 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - 8h Post-dose \cell +\pard\intbl\qc\fs18 2/60 (3.3%) \cell +\pard\intbl\qc\fs18 1/52 (1.9%) \cell +\pard\intbl\qc\fs18 3/112 (2.7%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2792 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6002 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9212 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2792 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6002 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9212 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirnab01/tirnab01.rtf b/tests/testthat/_snaps/tirnab01/tirnab01.rtf new file mode 100644 index 00000000..21950121 --- /dev/null +++ b/tests/testthat/_snaps/tirnab01/tirnab01.rtf @@ -0,0 +1,160 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRNAB01:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr NAb Status \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=168 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for treatment-emergent antibodies to active study agent at any time\super a\nosupersub \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects evaluable for neutralizing antibodies\super b\nosupersub \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects positive for neutralizing antibodies\super c\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 16 (45.7%) \cell +\pard\intbl\qc\fs18 13 (50.0%) \cell +\pard\intbl\qc\fs18 29 (47.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects negative for neutralizing antibodies\super d\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 19 (54.3%) \cell +\pard\intbl\qc\fs18 13 (50.0%) \cell +\pard\intbl\qc\fs18 32 (52.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Overall incidence of subjects positive for neutralizing antibodies\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 16 (16.7%) \cell +\pard\intbl\qc\fs18 13 (18.1%) \cell +\pard\intbl\qc\fs18 29 (17.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Overall incidence of subjects negative for neutralizing antibodies\super e\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 19 (19.8%) \cell +\pard\intbl\qc\fs18 13 (18.1%) \cell +\pard\intbl\qc\fs18 32 (19.0%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirnab02/tirnab02.rtf b/tests/testthat/_snaps/tirnab02/tirnab02.rtf new file mode 100644 index 00000000..f7b1de6b --- /dev/null +++ b/tests/testthat/_snaps/tirnab02/tirnab02.rtf @@ -0,0 +1,292 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRNAB02:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for treatment-emergent antibodies to active study agent at any time\super a\nosupersub \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects evaluable for neutralizing antibodies \super b\nosupersub \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects positive for neutralizing antibodies to active study agent \super c,e\nosupersub \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 11 (39.3%) \cell +\pard\intbl\qc\fs18 13 (52.0%) \cell +\pard\intbl\qc\fs18 24 (45.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with severe infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 2 (7.1%) \cell +\pard\intbl\qc\fs18 3 (12.0%) \cell +\pard\intbl\qc\fs18 5 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with serious infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 9 (32.1%) \cell +\pard\intbl\qc\fs18 11 (44.0%) \cell +\pard\intbl\qc\fs18 20 (37.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with infusion-related reaction leading to treatment discontinuation, n (%) \cell +\pard\intbl\qc\fs18 2 (7.1%) \cell +\pard\intbl\qc\fs18 3 (12.0%) \cell +\pard\intbl\qc\fs18 5 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Total number of active study agent infusions \cell +\pard\intbl\qc\fs18 146 \cell +\pard\intbl\qc\fs18 159 \cell +\pard\intbl\qc\fs18 305 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Infusions with infusion-related reactions\super f\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 11 (7.5%) \cell +\pard\intbl\qc\fs18 17 (10.7%) \cell +\pard\intbl\qc\fs18 28 (9.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects negative for neutralizing antibodies to active study agent \super d,e\nosupersub \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 16 (41.0%) \cell +\pard\intbl\qc\fs18 11 (42.3%) \cell +\pard\intbl\qc\fs18 27 (41.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with severe infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\pard\intbl\qc\fs18 5 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with serious infusion-related reaction, n (%) \cell +\pard\intbl\qc\fs18 9 (23.1%) \cell +\pard\intbl\qc\fs18 6 (23.1%) \cell +\pard\intbl\qc\fs18 15 (23.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with infusion-related reaction leading to treatment discontinuation, n (%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\pard\intbl\qc\fs18 4 (6.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Total number of active study agent infusions \cell +\pard\intbl\qc\fs18 219 \cell +\pard\intbl\qc\fs18 148 \cell +\pard\intbl\qc\fs18 367 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Infusions with infusion-related reactions\super f\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 17 (7.8%) \cell +\pard\intbl\qc\fs18 18 (12.2%) \cell +\pard\intbl\qc\fs18 35 (9.5%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tirnab03/tirnab03.rtf b/tests/testthat/_snaps/tirnab03/tirnab03.rtf new file mode 100644 index 00000000..1e34b271 --- /dev/null +++ b/tests/testthat/_snaps/tirnab03/tirnab03.rtf @@ -0,0 +1,292 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TIRNAB03:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects positive for treatment-emergent antibodies to active study agent at any time\super a\nosupersub \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects evaluable for neutralizing antibodies \super b\nosupersub \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects positive for neutralizing antibodies to active study agent \super c,e\nosupersub \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 8 (28.6%) \cell +\pard\intbl\qc\fs18 14 (56.0%) \cell +\pard\intbl\qc\fs18 22 (41.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with severe injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (4.0%) \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with serious injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 7 (25.0%) \cell +\pard\intbl\qc\fs18 10 (40.0%) \cell +\pard\intbl\qc\fs18 17 (32.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with injection site reaction leading to treatment discontinuation, n (%) \cell +\pard\intbl\qc\fs18 2 (7.1%) \cell +\pard\intbl\qc\fs18 5 (20.0%) \cell +\pard\intbl\qc\fs18 7 (13.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Total number of active study agent injections \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 171 \cell +\pard\intbl\qc\fs18 249 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Injections with injection site reactions\super f\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 9 (11.5%) \cell +\pard\intbl\qc\fs18 14 (8.2%) \cell +\pard\intbl\qc\fs18 23 (9.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects negative for neutralizing antibodies to active study agent \super d,e\nosupersub \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 15 (38.5%) \cell +\pard\intbl\qc\fs18 13 (50.0%) \cell +\pard\intbl\qc\fs18 28 (43.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with severe injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with serious injection site reaction, n (%) \cell +\pard\intbl\qc\fs18 11 (28.2%) \cell +\pard\intbl\qc\fs18 8 (30.8%) \cell +\pard\intbl\qc\fs18 19 (29.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subjects with injection site reaction leading to treatment discontinuation, n (%) \cell +\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\pard\intbl\qc\fs18 6 (9.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Total number of active study agent injections \cell +\pard\intbl\qc\fs18 160 \cell +\pard\intbl\qc\fs18 179 \cell +\pard\intbl\qc\fs18 339 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Injections with injection site reactions\super f\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 16 (10.0%) \cell +\pard\intbl\qc\fs18 14 (7.8%) \cell +\pard\intbl\qc\fs18 30 (8.8%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tpk01a/tpk01a.rtf b/tests/testthat/_snaps/tpk01a/tpk01a.rtf index d958d14e..326544e2 100644 --- a/tests/testthat/_snaps/tpk01a/tpk01a.rtf +++ b/tests/testthat/_snaps/tpk01a/tpk01a.rtf @@ -3,9 +3,9 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2849 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4962 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7076 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2845 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4960 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7074 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TPK01a:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -15,9 +15,9 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2849 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4962 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7076 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2845 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4960 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7074 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -27,34 +27,34 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell \pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell \pard\intbl\qc\fs18 \keepn\trhdr N=168 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - Pre-dose \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, Pre-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -63,45 +63,45 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell \pard\intbl\qc\fs18 NA \cell \pard\intbl\qc\fs18 NA \cell @@ -111,21 +111,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell \pard\intbl\qc\fs18 NA \cell \pard\intbl\qc\fs18 NA \cell @@ -135,21 +135,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -159,10 +159,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 5 Min Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 5 Min Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -171,93 +171,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.10 (0.00) \cell -\pard\intbl\qc\fs18 0.10 (0.01) \cell -\pard\intbl\qc\fs18 0.10 (0.01) \cell +\pard\intbl\qc\fs18 0.101 (0.00531) \cell +\pard\intbl\qc\fs18 0.100 (0.00489) \cell +\pard\intbl\qc\fs18 0.101 (0.00513) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell +\pard\intbl\qc\fs18 0.100 \cell +\pard\intbl\qc\fs18 0.100 \cell +\pard\intbl\qc\fs18 0.100 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell +\pard\intbl\qc\fs18 0.101 \cell +\pard\intbl\qc\fs18 0.100 \cell +\pard\intbl\qc\fs18 0.100 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.09, 0.11 \cell -\pard\intbl\qc\fs18 0.09, 0.11 \cell -\pard\intbl\qc\fs18 0.09, 0.11 \cell +\pard\intbl\qc\fs18 (0.0906, 0.111) \cell +\pard\intbl\qc\fs18 (0.0912, 0.112) \cell +\pard\intbl\qc\fs18 (0.0906, 0.112) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 4.9 \cell \pard\intbl\qc\fs18 5.3 \cell +\pard\intbl\qc\fs18 4.9 \cell \pard\intbl\qc\fs18 5.1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.10, 0.10 \cell -\pard\intbl\qc\fs18 0.10, 0.10 \cell -\pard\intbl\qc\fs18 0.10, 0.10 \cell +\pard\intbl\qc\fs18 (0.0967, 0.105) \cell +\pard\intbl\qc\fs18 (0.0960, 0.103) \cell +\pard\intbl\qc\fs18 (0.0963, 0.104) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -267,10 +267,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 30 Min Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 30 Min Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -279,93 +279,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.54 (0.02) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell +\pard\intbl\qc\fs18 0.546 (0.0263) \cell +\pard\intbl\qc\fs18 0.544 (0.0241) \cell +\pard\intbl\qc\fs18 0.545 (0.0253) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.54 \cell +\pard\intbl\qc\fs18 0.544 \cell +\pard\intbl\qc\fs18 0.543 \cell +\pard\intbl\qc\fs18 0.544 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.54 \cell +\pard\intbl\qc\fs18 0.545 \cell +\pard\intbl\qc\fs18 0.543 \cell +\pard\intbl\qc\fs18 0.544 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.50, 0.60 \cell -\pard\intbl\qc\fs18 0.50, 0.60 \cell -\pard\intbl\qc\fs18 0.50, 0.60 \cell +\pard\intbl\qc\fs18 (0.495, 0.597) \cell +\pard\intbl\qc\fs18 (0.499, 0.603) \cell +\pard\intbl\qc\fs18 (0.495, 0.603) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 4.4 \cell \pard\intbl\qc\fs18 4.8 \cell +\pard\intbl\qc\fs18 4.4 \cell \pard\intbl\qc\fs18 4.6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.52, 0.56 \cell -\pard\intbl\qc\fs18 0.53, 0.57 \cell -\pard\intbl\qc\fs18 0.52, 0.56 \cell +\pard\intbl\qc\fs18 (0.527, 0.567) \cell +\pard\intbl\qc\fs18 (0.524, 0.557) \cell +\pard\intbl\qc\fs18 (0.525, 0.563) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -375,10 +375,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 1h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -387,93 +387,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.93 (0.04) \cell -\pard\intbl\qc\fs18 0.93 (0.04) \cell -\pard\intbl\qc\fs18 0.93 (0.04) \cell +\pard\intbl\qc\fs18 0.931 (0.0406) \cell +\pard\intbl\qc\fs18 0.927 (0.0370) \cell +\pard\intbl\qc\fs18 0.929 (0.0391) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.93 \cell +\pard\intbl\qc\fs18 0.927 \cell +\pard\intbl\qc\fs18 0.926 \cell +\pard\intbl\qc\fs18 0.926 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.93 \cell +\pard\intbl\qc\fs18 0.930 \cell +\pard\intbl\qc\fs18 0.926 \cell +\pard\intbl\qc\fs18 0.928 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.86, 1.02 \cell -\pard\intbl\qc\fs18 0.85, 1.01 \cell -\pard\intbl\qc\fs18 0.85, 1.02 \cell +\pard\intbl\qc\fs18 (0.852, 1.01) \cell +\pard\intbl\qc\fs18 (0.859, 1.02) \cell +\pard\intbl\qc\fs18 (0.852, 1.02) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 4.0 \cell \pard\intbl\qc\fs18 4.4 \cell +\pard\intbl\qc\fs18 4.0 \cell \pard\intbl\qc\fs18 4.2 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.90, 0.95 \cell -\pard\intbl\qc\fs18 0.90, 0.96 \cell -\pard\intbl\qc\fs18 0.90, 0.96 \cell +\pard\intbl\qc\fs18 (0.900, 0.962) \cell +\pard\intbl\qc\fs18 (0.899, 0.949) \cell +\pard\intbl\qc\fs18 (0.899, 0.958) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -483,10 +483,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1.5h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 1.5h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -495,33 +495,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.20 (0.04) \cell -\pard\intbl\qc\fs18 1.20 (0.05) \cell -\pard\intbl\qc\fs18 1.20 (0.05) \cell +\pard\intbl\qc\fs18 1.20 (0.0481) \cell +\pard\intbl\qc\fs18 1.20 (0.0438) \cell +\pard\intbl\qc\fs18 1.20 (0.0462) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell \pard\intbl\qc\fs18 1.20 \cell \pard\intbl\qc\fs18 1.20 \cell @@ -531,9 +531,9 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell \pard\intbl\qc\fs18 1.20 \cell \pard\intbl\qc\fs18 1.20 \cell @@ -543,45 +543,45 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.12, 1.31 \cell -\pard\intbl\qc\fs18 1.11, 1.29 \cell -\pard\intbl\qc\fs18 1.11, 1.31 \cell +\pard\intbl\qc\fs18 (1.11, 1.29) \cell +\pard\intbl\qc\fs18 (1.12, 1.31) \cell +\pard\intbl\qc\fs18 (1.11, 1.31) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 3.7 \cell \pard\intbl\qc\fs18 4.0 \cell +\pard\intbl\qc\fs18 3.7 \cell \pard\intbl\qc\fs18 3.9 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.17, 1.22 \cell -\pard\intbl\qc\fs18 1.16, 1.24 \cell -\pard\intbl\qc\fs18 1.17, 1.23 \cell +\pard\intbl\qc\fs18 (1.16, 1.24) \cell +\pard\intbl\qc\fs18 (1.17, 1.22) \cell +\pard\intbl\qc\fs18 (1.17, 1.23) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -591,10 +591,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 2h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 2h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -603,45 +603,45 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.39 (0.05) \cell -\pard\intbl\qc\fs18 1.39 (0.05) \cell -\pard\intbl\qc\fs18 1.39 (0.05) \cell +\pard\intbl\qc\fs18 1.39 (0.0518) \cell +\pard\intbl\qc\fs18 1.39 (0.0474) \cell +\pard\intbl\qc\fs18 1.39 (0.0499) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.38 \cell \pard\intbl\qc\fs18 1.39 \cell +\pard\intbl\qc\fs18 1.38 \cell \pard\intbl\qc\fs18 1.39 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell \pard\intbl\qc\fs18 1.39 \cell \pard\intbl\qc\fs18 1.39 \cell @@ -651,45 +651,45 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.31, 1.50 \cell -\pard\intbl\qc\fs18 1.29, 1.49 \cell -\pard\intbl\qc\fs18 1.29, 1.50 \cell +\pard\intbl\qc\fs18 (1.29, 1.49) \cell +\pard\intbl\qc\fs18 (1.31, 1.50) \cell +\pard\intbl\qc\fs18 (1.29, 1.50) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 3.4 \cell \pard\intbl\qc\fs18 3.7 \cell +\pard\intbl\qc\fs18 3.4 \cell \pard\intbl\qc\fs18 3.6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.36, 1.41 \cell -\pard\intbl\qc\fs18 1.35, 1.43 \cell -\pard\intbl\qc\fs18 1.35, 1.43 \cell +\pard\intbl\qc\fs18 (1.35, 1.43) \cell +\pard\intbl\qc\fs18 (1.36, 1.41) \cell +\pard\intbl\qc\fs18 (1.35, 1.43) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -699,10 +699,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 4h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 0-6h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -711,93 +711,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.73 (0.05) \cell -\pard\intbl\qc\fs18 1.74 (0.05) \cell -\pard\intbl\qc\fs18 1.74 (0.05) \cell +\pard\intbl\qc\fs18 26.7 (1.44) \cell +\pard\intbl\qc\fs18 26.8 (1.51) \cell +\pard\intbl\qc\fs18 26.8 (1.47) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.73 \cell -\pard\intbl\qc\fs18 1.74 \cell -\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 26.6 \cell +\pard\intbl\qc\fs18 26.8 \cell +\pard\intbl\qc\fs18 26.7 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.73 \cell -\pard\intbl\qc\fs18 1.74 \cell -\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 26.7 \cell +\pard\intbl\qc\fs18 26.8 \cell +\pard\intbl\qc\fs18 26.7 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.65, 1.84 \cell -\pard\intbl\qc\fs18 1.64, 1.83 \cell -\pard\intbl\qc\fs18 1.64, 1.84 \cell +\pard\intbl\qc\fs18 (24.5, 29.2) \cell +\pard\intbl\qc\fs18 (24.5, 29.2) \cell +\pard\intbl\qc\fs18 (24.5, 29.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 3.0 \cell -\pard\intbl\qc\fs18 3.2 \cell -\pard\intbl\qc\fs18 3.1 \cell +\pard\intbl\qc\fs18 5.4 \cell +\pard\intbl\qc\fs18 5.6 \cell +\pard\intbl\qc\fs18 5.5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.69, 1.78 \cell -\pard\intbl\qc\fs18 1.69, 1.79 \cell -\pard\intbl\qc\fs18 1.69, 1.78 \cell +\pard\intbl\qc\fs18 (25.6, 28.0) \cell +\pard\intbl\qc\fs18 (25.5, 28.3) \cell +\pard\intbl\qc\fs18 (25.5, 28.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -807,10 +807,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 0-6h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 4h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -819,93 +819,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 26.85 (1.51) \cell -\pard\intbl\qc\fs18 26.72 (1.44) \cell -\pard\intbl\qc\fs18 26.78 (1.47) \cell +\pard\intbl\qc\fs18 1.74 (0.0547) \cell +\pard\intbl\qc\fs18 1.73 (0.0521) \cell +\pard\intbl\qc\fs18 1.74 (0.0535) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 26.80 \cell -\pard\intbl\qc\fs18 26.63 \cell -\pard\intbl\qc\fs18 26.67 \cell +\pard\intbl\qc\fs18 1.74 \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 1.73 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 26.81 \cell -\pard\intbl\qc\fs18 26.68 \cell -\pard\intbl\qc\fs18 26.74 \cell +\pard\intbl\qc\fs18 1.74 \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 1.73 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 24.49, 29.19 \cell -\pard\intbl\qc\fs18 24.53, 29.25 \cell -\pard\intbl\qc\fs18 24.49, 29.25 \cell +\pard\intbl\qc\fs18 (1.64, 1.83) \cell +\pard\intbl\qc\fs18 (1.65, 1.84) \cell +\pard\intbl\qc\fs18 (1.64, 1.84) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 5.6 \cell -\pard\intbl\qc\fs18 5.4 \cell -\pard\intbl\qc\fs18 5.5 \cell +\pard\intbl\qc\fs18 3.2 \cell +\pard\intbl\qc\fs18 3.0 \cell +\pard\intbl\qc\fs18 3.1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 25.46, 28.28 \cell -\pard\intbl\qc\fs18 25.56, 28.01 \cell -\pard\intbl\qc\fs18 25.52, 28.17 \cell +\pard\intbl\qc\fs18 (1.69, 1.79) \cell +\pard\intbl\qc\fs18 (1.69, 1.78) \cell +\pard\intbl\qc\fs18 (1.69, 1.78) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -915,10 +915,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 6h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -927,33 +927,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.82 (0.05) \cell -\pard\intbl\qc\fs18 1.82 (0.05) \cell -\pard\intbl\qc\fs18 1.82 (0.05) \cell +\pard\intbl\qc\fs18 1.82 (0.0548) \cell +\pard\intbl\qc\fs18 1.82 (0.0538) \cell +\pard\intbl\qc\fs18 1.82 (0.0542) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell \pard\intbl\qc\fs18 1.82 \cell \pard\intbl\qc\fs18 1.82 \cell @@ -963,9 +963,9 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell \pard\intbl\qc\fs18 1.82 \cell \pard\intbl\qc\fs18 1.82 \cell @@ -975,21 +975,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.74, 1.92 \cell -\pard\intbl\qc\fs18 1.73, 1.91 \cell -\pard\intbl\qc\fs18 1.73, 1.92 \cell +\pard\intbl\qc\fs18 (1.73, 1.91) \cell +\pard\intbl\qc\fs18 (1.74, 1.92) \cell +\pard\intbl\qc\fs18 (1.73, 1.92) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell \pard\intbl\qc\fs18 3.0 \cell \pard\intbl\qc\fs18 3.0 \cell @@ -999,21 +999,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.77, 1.87 \cell -\pard\intbl\qc\fs18 1.77, 1.88 \cell -\pard\intbl\qc\fs18 1.77, 1.87 \cell +\pard\intbl\qc\fs18 (1.77, 1.88) \cell +\pard\intbl\qc\fs18 (1.77, 1.87) \cell +\pard\intbl\qc\fs18 (1.77, 1.87) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1023,10 +1023,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 8h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 8h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1035,33 +1035,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.84 (0.05) \cell -\pard\intbl\qc\fs18 1.84 (0.05) \cell -\pard\intbl\qc\fs18 1.84 (0.05) \cell +\pard\intbl\qc\fs18 1.84 (0.0548) \cell +\pard\intbl\qc\fs18 1.84 (0.0545) \cell +\pard\intbl\qc\fs18 1.84 (0.0545) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell \pard\intbl\qc\fs18 1.84 \cell \pard\intbl\qc\fs18 1.84 \cell @@ -1071,9 +1071,9 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell \pard\intbl\qc\fs18 1.84 \cell \pard\intbl\qc\fs18 1.84 \cell @@ -1083,21 +1083,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.76, 1.94 \cell -\pard\intbl\qc\fs18 1.75, 1.94 \cell -\pard\intbl\qc\fs18 1.75, 1.94 \cell +\pard\intbl\qc\fs18 (1.75, 1.94) \cell +\pard\intbl\qc\fs18 (1.76, 1.94) \cell +\pard\intbl\qc\fs18 (1.75, 1.94) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell \pard\intbl\qc\fs18 3.0 \cell \pard\intbl\qc\fs18 3.0 \cell @@ -1107,21 +1107,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.79, 1.90 \cell -\pard\intbl\qc\fs18 1.79, 1.90 \cell -\pard\intbl\qc\fs18 1.79, 1.90 \cell +\pard\intbl\qc\fs18 (1.79, 1.90) \cell +\pard\intbl\qc\fs18 (1.79, 1.90) \cell +\pard\intbl\qc\fs18 (1.79, 1.90) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1131,10 +1131,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6-12h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 6-12h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1143,93 +1143,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 22.67 (1.69) \cell -\pard\intbl\qc\fs18 22.52 (1.61) \cell -\pard\intbl\qc\fs18 22.58 (1.64) \cell +\pard\intbl\qc\fs18 22.5 (1.61) \cell +\pard\intbl\qc\fs18 22.7 (1.69) \cell +\pard\intbl\qc\fs18 22.6 (1.64) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 22.62 \cell -\pard\intbl\qc\fs18 22.43 \cell -\pard\intbl\qc\fs18 22.47 \cell +\pard\intbl\qc\fs18 22.4 \cell +\pard\intbl\qc\fs18 22.6 \cell +\pard\intbl\qc\fs18 22.5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 22.60 \cell -\pard\intbl\qc\fs18 22.47 \cell -\pard\intbl\qc\fs18 22.53 \cell +\pard\intbl\qc\fs18 22.5 \cell +\pard\intbl\qc\fs18 22.6 \cell +\pard\intbl\qc\fs18 22.5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 20.01, 25.27 \cell -\pard\intbl\qc\fs18 20.06, 25.34 \cell -\pard\intbl\qc\fs18 20.01, 25.34 \cell +\pard\intbl\qc\fs18 (20.1, 25.3) \cell +\pard\intbl\qc\fs18 (20.0, 25.3) \cell +\pard\intbl\qc\fs18 (20.0, 25.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 7.4 \cell \pard\intbl\qc\fs18 7.1 \cell +\pard\intbl\qc\fs18 7.4 \cell \pard\intbl\qc\fs18 7.3 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 21.11, 24.26 \cell -\pard\intbl\qc\fs18 21.23, 23.97 \cell -\pard\intbl\qc\fs18 21.18, 24.15 \cell +\pard\intbl\qc\fs18 (21.2, 24.0) \cell +\pard\intbl\qc\fs18 (21.1, 24.3) \cell +\pard\intbl\qc\fs18 (21.2, 24.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1239,10 +1239,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 12h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1251,93 +1251,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell +\pard\intbl\qc\fs18 0.549 (0.0297) \cell +\pard\intbl\qc\fs18 0.551 (0.0341) \cell +\pard\intbl\qc\fs18 0.550 (0.0316) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell +\pard\intbl\qc\fs18 0.548 \cell +\pard\intbl\qc\fs18 0.554 \cell +\pard\intbl\qc\fs18 0.550 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell +\pard\intbl\qc\fs18 0.548 \cell +\pard\intbl\qc\fs18 0.550 \cell +\pard\intbl\qc\fs18 0.549 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.49, 0.62 \cell -\pard\intbl\qc\fs18 0.49, 0.62 \cell -\pard\intbl\qc\fs18 0.49, 0.62 \cell +\pard\intbl\qc\fs18 (0.489, 0.620) \cell +\pard\intbl\qc\fs18 (0.486, 0.619) \cell +\pard\intbl\qc\fs18 (0.486, 0.620) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 6.2 \cell \pard\intbl\qc\fs18 5.4 \cell +\pard\intbl\qc\fs18 6.2 \cell \pard\intbl\qc\fs18 5.7 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.53, 0.58 \cell -\pard\intbl\qc\fs18 0.53, 0.57 \cell -\pard\intbl\qc\fs18 0.53, 0.57 \cell +\pard\intbl\qc\fs18 (0.529, 0.567) \cell +\pard\intbl\qc\fs18 (0.528, 0.577) \cell +\pard\intbl\qc\fs18 (0.529, 0.574) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1347,10 +1347,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 16h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 16h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1359,93 +1359,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.16 (0.02) \cell -\pard\intbl\qc\fs18 0.16 (0.02) \cell -\pard\intbl\qc\fs18 0.16 (0.02) \cell +\pard\intbl\qc\fs18 0.163 (0.0163) \cell +\pard\intbl\qc\fs18 0.165 (0.0181) \cell +\pard\intbl\qc\fs18 0.164 (0.0171) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.17 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.16 \cell +\pard\intbl\qc\fs18 0.161 \cell +\pard\intbl\qc\fs18 0.165 \cell +\pard\intbl\qc\fs18 0.163 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.16 \cell +\pard\intbl\qc\fs18 0.163 \cell +\pard\intbl\qc\fs18 0.164 \cell +\pard\intbl\qc\fs18 0.163 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.13, 0.20 \cell -\pard\intbl\qc\fs18 0.13, 0.20 \cell -\pard\intbl\qc\fs18 0.13, 0.20 \cell +\pard\intbl\qc\fs18 (0.135, 0.200) \cell +\pard\intbl\qc\fs18 (0.134, 0.198) \cell +\pard\intbl\qc\fs18 (0.134, 0.200) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 11.0 \cell \pard\intbl\qc\fs18 10.0 \cell +\pard\intbl\qc\fs18 11.0 \cell \pard\intbl\qc\fs18 10.4 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.15, 0.18 \cell -\pard\intbl\qc\fs18 0.15, 0.18 \cell -\pard\intbl\qc\fs18 0.15, 0.18 \cell +\pard\intbl\qc\fs18 (0.150, 0.177) \cell +\pard\intbl\qc\fs18 (0.148, 0.181) \cell +\pard\intbl\qc\fs18 (0.150, 0.178) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1455,10 +1455,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12-24h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 12-24h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1467,93 +1467,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 14.30 (2.04) \cell -\pard\intbl\qc\fs18 14.13 (1.95) \cell -\pard\intbl\qc\fs18 14.20 (1.99) \cell +\pard\intbl\qc\fs18 14.1 (1.95) \cell +\pard\intbl\qc\fs18 14.3 (2.04) \cell +\pard\intbl\qc\fs18 14.2 (1.99) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 14.26 \cell -\pard\intbl\qc\fs18 14.02 \cell -\pard\intbl\qc\fs18 14.07 \cell +\pard\intbl\qc\fs18 14.0 \cell +\pard\intbl\qc\fs18 14.3 \cell +\pard\intbl\qc\fs18 14.1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 14.15 \cell -\pard\intbl\qc\fs18 13.99 \cell -\pard\intbl\qc\fs18 14.06 \cell +\pard\intbl\qc\fs18 14.0 \cell +\pard\intbl\qc\fs18 14.2 \cell +\pard\intbl\qc\fs18 14.1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 11.07, 17.44 \cell -\pard\intbl\qc\fs18 11.13, 17.52 \cell -\pard\intbl\qc\fs18 11.07, 17.52 \cell +\pard\intbl\qc\fs18 (11.1, 17.5) \cell +\pard\intbl\qc\fs18 (11.1, 17.4) \cell +\pard\intbl\qc\fs18 (11.1, 17.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 14.3 \cell \pard\intbl\qc\fs18 13.8 \cell +\pard\intbl\qc\fs18 14.3 \cell \pard\intbl\qc\fs18 14.0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 12.41, 16.24 \cell -\pard\intbl\qc\fs18 12.56, 15.88 \cell -\pard\intbl\qc\fs18 12.50, 16.10 \cell +\pard\intbl\qc\fs18 (12.6, 15.9) \cell +\pard\intbl\qc\fs18 (12.4, 16.2) \cell +\pard\intbl\qc\fs18 (12.5, 16.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1563,10 +1563,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, Pre-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1575,93 +1575,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 94 \cell \pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 168 \cell +\pard\intbl\qc\fs18 166 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell +\pard\intbl\qc\fs18 0.0146 (0.00287) \cell +\pard\intbl\qc\fs18 0.0149 (0.00311) \cell +\pard\intbl\qc\fs18 0.0147 (0.00297) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell +\pard\intbl\qc\fs18 0.0142 \cell +\pard\intbl\qc\fs18 0.0146 \cell +\pard\intbl\qc\fs18 0.0143 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell +\pard\intbl\qc\fs18 0.0143 \cell +\pard\intbl\qc\fs18 0.0145 \cell +\pard\intbl\qc\fs18 0.0144 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell +\pard\intbl\qc\fs18 (0.0102, 0.0207) \cell +\pard\intbl\qc\fs18 (0.0100, 0.0203) \cell +\pard\intbl\qc\fs18 (0.0100, 0.0207) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 20.9 \cell \pard\intbl\qc\fs18 19.7 \cell +\pard\intbl\qc\fs18 20.9 \cell \pard\intbl\qc\fs18 20.2 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell +\pard\intbl\qc\fs18 (0.0122, 0.0168) \cell +\pard\intbl\qc\fs18 (0.0118, 0.0177) \cell +\pard\intbl\qc\fs18 (0.0121, 0.0174) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1671,10 +1671,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - Pre-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 24h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1683,93 +1683,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 96 \cell \pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 94 \cell -\pard\intbl\qc\fs18 166 \cell +\pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell +\pard\intbl\qc\fs18 0.0146 (0.00288) \cell +\pard\intbl\qc\fs18 0.0149 (0.00311) \cell +\pard\intbl\qc\fs18 0.0147 (0.00297) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell +\pard\intbl\qc\fs18 0.0142 \cell +\pard\intbl\qc\fs18 0.0146 \cell +\pard\intbl\qc\fs18 0.0143 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell +\pard\intbl\qc\fs18 0.0143 \cell +\pard\intbl\qc\fs18 0.0145 \cell +\pard\intbl\qc\fs18 0.0144 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell +\pard\intbl\qc\fs18 (0.0102, 0.0207) \cell +\pard\intbl\qc\fs18 (0.0100, 0.0203) \cell +\pard\intbl\qc\fs18 (0.0100, 0.0207) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 20.9 \cell \pard\intbl\qc\fs18 19.7 \cell +\pard\intbl\qc\fs18 20.9 \cell \pard\intbl\qc\fs18 20.2 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell +\pard\intbl\qc\fs18 (0.0123, 0.0170) \cell +\pard\intbl\qc\fs18 (0.0118, 0.0177) \cell +\pard\intbl\qc\fs18 (0.0122, 0.0174) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1779,10 +1779,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 36h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 36h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1791,69 +1791,69 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell \pard\intbl\qc\fs18 0.0 \cell \pard\intbl\qc\fs18 0.0 \cell @@ -1863,21 +1863,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1887,10 +1887,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24-48h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 24-48h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1899,93 +1899,93 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.28 (0.53) \cell -\pard\intbl\qc\fs18 0.22 (0.49) \cell -\pard\intbl\qc\fs18 0.25 (0.50) \cell +\pard\intbl\qc\fs18 0.224 (0.486) \cell +\pard\intbl\qc\fs18 0.278 (0.531) \cell +\pard\intbl\qc\fs18 0.247 (0.505) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.02 \cell +\pard\intbl\qc\fs18 0.0147 \cell +\pard\intbl\qc\fs18 0.0208 \cell +\pard\intbl\qc\fs18 0.0171 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 1.78 \cell -\pard\intbl\qc\fs18 0.00, 1.89 \cell -\pard\intbl\qc\fs18 0.00, 1.89 \cell +\pard\intbl\qc\fs18 (0.00500, 1.89) \cell +\pard\intbl\qc\fs18 (0.00500, 1.78) \cell +\pard\intbl\qc\fs18 (0.00500, 1.89) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 191.0 \cell \pard\intbl\qc\fs18 217.2 \cell +\pard\intbl\qc\fs18 191.0 \cell \pard\intbl\qc\fs18 204.4 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.18 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.182) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1995,10 +1995,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - 48h Post-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3, Pre-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2007,69 +2007,69 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 92 \cell \pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 168 \cell +\pard\intbl\qc\fs18 164 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell \pard\intbl\qc\fs18 0.0 \cell \pard\intbl\qc\fs18 0.0 \cell @@ -2079,21 +2079,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2103,10 +2103,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - Pre-dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3, 48h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2115,69 +2115,69 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 96 \cell \pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 92 \cell -\pard\intbl\qc\fs18 164 \cell +\pard\intbl\qc\fs18 168 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell \pard\intbl\qc\fs18 0.0 \cell \pard\intbl\qc\fs18 0.0 \cell @@ -2187,21 +2187,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2845 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4960 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7074 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2849 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4962 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7076 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2845 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4960 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7074 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2211,9 +2211,9 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4960 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7074 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tpk01b/tpk01part1of2.rtf b/tests/testthat/_snaps/tpk01b/tpk01part1of2.rtf new file mode 100644 index 00000000..5408c717 --- /dev/null +++ b/tests/testthat/_snaps/tpk01b/tpk01part1of2.rtf @@ -0,0 +1,576 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2832 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3433 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4806 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6179 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7552 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8925 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10298 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11328 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TPK01bpart1of2:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2832 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3433 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4806 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6179 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7552 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8925 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10298 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11328 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3433 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4806 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6179 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7552 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8925 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10298 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11328 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2832 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3433 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4806 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6179 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7552 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8925 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10298 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11328 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs18 \keepn\trhdr N \cell +\pard\intbl\qc\fs18 \keepn\trhdr Mean \cell +\pard\intbl\qc\fs18 \keepn\trhdr SD \cell +\pard\intbl\qc\fs18 \keepn\trhdr Med \cell +\pard\intbl\qc\fs18 \keepn\trhdr Min \cell +\pard\intbl\qc\fs18 \keepn\trhdr Max \cell +\pard\intbl\qc\fs18 \keepn\trhdr % CV \cell +\pard\intbl\qc\fs18 \keepn\trhdr Geometric Mean \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, Pre-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 NA \cell +\pard\intbl\qc\fs18 NA \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 5 Min Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0.100 \cell +\pard\intbl\qc\fs18 0.00571 \cell +\pard\intbl\qc\fs18 0.100 \cell +\pard\intbl\qc\fs18 0.0910 \cell +\pard\intbl\qc\fs18 0.111 \cell +\pard\intbl\qc\fs18 5.7 \cell +\pard\intbl\qc\fs18 0.0998 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 30 Min Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0.542 \cell +\pard\intbl\qc\fs18 0.0284 \cell +\pard\intbl\qc\fs18 0.543 \cell +\pard\intbl\qc\fs18 0.497 \cell +\pard\intbl\qc\fs18 0.596 \cell +\pard\intbl\qc\fs18 5.2 \cell +\pard\intbl\qc\fs18 0.541 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 1h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0.924 \cell +\pard\intbl\qc\fs18 0.0438 \cell +\pard\intbl\qc\fs18 0.921 \cell +\pard\intbl\qc\fs18 0.855 \cell +\pard\intbl\qc\fs18 1.01 \cell +\pard\intbl\qc\fs18 4.7 \cell +\pard\intbl\qc\fs18 0.923 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 1.5h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1.19 \cell +\pard\intbl\qc\fs18 0.0515 \cell +\pard\intbl\qc\fs18 1.19 \cell +\pard\intbl\qc\fs18 1.11 \cell +\pard\intbl\qc\fs18 1.29 \cell +\pard\intbl\qc\fs18 4.3 \cell +\pard\intbl\qc\fs18 1.19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 2h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1.38 \cell +\pard\intbl\qc\fs18 0.0549 \cell +\pard\intbl\qc\fs18 1.38 \cell +\pard\intbl\qc\fs18 1.30 \cell +\pard\intbl\qc\fs18 1.49 \cell +\pard\intbl\qc\fs18 4.0 \cell +\pard\intbl\qc\fs18 1.38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 0-6h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 26.8 \cell +\pard\intbl\qc\fs18 1.38 \cell +\pard\intbl\qc\fs18 26.7 \cell +\pard\intbl\qc\fs18 24.6 \cell +\pard\intbl\qc\fs18 29.2 \cell +\pard\intbl\qc\fs18 5.2 \cell +\pard\intbl\qc\fs18 26.8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 4h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 0.0543 \cell +\pard\intbl\qc\fs18 1.72 \cell +\pard\intbl\qc\fs18 1.65 \cell +\pard\intbl\qc\fs18 1.83 \cell +\pard\intbl\qc\fs18 3.1 \cell +\pard\intbl\qc\fs18 1.73 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 6h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 0.0516 \cell +\pard\intbl\qc\fs18 1.80 \cell +\pard\intbl\qc\fs18 1.74 \cell +\pard\intbl\qc\fs18 1.91 \cell +\pard\intbl\qc\fs18 2.8 \cell +\pard\intbl\qc\fs18 1.81 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 8h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1.83 \cell +\pard\intbl\qc\fs18 0.0504 \cell +\pard\intbl\qc\fs18 1.82 \cell +\pard\intbl\qc\fs18 1.76 \cell +\pard\intbl\qc\fs18 1.93 \cell +\pard\intbl\qc\fs18 2.8 \cell +\pard\intbl\qc\fs18 1.83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 6-12h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 22.6 \cell +\pard\intbl\qc\fs18 1.55 \cell +\pard\intbl\qc\fs18 22.5 \cell +\pard\intbl\qc\fs18 20.1 \cell +\pard\intbl\qc\fs18 25.3 \cell +\pard\intbl\qc\fs18 6.8 \cell +\pard\intbl\qc\fs18 22.6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 12h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0.548 \cell +\pard\intbl\qc\fs18 0.0221 \cell +\pard\intbl\qc\fs18 0.547 \cell +\pard\intbl\qc\fs18 0.499 \cell +\pard\intbl\qc\fs18 0.589 \cell +\pard\intbl\qc\fs18 4.0 \cell +\pard\intbl\qc\fs18 0.548 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 16h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0.164 \cell +\pard\intbl\qc\fs18 0.0137 \cell +\pard\intbl\qc\fs18 0.162 \cell +\pard\intbl\qc\fs18 0.137 \cell +\pard\intbl\qc\fs18 0.189 \cell +\pard\intbl\qc\fs18 8.4 \cell +\pard\intbl\qc\fs18 0.163 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 12-24h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 14.3 \cell +\pard\intbl\qc\fs18 1.87 \cell +\pard\intbl\qc\fs18 14.1 \cell +\pard\intbl\qc\fs18 11.2 \cell +\pard\intbl\qc\fs18 17.5 \cell +\pard\intbl\qc\fs18 13.1 \cell +\pard\intbl\qc\fs18 14.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, Pre-dose \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 0.0146 \cell +\pard\intbl\qc\fs18 0.00257 \cell +\pard\intbl\qc\fs18 0.0142 \cell +\pard\intbl\qc\fs18 0.0104 \cell +\pard\intbl\qc\fs18 0.0196 \cell +\pard\intbl\qc\fs18 17.6 \cell +\pard\intbl\qc\fs18 0.0144 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 24h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0.0147 \cell +\pard\intbl\qc\fs18 0.00260 \cell +\pard\intbl\qc\fs18 0.0142 \cell +\pard\intbl\qc\fs18 0.0104 \cell +\pard\intbl\qc\fs18 0.0196 \cell +\pard\intbl\qc\fs18 17.7 \cell +\pard\intbl\qc\fs18 0.0145 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 36h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 24-48h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0.218 \cell +\pard\intbl\qc\fs18 0.483 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 1.89 \cell +\pard\intbl\qc\fs18 221.5 \cell +\pard\intbl\qc\fs18 0.0142 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3, Pre-dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3433 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4806 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6179 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7552 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8925 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10298 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11328 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3, 48h Post-dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2832 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3433 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4806 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6179 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7552 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8925 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10298 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11328 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3433 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4806 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7552 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8925 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10298 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11328 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tpk01bpart1/tpk01bpart1of2.rtf b/tests/testthat/_snaps/tpk01bpart1/tpk01bpart1of2.rtf deleted file mode 100755 index 9e70ac89..00000000 --- a/tests/testthat/_snaps/tpk01bpart1/tpk01bpart1of2.rtf +++ /dev/null @@ -1,598 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2850 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3746 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6188 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7491 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8793 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10096 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11399 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TPK01bpart1of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2850 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3746 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6188 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7491 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8793 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10096 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11399 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3746 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5048 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6188 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7491 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8793 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10096 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11399 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3746 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6188 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7491 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8793 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10096 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11399 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2850 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3746 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5048 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6188 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7491 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8793 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10096 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11399 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell -\pard\intbl\qc\fs18 \keepn\trhdr N \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean \cell -\pard\intbl\qc\fs18 \keepn\trhdr SD \cell -\pard\intbl\qc\fs18 \keepn\trhdr Med \cell -\pard\intbl\qc\fs18 \keepn\trhdr Min \cell -\pard\intbl\qc\fs18 \keepn\trhdr Max \cell -\pard\intbl\qc\fs18 \keepn\trhdr % CV \cell -\pard\intbl\qc\fs18 \keepn\trhdr Geometric Mean \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - Pre-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 5 Min Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.09 \cell -\pard\intbl\qc\fs18 0.11 \cell -\pard\intbl\qc\fs18 4.9 \cell -\pard\intbl\qc\fs18 0.10 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 30 Min Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.50 \cell -\pard\intbl\qc\fs18 0.60 \cell -\pard\intbl\qc\fs18 4.4 \cell -\pard\intbl\qc\fs18 0.54 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.04 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.86 \cell -\pard\intbl\qc\fs18 1.02 \cell -\pard\intbl\qc\fs18 4.0 \cell -\pard\intbl\qc\fs18 0.93 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1.5h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 1.20 \cell -\pard\intbl\qc\fs18 0.04 \cell -\pard\intbl\qc\fs18 1.20 \cell -\pard\intbl\qc\fs18 1.12 \cell -\pard\intbl\qc\fs18 1.31 \cell -\pard\intbl\qc\fs18 3.7 \cell -\pard\intbl\qc\fs18 1.20 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 2h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 1.39 \cell -\pard\intbl\qc\fs18 0.05 \cell -\pard\intbl\qc\fs18 1.38 \cell -\pard\intbl\qc\fs18 1.31 \cell -\pard\intbl\qc\fs18 1.50 \cell -\pard\intbl\qc\fs18 3.4 \cell -\pard\intbl\qc\fs18 1.39 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 4h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 1.73 \cell -\pard\intbl\qc\fs18 0.05 \cell -\pard\intbl\qc\fs18 1.73 \cell -\pard\intbl\qc\fs18 1.65 \cell -\pard\intbl\qc\fs18 1.84 \cell -\pard\intbl\qc\fs18 3.0 \cell -\pard\intbl\qc\fs18 1.73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 0-6h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 26.85 \cell -\pard\intbl\qc\fs18 1.51 \cell -\pard\intbl\qc\fs18 26.80 \cell -\pard\intbl\qc\fs18 24.49 \cell -\pard\intbl\qc\fs18 29.19 \cell -\pard\intbl\qc\fs18 5.6 \cell -\pard\intbl\qc\fs18 26.81 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 1.82 \cell -\pard\intbl\qc\fs18 0.05 \cell -\pard\intbl\qc\fs18 1.82 \cell -\pard\intbl\qc\fs18 1.74 \cell -\pard\intbl\qc\fs18 1.92 \cell -\pard\intbl\qc\fs18 3.0 \cell -\pard\intbl\qc\fs18 1.82 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 8h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 1.84 \cell -\pard\intbl\qc\fs18 0.05 \cell -\pard\intbl\qc\fs18 1.84 \cell -\pard\intbl\qc\fs18 1.76 \cell -\pard\intbl\qc\fs18 1.94 \cell -\pard\intbl\qc\fs18 3.0 \cell -\pard\intbl\qc\fs18 1.84 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6-12h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 22.67 \cell -\pard\intbl\qc\fs18 1.69 \cell -\pard\intbl\qc\fs18 22.62 \cell -\pard\intbl\qc\fs18 20.01 \cell -\pard\intbl\qc\fs18 25.27 \cell -\pard\intbl\qc\fs18 7.4 \cell -\pard\intbl\qc\fs18 22.60 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.03 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.49 \cell -\pard\intbl\qc\fs18 0.62 \cell -\pard\intbl\qc\fs18 6.2 \cell -\pard\intbl\qc\fs18 0.55 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 16h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 0.17 \cell -\pard\intbl\qc\fs18 0.13 \cell -\pard\intbl\qc\fs18 0.20 \cell -\pard\intbl\qc\fs18 11.0 \cell -\pard\intbl\qc\fs18 0.16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12-24h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 14.30 \cell -\pard\intbl\qc\fs18 2.04 \cell -\pard\intbl\qc\fs18 14.26 \cell -\pard\intbl\qc\fs18 11.07 \cell -\pard\intbl\qc\fs18 17.44 \cell -\pard\intbl\qc\fs18 14.3 \cell -\pard\intbl\qc\fs18 14.15 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 20.9 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - Pre-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 20.9 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 36h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24-48h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.28 \cell -\pard\intbl\qc\fs18 0.53 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 1.78 \cell -\pard\intbl\qc\fs18 191.0 \cell -\pard\intbl\qc\fs18 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - 48h Post-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - Pre-dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2850 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3746 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5048 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6188 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7491 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8793 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10096 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11399 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tpk01bpart2/tpk01bpart2of2.rtf b/tests/testthat/_snaps/tpk01bpart2/tpk01bpart2of2.rtf deleted file mode 100755 index 8a914a22..00000000 --- a/tests/testthat/_snaps/tpk01bpart2/tpk01bpart2of2.rtf +++ /dev/null @@ -1,598 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2850 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3746 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6188 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7491 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8793 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10096 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11399 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TPK01bpart2of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2850 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3746 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6188 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7491 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8793 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10096 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11399 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3746 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5048 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6188 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7491 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8793 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10096 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11399 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3746 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6188 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7491 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8793 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10096 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11399 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\pard\intbl\qc\fs18 \keepn\trhdr Observed \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2850 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3746 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5048 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6188 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7491 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8793 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10096 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11399 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell -\pard\intbl\qc\fs18 \keepn\trhdr N \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean \cell -\pard\intbl\qc\fs18 \keepn\trhdr SD \cell -\pard\intbl\qc\fs18 \keepn\trhdr Med \cell -\pard\intbl\qc\fs18 \keepn\trhdr Min \cell -\pard\intbl\qc\fs18 \keepn\trhdr Max \cell -\pard\intbl\qc\fs18 \keepn\trhdr % CV \cell -\pard\intbl\qc\fs18 \keepn\trhdr Geometric Mean \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - Pre-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 5 Min Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.09 \cell -\pard\intbl\qc\fs18 0.11 \cell -\pard\intbl\qc\fs18 5.3 \cell -\pard\intbl\qc\fs18 0.10 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 30 Min Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.03 \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.50 \cell -\pard\intbl\qc\fs18 0.60 \cell -\pard\intbl\qc\fs18 4.8 \cell -\pard\intbl\qc\fs18 0.55 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.04 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.85 \cell -\pard\intbl\qc\fs18 1.01 \cell -\pard\intbl\qc\fs18 4.4 \cell -\pard\intbl\qc\fs18 0.93 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1.5h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 1.20 \cell -\pard\intbl\qc\fs18 0.05 \cell -\pard\intbl\qc\fs18 1.20 \cell -\pard\intbl\qc\fs18 1.11 \cell -\pard\intbl\qc\fs18 1.29 \cell -\pard\intbl\qc\fs18 4.0 \cell -\pard\intbl\qc\fs18 1.20 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 2h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 1.39 \cell -\pard\intbl\qc\fs18 0.05 \cell -\pard\intbl\qc\fs18 1.39 \cell -\pard\intbl\qc\fs18 1.29 \cell -\pard\intbl\qc\fs18 1.49 \cell -\pard\intbl\qc\fs18 3.7 \cell -\pard\intbl\qc\fs18 1.39 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 4h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 1.74 \cell -\pard\intbl\qc\fs18 0.05 \cell -\pard\intbl\qc\fs18 1.74 \cell -\pard\intbl\qc\fs18 1.64 \cell -\pard\intbl\qc\fs18 1.83 \cell -\pard\intbl\qc\fs18 3.2 \cell -\pard\intbl\qc\fs18 1.74 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 0-6h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 26.72 \cell -\pard\intbl\qc\fs18 1.44 \cell -\pard\intbl\qc\fs18 26.63 \cell -\pard\intbl\qc\fs18 24.53 \cell -\pard\intbl\qc\fs18 29.25 \cell -\pard\intbl\qc\fs18 5.4 \cell -\pard\intbl\qc\fs18 26.68 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 1.82 \cell -\pard\intbl\qc\fs18 0.05 \cell -\pard\intbl\qc\fs18 1.82 \cell -\pard\intbl\qc\fs18 1.73 \cell -\pard\intbl\qc\fs18 1.91 \cell -\pard\intbl\qc\fs18 3.0 \cell -\pard\intbl\qc\fs18 1.82 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 8h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 1.84 \cell -\pard\intbl\qc\fs18 0.05 \cell -\pard\intbl\qc\fs18 1.84 \cell -\pard\intbl\qc\fs18 1.75 \cell -\pard\intbl\qc\fs18 1.94 \cell -\pard\intbl\qc\fs18 3.0 \cell -\pard\intbl\qc\fs18 1.84 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6-12h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 22.52 \cell -\pard\intbl\qc\fs18 1.61 \cell -\pard\intbl\qc\fs18 22.43 \cell -\pard\intbl\qc\fs18 20.06 \cell -\pard\intbl\qc\fs18 25.34 \cell -\pard\intbl\qc\fs18 7.1 \cell -\pard\intbl\qc\fs18 22.47 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.03 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.49 \cell -\pard\intbl\qc\fs18 0.62 \cell -\pard\intbl\qc\fs18 5.4 \cell -\pard\intbl\qc\fs18 0.55 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 16h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.13 \cell -\pard\intbl\qc\fs18 0.20 \cell -\pard\intbl\qc\fs18 10.0 \cell -\pard\intbl\qc\fs18 0.16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12-24h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 14.13 \cell -\pard\intbl\qc\fs18 1.95 \cell -\pard\intbl\qc\fs18 14.02 \cell -\pard\intbl\qc\fs18 11.13 \cell -\pard\intbl\qc\fs18 17.52 \cell -\pard\intbl\qc\fs18 13.8 \cell -\pard\intbl\qc\fs18 13.99 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 19.7 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - Pre-dose \cell -\pard\intbl\qc\fs18 94 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 19.7 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 36h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24-48h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 0.22 \cell -\pard\intbl\qc\fs18 0.49 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 1.89 \cell -\pard\intbl\qc\fs18 217.2 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - 48h Post-dose \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2850 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3746 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5048 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6188 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7491 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8793 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10096 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11399 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - Pre-dose \cell -\pard\intbl\qc\fs18 92 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2850 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3746 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5048 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6188 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7491 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8793 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10096 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11399 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2850 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3746 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5048 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6188 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7491 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8793 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10096 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11399 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tpk02/tpk02part1of2.rtf b/tests/testthat/_snaps/tpk02/tpk02part1of2.rtf new file mode 100644 index 00000000..c31018c4 --- /dev/null +++ b/tests/testthat/_snaps/tpk02/tpk02part1of2.rtf @@ -0,0 +1,2608 @@ +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4489 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6021 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7658 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TPK02part1of2:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2852 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4489 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6021 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7658 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4489 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6021 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7658 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4489 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6021 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7658 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Body Weight (kg) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Body Weight (kg) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Body Weight (kg) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Body Weight (kg) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4489 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6021 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7658 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs18 \keepn\trhdr <30 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805?30 to <60 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805?60 to <90 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805?90 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, Pre-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 NA \cell +\pard\intbl\qc\fs18 NA \cell +\pard\intbl\qc\fs18 NA \cell +\pard\intbl\qc\fs18 NA \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 NA \cell +\pard\intbl\qc\fs18 NA \cell +\pard\intbl\qc\fs18 NA \cell +\pard\intbl\qc\fs18 NA \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 5 Min Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.0993 (0.00637) \cell +\pard\intbl\qc\fs18 0.101 (0.00561) \cell +\pard\intbl\qc\fs18 0.0982 (0.00321) \cell +\pard\intbl\qc\fs18 0.100 (0.00621) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.0994 \cell +\pard\intbl\qc\fs18 0.103 \cell +\pard\intbl\qc\fs18 0.0996 \cell +\pard\intbl\qc\fs18 0.0988 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.0992 \cell +\pard\intbl\qc\fs18 0.101 \cell +\pard\intbl\qc\fs18 0.0981 \cell +\pard\intbl\qc\fs18 0.100 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.0919, 0.111) \cell +\pard\intbl\qc\fs18 (0.0921, 0.109) \cell +\pard\intbl\qc\fs18 (0.0928, 0.101) \cell +\pard\intbl\qc\fs18 (0.0910, 0.110) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 6.4 \cell +\pard\intbl\qc\fs18 5.6 \cell +\pard\intbl\qc\fs18 3.3 \cell +\pard\intbl\qc\fs18 6.2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.0921, 0.104) \cell +\pard\intbl\qc\fs18 (0.0964, 0.105) \cell +\pard\intbl\qc\fs18 (0.0958, 0.101) \cell +\pard\intbl\qc\fs18 (0.0951, 0.106) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 30 Min Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.539 (0.0316) \cell +\pard\intbl\qc\fs18 0.548 (0.0280) \cell +\pard\intbl\qc\fs18 0.533 (0.0153) \cell +\pard\intbl\qc\fs18 0.544 (0.0309) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.540 \cell +\pard\intbl\qc\fs18 0.556 \cell +\pard\intbl\qc\fs18 0.540 \cell +\pard\intbl\qc\fs18 0.537 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.538 \cell +\pard\intbl\qc\fs18 0.547 \cell +\pard\intbl\qc\fs18 0.533 \cell +\pard\intbl\qc\fs18 0.543 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.503, 0.596) \cell +\pard\intbl\qc\fs18 (0.503, 0.587) \cell +\pard\intbl\qc\fs18 (0.507, 0.544) \cell +\pard\intbl\qc\fs18 (0.497, 0.593) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 5.9 \cell +\pard\intbl\qc\fs18 5.1 \cell +\pard\intbl\qc\fs18 2.9 \cell +\pard\intbl\qc\fs18 5.7 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.504, 0.563) \cell +\pard\intbl\qc\fs18 (0.525, 0.570) \cell +\pard\intbl\qc\fs18 (0.521, 0.544) \cell +\pard\intbl\qc\fs18 (0.519, 0.573) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 1h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.920 (0.0486) \cell +\pard\intbl\qc\fs18 0.933 (0.0435) \cell +\pard\intbl\qc\fs18 0.909 (0.0225) \cell +\pard\intbl\qc\fs18 0.927 (0.0476) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.921 \cell +\pard\intbl\qc\fs18 0.946 \cell +\pard\intbl\qc\fs18 0.921 \cell +\pard\intbl\qc\fs18 0.917 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.919 \cell +\pard\intbl\qc\fs18 0.932 \cell +\pard\intbl\qc\fs18 0.909 \cell +\pard\intbl\qc\fs18 0.926 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.864, 1.01) \cell +\pard\intbl\qc\fs18 (0.864, 0.995) \cell +\pard\intbl\qc\fs18 (0.871, 0.926) \cell +\pard\intbl\qc\fs18 (0.855, 1.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 5.3 \cell +\pard\intbl\qc\fs18 4.7 \cell +\pard\intbl\qc\fs18 2.5 \cell +\pard\intbl\qc\fs18 5.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.867, 0.958) \cell +\pard\intbl\qc\fs18 (0.900, 0.968) \cell +\pard\intbl\qc\fs18 (0.891, 0.923) \cell +\pard\intbl\qc\fs18 (0.890, 0.974) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 1.5h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.19 (0.0569) \cell +\pard\intbl\qc\fs18 1.20 (0.0516) \cell +\pard\intbl\qc\fs18 1.18 (0.0255) \cell +\pard\intbl\qc\fs18 1.20 (0.0561) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 1.19 \cell +\pard\intbl\qc\fs18 1.22 \cell +\pard\intbl\qc\fs18 1.19 \cell +\pard\intbl\qc\fs18 1.19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 1.19 \cell +\pard\intbl\qc\fs18 1.20 \cell +\pard\intbl\qc\fs18 1.17 \cell +\pard\intbl\qc\fs18 1.20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.12, 1.29) \cell +\pard\intbl\qc\fs18 (1.12, 1.28) \cell +\pard\intbl\qc\fs18 (1.13, 1.20) \cell +\pard\intbl\qc\fs18 (1.11, 1.28) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 4.8 \cell +\pard\intbl\qc\fs18 4.3 \cell +\pard\intbl\qc\fs18 2.2 \cell +\pard\intbl\qc\fs18 4.7 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.13, 1.24) \cell +\pard\intbl\qc\fs18 (1.16, 1.25) \cell +\pard\intbl\qc\fs18 (1.15, 1.20) \cell +\pard\intbl\qc\fs18 (1.15, 1.25) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 2h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.38 (0.0602) \cell +\pard\intbl\qc\fs18 1.39 (0.0553) \cell +\pard\intbl\qc\fs18 1.36 (0.0266) \cell +\pard\intbl\qc\fs18 1.39 (0.0599) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 1.38 \cell +\pard\intbl\qc\fs18 1.40 \cell +\pard\intbl\qc\fs18 1.37 \cell +\pard\intbl\qc\fs18 1.38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 1.38 \cell +\pard\intbl\qc\fs18 1.39 \cell +\pard\intbl\qc\fs18 1.36 \cell +\pard\intbl\qc\fs18 1.39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.31, 1.49) \cell +\pard\intbl\qc\fs18 (1.31, 1.48) \cell +\pard\intbl\qc\fs18 (1.32, 1.39) \cell +\pard\intbl\qc\fs18 (1.30, 1.48) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 4.4 \cell +\pard\intbl\qc\fs18 4.0 \cell +\pard\intbl\qc\fs18 2.0 \cell +\pard\intbl\qc\fs18 4.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.32, 1.43) \cell +\pard\intbl\qc\fs18 (1.35, 1.44) \cell +\pard\intbl\qc\fs18 (1.34, 1.38) \cell +\pard\intbl\qc\fs18 (1.34, 1.45) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 0-6h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 27.1 (1.49) \cell +\pard\intbl\qc\fs18 26.5 (1.27) \cell +\pard\intbl\qc\fs18 27.0 (1.28) \cell +\pard\intbl\qc\fs18 26.8 (1.48) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 26.6 \cell +\pard\intbl\qc\fs18 26.3 \cell +\pard\intbl\qc\fs18 26.9 \cell +\pard\intbl\qc\fs18 26.8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 27.0 \cell +\pard\intbl\qc\fs18 26.5 \cell +\pard\intbl\qc\fs18 26.9 \cell +\pard\intbl\qc\fs18 26.8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (24.8, 29.2) \cell +\pard\intbl\qc\fs18 (24.6, 28.6) \cell +\pard\intbl\qc\fs18 (25.6, 28.6) \cell +\pard\intbl\qc\fs18 (24.6, 28.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 5.5 \cell +\pard\intbl\qc\fs18 4.8 \cell +\pard\intbl\qc\fs18 4.7 \cell +\pard\intbl\qc\fs18 5.5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (25.8, 28.6) \cell +\pard\intbl\qc\fs18 (25.7, 27.8) \cell +\pard\intbl\qc\fs18 (25.7, 28.0) \cell +\pard\intbl\qc\fs18 (25.6, 28.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 4h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.72 (0.0567) \cell +\pard\intbl\qc\fs18 1.74 (0.0559) \cell +\pard\intbl\qc\fs18 1.70 (0.0290) \cell +\pard\intbl\qc\fs18 1.73 (0.0597) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 1.69 \cell +\pard\intbl\qc\fs18 1.72 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 1.72 \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 1.70 \cell +\pard\intbl\qc\fs18 1.73 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.66, 1.83) \cell +\pard\intbl\qc\fs18 (1.66, 1.82) \cell +\pard\intbl\qc\fs18 (1.67, 1.75) \cell +\pard\intbl\qc\fs18 (1.65, 1.82) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 3.3 \cell +\pard\intbl\qc\fs18 3.2 \cell +\pard\intbl\qc\fs18 1.7 \cell +\pard\intbl\qc\fs18 3.4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.67, 1.78) \cell +\pard\intbl\qc\fs18 (1.68, 1.78) \cell +\pard\intbl\qc\fs18 (1.68, 1.72) \cell +\pard\intbl\qc\fs18 (1.68, 1.79) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 6h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.81 (0.0516) \cell +\pard\intbl\qc\fs18 1.82 (0.0535) \cell +\pard\intbl\qc\fs18 1.79 (0.0315) \cell +\pard\intbl\qc\fs18 1.82 (0.0570) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 1.77 \cell +\pard\intbl\qc\fs18 1.81 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 1.82 \cell +\pard\intbl\qc\fs18 1.79 \cell +\pard\intbl\qc\fs18 1.82 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.75, 1.91) \cell +\pard\intbl\qc\fs18 (1.75, 1.90) \cell +\pard\intbl\qc\fs18 (1.77, 1.85) \cell +\pard\intbl\qc\fs18 (1.74, 1.90) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 2.9 \cell +\pard\intbl\qc\fs18 2.9 \cell +\pard\intbl\qc\fs18 1.8 \cell +\pard\intbl\qc\fs18 3.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.77, 1.87) \cell +\pard\intbl\qc\fs18 (1.77, 1.86) \cell +\pard\intbl\qc\fs18 (1.77, 1.80) \cell +\pard\intbl\qc\fs18 (1.77, 1.88) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 8h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.83 (0.0494) \cell +\pard\intbl\qc\fs18 1.84 (0.0524) \cell +\pard\intbl\qc\fs18 1.81 (0.0327) \cell +\pard\intbl\qc\fs18 1.84 (0.0558) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 1.84 \cell +\pard\intbl\qc\fs18 1.83 \cell +\pard\intbl\qc\fs18 1.79 \cell +\pard\intbl\qc\fs18 1.84 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 1.83 \cell +\pard\intbl\qc\fs18 1.84 \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 1.84 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.77, 1.93) \cell +\pard\intbl\qc\fs18 (1.77, 1.92) \cell +\pard\intbl\qc\fs18 (1.78, 1.87) \cell +\pard\intbl\qc\fs18 (1.76, 1.91) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 2.7 \cell +\pard\intbl\qc\fs18 2.8 \cell +\pard\intbl\qc\fs18 1.8 \cell +\pard\intbl\qc\fs18 3.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.80, 1.88) \cell +\pard\intbl\qc\fs18 (1.79, 1.88) \cell +\pard\intbl\qc\fs18 (1.79, 1.82) \cell +\pard\intbl\qc\fs18 (1.80, 1.90) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 6-12h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 22.9 (1.66) \cell +\pard\intbl\qc\fs18 22.3 (1.43) \cell +\pard\intbl\qc\fs18 22.8 (1.43) \cell +\pard\intbl\qc\fs18 22.6 (1.66) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 22.4 \cell +\pard\intbl\qc\fs18 22.0 \cell +\pard\intbl\qc\fs18 22.8 \cell +\pard\intbl\qc\fs18 22.7 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 22.8 \cell +\pard\intbl\qc\fs18 22.2 \cell +\pard\intbl\qc\fs18 22.8 \cell +\pard\intbl\qc\fs18 22.6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (20.4, 25.3) \cell +\pard\intbl\qc\fs18 (20.1, 24.6) \cell +\pard\intbl\qc\fs18 (21.2, 24.7) \cell +\pard\intbl\qc\fs18 (20.1, 24.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 7.3 \cell +\pard\intbl\qc\fs18 6.4 \cell +\pard\intbl\qc\fs18 6.3 \cell +\pard\intbl\qc\fs18 7.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (21.5, 24.6) \cell +\pard\intbl\qc\fs18 (21.4, 23.7) \cell +\pard\intbl\qc\fs18 (21.3, 23.9) \cell +\pard\intbl\qc\fs18 (21.3, 24.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 12h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.552 (0.0182) \cell +\pard\intbl\qc\fs18 0.544 (0.0197) \cell +\pard\intbl\qc\fs18 0.544 (0.0289) \cell +\pard\intbl\qc\fs18 0.550 (0.0243) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.550 \cell +\pard\intbl\qc\fs18 0.545 \cell +\pard\intbl\qc\fs18 0.544 \cell +\pard\intbl\qc\fs18 0.548 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.552 \cell +\pard\intbl\qc\fs18 0.544 \cell +\pard\intbl\qc\fs18 0.543 \cell +\pard\intbl\qc\fs18 0.549 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.531, 0.584) \cell +\pard\intbl\qc\fs18 (0.499, 0.565) \cell +\pard\intbl\qc\fs18 (0.510, 0.582) \cell +\pard\intbl\qc\fs18 (0.510, 0.589) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 3.3 \cell +\pard\intbl\qc\fs18 3.6 \cell +\pard\intbl\qc\fs18 5.3 \cell +\pard\intbl\qc\fs18 4.4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.536, 0.564) \cell +\pard\intbl\qc\fs18 (0.534, 0.561) \cell +\pard\intbl\qc\fs18 (0.515, 0.570) \cell +\pard\intbl\qc\fs18 (0.532, 0.567) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 16h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.166 (0.0136) \cell +\pard\intbl\qc\fs18 0.161 (0.0121) \cell +\pard\intbl\qc\fs18 0.163 (0.0156) \cell +\pard\intbl\qc\fs18 0.164 (0.0149) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.164 \cell +\pard\intbl\qc\fs18 0.158 \cell +\pard\intbl\qc\fs18 0.163 \cell +\pard\intbl\qc\fs18 0.161 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.166 \cell +\pard\intbl\qc\fs18 0.160 \cell +\pard\intbl\qc\fs18 0.163 \cell +\pard\intbl\qc\fs18 0.163 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.149, 0.189) \cell +\pard\intbl\qc\fs18 (0.137, 0.178) \cell +\pard\intbl\qc\fs18 (0.145, 0.180) \cell +\pard\intbl\qc\fs18 (0.141, 0.187) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 8.2 \cell +\pard\intbl\qc\fs18 7.5 \cell +\pard\intbl\qc\fs18 9.5 \cell +\pard\intbl\qc\fs18 9.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.153, 0.178) \cell +\pard\intbl\qc\fs18 (0.154, 0.171) \cell +\pard\intbl\qc\fs18 (0.147, 0.180) \cell +\pard\intbl\qc\fs18 (0.152, 0.179) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 12-24h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 14.6 (2.01) \cell +\pard\intbl\qc\fs18 13.8 (1.73) \cell +\pard\intbl\qc\fs18 14.5 (1.73) \cell +\pard\intbl\qc\fs18 14.3 (2.02) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 14.0 \cell +\pard\intbl\qc\fs18 13.5 \cell +\pard\intbl\qc\fs18 14.5 \cell +\pard\intbl\qc\fs18 14.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 14.5 \cell +\pard\intbl\qc\fs18 13.7 \cell +\pard\intbl\qc\fs18 14.4 \cell +\pard\intbl\qc\fs18 14.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (11.6, 17.5) \cell +\pard\intbl\qc\fs18 (11.2, 16.6) \cell +\pard\intbl\qc\fs18 (12.5, 16.7) \cell +\pard\intbl\qc\fs18 (11.2, 17.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 13.8 \cell +\pard\intbl\qc\fs18 12.5 \cell +\pard\intbl\qc\fs18 12.0 \cell +\pard\intbl\qc\fs18 14.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (12.9, 16.7) \cell +\pard\intbl\qc\fs18 (12.8, 15.6) \cell +\pard\intbl\qc\fs18 (12.7, 15.8) \cell +\pard\intbl\qc\fs18 (12.6, 16.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, Pre-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 16 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.0151 (0.00278) \cell +\pard\intbl\qc\fs18 0.0141 (0.00228) \cell +\pard\intbl\qc\fs18 0.0148 (0.00267) \cell +\pard\intbl\qc\fs18 0.0145 (0.00273) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.0142 \cell +\pard\intbl\qc\fs18 0.0135 \cell +\pard\intbl\qc\fs18 0.0146 \cell +\pard\intbl\qc\fs18 0.0143 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.0149 \cell +\pard\intbl\qc\fs18 0.0139 \cell +\pard\intbl\qc\fs18 0.0146 \cell +\pard\intbl\qc\fs18 0.0143 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.0114, 0.0196) \cell +\pard\intbl\qc\fs18 (0.0104, 0.0178) \cell +\pard\intbl\qc\fs18 (0.0118, 0.0181) \cell +\pard\intbl\qc\fs18 (0.0107, 0.0183) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 18.4 \cell +\pard\intbl\qc\fs18 16.2 \cell +\pard\intbl\qc\fs18 18.1 \cell +\pard\intbl\qc\fs18 18.8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.0126, 0.0178) \cell +\pard\intbl\qc\fs18 (0.0127, 0.0162) \cell +\pard\intbl\qc\fs18 (0.0121, 0.0173) \cell +\pard\intbl\qc\fs18 (0.0124, 0.0173) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 24h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.0151 (0.00278) \cell +\pard\intbl\qc\fs18 0.0141 (0.00228) \cell +\pard\intbl\qc\fs18 0.0148 (0.00267) \cell +\pard\intbl\qc\fs18 0.0147 (0.00278) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.0142 \cell +\pard\intbl\qc\fs18 0.0135 \cell +\pard\intbl\qc\fs18 0.0146 \cell +\pard\intbl\qc\fs18 0.0143 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.0149 \cell +\pard\intbl\qc\fs18 0.0139 \cell +\pard\intbl\qc\fs18 0.0146 \cell +\pard\intbl\qc\fs18 0.0145 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.0114, 0.0196) \cell +\pard\intbl\qc\fs18 (0.0104, 0.0178) \cell +\pard\intbl\qc\fs18 (0.0118, 0.0181) \cell +\pard\intbl\qc\fs18 (0.0107, 0.0190) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 18.4 \cell +\pard\intbl\qc\fs18 16.2 \cell +\pard\intbl\qc\fs18 18.1 \cell +\pard\intbl\qc\fs18 18.9 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.0126, 0.0178) \cell +\pard\intbl\qc\fs18 (0.0127, 0.0162) \cell +\pard\intbl\qc\fs18 (0.0121, 0.0173) \cell +\pard\intbl\qc\fs18 (0.0128, 0.0174) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 36h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 24-48h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.400 (0.728) \cell +\pard\intbl\qc\fs18 0.0767 (0.227) \cell +\pard\intbl\qc\fs18 0.144 (0.341) \cell +\pard\intbl\qc\fs18 0.210 (0.441) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.0230 \cell +\pard\intbl\qc\fs18 0.00822 \cell +\pard\intbl\qc\fs18 0.0117 \cell +\pard\intbl\qc\fs18 0.0153 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 1.89) \cell +\pard\intbl\qc\fs18 (0.00500, 0.722) \cell +\pard\intbl\qc\fs18 (0.00500, 0.840) \cell +\pard\intbl\qc\fs18 (0.00500, 1.24) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 182.1 \cell +\pard\intbl\qc\fs18 295.6 \cell +\pard\intbl\qc\fs18 236.5 \cell +\pard\intbl\qc\fs18 210.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.763) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3, Pre-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 16 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3, 48h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4489 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6021 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7658 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4489 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6021 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7658 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4489 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6021 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7658 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tpk02part1/tpk02part1of2.rtf b/tests/testthat/_snaps/tpk02part1/tpk02part1of2.rtf deleted file mode 100644 index bd596373..00000000 --- a/tests/testthat/_snaps/tpk02part1/tpk02part1of2.rtf +++ /dev/null @@ -1,2608 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2881 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7612 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TPK02part1of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2881 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7612 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7612 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7612 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr [Body Weight (kg)] [Quartiles] \cell -\pard\intbl\qc\fs18 \keepn\trhdr [Body Weight (kg)] [Quartiles] \cell -\pard\intbl\qc\fs18 \keepn\trhdr [Body Weight (kg)] [Quartiles] \cell -\pard\intbl\qc\fs18 \keepn\trhdr [Body Weight (kg)] [Quartiles] \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2881 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4458 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6035 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7612 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell -\pard\intbl\qc\fs18 \keepn\trhdr <30 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?30 to <60 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?60 to <90 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?90 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - Pre-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 5 Min Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.10 (0.01) \cell -\pard\intbl\qc\fs18 0.10 (0.00) \cell -\pard\intbl\qc\fs18 0.10 (0.01) \cell -\pard\intbl\qc\fs18 0.10 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.09, 0.11 \cell -\pard\intbl\qc\fs18 0.10, 0.11 \cell -\pard\intbl\qc\fs18 0.09, 0.11 \cell -\pard\intbl\qc\fs18 0.09, 0.11 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 5.2 \cell -\pard\intbl\qc\fs18 3.5 \cell -\pard\intbl\qc\fs18 5.5 \cell -\pard\intbl\qc\fs18 4.4 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.10, 0.10 \cell -\pard\intbl\qc\fs18 0.10, 0.11 \cell -\pard\intbl\qc\fs18 0.10, 0.10 \cell -\pard\intbl\qc\fs18 0.10, 0.10 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 30 Min Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.54 (0.03) \cell -\pard\intbl\qc\fs18 0.56 (0.02) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\pard\intbl\qc\fs18 0.54 (0.02) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.56 \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.54 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.56 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.54 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.51, 0.59 \cell -\pard\intbl\qc\fs18 0.53, 0.58 \cell -\pard\intbl\qc\fs18 0.51, 0.60 \cell -\pard\intbl\qc\fs18 0.50, 0.58 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 4.7 \cell -\pard\intbl\qc\fs18 3.2 \cell -\pard\intbl\qc\fs18 5.0 \cell -\pard\intbl\qc\fs18 4.0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.52, 0.56 \cell -\pard\intbl\qc\fs18 0.55, 0.58 \cell -\pard\intbl\qc\fs18 0.52, 0.56 \cell -\pard\intbl\qc\fs18 0.52, 0.55 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.93 (0.04) \cell -\pard\intbl\qc\fs18 0.95 (0.03) \cell -\pard\intbl\qc\fs18 0.93 (0.04) \cell -\pard\intbl\qc\fs18 0.92 (0.03) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.92 \cell -\pard\intbl\qc\fs18 0.96 \cell -\pard\intbl\qc\fs18 0.92 \cell -\pard\intbl\qc\fs18 0.92 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.95 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.92 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.87, 1.00 \cell -\pard\intbl\qc\fs18 0.91, 0.99 \cell -\pard\intbl\qc\fs18 0.88, 1.02 \cell -\pard\intbl\qc\fs18 0.86, 0.99 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 4.3 \cell -\pard\intbl\qc\fs18 2.9 \cell -\pard\intbl\qc\fs18 4.4 \cell -\pard\intbl\qc\fs18 3.5 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.90, 0.96 \cell -\pard\intbl\qc\fs18 0.93, 0.98 \cell -\pard\intbl\qc\fs18 0.90, 0.96 \cell -\pard\intbl\qc\fs18 0.89, 0.94 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1.5h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.20 (0.05) \cell -\pard\intbl\qc\fs18 1.23 (0.03) \cell -\pard\intbl\qc\fs18 1.20 (0.05) \cell -\pard\intbl\qc\fs18 1.19 (0.04) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.20 \cell -\pard\intbl\qc\fs18 1.24 \cell -\pard\intbl\qc\fs18 1.19 \cell -\pard\intbl\qc\fs18 1.19 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.20 \cell -\pard\intbl\qc\fs18 1.23 \cell -\pard\intbl\qc\fs18 1.20 \cell -\pard\intbl\qc\fs18 1.18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.13, 1.28 \cell -\pard\intbl\qc\fs18 1.19, 1.27 \cell -\pard\intbl\qc\fs18 1.14, 1.31 \cell -\pard\intbl\qc\fs18 1.12, 1.27 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 4.0 \cell -\pard\intbl\qc\fs18 2.7 \cell -\pard\intbl\qc\fs18 4.0 \cell -\pard\intbl\qc\fs18 3.2 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.16, 1.24 \cell -\pard\intbl\qc\fs18 1.20, 1.27 \cell -\pard\intbl\qc\fs18 1.17, 1.23 \cell -\pard\intbl\qc\fs18 1.16, 1.21 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 2h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.39 (0.05) \cell -\pard\intbl\qc\fs18 1.43 (0.04) \cell -\pard\intbl\qc\fs18 1.39 (0.05) \cell -\pard\intbl\qc\fs18 1.37 (0.04) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.39 \cell -\pard\intbl\qc\fs18 1.44 \cell -\pard\intbl\qc\fs18 1.37 \cell -\pard\intbl\qc\fs18 1.38 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.39 \cell -\pard\intbl\qc\fs18 1.42 \cell -\pard\intbl\qc\fs18 1.39 \cell -\pard\intbl\qc\fs18 1.37 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.32, 1.48 \cell -\pard\intbl\qc\fs18 1.38, 1.47 \cell -\pard\intbl\qc\fs18 1.33, 1.50 \cell -\pard\intbl\qc\fs18 1.31, 1.47 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 3.7 \cell -\pard\intbl\qc\fs18 2.6 \cell -\pard\intbl\qc\fs18 3.7 \cell -\pard\intbl\qc\fs18 2.9 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.35, 1.44 \cell -\pard\intbl\qc\fs18 1.38, 1.46 \cell -\pard\intbl\qc\fs18 1.36, 1.42 \cell -\pard\intbl\qc\fs18 1.35, 1.40 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 4h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.74 (0.06) \cell -\pard\intbl\qc\fs18 1.77 (0.05) \cell -\pard\intbl\qc\fs18 1.74 (0.05) \cell -\pard\intbl\qc\fs18 1.72 (0.05) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.73 \cell -\pard\intbl\qc\fs18 1.80 \cell -\pard\intbl\qc\fs18 1.73 \cell -\pard\intbl\qc\fs18 1.72 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.74 \cell -\pard\intbl\qc\fs18 1.77 \cell -\pard\intbl\qc\fs18 1.74 \cell -\pard\intbl\qc\fs18 1.72 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.66, 1.82 \cell -\pard\intbl\qc\fs18 1.70, 1.82 \cell -\pard\intbl\qc\fs18 1.67, 1.84 \cell -\pard\intbl\qc\fs18 1.65, 1.83 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 3.3 \cell -\pard\intbl\qc\fs18 2.6 \cell -\pard\intbl\qc\fs18 3.0 \cell -\pard\intbl\qc\fs18 2.6 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.69, 1.79 \cell -\pard\intbl\qc\fs18 1.74, 1.81 \cell -\pard\intbl\qc\fs18 1.69, 1.77 \cell -\pard\intbl\qc\fs18 1.68, 1.73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 0-6h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 26.99 (1.54) \cell -\pard\intbl\qc\fs18 26.43 (1.29) \cell -\pard\intbl\qc\fs18 26.74 (1.59) \cell -\pard\intbl\qc\fs18 26.91 (1.54) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 27.14 \cell -\pard\intbl\qc\fs18 26.53 \cell -\pard\intbl\qc\fs18 26.61 \cell -\pard\intbl\qc\fs18 27.34 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 26.95 \cell -\pard\intbl\qc\fs18 26.41 \cell -\pard\intbl\qc\fs18 26.70 \cell -\pard\intbl\qc\fs18 26.87 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 24.65, 29.18 \cell -\pard\intbl\qc\fs18 24.49, 28.66 \cell -\pard\intbl\qc\fs18 24.61, 29.12 \cell -\pard\intbl\qc\fs18 24.57, 29.19 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 5.7 \cell -\pard\intbl\qc\fs18 4.9 \cell -\pard\intbl\qc\fs18 6.0 \cell -\pard\intbl\qc\fs18 5.7 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 25.43, 28.33 \cell -\pard\intbl\qc\fs18 25.81, 27.10 \cell -\pard\intbl\qc\fs18 25.09, 28.28 \cell -\pard\intbl\qc\fs18 25.48, 28.31 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.83 (0.06) \cell -\pard\intbl\qc\fs18 1.86 (0.05) \cell -\pard\intbl\qc\fs18 1.82 (0.05) \cell -\pard\intbl\qc\fs18 1.80 (0.05) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.83 \cell -\pard\intbl\qc\fs18 1.89 \cell -\pard\intbl\qc\fs18 1.82 \cell -\pard\intbl\qc\fs18 1.80 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.83 \cell -\pard\intbl\qc\fs18 1.86 \cell -\pard\intbl\qc\fs18 1.82 \cell -\pard\intbl\qc\fs18 1.80 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.74, 1.91 \cell -\pard\intbl\qc\fs18 1.77, 1.90 \cell -\pard\intbl\qc\fs18 1.75, 1.92 \cell -\pard\intbl\qc\fs18 1.74, 1.91 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 3.2 \cell -\pard\intbl\qc\fs18 2.7 \cell -\pard\intbl\qc\fs18 2.8 \cell -\pard\intbl\qc\fs18 2.7 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.77, 1.88 \cell -\pard\intbl\qc\fs18 1.83, 1.90 \cell -\pard\intbl\qc\fs18 1.78, 1.86 \cell -\pard\intbl\qc\fs18 1.77, 1.83 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 8h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.85 (0.06) \cell -\pard\intbl\qc\fs18 1.88 (0.05) \cell -\pard\intbl\qc\fs18 1.84 (0.05) \cell -\pard\intbl\qc\fs18 1.82 (0.05) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.85 \cell -\pard\intbl\qc\fs18 1.91 \cell -\pard\intbl\qc\fs18 1.84 \cell -\pard\intbl\qc\fs18 1.82 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.85 \cell -\pard\intbl\qc\fs18 1.88 \cell -\pard\intbl\qc\fs18 1.84 \cell -\pard\intbl\qc\fs18 1.82 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.76, 1.93 \cell -\pard\intbl\qc\fs18 1.78, 1.92 \cell -\pard\intbl\qc\fs18 1.77, 1.94 \cell -\pard\intbl\qc\fs18 1.76, 1.93 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 3.2 \cell -\pard\intbl\qc\fs18 2.7 \cell -\pard\intbl\qc\fs18 2.8 \cell -\pard\intbl\qc\fs18 2.7 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.78, 1.90 \cell -\pard\intbl\qc\fs18 1.85, 1.92 \cell -\pard\intbl\qc\fs18 1.80, 1.88 \cell -\pard\intbl\qc\fs18 1.79, 1.85 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6-12h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 22.83 (1.72) \cell -\pard\intbl\qc\fs18 22.20 (1.45) \cell -\pard\intbl\qc\fs18 22.54 (1.78) \cell -\pard\intbl\qc\fs18 22.73 (1.72) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 23.00 \cell -\pard\intbl\qc\fs18 22.32 \cell -\pard\intbl\qc\fs18 22.41 \cell -\pard\intbl\qc\fs18 23.22 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 22.76 \cell -\pard\intbl\qc\fs18 22.16 \cell -\pard\intbl\qc\fs18 22.48 \cell -\pard\intbl\qc\fs18 22.67 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 20.19, 25.26 \cell -\pard\intbl\qc\fs18 20.01, 24.69 \cell -\pard\intbl\qc\fs18 20.15, 25.20 \cell -\pard\intbl\qc\fs18 20.11, 25.27 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 7.5 \cell -\pard\intbl\qc\fs18 6.5 \cell -\pard\intbl\qc\fs18 7.9 \cell -\pard\intbl\qc\fs18 7.6 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 21.08, 24.32 \cell -\pard\intbl\qc\fs18 21.50, 22.95 \cell -\pard\intbl\qc\fs18 20.70, 24.26 \cell -\pard\intbl\qc\fs18 21.14, 24.30 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.56 (0.04) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\pard\intbl\qc\fs18 0.55 (0.04) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.56 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.56 \cell -\pard\intbl\qc\fs18 0.55 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.56 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.49, 0.61 \cell -\pard\intbl\qc\fs18 0.49, 0.60 \cell -\pard\intbl\qc\fs18 0.50, 0.60 \cell -\pard\intbl\qc\fs18 0.49, 0.62 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 6.3 \cell -\pard\intbl\qc\fs18 6.0 \cell -\pard\intbl\qc\fs18 5.9 \cell -\pard\intbl\qc\fs18 6.5 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.53, 0.59 \cell -\pard\intbl\qc\fs18 0.55, 0.58 \cell -\pard\intbl\qc\fs18 0.53, 0.58 \cell -\pard\intbl\qc\fs18 0.52, 0.57 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 16h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.17 (0.02) \cell -\pard\intbl\qc\fs18 0.16 (0.02) \cell -\pard\intbl\qc\fs18 0.16 (0.02) \cell -\pard\intbl\qc\fs18 0.16 (0.02) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.17 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.17 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.14, 0.19 \cell -\pard\intbl\qc\fs18 0.13, 0.19 \cell -\pard\intbl\qc\fs18 0.14, 0.19 \cell -\pard\intbl\qc\fs18 0.13, 0.20 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 11.1 \cell -\pard\intbl\qc\fs18 10.2 \cell -\pard\intbl\qc\fs18 11.1 \cell -\pard\intbl\qc\fs18 11.5 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.15, 0.18 \cell -\pard\intbl\qc\fs18 0.16, 0.17 \cell -\pard\intbl\qc\fs18 0.15, 0.18 \cell -\pard\intbl\qc\fs18 0.15, 0.18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12-24h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 14.49 (2.09) \cell -\pard\intbl\qc\fs18 13.74 (1.76) \cell -\pard\intbl\qc\fs18 14.15 (2.16) \cell -\pard\intbl\qc\fs18 14.38 (2.09) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 14.72 \cell -\pard\intbl\qc\fs18 13.89 \cell -\pard\intbl\qc\fs18 14.00 \cell -\pard\intbl\qc\fs18 14.98 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 14.35 \cell -\pard\intbl\qc\fs18 13.64 \cell -\pard\intbl\qc\fs18 14.00 \cell -\pard\intbl\qc\fs18 14.23 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 11.29, 17.43 \cell -\pard\intbl\qc\fs18 11.07, 16.75 \cell -\pard\intbl\qc\fs18 11.24, 17.36 \cell -\pard\intbl\qc\fs18 11.18, 17.44 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 14.4 \cell -\pard\intbl\qc\fs18 12.8 \cell -\pard\intbl\qc\fs18 15.3 \cell -\pard\intbl\qc\fs18 14.5 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 12.38, 16.31 \cell -\pard\intbl\qc\fs18 12.90, 14.66 \cell -\pard\intbl\qc\fs18 11.91, 16.24 \cell -\pard\intbl\qc\fs18 12.45, 16.28 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.02 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 21.1 \cell -\pard\intbl\qc\fs18 19.1 \cell -\pard\intbl\qc\fs18 21.9 \cell -\pard\intbl\qc\fs18 21.6 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - Pre-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.02 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 21.1 \cell -\pard\intbl\qc\fs18 19.1 \cell -\pard\intbl\qc\fs18 21.9 \cell -\pard\intbl\qc\fs18 21.6 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 36h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24-48h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.33 (0.60) \cell -\pard\intbl\qc\fs18 0.13 (0.33) \cell -\pard\intbl\qc\fs18 0.29 (0.56) \cell -\pard\intbl\qc\fs18 0.28 (0.52) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 1.77 \cell -\pard\intbl\qc\fs18 0.00, 0.87 \cell -\pard\intbl\qc\fs18 0.00, 1.67 \cell -\pard\intbl\qc\fs18 0.00, 1.78 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 184.0 \cell -\pard\intbl\qc\fs18 254.2 \cell -\pard\intbl\qc\fs18 194.9 \cell -\pard\intbl\qc\fs18 189.2 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.40 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.18 \cell -\pard\intbl\qc\fs18 0.00, 0.24 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - 48h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - Pre-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2881 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7612 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tpk02part2/tpk02part2of2.rtf b/tests/testthat/_snaps/tpk02part2/tpk02part2of2.rtf deleted file mode 100644 index fce9a28d..00000000 --- a/tests/testthat/_snaps/tpk02part2/tpk02part2of2.rtf +++ /dev/null @@ -1,2608 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2881 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7612 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TPK02part2of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2881 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7612 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7612 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7612 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr [Body Weight (kg)] [Quartiles] \cell -\pard\intbl\qc\fs18 \keepn\trhdr [Body Weight (kg)] [Quartiles] \cell -\pard\intbl\qc\fs18 \keepn\trhdr [Body Weight (kg)] [Quartiles] \cell -\pard\intbl\qc\fs18 \keepn\trhdr [Body Weight (kg)] [Quartiles] \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2881 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4458 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6035 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7612 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell -\pard\intbl\qc\fs18 \keepn\trhdr <30 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?30 to <60 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?60 to <90 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?90 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - Pre-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\pard\intbl\qc\fs18 NA \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 5 Min Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.10 (0.01) \cell -\pard\intbl\qc\fs18 0.10 (0.01) \cell -\pard\intbl\qc\fs18 0.10 (0.01) \cell -\pard\intbl\qc\fs18 0.10 (0.01) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\pard\intbl\qc\fs18 0.10 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.09, 0.11 \cell -\pard\intbl\qc\fs18 0.09, 0.11 \cell -\pard\intbl\qc\fs18 0.09, 0.11 \cell -\pard\intbl\qc\fs18 0.09, 0.11 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 5.5 \cell -\pard\intbl\qc\fs18 5.3 \cell -\pard\intbl\qc\fs18 5.0 \cell -\pard\intbl\qc\fs18 5.4 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.10, 0.10 \cell -\pard\intbl\qc\fs18 0.10, 0.10 \cell -\pard\intbl\qc\fs18 0.10, 0.11 \cell -\pard\intbl\qc\fs18 0.10, 0.11 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 30 Min Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.54 (0.03) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\pard\intbl\qc\fs18 0.55 (0.02) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.55 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.54 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.50, 0.60 \cell -\pard\intbl\qc\fs18 0.50, 0.59 \cell -\pard\intbl\qc\fs18 0.50, 0.59 \cell -\pard\intbl\qc\fs18 0.50, 0.60 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 5.1 \cell -\pard\intbl\qc\fs18 4.9 \cell -\pard\intbl\qc\fs18 4.5 \cell -\pard\intbl\qc\fs18 4.9 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.52, 0.56 \cell -\pard\intbl\qc\fs18 0.53, 0.56 \cell -\pard\intbl\qc\fs18 0.54, 0.57 \cell -\pard\intbl\qc\fs18 0.53, 0.57 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.92 (0.04) \cell -\pard\intbl\qc\fs18 0.93 (0.04) \cell -\pard\intbl\qc\fs18 0.93 (0.04) \cell -\pard\intbl\qc\fs18 0.93 (0.04) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.92 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.93 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.92 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.93 \cell -\pard\intbl\qc\fs18 0.93 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.86, 1.01 \cell -\pard\intbl\qc\fs18 0.86, 0.99 \cell -\pard\intbl\qc\fs18 0.86, 1.00 \cell -\pard\intbl\qc\fs18 0.85, 1.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 4.8 \cell -\pard\intbl\qc\fs18 4.4 \cell -\pard\intbl\qc\fs18 4.0 \cell -\pard\intbl\qc\fs18 4.4 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.89, 0.96 \cell -\pard\intbl\qc\fs18 0.90, 0.96 \cell -\pard\intbl\qc\fs18 0.92, 0.96 \cell -\pard\intbl\qc\fs18 0.90, 0.97 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1.5h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.19 (0.05) \cell -\pard\intbl\qc\fs18 1.20 (0.05) \cell -\pard\intbl\qc\fs18 1.21 (0.04) \cell -\pard\intbl\qc\fs18 1.20 (0.05) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.19 \cell -\pard\intbl\qc\fs18 1.20 \cell -\pard\intbl\qc\fs18 1.21 \cell -\pard\intbl\qc\fs18 1.20 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.19 \cell -\pard\intbl\qc\fs18 1.20 \cell -\pard\intbl\qc\fs18 1.21 \cell -\pard\intbl\qc\fs18 1.20 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.11, 1.29 \cell -\pard\intbl\qc\fs18 1.12, 1.27 \cell -\pard\intbl\qc\fs18 1.12, 1.28 \cell -\pard\intbl\qc\fs18 1.11, 1.29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 4.5 \cell -\pard\intbl\qc\fs18 4.0 \cell -\pard\intbl\qc\fs18 3.6 \cell -\pard\intbl\qc\fs18 4.0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.15, 1.24 \cell -\pard\intbl\qc\fs18 1.16, 1.23 \cell -\pard\intbl\qc\fs18 1.19, 1.24 \cell -\pard\intbl\qc\fs18 1.17, 1.24 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 2h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.38 (0.06) \cell -\pard\intbl\qc\fs18 1.39 (0.05) \cell -\pard\intbl\qc\fs18 1.40 (0.05) \cell -\pard\intbl\qc\fs18 1.39 (0.05) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.37 \cell -\pard\intbl\qc\fs18 1.39 \cell -\pard\intbl\qc\fs18 1.40 \cell -\pard\intbl\qc\fs18 1.39 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.38 \cell -\pard\intbl\qc\fs18 1.39 \cell -\pard\intbl\qc\fs18 1.40 \cell -\pard\intbl\qc\fs18 1.39 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.30, 1.49 \cell -\pard\intbl\qc\fs18 1.31, 1.47 \cell -\pard\intbl\qc\fs18 1.31, 1.48 \cell -\pard\intbl\qc\fs18 1.29, 1.49 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 4.3 \cell -\pard\intbl\qc\fs18 3.8 \cell -\pard\intbl\qc\fs18 3.3 \cell -\pard\intbl\qc\fs18 3.7 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.33, 1.43 \cell -\pard\intbl\qc\fs18 1.35, 1.43 \cell -\pard\intbl\qc\fs18 1.37, 1.43 \cell -\pard\intbl\qc\fs18 1.36, 1.44 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 4h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.73 (0.07) \cell -\pard\intbl\qc\fs18 1.74 (0.06) \cell -\pard\intbl\qc\fs18 1.75 (0.05) \cell -\pard\intbl\qc\fs18 1.74 (0.05) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.70 \cell -\pard\intbl\qc\fs18 1.73 \cell -\pard\intbl\qc\fs18 1.75 \cell -\pard\intbl\qc\fs18 1.74 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.73 \cell -\pard\intbl\qc\fs18 1.73 \cell -\pard\intbl\qc\fs18 1.75 \cell -\pard\intbl\qc\fs18 1.74 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.65, 1.83 \cell -\pard\intbl\qc\fs18 1.66, 1.82 \cell -\pard\intbl\qc\fs18 1.66, 1.82 \cell -\pard\intbl\qc\fs18 1.64, 1.83 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 3.9 \cell -\pard\intbl\qc\fs18 3.2 \cell -\pard\intbl\qc\fs18 2.7 \cell -\pard\intbl\qc\fs18 3.1 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.67, 1.79 \cell -\pard\intbl\qc\fs18 1.69, 1.77 \cell -\pard\intbl\qc\fs18 1.72, 1.79 \cell -\pard\intbl\qc\fs18 1.70, 1.78 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 0-6h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 26.99 (1.30) \cell -\pard\intbl\qc\fs18 26.68 (1.48) \cell -\pard\intbl\qc\fs18 26.87 (1.56) \cell -\pard\intbl\qc\fs18 26.55 (1.45) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 27.03 \cell -\pard\intbl\qc\fs18 26.33 \cell -\pard\intbl\qc\fs18 26.59 \cell -\pard\intbl\qc\fs18 26.62 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 26.96 \cell -\pard\intbl\qc\fs18 26.65 \cell -\pard\intbl\qc\fs18 26.83 \cell -\pard\intbl\qc\fs18 26.51 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 24.64, 28.88 \cell -\pard\intbl\qc\fs18 24.59, 28.82 \cell -\pard\intbl\qc\fs18 24.60, 29.15 \cell -\pard\intbl\qc\fs18 24.53, 29.25 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 4.8 \cell -\pard\intbl\qc\fs18 5.5 \cell -\pard\intbl\qc\fs18 5.8 \cell -\pard\intbl\qc\fs18 5.5 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 25.92, 28.09 \cell -\pard\intbl\qc\fs18 25.43, 28.45 \cell -\pard\intbl\qc\fs18 25.50, 28.30 \cell -\pard\intbl\qc\fs18 25.43, 27.51 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.82 (0.07) \cell -\pard\intbl\qc\fs18 1.82 (0.06) \cell -\pard\intbl\qc\fs18 1.83 (0.05) \cell -\pard\intbl\qc\fs18 1.82 (0.05) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.77 \cell -\pard\intbl\qc\fs18 1.81 \cell -\pard\intbl\qc\fs18 1.85 \cell -\pard\intbl\qc\fs18 1.82 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.81 \cell -\pard\intbl\qc\fs18 1.82 \cell -\pard\intbl\qc\fs18 1.83 \cell -\pard\intbl\qc\fs18 1.82 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.74, 1.91 \cell -\pard\intbl\qc\fs18 1.74, 1.91 \cell -\pard\intbl\qc\fs18 1.75, 1.90 \cell -\pard\intbl\qc\fs18 1.73, 1.90 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 3.8 \cell -\pard\intbl\qc\fs18 3.0 \cell -\pard\intbl\qc\fs18 2.6 \cell -\pard\intbl\qc\fs18 2.9 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.75, 1.89 \cell -\pard\intbl\qc\fs18 1.79, 1.85 \cell -\pard\intbl\qc\fs18 1.80, 1.88 \cell -\pard\intbl\qc\fs18 1.78, 1.87 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 8h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 1.84 (0.07) \cell -\pard\intbl\qc\fs18 1.84 (0.06) \cell -\pard\intbl\qc\fs18 1.85 (0.05) \cell -\pard\intbl\qc\fs18 1.84 (0.05) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 1.79 \cell -\pard\intbl\qc\fs18 1.84 \cell -\pard\intbl\qc\fs18 1.86 \cell -\pard\intbl\qc\fs18 1.84 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 1.84 \cell -\pard\intbl\qc\fs18 1.84 \cell -\pard\intbl\qc\fs18 1.85 \cell -\pard\intbl\qc\fs18 1.84 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.76, 1.93 \cell -\pard\intbl\qc\fs18 1.76, 1.94 \cell -\pard\intbl\qc\fs18 1.78, 1.92 \cell -\pard\intbl\qc\fs18 1.75, 1.92 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 3.7 \cell -\pard\intbl\qc\fs18 3.0 \cell -\pard\intbl\qc\fs18 2.6 \cell -\pard\intbl\qc\fs18 2.8 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1.77, 1.91 \cell -\pard\intbl\qc\fs18 1.81, 1.88 \cell -\pard\intbl\qc\fs18 1.81, 1.90 \cell -\pard\intbl\qc\fs18 1.80, 1.89 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6-12h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 22.83 (1.45) \cell -\pard\intbl\qc\fs18 22.48 (1.65) \cell -\pard\intbl\qc\fs18 22.69 (1.75) \cell -\pard\intbl\qc\fs18 22.33 (1.62) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 22.87 \cell -\pard\intbl\qc\fs18 22.10 \cell -\pard\intbl\qc\fs18 22.39 \cell -\pard\intbl\qc\fs18 22.42 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 22.78 \cell -\pard\intbl\qc\fs18 22.42 \cell -\pard\intbl\qc\fs18 22.62 \cell -\pard\intbl\qc\fs18 22.27 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 20.19, 24.93 \cell -\pard\intbl\qc\fs18 20.12, 24.86 \cell -\pard\intbl\qc\fs18 20.14, 25.23 \cell -\pard\intbl\qc\fs18 20.06, 25.34 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 6.4 \cell -\pard\intbl\qc\fs18 7.4 \cell -\pard\intbl\qc\fs18 7.7 \cell -\pard\intbl\qc\fs18 7.3 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 21.63, 24.05 \cell -\pard\intbl\qc\fs18 21.08, 24.46 \cell -\pard\intbl\qc\fs18 21.16, 24.29 \cell -\pard\intbl\qc\fs18 21.08, 23.41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\pard\intbl\qc\fs18 0.56 (0.03) \cell -\pard\intbl\qc\fs18 0.55 (0.03) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.54 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.55 \cell -\pard\intbl\qc\fs18 0.54 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.49, 0.61 \cell -\pard\intbl\qc\fs18 0.50, 0.59 \cell -\pard\intbl\qc\fs18 0.51, 0.62 \cell -\pard\intbl\qc\fs18 0.50, 0.62 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 5.4 \cell -\pard\intbl\qc\fs18 5.5 \cell -\pard\intbl\qc\fs18 5.9 \cell -\pard\intbl\qc\fs18 5.2 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.54, 0.57 \cell -\pard\intbl\qc\fs18 0.53, 0.57 \cell -\pard\intbl\qc\fs18 0.54, 0.58 \cell -\pard\intbl\qc\fs18 0.53, 0.57 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 16h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.17 (0.02) \cell -\pard\intbl\qc\fs18 0.16 (0.02) \cell -\pard\intbl\qc\fs18 0.17 (0.02) \cell -\pard\intbl\qc\fs18 0.16 (0.02) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.17 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.17 \cell -\pard\intbl\qc\fs18 0.16 \cell -\pard\intbl\qc\fs18 0.17 \cell -\pard\intbl\qc\fs18 0.16 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.13, 0.19 \cell -\pard\intbl\qc\fs18 0.14, 0.19 \cell -\pard\intbl\qc\fs18 0.14, 0.20 \cell -\pard\intbl\qc\fs18 0.14, 0.20 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 9.1 \cell -\pard\intbl\qc\fs18 10.2 \cell -\pard\intbl\qc\fs18 11.0 \cell -\pard\intbl\qc\fs18 9.9 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.16, 0.18 \cell -\pard\intbl\qc\fs18 0.15, 0.18 \cell -\pard\intbl\qc\fs18 0.15, 0.18 \cell -\pard\intbl\qc\fs18 0.15, 0.17 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12-24h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 14.50 (1.76) \cell -\pard\intbl\qc\fs18 14.07 (2.00) \cell -\pard\intbl\qc\fs18 14.32 (2.12) \cell -\pard\intbl\qc\fs18 13.89 (1.97) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 14.56 \cell -\pard\intbl\qc\fs18 13.62 \cell -\pard\intbl\qc\fs18 13.97 \cell -\pard\intbl\qc\fs18 14.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 14.39 \cell -\pard\intbl\qc\fs18 13.94 \cell -\pard\intbl\qc\fs18 14.18 \cell -\pard\intbl\qc\fs18 13.75 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 11.28, 17.03 \cell -\pard\intbl\qc\fs18 11.20, 16.95 \cell -\pard\intbl\qc\fs18 11.22, 17.39 \cell -\pard\intbl\qc\fs18 11.13, 17.52 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 12.2 \cell -\pard\intbl\qc\fs18 14.2 \cell -\pard\intbl\qc\fs18 14.8 \cell -\pard\intbl\qc\fs18 14.2 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 13.04, 15.98 \cell -\pard\intbl\qc\fs18 12.38, 16.47 \cell -\pard\intbl\qc\fs18 12.47, 16.27 \cell -\pard\intbl\qc\fs18 12.37, 15.21 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.02 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\pard\intbl\qc\fs18 0.02 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 17.3 \cell -\pard\intbl\qc\fs18 20.2 \cell -\pard\intbl\qc\fs18 21.5 \cell -\pard\intbl\qc\fs18 20.1 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - Pre-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 40 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.02 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\pard\intbl\qc\fs18 0.02 (0.00) \cell -\pard\intbl\qc\fs18 0.01 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 17.3 \cell -\pard\intbl\qc\fs18 19.5 \cell -\pard\intbl\qc\fs18 21.5 \cell -\pard\intbl\qc\fs18 20.3 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\pard\intbl\qc\fs18 0.01, 0.02 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 36h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24-48h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.18 (0.40) \cell -\pard\intbl\qc\fs18 0.24 (0.41) \cell -\pard\intbl\qc\fs18 0.30 (0.57) \cell -\pard\intbl\qc\fs18 0.20 (0.52) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 0.02 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 1.24 \cell -\pard\intbl\qc\fs18 0.00, 1.13 \cell -\pard\intbl\qc\fs18 0.00, 1.71 \cell -\pard\intbl\qc\fs18 0.00, 1.89 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 220.2 \cell -\pard\intbl\qc\fs18 167.0 \cell -\pard\intbl\qc\fs18 190.7 \cell -\pard\intbl\qc\fs18 260.5 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.49 \cell -\pard\intbl\qc\fs18 0.00, 0.23 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - 48h Post-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - Pre-dose \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 18 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 39 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\pard\intbl\qc\fs18 0.00 (0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\pard\intbl\qc\fs18 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Geometric mean \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\pard\intbl\qc\fs18 0.01 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CV (%) \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\pard\intbl\qc\fs18 0.00, 0.00 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2881 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7612 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tpk03/tpk03.rtf b/tests/testthat/_snaps/tpk03/tpk03.rtf index 1918a5fb..de73c372 100644 --- a/tests/testthat/_snaps/tpk03/tpk03.rtf +++ b/tests/testthat/_snaps/tpk03/tpk03.rtf @@ -31,8 +31,8 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \row } @@ -43,8 +43,8 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell \pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell \pard\intbl\qc\fs18 \keepn\trhdr N=168 \cell \row } @@ -54,7 +54,7 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - Pre-dose \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, Pre-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -67,8 +67,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -79,8 +79,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Number of subjects with values below LLOQxMRD, n (%) \cell -\pard\intbl\qc\fs18 72 (100.0%) \cell \pard\intbl\qc\fs18 96 (100.0%) \cell +\pard\intbl\qc\fs18 72 (100.0%) \cell \pard\intbl\qc\fs18 168 (100.0%) \cell \row } @@ -102,7 +102,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 5 Min Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 5 Min Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -115,8 +115,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -150,7 +150,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 30 Min Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 30 Min Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -163,8 +163,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -198,7 +198,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 1h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -211,8 +211,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -246,7 +246,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 1.5h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 1.5h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -259,8 +259,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -294,7 +294,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 2h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 2h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -307,8 +307,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -342,7 +342,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 4h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 0-6h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -355,8 +355,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -390,7 +390,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 0-6h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 4h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -403,8 +403,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -438,7 +438,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 6h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -451,8 +451,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -486,7 +486,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 8h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 8h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -499,8 +499,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -534,7 +534,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 6-12h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 6-12h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -547,8 +547,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -582,7 +582,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 12h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -595,8 +595,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -630,7 +630,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 16h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 16h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -643,8 +643,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -678,7 +678,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1 - 12-24h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 1, 12-24h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -691,8 +691,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -726,7 +726,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, Pre-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -739,9 +739,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 94 \cell \pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 168 \cell +\pard\intbl\qc\fs18 166 \cell \row } @@ -774,7 +774,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - Pre-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 24h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -787,9 +787,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 96 \cell \pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 94 \cell -\pard\intbl\qc\fs18 166 \cell +\pard\intbl\qc\fs18 168 \cell \row } @@ -822,7 +822,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 36h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 36h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -835,8 +835,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -847,8 +847,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Number of subjects with values below LLOQxMRD, n (%) \cell -\pard\intbl\qc\fs18 72 (100.0%) \cell \pard\intbl\qc\fs18 96 (100.0%) \cell +\pard\intbl\qc\fs18 72 (100.0%) \cell \pard\intbl\qc\fs18 168 (100.0%) \cell \row } @@ -870,7 +870,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2 - 24-48h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 2, 24-48h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -883,8 +883,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 72 \cell \pard\intbl\qc\fs18 168 \cell \row } @@ -895,8 +895,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Number of subjects with values below LLOQxMRD, n (%) \cell -\pard\intbl\qc\fs18 51 (70.8%) \cell \pard\intbl\qc\fs18 76 (79.2%) \cell +\pard\intbl\qc\fs18 51 (70.8%) \cell \pard\intbl\qc\fs18 127 (75.6%) \cell \row } @@ -918,7 +918,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - 48h Post-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3, Pre-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -931,9 +931,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 92 \cell \pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 96 \cell -\pard\intbl\qc\fs18 168 \cell +\pard\intbl\qc\fs18 164 \cell \row } @@ -943,9 +943,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Number of subjects with values below LLOQxMRD, n (%) \cell +\pard\intbl\qc\fs18 92 (95.8%) \cell \pard\intbl\qc\fs18 72 (100.0%) \cell -\pard\intbl\qc\fs18 96 (100.0%) \cell -\pard\intbl\qc\fs18 168 (100.0%) \cell +\pard\intbl\qc\fs18 164 (97.6%) \cell \row } @@ -966,7 +966,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3 - Pre-dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Day 3, 48h Post-dose \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -979,9 +979,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 96 \cell \pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 92 \cell -\pard\intbl\qc\fs18 164 \cell +\pard\intbl\qc\fs18 168 \cell \row } @@ -991,9 +991,9 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4907 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6959 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Number of subjects with values below LLOQxMRD, n (%) \cell +\pard\intbl\qc\fs18 96 (100.0%) \cell \pard\intbl\qc\fs18 72 (100.0%) \cell -\pard\intbl\qc\fs18 92 (95.8%) \cell -\pard\intbl\qc\fs18 164 (97.6%) \cell +\pard\intbl\qc\fs18 168 (100.0%) \cell \row } diff --git a/tests/testthat/_snaps/tpkada01/tpkada01.rtf b/tests/testthat/_snaps/tpkada01/tpkada01.rtf new file mode 100644 index 00000000..bca66a25 --- /dev/null +++ b/tests/testthat/_snaps/tpkada01/tpkada01.rtf @@ -0,0 +1,2342 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2841 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5265 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7855 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10278 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TPKADA01:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2841 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5265 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7855 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10278 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5265 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7855 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx10278 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=72 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs18 \keepn\trhdr Positive for Treatment-emergentAntibodies to Active Study Agent\super b\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr Negative for Treatment-emergentAntibodies to Active Study Agent\super c\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr Positive for Treatment-emergentAntibodies to Active Study Agent\super b\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr Negative for Treatment-emergentAntibodies to Active Study Agent\super c\nosupersub \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with evaluable samples\super a\nosupersub \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - Pre-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 NA \cell +\pard\intbl\qc\fs18 NA \cell +\pard\intbl\qc\fs18 NA \cell +\pard\intbl\qc\fs18 NA \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 5 Min Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.101 (0.00506) \cell +\pard\intbl\qc\fs18 0.0997 (0.00502) \cell +\pard\intbl\qc\fs18 0.101 (0.00481) \cell +\pard\intbl\qc\fs18 0.101 (0.00545) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.100 \cell +\pard\intbl\qc\fs18 0.0998 \cell +\pard\intbl\qc\fs18 0.101 \cell +\pard\intbl\qc\fs18 0.101 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.0925, 0.109) \cell +\pard\intbl\qc\fs18 (0.0910, 0.109) \cell +\pard\intbl\qc\fs18 (0.0932, 0.109) \cell +\pard\intbl\qc\fs18 (0.0912, 0.112) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 5.0 \cell +\pard\intbl\qc\fs18 5.0 \cell +\pard\intbl\qc\fs18 4.8 \cell +\pard\intbl\qc\fs18 5.4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.0968, 0.104) \cell +\pard\intbl\qc\fs18 (0.0958, 0.103) \cell +\pard\intbl\qc\fs18 (0.0960, 0.105) \cell +\pard\intbl\qc\fs18 (0.0959, 0.103) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 30 Min Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.545 (0.0253) \cell +\pard\intbl\qc\fs18 0.541 (0.0248) \cell +\pard\intbl\qc\fs18 0.545 (0.0240) \cell +\pard\intbl\qc\fs18 0.545 (0.0269) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.542 \cell +\pard\intbl\qc\fs18 0.541 \cell +\pard\intbl\qc\fs18 0.549 \cell +\pard\intbl\qc\fs18 0.546 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.505, 0.586) \cell +\pard\intbl\qc\fs18 (0.497, 0.588) \cell +\pard\intbl\qc\fs18 (0.509, 0.589) \cell +\pard\intbl\qc\fs18 (0.499, 0.603) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 4.6 \cell +\pard\intbl\qc\fs18 4.6 \cell +\pard\intbl\qc\fs18 4.4 \cell +\pard\intbl\qc\fs18 4.9 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.526, 0.565) \cell +\pard\intbl\qc\fs18 (0.520, 0.558) \cell +\pard\intbl\qc\fs18 (0.523, 0.567) \cell +\pard\intbl\qc\fs18 (0.524, 0.556) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 1h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.930 (0.0394) \cell +\pard\intbl\qc\fs18 0.924 (0.0382) \cell +\pard\intbl\qc\fs18 0.929 (0.0375) \cell +\pard\intbl\qc\fs18 0.929 (0.0415) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.925 \cell +\pard\intbl\qc\fs18 0.922 \cell +\pard\intbl\qc\fs18 0.932 \cell +\pard\intbl\qc\fs18 0.930 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.865, 0.992) \cell +\pard\intbl\qc\fs18 (0.855, 0.996) \cell +\pard\intbl\qc\fs18 (0.873, 0.996) \cell +\pard\intbl\qc\fs18 (0.859, 1.02) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 4.2 \cell +\pard\intbl\qc\fs18 4.1 \cell +\pard\intbl\qc\fs18 4.0 \cell +\pard\intbl\qc\fs18 4.5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.899, 0.960) \cell +\pard\intbl\qc\fs18 (0.888, 0.950) \cell +\pard\intbl\qc\fs18 (0.899, 0.965) \cell +\pard\intbl\qc\fs18 (0.901, 0.948) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 1.5h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.20 (0.0470) \cell +\pard\intbl\qc\fs18 1.19 (0.0452) \cell +\pard\intbl\qc\fs18 1.20 (0.0451) \cell +\pard\intbl\qc\fs18 1.20 (0.0492) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 1.20 \cell +\pard\intbl\qc\fs18 1.20 \cell +\pard\intbl\qc\fs18 1.20 \cell +\pard\intbl\qc\fs18 1.20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.12, 1.27) \cell +\pard\intbl\qc\fs18 (1.11, 1.28) \cell +\pard\intbl\qc\fs18 (1.13, 1.28) \cell +\pard\intbl\qc\fs18 (1.12, 1.31) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 3.9 \cell +\pard\intbl\qc\fs18 3.8 \cell +\pard\intbl\qc\fs18 3.8 \cell +\pard\intbl\qc\fs18 4.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.16, 1.24) \cell +\pard\intbl\qc\fs18 (1.15, 1.22) \cell +\pard\intbl\qc\fs18 (1.16, 1.24) \cell +\pard\intbl\qc\fs18 (1.17, 1.23) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 2h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.39 (0.0510) \cell +\pard\intbl\qc\fs18 1.39 (0.0487) \cell +\pard\intbl\qc\fs18 1.39 (0.0493) \cell +\pard\intbl\qc\fs18 1.39 (0.0532) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 1.40 \cell +\pard\intbl\qc\fs18 1.39 \cell +\pard\intbl\qc\fs18 1.38 \cell +\pard\intbl\qc\fs18 1.38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.31, 1.47) \cell +\pard\intbl\qc\fs18 (1.30, 1.48) \cell +\pard\intbl\qc\fs18 (1.31, 1.47) \cell +\pard\intbl\qc\fs18 (1.31, 1.50) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 3.7 \cell +\pard\intbl\qc\fs18 3.5 \cell +\pard\intbl\qc\fs18 3.5 \cell +\pard\intbl\qc\fs18 3.8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.35, 1.44) \cell +\pard\intbl\qc\fs18 (1.34, 1.42) \cell +\pard\intbl\qc\fs18 (1.35, 1.44) \cell +\pard\intbl\qc\fs18 (1.35, 1.42) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 0-6h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 26.7 (1.29) \cell +\pard\intbl\qc\fs18 27.1 (1.44) \cell +\pard\intbl\qc\fs18 26.7 (1.37) \cell +\pard\intbl\qc\fs18 26.6 (1.59) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 26.7 \cell +\pard\intbl\qc\fs18 27.0 \cell +\pard\intbl\qc\fs18 26.6 \cell +\pard\intbl\qc\fs18 26.2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (24.6, 29.2) \cell +\pard\intbl\qc\fs18 (24.6, 29.2) \cell +\pard\intbl\qc\fs18 (24.6, 29.1) \cell +\pard\intbl\qc\fs18 (24.5, 29.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 4.8 \cell +\pard\intbl\qc\fs18 5.3 \cell +\pard\intbl\qc\fs18 5.1 \cell +\pard\intbl\qc\fs18 6.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (25.8, 27.5) \cell +\pard\intbl\qc\fs18 (25.7, 28.5) \cell +\pard\intbl\qc\fs18 (25.5, 27.9) \cell +\pard\intbl\qc\fs18 (25.0, 28.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 4h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.74 (0.0549) \cell +\pard\intbl\qc\fs18 1.73 (0.0519) \cell +\pard\intbl\qc\fs18 1.73 (0.0555) \cell +\pard\intbl\qc\fs18 1.73 (0.0577) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 1.72 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.65, 1.82) \cell +\pard\intbl\qc\fs18 (1.65, 1.82) \cell +\pard\intbl\qc\fs18 (1.65, 1.82) \cell +\pard\intbl\qc\fs18 (1.65, 1.84) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 3.2 \cell +\pard\intbl\qc\fs18 3.0 \cell +\pard\intbl\qc\fs18 3.2 \cell +\pard\intbl\qc\fs18 3.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.69, 1.78) \cell +\pard\intbl\qc\fs18 (1.69, 1.78) \cell +\pard\intbl\qc\fs18 (1.69, 1.79) \cell +\pard\intbl\qc\fs18 (1.68, 1.79) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 6h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.82 (0.0552) \cell +\pard\intbl\qc\fs18 1.82 (0.0525) \cell +\pard\intbl\qc\fs18 1.82 (0.0573) \cell +\pard\intbl\qc\fs18 1.81 (0.0590) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 1.82 \cell +\pard\intbl\qc\fs18 1.81 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.73, 1.91) \cell +\pard\intbl\qc\fs18 (1.74, 1.90) \cell +\pard\intbl\qc\fs18 (1.74, 1.91) \cell +\pard\intbl\qc\fs18 (1.74, 1.92) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 3.0 \cell +\pard\intbl\qc\fs18 2.9 \cell +\pard\intbl\qc\fs18 3.1 \cell +\pard\intbl\qc\fs18 3.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.78, 1.87) \cell +\pard\intbl\qc\fs18 (1.77, 1.87) \cell +\pard\intbl\qc\fs18 (1.77, 1.88) \cell +\pard\intbl\qc\fs18 (1.76, 1.87) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 8h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.84 (0.0552) \cell +\pard\intbl\qc\fs18 1.84 (0.0528) \cell +\pard\intbl\qc\fs18 1.84 (0.0579) \cell +\pard\intbl\qc\fs18 1.83 (0.0595) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 1.84 \cell +\pard\intbl\qc\fs18 1.83 \cell +\pard\intbl\qc\fs18 1.84 \cell +\pard\intbl\qc\fs18 1.83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.75, 1.94) \cell +\pard\intbl\qc\fs18 (1.76, 1.92) \cell +\pard\intbl\qc\fs18 (1.76, 1.93) \cell +\pard\intbl\qc\fs18 (1.76, 1.94) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 3.0 \cell +\pard\intbl\qc\fs18 2.9 \cell +\pard\intbl\qc\fs18 3.1 \cell +\pard\intbl\qc\fs18 3.2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.80, 1.89) \cell +\pard\intbl\qc\fs18 (1.79, 1.90) \cell +\pard\intbl\qc\fs18 (1.79, 1.90) \cell +\pard\intbl\qc\fs18 (1.78, 1.90) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 6-12h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 22.5 (1.44) \cell +\pard\intbl\qc\fs18 22.9 (1.61) \cell +\pard\intbl\qc\fs18 22.5 (1.54) \cell +\pard\intbl\qc\fs18 22.4 (1.78) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 22.5 \cell +\pard\intbl\qc\fs18 22.8 \cell +\pard\intbl\qc\fs18 22.4 \cell +\pard\intbl\qc\fs18 22.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (20.1, 25.2) \cell +\pard\intbl\qc\fs18 (20.1, 25.3) \cell +\pard\intbl\qc\fs18 (20.1, 25.2) \cell +\pard\intbl\qc\fs18 (20.0, 25.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 6.4 \cell +\pard\intbl\qc\fs18 7.0 \cell +\pard\intbl\qc\fs18 6.8 \cell +\pard\intbl\qc\fs18 7.9 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (21.5, 23.4) \cell +\pard\intbl\qc\fs18 (21.4, 24.6) \cell +\pard\intbl\qc\fs18 (21.2, 23.8) \cell +\pard\intbl\qc\fs18 (20.6, 24.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 12h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.550 (0.0272) \cell +\pard\intbl\qc\fs18 0.556 (0.0307) \cell +\pard\intbl\qc\fs18 0.549 (0.0317) \cell +\pard\intbl\qc\fs18 0.544 (0.0350) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.547 \cell +\pard\intbl\qc\fs18 0.553 \cell +\pard\intbl\qc\fs18 0.554 \cell +\pard\intbl\qc\fs18 0.544 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.510, 0.620) \cell +\pard\intbl\qc\fs18 (0.499, 0.617) \cell +\pard\intbl\qc\fs18 (0.494, 0.601) \cell +\pard\intbl\qc\fs18 (0.486, 0.619) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 5.0 \cell +\pard\intbl\qc\fs18 5.5 \cell +\pard\intbl\qc\fs18 5.8 \cell +\pard\intbl\qc\fs18 6.4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.532, 0.567) \cell +\pard\intbl\qc\fs18 (0.536, 0.579) \cell +\pard\intbl\qc\fs18 (0.526, 0.575) \cell +\pard\intbl\qc\fs18 (0.521, 0.574) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 16h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.164 (0.0147) \cell +\pard\intbl\qc\fs18 0.167 (0.0168) \cell +\pard\intbl\qc\fs18 0.163 (0.0165) \cell +\pard\intbl\qc\fs18 0.161 (0.0186) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.163 \cell +\pard\intbl\qc\fs18 0.166 \cell +\pard\intbl\qc\fs18 0.164 \cell +\pard\intbl\qc\fs18 0.159 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.141, 0.200) \cell +\pard\intbl\qc\fs18 (0.137, 0.197) \cell +\pard\intbl\qc\fs18 (0.137, 0.193) \cell +\pard\intbl\qc\fs18 (0.134, 0.198) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 9.0 \cell +\pard\intbl\qc\fs18 10.0 \cell +\pard\intbl\qc\fs18 10.1 \cell +\pard\intbl\qc\fs18 11.6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.153, 0.171) \cell +\pard\intbl\qc\fs18 (0.154, 0.180) \cell +\pard\intbl\qc\fs18 (0.151, 0.178) \cell +\pard\intbl\qc\fs18 (0.146, 0.174) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1 - 12-24h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 14.2 (1.75) \cell +\pard\intbl\qc\fs18 14.6 (1.95) \cell +\pard\intbl\qc\fs18 14.1 (1.86) \cell +\pard\intbl\qc\fs18 13.9 (2.15) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 14.1 \cell +\pard\intbl\qc\fs18 14.5 \cell +\pard\intbl\qc\fs18 13.9 \cell +\pard\intbl\qc\fs18 13.5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (11.2, 17.4) \cell +\pard\intbl\qc\fs18 (11.2, 17.5) \cell +\pard\intbl\qc\fs18 (11.2, 17.3) \cell +\pard\intbl\qc\fs18 (11.1, 17.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 12.3 \cell +\pard\intbl\qc\fs18 13.3 \cell +\pard\intbl\qc\fs18 13.2 \cell +\pard\intbl\qc\fs18 15.5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (12.9, 15.2) \cell +\pard\intbl\qc\fs18 (12.8, 16.6) \cell +\pard\intbl\qc\fs18 (12.5, 15.7) \cell +\pard\intbl\qc\fs18 (11.8, 15.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 2 - Pre-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.0146 (0.00258) \cell +\pard\intbl\qc\fs18 0.0152 (0.00294) \cell +\pard\intbl\qc\fs18 0.0146 (0.00281) \cell +\pard\intbl\qc\fs18 0.0143 (0.00322) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.0149 \cell +\pard\intbl\qc\fs18 0.0148 \cell +\pard\intbl\qc\fs18 0.0143 \cell +\pard\intbl\qc\fs18 0.0134 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.0107, 0.0207) \cell +\pard\intbl\qc\fs18 (0.0104, 0.0204) \cell +\pard\intbl\qc\fs18 (0.0103, 0.0199) \cell +\pard\intbl\qc\fs18 (0.0100, 0.0203) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 17.7 \cell +\pard\intbl\qc\fs18 19.3 \cell +\pard\intbl\qc\fs18 19.3 \cell +\pard\intbl\qc\fs18 22.5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.0127, 0.0161) \cell +\pard\intbl\qc\fs18 (0.0124, 0.0178) \cell +\pard\intbl\qc\fs18 (0.0124, 0.0167) \cell +\pard\intbl\qc\fs18 (0.0111, 0.0165) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 2 - 24h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.0146 (0.00258) \cell +\pard\intbl\qc\fs18 0.0153 (0.00296) \cell +\pard\intbl\qc\fs18 0.0146 (0.00281) \cell +\pard\intbl\qc\fs18 0.0143 (0.00322) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.0149 \cell +\pard\intbl\qc\fs18 0.0149 \cell +\pard\intbl\qc\fs18 0.0143 \cell +\pard\intbl\qc\fs18 0.0134 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.0107, 0.0207) \cell +\pard\intbl\qc\fs18 (0.0104, 0.0204) \cell +\pard\intbl\qc\fs18 (0.0103, 0.0199) \cell +\pard\intbl\qc\fs18 (0.0100, 0.0203) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 17.7 \cell +\pard\intbl\qc\fs18 19.3 \cell +\pard\intbl\qc\fs18 19.3 \cell +\pard\intbl\qc\fs18 22.5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.0127, 0.0161) \cell +\pard\intbl\qc\fs18 (0.0124, 0.0178) \cell +\pard\intbl\qc\fs18 (0.0124, 0.0167) \cell +\pard\intbl\qc\fs18 (0.0111, 0.0165) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 2 - 36h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 2 - 24-48h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.149 (0.416) \cell +\pard\intbl\qc\fs18 0.325 (0.544) \cell +\pard\intbl\qc\fs18 0.201 (0.451) \cell +\pard\intbl\qc\fs18 0.250 (0.555) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 1.73) \cell +\pard\intbl\qc\fs18 (0.00500, 1.79) \cell +\pard\intbl\qc\fs18 (0.00500, 1.65) \cell +\pard\intbl\qc\fs18 (0.00500, 1.78) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 279.7 \cell +\pard\intbl\qc\fs18 167.2 \cell +\pard\intbl\qc\fs18 224.4 \cell +\pard\intbl\qc\fs18 222.3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.650) \cell +\pard\intbl\qc\fs18 (0.00500, 0.0609) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 3 - Pre-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 3 - 48h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 CV (%) \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\pard\intbl\qc\fs18 0.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2841 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5265 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7855 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10278 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2841 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5265 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7855 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10278 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5265 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7855 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10278 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tpkada01titer/tpkada01titer.rtf b/tests/testthat/_snaps/tpkada01titer/tpkada01titer.rtf new file mode 100644 index 00000000..5a93ba43 --- /dev/null +++ b/tests/testthat/_snaps/tpkada01titer/tpkada01titer.rtf @@ -0,0 +1,2650 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4499 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6139 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7780 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9420 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11061 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TPKADA01titer:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4499 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6139 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7780 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9420 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11061 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Peak Titers for Subjects Positive for Treatment-emergent Antibodies to Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Negative for Treatment-emergent Antibodies to Active Study Agent\super a\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr Positive for Treatment-emergent Antibodies to Active Study Agent\super b\nosupersub \cell +\pard\intbl\qc\fs18 \keepn\trhdr <10 \cell +\pard\intbl\qc\fs18 \keepn\trhdr 10 to <100 \cell +\pard\intbl\qc\fs18 \keepn\trhdr 100 to <1000 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805?1000 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=76 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=41 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=35 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=23 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=27 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with evaluable samples\super c\nosupersub \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, Pre-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\pard\intbl\qc\fs18 0 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\pard\intbl\qc\fs18 (0, 0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 5 Min Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.100 (0.00520) \cell +\pard\intbl\qc\fs18 0.101 (0.00488) \cell +\pard\intbl\qc\fs18 0.100 (0.00383) \cell +\pard\intbl\qc\fs18 0.101 (0.00526) \cell +\pard\intbl\qc\fs18 0.101 (0.00613) \cell +\pard\intbl\qc\fs18 0.0998 (0.00534) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.100 \cell +\pard\intbl\qc\fs18 0.101 \cell +\pard\intbl\qc\fs18 0.100 \cell +\pard\intbl\qc\fs18 0.101 \cell +\pard\intbl\qc\fs18 0.101 \cell +\pard\intbl\qc\fs18 0.100 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.0910, 0.112) \cell +\pard\intbl\qc\fs18 (0.0925, 0.109) \cell +\pard\intbl\qc\fs18 (0.0931, 0.107) \cell +\pard\intbl\qc\fs18 (0.0921, 0.111) \cell +\pard\intbl\qc\fs18 (0.0912, 0.112) \cell +\pard\intbl\qc\fs18 (0.0910, 0.110) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.0958, 0.103) \cell +\pard\intbl\qc\fs18 (0.0962, 0.104) \cell +\pard\intbl\qc\fs18 (0.0968, 0.103) \cell +\pard\intbl\qc\fs18 (0.0966, 0.104) \cell +\pard\intbl\qc\fs18 (0.0957, 0.107) \cell +\pard\intbl\qc\fs18 (0.0951, 0.104) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 30 Min Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.543 (0.0257) \cell +\pard\intbl\qc\fs18 0.545 (0.0244) \cell +\pard\intbl\qc\fs18 0.542 (0.0188) \cell +\pard\intbl\qc\fs18 0.546 (0.0259) \cell +\pard\intbl\qc\fs18 0.546 (0.0303) \cell +\pard\intbl\qc\fs18 0.542 (0.0267) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.543 \cell +\pard\intbl\qc\fs18 0.547 \cell +\pard\intbl\qc\fs18 0.543 \cell +\pard\intbl\qc\fs18 0.547 \cell +\pard\intbl\qc\fs18 0.544 \cell +\pard\intbl\qc\fs18 0.541 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.497, 0.603) \cell +\pard\intbl\qc\fs18 (0.505, 0.589) \cell +\pard\intbl\qc\fs18 (0.507, 0.579) \cell +\pard\intbl\qc\fs18 (0.503, 0.595) \cell +\pard\intbl\qc\fs18 (0.499, 0.603) \cell +\pard\intbl\qc\fs18 (0.497, 0.592) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.520, 0.557) \cell +\pard\intbl\qc\fs18 (0.525, 0.565) \cell +\pard\intbl\qc\fs18 (0.526, 0.555) \cell +\pard\intbl\qc\fs18 (0.529, 0.564) \cell +\pard\intbl\qc\fs18 (0.520, 0.575) \cell +\pard\intbl\qc\fs18 (0.517, 0.564) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 1h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.926 (0.0396) \cell +\pard\intbl\qc\fs18 0.930 (0.0380) \cell +\pard\intbl\qc\fs18 0.924 (0.0291) \cell +\pard\intbl\qc\fs18 0.932 (0.0396) \cell +\pard\intbl\qc\fs18 0.931 (0.0467) \cell +\pard\intbl\qc\fs18 0.924 (0.0418) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.926 \cell +\pard\intbl\qc\fs18 0.931 \cell +\pard\intbl\qc\fs18 0.926 \cell +\pard\intbl\qc\fs18 0.931 \cell +\pard\intbl\qc\fs18 0.926 \cell +\pard\intbl\qc\fs18 0.923 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.855, 1.02) \cell +\pard\intbl\qc\fs18 (0.865, 0.996) \cell +\pard\intbl\qc\fs18 (0.869, 0.984) \cell +\pard\intbl\qc\fs18 (0.864, 1.01) \cell +\pard\intbl\qc\fs18 (0.859, 1.02) \cell +\pard\intbl\qc\fs18 (0.855, 1.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.894, 0.949) \cell +\pard\intbl\qc\fs18 (0.899, 0.963) \cell +\pard\intbl\qc\fs18 (0.900, 0.943) \cell +\pard\intbl\qc\fs18 (0.910, 0.959) \cell +\pard\intbl\qc\fs18 (0.889, 0.975) \cell +\pard\intbl\qc\fs18 (0.884, 0.958) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 1.5h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.20 (0.0468) \cell +\pard\intbl\qc\fs18 1.20 (0.0455) \cell +\pard\intbl\qc\fs18 1.19 (0.0347) \cell +\pard\intbl\qc\fs18 1.20 (0.0465) \cell +\pard\intbl\qc\fs18 1.20 (0.0549) \cell +\pard\intbl\qc\fs18 1.19 (0.0501) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 1.20 \cell +\pard\intbl\qc\fs18 1.20 \cell +\pard\intbl\qc\fs18 1.19 \cell +\pard\intbl\qc\fs18 1.20 \cell +\pard\intbl\qc\fs18 1.20 \cell +\pard\intbl\qc\fs18 1.20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.11, 1.31) \cell +\pard\intbl\qc\fs18 (1.12, 1.28) \cell +\pard\intbl\qc\fs18 (1.13, 1.27) \cell +\pard\intbl\qc\fs18 (1.12, 1.29) \cell +\pard\intbl\qc\fs18 (1.12, 1.31) \cell +\pard\intbl\qc\fs18 (1.11, 1.28) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.16, 1.22) \cell +\pard\intbl\qc\fs18 (1.16, 1.24) \cell +\pard\intbl\qc\fs18 (1.17, 1.21) \cell +\pard\intbl\qc\fs18 (1.18, 1.23) \cell +\pard\intbl\qc\fs18 (1.15, 1.25) \cell +\pard\intbl\qc\fs18 (1.15, 1.24) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 2h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.39 (0.0504) \cell +\pard\intbl\qc\fs18 1.39 (0.0496) \cell +\pard\intbl\qc\fs18 1.38 (0.0382) \cell +\pard\intbl\qc\fs18 1.40 (0.0497) \cell +\pard\intbl\qc\fs18 1.39 (0.0586) \cell +\pard\intbl\qc\fs18 1.39 (0.0547) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 1.38 \cell +\pard\intbl\qc\fs18 1.39 \cell +\pard\intbl\qc\fs18 1.38 \cell +\pard\intbl\qc\fs18 1.40 \cell +\pard\intbl\qc\fs18 1.39 \cell +\pard\intbl\qc\fs18 1.38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.30, 1.50) \cell +\pard\intbl\qc\fs18 (1.31, 1.47) \cell +\pard\intbl\qc\fs18 (1.31, 1.46) \cell +\pard\intbl\qc\fs18 (1.31, 1.48) \cell +\pard\intbl\qc\fs18 (1.31, 1.50) \cell +\pard\intbl\qc\fs18 (1.30, 1.48) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.35, 1.42) \cell +\pard\intbl\qc\fs18 (1.35, 1.44) \cell +\pard\intbl\qc\fs18 (1.35, 1.40) \cell +\pard\intbl\qc\fs18 (1.36, 1.43) \cell +\pard\intbl\qc\fs18 (1.34, 1.45) \cell +\pard\intbl\qc\fs18 (1.33, 1.43) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 0-6h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 26.9 (1.52) \cell +\pard\intbl\qc\fs18 26.7 (1.31) \cell +\pard\intbl\qc\fs18 26.7 (1.34) \cell +\pard\intbl\qc\fs18 26.9 (1.50) \cell +\pard\intbl\qc\fs18 26.8 (1.57) \cell +\pard\intbl\qc\fs18 27.0 (1.46) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 26.9 \cell +\pard\intbl\qc\fs18 26.6 \cell +\pard\intbl\qc\fs18 26.6 \cell +\pard\intbl\qc\fs18 27.0 \cell +\pard\intbl\qc\fs18 26.5 \cell +\pard\intbl\qc\fs18 27.1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (24.5, 29.2) \cell +\pard\intbl\qc\fs18 (24.6, 29.2) \cell +\pard\intbl\qc\fs18 (24.5, 29.1) \cell +\pard\intbl\qc\fs18 (24.6, 29.2) \cell +\pard\intbl\qc\fs18 (24.6, 29.2) \cell +\pard\intbl\qc\fs18 (24.6, 29.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (25.5, 28.3) \cell +\pard\intbl\qc\fs18 (25.8, 27.6) \cell +\pard\intbl\qc\fs18 (25.5, 27.8) \cell +\pard\intbl\qc\fs18 (25.8, 28.1) \cell +\pard\intbl\qc\fs18 (25.4, 28.5) \cell +\pard\intbl\qc\fs18 (25.7, 28.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 4h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.73 (0.0542) \cell +\pard\intbl\qc\fs18 1.74 (0.0545) \cell +\pard\intbl\qc\fs18 1.72 (0.0454) \cell +\pard\intbl\qc\fs18 1.74 (0.0517) \cell +\pard\intbl\qc\fs18 1.74 (0.0592) \cell +\pard\intbl\qc\fs18 1.73 (0.0604) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 1.73 \cell +\pard\intbl\qc\fs18 1.72 \cell +\pard\intbl\qc\fs18 1.74 \cell +\pard\intbl\qc\fs18 1.72 \cell +\pard\intbl\qc\fs18 1.73 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.65, 1.84) \cell +\pard\intbl\qc\fs18 (1.65, 1.82) \cell +\pard\intbl\qc\fs18 (1.65, 1.81) \cell +\pard\intbl\qc\fs18 (1.65, 1.82) \cell +\pard\intbl\qc\fs18 (1.65, 1.84) \cell +\pard\intbl\qc\fs18 (1.65, 1.82) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.68, 1.78) \cell +\pard\intbl\qc\fs18 (1.69, 1.79) \cell +\pard\intbl\qc\fs18 (1.68, 1.75) \cell +\pard\intbl\qc\fs18 (1.72, 1.79) \cell +\pard\intbl\qc\fs18 (1.68, 1.79) \cell +\pard\intbl\qc\fs18 (1.67, 1.79) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 6h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.82 (0.0552) \cell +\pard\intbl\qc\fs18 1.82 (0.0555) \cell +\pard\intbl\qc\fs18 1.81 (0.0489) \cell +\pard\intbl\qc\fs18 1.83 (0.0519) \cell +\pard\intbl\qc\fs18 1.82 (0.0575) \cell +\pard\intbl\qc\fs18 1.82 (0.0617) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 1.82 \cell +\pard\intbl\qc\fs18 1.81 \cell +\pard\intbl\qc\fs18 1.82 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.74, 1.92) \cell +\pard\intbl\qc\fs18 (1.73, 1.91) \cell +\pard\intbl\qc\fs18 (1.74, 1.90) \cell +\pard\intbl\qc\fs18 (1.73, 1.91) \cell +\pard\intbl\qc\fs18 (1.75, 1.92) \cell +\pard\intbl\qc\fs18 (1.74, 1.91) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.77, 1.87) \cell +\pard\intbl\qc\fs18 (1.77, 1.88) \cell +\pard\intbl\qc\fs18 (1.76, 1.84) \cell +\pard\intbl\qc\fs18 (1.79, 1.88) \cell +\pard\intbl\qc\fs18 (1.77, 1.87) \cell +\pard\intbl\qc\fs18 (1.76, 1.88) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 8h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.84 (0.0556) \cell +\pard\intbl\qc\fs18 1.84 (0.0558) \cell +\pard\intbl\qc\fs18 1.83 (0.0503) \cell +\pard\intbl\qc\fs18 1.85 (0.0520) \cell +\pard\intbl\qc\fs18 1.84 (0.0568) \cell +\pard\intbl\qc\fs18 1.84 (0.0620) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 1.83 \cell +\pard\intbl\qc\fs18 1.84 \cell +\pard\intbl\qc\fs18 1.83 \cell +\pard\intbl\qc\fs18 1.85 \cell +\pard\intbl\qc\fs18 1.84 \cell +\pard\intbl\qc\fs18 1.83 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (1.76, 1.94) \cell +\pard\intbl\qc\fs18 (1.75, 1.94) \cell +\pard\intbl\qc\fs18 (1.76, 1.92) \cell +\pard\intbl\qc\fs18 (1.75, 1.93) \cell +\pard\intbl\qc\fs18 (1.77, 1.94) \cell +\pard\intbl\qc\fs18 (1.76, 1.94) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (1.78, 1.90) \cell +\pard\intbl\qc\fs18 (1.80, 1.90) \cell +\pard\intbl\qc\fs18 (1.78, 1.86) \cell +\pard\intbl\qc\fs18 (1.81, 1.90) \cell +\pard\intbl\qc\fs18 (1.79, 1.90) \cell +\pard\intbl\qc\fs18 (1.78, 1.90) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 6-12h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 22.7 (1.70) \cell +\pard\intbl\qc\fs18 22.5 (1.47) \cell +\pard\intbl\qc\fs18 22.5 (1.50) \cell +\pard\intbl\qc\fs18 22.7 (1.68) \cell +\pard\intbl\qc\fs18 22.6 (1.76) \cell +\pard\intbl\qc\fs18 22.8 (1.63) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 22.8 \cell +\pard\intbl\qc\fs18 22.4 \cell +\pard\intbl\qc\fs18 22.4 \cell +\pard\intbl\qc\fs18 22.8 \cell +\pard\intbl\qc\fs18 22.2 \cell +\pard\intbl\qc\fs18 22.9 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (20.0, 25.3) \cell +\pard\intbl\qc\fs18 (20.1, 25.2) \cell +\pard\intbl\qc\fs18 (20.0, 25.2) \cell +\pard\intbl\qc\fs18 (20.1, 25.3) \cell +\pard\intbl\qc\fs18 (20.1, 25.3) \cell +\pard\intbl\qc\fs18 (20.2, 25.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (21.2, 24.3) \cell +\pard\intbl\qc\fs18 (21.5, 23.5) \cell +\pard\intbl\qc\fs18 (21.1, 23.8) \cell +\pard\intbl\qc\fs18 (21.5, 24.1) \cell +\pard\intbl\qc\fs18 (21.0, 24.5) \cell +\pard\intbl\qc\fs18 (21.3, 24.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 12h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.551 (0.0330) \cell +\pard\intbl\qc\fs18 0.549 (0.0291) \cell +\pard\intbl\qc\fs18 0.544 (0.0333) \cell +\pard\intbl\qc\fs18 0.556 (0.0314) \cell +\pard\intbl\qc\fs18 0.550 (0.0288) \cell +\pard\intbl\qc\fs18 0.553 (0.0323) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.548 \cell +\pard\intbl\qc\fs18 0.549 \cell +\pard\intbl\qc\fs18 0.547 \cell +\pard\intbl\qc\fs18 0.550 \cell +\pard\intbl\qc\fs18 0.545 \cell +\pard\intbl\qc\fs18 0.555 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.486, 0.619) \cell +\pard\intbl\qc\fs18 (0.494, 0.620) \cell +\pard\intbl\qc\fs18 (0.486, 0.619) \cell +\pard\intbl\qc\fs18 (0.499, 0.612) \cell +\pard\intbl\qc\fs18 (0.503, 0.617) \cell +\pard\intbl\qc\fs18 (0.494, 0.620) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.529, 0.575) \cell +\pard\intbl\qc\fs18 (0.531, 0.570) \cell +\pard\intbl\qc\fs18 (0.518, 0.564) \cell +\pard\intbl\qc\fs18 (0.531, 0.582) \cell +\pard\intbl\qc\fs18 (0.532, 0.570) \cell +\pard\intbl\qc\fs18 (0.530, 0.581) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 16h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.165 (0.0178) \cell +\pard\intbl\qc\fs18 0.163 (0.0154) \cell +\pard\intbl\qc\fs18 0.162 (0.0170) \cell +\pard\intbl\qc\fs18 0.166 (0.0174) \cell +\pard\intbl\qc\fs18 0.164 (0.0168) \cell +\pard\intbl\qc\fs18 0.166 (0.0170) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.164 \cell +\pard\intbl\qc\fs18 0.163 \cell +\pard\intbl\qc\fs18 0.162 \cell +\pard\intbl\qc\fs18 0.168 \cell +\pard\intbl\qc\fs18 0.161 \cell +\pard\intbl\qc\fs18 0.165 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.134, 0.198) \cell +\pard\intbl\qc\fs18 (0.137, 0.200) \cell +\pard\intbl\qc\fs18 (0.134, 0.198) \cell +\pard\intbl\qc\fs18 (0.137, 0.197) \cell +\pard\intbl\qc\fs18 (0.140, 0.197) \cell +\pard\intbl\qc\fs18 (0.136, 0.200) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.151, 0.180) \cell +\pard\intbl\qc\fs18 (0.153, 0.176) \cell +\pard\intbl\qc\fs18 (0.149, 0.171) \cell +\pard\intbl\qc\fs18 (0.150, 0.179) \cell +\pard\intbl\qc\fs18 (0.150, 0.180) \cell +\pard\intbl\qc\fs18 (0.155, 0.180) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 1, 12-24h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 14.3 (2.06) \cell +\pard\intbl\qc\fs18 14.1 (1.78) \cell +\pard\intbl\qc\fs18 14.1 (1.82) \cell +\pard\intbl\qc\fs18 14.4 (2.03) \cell +\pard\intbl\qc\fs18 14.2 (2.13) \cell +\pard\intbl\qc\fs18 14.5 (1.97) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 14.4 \cell +\pard\intbl\qc\fs18 14.0 \cell +\pard\intbl\qc\fs18 14.0 \cell +\pard\intbl\qc\fs18 14.5 \cell +\pard\intbl\qc\fs18 13.8 \cell +\pard\intbl\qc\fs18 14.6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (11.1, 17.5) \cell +\pard\intbl\qc\fs18 (11.2, 17.4) \cell +\pard\intbl\qc\fs18 (11.1, 17.3) \cell +\pard\intbl\qc\fs18 (11.2, 17.5) \cell +\pard\intbl\qc\fs18 (11.2, 17.4) \cell +\pard\intbl\qc\fs18 (11.3, 17.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (12.5, 16.2) \cell +\pard\intbl\qc\fs18 (12.9, 15.3) \cell +\pard\intbl\qc\fs18 (12.4, 15.7) \cell +\pard\intbl\qc\fs18 (12.9, 16.0) \cell +\pard\intbl\qc\fs18 (12.3, 16.5) \cell +\pard\intbl\qc\fs18 (12.7, 16.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 2, Pre-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 75 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.0148 (0.00308) \cell +\pard\intbl\qc\fs18 0.0146 (0.00266) \cell +\pard\intbl\qc\fs18 0.0142 (0.00275) \cell +\pard\intbl\qc\fs18 0.0150 (0.00306) \cell +\pard\intbl\qc\fs18 0.0147 (0.00306) \cell +\pard\intbl\qc\fs18 0.0151 (0.00296) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.0143 \cell +\pard\intbl\qc\fs18 0.0144 \cell +\pard\intbl\qc\fs18 0.0142 \cell +\pard\intbl\qc\fs18 0.0149 \cell +\pard\intbl\qc\fs18 0.0142 \cell +\pard\intbl\qc\fs18 0.0149 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.0100, 0.0204) \cell +\pard\intbl\qc\fs18 (0.0103, 0.0207) \cell +\pard\intbl\qc\fs18 (0.0100, 0.0203) \cell +\pard\intbl\qc\fs18 (0.0104, 0.0204) \cell +\pard\intbl\qc\fs18 (0.0106, 0.0202) \cell +\pard\intbl\qc\fs18 (0.0103, 0.0207) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.0122, 0.0177) \cell +\pard\intbl\qc\fs18 (0.0127, 0.0161) \cell +\pard\intbl\qc\fs18 (0.0123, 0.0161) \cell +\pard\intbl\qc\fs18 (0.0124, 0.0178) \cell +\pard\intbl\qc\fs18 (0.0120, 0.0180) \cell +\pard\intbl\qc\fs18 (0.0127, 0.0177) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 2, 24h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.0149 (0.00310) \cell +\pard\intbl\qc\fs18 0.0146 (0.00266) \cell +\pard\intbl\qc\fs18 0.0144 (0.00283) \cell +\pard\intbl\qc\fs18 0.0150 (0.00306) \cell +\pard\intbl\qc\fs18 0.0147 (0.00306) \cell +\pard\intbl\qc\fs18 0.0151 (0.00296) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.0145 \cell +\pard\intbl\qc\fs18 0.0144 \cell +\pard\intbl\qc\fs18 0.0142 \cell +\pard\intbl\qc\fs18 0.0149 \cell +\pard\intbl\qc\fs18 0.0142 \cell +\pard\intbl\qc\fs18 0.0149 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.0100, 0.0204) \cell +\pard\intbl\qc\fs18 (0.0103, 0.0207) \cell +\pard\intbl\qc\fs18 (0.0100, 0.0203) \cell +\pard\intbl\qc\fs18 (0.0104, 0.0204) \cell +\pard\intbl\qc\fs18 (0.0106, 0.0202) \cell +\pard\intbl\qc\fs18 (0.0103, 0.0207) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.0123, 0.0177) \cell +\pard\intbl\qc\fs18 (0.0127, 0.0161) \cell +\pard\intbl\qc\fs18 (0.0123, 0.0162) \cell +\pard\intbl\qc\fs18 (0.0124, 0.0178) \cell +\pard\intbl\qc\fs18 (0.0120, 0.0180) \cell +\pard\intbl\qc\fs18 (0.0127, 0.0177) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 2, 36h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 2, 24-48h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.291 (0.547) \cell +\pard\intbl\qc\fs18 0.174 (0.429) \cell +\pard\intbl\qc\fs18 0.175 (0.441) \cell +\pard\intbl\qc\fs18 0.279 (0.558) \cell +\pard\intbl\qc\fs18 0.294 (0.511) \cell +\pard\intbl\qc\fs18 0.275 (0.557) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 1.79) \cell +\pard\intbl\qc\fs18 (0.00500, 1.73) \cell +\pard\intbl\qc\fs18 (0.00500, 1.65) \cell +\pard\intbl\qc\fs18 (0.00500, 1.79) \cell +\pard\intbl\qc\fs18 (0.00500, 1.78) \cell +\pard\intbl\qc\fs18 (0.00500, 1.77) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.173) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.535) \cell +\pard\intbl\qc\fs18 (0.00500, 0.173) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 3, Pre-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Day 3, 48h Post-dose \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\pard\intbl\qc\fs18 0.00500 (0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\pard\intbl\qc\fs18 0.00500 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Min, max \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4499 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6139 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9420 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11061 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\pard\intbl\qc\fs18 (0.00500, 0.00500) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4499 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6139 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7780 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9420 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11061 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4499 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6139 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9420 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11061 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae01a/tsfae01a.rtf b/tests/testthat/_snaps/tsfae01a/tsfae01a.rtf old mode 100755 new mode 100644 index 0f422c8c..23e4c676 --- a/tests/testthat/_snaps/tsfae01a/tsfae01a.rtf +++ b/tests/testthat/_snaps/tsfae01a/tsfae01a.rtf @@ -3,30 +3,34 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10241 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7049 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8446 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10640 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE01a:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2858 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6192 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7859 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10241 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2860 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7049 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8446 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10640 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell @@ -35,31 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10241 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10640 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Event, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -67,369 +75,433 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SAE \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 43 (58.9%) \cell -\pard\intbl\qc\fs18 27 (45.8%) \cell -\pard\intbl\qc\fs18 35.4 (18.9, 51.9) \cell -\pard\intbl\qc\fs18 13.1 (-3.9, 30.1) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 AEs \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 96 (81.4%) \cell +\pard\intbl\qc\fs18 38 (59.4%) \cell +\pard\intbl\qc\fs18 15.3 (-0.7, 31.2) \cell +\pard\intbl\qc\fs18 30.8 (16.3, 45.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 With fatal outcome \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SAEs \cell +\pard\intbl\qc\fs18 43 (64.2%) \cell +\pard\intbl\qc\fs18 41 (80.4%) \cell +\pard\intbl\qc\fs18 84 (71.2%) \cell +\pard\intbl\qc\fs18 25 (39.1%) \cell +\pard\intbl\qc\fs18 25.1 (8.5, 41.7) \cell +\pard\intbl\qc\fs18 41.3 (25.2, 57.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Life-threatening \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Related AEs \cell +\pard\intbl\qc\fs18 48 (71.6%) \cell +\pard\intbl\qc\fs18 45 (88.2%) \cell +\pard\intbl\qc\fs18 93 (78.8%) \cell +\pard\intbl\qc\fs18 34 (53.1%) \cell +\pard\intbl\qc\fs18 18.5 (2.2, 34.8) \cell +\pard\intbl\qc\fs18 35.1 (20.0, 50.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Requiring or prolonging hospitalization \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Related SAEs \cell +\pard\intbl\qc\fs18 39 (58.2%) \cell +\pard\intbl\qc\fs18 39 (76.5%) \cell +\pard\intbl\qc\fs18 78 (66.1%) \cell +\pard\intbl\qc\fs18 22 (34.4%) \cell +\pard\intbl\qc\fs18 23.8 (7.3, 40.4) \cell +\pard\intbl\qc\fs18 42.1 (25.6, 58.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Resulting in persistent or significant disability/incapacity \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 AE leading to permanent discontinuation of study treatment \cell +\pard\intbl\qc\fs18 16 (23.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 34 (28.8%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\pard\intbl\qc\fs18 8.3 (-5.3, 21.8) \cell +\pard\intbl\qc\fs18 19.7 (3.8, 35.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Congenital anomaly or birth defect \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Related AEs leading to death \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 43 (58.9%) \cell -\pard\intbl\qc\fs18 27 (45.8%) \cell -\pard\intbl\qc\fs18 35.4 (18.9, 51.9) \cell -\pard\intbl\qc\fs18 13.1 (-3.9, 30.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Worst severity \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Mild \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\pard\intbl\qc\fs18 -0.9 (-14.6, 12.8) \cell +\pard\intbl\qc\fs18 -4.6 (-18.7, 9.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Moderate \cell +\pard\intbl\qc\fs18 22 (32.8%) \cell +\pard\intbl\qc\fs18 24 (47.1%) \cell +\pard\intbl\qc\fs18 46 (39.0%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\pard\intbl\qc\fs18 17.2 (2.9, 31.5) \cell +\pard\intbl\qc\fs18 31.4 (15.1, 47.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Severe \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 4.3 (-3.3, 11.9) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 AE leading to permanent discontinuation of study treatment \cell -\pard\intbl\qc\fs18 21 (39.6%) \cell -\pard\intbl\qc\fs18 15 (20.5%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\pard\intbl\qc\fs18 22.7 (6.4, 39.0) \cell -\pard\intbl\qc\fs18 3.6 (-9.7, 16.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Missing \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\pard\intbl\qc\fs18 -5.4 (-18.4, 7.6) \cell +\pard\intbl\qc\fs18 1.3 (-13.7, 16.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 AE leading to dose modification of study treatment \cell -\pard\intbl\qc\fs18 50 (94.3%) \cell -\pard\intbl\qc\fs18 48 (65.8%) \cell -\pard\intbl\qc\fs18 28 (47.5%) \cell -\pard\intbl\qc\fs18 46.9 (32.7, 61.1) \cell -\pard\intbl\qc\fs18 18.3 (1.5, 35.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Interruption of study treatment \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 22 (30.1%) \cell -\pard\intbl\qc\fs18 11 (18.6%) \cell -\pard\intbl\qc\fs18 24.8 (8.1, 41.4) \cell -\pard\intbl\qc\fs18 11.5 (-3.0, 26.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 AE leading to dose modification of study treatment\super a,b\nosupersub \cell +\pard\intbl\qc\fs18 45 (67.2%) \cell +\pard\intbl\qc\fs18 37 (72.5%) \cell +\pard\intbl\qc\fs18 82 (69.5%) \cell +\pard\intbl\qc\fs18 30 (46.9%) \cell +\pard\intbl\qc\fs18 20.3 (3.7, 36.9) \cell +\pard\intbl\qc\fs18 25.7 (8.4, 43.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Reduction of study treatment \cell -\pard\intbl\qc\fs18 24 (45.3%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\pard\intbl\qc\fs18 28.3 (11.9, 44.8) \cell -\pard\intbl\qc\fs18 7.7 (-6.1, 21.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Drug interrupted \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 19 (37.3%) \cell +\pard\intbl\qc\fs18 38 (32.2%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\pard\intbl\qc\fs18 12.7 (-1.3, 26.7) \cell +\pard\intbl\qc\fs18 21.6 (5.7, 37.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose Rate Reduced \cell -\pard\intbl\qc\fs18 25 (47.2%) \cell -\pard\intbl\qc\fs18 20 (27.4%) \cell -\pard\intbl\qc\fs18 8 (13.6%) \cell -\pard\intbl\qc\fs18 33.6 (17.6, 49.6) \cell -\pard\intbl\qc\fs18 13.8 (0.4, 27.3) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 21 (31.3%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 39 (33.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 14.2 (-0.3, 28.6) \cell +\pard\intbl\qc\fs18 18.1 (2.1, 34.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose Increased \cell -\pard\intbl\qc\fs18 24 (45.3%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 23.2 (6.2, 40.3) \cell -\pard\intbl\qc\fs18 2.6 (-11.9, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose rate reduced \cell +\pard\intbl\qc\fs18 21 (31.3%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 39 (33.1%) \cell +\pard\intbl\qc\fs18 15 (23.4%) \cell +\pard\intbl\qc\fs18 7.9 (-7.3, 23.1) \cell +\pard\intbl\qc\fs18 11.9 (-4.9, 28.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Unknown \cell -\pard\intbl\qc\fs18 18 (34.0%) \cell -\pard\intbl\qc\fs18 25 (34.2%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 27.2 (12.9, 41.5) \cell -\pard\intbl\qc\fs18 27.5 (14.8, 40.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose increased \cell +\pard\intbl\qc\fs18 22 (32.8%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 40 (33.9%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\pard\intbl\qc\fs18 17.2 (2.9, 31.5) \cell +\pard\intbl\qc\fs18 19.7 (3.8, 35.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Any AE\super a\nosupersub \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\pard\intbl\qc\fs18 40.3 (26.6, 54.0) \cell -\pard\intbl\qc\fs18 19.4 (3.3, 35.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Mild \cell -\pard\intbl\qc\fs18 22 (41.5%) \cell -\pard\intbl\qc\fs18 20 (27.4%) \cell -\pard\intbl\qc\fs18 22 (37.3%) \cell -\pard\intbl\qc\fs18 4.2 (-13.9, 22.3) \cell -\pard\intbl\qc\fs18 -9.9 (-25.9, 6.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SAE classification\super b\nosupersub \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Moderate \cell -\pard\intbl\qc\fs18 29 (54.7%) \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\pard\intbl\qc\fs18 37.8 (21.3, 54.2) \cell -\pard\intbl\qc\fs18 18.7 (4.1, 33.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Requires or prolongs hospitalization \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10241 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 10.6 (2.4, 18.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other medically important event \cell +\pard\intbl\qc\fs18 43 (64.2%) \cell +\pard\intbl\qc\fs18 41 (80.4%) \cell +\pard\intbl\qc\fs18 84 (71.2%) \cell +\pard\intbl\qc\fs18 25 (39.1%) \cell +\pard\intbl\qc\fs18 25.1 (8.5, 41.7) \cell +\pard\intbl\qc\fs18 41.3 (25.2, 57.5) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10241 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7049 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8446 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10640 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10241 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsfae01b/tsfae01b.rtf b/tests/testthat/_snaps/tsfae01b/tsfae01b.rtf old mode 100755 new mode 100644 index 615e1fcc..109dd155 --- a/tests/testthat/_snaps/tsfae01b/tsfae01b.rtf +++ b/tests/testthat/_snaps/tsfae01b/tsfae01b.rtf @@ -3,30 +3,34 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4438 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6045 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7652 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10176 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2815 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5699 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7140 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8582 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10642 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE01b:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2831 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4438 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6045 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7652 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10176 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2815 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5699 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7140 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8582 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10642 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell @@ -35,31 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10176 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10642 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Event, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -67,124 +75,140 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SAE \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 43 (58.9%) \cell -\pard\intbl\qc\fs18 27 (45.8%) \cell -\pard\intbl\qc\fs18 35.4 (18.9, 51.9) \cell -\pard\intbl\qc\fs18 13.1 (-3.9, 30.1) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 AEs \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 96 (81.4%) \cell +\pard\intbl\qc\fs18 38 (59.4%) \cell +\pard\intbl\qc\fs18 15.3 (-0.7, 31.2) \cell +\pard\intbl\qc\fs18 30.8 (16.3, 45.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 With fatal outcome \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SAEs \cell +\pard\intbl\qc\fs18 43 (64.2%) \cell +\pard\intbl\qc\fs18 41 (80.4%) \cell +\pard\intbl\qc\fs18 84 (71.2%) \cell +\pard\intbl\qc\fs18 25 (39.1%) \cell +\pard\intbl\qc\fs18 25.1 (8.5, 41.7) \cell +\pard\intbl\qc\fs18 41.3 (25.2, 57.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Life-threatening \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Related AEs \cell +\pard\intbl\qc\fs18 48 (71.6%) \cell +\pard\intbl\qc\fs18 45 (88.2%) \cell +\pard\intbl\qc\fs18 93 (78.8%) \cell +\pard\intbl\qc\fs18 34 (53.1%) \cell +\pard\intbl\qc\fs18 18.5 (2.2, 34.8) \cell +\pard\intbl\qc\fs18 35.1 (20.0, 50.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Requiring or prolonging hospitalization \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Related SAEs \cell +\pard\intbl\qc\fs18 39 (58.2%) \cell +\pard\intbl\qc\fs18 39 (76.5%) \cell +\pard\intbl\qc\fs18 78 (66.1%) \cell +\pard\intbl\qc\fs18 22 (34.4%) \cell +\pard\intbl\qc\fs18 23.8 (7.3, 40.4) \cell +\pard\intbl\qc\fs18 42.1 (25.6, 58.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Resulting in persistent or significant disability/incapacity \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 AE leading to permanent discontinuation of study treatment \cell +\pard\intbl\qc\fs18 16 (23.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 34 (28.8%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\pard\intbl\qc\fs18 8.3 (-5.3, 21.8) \cell +\pard\intbl\qc\fs18 19.7 (3.8, 35.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Congenital anomaly or birth defect \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Related AEs leading to death \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 43 (58.9%) \cell -\pard\intbl\qc\fs18 27 (45.8%) \cell -\pard\intbl\qc\fs18 35.4 (18.9, 51.9) \cell -\pard\intbl\qc\fs18 13.1 (-3.9, 30.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Worst toxicity grade\super a\nosupersub \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -195,257 +219,343 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 AE leading to permanent discontinuation of study treatment \cell -\pard\intbl\qc\fs18 21 (39.6%) \cell -\pard\intbl\qc\fs18 15 (20.5%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\pard\intbl\qc\fs18 22.7 (6.4, 39.0) \cell -\pard\intbl\qc\fs18 3.6 (-9.7, 16.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 AE leading to dose modification of study treatment \cell -\pard\intbl\qc\fs18 46 (86.8%) \cell -\pard\intbl\qc\fs18 42 (57.5%) \cell -\pard\intbl\qc\fs18 23 (39.0%) \cell -\pard\intbl\qc\fs18 47.8 (32.4, 63.2) \cell -\pard\intbl\qc\fs18 18.6 (1.7, 35.4) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 8.6 (-1.2, 18.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Interruption of study treatment \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 22 (30.1%) \cell -\pard\intbl\qc\fs18 11 (18.6%) \cell -\pard\intbl\qc\fs18 24.8 (8.1, 41.4) \cell -\pard\intbl\qc\fs18 11.5 (-3.0, 26.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 5.5 (-6.2, 17.2) \cell +\pard\intbl\qc\fs18 0.8 (-10.9, 12.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Reduction of study treatment \cell -\pard\intbl\qc\fs18 24 (45.3%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\pard\intbl\qc\fs18 28.3 (11.9, 44.8) \cell -\pard\intbl\qc\fs18 7.7 (-6.1, 21.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 45 (38.1%) \cell +\pard\intbl\qc\fs18 15 (23.4%) \cell +\pard\intbl\qc\fs18 10.9 (-4.5, 26.3) \cell +\pard\intbl\qc\fs18 19.7 (2.6, 36.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose Increased \cell -\pard\intbl\qc\fs18 24 (45.3%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 23.2 (6.2, 40.3) \cell -\pard\intbl\qc\fs18 2.6 (-11.9, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Missing \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 0.7 (-12.3, 13.8) \cell +\pard\intbl\qc\fs18 0.5 (-13.5, 14.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Unknown \cell -\pard\intbl\qc\fs18 18 (34.0%) \cell -\pard\intbl\qc\fs18 25 (34.2%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 27.2 (12.9, 41.5) \cell -\pard\intbl\qc\fs18 27.5 (14.8, 40.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805? Grade 3 \cell +\pard\intbl\qc\fs18 35 (52.2%) \cell +\pard\intbl\qc\fs18 34 (66.7%) \cell +\pard\intbl\qc\fs18 69 (58.5%) \cell +\pard\intbl\qc\fs18 24 (37.5%) \cell +\pard\intbl\qc\fs18 14.7 (-2.1, 31.6) \cell +\pard\intbl\qc\fs18 29.2 (11.6, 46.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Any AE\super a\nosupersub \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 54 (74.0%) \cell -\pard\intbl\qc\fs18 30 (50.8%) \cell -\pard\intbl\qc\fs18 45.4 (31.6, 59.1) \cell -\pard\intbl\qc\fs18 23.1 (6.9, 39.4) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 AE leading to dose modification of study treatment\super b,c\nosupersub \cell +\pard\intbl\qc\fs18 45 (67.2%) \cell +\pard\intbl\qc\fs18 37 (72.5%) \cell +\pard\intbl\qc\fs18 82 (69.5%) \cell +\pard\intbl\qc\fs18 30 (46.9%) \cell +\pard\intbl\qc\fs18 20.3 (3.7, 36.9) \cell +\pard\intbl\qc\fs18 25.7 (8.4, 43.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 -8.5 (-15.6, -1.4) \cell -\pard\intbl\qc\fs18 -4.4 (-12.8, 4.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Drug interrupted \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 19 (37.3%) \cell +\pard\intbl\qc\fs18 38 (32.2%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\pard\intbl\qc\fs18 12.7 (-1.3, 26.7) \cell +\pard\intbl\qc\fs18 21.6 (5.7, 37.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 9.8 (-0.4, 20.0) \cell -\pard\intbl\qc\fs18 7.6 (-1.0, 16.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 21 (31.3%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 39 (33.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 14.2 (-0.3, 28.6) \cell +\pard\intbl\qc\fs18 18.1 (2.1, 34.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 -0.5 (-12.4, 11.3) \cell -\pard\intbl\qc\fs18 -0.9 (-11.8, 10.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose rate reduced \cell +\pard\intbl\qc\fs18 21 (31.3%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 39 (33.1%) \cell +\pard\intbl\qc\fs18 15 (23.4%) \cell +\pard\intbl\qc\fs18 7.9 (-7.3, 23.1) \cell +\pard\intbl\qc\fs18 11.9 (-4.9, 28.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 16 (21.9%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 14.2 (0.8, 27.5) \cell -\pard\intbl\qc\fs18 13.4 (1.6, 25.3) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose increased \cell +\pard\intbl\qc\fs18 22 (32.8%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 40 (33.9%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\pard\intbl\qc\fs18 17.2 (2.9, 31.5) \cell +\pard\intbl\qc\fs18 19.7 (3.8, 35.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4438 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6045 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7652 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 26 (49.1%) \cell -\pard\intbl\qc\fs18 19 (26.0%) \cell -\pard\intbl\qc\fs18 11 (18.6%) \cell -\pard\intbl\qc\fs18 30.4 (13.7, 47.1) \cell -\pard\intbl\qc\fs18 7.4 (-6.8, 21.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4438 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6045 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7652 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10176 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SAE classification\super c\nosupersub \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Requires or prolongs hospitalization \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10642 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other medically important event \cell +\pard\intbl\qc\fs18 43 (64.2%) \cell +\pard\intbl\qc\fs18 41 (80.4%) \cell +\pard\intbl\qc\fs18 84 (71.2%) \cell +\pard\intbl\qc\fs18 25 (39.1%) \cell +\pard\intbl\qc\fs18 25.1 (8.5, 41.7) \cell +\pard\intbl\qc\fs18 41.3 (25.2, 57.5) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2815 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5699 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7140 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8582 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10642 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10642 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsfae02/tsfae02.rtf b/tests/testthat/_snaps/tsfae02/tsfae02.rtf old mode 100755 new mode 100644 index 038d679c..fcb1f224 --- a/tests/testthat/_snaps/tsfae02/tsfae02.rtf +++ b/tests/testthat/_snaps/tsfae02/tsfae02.rtf @@ -6,9 +6,9 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2830 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4212 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5594 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7108 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8490 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10530 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6976 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8358 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10661 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE02:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -24,9 +24,9 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2830 \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4212 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5594 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7108 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8490 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10530 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6976 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8358 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10661 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -42,16 +42,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } @@ -60,14 +60,14 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -78,16 +78,16 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 106 (84.1%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\pard\intbl\qc\fs18 40.3 (26.6, 54.0) \cell -\pard\intbl\qc\fs18 19.4 (3.3, 35.5) \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 96 (81.4%) \cell +\pard\intbl\qc\fs18 38 (59.4%) \cell +\pard\intbl\qc\fs18 15.3 (-0.7, 31.2) \cell +\pard\intbl\qc\fs18 30.8 (16.3, 45.4) \cell \row } @@ -96,9 +96,9 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -114,16 +114,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 56 (44.4%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 31.2 (13.8, 48.5) \cell -\pard\intbl\qc\fs18 10.2 (-5.4, 25.8) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 20.1 (5.3, 34.9) \cell +\pard\intbl\qc\fs18 27.9 (11.4, 44.4) \cell \row } @@ -132,16 +132,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 27.6 (12.4, 42.7) \cell -\pard\intbl\qc\fs18 9.0 (-2.9, 20.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 28 (23.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 16.1 (4.5, 27.7) \cell +\pard\intbl\qc\fs18 19.2 (5.9, 32.6) \cell \row } @@ -150,16 +150,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 12.5 (-1.2, 26.1) \cell -\pard\intbl\qc\fs18 0.8 (-9.7, 11.3) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 16.1 (5.2, 27.0) \cell \row } @@ -168,16 +168,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2.7 (-7.5, 12.8) \cell -\pard\intbl\qc\fs18 5.5 (-4.4, 15.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2.8 (-5.4, 10.9) \cell +\pard\intbl\qc\fs18 9.0 (-1.7, 19.8) \cell \row } @@ -186,16 +186,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 11.7 (1.0, 22.4) \cell -\pard\intbl\qc\fs18 2.1 (-4.9, 9.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 5.8 (-3.2, 14.7) \cell +\pard\intbl\qc\fs18 3.2 (-5.9, 12.2) \cell \row } @@ -204,16 +204,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 4.4 (-2.0, 10.8) \cell +\pard\intbl\qc\fs18 8.2 (-0.5, 16.9) \cell \row } @@ -222,16 +222,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } @@ -240,16 +240,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -258,16 +258,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 21.4 (4.3, 38.4) \cell -\pard\intbl\qc\fs18 20.4 (4.9, 35.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -276,16 +276,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 17.7 (4.5, 31.0) \cell -\pard\intbl\qc\fs18 17.9 (6.1, 29.7) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 9.3 (-6.2, 24.9) \cell +\pard\intbl\qc\fs18 24.0 (6.7, 41.4) \cell \row } @@ -294,16 +294,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 15.5 (4.0, 27.0) \cell -\pard\intbl\qc\fs18 11.7 (2.3, 21.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 8.5 (-3.7, 20.6) \cell +\pard\intbl\qc\fs18 24.4 (9.2, 39.5) \cell \row } @@ -312,16 +312,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 11.7 (1.0, 22.4) \cell -\pard\intbl\qc\fs18 6.2 (-2.0, 14.4) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -0.6 (-11.8, 10.7) \cell +\pard\intbl\qc\fs18 9.1 (-4.8, 23.0) \cell \row } @@ -330,16 +330,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 -0.9 (-11.0, 9.1) \cell -\pard\intbl\qc\fs18 1.1 (-8.7, 10.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 7.2 (-2.9, 17.3) \cell +\pard\intbl\qc\fs18 3.6 (-6.5, 13.6) \cell \row } @@ -348,16 +348,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 6.8 (1.1, 12.6) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell \row } @@ -366,16 +366,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1.4 (-5.2, 7.9) \cell +\pard\intbl\qc\fs18 4.7 (-3.8, 13.2) \cell \row } @@ -384,16 +384,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } @@ -402,9 +402,9 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -420,16 +420,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 19.4 (6.6, 32.3) \cell -\pard\intbl\qc\fs18 12.7 (2.3, 23.1) \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 27 (22.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 16.2 (5.2, 27.2) \cell +\pard\intbl\qc\fs18 20.8 (7.8, 33.8) \cell \row } @@ -438,16 +438,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 15.1 (5.5, 24.7) \cell -\pard\intbl\qc\fs18 11.0 (3.8, 18.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 14.1 (3.7, 24.6) \cell \row } @@ -456,16 +456,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6.0 (-3.1, 15.2) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 7.8 (0.5, 15.2) \cell \row } @@ -474,16 +474,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } @@ -492,16 +492,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 -1.2 (-6.9, 4.5) \cell \row } @@ -510,9 +510,9 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -528,16 +528,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 12.1 (-0.2, 24.4) \cell -\pard\intbl\qc\fs18 4.2 (-5.4, 13.8) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 -8.2 (-19.7, 3.3) \cell +\pard\intbl\qc\fs18 6.3 (-8.5, 21.2) \cell \row } @@ -546,16 +546,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell \row } @@ -564,16 +564,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1.4 (-5.2, 7.9) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell \row } @@ -582,16 +582,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 -11.1 (-20.5, -1.6) \cell +\pard\intbl\qc\fs18 -8.2 (-18.9, 2.5) \cell \row } @@ -600,16 +600,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } @@ -618,9 +618,9 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -636,16 +636,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 13.8 (1.9, 25.7) \cell -\pard\intbl\qc\fs18 4.5 (-4.3, 13.3) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 16 (13.6%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 4.1 (-6.0, 14.3) \cell +\pard\intbl\qc\fs18 7.9 (-4.1, 19.8) \cell \row } @@ -654,16 +654,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 13.2 (4.1, 22.3) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 7.4 (-0.1, 14.9) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell \row } @@ -672,16 +672,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0.6 (-7.8, 8.9) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -3.3 (-10.5, 3.9) \cell +\pard\intbl\qc\fs18 -2.3 (-10.3, 5.6) \cell \row } @@ -690,16 +690,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -708,9 +708,9 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -726,16 +726,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 4.3 (-5.3, 14.0) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -9.5 (-18.6, -0.4) \cell +\pard\intbl\qc\fs18 1.2 (-11.2, 13.7) \cell \row } @@ -744,16 +744,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4.0 (-3.1, 11.0) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell \row } @@ -762,16 +762,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 -7.9 (-15.6, -0.2) \cell +\pard\intbl\qc\fs18 -5.5 (-14.4, 3.5) \cell \row } @@ -780,9 +780,9 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -798,16 +798,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 -2.4 (-13.8, 9.0) \cell -\pard\intbl\qc\fs18 -7.8 (-17.2, 1.7) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -0.2 (-7.4, 7.0) \cell +\pard\intbl\qc\fs18 7.1 (-3.2, 17.3) \cell \row } @@ -816,16 +816,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } @@ -834,16 +834,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 -4.7 (-13.5, 4.1) \cell -\pard\intbl\qc\fs18 -8.5 (-15.6, -1.4) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell \row } @@ -852,9 +852,9 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -870,16 +870,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } @@ -888,70 +888,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell \row } @@ -960,16 +906,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -978,9 +924,9 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -996,16 +942,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell \row } @@ -1014,16 +960,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell \row } @@ -1032,9 +978,9 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1050,16 +996,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } @@ -1068,16 +1014,16 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2830 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4212 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5594 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7108 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8490 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10530 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } @@ -1086,9 +1032,9 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2830 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4212 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5594 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7108 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8490 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10530 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6976 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8358 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10661 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -1104,9 +1050,9 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7108 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8490 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae02a/tsfae02a.rtf b/tests/testthat/_snaps/tsfae02a/tsfae02a.rtf old mode 100755 new mode 100644 index 81ee5232..1c37ed95 --- a/tests/testthat/_snaps/tsfae02a/tsfae02a.rtf +++ b/tests/testthat/_snaps/tsfae02a/tsfae02a.rtf @@ -3,12 +3,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2816 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4255 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5569 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7008 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8322 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10512 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6864 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8211 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10456 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE02a:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,12 +21,12 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2816 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4255 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5569 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7008 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8322 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10512 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6864 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8211 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10456 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -39,35 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -75,17 +75,17 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age Group: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 9 \cell \pard\intbl\qc\fs18 13 \cell -\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 12 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -93,12 +93,12 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -111,30 +111,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 8 (100.0%) \cell -\pard\intbl\qc\fs18 5 (100.0%) \cell -\pard\intbl\qc\fs18 13 (100.0%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 71.4 (38.0, 100.0) \cell -\pard\intbl\qc\fs18 71.4 (38.0, 100.0) \cell +\pard\intbl\qc\fs18 4 (100.0%) \cell +\pard\intbl\qc\fs18 8 (88.9%) \cell +\pard\intbl\qc\fs18 12 (92.3%) \cell +\pard\intbl\qc\fs18 8 (66.7%) \cell +\pard\intbl\qc\fs18 33.3 (6.7, 60.0) \cell +\pard\intbl\qc\fs18 22.2 (-11.4, 55.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -147,120 +147,120 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 6 (75.0%) \cell -\pard\intbl\qc\fs18 4 (80.0%) \cell -\pard\intbl\qc\fs18 10 (76.9%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 60.7 (21.1, 100.0) \cell -\pard\intbl\qc\fs18 65.7 (22.1, 100.0) \cell +\pard\intbl\qc\fs18 3 (75.0%) \cell +\pard\intbl\qc\fs18 5 (55.6%) \cell +\pard\intbl\qc\fs18 8 (61.5%) \cell +\pard\intbl\qc\fs18 4 (33.3%) \cell +\pard\intbl\qc\fs18 41.7 (-8.5, 91.8) \cell +\pard\intbl\qc\fs18 22.2 (-19.8, 64.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 3 (60.0%) \cell -\pard\intbl\qc\fs18 7 (53.8%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 35.7 (-7.6, 79.0) \cell -\pard\intbl\qc\fs18 45.7 (-4.4, 95.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 2 (50.0%) \cell +\pard\intbl\qc\fs18 3 (33.3%) \cell +\pard\intbl\qc\fs18 5 (38.5%) \cell +\pard\intbl\qc\fs18 3 (25.0%) \cell +\pard\intbl\qc\fs18 25.0 (-29.8, 79.8) \cell +\pard\intbl\qc\fs18 8.3 (-31.0, 47.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 6 (46.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 4 (44.4%) \cell +\pard\intbl\qc\fs18 5 (38.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 62.5 (29.0, 96.0) \cell -\pard\intbl\qc\fs18 20.0 (-15.1, 55.1) \cell +\pard\intbl\qc\fs18 25.0 (-17.4, 67.4) \cell +\pard\intbl\qc\fs18 44.4 (12.0, 76.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell \pard\intbl\qc\fs18 3 (23.1%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 10.7 (-28.9, 50.4) \cell -\pard\intbl\qc\fs18 5.7 (-37.9, 49.3) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 16.7 (-28.6, 61.9) \cell +\pard\intbl\qc\fs18 13.9 (-17.5, 45.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 2 (15.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 20.0 (-15.1, 55.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell +\pard\intbl\qc\fs18 3 (23.1%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 16.7 (-28.6, 61.9) \cell +\pard\intbl\qc\fs18 13.9 (-17.5, 45.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell \pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 -8.3 (-24.0, 7.3) \cell +\pard\intbl\qc\fs18 2.8 (-23.0, 28.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -273,102 +273,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 5 (55.6%) \cell \pard\intbl\qc\fs18 6 (46.2%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 33.9 (-13.5, 81.3) \cell -\pard\intbl\qc\fs18 -8.6 (-57.0, 39.9) \cell +\pard\intbl\qc\fs18 3 (25.0%) \cell +\pard\intbl\qc\fs18 0.0 (-49.0, 49.0) \cell +\pard\intbl\qc\fs18 30.6 (-10.1, 71.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 5 (38.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 50.0 (15.4, 84.6) \cell -\pard\intbl\qc\fs18 20.0 (-15.1, 55.1) \cell +\pard\intbl\qc\fs18 4 (44.4%) \cell +\pard\intbl\qc\fs18 4 (30.8%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 -8.3 (-24.0, 7.3) \cell +\pard\intbl\qc\fs18 36.1 (0.1, 72.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 4 (30.8%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 23.2 (-19.2, 65.6) \cell -\pard\intbl\qc\fs18 5.7 (-37.9, 49.3) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (33.3%) \cell +\pard\intbl\qc\fs18 3 (23.1%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 -8.3 (-24.0, 7.3) \cell +\pard\intbl\qc\fs18 25.0 (-9.5, 59.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell \pard\intbl\qc\fs18 1 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 11.1 (-9.4, 31.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 -14.3 (-40.2, 11.6) \cell -\pard\intbl\qc\fs18 -14.3 (-40.2, 11.6) \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 16.7 (-28.6, 61.9) \cell +\pard\intbl\qc\fs18 -8.3 (-24.0, 7.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -381,66 +381,84 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell \pard\intbl\qc\fs18 2 (15.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25.0 (-5.0, 55.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 4 (33.3%) \cell +\pard\intbl\qc\fs18 -33.3 (-60.0, -6.7) \cell +\pard\intbl\qc\fs18 -11.1 (-49.2, 27.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell \pard\intbl\qc\fs18 2 (15.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25.0 (-5.0, 55.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 -8.3 (-24.0, 7.3) \cell +\pard\intbl\qc\fs18 13.9 (-17.5, 45.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell \pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 -8.3 (-24.0, 7.3) \cell +\pard\intbl\qc\fs18 2.8 (-23.0, 28.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (25.0%) \cell +\pard\intbl\qc\fs18 -25.0 (-49.5, -0.5) \cell +\pard\intbl\qc\fs18 -25.0 (-49.5, -0.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -453,48 +471,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell +\pard\intbl\qc\fs18 2 (15.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 22.2 (-4.9, 49.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell \pard\intbl\qc\fs18 1 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 20.0 (-15.1, 55.1) \cell +\pard\intbl\qc\fs18 11.1 (-9.4, 31.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell \pard\intbl\qc\fs18 1 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 20.0 (-15.1, 55.1) \cell +\pard\intbl\qc\fs18 11.1 (-9.4, 31.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -507,66 +543,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell +\pard\intbl\qc\fs18 2 (15.4%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 -8.3 (-24.0, 7.3) \cell +\pard\intbl\qc\fs18 13.9 (-17.5, 45.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell +\pard\intbl\qc\fs18 2 (15.4%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 -8.3 (-24.0, 7.3) \cell +\pard\intbl\qc\fs18 13.9 (-17.5, 45.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell \pard\intbl\qc\fs18 1 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 11.1 (-9.4, 31.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -579,48 +615,84 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell +\pard\intbl\qc\fs18 2 (15.4%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 -8.3 (-24.0, 7.3) \cell +\pard\intbl\qc\fs18 13.9 (-17.5, 45.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\pard\intbl\qc\fs18 -8.3 (-24.0, 7.3) \cell +\pard\intbl\qc\fs18 2.8 (-23.0, 28.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell \pard\intbl\qc\fs18 1 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 11.1 (-9.4, 31.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell \pard\intbl\qc\fs18 1 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 11.1 (-9.4, 31.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -633,48 +705,48 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell \pard\intbl\qc\fs18 1 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 11.1 (-9.4, 31.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell \pard\intbl\qc\fs18 1 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 11.1 (-9.4, 31.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -687,71 +759,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell +\pard\intbl\qc\fs18 25.0 (-17.4, 67.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell +\pard\intbl\qc\fs18 25.0 (-17.4, 67.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age Group: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 33 \cell \pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 16 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -759,12 +813,12 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -777,30 +831,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 14 (87.5%) \cell -\pard\intbl\qc\fs18 15 (88.2%) \cell -\pard\intbl\qc\fs18 29 (87.9%) \cell -\pard\intbl\qc\fs18 10 (52.6%) \cell -\pard\intbl\qc\fs18 34.9 (7.2, 62.6) \cell -\pard\intbl\qc\fs18 35.6 (8.4, 62.8) \cell +\pard\intbl\qc\fs18 16 (84.2%) \cell +\pard\intbl\qc\fs18 13 (86.7%) \cell +\pard\intbl\qc\fs18 29 (85.3%) \cell +\pard\intbl\qc\fs18 7 (43.8%) \cell +\pard\intbl\qc\fs18 40.5 (11.1, 69.8) \cell +\pard\intbl\qc\fs18 42.9 (13.1, 72.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -813,156 +867,138 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 6 (37.5%) \cell -\pard\intbl\qc\fs18 7 (41.2%) \cell -\pard\intbl\qc\fs18 13 (39.4%) \cell -\pard\intbl\qc\fs18 6 (31.6%) \cell -\pard\intbl\qc\fs18 5.9 (-25.7, 37.5) \cell -\pard\intbl\qc\fs18 9.6 (-21.8, 41.0) \cell +\pard\intbl\qc\fs18 5 (26.3%) \cell +\pard\intbl\qc\fs18 7 (46.7%) \cell +\pard\intbl\qc\fs18 12 (35.3%) \cell +\pard\intbl\qc\fs18 4 (25.0%) \cell +\pard\intbl\qc\fs18 1.3 (-27.7, 30.3) \cell +\pard\intbl\qc\fs18 21.7 (-11.3, 54.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 5 (31.2%) \cell -\pard\intbl\qc\fs18 5 (29.4%) \cell -\pard\intbl\qc\fs18 10 (30.3%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 4 (21.1%) \cell +\pard\intbl\qc\fs18 6 (40.0%) \cell +\pard\intbl\qc\fs18 10 (29.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 31.2 (8.5, 54.0) \cell -\pard\intbl\qc\fs18 29.4 (7.8, 51.1) \cell +\pard\intbl\qc\fs18 21.1 (2.7, 39.4) \cell +\pard\intbl\qc\fs18 40.0 (15.2, 64.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 3 (17.6%) \cell -\pard\intbl\qc\fs18 5 (15.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell \pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 2.0 (-19.3, 23.3) \cell -\pard\intbl\qc\fs18 7.1 (-15.7, 29.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell +\pard\intbl\qc\fs18 3 (20.0%) \cell +\pard\intbl\qc\fs18 5 (14.7%) \cell \pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-3.7, 28.7) \cell -\pard\intbl\qc\fs18 11.8 (-3.6, 27.1) \cell +\pard\intbl\qc\fs18 -2.0 (-23.3, 19.3) \cell +\pard\intbl\qc\fs18 7.5 (-18.4, 33.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 11.8 (-3.6, 27.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 -1.0 (-16.5, 14.6) \cell +\pard\intbl\qc\fs18 0.4 (-16.9, 17.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 3 (15.8%) \cell -\pard\intbl\qc\fs18 -9.5 (-29.8, 10.7) \cell -\pard\intbl\qc\fs18 -9.9 (-29.8, 9.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5.3 (-4.8, 15.3) \cell +\pard\intbl\qc\fs18 6.7 (-6.0, 19.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 -1.0 (-16.5, 14.6) \cell +\pard\intbl\qc\fs18 0.4 (-16.9, 17.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell +\pard\intbl\qc\fs18 5.3 (-4.8, 15.3) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -975,120 +1011,138 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 7 (43.8%) \cell -\pard\intbl\qc\fs18 5 (29.4%) \cell -\pard\intbl\qc\fs18 12 (36.4%) \cell +\pard\intbl\qc\fs18 6 (31.6%) \cell +\pard\intbl\qc\fs18 5 (33.3%) \cell +\pard\intbl\qc\fs18 11 (32.4%) \cell +\pard\intbl\qc\fs18 3 (18.8%) \cell +\pard\intbl\qc\fs18 12.8 (-15.5, 41.2) \cell +\pard\intbl\qc\fs18 14.6 (-16.0, 45.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell \pard\intbl\qc\fs18 4 (21.1%) \cell -\pard\intbl\qc\fs18 22.7 (-7.7, 53.1) \cell -\pard\intbl\qc\fs18 8.4 (-20.0, 36.7) \cell +\pard\intbl\qc\fs18 5 (33.3%) \cell +\pard\intbl\qc\fs18 9 (26.5%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 14.8 (-7.0, 36.6) \cell +\pard\intbl\qc\fs18 27.1 (0.4, 53.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 6 (37.5%) \cell -\pard\intbl\qc\fs18 3 (17.6%) \cell -\pard\intbl\qc\fs18 9 (27.3%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 32.2 (6.5, 58.0) \cell -\pard\intbl\qc\fs18 12.4 (-8.3, 33.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 3 (8.8%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 4.3 (-13.9, 22.5) \cell +\pard\intbl\qc\fs18 0.4 (-16.9, 17.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 7.2 (-11.8, 26.3) \cell -\pard\intbl\qc\fs18 6.5 (-11.8, 24.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 3 (8.8%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 4.3 (-13.9, 22.5) \cell +\pard\intbl\qc\fs18 0.4 (-16.9, 17.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell \pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 7.2 (-11.8, 26.3) \cell -\pard\intbl\qc\fs18 0.6 (-14.4, 15.6) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 -1.0 (-16.5, 14.6) \cell +\pard\intbl\qc\fs18 0.4 (-16.9, 17.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 -4.3 (-22.5, 13.9) \cell -\pard\intbl\qc\fs18 1.2 (-19.4, 21.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5.3 (-4.8, 15.3) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 6.7 (-6.0, 19.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1101,66 +1155,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 3 (18.8%) \cell -\pard\intbl\qc\fs18 4 (23.5%) \cell -\pard\intbl\qc\fs18 7 (21.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 4 (26.7%) \cell +\pard\intbl\qc\fs18 7 (20.6%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 9.5 (-10.7, 29.8) \cell +\pard\intbl\qc\fs18 20.4 (-4.9, 45.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell \pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 8.2 (-15.4, 31.8) \cell -\pard\intbl\qc\fs18 13.0 (-11.4, 37.4) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 3 (8.8%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 4.3 (-13.9, 22.5) \cell +\pard\intbl\qc\fs18 0.4 (-16.9, 17.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 4 (23.5%) \cell -\pard\intbl\qc\fs18 6 (18.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (13.3%) \cell +\pard\intbl\qc\fs18 3 (8.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-3.7, 28.7) \cell -\pard\intbl\qc\fs18 23.5 (3.4, 43.7) \cell +\pard\intbl\qc\fs18 5.3 (-4.8, 15.3) \cell +\pard\intbl\qc\fs18 13.3 (-3.9, 30.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 -4.3 (-22.5, 13.9) \cell -\pard\intbl\qc\fs18 -4.6 (-22.4, 13.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5.3 (-4.8, 15.3) \cell +\pard\intbl\qc\fs18 6.7 (-6.0, 19.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5.3 (-4.8, 15.3) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1173,84 +1263,138 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 7.2 (-11.8, 26.3) \cell -\pard\intbl\qc\fs18 6.5 (-11.8, 24.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 5 (26.3%) \cell +\pard\intbl\qc\fs18 2 (13.3%) \cell +\pard\intbl\qc\fs18 7 (20.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26.3 (6.5, 46.1) \cell +\pard\intbl\qc\fs18 13.3 (-3.9, 30.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 5 (26.3%) \cell +\pard\intbl\qc\fs18 2 (13.3%) \cell +\pard\intbl\qc\fs18 7 (20.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\pard\intbl\qc\fs18 26.3 (6.5, 46.1) \cell +\pard\intbl\qc\fs18 13.3 (-3.9, 30.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5.3 (-4.8, 15.3) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 3 (8.8%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 4.3 (-13.9, 22.5) \cell +\pard\intbl\qc\fs18 0.4 (-16.9, 17.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 3 (8.8%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 4.3 (-13.9, 22.5) \cell +\pard\intbl\qc\fs18 0.4 (-16.9, 17.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell \pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\pard\intbl\qc\fs18 0.6 (-14.4, 15.6) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5.3 (-4.8, 15.3) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1263,48 +1407,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\pard\intbl\qc\fs18 2 (13.3%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 -6.3 (-18.1, 5.6) \cell +\pard\intbl\qc\fs18 7.1 (-13.8, 28.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 -6.3 (-18.1, 5.6) \cell +\pard\intbl\qc\fs18 0.4 (-16.9, 17.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 6.7 (-6.0, 19.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1317,66 +1479,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 7.2 (-11.8, 26.3) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell +\pard\intbl\qc\fs18 2 (13.3%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 -6.3 (-18.1, 5.6) \cell +\pard\intbl\qc\fs18 7.1 (-13.8, 28.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 1.0 (-14.6, 16.5) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 -6.3 (-18.1, 5.6) \cell +\pard\intbl\qc\fs18 0.4 (-16.9, 17.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 6.7 (-6.0, 19.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1389,48 +1551,48 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\pard\intbl\qc\fs18 6.7 (-6.0, 19.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\pard\intbl\qc\fs18 6.7 (-6.0, 19.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1443,53 +1605,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell +\pard\intbl\qc\fs18 5.3 (-4.8, 15.3) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell +\pard\intbl\qc\fs18 5.3 (-4.8, 15.3) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age Group: \u8805?75 years \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 80 \cell -\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 71 \cell +\pard\intbl\qc\fs18 36 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -1497,12 +1659,12 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1515,30 +1677,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 29 (100.0%) \cell -\pard\intbl\qc\fs18 35 (68.6%) \cell -\pard\intbl\qc\fs18 64 (80.0%) \cell -\pard\intbl\qc\fs18 21 (63.6%) \cell -\pard\intbl\qc\fs18 36.4 (20.0, 52.8) \cell -\pard\intbl\qc\fs18 5.0 (-15.8, 25.8) \cell +\pard\intbl\qc\fs18 30 (68.2%) \cell +\pard\intbl\qc\fs18 25 (92.6%) \cell +\pard\intbl\qc\fs18 55 (77.5%) \cell +\pard\intbl\qc\fs18 23 (63.9%) \cell +\pard\intbl\qc\fs18 4.3 (-16.6, 25.2) \cell +\pard\intbl\qc\fs18 28.7 (10.2, 47.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1551,138 +1713,138 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 18 (62.1%) \cell -\pard\intbl\qc\fs18 20 (39.2%) \cell -\pard\intbl\qc\fs18 38 (47.5%) \cell -\pard\intbl\qc\fs18 9 (27.3%) \cell -\pard\intbl\qc\fs18 34.8 (11.5, 58.1) \cell -\pard\intbl\qc\fs18 11.9 (-8.3, 32.2) \cell +\pard\intbl\qc\fs18 16 (36.4%) \cell +\pard\intbl\qc\fs18 15 (55.6%) \cell +\pard\intbl\qc\fs18 31 (43.7%) \cell +\pard\intbl\qc\fs18 10 (27.8%) \cell +\pard\intbl\qc\fs18 8.6 (-11.8, 29.0) \cell +\pard\intbl\qc\fs18 27.8 (4.0, 51.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 10 (34.5%) \cell -\pard\intbl\qc\fs18 10 (19.6%) \cell -\pard\intbl\qc\fs18 20 (25.0%) \cell -\pard\intbl\qc\fs18 5 (15.2%) \cell -\pard\intbl\qc\fs18 19.3 (-1.9, 40.5) \cell -\pard\intbl\qc\fs18 4.5 (-11.9, 20.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 9 (20.5%) \cell +\pard\intbl\qc\fs18 9 (33.3%) \cell +\pard\intbl\qc\fs18 18 (25.4%) \cell +\pard\intbl\qc\fs18 5 (13.9%) \cell +\pard\intbl\qc\fs18 6.6 (-9.9, 23.0) \cell +\pard\intbl\qc\fs18 19.4 (-1.6, 40.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 7 (24.1%) \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell -\pard\intbl\qc\fs18 12 (15.0%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\pard\intbl\qc\fs18 12.0 (-7.1, 31.2) \cell -\pard\intbl\qc\fs18 -2.3 (-16.1, 11.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 6 (13.6%) \cell +\pard\intbl\qc\fs18 7 (25.9%) \cell +\pard\intbl\qc\fs18 13 (18.3%) \cell +\pard\intbl\qc\fs18 6 (16.7%) \cell +\pard\intbl\qc\fs18 -3.0 (-18.9, 12.8) \cell +\pard\intbl\qc\fs18 9.3 (-11.3, 29.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\pard\intbl\qc\fs18 7 (13.7%) \cell -\pard\intbl\qc\fs18 11 (13.8%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 10.8 (-3.1, 24.6) \cell -\pard\intbl\qc\fs18 10.7 (-0.4, 21.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 6 (13.6%) \cell +\pard\intbl\qc\fs18 4 (14.8%) \cell +\pard\intbl\qc\fs18 10 (14.1%) \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell +\pard\intbl\qc\fs18 8.1 (-4.5, 20.7) \cell +\pard\intbl\qc\fs18 9.3 (-6.1, 24.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 8 (10.0%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 14.2 (-0.7, 29.2) \cell -\pard\intbl\qc\fs18 2.9 (-5.9, 11.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 6 (8.5%) \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell +\pard\intbl\qc\fs18 1.3 (-9.3, 11.8) \cell +\pard\intbl\qc\fs18 5.6 (-8.5, 19.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 7 (8.8%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 1.3 (-13.5, 16.1) \cell -\pard\intbl\qc\fs18 -1.2 (-13.5, 11.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 -0.5 (-7.4, 6.4) \cell +\pard\intbl\qc\fs18 8.3 (-4.7, 21.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\pard\intbl\qc\fs18 6.8 (-0.6, 14.3) \cell +\pard\intbl\qc\fs18 3.7 (-3.4, 10.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1695,156 +1857,156 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 11 (37.9%) \cell -\pard\intbl\qc\fs18 20 (39.2%) \cell -\pard\intbl\qc\fs18 31 (38.8%) \cell -\pard\intbl\qc\fs18 6 (18.2%) \cell -\pard\intbl\qc\fs18 19.7 (-2.3, 41.8) \cell -\pard\intbl\qc\fs18 21.0 (2.3, 39.8) \cell +\pard\intbl\qc\fs18 17 (38.6%) \cell +\pard\intbl\qc\fs18 11 (40.7%) \cell +\pard\intbl\qc\fs18 28 (39.4%) \cell +\pard\intbl\qc\fs18 3 (8.3%) \cell +\pard\intbl\qc\fs18 30.3 (13.3, 47.3) \cell +\pard\intbl\qc\fs18 32.4 (11.8, 53.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\pard\intbl\qc\fs18 10 (19.6%) \cell -\pard\intbl\qc\fs18 14 (17.5%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 4.7 (-11.2, 20.6) \cell -\pard\intbl\qc\fs18 10.5 (-4.1, 25.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 9 (20.5%) \cell +\pard\intbl\qc\fs18 4 (14.8%) \cell +\pard\intbl\qc\fs18 13 (18.3%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 17.7 (4.6, 30.7) \cell +\pard\intbl\qc\fs18 12.0 (-2.4, 26.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 7 (13.7%) \cell -\pard\intbl\qc\fs18 10 (12.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 7 (15.9%) \cell +\pard\intbl\qc\fs18 4 (14.8%) \cell +\pard\intbl\qc\fs18 11 (15.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10.3 (-0.7, 21.4) \cell -\pard\intbl\qc\fs18 13.7 (4.3, 23.2) \cell +\pard\intbl\qc\fs18 15.9 (5.1, 26.7) \cell +\pard\intbl\qc\fs18 14.8 (1.4, 28.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 6 (11.8%) \cell -\pard\intbl\qc\fs18 9 (11.2%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 4.3 (-9.5, 18.0) \cell -\pard\intbl\qc\fs18 5.7 (-6.3, 17.7) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell +\pard\intbl\qc\fs18 4 (14.8%) \cell +\pard\intbl\qc\fs18 7 (9.9%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 4.0 (-5.1, 13.2) \cell +\pard\intbl\qc\fs18 12.0 (-2.4, 26.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 8 (10.0%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 10.8 (-3.1, 24.6) \cell -\pard\intbl\qc\fs18 4.8 (-4.6, 14.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 6 (8.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.8 (-0.6, 14.3) \cell +\pard\intbl\qc\fs18 11.1 (-0.7, 23.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 7 (8.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10.3 (-0.7, 21.4) \cell -\pard\intbl\qc\fs18 7.8 (0.5, 15.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 5 (11.4%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 6 (8.5%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 8.6 (-2.2, 19.4) \cell +\pard\intbl\qc\fs18 0.9 (-8.0, 9.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\pard\intbl\qc\fs18 2.3 (-2.1, 6.7) \cell +\pard\intbl\qc\fs18 7.4 (-2.5, 17.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0.4 (-8.4, 9.3) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 -0.5 (-7.4, 6.4) \cell +\pard\intbl\qc\fs18 0.9 (-8.0, 9.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1857,102 +2019,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 9 (31.0%) \cell -\pard\intbl\qc\fs18 9 (17.6%) \cell -\pard\intbl\qc\fs18 18 (22.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 28.0 (10.2, 45.8) \cell -\pard\intbl\qc\fs18 14.6 (2.6, 26.6) \cell +\pard\intbl\qc\fs18 9 (20.5%) \cell +\pard\intbl\qc\fs18 9 (33.3%) \cell +\pard\intbl\qc\fs18 18 (25.4%) \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell +\pard\intbl\qc\fs18 14.9 (0.8, 29.0) \cell +\pard\intbl\qc\fs18 27.8 (8.5, 47.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 9 (11.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 4 (9.1%) \cell +\pard\intbl\qc\fs18 5 (18.5%) \cell +\pard\intbl\qc\fs18 9 (12.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 17.2 (3.5, 31.0) \cell -\pard\intbl\qc\fs18 7.8 (0.5, 15.2) \cell +\pard\intbl\qc\fs18 9.1 (0.6, 17.6) \cell +\pard\intbl\qc\fs18 18.5 (3.9, 33.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 5 (6.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (9.1%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 5 (7.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10.3 (-0.7, 21.4) \cell -\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\pard\intbl\qc\fs18 9.1 (0.6, 17.6) \cell +\pard\intbl\qc\fs18 3.7 (-3.4, 10.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell +\pard\intbl\qc\fs18 2.3 (-2.1, 6.7) \cell +\pard\intbl\qc\fs18 11.1 (-0.7, 23.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0.4 (-8.4, 9.3) \cell -\pard\intbl\qc\fs18 0.9 (-7.0, 8.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell +\pard\intbl\qc\fs18 -1.0 (-10.7, 8.7) \cell +\pard\intbl\qc\fs18 -1.9 (-12.2, 8.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1965,84 +2127,84 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 9 (31.0%) \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell -\pard\intbl\qc\fs18 14 (17.5%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 21.9 (2.5, 41.4) \cell -\pard\intbl\qc\fs18 0.7 (-12.0, 13.5) \cell +\pard\intbl\qc\fs18 5 (11.4%) \cell +\pard\intbl\qc\fs18 7 (25.9%) \cell +\pard\intbl\qc\fs18 12 (16.9%) \cell +\pard\intbl\qc\fs18 4 (11.1%) \cell +\pard\intbl\qc\fs18 0.3 (-13.7, 14.2) \cell +\pard\intbl\qc\fs18 14.8 (-4.6, 34.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 6 (20.7%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 8 (10.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell +\pard\intbl\qc\fs18 5 (18.5%) \cell +\pard\intbl\qc\fs18 8 (11.3%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 20.7 (5.9, 35.4) \cell -\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\pard\intbl\qc\fs18 6.8 (-0.6, 14.3) \cell +\pard\intbl\qc\fs18 18.5 (3.9, 33.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 1.3 (-13.5, 16.1) \cell -\pard\intbl\qc\fs18 -7.1 (-17.7, 3.4) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 4 (11.1%) \cell +\pard\intbl\qc\fs18 -8.8 (-20.0, 2.3) \cell +\pard\intbl\qc\fs18 -3.7 (-18.0, 10.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 -0.5 (-7.4, 6.4) \cell +\pard\intbl\qc\fs18 0.9 (-8.0, 9.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2055,102 +2217,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 7 (24.1%) \cell -\pard\intbl\qc\fs18 6 (11.8%) \cell -\pard\intbl\qc\fs18 13 (16.2%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 15.0 (-3.4, 33.5) \cell -\pard\intbl\qc\fs18 2.7 (-10.5, 15.9) \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell +\pard\intbl\qc\fs18 6 (22.2%) \cell +\pard\intbl\qc\fs18 9 (12.7%) \cell +\pard\intbl\qc\fs18 6 (16.7%) \cell +\pard\intbl\qc\fs18 -9.8 (-24.1, 4.4) \cell +\pard\intbl\qc\fs18 5.6 (-14.3, 25.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 0.8 (-11.5, 13.1) \cell -\pard\intbl\qc\fs18 -2.1 (-11.9, 7.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 5 (7.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.5 (-1.6, 10.7) \cell +\pard\intbl\qc\fs18 11.1 (-0.7, 23.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10.3 (-0.7, 21.4) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 1.8 (-6.4, 9.9) \cell +\pard\intbl\qc\fs18 4.6 (-6.6, 15.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10.3 (-0.7, 21.4) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 5 (13.9%) \cell +\pard\intbl\qc\fs18 -13.9 (-25.2, -2.6) \cell +\pard\intbl\qc\fs18 -6.5 (-21.5, 8.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 0.9 (-7.0, 8.8) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 -2.8 (-8.1, 2.6) \cell +\pard\intbl\qc\fs18 -2.8 (-8.1, 2.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2163,66 +2325,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 6 (7.5%) \cell -\pard\intbl\qc\fs18 7 (21.2%) \cell -\pard\intbl\qc\fs18 -7.4 (-26.2, 11.3) \cell -\pard\intbl\qc\fs18 -17.3 (-32.2, -2.4) \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 5 (7.0%) \cell +\pard\intbl\qc\fs18 7 (19.4%) \cell +\pard\intbl\qc\fs18 -14.9 (-29.2, -0.6) \cell +\pard\intbl\qc\fs18 -8.3 (-25.9, 9.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 5 (6.2%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 4.3 (-9.5, 18.0) \cell -\pard\intbl\qc\fs18 -2.1 (-11.9, 7.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell +\pard\intbl\qc\fs18 -3.3 (-12.0, 5.4) \cell +\pard\intbl\qc\fs18 5.6 (-8.5, 19.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 5 (15.2%) \cell -\pard\intbl\qc\fs18 -11.7 (-25.6, 2.2) \cell -\pard\intbl\qc\fs18 -15.2 (-27.4, -2.9) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 5 (13.9%) \cell +\pard\intbl\qc\fs18 -11.6 (-23.7, 0.5) \cell +\pard\intbl\qc\fs18 -13.9 (-25.2, -2.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2235,66 +2397,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 5 (6.2%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 -2.6 (-13.1, 7.9) \cell -\pard\intbl\qc\fs18 1.8 (-9.2, 12.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 5 (7.0%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 4.0 (-5.1, 13.2) \cell +\pard\intbl\qc\fs18 4.6 (-6.6, 15.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 5 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 7.8 (0.5, 15.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 1.8 (-6.4, 9.9) \cell +\pard\intbl\qc\fs18 0.9 (-8.0, 9.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 -6.1 (-14.2, 2.1) \cell -\pard\intbl\qc\fs18 -6.1 (-14.2, 2.1) \cell +\pard\intbl\qc\fs18 2.3 (-2.1, 6.7) \cell +\pard\intbl\qc\fs18 7.4 (-2.5, 17.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2307,66 +2469,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 3.9 (-7.1, 14.8) \cell -\pard\intbl\qc\fs18 0.9 (-7.0, 8.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 5 (7.0%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 4.0 (-5.1, 13.2) \cell +\pard\intbl\qc\fs18 4.6 (-6.6, 15.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 3.9 (-7.1, 14.8) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 5 (7.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.8 (-0.6, 14.3) \cell +\pard\intbl\qc\fs18 7.4 (-2.5, 17.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 -2.8 (-8.1, 2.6) \cell +\pard\intbl\qc\fs18 -2.8 (-8.1, 2.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2379,48 +2541,48 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.5 (-1.6, 10.7) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\pard\intbl\qc\fs18 4.5 (-1.6, 10.7) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2433,48 +2595,48 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 -2.8 (-8.1, 2.6) \cell +\pard\intbl\qc\fs18 0.9 (-8.0, 9.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2816 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4255 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5569 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7008 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8322 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10512 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\pard\intbl\qc\fs18 -2.8 (-8.1, 2.6) \cell +\pard\intbl\qc\fs18 0.9 (-8.0, 9.8) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2816 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4255 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5569 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7008 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8322 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10512 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6864 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8211 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10456 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2487,12 +2649,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2816 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4255 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5569 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7008 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8322 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10512 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae03a/tsfae03a.rtf b/tests/testthat/_snaps/tsfae03a/tsfae03a.rtf old mode 100755 new mode 100644 index 07541908..74ecba07 --- a/tests/testthat/_snaps/tsfae03a/tsfae03a.rtf +++ b/tests/testthat/_snaps/tsfae03a/tsfae03a.rtf @@ -3,12 +3,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4170 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5517 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6864 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8211 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10456 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5675 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE03a:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,12 +21,12 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4170 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5517 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6864 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8211 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10456 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2838 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5675 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7094 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8513 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10607 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -39,948 +39,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age Group: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 13 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 SAE \cell -\pard\intbl\qc\fs18 7 (87.5%) \cell -\pard\intbl\qc\fs18 4 (80.0%) \cell -\pard\intbl\qc\fs18 11 (84.6%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 58.9 (18.4, 99.5) \cell -\pard\intbl\qc\fs18 51.4 (3.0, 99.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 6 (75.0%) \cell -\pard\intbl\qc\fs18 3 (60.0%) \cell -\pard\intbl\qc\fs18 9 (69.2%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 60.7 (21.1, 100.0) \cell -\pard\intbl\qc\fs18 45.7 (-4.4, 95.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 3 (60.0%) \cell -\pard\intbl\qc\fs18 6 (46.2%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 23.2 (-19.2, 65.6) \cell -\pard\intbl\qc\fs18 45.7 (-4.4, 95.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 5 (38.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 50.0 (15.4, 84.6) \cell -\pard\intbl\qc\fs18 20.0 (-15.1, 55.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 3 (23.1%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 10.7 (-28.9, 50.4) \cell -\pard\intbl\qc\fs18 5.7 (-37.9, 49.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 3 (23.1%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 -3.6 (-48.5, 41.4) \cell -\pard\intbl\qc\fs18 -8.6 (-57.0, 39.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 3 (23.1%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 10.7 (-28.9, 50.4) \cell -\pard\intbl\qc\fs18 5.7 (-37.9, 49.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 2 (15.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 20.0 (-15.1, 55.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 -14.3 (-40.2, 11.6) \cell -\pard\intbl\qc\fs18 -14.3 (-40.2, 11.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age Group: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 SAE \cell -\pard\intbl\qc\fs18 11 (68.8%) \cell -\pard\intbl\qc\fs18 11 (64.7%) \cell -\pard\intbl\qc\fs18 22 (66.7%) \cell -\pard\intbl\qc\fs18 9 (47.4%) \cell -\pard\intbl\qc\fs18 21.4 (-10.6, 53.3) \cell -\pard\intbl\qc\fs18 17.3 (-14.6, 49.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 5 (31.2%) \cell -\pard\intbl\qc\fs18 6 (35.3%) \cell -\pard\intbl\qc\fs18 11 (33.3%) \cell -\pard\intbl\qc\fs18 5 (26.3%) \cell -\pard\intbl\qc\fs18 4.9 (-25.2, 35.1) \cell -\pard\intbl\qc\fs18 9.0 (-21.2, 39.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 3 (18.8%) \cell -\pard\intbl\qc\fs18 3 (17.6%) \cell -\pard\intbl\qc\fs18 6 (18.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 18.8 (-0.4, 37.9) \cell -\pard\intbl\qc\fs18 17.6 (-0.5, 35.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 7.2 (-11.8, 26.3) \cell -\pard\intbl\qc\fs18 6.5 (-11.8, 24.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 11.8 (-3.6, 27.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 3 (15.8%) \cell -\pard\intbl\qc\fs18 -9.5 (-29.8, 10.7) \cell -\pard\intbl\qc\fs18 -15.8 (-32.2, 0.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 6 (37.5%) \cell -\pard\intbl\qc\fs18 4 (23.5%) \cell -\pard\intbl\qc\fs18 10 (30.3%) \cell -\pard\intbl\qc\fs18 3 (15.8%) \cell -\pard\intbl\qc\fs18 21.7 (-7.1, 50.5) \cell -\pard\intbl\qc\fs18 7.7 (-18.2, 33.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 5 (31.2%) \cell -\pard\intbl\qc\fs18 3 (17.6%) \cell -\pard\intbl\qc\fs18 8 (24.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 31.2 (8.5, 54.0) \cell -\pard\intbl\qc\fs18 17.6 (-0.5, 35.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 7.2 (-11.8, 26.3) \cell -\pard\intbl\qc\fs18 0.6 (-14.4, 15.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 11.8 (-3.6, 27.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 -4.3 (-22.5, 13.9) \cell -\pard\intbl\qc\fs18 -4.6 (-22.4, 13.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 7.2 (-11.8, 26.3) \cell -\pard\intbl\qc\fs18 0.6 (-14.4, 15.6) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 1.0 (-14.6, 16.5) \cell -\pard\intbl\qc\fs18 0.6 (-14.4, 15.6) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related AE \cell +\pard\intbl\qc\fs18 48 (71.6%) \cell +\pard\intbl\qc\fs18 45 (88.2%) \cell +\pard\intbl\qc\fs18 93 (78.8%) \cell +\pard\intbl\qc\fs18 34 (53.1%) \cell +\pard\intbl\qc\fs18 18.5 (2.2, 34.8) \cell +\pard\intbl\qc\fs18 35.1 (20.0, 50.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -993,174 +111,156 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 20.1 (5.3, 34.9) \cell +\pard\intbl\qc\fs18 27.9 (11.4, 44.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 28 (23.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 16.1 (4.5, 27.7) \cell +\pard\intbl\qc\fs18 19.2 (5.9, 32.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 1.0 (-14.6, 16.5) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 16.1 (5.2, 27.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2.8 (-5.4, 10.9) \cell +\pard\intbl\qc\fs18 9.0 (-1.7, 19.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 5.8 (-3.2, 14.7) \cell +\pard\intbl\qc\fs18 3.2 (-5.9, 12.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 4.4 (-2.0, 10.8) \cell +\pard\intbl\qc\fs18 8.2 (-0.5, 16.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1173,246 +273,138 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age Group: \u8805?75 years \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 80 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 SAE \cell -\pard\intbl\qc\fs18 25 (86.2%) \cell -\pard\intbl\qc\fs18 28 (54.9%) \cell -\pard\intbl\qc\fs18 53 (66.2%) \cell -\pard\intbl\qc\fs18 16 (48.5%) \cell -\pard\intbl\qc\fs18 37.7 (16.5, 58.9) \cell -\pard\intbl\qc\fs18 6.4 (-15.4, 28.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 15 (51.7%) \cell -\pard\intbl\qc\fs18 15 (29.4%) \cell -\pard\intbl\qc\fs18 30 (37.5%) \cell -\pard\intbl\qc\fs18 7 (21.2%) \cell -\pard\intbl\qc\fs18 30.5 (7.6, 53.4) \cell -\pard\intbl\qc\fs18 8.2 (-10.5, 26.9) \cell +\pard\intbl\qc\fs18 21 (31.3%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 46 (39.0%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 6.3 (-9.0, 21.7) \cell +\pard\intbl\qc\fs18 24.0 (6.7, 41.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 6 (20.7%) \cell -\pard\intbl\qc\fs18 6 (11.8%) \cell -\pard\intbl\qc\fs18 12 (15.0%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 11.6 (-6.1, 29.3) \cell -\pard\intbl\qc\fs18 2.7 (-10.5, 15.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 30 (25.4%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 7.0 (-5.0, 18.9) \cell +\pard\intbl\qc\fs18 24.4 (9.2, 39.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 7 (24.1%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 10 (12.5%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 15.0 (-3.4, 33.5) \cell -\pard\intbl\qc\fs18 -3.2 (-15.0, 8.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -2.1 (-13.0, 8.9) \cell +\pard\intbl\qc\fs18 9.1 (-4.8, 23.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 6 (7.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 7.3 (-5.2, 19.8) \cell -\pard\intbl\qc\fs18 2.9 (-5.9, 11.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 5.7 (-4.1, 15.5) \cell +\pard\intbl\qc\fs18 3.6 (-6.5, 13.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 5 (6.2%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 -2.2 (-15.7, 11.3) \cell -\pard\intbl\qc\fs18 -3.2 (-15.0, 8.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0.4 (-8.4, 9.3) \cell -\pard\intbl\qc\fs18 2.9 (-5.9, 11.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell \pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1425,156 +417,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 8 (27.6%) \cell -\pard\intbl\qc\fs18 13 (25.5%) \cell -\pard\intbl\qc\fs18 21 (26.2%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\pard\intbl\qc\fs18 15.5 (-4.2, 35.2) \cell -\pard\intbl\qc\fs18 13.4 (-3.0, 29.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell -\pard\intbl\qc\fs18 7 (8.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 9.8 (1.6, 18.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 7 (8.8%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 4.3 (-9.5, 18.0) \cell -\pard\intbl\qc\fs18 1.8 (-9.2, 12.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 6 (7.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 3.9 (-7.1, 14.8) \cell -\pard\intbl\qc\fs18 4.8 (-4.6, 14.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 25 (21.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 17.8 (7.1, 28.4) \cell +\pard\intbl\qc\fs18 18.4 (6.4, 30.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 3.9 (-7.1, 14.8) \cell -\pard\intbl\qc\fs18 0.9 (-7.0, 8.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell \pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0.4 (-8.4, 9.3) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1587,102 +525,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell -\pard\intbl\qc\fs18 9 (11.2%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 10.8 (-3.1, 24.6) \cell -\pard\intbl\qc\fs18 6.8 (-3.3, 16.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -3.5 (-14.1, 7.1) \cell +\pard\intbl\qc\fs18 5.1 (-8.1, 18.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 8.2 (-0.5, 16.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 0.9 (-7.0, 8.8) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 -6.4 (-14.6, 1.8) \cell +\pard\intbl\qc\fs18 -5.5 (-14.4, 3.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1695,102 +633,84 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 8 (10.0%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 14.2 (-0.7, 29.2) \cell -\pard\intbl\qc\fs18 2.9 (-5.9, 11.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 1.1 (-8.3, 10.6) \cell +\pard\intbl\qc\fs18 0.0 (-9.9, 9.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 5.9 (-1.1, 12.9) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -3.3 (-10.5, 3.9) \cell +\pard\intbl\qc\fs18 -2.3 (-10.3, 5.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1803,138 +723,48 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 7 (8.8%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 11.2 (-4.8, 27.2) \cell -\pard\intbl\qc\fs18 -2.1 (-11.9, 7.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10.3 (-0.7, 21.4) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 0.8 (-11.5, 13.1) \cell -\pard\intbl\qc\fs18 -4.1 (-13.1, 4.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 5 (15.2%) \cell -\pard\intbl\qc\fs18 -8.3 (-23.6, 7.1) \cell -\pard\intbl\qc\fs18 -11.2 (-24.6, 2.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 0.8 (-11.5, 13.1) \cell -\pard\intbl\qc\fs18 -2.1 (-11.9, 7.6) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 -9.1 (-18.9, 0.7) \cell -\pard\intbl\qc\fs18 -9.1 (-18.9, 0.7) \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1947,66 +777,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -3.2 (-9.1, 2.7) \cell +\pard\intbl\qc\fs18 -2.7 (-9.2, 3.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell +\pard\intbl\qc\fs18 -1.2 (-6.9, 4.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2019,48 +849,48 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2073,16 +903,16 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell @@ -2091,16 +921,16 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell @@ -2109,12 +939,12 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2127,48 +957,48 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -4.7 (-9.9, 0.5) \cell +\pard\intbl\qc\fs18 -4.7 (-9.9, 0.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4170 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5517 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6864 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8211 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10456 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -4.7 (-9.9, 0.5) \cell +\pard\intbl\qc\fs18 -4.7 (-9.9, 0.5) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4170 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5517 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6864 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8211 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10456 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5675 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10607 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -2181,12 +1011,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae03/tsfae03.rtf b/tests/testthat/_snaps/tsfae03b/tsfae03b.rtf old mode 100755 new mode 100644 similarity index 73% rename from tests/testthat/_snaps/tsfae03/tsfae03.rtf rename to tests/testthat/_snaps/tsfae03b/tsfae03b.rtf index 497b4bc2..4001f407 --- a/tests/testthat/_snaps/tsfae03/tsfae03.rtf +++ b/tests/testthat/_snaps/tsfae03b/tsfae03b.rtf @@ -9,7 +9,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE03:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE03b:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -46,12 +46,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } @@ -64,10 +64,10 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -82,12 +82,12 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 SAE \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 43 (58.9%) \cell -\pard\intbl\qc\fs18 86 (68.3%) \cell -\pard\intbl\qc\fs18 27 (45.8%) \cell -\pard\intbl\qc\fs18 35.4 (18.9, 51.9) \cell -\pard\intbl\qc\fs18 13.1 (-3.9, 30.1) \cell +\pard\intbl\qc\fs18 43 (64.2%) \cell +\pard\intbl\qc\fs18 41 (80.4%) \cell +\pard\intbl\qc\fs18 84 (71.2%) \cell +\pard\intbl\qc\fs18 25 (39.1%) \cell +\pard\intbl\qc\fs18 25.1 (8.5, 41.7) \cell +\pard\intbl\qc\fs18 41.3 (25.2, 57.5) \cell \row } @@ -118,12 +118,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 20 (27.4%) \cell -\pard\intbl\qc\fs18 43 (34.1%) \cell -\pard\intbl\qc\fs18 12 (20.3%) \cell -\pard\intbl\qc\fs18 23.1 (6.2, 39.9) \cell -\pard\intbl\qc\fs18 7.1 (-7.4, 21.6) \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 20 (39.2%) \cell +\pard\intbl\qc\fs18 39 (33.1%) \cell +\pard\intbl\qc\fs18 12 (18.8%) \cell +\pard\intbl\qc\fs18 9.6 (-4.8, 24.0) \cell +\pard\intbl\qc\fs18 20.5 (4.0, 36.9) \cell \row } @@ -135,13 +135,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 10 (13.7%) \cell -\pard\intbl\qc\fs18 22 (17.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 17.6 (5.0, 30.1) \cell -\pard\intbl\qc\fs18 8.6 (-1.1, 18.3) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 2.7 (-6.3, 11.8) \cell +\pard\intbl\qc\fs18 9.4 (-2.2, 21.0) \cell \row } @@ -153,13 +153,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 10.2 (-1.8, 22.2) \cell -\pard\intbl\qc\fs18 1.4 (-7.6, 10.4) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 -3.4 (-12.5, 5.7) \cell +\pard\intbl\qc\fs18 8.3 (-4.4, 20.9) \cell \row } @@ -171,13 +171,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6.0 (-3.1, 15.2) \cell -\pard\intbl\qc\fs18 2.1 (-4.9, 9.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 7.3 (-1.2, 15.8) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell \row } @@ -189,13 +189,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 -3.0 (-11.2, 5.2) \cell -\pard\intbl\qc\fs18 -1.3 (-9.6, 7.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } @@ -207,13 +207,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0.6 (-7.8, 8.9) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell \row } @@ -225,13 +225,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } @@ -262,12 +262,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 19 (35.8%) \cell -\pard\intbl\qc\fs18 22 (30.1%) \cell -\pard\intbl\qc\fs18 41 (32.5%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\pard\intbl\qc\fs18 18.9 (2.8, 35.0) \cell -\pard\intbl\qc\fs18 13.2 (-1.0, 27.4) \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 19 (37.3%) \cell +\pard\intbl\qc\fs18 33 (28.0%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 8.4 (-4.3, 21.1) \cell +\pard\intbl\qc\fs18 24.8 (9.2, 40.3) \cell \row } @@ -279,13 +279,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 10 (13.7%) \cell -\pard\intbl\qc\fs18 19 (15.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 11.9 (0.3, 23.5) \cell -\pard\intbl\qc\fs18 8.6 (-1.1, 18.3) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2.8 (-5.4, 10.9) \cell +\pard\intbl\qc\fs18 14.9 (2.9, 27.0) \cell \row } @@ -297,13 +297,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 13.4 (3.2, 23.6) \cell -\pard\intbl\qc\fs18 9.3 (1.4, 17.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 10.4 (3.1, 17.8) \cell +\pard\intbl\qc\fs18 11.8 (2.9, 20.6) \cell \row } @@ -315,13 +315,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6.0 (-3.1, 15.2) \cell -\pard\intbl\qc\fs18 3.5 (-3.9, 10.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -0.2 (-7.4, 7.0) \cell +\pard\intbl\qc\fs18 3.2 (-5.9, 12.2) \cell \row } @@ -333,13 +333,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 -1.1 (-10.1, 7.8) \cell -\pard\intbl\qc\fs18 -1.3 (-9.6, 7.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2.8 (-4.3, 9.9) \cell +\pard\intbl\qc\fs18 0.8 (-6.0, 7.6) \cell \row } @@ -351,13 +351,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } @@ -369,13 +369,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } @@ -387,13 +387,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -424,12 +424,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 9.8 (-0.4, 20.0) \cell -\pard\intbl\qc\fs18 4.8 (-3.0, 12.6) \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 16.3 (6.7, 26.0) \cell +\pard\intbl\qc\fs18 16.1 (5.2, 27.0) \cell \row } @@ -441,13 +441,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell +\pard\intbl\qc\fs18 9.0 (2.1, 15.8) \cell +\pard\intbl\qc\fs18 9.8 (1.6, 18.0) \cell \row } @@ -459,13 +459,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 2.4 (-3.2, 8.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } @@ -477,13 +477,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell \row } @@ -495,13 +495,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } @@ -531,31 +531,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 9.8 (-0.4, 20.0) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 8.9 (1.0, 16.8) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell \row } @@ -567,13 +549,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 7.8 (0.5, 15.2) \cell \row } @@ -585,13 +567,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } @@ -603,13 +585,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } @@ -639,49 +621,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6.0 (-3.1, 15.2) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 -5.0 (-14.5, 4.6) \cell +\pard\intbl\qc\fs18 2.8 (-9.4, 14.9) \cell \row } @@ -693,13 +639,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 8.2 (-0.5, 16.9) \cell \row } @@ -711,13 +657,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 -2.8 (-12.3, 6.6) \cell -\pard\intbl\qc\fs18 -4.4 (-12.8, 4.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -4.8 (-11.4, 1.8) \cell +\pard\intbl\qc\fs18 -4.3 (-11.3, 2.8) \cell \row } @@ -729,13 +675,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 -1.2 (-6.9, 4.5) \cell \row } @@ -747,13 +693,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -3.2 (-9.9, 3.5) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } @@ -783,13 +729,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -3.3 (-10.5, 3.9) \cell +\pard\intbl\qc\fs18 1.6 (-7.9, 11.1) \cell \row } @@ -801,13 +747,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } @@ -819,13 +765,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -3.2 (-9.1, 2.7) \cell +\pard\intbl\qc\fs18 -2.7 (-9.2, 3.7) \cell \row } @@ -856,12 +802,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } @@ -873,13 +819,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } @@ -891,12 +837,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -927,13 +873,31 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 -1.2 (-6.9, 4.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -945,13 +909,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -982,12 +946,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell \row } @@ -999,13 +963,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell \row } @@ -1035,13 +999,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -1053,13 +1017,13 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } diff --git a/tests/testthat/_snaps/tsfae12/tsfae12.rtf b/tests/testthat/_snaps/tsfae03c/tsfae03c.rtf old mode 100755 new mode 100644 similarity index 63% rename from tests/testthat/_snaps/tsfae12/tsfae12.rtf rename to tests/testthat/_snaps/tsfae03c/tsfae03c.rtf index 130022ee..74080517 --- a/tests/testthat/_snaps/tsfae12/tsfae12.rtf +++ b/tests/testthat/_snaps/tsfae03c/tsfae03c.rtf @@ -8,8 +8,8 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5706 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7132 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8558 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10596 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE12:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10664 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE03c:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -26,7 +26,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5706 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7132 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8558 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10596 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10664 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -44,14 +44,14 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } @@ -62,12 +62,12 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -80,14 +80,14 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 46 (86.8%) \cell -\pard\intbl\qc\fs18 42 (57.5%) \cell -\pard\intbl\qc\fs18 88 (69.8%) \cell -\pard\intbl\qc\fs18 28 (47.5%) \cell -\pard\intbl\qc\fs18 39.3 (23.7, 55.0) \cell -\pard\intbl\qc\fs18 10.1 (-7.0, 27.1) \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 related SAE \cell +\pard\intbl\qc\fs18 39 (58.2%) \cell +\pard\intbl\qc\fs18 39 (76.5%) \cell +\pard\intbl\qc\fs18 78 (66.1%) \cell +\pard\intbl\qc\fs18 22 (34.4%) \cell +\pard\intbl\qc\fs18 23.8 (7.3, 40.4) \cell +\pard\intbl\qc\fs18 42.1 (25.6, 58.6) \cell \row } @@ -98,7 +98,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -116,14 +116,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 24 (45.3%) \cell -\pard\intbl\qc\fs18 21 (28.8%) \cell -\pard\intbl\qc\fs18 45 (35.7%) \cell -\pard\intbl\qc\fs18 12 (20.3%) \cell -\pard\intbl\qc\fs18 24.9 (8.1, 41.8) \cell -\pard\intbl\qc\fs18 8.4 (-6.2, 23.0) \cell +\pard\intbl\qc\fs18 17 (25.4%) \cell +\pard\intbl\qc\fs18 20 (39.2%) \cell +\pard\intbl\qc\fs18 37 (31.4%) \cell +\pard\intbl\qc\fs18 12 (18.8%) \cell +\pard\intbl\qc\fs18 6.6 (-7.5, 20.8) \cell +\pard\intbl\qc\fs18 20.5 (4.0, 36.9) \cell \row } @@ -134,14 +134,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 14 (26.4%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 19.6 (6.1, 33.1) \cell -\pard\intbl\qc\fs18 9.7 (-1.0, 20.3) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 2.7 (-6.3, 11.8) \cell +\pard\intbl\qc\fs18 9.4 (-2.2, 21.0) \cell \row } @@ -152,14 +152,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 6.6 (-5.4, 18.6) \cell -\pard\intbl\qc\fs18 -0.3 (-9.8, 9.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 -4.9 (-13.6, 3.8) \cell +\pard\intbl\qc\fs18 8.3 (-4.4, 20.9) \cell \row } @@ -170,14 +170,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 11.5 (1.8, 21.2) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 5.8 (-2.2, 13.9) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell \row } @@ -188,14 +188,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 1.8 (-6.3, 9.8) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } @@ -206,14 +206,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell \row } @@ -224,14 +224,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } @@ -242,7 +242,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -260,14 +260,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 20 (27.4%) \cell -\pard\intbl\qc\fs18 40 (31.7%) \cell -\pard\intbl\qc\fs18 9 (15.3%) \cell -\pard\intbl\qc\fs18 22.5 (6.5, 38.4) \cell -\pard\intbl\qc\fs18 12.1 (-1.6, 25.9) \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 19 (37.3%) \cell +\pard\intbl\qc\fs18 33 (28.0%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 8.4 (-4.3, 21.1) \cell +\pard\intbl\qc\fs18 24.8 (9.2, 40.3) \cell \row } @@ -278,14 +278,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 10.2 (-1.8, 22.2) \cell -\pard\intbl\qc\fs18 8.3 (-2.1, 18.7) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2.8 (-5.4, 10.9) \cell +\pard\intbl\qc\fs18 14.9 (2.9, 27.0) \cell \row } @@ -296,14 +296,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 17.0 (6.9, 27.1) \cell -\pard\intbl\qc\fs18 8.2 (1.9, 14.5) \cell +\pard\intbl\qc\fs18 10.4 (3.1, 17.8) \cell +\pard\intbl\qc\fs18 11.8 (2.9, 20.6) \cell \row } @@ -314,14 +314,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 11.7 (1.0, 22.4) \cell -\pard\intbl\qc\fs18 3.5 (-3.9, 10.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -0.2 (-7.4, 7.0) \cell +\pard\intbl\qc\fs18 3.2 (-5.9, 12.2) \cell \row } @@ -332,14 +332,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2.8 (-4.3, 9.9) \cell +\pard\intbl\qc\fs18 0.8 (-6.0, 7.6) \cell \row } @@ -350,14 +350,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } @@ -368,14 +368,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } @@ -386,14 +386,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -404,7 +404,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -422,32 +422,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 8.1 (-2.6, 18.8) \cell -\pard\intbl\qc\fs18 3.1 (-5.3, 11.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4279 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell +\pard\intbl\qc\fs18 17.9 (8.7, 27.1) \cell +\pard\intbl\qc\fs18 13.7 (4.3, 23.2) \cell \row } @@ -458,32 +440,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 -0.7 (-6.6, 5.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4279 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\pard\intbl\qc\fs18 9.0 (2.1, 15.8) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell \row } @@ -494,32 +458,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4279 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 9.8 (-0.4, 20.0) \cell -\pard\intbl\qc\fs18 2.1 (-4.9, 9.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } @@ -530,14 +476,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } @@ -548,13 +494,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -566,14 +512,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -584,14 +530,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 -1.8 (-10.5, 6.8) \cell +\pard\intbl\qc\fs18 4.0 (-7.1, 15.0) \cell \row } @@ -602,14 +548,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } @@ -620,14 +566,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 6.2 (-4.0, 16.4) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -3.2 (-9.1, 2.7) \cell +\pard\intbl\qc\fs18 -2.7 (-9.2, 3.7) \cell \row } @@ -638,14 +584,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 11.3 (2.8, 19.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -656,32 +602,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4279 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -3.2 (-9.9, 3.5) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } @@ -692,7 +620,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -710,14 +638,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 2.1 (-4.9, 9.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 7.4 (-0.1, 14.9) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } @@ -728,14 +656,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } @@ -746,14 +674,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } @@ -764,7 +692,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -782,32 +710,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 0.8 (-8.8, 10.3) \cell -\pard\intbl\qc\fs18 -4.0 (-11.5, 3.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4279 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -818,14 +728,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -836,7 +746,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -854,14 +764,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell \row } @@ -872,14 +782,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } @@ -890,14 +800,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } @@ -908,7 +818,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -926,14 +836,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } @@ -944,14 +854,14 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5706 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7132 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8558 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10596 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10664 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } @@ -962,7 +872,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5706 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7132 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8558 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10596 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10664 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -980,7 +890,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5706 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7132 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8558 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10596 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10664 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae03d/tsfae03d.rtf b/tests/testthat/_snaps/tsfae03d/tsfae03d.rtf new file mode 100644 index 00000000..7c8ae431 --- /dev/null +++ b/tests/testthat/_snaps/tsfae03d/tsfae03d.rtf @@ -0,0 +1,814 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4280 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5730 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7179 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8629 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10631 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE03d:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2831 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4280 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5730 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7179 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8629 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10631 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE leading to treatment discontinuation \cell +\pard\intbl\qc\fs18 16 (23.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 34 (28.8%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\pard\intbl\qc\fs18 8.3 (-5.3, 21.8) \cell +\pard\intbl\qc\fs18 19.7 (3.8, 35.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 5.8 (-3.2, 14.7) \cell +\pard\intbl\qc\fs18 11.0 (-0.2, 22.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -0.3 (-8.5, 7.9) \cell +\pard\intbl\qc\fs18 1.6 (-7.9, 11.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 11.8 (2.9, 20.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 1.3 (-6.4, 9.0) \cell +\pard\intbl\qc\fs18 -2.7 (-9.2, 3.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -3.2 (-9.1, 2.7) \cell +\pard\intbl\qc\fs18 -4.7 (-9.9, 0.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8629 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10631 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4280 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5730 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7179 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8629 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10631 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8629 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10631 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae03e/tsfae03e.rtf b/tests/testthat/_snaps/tsfae03e/tsfae03e.rtf new file mode 100644 index 00000000..6ee59607 --- /dev/null +++ b/tests/testthat/_snaps/tsfae03e/tsfae03e.rtf @@ -0,0 +1,1066 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7049 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8446 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10640 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE03e:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2860 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7049 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8446 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10640 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AEs \u8805? Grade 3 \cell +\pard\intbl\qc\fs18 44 (65.7%) \cell +\pard\intbl\qc\fs18 37 (72.5%) \cell +\pard\intbl\qc\fs18 81 (68.6%) \cell +\pard\intbl\qc\fs18 32 (50.0%) \cell +\pard\intbl\qc\fs18 15.7 (-1.0, 32.4) \cell +\pard\intbl\qc\fs18 22.5 (5.2, 39.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 16 (31.4%) \cell +\pard\intbl\qc\fs18 34 (28.8%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\pard\intbl\qc\fs18 11.2 (-2.6, 25.1) \cell +\pard\intbl\qc\fs18 15.7 (0.2, 31.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 14.7 (3.9, 25.5) \cell +\pard\intbl\qc\fs18 11.0 (-0.2, 22.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 10.4 (2.0, 18.7) \cell +\pard\intbl\qc\fs18 8.2 (-0.5, 16.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1.4 (-5.2, 7.9) \cell +\pard\intbl\qc\fs18 8.6 (-1.2, 18.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 1.3 (-6.4, 9.0) \cell +\pard\intbl\qc\fs18 -0.8 (-8.2, 6.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 17 (25.4%) \cell +\pard\intbl\qc\fs18 15 (29.4%) \cell +\pard\intbl\qc\fs18 32 (27.1%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\pard\intbl\qc\fs18 5.1 (-9.3, 19.4) \cell +\pard\intbl\qc\fs18 9.1 (-6.8, 25.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 2.6 (-8.0, 13.1) \cell +\pard\intbl\qc\fs18 10.2 (-2.8, 23.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 -0.5 (-11.1, 10.1) \cell +\pard\intbl\qc\fs18 -3.1 (-13.7, 7.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 1.3 (-6.4, 9.0) \cell +\pard\intbl\qc\fs18 1.2 (-7.1, 9.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 0.8 (-6.0, 7.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11.9 (4.2, 19.7) \cell +\pard\intbl\qc\fs18 13.7 (4.3, 23.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7.5 (1.2, 13.8) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 -3.5 (-13.4, 6.4) \cell +\pard\intbl\qc\fs18 4.7 (-7.8, 17.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -4.8 (-11.4, 1.8) \cell +\pard\intbl\qc\fs18 -0.4 (-9.1, 8.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 1.2 (-7.4, 9.9) \cell +\pard\intbl\qc\fs18 7.5 (-3.7, 18.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell +\pard\intbl\qc\fs18 9.8 (1.6, 18.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -1.7 (-8.3, 4.9) \cell +\pard\intbl\qc\fs18 -0.8 (-8.2, 6.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 -7.9 (-15.6, -0.2) \cell +\pard\intbl\qc\fs18 0.4 (-10.4, 11.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 4.7 (-3.8, 13.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -6.3 (-12.2, -0.3) \cell +\pard\intbl\qc\fs18 -4.3 (-11.3, 2.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8446 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7049 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8446 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10640 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae04/tsfae04.rtf b/tests/testthat/_snaps/tsfae03f/tsfae03f.rtf old mode 100755 new mode 100644 similarity index 67% rename from tests/testthat/_snaps/tsfae04/tsfae04.rtf rename to tests/testthat/_snaps/tsfae03f/tsfae03f.rtf index 92134a66..d6e5fdb1 --- a/tests/testthat/_snaps/tsfae04/tsfae04.rtf +++ b/tests/testthat/_snaps/tsfae03f/tsfae03f.rtf @@ -8,8 +8,8 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5699 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7140 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8582 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10573 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE04:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10710 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE03f:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -26,7 +26,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5699 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7140 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8582 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10573 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10710 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -44,14 +44,14 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } @@ -62,12 +62,12 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -80,14 +80,14 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE leading to discontinuation \cell -\pard\intbl\qc\fs18 21 (39.6%) \cell -\pard\intbl\qc\fs18 15 (20.5%) \cell -\pard\intbl\qc\fs18 36 (28.6%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\pard\intbl\qc\fs18 22.7 (6.4, 39.0) \cell -\pard\intbl\qc\fs18 3.6 (-9.7, 16.9) \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 infusion-related reactions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 24 (47.1%) \cell +\pard\intbl\qc\fs18 49 (41.5%) \cell +\pard\intbl\qc\fs18 18 (28.1%) \cell +\pard\intbl\qc\fs18 9.2 (-6.8, 25.2) \cell +\pard\intbl\qc\fs18 18.9 (1.4, 36.5) \cell \row } @@ -98,7 +98,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -116,14 +116,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 4.3 (-5.3, 14.0) \cell -\pard\intbl\qc\fs18 3.1 (-5.3, 11.6) \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 25 (21.2%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 10.0 (-1.8, 21.9) \cell +\pard\intbl\qc\fs18 14.2 (0.5, 27.8) \cell \row } @@ -134,14 +134,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell +\pard\intbl\qc\fs18 7.5 (1.2, 13.8) \cell +\pard\intbl\qc\fs18 9.8 (1.6, 18.0) \cell \row } @@ -152,14 +152,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -1.7 (-8.3, 4.9) \cell +\pard\intbl\qc\fs18 5.1 (-4.5, 14.8) \cell \row } @@ -170,14 +170,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } @@ -188,14 +188,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -206,13 +206,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell +\pard\intbl\qc\fs18 4.5 (-0.5, 9.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -224,14 +224,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } @@ -242,7 +242,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -260,14 +260,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 4.5 (-6.1, 15.2) \cell -\pard\intbl\qc\fs18 -2.7 (-10.5, 5.2) \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 1.1 (-9.2, 11.3) \cell +\pard\intbl\qc\fs18 6.3 (-6.0, 18.6) \cell \row } @@ -278,14 +278,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -1.7 (-8.3, 4.9) \cell +\pard\intbl\qc\fs18 5.1 (-4.5, 14.8) \cell \row } @@ -296,14 +296,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 0.8 (-6.0, 7.6) \cell \row } @@ -314,14 +314,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } @@ -332,14 +332,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -350,14 +350,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } @@ -368,14 +368,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -386,7 +386,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -404,14 +404,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell +\pard\intbl\qc\fs18 7.5 (1.2, 13.8) \cell +\pard\intbl\qc\fs18 11.8 (2.9, 20.6) \cell \row } @@ -422,14 +422,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 7.8 (0.5, 15.2) \cell \row } @@ -440,14 +440,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell \row } @@ -458,14 +458,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -476,7 +476,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -494,14 +494,32 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -3.3 (-10.5, 3.9) \cell +\pard\intbl\qc\fs18 -0.4 (-9.1, 8.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } @@ -512,14 +530,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell \row } @@ -530,14 +548,32 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } @@ -548,7 +584,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -566,14 +602,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell \row } @@ -584,14 +620,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell \row } @@ -602,14 +638,68 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } @@ -620,7 +710,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -638,14 +728,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } @@ -656,14 +746,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } @@ -674,7 +764,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -692,14 +782,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 -1.2 (-6.9, 4.5) \cell \row } @@ -710,14 +800,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 -1.2 (-6.9, 4.5) \cell \row } @@ -728,7 +818,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -746,14 +836,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } @@ -764,14 +854,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } @@ -782,7 +872,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -800,13 +890,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -818,13 +908,13 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5699 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7140 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8582 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10710 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -836,7 +926,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5699 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7140 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8582 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10573 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10710 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -854,7 +944,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8582 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10710 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae04a/tsfae04a.rtf b/tests/testthat/_snaps/tsfae04a/tsfae04a.rtf old mode 100755 new mode 100644 index e9dc6492..ba80b619 --- a/tests/testthat/_snaps/tsfae04a/tsfae04a.rtf +++ b/tests/testthat/_snaps/tsfae04a/tsfae04a.rtf @@ -3,12 +3,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4142 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5592 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7041 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8353 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10561 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7049 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8313 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10640 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE04a:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,12 +21,12 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2831 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4142 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5592 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7041 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8353 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10561 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2860 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7049 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8313 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10640 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -39,35 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -75,1398 +75,462 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age Group: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 13 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE leading to discontinuation \cell -\pard\intbl\qc\fs18 6 (75.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 (46.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 75.0 (45.0, 100.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (15.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25.0 (-5.0, 55.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (15.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25.0 (-5.0, 55.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (15.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25.0 (-5.0, 55.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age Group: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE leading to discontinuation \cell -\pard\intbl\qc\fs18 7 (43.8%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 9 (27.3%) \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 33.2 (5.3, 61.2) \cell -\pard\intbl\qc\fs18 1.2 (-19.4, 21.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 7.2 (-11.8, 26.3) \cell -\pard\intbl\qc\fs18 0.6 (-14.4, 15.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 3 (18.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 13.5 (-8.1, 35.1) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 1.0 (-14.6, 16.5) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 8.5 (-3.7, 20.6) \cell +\pard\intbl\qc\fs18 24.4 (9.2, 39.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 28 (23.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 16.1 (4.5, 27.7) \cell +\pard\intbl\qc\fs18 19.2 (5.9, 32.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -0.6 (-11.8, 10.7) \cell +\pard\intbl\qc\fs18 9.1 (-4.8, 23.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 16.1 (5.2, 27.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 14.1 (3.7, 24.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 7.2 (-2.9, 17.3) \cell +\pard\intbl\qc\fs18 3.6 (-6.5, 13.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2.8 (-5.4, 10.9) \cell +\pard\intbl\qc\fs18 9.0 (-1.7, 19.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 7.4 (-0.1, 14.9) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 5.8 (-3.2, 14.7) \cell +\pard\intbl\qc\fs18 3.2 (-5.9, 12.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 4.4 (-2.0, 10.8) \cell +\pard\intbl\qc\fs18 8.2 (-0.5, 16.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1.4 (-5.2, 7.9) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age Group: \u8805?75 years \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 80 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE leading to discontinuation \cell -\pard\intbl\qc\fs18 8 (27.6%) \cell -\pard\intbl\qc\fs18 13 (25.5%) \cell -\pard\intbl\qc\fs18 21 (26.2%) \cell -\pard\intbl\qc\fs18 8 (24.2%) \cell -\pard\intbl\qc\fs18 3.3 (-18.5, 25.2) \cell -\pard\intbl\qc\fs18 1.2 (-17.6, 20.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1.4 (-5.2, 7.9) \cell +\pard\intbl\qc\fs18 4.7 (-3.8, 13.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 7 (8.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10.3 (-0.7, 21.4) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell \pard\intbl\qc\fs18 7.8 (0.5, 15.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 5 (9.8%) \cell -\pard\intbl\qc\fs18 6 (7.5%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 -2.6 (-13.1, 7.9) \cell -\pard\intbl\qc\fs18 3.7 (-7.8, 15.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0.4 (-8.4, 9.3) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell \pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 -5.6 (-17.5, 6.2) \cell -\pard\intbl\qc\fs18 -3.2 (-15.0, 8.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 -11.1 (-20.5, -1.6) \cell +\pard\intbl\qc\fs18 -8.2 (-18.9, 2.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 -5.6 (-17.5, 6.2) \cell -\pard\intbl\qc\fs18 -7.1 (-17.7, 3.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0.4 (-8.4, 9.3) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 -6.1 (-14.2, 2.1) \cell -\pard\intbl\qc\fs18 -6.1 (-14.2, 2.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -3.3 (-10.5, 3.9) \cell +\pard\intbl\qc\fs18 -2.3 (-10.3, 5.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4142 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5592 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7041 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8353 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10561 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4256 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5653 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7049 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8313 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10640 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 -7.9 (-15.6, -0.2) \cell +\pard\intbl\qc\fs18 -5.5 (-14.4, 3.5) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4142 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5592 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7041 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8353 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10561 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7049 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8313 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10640 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -1479,12 +543,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4142 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5592 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7041 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8353 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10561 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8313 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10640 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae04b/tsfae04b.rtf b/tests/testthat/_snaps/tsfae04b/tsfae04b.rtf new file mode 100644 index 00000000..b2327788 --- /dev/null +++ b/tests/testthat/_snaps/tsfae04b/tsfae04b.rtf @@ -0,0 +1,508 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4280 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5730 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7179 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8491 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10769 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE04b:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2831 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4280 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5730 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7179 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8491 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10769 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 8.5 (-3.7, 20.6) \cell +\pard\intbl\qc\fs18 24.4 (9.2, 39.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 28 (23.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 16.1 (4.5, 27.7) \cell +\pard\intbl\qc\fs18 19.2 (5.9, 32.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -0.6 (-11.8, 10.7) \cell +\pard\intbl\qc\fs18 9.1 (-4.8, 23.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 16.1 (5.2, 27.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 14.1 (3.7, 24.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 7.2 (-2.9, 17.3) \cell +\pard\intbl\qc\fs18 3.6 (-6.5, 13.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2.8 (-5.4, 10.9) \cell +\pard\intbl\qc\fs18 9.0 (-1.7, 19.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 7.4 (-0.1, 14.9) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 5.8 (-3.2, 14.7) \cell +\pard\intbl\qc\fs18 3.2 (-5.9, 12.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 4.4 (-2.0, 10.8) \cell +\pard\intbl\qc\fs18 8.2 (-0.5, 16.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1.4 (-5.2, 7.9) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1.4 (-5.2, 7.9) \cell +\pard\intbl\qc\fs18 4.7 (-3.8, 13.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 7.8 (0.5, 15.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4280 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5730 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7179 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8491 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10769 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4280 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5730 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7179 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8491 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10769 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4280 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5730 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7179 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8491 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10769 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae04c/tsfae04c.rtf b/tests/testthat/_snaps/tsfae04c/tsfae04c.rtf new file mode 100644 index 00000000..16481476 --- /dev/null +++ b/tests/testthat/_snaps/tsfae04c/tsfae04c.rtf @@ -0,0 +1,832 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2830 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4212 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5594 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6976 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8358 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10661 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE04c:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2830 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4212 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5594 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6976 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8358 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10661 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 20.1 (5.3, 34.9) \cell +\pard\intbl\qc\fs18 27.9 (11.4, 44.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 28 (23.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 16.1 (4.5, 27.7) \cell +\pard\intbl\qc\fs18 19.2 (5.9, 32.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 16.1 (5.2, 27.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2.8 (-5.4, 10.9) \cell +\pard\intbl\qc\fs18 9.0 (-1.7, 19.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 5.8 (-3.2, 14.7) \cell +\pard\intbl\qc\fs18 3.2 (-5.9, 12.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 4.4 (-2.0, 10.8) \cell +\pard\intbl\qc\fs18 8.2 (-0.5, 16.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 9.3 (-6.2, 24.9) \cell +\pard\intbl\qc\fs18 24.0 (6.7, 41.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 8.5 (-3.7, 20.6) \cell +\pard\intbl\qc\fs18 24.4 (9.2, 39.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -0.6 (-11.8, 10.7) \cell +\pard\intbl\qc\fs18 9.1 (-4.8, 23.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 7.2 (-2.9, 17.3) \cell +\pard\intbl\qc\fs18 3.6 (-6.5, 13.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1.4 (-5.2, 7.9) \cell +\pard\intbl\qc\fs18 4.7 (-3.8, 13.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 27 (22.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 16.2 (5.2, 27.2) \cell +\pard\intbl\qc\fs18 20.8 (7.8, 33.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 14.1 (3.7, 24.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 7.8 (0.5, 15.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6.0 (0.3, 11.6) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 -8.2 (-19.7, 3.3) \cell +\pard\intbl\qc\fs18 6.3 (-8.5, 21.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1.4 (-5.2, 7.9) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 -11.1 (-20.5, -1.6) \cell +\pard\intbl\qc\fs18 -8.2 (-18.9, 2.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 16 (13.6%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 4.1 (-6.0, 14.3) \cell +\pard\intbl\qc\fs18 7.9 (-4.1, 19.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 7.4 (-0.1, 14.9) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -3.3 (-10.5, 3.9) \cell +\pard\intbl\qc\fs18 -2.3 (-10.3, 5.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -9.5 (-18.6, -0.4) \cell +\pard\intbl\qc\fs18 1.2 (-11.2, 13.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 6.7 (-2.5, 15.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 -7.9 (-15.6, -0.2) \cell +\pard\intbl\qc\fs18 -5.5 (-14.4, 3.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 -0.2 (-7.4, 7.0) \cell +\pard\intbl\qc\fs18 7.1 (-3.2, 17.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10661 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2830 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4212 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5594 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6976 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8358 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10661 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10661 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae05/tsfae05.rtf b/tests/testthat/_snaps/tsfae05/tsfae05.rtf old mode 100755 new mode 100644 index 29a27b54..e6df8936 --- a/tests/testthat/_snaps/tsfae05/tsfae05.rtf +++ b/tests/testthat/_snaps/tsfae05/tsfae05.rtf @@ -1,17 +1,13 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2815 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5699 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7140 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8445 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10573 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE05:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE05:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,87 +17,67 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2815 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5699 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7140 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8445 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10573 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2863 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7608 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related AE \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 24 (19.0%) \cell -\pard\intbl\qc\fs18 8 (13.6%) \cell -\pard\intbl\qc\fs18 9.1 (-5.2, 23.3) \cell -\pard\intbl\qc\fs18 2.9 (-9.3, 15.1) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 non-serious AE \cell +\pard\intbl\qc\fs18 44 (65.7%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 82 (69.5%) \cell +\pard\intbl\qc\fs18 31 (48.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -111,195 +87,81 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 11.3 (2.8, 19.9) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 20 (29.9%) \cell +\pard\intbl\qc\fs18 15 (29.4%) \cell +\pard\intbl\qc\fs18 35 (29.7%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 4.2 (-4.3, 12.6) \cell -\pard\intbl\qc\fs18 -0.7 (-6.6, 5.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -309,141 +171,81 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 20 (39.2%) \cell +\pard\intbl\qc\fs18 35 (29.7%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 20 (16.9%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -453,51 +255,39 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -507,69 +297,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -579,51 +353,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -633,51 +409,39 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -687,87 +451,39 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5699 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7140 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8445 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10573 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2815 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5699 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7140 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8445 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10573 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -777,15 +493,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5699 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7140 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8445 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10573 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae05a/tsfae05a.rtf b/tests/testthat/_snaps/tsfae05a/tsfae05a.rtf deleted file mode 100755 index 616a817a..00000000 --- a/tests/testthat/_snaps/tsfae05a/tsfae05a.rtf +++ /dev/null @@ -1,1318 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2853 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4144 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5570 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6996 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8287 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10460 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE05a:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2853 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4144 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5570 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6996 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8287 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10460 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age Group: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 13 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related AE \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 3 (23.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25.0 (-5.0, 55.0) \cell -\pard\intbl\qc\fs18 20.0 (-15.1, 55.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 20.0 (-15.1, 55.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 20.0 (-15.1, 55.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age Group: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related AE \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 1.0 (-14.6, 16.5) \cell -\pard\intbl\qc\fs18 0.6 (-14.4, 15.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.9 (-5.3, 17.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 1.0 (-14.6, 16.5) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\pard\intbl\qc\fs18 -5.3 (-15.3, 4.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age Group: \u8805?75 years \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 80 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related AE \cell -\pard\intbl\qc\fs18 9 (31.0%) \cell -\pard\intbl\qc\fs18 10 (19.6%) \cell -\pard\intbl\qc\fs18 19 (23.8%) \cell -\pard\intbl\qc\fs18 7 (21.2%) \cell -\pard\intbl\qc\fs18 9.8 (-12.0, 31.7) \cell -\pard\intbl\qc\fs18 -1.6 (-19.3, 16.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 0.8 (-11.5, 13.1) \cell -\pard\intbl\qc\fs18 -6.1 (-14.2, 2.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 -6.1 (-14.2, 2.1) \cell -\pard\intbl\qc\fs18 -6.1 (-14.2, 2.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 6 (7.5%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 7.7 (-7.2, 22.7) \cell -\pard\intbl\qc\fs18 -2.1 (-11.9, 7.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0.4 (-8.4, 9.3) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 2.9 (-5.9, 11.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 -9.1 (-18.9, 0.7) \cell -\pard\intbl\qc\fs18 -9.1 (-18.9, 0.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 -9.1 (-18.9, 0.7) \cell -\pard\intbl\qc\fs18 -9.1 (-18.9, 0.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 9 (11.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 17.2 (3.5, 31.0) \cell -\pard\intbl\qc\fs18 7.8 (0.5, 15.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 5 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10.3 (-0.7, 21.4) \cell -\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.9 (-2.3, 16.1) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -1.1 (-8.0, 5.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 -6.1 (-14.2, 2.1) \cell -\pard\intbl\qc\fs18 -6.1 (-14.2, 2.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2853 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5570 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6996 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8287 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10460 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2853 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4144 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5570 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6996 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8287 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10460 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5570 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6996 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8287 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10460 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae10/tsfae10.rtf b/tests/testthat/_snaps/tsfae06/tsfae06.rtf old mode 100755 new mode 100644 similarity index 60% rename from tests/testthat/_snaps/tsfae10/tsfae10.rtf rename to tests/testthat/_snaps/tsfae06/tsfae06.rtf index cc3639b1..36172c97 --- a/tests/testthat/_snaps/tsfae10/tsfae10.rtf +++ b/tests/testthat/_snaps/tsfae06/tsfae06.rtf @@ -3,13 +3,13 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4107 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5400 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6693 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7986 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10344 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE10:\tab Dummy Title\b0 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2847 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3395 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3942 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4490 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6351 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE06:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,12 +21,12 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2814 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4107 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5400 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6693 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7986 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10344 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2847 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3395 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3942 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4490 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6351 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9526 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -39,35 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4107 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5400 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7986 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10344 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3395 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3942 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4490 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4107 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5400 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6693 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7986 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10344 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2847 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3395 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3942 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4490 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6351 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -75,48 +75,30 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4107 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5400 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6693 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7986 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10344 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4107 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5400 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6693 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7986 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10344 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2847 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3395 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3942 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4490 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6351 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9526 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Myocardial infarction \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4107 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5400 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6693 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7986 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10344 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2847 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3395 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3942 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4490 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6351 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9526 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -129,12 +111,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4107 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5400 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6693 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7986 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10344 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3395 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3942 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4490 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae06b/tsfae06b.rtf b/tests/testthat/_snaps/tsfae06b/tsfae06b.rtf deleted file mode 100755 index 9f6f69c0..00000000 --- a/tests/testthat/_snaps/tsfae06b/tsfae06b.rtf +++ /dev/null @@ -1,436 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2807 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4281 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5754 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7228 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8561 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10666 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE06b:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2807 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4281 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5754 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7228 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8561 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10666 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 27.6 (12.4, 42.7) \cell -\pard\intbl\qc\fs18 9.0 (-2.9, 20.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 17.7 (4.5, 31.0) \cell -\pard\intbl\qc\fs18 17.9 (6.1, 29.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 15.5 (4.0, 27.0) \cell -\pard\intbl\qc\fs18 11.7 (2.3, 21.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 12.5 (-1.2, 26.1) \cell -\pard\intbl\qc\fs18 0.8 (-9.7, 11.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 15.1 (5.5, 24.7) \cell -\pard\intbl\qc\fs18 11.0 (3.8, 18.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 11.7 (1.0, 22.4) \cell -\pard\intbl\qc\fs18 6.2 (-2.0, 14.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2.7 (-7.5, 12.8) \cell -\pard\intbl\qc\fs18 5.5 (-4.4, 15.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 11.7 (1.0, 22.4) \cell -\pard\intbl\qc\fs18 2.1 (-4.9, 9.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 13.2 (4.1, 22.3) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 6.8 (1.1, 12.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6.0 (-3.1, 15.2) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4.0 (-3.1, 11.0) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2807 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4281 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5754 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7228 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8561 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10666 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2807 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4281 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5754 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7228 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8561 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10666 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2807 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4281 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5754 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7228 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8561 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10666 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae07a/tsfae07a.rtf b/tests/testthat/_snaps/tsfae07a/tsfae07a.rtf old mode 100755 new mode 100644 index 8b05a8f8..7d86be64 --- a/tests/testthat/_snaps/tsfae07a/tsfae07a.rtf +++ b/tests/testthat/_snaps/tsfae07a/tsfae07a.rtf @@ -3,12 +3,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4212 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5573 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7064 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8424 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10433 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5645 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7056 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8468 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10685 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE07a:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,12 +21,12 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2852 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4212 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5573 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7064 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8424 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10433 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5645 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7056 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8468 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10685 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -39,35 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr AESI Assessment, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr AE of Interest Assessment, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -75,31 +75,31 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Seizure \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 45 (61.6%) \cell -\pard\intbl\qc\fs18 88 (69.8%) \cell -\pard\intbl\qc\fs18 24 (40.7%) \cell -\pard\intbl\qc\fs18 40.5 (24.1, 56.8) \cell -\pard\intbl\qc\fs18 21.0 (4.2, 37.7) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sensitivity \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 14 (21.9%) \cell +\pard\intbl\qc\fs18 6.5 (-8.3, 21.3) \cell +\pard\intbl\qc\fs18 21.3 (4.3, 38.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Preferred Term \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Preferred term \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -111,498 +111,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -0.6 (-11.8, 10.7) \cell +\pard\intbl\qc\fs18 9.1 (-4.8, 23.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 -3.0 (-11.2, 5.2) \cell -\pard\intbl\qc\fs18 -5.4 (-12.4, 1.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 8.5 (-3.7, 20.6) \cell +\pard\intbl\qc\fs18 24.4 (9.2, 39.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 13.2 (4.1, 22.3) \cell -\pard\intbl\qc\fs18 6.8 (1.1, 12.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 7.2 (-2.9, 17.3) \cell +\pard\intbl\qc\fs18 3.6 (-6.5, 13.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 -0.7 (-6.6, 5.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 6.5 (-0.6, 13.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2.7 (-7.5, 12.8) \cell -\pard\intbl\qc\fs18 -1.3 (-9.6, 7.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 7.9 (-1.8, 17.6) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 RASH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -615,13 +183,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Maximum severity \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Worst severity \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -633,66 +201,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Severe \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Moderate \cell -\pard\intbl\qc\fs18 22 (41.5%) \cell -\pard\intbl\qc\fs18 23 (31.5%) \cell -\pard\intbl\qc\fs18 45 (35.7%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 29.6 (14.0, 45.3) \cell -\pard\intbl\qc\fs18 19.6 (6.2, 33.1) \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 5.6 (-5.6, 16.7) \cell +\pard\intbl\qc\fs18 8.3 (-4.4, 20.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Mild \cell -\pard\intbl\qc\fs18 21 (39.6%) \cell -\pard\intbl\qc\fs18 19 (26.0%) \cell -\pard\intbl\qc\fs18 40 (31.7%) \cell -\pard\intbl\qc\fs18 17 (28.8%) \cell -\pard\intbl\qc\fs18 10.8 (-6.7, 28.3) \cell -\pard\intbl\qc\fs18 -2.8 (-18.1, 12.5) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 20 (16.9%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -0.6 (-11.8, 10.7) \cell +\pard\intbl\qc\fs18 11.0 (-3.2, 25.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -705,48 +273,48 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Serious \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 20 (27.4%) \cell -\pard\intbl\qc\fs18 43 (34.1%) \cell -\pard\intbl\qc\fs18 16 (27.1%) \cell -\pard\intbl\qc\fs18 16.3 (-1.2, 33.8) \cell -\pard\intbl\qc\fs18 0.3 (-15.0, 15.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SAE classification\super a\nosupersub \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 32 (27.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 5.2 (-8.4, 18.8) \cell +\pard\intbl\qc\fs18 16.1 (0.2, 32.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Deaths \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other medically important event \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 32 (27.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 5.2 (-8.4, 18.8) \cell +\pard\intbl\qc\fs18 16.1 (0.2, 32.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -759,30 +327,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Resulting in treatment discontinuation \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 1.0 (-9.6, 11.6) \cell -\pard\intbl\qc\fs18 -0.3 (-9.8, 9.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leading to permanent discontinuation of study treatment \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 1.3 (-6.4, 9.0) \cell +\pard\intbl\qc\fs18 7.1 (-3.2, 17.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -795,30 +363,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Related\super a\nosupersub \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 -1.1 (-10.1, 7.8) \cell -\pard\intbl\qc\fs18 -1.3 (-9.6, 7.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Related\super b\nosupersub \cell +\pard\intbl\qc\fs18 16 (23.9%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 38 (32.2%) \cell +\pard\intbl\qc\fs18 14 (21.9%) \cell +\pard\intbl\qc\fs18 2.0 (-12.4, 16.4) \cell +\pard\intbl\qc\fs18 21.3 (4.3, 38.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -831,66 +399,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Laboratory assessment\super b\nosupersub \cell -\pard\intbl\qc\fs18 52 (98.1%) \cell -\pard\intbl\qc\fs18 63 (86.3%) \cell -\pard\intbl\qc\fs18 115 (91.3%) \cell -\pard\intbl\qc\fs18 58 (98.3%) \cell -\pard\intbl\qc\fs18 -0.2 (-5.1, 4.7) \cell -\pard\intbl\qc\fs18 -12.0 (-20.6, -3.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Laboratory assessment\super c\nosupersub \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\pard\intbl\qc\fs18 8.0 (-6.6, 22.7) \cell +\pard\intbl\qc\fs18 22.8 (6.0, 39.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 AST>5xULN \cell -\pard\intbl\qc\fs18 49 (92.5%) \cell -\pard\intbl\qc\fs18 54 (74.0%) \cell -\pard\intbl\qc\fs18 103 (81.7%) \cell -\pard\intbl\qc\fs18 55 (93.2%) \cell -\pard\intbl\qc\fs18 -0.8 (-10.3, 8.8) \cell -\pard\intbl\qc\fs18 -19.2 (-31.2, -7.3) \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 36 (30.5%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 12.8 (-0.8, 26.4) \cell +\pard\intbl\qc\fs18 21.2 (5.6, 36.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10685 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ALT>5xULN \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 51 (69.9%) \cell -\pard\intbl\qc\fs18 102 (81.0%) \cell -\pard\intbl\qc\fs18 47 (79.7%) \cell -\pard\intbl\qc\fs18 16.6 (5.1, 28.0) \cell -\pard\intbl\qc\fs18 -9.8 (-24.5, 4.9) \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 12 (18.8%) \cell +\pard\intbl\qc\fs18 0.7 (-12.8, 14.1) \cell +\pard\intbl\qc\fs18 16.5 (0.3, 32.8) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4212 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5573 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7064 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8424 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10433 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5645 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7056 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8468 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10685 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -903,12 +471,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae07b/tsfae07b.rtf b/tests/testthat/_snaps/tsfae07b/tsfae07b.rtf old mode 100755 new mode 100644 index 8ea1e3f3..1b313109 --- a/tests/testthat/_snaps/tsfae07b/tsfae07b.rtf +++ b/tests/testthat/_snaps/tsfae07b/tsfae07b.rtf @@ -3,12 +3,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4212 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5573 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7064 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8424 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10433 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5675 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10742 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE07b:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,12 +21,12 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2852 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4212 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5573 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7064 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8424 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10433 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2838 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5675 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7094 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8513 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10742 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -39,35 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr AESI Assessment, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr AE of Interest Assessment, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -75,31 +75,31 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Seizure \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 45 (61.6%) \cell -\pard\intbl\qc\fs18 88 (69.8%) \cell -\pard\intbl\qc\fs18 24 (40.7%) \cell -\pard\intbl\qc\fs18 40.5 (24.1, 56.8) \cell -\pard\intbl\qc\fs18 21.0 (4.2, 37.7) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sensitivity \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 14 (21.9%) \cell +\pard\intbl\qc\fs18 6.5 (-8.3, 21.3) \cell +\pard\intbl\qc\fs18 21.3 (4.3, 38.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Preferred Term \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Preferred term \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -111,480 +111,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5.9 (-2.0, 13.7) \cell -\pard\intbl\qc\fs18 2.4 (-3.2, 8.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5.9 (-2.0, 13.7) \cell -\pard\intbl\qc\fs18 6.5 (-0.6, 13.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 4.2 (-4.3, 12.6) \cell -\pard\intbl\qc\fs18 3.5 (-3.9, 10.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 11.9 (0.3, 23.5) \cell -\pard\intbl\qc\fs18 1.8 (-6.3, 9.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 RASH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell -\pard\intbl\qc\fs18 -2.3 (-9.1, 4.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -0.6 (-11.8, 10.7) \cell +\pard\intbl\qc\fs18 9.1 (-4.8, 23.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -3.2 (-9.9, 3.5) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 8.5 (-3.7, 20.6) \cell +\pard\intbl\qc\fs18 24.4 (9.2, 39.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 7.2 (-2.9, 17.3) \cell +\pard\intbl\qc\fs18 3.6 (-6.5, 13.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -597,13 +183,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Maximum toxicity \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Worst toxicity \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -615,102 +201,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 17 (32.1%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 28 (22.2%) \cell -\pard\intbl\qc\fs18 9 (15.3%) \cell -\pard\intbl\qc\fs18 16.8 (1.3, 32.4) \cell -\pard\intbl\qc\fs18 -0.2 (-12.5, 12.1) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 -3.5 (-13.4, 6.4) \cell +\pard\intbl\qc\fs18 2.8 (-9.4, 14.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 10.0 (-1.1, 21.2) \cell -\pard\intbl\qc\fs18 7.2 (-2.2, 16.6) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 1.2 (-7.4, 9.9) \cell +\pard\intbl\qc\fs18 -0.4 (-9.1, 8.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 10.0 (-1.1, 21.2) \cell -\pard\intbl\qc\fs18 11.4 (1.2, 21.5) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 8.1 (-2.6, 18.8) \cell -\pard\intbl\qc\fs18 5.9 (-3.2, 15.0) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -723,48 +309,48 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Serious \cell -\pard\intbl\qc\fs18 24 (45.3%) \cell -\pard\intbl\qc\fs18 17 (23.3%) \cell -\pard\intbl\qc\fs18 41 (32.5%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 23.2 (6.2, 40.3) \cell -\pard\intbl\qc\fs18 1.3 (-13.1, 15.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SAE classification\super a\nosupersub \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 32 (27.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 5.2 (-8.4, 18.8) \cell +\pard\intbl\qc\fs18 16.1 (0.2, 32.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Deaths \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other medically important event \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 32 (27.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 5.2 (-8.4, 18.8) \cell +\pard\intbl\qc\fs18 16.1 (0.2, 32.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -777,30 +363,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Resulting in treatment discontinuation \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 -3.0 (-11.2, 5.2) \cell -\pard\intbl\qc\fs18 -1.3 (-9.6, 7.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leading to permanent discontinuation of study treatment \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 1.3 (-6.4, 9.0) \cell +\pard\intbl\qc\fs18 7.1 (-3.2, 17.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -813,30 +399,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Related\super a\nosupersub \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0.6 (-7.8, 8.9) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Related\super b\nosupersub \cell +\pard\intbl\qc\fs18 16 (23.9%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 38 (32.2%) \cell +\pard\intbl\qc\fs18 14 (21.9%) \cell +\pard\intbl\qc\fs18 2.0 (-12.4, 16.4) \cell +\pard\intbl\qc\fs18 21.3 (4.3, 38.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -849,66 +435,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Laboratory assessment\super b\nosupersub \cell -\pard\intbl\qc\fs18 52 (98.1%) \cell -\pard\intbl\qc\fs18 63 (86.3%) \cell -\pard\intbl\qc\fs18 115 (91.3%) \cell -\pard\intbl\qc\fs18 58 (98.3%) \cell -\pard\intbl\qc\fs18 -0.2 (-5.1, 4.7) \cell -\pard\intbl\qc\fs18 -12.0 (-20.6, -3.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Laboratory assessment\super c\nosupersub \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\pard\intbl\qc\fs18 8.0 (-6.6, 22.7) \cell +\pard\intbl\qc\fs18 22.8 (6.0, 39.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 AST>5xULN \cell -\pard\intbl\qc\fs18 49 (92.5%) \cell -\pard\intbl\qc\fs18 54 (74.0%) \cell -\pard\intbl\qc\fs18 103 (81.7%) \cell -\pard\intbl\qc\fs18 55 (93.2%) \cell -\pard\intbl\qc\fs18 -0.8 (-10.3, 8.8) \cell -\pard\intbl\qc\fs18 -19.2 (-31.2, -7.3) \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 36 (30.5%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 12.8 (-0.8, 26.4) \cell +\pard\intbl\qc\fs18 21.2 (5.6, 36.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4212 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5573 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7064 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8424 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10433 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10742 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ALT>5xULN \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 51 (69.9%) \cell -\pard\intbl\qc\fs18 102 (81.0%) \cell -\pard\intbl\qc\fs18 47 (79.7%) \cell -\pard\intbl\qc\fs18 16.6 (5.1, 28.0) \cell -\pard\intbl\qc\fs18 -9.8 (-24.5, 4.9) \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 12 (18.8%) \cell +\pard\intbl\qc\fs18 0.7 (-12.8, 14.1) \cell +\pard\intbl\qc\fs18 16.5 (0.3, 32.8) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4212 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5573 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7064 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8424 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10433 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5675 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10742 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -921,12 +507,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5573 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7064 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8424 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10433 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae19a/tsfae19a.rtf b/tests/testthat/_snaps/tsfae07c/tsfae07c.rtf old mode 100755 new mode 100644 similarity index 53% rename from tests/testthat/_snaps/tsfae19a/tsfae19a.rtf rename to tests/testthat/_snaps/tsfae07c/tsfae07c.rtf index 0d6668fc..3cab2b69 --- a/tests/testthat/_snaps/tsfae19a/tsfae19a.rtf +++ b/tests/testthat/_snaps/tsfae07c/tsfae07c.rtf @@ -3,12 +3,14 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2834 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4495 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4983 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6644 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9673 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE19a:\tab Dummy Title\b0 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4305 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5786 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7268 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8750 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10726 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE07c:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -19,14 +21,16 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2834 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4495 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4983 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6644 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9673 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4305 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5786 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7268 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8750 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10726 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell @@ -35,31 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4495 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4983 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6644 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9673 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr OCMQ (Narrow) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4305 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5786 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7268 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8750 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10726 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2834 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4495 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4983 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6644 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9673 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=29 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=34 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=23 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4305 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5786 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7268 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8750 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10726 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr AE of Interest Assessment, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -67,97 +75,127 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4495 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4983 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6644 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9673 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Erectile Dysfunction \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4305 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5786 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7268 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8750 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10726 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hypertension \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.3%) \cell -\pard\intbl\qc\fs18 -0.9 (-11.6, 9.8) \cell -\pard\intbl\qc\fs18 -4.3 (-12.7, 4.0) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4495 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4983 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9673 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERECTILE DYSFUNCTION \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.3%) \cell -\pard\intbl\qc\fs18 -0.9 (-11.6, 9.8) \cell -\pard\intbl\qc\fs18 -4.3 (-12.7, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4305 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7268 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8750 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10726 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4305 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7268 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8750 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10726 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sensitivity \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 14 (21.9%) \cell +\pard\intbl\qc\fs18 6.5 (-8.3, 21.3) \cell +\pard\intbl\qc\fs18 21.3 (4.3, 38.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4495 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4983 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9673 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4305 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7268 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8750 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10726 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2834 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4495 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4983 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6644 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9673 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gynecomastia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4305 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5786 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7268 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8750 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10726 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hearing disorders \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 11.9 (3.2, 20.6) \cell +\pard\intbl\qc\fs18 14.1 (3.7, 24.6) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2834 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4495 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4983 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6644 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9673 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4305 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5786 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7268 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8750 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10726 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4495 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4983 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6644 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9673 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4305 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5786 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7268 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8750 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10726 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsfae07d/tsfae07d.rtf b/tests/testthat/_snaps/tsfae07d/tsfae07d.rtf new file mode 100644 index 00000000..e8df78fe --- /dev/null +++ b/tests/testthat/_snaps/tsfae07d/tsfae07d.rtf @@ -0,0 +1,490 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5645 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7056 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8468 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10685 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE07d:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5645 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7056 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8468 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10685 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr AE of Interest Assessment, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sensitivity \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 14 (21.9%) \cell +\pard\intbl\qc\fs18 6.5 (-8.3, 21.3) \cell +\pard\intbl\qc\fs18 21.3 (4.3, 38.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Preferred term \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -0.6 (-11.8, 10.7) \cell +\pard\intbl\qc\fs18 9.1 (-4.8, 23.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 8.5 (-3.7, 20.6) \cell +\pard\intbl\qc\fs18 24.4 (9.2, 39.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 7.2 (-2.9, 17.3) \cell +\pard\intbl\qc\fs18 3.6 (-6.5, 13.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Worst severity \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Severe \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Moderate \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 5.6 (-5.6, 16.7) \cell +\pard\intbl\qc\fs18 8.3 (-4.4, 20.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Mild \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 20 (16.9%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -0.6 (-11.8, 10.7) \cell +\pard\intbl\qc\fs18 11.0 (-3.2, 25.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SAE classification\super a\nosupersub \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 32 (27.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 5.2 (-8.4, 18.8) \cell +\pard\intbl\qc\fs18 16.1 (0.2, 32.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other medically important event \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 32 (27.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 5.2 (-8.4, 18.8) \cell +\pard\intbl\qc\fs18 16.1 (0.2, 32.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leading to permanent discontinuation of study treatment \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 1.3 (-6.4, 9.0) \cell +\pard\intbl\qc\fs18 7.1 (-3.2, 17.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Related\super b\nosupersub \cell +\pard\intbl\qc\fs18 16 (23.9%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 38 (32.2%) \cell +\pard\intbl\qc\fs18 14 (21.9%) \cell +\pard\intbl\qc\fs18 2.0 (-12.4, 16.4) \cell +\pard\intbl\qc\fs18 21.3 (4.3, 38.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Laboratory assessment\super c\nosupersub \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\pard\intbl\qc\fs18 8.0 (-6.6, 22.7) \cell +\pard\intbl\qc\fs18 22.8 (6.0, 39.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 AST>5xULN \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 36 (30.5%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 12.8 (-0.8, 26.4) \cell +\pard\intbl\qc\fs18 21.2 (5.6, 36.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5645 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7056 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8468 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10685 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ALT>5xULN \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 12 (18.8%) \cell +\pard\intbl\qc\fs18 0.7 (-12.8, 14.1) \cell +\pard\intbl\qc\fs18 16.5 (0.3, 32.8) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5645 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7056 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8468 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10685 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5645 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7056 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8468 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10685 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae06a/tsfae06a.rtf b/tests/testthat/_snaps/tsfae07e/tsfae07e.rtf old mode 100755 new mode 100644 similarity index 58% rename from tests/testthat/_snaps/tsfae06a/tsfae06a.rtf rename to tests/testthat/_snaps/tsfae07e/tsfae07e.rtf index 1ce99adf..9130c947 --- a/tests/testthat/_snaps/tsfae06a/tsfae06a.rtf +++ b/tests/testthat/_snaps/tsfae07e/tsfae07e.rtf @@ -7,9 +7,9 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5675 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8378 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10472 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE06a:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10742 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE07e:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -25,8 +25,8 @@ \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4257 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5675 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7094 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8378 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10472 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8513 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10742 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -43,15 +43,15 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } @@ -61,13 +61,13 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr AE of Interest Assessment, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -79,15 +79,33 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 27.6 (12.4, 42.7) \cell -\pard\intbl\qc\fs18 9.0 (-2.9, 20.9) \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sensitivity \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 14 (21.9%) \cell +\pard\intbl\qc\fs18 6.5 (-8.3, 21.3) \cell +\pard\intbl\qc\fs18 21.3 (4.3, 38.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Preferred term \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -97,15 +115,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 17.7 (4.5, 31.0) \cell -\pard\intbl\qc\fs18 17.9 (6.1, 29.7) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -0.6 (-11.8, 10.7) \cell +\pard\intbl\qc\fs18 9.1 (-4.8, 23.0) \cell \row } @@ -115,15 +133,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 15.5 (4.0, 27.0) \cell -\pard\intbl\qc\fs18 11.7 (2.3, 21.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 8.5 (-3.7, 20.6) \cell +\pard\intbl\qc\fs18 24.4 (9.2, 39.5) \cell \row } @@ -133,15 +151,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 12.5 (-1.2, 26.1) \cell -\pard\intbl\qc\fs18 0.8 (-9.7, 11.3) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 7.2 (-2.9, 17.3) \cell +\pard\intbl\qc\fs18 3.6 (-6.5, 13.6) \cell \row } @@ -151,15 +169,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 15.1 (5.5, 24.7) \cell -\pard\intbl\qc\fs18 11.0 (3.8, 18.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -169,15 +187,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 11.7 (1.0, 22.4) \cell -\pard\intbl\qc\fs18 6.2 (-2.0, 14.4) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Worst toxicity \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -187,15 +205,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2.7 (-7.5, 12.8) \cell -\pard\intbl\qc\fs18 5.5 (-4.4, 15.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 -3.5 (-13.4, 6.4) \cell +\pard\intbl\qc\fs18 2.8 (-9.4, 14.9) \cell \row } @@ -205,15 +223,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 11.7 (1.0, 22.4) \cell -\pard\intbl\qc\fs18 2.1 (-4.9, 9.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 1.2 (-7.4, 9.9) \cell +\pard\intbl\qc\fs18 -0.4 (-9.1, 8.4) \cell \row } @@ -223,15 +241,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 -0.9 (-11.0, 9.1) \cell -\pard\intbl\qc\fs18 1.1 (-8.7, 10.9) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } @@ -241,15 +259,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 13.2 (4.1, 22.3) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 10.2 (0.9, 19.6) \cell \row } @@ -259,15 +277,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 6.8 (1.1, 12.6) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } @@ -277,15 +295,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -295,15 +313,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6.0 (-3.1, 15.2) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SAE classification\super a\nosupersub \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 32 (27.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 5.2 (-8.4, 18.8) \cell +\pard\intbl\qc\fs18 16.1 (0.2, 32.0) \cell \row } @@ -313,15 +331,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other medically important event \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 32 (27.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 5.2 (-8.4, 18.8) \cell +\pard\intbl\qc\fs18 16.1 (0.2, 32.0) \cell \row } @@ -331,15 +349,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4.0 (-3.1, 11.0) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -349,15 +367,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leading to permanent discontinuation of study treatment \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 1.3 (-6.4, 9.0) \cell +\pard\intbl\qc\fs18 7.1 (-3.2, 17.3) \cell \row } @@ -367,15 +385,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -385,15 +403,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Related\super b\nosupersub \cell +\pard\intbl\qc\fs18 16 (23.9%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 38 (32.2%) \cell +\pard\intbl\qc\fs18 14 (21.9%) \cell +\pard\intbl\qc\fs18 2.0 (-12.4, 16.4) \cell +\pard\intbl\qc\fs18 21.3 (4.3, 38.2) \cell \row } @@ -403,15 +421,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -421,15 +439,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0.6 (-7.8, 8.9) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Laboratory assessment\super c\nosupersub \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\pard\intbl\qc\fs18 8.0 (-6.6, 22.7) \cell +\pard\intbl\qc\fs18 22.8 (6.0, 39.6) \cell \row } @@ -439,15 +457,15 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 AST>5xULN \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 36 (30.5%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 12.8 (-0.8, 26.4) \cell +\pard\intbl\qc\fs18 21.2 (5.6, 36.9) \cell \row } @@ -457,15 +475,15 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5675 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10472 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 -4.7 (-13.5, 4.1) \cell -\pard\intbl\qc\fs18 -8.5 (-15.6, -1.4) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10742 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ALT>5xULN \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 12 (18.8%) \cell +\pard\intbl\qc\fs18 0.7 (-12.8, 14.1) \cell +\pard\intbl\qc\fs18 16.5 (0.3, 32.8) \cell \row } @@ -475,8 +493,8 @@ \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5675 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8378 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10472 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10742 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -493,8 +511,8 @@ \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10472 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10742 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae08/tsfae08.rtf b/tests/testthat/_snaps/tsfae08/tsfae08.rtf old mode 100755 new mode 100644 index e49e8090..1a319efb --- a/tests/testthat/_snaps/tsfae08/tsfae08.rtf +++ b/tests/testthat/_snaps/tsfae08/tsfae08.rtf @@ -1,13 +1,17 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE08:\tab Dummy Title\b0 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2830 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4212 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5594 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6976 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8358 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10530 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE08:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -17,67 +21,87 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2863 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4444 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6026 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7608 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2830 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4212 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5594 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6976 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8358 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10530 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 42 (79.2%) \cell -\pard\intbl\qc\fs18 48 (65.8%) \cell -\pard\intbl\qc\fs18 90 (71.4%) \cell -\pard\intbl\qc\fs18 24 (40.7%) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE leading to [dose modification] \cell +\pard\intbl\qc\fs18 45 (67.2%) \cell +\pard\intbl\qc\fs18 37 (72.5%) \cell +\pard\intbl\qc\fs18 82 (69.5%) \cell +\pard\intbl\qc\fs18 30 (46.9%) \cell +\pard\intbl\qc\fs18 20.3 (3.7, 36.9) \cell +\pard\intbl\qc\fs18 25.7 (8.4, 43.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -87,95 +111,159 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 20 (27.4%) \cell -\pard\intbl\qc\fs18 43 (34.1%) \cell -\pard\intbl\qc\fs18 8 (13.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 15.9 (2.4, 29.4) \cell +\pard\intbl\qc\fs18 30.6 (14.8, 46.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 20 (16.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 10.3 (1.1, 19.5) \cell +\pard\intbl\qc\fs18 18.4 (6.4, 30.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 10.4 (3.1, 17.8) \cell +\pard\intbl\qc\fs18 13.7 (4.3, 23.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2.8 (-5.4, 10.9) \cell +\pard\intbl\qc\fs18 7.1 (-3.2, 17.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2.8 (-5.4, 10.9) \cell +\pard\intbl\qc\fs18 1.2 (-7.1, 9.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -185,137 +273,249 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 16 (30.2%) \cell -\pard\intbl\qc\fs18 24 (32.9%) \cell -\pard\intbl\qc\fs18 40 (31.7%) \cell -\pard\intbl\qc\fs18 8 (13.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 36 (30.5%) \cell +\pard\intbl\qc\fs18 12 (18.8%) \cell +\pard\intbl\qc\fs18 8.1 (-6.2, 22.4) \cell +\pard\intbl\qc\fs18 16.5 (0.3, 32.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 19 (15.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 16 (13.6%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 8.6 (-2.4, 19.6) \cell +\pard\intbl\qc\fs18 2.0 (-8.5, 12.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 4.3 (-4.3, 12.8) \cell +\pard\intbl\qc\fs18 9.0 (-1.7, 19.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 1.2 (-7.4, 9.9) \cell +\pard\intbl\qc\fs18 1.6 (-7.9, 11.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell +\pard\intbl\qc\fs18 4.7 (-3.8, 13.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 11.7 (1.5, 22.0) \cell +\pard\intbl\qc\fs18 9.0 (-1.7, 19.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 7.4 (-0.1, 14.9) \cell +\pard\intbl\qc\fs18 6.3 (-1.7, 14.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 5.9 (-0.6, 12.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 -1.2 (-6.9, 4.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -325,39 +525,87 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 4.3 (-4.3, 12.8) \cell +\pard\intbl\qc\fs18 7.1 (-3.2, 17.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 4.4 (-2.0, 10.8) \cell +\pard\intbl\qc\fs18 8.2 (-0.5, 16.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 -1.2 (-6.9, 4.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -367,53 +615,249 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 -3.4 (-12.5, 5.7) \cell +\pard\intbl\qc\fs18 4.4 (-7.5, 16.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 9.8 (1.6, 18.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 2.8 (-5.0, 10.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -6.3 (-12.2, -0.3) \cell +\pard\intbl\qc\fs18 -6.3 (-12.2, -0.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 -4.8 (-12.6, 2.9) \cell +\pard\intbl\qc\fs18 0.0 (-9.9, 9.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -0.1 (-4.3, 4.1) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 -4.8 (-11.4, 1.8) \cell +\pard\intbl\qc\fs18 -4.3 (-11.3, 2.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -0.1 (-6.0, 5.8) \cell +\pard\intbl\qc\fs18 4.7 (-3.8, 13.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 4.3 (-2.8, 11.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -423,53 +867,69 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2.9 (-2.9, 8.7) \cell +\pard\intbl\qc\fs18 2.4 (-3.8, 8.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 3.9 (-1.4, 9.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -479,39 +939,105 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4212 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5594 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6976 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8358 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2830 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4212 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5594 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6976 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8358 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10530 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -521,11 +1047,15 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4212 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5594 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6976 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8358 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae09/tsfae09.rtf b/tests/testthat/_snaps/tsfae09/tsfae09.rtf old mode 100755 new mode 100644 index 07b9c195..b741beb8 --- a/tests/testthat/_snaps/tsfae09/tsfae09.rtf +++ b/tests/testthat/_snaps/tsfae09/tsfae09.rtf @@ -3,71 +3,63 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5675 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2849 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5620 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6851 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9853 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE09:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2838 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5675 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7094 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8513 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10607 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2849 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5620 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6851 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9853 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Incidence Rate Difference (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Incidence Rate Difference (95% CI) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (EAIR Per 100 SY) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -75,235 +67,577 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 56 (44.4%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 31.2 (13.8, 48.5) \cell -\pard\intbl\qc\fs18 10.2 (-5.4, 25.8) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subject years\super a\nosupersub \cell +\pard\intbl\qc\fs18 102.9 \cell +\pard\intbl\qc\fs18 70.6 \cell +\pard\intbl\qc\fs18 94.0 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (16.3) \cell +\pard\intbl\qc\fs18 18 (39.4) \cell +\pard\intbl\qc\fs18 7 (8.0) \cell +\pard\intbl\qc\fs18 8.22 (-2.44, 18.89) \cell +\pard\intbl\qc\fs18 31.32 (12.19, 50.46) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (18.0) \cell +\pard\intbl\qc\fs18 13 (25.3) \cell +\pard\intbl\qc\fs18 4 (4.5) \cell +\pard\intbl\qc\fs18 13.52 (3.43, 23.60) \cell +\pard\intbl\qc\fs18 20.87 (6.43, 35.32) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (9.4) \cell +\pard\intbl\qc\fs18 11 (20.6) \cell +\pard\intbl\qc\fs18 8 (9.8) \cell +\pard\intbl\qc\fs18 -0.34 (-9.73, 9.06) \cell +\pard\intbl\qc\fs18 10.81 (-3.09, 24.72) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (10.0) \cell +\pard\intbl\qc\fs18 9 (14.9) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 8.91 (2.03, 15.78) \cell +\pard\intbl\qc\fs18 13.78 (3.83, 23.72) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 21.4 (4.3, 38.4) \cell -\pard\intbl\qc\fs18 20.4 (4.9, 35.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (9.7) \cell +\pard\intbl\qc\fs18 8 (13.1) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 8.65 (1.96, 15.33) \cell +\pard\intbl\qc\fs18 12.03 (2.71, 21.34) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 19.4 (6.6, 32.3) \cell -\pard\intbl\qc\fs18 12.7 (2.3, 23.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (5.2) \cell +\pard\intbl\qc\fs18 7 (12.2) \cell +\pard\intbl\qc\fs18 3 (3.4) \cell +\pard\intbl\qc\fs18 1.81 (-4.15, 7.77) \cell +\pard\intbl\qc\fs18 8.78 (-1.02, 18.58) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 12.1 (-0.2, 24.4) \cell -\pard\intbl\qc\fs18 4.2 (-5.4, 13.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (6.3) \cell +\pard\intbl\qc\fs18 6 (9.4) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 5.27 (-0.23, 10.77) \cell +\pard\intbl\qc\fs18 8.33 (0.51, 16.16) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 13.8 (1.9, 25.7) \cell -\pard\intbl\qc\fs18 4.5 (-4.3, 13.3) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (2.9) \cell +\pard\intbl\qc\fs18 6 (9.3) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 1.87 (-2.06, 5.80) \cell +\pard\intbl\qc\fs18 8.18 (0.49, 15.88) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 4.3 (-5.3, 14.0) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.0) \cell +\pard\intbl\qc\fs18 5 (8.0) \cell +\pard\intbl\qc\fs18 2 (2.2) \cell +\pard\intbl\qc\fs18 -1.23 (-4.86, 2.40) \cell +\pard\intbl\qc\fs18 5.79 (-1.87, 13.44) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 -2.4 (-13.8, 9.0) \cell -\pard\intbl\qc\fs18 -7.8 (-17.2, 1.7) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (9.6) \cell +\pard\intbl\qc\fs18 5 (7.9) \cell +\pard\intbl\qc\fs18 4 (4.5) \cell +\pard\intbl\qc\fs18 5.12 (-2.58, 12.82) \cell +\pard\intbl\qc\fs18 3.43 (-4.83, 11.69) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (2.0) \cell +\pard\intbl\qc\fs18 5 (7.9) \cell +\pard\intbl\qc\fs18 2 (2.2) \cell +\pard\intbl\qc\fs18 -0.20 (-4.40, 4.01) \cell +\pard\intbl\qc\fs18 5.61 (-1.94, 13.17) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (4.1) \cell +\pard\intbl\qc\fs18 5 (7.7) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 3.00 (-1.51, 7.51) \cell +\pard\intbl\qc\fs18 6.60 (-0.44, 13.65) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (3.0) \cell +\pard\intbl\qc\fs18 5 (7.7) \cell +\pard\intbl\qc\fs18 2 (2.2) \cell +\pard\intbl\qc\fs18 0.82 (-3.73, 5.37) \cell +\pard\intbl\qc\fs18 5.47 (-1.89, 12.83) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (3.0) \cell +\pard\intbl\qc\fs18 4 (6.4) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 1.92 (-2.10, 5.93) \cell +\pard\intbl\qc\fs18 5.28 (-1.32, 11.88) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5675 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (3.0) \cell +\pard\intbl\qc\fs18 4 (6.1) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 1.94 (-2.05, 5.94) \cell +\pard\intbl\qc\fs18 5.06 (-1.30, 11.43) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (7.4) \cell +\pard\intbl\qc\fs18 4 (6.1) \cell +\pard\intbl\qc\fs18 3 (3.3) \cell +\pard\intbl\qc\fs18 4.08 (-2.56, 10.73) \cell +\pard\intbl\qc\fs18 2.81 (-4.28, 9.90) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (2.0) \cell +\pard\intbl\qc\fs18 4 (6.0) \cell +\pard\intbl\qc\fs18 0 (0.0) \cell +\pard\intbl\qc\fs18 1.99 (-0.77, 4.74) \cell +\pard\intbl\qc\fs18 6.03 (0.12, 11.94) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (3.0) \cell +\pard\intbl\qc\fs18 4 (5.9) \cell +\pard\intbl\qc\fs18 2 (2.3) \cell +\pard\intbl\qc\fs18 0.75 (-3.90, 5.39) \cell +\pard\intbl\qc\fs18 3.58 (-2.96, 10.13) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (2.0) \cell +\pard\intbl\qc\fs18 3 (4.6) \cell +\pard\intbl\qc\fs18 9 (11.3) \cell +\pard\intbl\qc\fs18 -9.33 (-17.23, -1.42) \cell +\pard\intbl\qc\fs18 -6.70 (-15.77, 2.38) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 (0.0) \cell +\pard\intbl\qc\fs18 3 (4.5) \cell +\pard\intbl\qc\fs18 2 (2.2) \cell +\pard\intbl\qc\fs18 -2.15 (-5.14, 0.83) \cell +\pard\intbl\qc\fs18 2.37 (-3.55, 8.30) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.0) \cell +\pard\intbl\qc\fs18 3 (4.5) \cell +\pard\intbl\qc\fs18 0 (0.0) \cell +\pard\intbl\qc\fs18 0.99 (-0.95, 2.92) \cell +\pard\intbl\qc\fs18 4.51 (-0.59, 9.61) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (2.0) \cell +\pard\intbl\qc\fs18 2 (3.0) \cell +\pard\intbl\qc\fs18 4 (4.3) \cell +\pard\intbl\qc\fs18 -2.29 (-7.33, 2.75) \cell +\pard\intbl\qc\fs18 -1.33 (-7.21, 4.56) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.0) \cell +\pard\intbl\qc\fs18 2 (2.9) \cell +\pard\intbl\qc\fs18 6 (7.0) \cell +\pard\intbl\qc\fs18 -6.03 (-11.98, -0.08) \cell +\pard\intbl\qc\fs18 -4.08 (-11.03, 2.87) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (4.1) \cell +\pard\intbl\qc\fs18 2 (2.9) \cell +\pard\intbl\qc\fs18 0 (0.0) \cell +\pard\intbl\qc\fs18 4.14 (0.08, 8.20) \cell +\pard\intbl\qc\fs18 2.91 (-1.12, 6.95) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 (0.0) \cell +\pard\intbl\qc\fs18 2 (2.8) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 -1.09 (-3.21, 1.04) \cell +\pard\intbl\qc\fs18 1.75 (-2.72, 6.23) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (2.0) \cell +\pard\intbl\qc\fs18 1 (1.4) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 0.91 (-2.58, 4.39) \cell +\pard\intbl\qc\fs18 0.36 (-3.19, 3.91) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (2.0) \cell +\pard\intbl\qc\fs18 1 (1.4) \cell +\pard\intbl\qc\fs18 2 (2.2) \cell +\pard\intbl\qc\fs18 -0.22 (-4.37, 3.93) \cell +\pard\intbl\qc\fs18 -0.80 (-4.96, 3.37) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.0) \cell +\pard\intbl\qc\fs18 1 (1.4) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 -0.08 (-2.92, 2.76) \cell +\pard\intbl\qc\fs18 0.36 (-3.12, 3.84) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (4.1) \cell +\pard\intbl\qc\fs18 1 (1.4) \cell +\pard\intbl\qc\fs18 0 (0.0) \cell +\pard\intbl\qc\fs18 4.14 (0.08, 8.20) \cell +\pard\intbl\qc\fs18 1.42 (-1.37, 4.21) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.0) \cell +\pard\intbl\qc\fs18 1 (1.4) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 -0.08 (-2.95, 2.80) \cell +\pard\intbl\qc\fs18 0.35 (-3.14, 3.83) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.0) \cell +\pard\intbl\qc\fs18 0 (0.0) \cell +\pard\intbl\qc\fs18 1 (1.1) \cell +\pard\intbl\qc\fs18 -0.09 (-2.92, 2.75) \cell +\pard\intbl\qc\fs18 -1.07 (-3.15, 1.02) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2849 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4234 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5620 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6851 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9853 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (3.0) \cell +\pard\intbl\qc\fs18 0 (0.0) \cell +\pard\intbl\qc\fs18 0 (0.0) \cell +\pard\intbl\qc\fs18 3.05 (-0.40, 6.50) \cell +\pard\intbl\qc\fs18 0.00 (0.00, 0.00) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2849 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5620 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6851 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9853 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4234 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5620 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6851 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9853 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell -\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsfae10a/tsfae10a.rtf b/tests/testthat/_snaps/tsfae10a/tsfae10a.rtf new file mode 100644 index 00000000..b62f3587 --- /dev/null +++ b/tests/testthat/_snaps/tsfae10a/tsfae10a.rtf @@ -0,0 +1,438 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2793 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5225 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7657 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10269 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE10a:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2793 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5225 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7657 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10269 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Characteristic \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 96 (81.4%) \cell +\pard\intbl\qc\fs18 38 (59.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sex, n/Ns (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Male \cell +\pard\intbl\qc\fs18 20/26 (76.9%) \cell +\pard\intbl\qc\fs18 24/27 (88.9%) \cell +\pard\intbl\qc\fs18 44/53 (83.0%) \cell +\pard\intbl\qc\fs18 15/23 (65.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Female \cell +\pard\intbl\qc\fs18 30/41 (73.2%) \cell +\pard\intbl\qc\fs18 22/24 (91.7%) \cell +\pard\intbl\qc\fs18 52/65 (80.0%) \cell +\pard\intbl\qc\fs18 23/41 (56.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age group (years), n/Ns (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?18 to <65 \cell +\pard\intbl\qc\fs18 4/4 (100.0%) \cell +\pard\intbl\qc\fs18 8/9 (88.9%) \cell +\pard\intbl\qc\fs18 12/13 (92.3%) \cell +\pard\intbl\qc\fs18 8/12 (66.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?65 to <75 \cell +\pard\intbl\qc\fs18 16/19 (84.2%) \cell +\pard\intbl\qc\fs18 13/15 (86.7%) \cell +\pard\intbl\qc\fs18 29/34 (85.3%) \cell +\pard\intbl\qc\fs18 7/16 (43.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?75 \cell +\pard\intbl\qc\fs18 30/44 (68.2%) \cell +\pard\intbl\qc\fs18 25/27 (92.6%) \cell +\pard\intbl\qc\fs18 55/71 (77.5%) \cell +\pard\intbl\qc\fs18 23/36 (63.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race, n/Ns (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 American Indian or Alaska Native \cell +\pard\intbl\qc\fs18 7/11 (63.6%) \cell +\pard\intbl\qc\fs18 6/6 (100.0%) \cell +\pard\intbl\qc\fs18 13/17 (76.5%) \cell +\pard\intbl\qc\fs18 3/4 (75.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Asian \cell +\pard\intbl\qc\fs18 5/6 (83.3%) \cell +\pard\intbl\qc\fs18 6/6 (100.0%) \cell +\pard\intbl\qc\fs18 11/12 (91.7%) \cell +\pard\intbl\qc\fs18 5/7 (71.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Black or African American \cell +\pard\intbl\qc\fs18 4/9 (44.4%) \cell +\pard\intbl\qc\fs18 2/2 (100.0%) \cell +\pard\intbl\qc\fs18 6/11 (54.5%) \cell +\pard\intbl\qc\fs18 6/10 (60.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs18 5/5 (100.0%) \cell +\pard\intbl\qc\fs18 6/6 (100.0%) \cell +\pard\intbl\qc\fs18 11/11 (100.0%) \cell +\pard\intbl\qc\fs18 5/6 (83.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 White \cell +\pard\intbl\qc\fs18 6/7 (85.7%) \cell +\pard\intbl\qc\fs18 8/8 (100.0%) \cell +\pard\intbl\qc\fs18 14/15 (93.3%) \cell +\pard\intbl\qc\fs18 3/5 (60.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Multiple \cell +\pard\intbl\qc\fs18 6/7 (85.7%) \cell +\pard\intbl\qc\fs18 7/7 (100.0%) \cell +\pard\intbl\qc\fs18 13/14 (92.9%) \cell +\pard\intbl\qc\fs18 3/5 (60.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not reported or unknown \cell +\pard\intbl\qc\fs18 11/14 (78.6%) \cell +\pard\intbl\qc\fs18 8/12 (66.7%) \cell +\pard\intbl\qc\fs18 19/26 (73.1%) \cell +\pard\intbl\qc\fs18 8/15 (53.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell +\pard\intbl\qc\fs18 6/8 (75.0%) \cell +\pard\intbl\qc\fs18 3/4 (75.0%) \cell +\pard\intbl\qc\fs18 9/12 (75.0%) \cell +\pard\intbl\qc\fs18 5/12 (41.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ethnicity, n/Ns (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hispanic or Latino \cell +\pard\intbl\qc\fs18 11/14 (78.6%) \cell +\pard\intbl\qc\fs18 15/16 (93.8%) \cell +\pard\intbl\qc\fs18 26/30 (86.7%) \cell +\pard\intbl\qc\fs18 5/10 (50.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not Hispanic or Latino \cell +\pard\intbl\qc\fs18 10/15 (66.7%) \cell +\pard\intbl\qc\fs18 11/13 (84.6%) \cell +\pard\intbl\qc\fs18 21/28 (75.0%) \cell +\pard\intbl\qc\fs18 13/15 (86.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2793 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5225 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7657 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10269 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not reported or unknown \cell +\pard\intbl\qc\fs18 29/38 (76.3%) \cell +\pard\intbl\qc\fs18 20/22 (90.9%) \cell +\pard\intbl\qc\fs18 49/60 (81.7%) \cell +\pard\intbl\qc\fs18 20/39 (51.3%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2793 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5225 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7657 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10269 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2793 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5225 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7657 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10269 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae20c/tsfae20c.rtf b/tests/testthat/_snaps/tsfae10b/tsfae10b.rtf old mode 100755 new mode 100644 similarity index 85% rename from tests/testthat/_snaps/tsfae20c/tsfae20c.rtf rename to tests/testthat/_snaps/tsfae10b/tsfae10b.rtf index 7866e6a5..b4b7472a --- a/tests/testthat/_snaps/tsfae20c/tsfae20c.rtf +++ b/tests/testthat/_snaps/tsfae10b/tsfae10b.rtf @@ -7,7 +7,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5300 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7767 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10234 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE20c:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE10b:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -36,8 +36,8 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row @@ -50,10 +50,10 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Characteristic \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } @@ -63,11 +63,11 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 Abdominal Pain \cell -\pard\intbl\qc\fs18 46 (86.8%) \cell -\pard\intbl\qc\fs18 54 (74.0%) \cell -\pard\intbl\qc\fs18 100 (79.4%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 SAE \cell +\pard\intbl\qc\fs18 43 (64.2%) \cell +\pard\intbl\qc\fs18 41 (80.4%) \cell +\pard\intbl\qc\fs18 84 (71.2%) \cell +\pard\intbl\qc\fs18 25 (39.1%) \cell \row } @@ -106,10 +106,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Male \cell -\pard\intbl\qc\fs18 28/29 (96.6%) \cell -\pard\intbl\qc\fs18 27/34 (79.4%) \cell -\pard\intbl\qc\fs18 55/63 (87.3%) \cell -\pard\intbl\qc\fs18 14/23 (60.9%) \cell +\pard\intbl\qc\fs18 16/26 (61.5%) \cell +\pard\intbl\qc\fs18 22/27 (81.5%) \cell +\pard\intbl\qc\fs18 38/53 (71.7%) \cell +\pard\intbl\qc\fs18 11/23 (47.8%) \cell \row } @@ -120,10 +120,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Female \cell -\pard\intbl\qc\fs18 18/24 (75.0%) \cell -\pard\intbl\qc\fs18 27/39 (69.2%) \cell -\pard\intbl\qc\fs18 45/63 (71.4%) \cell -\pard\intbl\qc\fs18 19/36 (52.8%) \cell +\pard\intbl\qc\fs18 27/41 (65.9%) \cell +\pard\intbl\qc\fs18 19/24 (79.2%) \cell +\pard\intbl\qc\fs18 46/65 (70.8%) \cell +\pard\intbl\qc\fs18 14/41 (34.1%) \cell \row } @@ -162,10 +162,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?18 to <65 \cell -\pard\intbl\qc\fs18 7/8 (87.5%) \cell -\pard\intbl\qc\fs18 3/5 (60.0%) \cell -\pard\intbl\qc\fs18 10/13 (76.9%) \cell -\pard\intbl\qc\fs18 3/7 (42.9%) \cell +\pard\intbl\qc\fs18 3/4 (75.0%) \cell +\pard\intbl\qc\fs18 8/9 (88.9%) \cell +\pard\intbl\qc\fs18 11/13 (84.6%) \cell +\pard\intbl\qc\fs18 5/12 (41.7%) \cell \row } @@ -176,10 +176,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?65 to <75 \cell -\pard\intbl\qc\fs18 12/16 (75.0%) \cell -\pard\intbl\qc\fs18 14/17 (82.4%) \cell -\pard\intbl\qc\fs18 26/33 (78.8%) \cell -\pard\intbl\qc\fs18 10/19 (52.6%) \cell +\pard\intbl\qc\fs18 11/19 (57.9%) \cell +\pard\intbl\qc\fs18 11/15 (73.3%) \cell +\pard\intbl\qc\fs18 22/34 (64.7%) \cell +\pard\intbl\qc\fs18 5/16 (31.3%) \cell \row } @@ -190,10 +190,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?75 \cell -\pard\intbl\qc\fs18 27/29 (93.1%) \cell -\pard\intbl\qc\fs18 37/51 (72.5%) \cell -\pard\intbl\qc\fs18 64/80 (80.0%) \cell -\pard\intbl\qc\fs18 20/33 (60.6%) \cell +\pard\intbl\qc\fs18 29/44 (65.9%) \cell +\pard\intbl\qc\fs18 22/27 (81.5%) \cell +\pard\intbl\qc\fs18 51/71 (71.8%) \cell +\pard\intbl\qc\fs18 15/36 (41.7%) \cell \row } @@ -232,10 +232,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 American Indian or Alaska Native \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 9/10 (90.0%) \cell -\pard\intbl\qc\fs18 14/15 (93.3%) \cell -\pard\intbl\qc\fs18 2/3 (66.7%) \cell +\pard\intbl\qc\fs18 6/11 (54.5%) \cell +\pard\intbl\qc\fs18 6/6 (100.0%) \cell +\pard\intbl\qc\fs18 12/17 (70.6%) \cell +\pard\intbl\qc\fs18 1/4 (25.0%) \cell \row } @@ -246,10 +246,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Asian \cell -\pard\intbl\qc\fs18 9/10 (90.0%) \cell -\pard\intbl\qc\fs18 6/9 (66.7%) \cell -\pard\intbl\qc\fs18 15/19 (78.9%) \cell -\pard\intbl\qc\fs18 3/5 (60.0%) \cell +\pard\intbl\qc\fs18 5/6 (83.3%) \cell +\pard\intbl\qc\fs18 5/6 (83.3%) \cell +\pard\intbl\qc\fs18 10/12 (83.3%) \cell +\pard\intbl\qc\fs18 4/7 (57.1%) \cell \row } @@ -260,10 +260,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Black or African American \cell -\pard\intbl\qc\fs18 3/3 (100.0%) \cell -\pard\intbl\qc\fs18 7/11 (63.6%) \cell -\pard\intbl\qc\fs18 10/14 (71.4%) \cell -\pard\intbl\qc\fs18 4/7 (57.1%) \cell +\pard\intbl\qc\fs18 3/9 (33.3%) \cell +\pard\intbl\qc\fs18 2/2 (100.0%) \cell +\pard\intbl\qc\fs18 5/11 (45.5%) \cell +\pard\intbl\qc\fs18 5/10 (50.0%) \cell \row } @@ -274,10 +274,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs18 6/7 (85.7%) \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 11/12 (91.7%) \cell \pard\intbl\qc\fs18 4/5 (80.0%) \cell +\pard\intbl\qc\fs18 4/6 (66.7%) \cell +\pard\intbl\qc\fs18 8/11 (72.7%) \cell +\pard\intbl\qc\fs18 2/6 (33.3%) \cell \row } @@ -288,10 +288,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 White \cell -\pard\intbl\qc\fs18 7/8 (87.5%) \cell +\pard\intbl\qc\fs18 5/7 (71.4%) \cell \pard\intbl\qc\fs18 6/8 (75.0%) \cell -\pard\intbl\qc\fs18 13/16 (81.2%) \cell -\pard\intbl\qc\fs18 4/7 (57.1%) \cell +\pard\intbl\qc\fs18 11/15 (73.3%) \cell +\pard\intbl\qc\fs18 1/5 (20.0%) \cell \row } @@ -302,9 +302,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Multiple \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 7/10 (70.0%) \cell -\pard\intbl\qc\fs18 15/18 (83.3%) \cell +\pard\intbl\qc\fs18 4/7 (57.1%) \cell +\pard\intbl\qc\fs18 7/7 (100.0%) \cell +\pard\intbl\qc\fs18 11/14 (78.6%) \cell \pard\intbl\qc\fs18 1/5 (20.0%) \cell \row } @@ -316,10 +316,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not reported or unknown \cell -\pard\intbl\qc\fs18 7/11 (63.6%) \cell -\pard\intbl\qc\fs18 9/12 (75.0%) \cell -\pard\intbl\qc\fs18 16/23 (69.6%) \cell -\pard\intbl\qc\fs18 11/17 (64.7%) \cell +\pard\intbl\qc\fs18 11/14 (78.6%) \cell +\pard\intbl\qc\fs18 8/12 (66.7%) \cell +\pard\intbl\qc\fs18 19/26 (73.1%) \cell +\pard\intbl\qc\fs18 7/15 (46.7%) \cell \row } @@ -330,10 +330,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell -\pard\intbl\qc\fs18 1/1 (100.0%) \cell \pard\intbl\qc\fs18 5/8 (62.5%) \cell -\pard\intbl\qc\fs18 6/9 (66.7%) \cell -\pard\intbl\qc\fs18 4/10 (40.0%) \cell +\pard\intbl\qc\fs18 3/4 (75.0%) \cell +\pard\intbl\qc\fs18 8/12 (66.7%) \cell +\pard\intbl\qc\fs18 4/12 (33.3%) \cell \row } @@ -372,10 +372,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hispanic or Latino \cell -\pard\intbl\qc\fs18 12/15 (80.0%) \cell -\pard\intbl\qc\fs18 12/15 (80.0%) \cell +\pard\intbl\qc\fs18 10/14 (71.4%) \cell +\pard\intbl\qc\fs18 14/16 (87.5%) \cell \pard\intbl\qc\fs18 24/30 (80.0%) \cell -\pard\intbl\qc\fs18 6/12 (50.0%) \cell +\pard\intbl\qc\fs18 2/10 (20.0%) \cell \row } @@ -386,10 +386,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not Hispanic or Latino \cell -\pard\intbl\qc\fs18 13/15 (86.7%) \cell -\pard\intbl\qc\fs18 12/18 (66.7%) \cell -\pard\intbl\qc\fs18 25/33 (75.8%) \cell -\pard\intbl\qc\fs18 10/16 (62.5%) \cell +\pard\intbl\qc\fs18 8/15 (53.3%) \cell +\pard\intbl\qc\fs18 10/13 (76.9%) \cell +\pard\intbl\qc\fs18 18/28 (64.3%) \cell +\pard\intbl\qc\fs18 9/15 (60.0%) \cell \row } @@ -400,10 +400,10 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7767 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not reported or unknown \cell -\pard\intbl\qc\fs18 21/23 (91.3%) \cell -\pard\intbl\qc\fs18 30/40 (75.0%) \cell -\pard\intbl\qc\fs18 51/63 (81.0%) \cell -\pard\intbl\qc\fs18 17/31 (54.8%) \cell +\pard\intbl\qc\fs18 25/38 (65.8%) \cell +\pard\intbl\qc\fs18 17/22 (77.3%) \cell +\pard\intbl\qc\fs18 42/60 (70.0%) \cell +\pard\intbl\qc\fs18 14/39 (35.9%) \cell \row } diff --git a/tests/testthat/_snaps/tsfae10c/tsfae10c.rtf b/tests/testthat/_snaps/tsfae10c/tsfae10c.rtf new file mode 100644 index 00000000..2886ac12 --- /dev/null +++ b/tests/testthat/_snaps/tsfae10c/tsfae10c.rtf @@ -0,0 +1,466 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2856 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5317 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7779 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10437 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE10c:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2856 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5317 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7779 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10437 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Characteristic \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sex, n/Ns (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Male \cell +\pard\intbl\qc\fs18 5/26 (19.2%) \cell +\pard\intbl\qc\fs18 7/27 (25.9%) \cell +\pard\intbl\qc\fs18 12/53 (22.6%) \cell +\pard\intbl\qc\fs18 1/23 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Female \cell +\pard\intbl\qc\fs18 4/41 (9.8%) \cell +\pard\intbl\qc\fs18 1/24 (4.2%) \cell +\pard\intbl\qc\fs18 5/65 (7.7%) \cell +\pard\intbl\qc\fs18 0/41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age group (years), n/Ns (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?18 to <65 \cell +\pard\intbl\qc\fs18 0/4 \cell +\pard\intbl\qc\fs18 1/9 (11.1%) \cell +\pard\intbl\qc\fs18 1/13 (7.7%) \cell +\pard\intbl\qc\fs18 1/12 (8.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?65 to <75 \cell +\pard\intbl\qc\fs18 5/19 (26.3%) \cell +\pard\intbl\qc\fs18 2/15 (13.3%) \cell +\pard\intbl\qc\fs18 7/34 (20.6%) \cell +\pard\intbl\qc\fs18 0/16 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?75 \cell +\pard\intbl\qc\fs18 4/44 (9.1%) \cell +\pard\intbl\qc\fs18 5/27 (18.5%) \cell +\pard\intbl\qc\fs18 9/71 (12.7%) \cell +\pard\intbl\qc\fs18 0/36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race, n/Ns (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 American Indian or Alaska Native \cell +\pard\intbl\qc\fs18 2/11 (18.2%) \cell +\pard\intbl\qc\fs18 1/6 (16.7%) \cell +\pard\intbl\qc\fs18 3/17 (17.6%) \cell +\pard\intbl\qc\fs18 0/4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Asian \cell +\pard\intbl\qc\fs18 1/6 (16.7%) \cell +\pard\intbl\qc\fs18 2/6 (33.3%) \cell +\pard\intbl\qc\fs18 3/12 (25.0%) \cell +\pard\intbl\qc\fs18 0/7 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Black or African American \cell +\pard\intbl\qc\fs18 0/9 \cell +\pard\intbl\qc\fs18 0/2 \cell +\pard\intbl\qc\fs18 0/11 \cell +\pard\intbl\qc\fs18 0/10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Native Hawaiian or other Pacific Islander \cell +\pard\intbl\qc\fs18 3/5 (60.0%) \cell +\pard\intbl\qc\fs18 0/6 \cell +\pard\intbl\qc\fs18 3/11 (27.3%) \cell +\pard\intbl\qc\fs18 0/6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 White \cell +\pard\intbl\qc\fs18 0/7 \cell +\pard\intbl\qc\fs18 1/8 (12.5%) \cell +\pard\intbl\qc\fs18 1/15 (6.7%) \cell +\pard\intbl\qc\fs18 0/5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Multiple \cell +\pard\intbl\qc\fs18 0/7 \cell +\pard\intbl\qc\fs18 2/7 (28.6%) \cell +\pard\intbl\qc\fs18 2/14 (14.3%) \cell +\pard\intbl\qc\fs18 0/5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not reported \cell +\pard\intbl\qc\fs18 1/8 (12.5%) \cell +\pard\intbl\qc\fs18 1/4 (25.0%) \cell +\pard\intbl\qc\fs18 2/12 (16.7%) \cell +\pard\intbl\qc\fs18 1/7 (14.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Unknown \cell +\pard\intbl\qc\fs18 2/6 (33.3%) \cell +\pard\intbl\qc\fs18 0/8 \cell +\pard\intbl\qc\fs18 2/14 (14.3%) \cell +\pard\intbl\qc\fs18 0/8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell +\pard\intbl\qc\fs18 0/8 \cell +\pard\intbl\qc\fs18 1/4 (25.0%) \cell +\pard\intbl\qc\fs18 1/12 (8.3%) \cell +\pard\intbl\qc\fs18 0/12 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ethnicity, n/Ns (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hispanic or Latino \cell +\pard\intbl\qc\fs18 0/14 \cell +\pard\intbl\qc\fs18 1/16 (6.3%) \cell +\pard\intbl\qc\fs18 1/30 (3.3%) \cell +\pard\intbl\qc\fs18 0/10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not Hispanic or Latino \cell +\pard\intbl\qc\fs18 2/15 (13.3%) \cell +\pard\intbl\qc\fs18 4/13 (30.8%) \cell +\pard\intbl\qc\fs18 6/28 (21.4%) \cell +\pard\intbl\qc\fs18 0/15 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not reported \cell +\pard\intbl\qc\fs18 2/22 (9.1%) \cell +\pard\intbl\qc\fs18 0/10 \cell +\pard\intbl\qc\fs18 2/32 (6.3%) \cell +\pard\intbl\qc\fs18 1/19 (5.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2856 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5317 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7779 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10437 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Unknown \cell +\pard\intbl\qc\fs18 5/16 (31.3%) \cell +\pard\intbl\qc\fs18 3/12 (25.0%) \cell +\pard\intbl\qc\fs18 8/28 (28.6%) \cell +\pard\intbl\qc\fs18 0/20 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2856 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5317 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7779 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10437 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5317 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7779 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10437 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae11/tsfae11.rtf b/tests/testthat/_snaps/tsfae11/tsfae11.rtf deleted file mode 100755 index 1db32b08..00000000 --- a/tests/testthat/_snaps/tsfae11/tsfae11.rtf +++ /dev/null @@ -1,742 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4256 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5653 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7049 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8446 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10507 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE11:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2860 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4256 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5653 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7049 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8446 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10507 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 56 (44.4%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 31.2 (13.8, 48.5) \cell -\pard\intbl\qc\fs18 10.2 (-5.4, 25.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 27.6 (12.4, 42.7) \cell -\pard\intbl\qc\fs18 9.0 (-2.9, 20.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 12.5 (-1.2, 26.1) \cell -\pard\intbl\qc\fs18 0.8 (-9.7, 11.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2.7 (-7.5, 12.8) \cell -\pard\intbl\qc\fs18 5.5 (-4.4, 15.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 11.7 (1.0, 22.4) \cell -\pard\intbl\qc\fs18 2.1 (-4.9, 9.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 21.4 (4.3, 38.4) \cell -\pard\intbl\qc\fs18 20.4 (4.9, 35.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 17.7 (4.5, 31.0) \cell -\pard\intbl\qc\fs18 17.9 (6.1, 29.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 15.5 (4.0, 27.0) \cell -\pard\intbl\qc\fs18 11.7 (2.3, 21.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 11.7 (1.0, 22.4) \cell -\pard\intbl\qc\fs18 6.2 (-2.0, 14.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 -0.9 (-11.0, 9.1) \cell -\pard\intbl\qc\fs18 1.1 (-8.7, 10.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 6.8 (1.1, 12.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 19.4 (6.6, 32.3) \cell -\pard\intbl\qc\fs18 12.7 (2.3, 23.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 15.1 (5.5, 24.7) \cell -\pard\intbl\qc\fs18 11.0 (3.8, 18.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6.0 (-3.1, 15.2) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 12.1 (-0.2, 24.4) \cell -\pard\intbl\qc\fs18 4.2 (-5.4, 13.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 13.8 (1.9, 25.7) \cell -\pard\intbl\qc\fs18 4.5 (-4.3, 13.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 13.2 (4.1, 22.3) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0.6 (-7.8, 8.9) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 4.3 (-5.3, 14.0) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4.0 (-3.1, 11.0) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 -2.4 (-13.8, 9.0) \cell -\pard\intbl\qc\fs18 -7.8 (-17.2, 1.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4256 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5653 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7049 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8446 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10507 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 -4.7 (-13.5, 4.1) \cell -\pard\intbl\qc\fs18 -8.5 (-15.6, -1.4) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4256 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5653 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7049 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8446 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10507 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4256 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5653 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7049 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8446 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10507 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae11a/tsfae11apart1of2.rtf b/tests/testthat/_snaps/tsfae11a/tsfae11apart1of2.rtf new file mode 100644 index 00000000..e2bc484e --- /dev/null +++ b/tests/testthat/_snaps/tsfae11a/tsfae11apart1of2.rtf @@ -0,0 +1,1346 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2837 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4131 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5426 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6721 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7769 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9064 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10358 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11653 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE11apart1of2:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2837 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4131 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5426 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6721 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7769 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9064 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10358 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11653 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx4131 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5426 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx6721 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7769 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx9064 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx10358 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx11653 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5426 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6721 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10358 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11653 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell +\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell +\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell +\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell +\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4131 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5426 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6721 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9064 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10358 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11653 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\pard\intbl\qc\fs18 \keepn\trhdr Mild \cell +\pard\intbl\qc\fs18 \keepn\trhdr Moderate \cell +\pard\intbl\qc\fs18 \keepn\trhdr Severe \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\pard\intbl\qc\fs18 \keepn\trhdr Mild \cell +\pard\intbl\qc\fs18 \keepn\trhdr Moderate \cell +\pard\intbl\qc\fs18 \keepn\trhdr Severe \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4131 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5426 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6721 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7769 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9064 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10358 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11653 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2837 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4131 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5426 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6721 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7769 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9064 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10358 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11653 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4131 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5426 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6721 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7769 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9064 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10358 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11653 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae21bpart2/tsfae21bpart2of4.rtf b/tests/testthat/_snaps/tsfae11b/tsfae11bpart1of4.rtf old mode 100755 new mode 100644 similarity index 73% rename from tests/testthat/_snaps/tsfae21bpart2/tsfae21bpart2of4.rtf rename to tests/testthat/_snaps/tsfae11b/tsfae11bpart1of4.rtf index 7dfbb9e7..4328808b --- a/tests/testthat/_snaps/tsfae21bpart2/tsfae21bpart2of4.rtf +++ b/tests/testthat/_snaps/tsfae11b/tsfae11bpart1of4.rtf @@ -8,8 +8,8 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6174 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7674 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9173 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11025 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE21bpart2of4:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10849 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE11bpart1of4:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -26,7 +26,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6174 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7674 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9173 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11025 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10849 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -44,7 +44,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell @@ -62,14 +62,14 @@ \clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6174 \clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7674 \clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9173 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11025 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10849 \clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell \row } @@ -80,7 +80,7 @@ \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6174 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7674 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9173 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11025 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10849 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell @@ -98,7 +98,7 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6174 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7674 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9173 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11025 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10849 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell \pard\intbl\qc\fs18 \keepn\trhdr 1 \cell @@ -116,9 +116,9 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -134,7 +134,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -152,14 +152,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell \row } @@ -170,14 +170,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell \row } @@ -188,14 +188,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \row } @@ -206,14 +206,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -224,14 +224,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \row } @@ -242,14 +242,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -260,14 +260,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \row } @@ -278,14 +278,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -296,14 +296,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -314,14 +314,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell \row } @@ -332,14 +332,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \row } @@ -350,14 +350,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \row } @@ -368,14 +368,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \row } @@ -386,13 +386,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -404,14 +404,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -422,13 +422,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -440,7 +440,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -458,14 +458,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \row } @@ -476,14 +476,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \row } @@ -494,14 +494,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -512,14 +512,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -530,13 +530,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -548,7 +548,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -566,14 +566,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -584,14 +584,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \row } @@ -602,13 +602,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -620,14 +620,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \row } @@ -638,14 +638,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -656,7 +656,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -674,14 +674,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \row } @@ -692,14 +692,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \row } @@ -710,14 +710,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -728,14 +728,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \row } @@ -746,7 +746,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -764,14 +764,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -782,14 +782,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -800,11 +800,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -818,7 +818,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -836,13 +836,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -854,13 +854,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -872,8 +872,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -890,7 +890,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -908,14 +908,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \row } @@ -926,14 +926,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -944,14 +944,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -962,7 +962,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -980,68 +980,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -1052,14 +998,14 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \row } @@ -1070,7 +1016,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1088,8 +1034,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -1106,8 +1052,8 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6174 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7674 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9173 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11025 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -1124,7 +1070,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6174 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7674 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9173 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11025 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10849 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -1142,7 +1088,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6174 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7674 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9173 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11025 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae11c/tsfae11c.rtf b/tests/testthat/_snaps/tsfae11c/tsfae11c.rtf new file mode 100644 index 00000000..0921207c --- /dev/null +++ b/tests/testthat/_snaps/tsfae11c/tsfae11c.rtf @@ -0,0 +1,2202 @@ +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2108 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3878 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5649 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7419 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE11c:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2108 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3878 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5649 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7419 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 96 (81.4%) \cell +\pard\intbl\qc\fs18 38 (59.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 28 (23.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 27 (22.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 16 (13.6%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2108 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3878 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5649 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7419 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae11d/tsfae11d.rtf b/tests/testthat/_snaps/tsfae11d/tsfae11d.rtf new file mode 100644 index 00000000..b6233679 --- /dev/null +++ b/tests/testthat/_snaps/tsfae11d/tsfae11d.rtf @@ -0,0 +1,3140 @@ +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2108 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3878 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5649 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7419 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE11d:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2108 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3878 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5649 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7419 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 96 (81.4%) \cell +\pard\intbl\qc\fs18 38 (59.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 28 (23.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 27 (22.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 16 (13.6%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2108 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3878 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5649 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7419 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2108 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3878 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5649 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7419 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae12a/tsfae12apart1of4.rtf b/tests/testthat/_snaps/tsfae12a/tsfae12apart1of4.rtf new file mode 100644 index 00000000..7b2af6da --- /dev/null +++ b/tests/testthat/_snaps/tsfae12a/tsfae12apart1of4.rtf @@ -0,0 +1,996 @@ +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2115 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3647 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5032 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6418 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7804 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE12apart1of4:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2115 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3647 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5032 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6418 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7804 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3647 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5032 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6418 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7804 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5032 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6418 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7804 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Race \cell +\pard\intbl\qc\fs18 \keepn\trhdr Race \cell +\pard\intbl\qc\fs18 \keepn\trhdr Race \cell +\pard\intbl\qc\fs18 \keepn\trhdr Race \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3647 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5032 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6418 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7804 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\pard\intbl\qc\fs18 \keepn\trhdr White \cell +\pard\intbl\qc\fs18 \keepn\trhdr Black \cell +\pard\intbl\qc\fs18 \keepn\trhdr Asian \cell +\pard\intbl\qc\fs18 \keepn\trhdr Other \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell +\pard\intbl\qc\fs18 39 (73.6%) \cell +\pard\intbl\qc\fs18 6 (85.7%) \cell +\pard\intbl\qc\fs18 4 (44.4%) \cell +\pard\intbl\qc\fs18 5 (83.3%) \cell +\pard\intbl\qc\fs18 6 (75.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 19 (35.8%) \cell +\pard\intbl\qc\fs18 1 (14.3%) \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 6 (75.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 11 (20.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 5 (62.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 7 (13.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 3 (37.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (13.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (25.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 1 (14.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 15 (28.3%) \cell +\pard\intbl\qc\fs18 4 (57.1%) \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 2 (33.3%) \cell +\pard\intbl\qc\fs18 1 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 12 (22.6%) \cell +\pard\intbl\qc\fs18 3 (42.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (33.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 7 (13.2%) \cell +\pard\intbl\qc\fs18 2 (28.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 5 (9.4%) \cell +\pard\intbl\qc\fs18 2 (28.6%) \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 1 (14.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 10 (18.9%) \cell +\pard\intbl\qc\fs18 1 (14.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (33.3%) \cell +\pard\intbl\qc\fs18 2 (25.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 6 (11.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 1 (14.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 1 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 5 (9.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (25.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (16.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 1 (14.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 1 (14.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2115 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3647 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5032 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6418 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7804 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2115 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3647 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5032 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6418 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7804 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2115 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3647 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5032 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6418 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7804 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae22bpart1/tsfae22bpart1of2.rtf b/tests/testthat/_snaps/tsfae12b/tsfae12bpart1of2.rtf old mode 100755 new mode 100644 similarity index 77% rename from tests/testthat/_snaps/tsfae22bpart1/tsfae22bpart1of2.rtf rename to tests/testthat/_snaps/tsfae12b/tsfae12bpart1of2.rtf index 25a11408..bb377f10 --- a/tests/testthat/_snaps/tsfae22bpart1/tsfae22bpart1of2.rtf +++ b/tests/testthat/_snaps/tsfae12b/tsfae12bpart1of2.rtf @@ -9,7 +9,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5659 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6836 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8013 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE22bpart1of2:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE12bpart1of2:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -46,12 +46,12 @@ \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx6836 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx8013 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline Low Dose \cell \pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline Low Dose \cell \pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell \row } @@ -100,12 +100,12 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 27 \cell \pard\intbl\qc\fs18 24 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 34 \cell -\pard\intbl\qc\fs18 39 \cell \row } @@ -136,12 +136,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 28 (96.6%) \cell -\pard\intbl\qc\fs18 23 (95.8%) \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 27 (79.4%) \cell -\pard\intbl\qc\fs18 28 (71.8%) \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 20 (76.9%) \cell +\pard\intbl\qc\fs18 30 (73.2%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 24 (88.9%) \cell +\pard\intbl\qc\fs18 22 (91.7%) \cell \row } @@ -171,13 +171,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 19 (65.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 11 (42.3%) \cell +\pard\intbl\qc\fs18 14 (34.1%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 12 (44.4%) \cell \pard\intbl\qc\fs18 11 (45.8%) \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 13 (38.2%) \cell -\pard\intbl\qc\fs18 13 (33.3%) \cell \row } @@ -189,13 +189,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 10 (34.5%) \cell -\pard\intbl\qc\fs18 10 (41.7%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 8 (23.5%) \cell -\pard\intbl\qc\fs18 6 (15.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 7 (26.9%) \cell +\pard\intbl\qc\fs18 8 (19.5%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 8 (29.6%) \cell +\pard\intbl\qc\fs18 5 (20.8%) \cell \row } @@ -207,13 +207,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 6 (20.7%) \cell -\pard\intbl\qc\fs18 6 (25.0%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 4 (11.8%) \cell -\pard\intbl\qc\fs18 4 (10.3%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (19.2%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 6 (22.2%) \cell +\pard\intbl\qc\fs18 3 (12.5%) \cell \row } @@ -225,13 +225,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 5 (14.7%) \cell -\pard\intbl\qc\fs18 4 (10.3%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 4 (16.7%) \cell \row } @@ -243,13 +243,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 6 (20.7%) \cell -\pard\intbl\qc\fs18 2 (8.3%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (8.8%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 3 (12.5%) \cell \row } @@ -261,13 +261,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 3 (7.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 4 (16.7%) \cell \row } @@ -279,13 +279,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 2 (8.3%) \cell \row } @@ -297,13 +297,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -315,13 +315,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 13 (44.8%) \cell -\pard\intbl\qc\fs18 10 (41.7%) \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 15 (44.1%) \cell -\pard\intbl\qc\fs18 16 (41.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -333,13 +333,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 9 (31.0%) \cell -\pard\intbl\qc\fs18 4 (16.7%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 9 (26.5%) \cell -\pard\intbl\qc\fs18 9 (23.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 8 (30.8%) \cell +\pard\intbl\qc\fs18 15 (36.6%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 16 (59.3%) \cell +\pard\intbl\qc\fs18 9 (37.5%) \cell \row } @@ -351,13 +351,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 6 (20.7%) \cell -\pard\intbl\qc\fs18 4 (16.7%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 8 (23.5%) \cell -\pard\intbl\qc\fs18 3 (7.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 6 (23.1%) \cell +\pard\intbl\qc\fs18 7 (17.1%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 9 (33.3%) \cell +\pard\intbl\qc\fs18 9 (37.5%) \cell \row } @@ -369,13 +369,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\pard\intbl\qc\fs18 4 (16.7%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell -\pard\intbl\qc\fs18 5 (12.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\pard\intbl\qc\fs18 6 (14.6%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 5 (18.5%) \cell +\pard\intbl\qc\fs18 6 (25.0%) \cell \row } @@ -387,13 +387,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 2 (8.3%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 4 (11.8%) \cell -\pard\intbl\qc\fs18 3 (7.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\pard\intbl\qc\fs18 6 (14.6%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 4 (14.8%) \cell +\pard\intbl\qc\fs18 1 (4.2%) \cell \row } @@ -405,13 +405,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 4 (16.7%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 4 (11.8%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 4 (14.8%) \cell +\pard\intbl\qc\fs18 1 (4.2%) \cell \row } @@ -423,13 +423,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 3 (12.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (8.8%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (14.8%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -441,13 +441,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell \row } @@ -478,12 +478,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 8 (27.6%) \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 7 (26.9%) \cell +\pard\intbl\qc\fs18 7 (17.1%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 8 (29.6%) \cell \pard\intbl\qc\fs18 5 (20.8%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 8 (23.5%) \cell -\pard\intbl\qc\fs18 5 (12.8%) \cell \row } @@ -495,13 +495,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 7 (24.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (19.2%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 7 (25.9%) \cell \pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 5 (14.7%) \cell -\pard\intbl\qc\fs18 3 (7.7%) \cell \row } @@ -513,13 +513,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 4 (16.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (8.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 3 (12.5%) \cell \row } @@ -531,13 +531,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 2 (8.3%) \cell \row } @@ -549,12 +549,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -586,12 +586,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 7 (24.1%) \cell -\pard\intbl\qc\fs18 3 (12.5%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 5 (14.7%) \cell -\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 8 (29.6%) \cell +\pard\intbl\qc\fs18 4 (16.7%) \cell \row } @@ -603,13 +603,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 3 (12.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 4 (16.7%) \cell \row } @@ -621,13 +621,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 5 (18.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell \row } @@ -639,12 +639,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (8.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -657,13 +657,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell \row } @@ -694,12 +694,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 7 (24.1%) \cell -\pard\intbl\qc\fs18 3 (12.5%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 4 (11.8%) \cell -\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 4 (15.4%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 6 (22.2%) \cell +\pard\intbl\qc\fs18 2 (8.3%) \cell \row } @@ -711,13 +711,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\pard\intbl\qc\fs18 2 (8.3%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (8.8%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 5 (18.5%) \cell +\pard\intbl\qc\fs18 1 (4.2%) \cell \row } @@ -729,13 +729,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 1 (4.2%) \cell \row } @@ -747,13 +747,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell \row } @@ -783,13 +783,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 5 (18.5%) \cell +\pard\intbl\qc\fs18 2 (8.3%) \cell \row } @@ -801,13 +801,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 2 (8.3%) \cell \row } @@ -819,12 +819,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -855,13 +855,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 2 (8.3%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 6 (22.2%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -873,13 +873,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (14.8%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -891,13 +891,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -928,66 +928,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2130 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3306 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2130 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3306 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2130 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3306 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 1 (4.2%) \cell \row } @@ -999,13 +945,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 1 (4.2%) \cell \row } @@ -1017,13 +963,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell \row } @@ -1054,12 +1000,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell \row } @@ -1071,13 +1017,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell \row } @@ -1107,12 +1053,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -1125,12 +1071,12 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5659 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6836 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8013 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell \pard\intbl\qc\fs18 0 \cell \row } diff --git a/tests/testthat/_snaps/tsfae22cpart2/tsfae22cpart2of4.rtf b/tests/testthat/_snaps/tsfae12c/tsfae12cpart1of4.rtf old mode 100755 new mode 100644 similarity index 78% rename from tests/testthat/_snaps/tsfae22cpart2/tsfae22cpart2of4.rtf rename to tests/testthat/_snaps/tsfae12c/tsfae12cpart1of4.rtf index 5ccf7d39..cb0c6373 --- a/tests/testthat/_snaps/tsfae22cpart2/tsfae22cpart2of4.rtf +++ b/tests/testthat/_snaps/tsfae12c/tsfae12cpart1of4.rtf @@ -7,7 +7,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3878 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5649 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7419 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE22cpart2of4:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE12cpart1of4:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -78,10 +78,10 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 44 \cell \row } @@ -106,10 +106,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 5 (100.0%) \cell -\pard\intbl\qc\fs18 15 (88.2%) \cell -\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 4 (100.0%) \cell +\pard\intbl\qc\fs18 16 (84.2%) \cell +\pard\intbl\qc\fs18 30 (68.2%) \cell \row } @@ -133,11 +133,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 5 (29.4%) \cell -\pard\intbl\qc\fs18 20 (39.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 3 (75.0%) \cell +\pard\intbl\qc\fs18 5 (26.3%) \cell +\pard\intbl\qc\fs18 17 (38.6%) \cell \row } @@ -147,11 +147,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 3 (17.6%) \cell -\pard\intbl\qc\fs18 10 (19.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 2 (50.0%) \cell +\pard\intbl\qc\fs18 4 (21.1%) \cell +\pard\intbl\qc\fs18 9 (20.5%) \cell \row } @@ -161,11 +161,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 7 (15.9%) \cell \row } @@ -175,11 +175,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 7 (13.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell \row } @@ -189,11 +189,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 5 (11.4%) \cell \row } @@ -203,11 +203,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell \row } @@ -217,11 +217,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell \row } @@ -231,11 +231,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell \row } @@ -245,11 +245,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 4 (80.0%) \cell -\pard\intbl\qc\fs18 7 (41.2%) \cell -\pard\intbl\qc\fs18 20 (39.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -259,11 +259,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 3 (60.0%) \cell -\pard\intbl\qc\fs18 5 (29.4%) \cell -\pard\intbl\qc\fs18 10 (19.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 6 (31.6%) \cell +\pard\intbl\qc\fs18 16 (36.4%) \cell \row } @@ -273,11 +273,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 3 (17.6%) \cell -\pard\intbl\qc\fs18 7 (13.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (21.1%) \cell +\pard\intbl\qc\fs18 9 (20.5%) \cell \row } @@ -287,11 +287,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 6 (13.6%) \cell \row } @@ -301,11 +301,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 6 (11.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 6 (13.6%) \cell \row } @@ -315,11 +315,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell \row } @@ -329,11 +329,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell \row } @@ -343,11 +343,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell \row } @@ -372,10 +372,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (23.5%) \cell -\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 5 (26.3%) \cell +\pard\intbl\qc\fs18 9 (20.5%) \cell \row } @@ -385,11 +385,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (23.5%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (26.3%) \cell +\pard\intbl\qc\fs18 4 (9.1%) \cell \row } @@ -399,11 +399,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell \row } @@ -413,11 +413,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (9.1%) \cell \row } @@ -427,11 +427,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell \row } @@ -456,10 +456,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell \row } @@ -469,11 +469,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell \row } @@ -483,11 +483,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell \row } @@ -497,11 +497,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell \row } @@ -511,11 +511,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell \row } @@ -540,10 +540,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 5 (11.4%) \cell \row } @@ -553,11 +553,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell \row } @@ -567,11 +567,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell \row } @@ -581,11 +581,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell \row } @@ -609,11 +609,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell \row } @@ -623,11 +623,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell \row } @@ -637,11 +637,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell \row } @@ -665,11 +665,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell \row } @@ -679,11 +679,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.9%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell \row } @@ -693,7 +693,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -722,38 +722,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell \row } @@ -763,25 +735,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2108 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell \row } @@ -791,11 +749,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell \row } @@ -820,10 +778,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell \row } @@ -833,11 +791,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell \row } @@ -861,7 +819,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -875,7 +833,7 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3878 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5649 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7419 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell diff --git a/tests/testthat/_snaps/tsfae12d/tsfae12dpart1of2.rtf b/tests/testthat/_snaps/tsfae12d/tsfae12dpart1of2.rtf new file mode 100644 index 00000000..cddf7b91 --- /dev/null +++ b/tests/testthat/_snaps/tsfae12d/tsfae12dpart1of2.rtf @@ -0,0 +1,1468 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3920 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5018 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7213 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8311 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10506 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11604 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE12dpart1of2:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3920 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5018 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7213 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8311 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10506 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11604 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx3920 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5018 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx6116 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7213 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx8311 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx9408 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx10506 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx11604 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=118 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5018 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8311 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11604 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Relationship \cell +\pard\intbl\qc\fs18 \keepn\trhdr Relationship \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Relationship \cell +\pard\intbl\qc\fs18 \keepn\trhdr Relationship \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Relationship \cell +\pard\intbl\qc\fs18 \keepn\trhdr Relationship \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3920 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5018 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7213 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8311 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10506 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11604 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\pard\intbl\qc\fs18 \keepn\trhdr Not Related \cell +\pard\intbl\qc\fs18 \keepn\trhdr Related \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\pard\intbl\qc\fs18 \keepn\trhdr Not Related \cell +\pard\intbl\qc\fs18 \keepn\trhdr Related \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\pard\intbl\qc\fs18 \keepn\trhdr Not Related \cell +\pard\intbl\qc\fs18 \keepn\trhdr Related \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell +\pard\intbl\qc\fs18 49 (73.1%) \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 48 (71.6%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 45 (88.2%) \cell +\pard\intbl\qc\fs18 95 (80.5%) \cell +\pard\intbl\qc\fs18 30 (25.4%) \cell +\pard\intbl\qc\fs18 93 (78.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 28 (23.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 (23.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 22 (32.8%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 21 (31.3%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 47 (39.8%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 46 (39.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 30 (25.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 27 (22.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 25 (21.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 16 (13.6%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3920 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5018 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7213 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8311 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10506 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11604 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3920 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5018 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7213 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8311 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10506 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11604 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3920 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5018 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7213 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8311 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10506 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11604 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae13/tsfae13.rtf b/tests/testthat/_snaps/tsfae13/tsfae13.rtf deleted file mode 100755 index 0af24576..00000000 --- a/tests/testthat/_snaps/tsfae13/tsfae13.rtf +++ /dev/null @@ -1,660 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2844 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3792 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4929 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5877 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9194 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE13:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2844 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3792 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4929 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5877 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9194 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, EAIR Per 100 SY \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subject years\super a\nosupersub \cell -\pard\intbl\qc\fs18 92.1 \cell -\pard\intbl\qc\fs18 126.5 \cell -\pard\intbl\qc\fs18 99.8 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 30.4 \cell -\pard\intbl\qc\fs18 13.9 \cell -\pard\intbl\qc\fs18 6.7 \cell -\pard\intbl\qc\fs18 23.77 (9.41, 38.12) \cell -\pard\intbl\qc\fs18 7.28 (-1.75, 16.31) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 18.4 \cell -\pard\intbl\qc\fs18 16.3 \cell -\pard\intbl\qc\fs18 4.2 \cell -\pard\intbl\qc\fs18 14.18 (3.39, 24.97) \cell -\pard\intbl\qc\fs18 12.09 (3.34, 20.84) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 16.0 \cell -\pard\intbl\qc\fs18 7.3 \cell -\pard\intbl\qc\fs18 6.6 \cell -\pard\intbl\qc\fs18 9.31 (-1.16, 19.79) \cell -\pard\intbl\qc\fs18 0.68 (-6.67, 8.02) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 13.1 \cell -\pard\intbl\qc\fs18 10.0 \cell -\pard\intbl\qc\fs18 2.1 \cell -\pard\intbl\qc\fs18 11.06 (2.43, 19.68) \cell -\pard\intbl\qc\fs18 7.96 (1.38, 14.55) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 10.7 \cell -\pard\intbl\qc\fs18 3.3 \cell -\pard\intbl\qc\fs18 2.1 \cell -\pard\intbl\qc\fs18 8.62 (0.67, 16.56) \cell -\pard\intbl\qc\fs18 1.19 (-3.11, 5.49) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 10.3 \cell -\pard\intbl\qc\fs18 6.2 \cell -\pard\intbl\qc\fs18 2.1 \cell -\pard\intbl\qc\fs18 8.21 (0.55, 15.87) \cell -\pard\intbl\qc\fs18 4.11 (-1.27, 9.50) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 9.1 \cell -\pard\intbl\qc\fs18 6.9 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 9.08 (2.35, 15.80) \cell -\pard\intbl\qc\fs18 6.88 (2.11, 11.65) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 8.7 \cell -\pard\intbl\qc\fs18 3.3 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 8.66 (2.24, 15.07) \cell -\pard\intbl\qc\fs18 3.35 (0.07, 6.63) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 6.2 \cell -\pard\intbl\qc\fs18 2.5 \cell -\pard\intbl\qc\fs18 2.1 \cell -\pard\intbl\qc\fs18 4.12 (-2.00, 10.24) \cell -\pard\intbl\qc\fs18 0.40 (-3.58, 4.38) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 6.1 \cell -\pard\intbl\qc\fs18 1.6 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 6.12 (0.76, 11.48) \cell -\pard\intbl\qc\fs18 1.60 (-0.62, 3.81) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 RASH \cell -\pard\intbl\qc\fs18 6.0 \cell -\pard\intbl\qc\fs18 8.1 \cell -\pard\intbl\qc\fs18 4.3 \cell -\pard\intbl\qc\fs18 1.70 (-4.99, 8.39) \cell -\pard\intbl\qc\fs18 3.86 (-2.90, 10.61) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5.9 \cell -\pard\intbl\qc\fs18 4.3 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 5.93 (0.73, 11.12) \cell -\pard\intbl\qc\fs18 4.30 (0.53, 8.07) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5.8 \cell -\pard\intbl\qc\fs18 1.7 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 5.84 (0.72, 10.97) \cell -\pard\intbl\qc\fs18 1.65 (-0.64, 3.94) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4.7 \cell -\pard\intbl\qc\fs18 3.3 \cell -\pard\intbl\qc\fs18 3.1 \cell -\pard\intbl\qc\fs18 1.67 (-4.12, 7.47) \cell -\pard\intbl\qc\fs18 0.28 (-4.49, 5.05) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4.7 \cell -\pard\intbl\qc\fs18 6.0 \cell -\pard\intbl\qc\fs18 5.5 \cell -\pard\intbl\qc\fs18 -0.77 (-7.42, 5.89) \cell -\pard\intbl\qc\fs18 0.57 (-5.99, 7.13) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4.6 \cell -\pard\intbl\qc\fs18 3.3 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 4.58 (0.09, 9.07) \cell -\pard\intbl\qc\fs18 3.31 (0.07, 6.55) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3.5 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 2.0 \cell -\pard\intbl\qc\fs18 1.44 (-3.40, 6.28) \cell -\pard\intbl\qc\fs18 -2.04 (-4.86, 0.79) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3.4 \cell -\pard\intbl\qc\fs18 0.8 \cell -\pard\intbl\qc\fs18 3.1 \cell -\pard\intbl\qc\fs18 0.30 (-4.94, 5.55) \cell -\pard\intbl\qc\fs18 -2.33 (-6.19, 1.53) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3.4 \cell -\pard\intbl\qc\fs18 3.4 \cell -\pard\intbl\qc\fs18 1.0 \cell -\pard\intbl\qc\fs18 2.38 (-1.94, 6.71) \cell -\pard\intbl\qc\fs18 2.35 (-1.49, 6.20) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3.4 \cell -\pard\intbl\qc\fs18 2.5 \cell -\pard\intbl\qc\fs18 2.1 \cell -\pard\intbl\qc\fs18 1.24 (-3.59, 6.07) \cell -\pard\intbl\qc\fs18 0.36 (-3.73, 4.44) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2.3 \cell -\pard\intbl\qc\fs18 0.8 \cell -\pard\intbl\qc\fs18 1.0 \cell -\pard\intbl\qc\fs18 1.28 (-2.45, 5.02) \cell -\pard\intbl\qc\fs18 -0.20 (-2.72, 2.33) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2.3 \cell -\pard\intbl\qc\fs18 2.4 \cell -\pard\intbl\qc\fs18 3.1 \cell -\pard\intbl\qc\fs18 -0.82 (-5.55, 3.90) \cell -\pard\intbl\qc\fs18 -0.66 (-5.13, 3.80) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2.3 \cell -\pard\intbl\qc\fs18 0.8 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 2.27 (-0.87, 5.40) \cell -\pard\intbl\qc\fs18 0.80 (-0.77, 2.36) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2.3 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 5.3 \cell -\pard\intbl\qc\fs18 -3.01 (-8.59, 2.58) \cell -\pard\intbl\qc\fs18 -5.27 (-9.89, -0.65) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1.1 \cell -\pard\intbl\qc\fs18 1.6 \cell -\pard\intbl\qc\fs18 1.0 \cell -\pard\intbl\qc\fs18 0.09 (-2.89, 3.07) \cell -\pard\intbl\qc\fs18 0.58 (-2.43, 3.60) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1.1 \cell -\pard\intbl\qc\fs18 0.8 \cell -\pard\intbl\qc\fs18 1.0 \cell -\pard\intbl\qc\fs18 0.10 (-2.86, 3.06) \cell -\pard\intbl\qc\fs18 -0.23 (-2.76, 2.30) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1.1 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 1.11 (-1.07, 3.30) \cell -\pard\intbl\qc\fs18 0.00 (0.00, 0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1.1 \cell -\pard\intbl\qc\fs18 0.8 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 1.10 (-1.06, 3.26) \cell -\pard\intbl\qc\fs18 0.80 (-0.77, 2.37) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1.1 \cell -\pard\intbl\qc\fs18 2.4 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 1.09 (-1.05, 3.24) \cell -\pard\intbl\qc\fs18 2.42 (-0.32, 5.17) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1.1 \cell -\pard\intbl\qc\fs18 1.6 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 1.09 (-1.05, 3.23) \cell -\pard\intbl\qc\fs18 1.63 (-0.63, 3.90) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1.1 \cell -\pard\intbl\qc\fs18 1.6 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 1.09 (-1.05, 3.23) \cell -\pard\intbl\qc\fs18 1.62 (-0.62, 3.86) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 1.6 \cell -\pard\intbl\qc\fs18 1.0 \cell -\pard\intbl\qc\fs18 -1.03 (-3.04, 0.98) \cell -\pard\intbl\qc\fs18 0.58 (-2.42, 3.57) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2844 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3792 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4929 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5877 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9194 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.8 \cell -\pard\intbl\qc\fs18 0.0 \cell -\pard\intbl\qc\fs18 0.00 (0.00, 0.00) \cell -\pard\intbl\qc\fs18 0.81 (-0.78, 2.39) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2844 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3792 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4929 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5877 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9194 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2844 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3792 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4929 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5877 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9194 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsiex11/tsiex11.rtf b/tests/testthat/_snaps/tsfae13a/tsfae13a.rtf old mode 100755 new mode 100644 similarity index 73% rename from tests/testthat/_snaps/tsiex11/tsiex11.rtf rename to tests/testthat/_snaps/tsfae13a/tsfae13a.rtf index 2b384ad4..6ee2e944 --- a/tests/testthat/_snaps/tsiex11/tsiex11.rtf +++ b/tests/testthat/_snaps/tsfae13a/tsfae13a.rtf @@ -7,7 +7,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX11:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE13a:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,7 +21,7 @@ \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4444 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6026 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7608 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -35,9 +35,9 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Time Relative to Infusion \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row @@ -49,11 +49,11 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Modification, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } @@ -63,11 +63,11 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Overall \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related SAE \cell +\pard\intbl\qc\fs18 39 (58.2%) \cell +\pard\intbl\qc\fs18 39 (76.5%) \cell +\pard\intbl\qc\fs18 78 (66.1%) \cell +\pard\intbl\qc\fs18 22 (34.4%) \cell \row } @@ -77,7 +77,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Prior to infusion \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -91,11 +91,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } @@ -105,11 +105,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Infusion delayed \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 20 (27.4%) \cell -\pard\intbl\qc\fs18 32 (25.4%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell \row } @@ -119,10 +119,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Other \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -133,11 +133,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Erythema \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell \row } @@ -147,11 +147,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Study agent permanently discontinued \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 16 (21.9%) \cell -\pard\intbl\qc\fs18 29 (23.0%) \cell -\pard\intbl\qc\fs18 24 (40.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Rash \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \row } @@ -161,10 +161,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Adverse Event \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -175,11 +175,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } @@ -189,11 +189,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 During infusion \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \row } @@ -203,11 +203,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -217,11 +217,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Infusion interrupted \cell -\pard\intbl\qc\fs18 19 (35.8%) \cell -\pard\intbl\qc\fs18 24 (32.9%) \cell -\pard\intbl\qc\fs18 43 (34.1%) \cell -\pard\intbl\qc\fs18 19 (32.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nausea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -231,10 +231,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Adverse Event \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -245,11 +245,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -259,11 +259,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Week 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -273,11 +273,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Prior to infusion \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -287,11 +287,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 52 \cell -\pard\intbl\qc\fs18 105 \cell -\pard\intbl\qc\fs18 56 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \row } @@ -301,11 +301,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Study agent permanently discontinued \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 3 (5.8%) \cell -\pard\intbl\qc\fs18 12 (11.4%) \cell -\pard\intbl\qc\fs18 9 (16.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -315,10 +315,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Adverse Event \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blister \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -329,25 +329,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 During infusion \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -357,11 +343,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 52 \cell -\pard\intbl\qc\fs18 105 \cell -\pard\intbl\qc\fs18 56 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -371,11 +357,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Infusion interrupted \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 12 (23.1%) \cell -\pard\intbl\qc\fs18 24 (22.9%) \cell -\pard\intbl\qc\fs18 11 (19.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } @@ -385,10 +371,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Adverse Event \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -399,11 +385,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -413,11 +399,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Week 24 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -427,11 +413,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Prior to infusion \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -441,11 +427,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 15 \cell -\pard\intbl\qc\fs18 35 \cell -\pard\intbl\qc\fs18 40 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cough \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -455,11 +441,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Infusion delayed \cell -\pard\intbl\qc\fs18 5 (25.0%) \cell -\pard\intbl\qc\fs18 2 (13.3%) \cell -\pard\intbl\qc\fs18 7 (20.0%) \cell -\pard\intbl\qc\fs18 5 (12.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -469,11 +455,11 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Other \cell -\pard\intbl\qc\fs18 1 (5.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } diff --git a/tests/testthat/_snaps/tsfae23b/tsfae23b.rtf b/tests/testthat/_snaps/tsfae13b/tsfae13b.rtf old mode 100755 new mode 100644 similarity index 60% rename from tests/testthat/_snaps/tsfae23b/tsfae23b.rtf rename to tests/testthat/_snaps/tsfae13b/tsfae13b.rtf index c8b40ed4..0d7ca372 --- a/tests/testthat/_snaps/tsfae23b/tsfae23b.rtf +++ b/tests/testthat/_snaps/tsfae13b/tsfae13b.rtf @@ -4,10 +4,10 @@ { \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2797 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4395 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5993 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7591 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE23b:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3796 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4795 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5793 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE13b:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -18,9 +18,9 @@ { \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2797 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4395 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5993 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7591 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3796 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4795 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5793 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -32,12 +32,12 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2797 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5993 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3796 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4795 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5793 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row @@ -46,37 +46,65 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2797 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5993 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7591 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3796 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4795 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5793 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2797 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3796 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4795 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5793 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related fatal AE \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2797 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3796 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4795 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5793 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2797 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4395 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5993 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7591 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 - No Data To Display - \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2797 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3796 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4795 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5793 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2797 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4395 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5993 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7591 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3796 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4795 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5793 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -88,9 +116,9 @@ { \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2797 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5993 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3796 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4795 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5793 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae13c/tsfae13c.rtf b/tests/testthat/_snaps/tsfae13c/tsfae13c.rtf new file mode 100644 index 00000000..fa05f531 --- /dev/null +++ b/tests/testthat/_snaps/tsfae13c/tsfae13c.rtf @@ -0,0 +1,368 @@ +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4479 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6101 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7722 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE13c:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2858 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4479 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6101 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7722 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related AE leading to discontinuation \cell +\pard\intbl\qc\fs18 16 (23.9%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 33 (28.0%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Erythema \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Headache \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blister \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Rash \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Syncope \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4479 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6101 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7722 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4479 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6101 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7722 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4479 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6101 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7722 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsiex08/tsiex08.rtf b/tests/testthat/_snaps/tsfae13d/tsfae13d.rtf old mode 100755 new mode 100644 similarity index 65% rename from tests/testthat/_snaps/tsiex08/tsiex08.rtf rename to tests/testthat/_snaps/tsfae13d/tsfae13d.rtf index 15d1a983..fc19812b --- a/tests/testthat/_snaps/tsiex08/tsiex08.rtf +++ b/tests/testthat/_snaps/tsfae13d/tsfae13d.rtf @@ -7,7 +7,7 @@ \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX08:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE13d:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -35,9 +35,9 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row @@ -49,11 +49,11 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Dose Modification, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } @@ -63,11 +63,11 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Overall \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related non-serious AE \cell +\pard\intbl\qc\fs18 43 (64.2%) \cell +\pard\intbl\qc\fs18 37 (72.5%) \cell +\pard\intbl\qc\fs18 80 (67.8%) \cell +\pard\intbl\qc\fs18 27 (42.2%) \cell \row } @@ -77,11 +77,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose not administered \cell -\pard\intbl\qc\fs18 47 (88.7%) \cell -\pard\intbl\qc\fs18 52 (71.2%) \cell -\pard\intbl\qc\fs18 99 (78.6%) \cell -\pard\intbl\qc\fs18 49 (83.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -91,11 +91,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse Event \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell \row } @@ -105,11 +105,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } @@ -119,11 +119,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose adjusted \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -133,10 +133,66 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse Event \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Erythema \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -147,10 +203,38 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -161,11 +245,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -175,11 +259,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Baseline \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -189,11 +273,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose not administered \cell -\pard\intbl\qc\fs18 28 (52.8%) \cell -\pard\intbl\qc\fs18 36 (49.3%) \cell -\pard\intbl\qc\fs18 64 (50.8%) \cell -\pard\intbl\qc\fs18 24 (40.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -203,11 +287,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Syncope \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -217,11 +301,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Week 2 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 52 \cell -\pard\intbl\qc\fs18 105 \cell -\pard\intbl\qc\fs18 56 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blister \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -231,11 +315,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose not administered \cell -\pard\intbl\qc\fs18 28 (52.8%) \cell -\pard\intbl\qc\fs18 28 (53.8%) \cell -\pard\intbl\qc\fs18 56 (53.3%) \cell -\pard\intbl\qc\fs18 30 (53.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell \row } @@ -245,10 +329,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse Event \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Headache \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -259,11 +343,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose adjusted \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Rash \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } @@ -273,10 +357,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse Event \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -287,11 +371,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -301,11 +385,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Week 24 \cell -\pard\intbl\qc\fs18 20 \cell -\pard\intbl\qc\fs18 15 \cell -\pard\intbl\qc\fs18 35 \cell -\pard\intbl\qc\fs18 40 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Back pain \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -315,11 +399,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose not administered \cell -\pard\intbl\qc\fs18 9 (45.0%) \cell -\pard\intbl\qc\fs18 8 (53.3%) \cell -\pard\intbl\qc\fs18 17 (48.6%) \cell -\pard\intbl\qc\fs18 25 (62.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -329,10 +413,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse Event \cell -\pard\intbl\qc\fs18 1 (5.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cough \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -343,11 +427,25 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 1 (5.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nasal congestion \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -357,10 +455,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose adjusted \cell -\pard\intbl\qc\fs18 1 (5.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -371,11 +469,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse Event \cell -\pard\intbl\qc\fs18 1 (5.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } @@ -385,11 +483,11 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 1 (5.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } diff --git a/tests/testthat/_snaps/tsfae14/tsfae14.rtf b/tests/testthat/_snaps/tsfae14/tsfae14.rtf deleted file mode 100755 index 0d5eb128..00000000 --- a/tests/testthat/_snaps/tsfae14/tsfae14.rtf +++ /dev/null @@ -1,1678 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5675 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE14:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2838 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5675 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7094 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8513 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10607 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Organ System\super a\nosupersub \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 OCMQ (Narrow), n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 34 (64.2%) \cell -\pard\intbl\qc\fs18 28 (38.4%) \cell -\pard\intbl\qc\fs18 62 (49.2%) \cell -\pard\intbl\qc\fs18 11 (18.6%) \cell -\pard\intbl\qc\fs18 45.5 (29.2, 61.8) \cell -\pard\intbl\qc\fs18 19.7 (4.8, 34.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell -\pard\intbl\qc\fs18 24 (45.3%) \cell -\pard\intbl\qc\fs18 21 (28.8%) \cell -\pard\intbl\qc\fs18 45 (35.7%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 35.1 (19.7, 50.6) \cell -\pard\intbl\qc\fs18 18.6 (5.7, 31.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell -\pard\intbl\qc\fs18 16 (30.2%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 30 (23.8%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 21.7 (7.5, 36.0) \cell -\pard\intbl\qc\fs18 10.7 (-0.8, 22.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 12.1 (-0.2, 24.4) \cell -\pard\intbl\qc\fs18 4.2 (-5.4, 13.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Urticaria \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 16 (21.9%) \cell -\pard\intbl\qc\fs18 28 (22.2%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 10.8 (-3.2, 24.7) \cell -\pard\intbl\qc\fs18 10.1 (-2.5, 22.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Local Administration Reaction \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2.7 (-7.5, 12.8) \cell -\pard\intbl\qc\fs18 0.1 (-8.6, 8.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 5.5 (0.3, 10.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5.9 (-2.0, 13.7) \cell -\pard\intbl\qc\fs18 2.4 (-3.2, 8.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fall \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Peripheral Edema \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pyrexia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 7.9 (-1.8, 17.6) \cell -\pard\intbl\qc\fs18 7.6 (-1.0, 16.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 2.4 (-3.2, 8.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Confusional State \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Stroke and TIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Paresthesia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Seizure \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 2.8 (-8.3, 13.9) \cell -\pard\intbl\qc\fs18 1.1 (-8.7, 10.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arrhythmia \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 1.8 (-6.3, 9.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acute Coronary Syndrome \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial Infarction \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial Ischemia \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cardiac Conduction Disturbance \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 -0.7 (-6.6, 5.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Tachycardia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 10.0 (-1.1, 21.2) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhea \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal Pain \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dyspepsia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Constipation \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 -2.4 (-13.8, 9.0) \cell -\pard\intbl\qc\fs18 -5.0 (-15.1, 5.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 -0.9 (-11.0, 9.1) \cell -\pard\intbl\qc\fs18 -4.4 (-12.8, 4.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Bacterial Infection \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pneumonia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Viral Infection \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0.6 (-7.8, 8.9) \cell -\pard\intbl\qc\fs18 3.1 (-5.3, 11.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Thrombosis \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Thrombosis Arterial \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hemorrhage \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 2.4 (-3.2, 8.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypotension \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 -4.9 (-12.3, 2.5) \cell -\pard\intbl\qc\fs18 -1.3 (-9.6, 7.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Study Agent Abuse Potential \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 2.4 (-3.2, 8.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Insomnia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Irritability \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Psychosis \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5.9 (-2.0, 13.7) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back Pain \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fracture \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Osteoporosis \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Reproductive system and breast disorders \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4.0 (-3.1, 11.0) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sexual Dysfunction \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abnormal Uterine Bleeding \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erectile Dysfunction \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Excessive Menstrual Bleeding \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ear and labyrinth disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vertigo \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Endocrine disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperglycemia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutrition disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lipid Disorder \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Immune system disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypersensitivity \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Renal and urinary disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5675 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10607 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Renal & Urinary Tract Infection \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5675 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7094 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8513 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10607 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4257 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5675 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7094 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8513 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10607 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae15/tsfae15.rtf b/tests/testthat/_snaps/tsfae15/tsfae15.rtf deleted file mode 100755 index 1fd47c76..00000000 --- a/tests/testthat/_snaps/tsfae15/tsfae15.rtf +++ /dev/null @@ -1,904 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4210 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5444 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6968 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8202 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10451 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE15:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2831 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4210 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5444 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6968 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8202 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10451 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Organ System\super a\nosupersub \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 OCMQ (Narrow), n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 10.2 (-1.8, 22.2) \cell -\pard\intbl\qc\fs18 1.4 (-7.6, 10.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 7.7 (-0.8, 16.3) \cell -\pard\intbl\qc\fs18 5.2 (-1.5, 11.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4.0 (-3.1, 11.0) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Local Administration Reaction \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Decreased Appetite \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Peripheral Edema \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5.9 (-2.0, 13.7) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Confusional State \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 -3.0 (-11.2, 5.2) \cell -\pard\intbl\qc\fs18 -5.4 (-12.4, 1.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Bacterial Infection \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hemorrhage \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Thrombosis \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Thrombosis Arterial \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acute Coronary Syndrome \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial Infarction \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial Ischemia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Palpitations \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhea \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dyspnea \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Immune system disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypersensitivity \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Renal and urinary disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4210 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5444 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6968 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8202 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10451 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Renal & Urinary Tract Infection \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4210 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5444 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6968 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8202 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10451 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4210 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5444 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6968 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8202 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10451 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae16part1/tsfae16part1of2.rtf b/tests/testthat/_snaps/tsfae16part1/tsfae16part1of2.rtf deleted file mode 100755 index 2cd3cca4..00000000 --- a/tests/testthat/_snaps/tsfae16part1/tsfae16part1of2.rtf +++ /dev/null @@ -1,2688 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3940 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5029 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6118 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7828 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9435 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10524 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11613 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE16part1of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2852 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx3940 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx5029 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx6118 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx7828 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx9435 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx10524 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx11613 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Narrow OCMQs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Narrow OCMQs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Narrow OCMQs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Narrow OCMQs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Narrow OCMQs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Broad OCMQs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Broad OCMQs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Broad OCMQs \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx3940 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7828 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx9435 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx10524 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Organ System Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 OCMQ, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Immune system disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 42 (79.2%) \cell -\pard\intbl\qc\fs18 38 (52.1%) \cell -\pard\intbl\qc\fs18 19 (32.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypersensitivity \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 41 (77.4%) \cell -\pard\intbl\qc\fs18 38 (52.1%) \cell -\pard\intbl\qc\fs18 19 (32.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Angioedema \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 39 (73.6%) \cell -\pard\intbl\qc\fs18 39 (53.4%) \cell -\pard\intbl\qc\fs18 17 (28.8%) \cell -\pard\intbl\qc\fs18 44.8 (28.2, 61.3) \cell -\pard\intbl\qc\fs18 24.6 (8.3, 40.9) \cell -\pard\intbl\qc\fs18 24 (45.3%) \cell -\pard\intbl\qc\fs18 22 (30.1%) \cell -\pard\intbl\qc\fs18 12 (20.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell -\pard\intbl\qc\fs18 14 (26.4%) \cell -\pard\intbl\qc\fs18 17 (23.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 19.6 (6.1, 33.1) \cell -\pard\intbl\qc\fs18 16.5 (4.9, 28.1) \cell -\pard\intbl\qc\fs18 16 (30.2%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 8 (13.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Urticaria \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell -\pard\intbl\qc\fs18 21 (39.6%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 8 (13.6%) \cell -\pard\intbl\qc\fs18 26.1 (10.3, 41.9) \cell -\pard\intbl\qc\fs18 11.1 (-2.1, 24.3) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell -\pard\intbl\qc\fs18 36 (67.9%) \cell -\pard\intbl\qc\fs18 33 (45.2%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\pard\intbl\qc\fs18 51.0 (35.2, 66.8) \cell -\pard\intbl\qc\fs18 28.3 (13.4, 43.2) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alopecia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 14.2 (0.8, 27.5) \cell -\pard\intbl\qc\fs18 10.7 (-0.8, 22.2) \cell -\pard\intbl\qc\fs18 15 (28.3%) \cell -\pard\intbl\qc\fs18 15 (20.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 4.1 (-0.4, 8.7) \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Confusional State \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dysgeusia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6.0 (-3.1, 15.2) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Paresthesia \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Seizure \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Stroke and TIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 12.3 (-0.7, 25.3) \cell -\pard\intbl\qc\fs18 3.9 (-6.5, 14.2) \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dyspepsia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal Pain \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Constipation \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhea \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 22 (30.1%) \cell -\pard\intbl\qc\fs18 12 (20.3%) \cell -\pard\intbl\qc\fs18 17.4 (0.8, 34.0) \cell -\pard\intbl\qc\fs18 9.8 (-4.9, 24.5) \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 15 (20.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fall \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 11.5 (1.8, 21.2) \cell -\pard\intbl\qc\fs18 6.5 (-0.6, 13.6) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pyrexia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 -0.7 (-6.6, 5.3) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Decreased Appetite \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 10 (13.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 17.0 (6.9, 27.1) \cell -\pard\intbl\qc\fs18 13.7 (5.8, 21.6) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Local Administration Reaction \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 4.7 (-6.8, 16.3) \cell -\pard\intbl\qc\fs18 3.9 (-6.5, 14.2) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Peripheral Edema \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Volume Depletion \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 8 (13.6%) \cell -\pard\intbl\qc\fs18 7.2 (-6.8, 21.2) \cell -\pard\intbl\qc\fs18 2.9 (-9.3, 15.1) \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arrhythmia \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 11.9 (0.3, 23.5) \cell -\pard\intbl\qc\fs18 7.2 (-2.2, 16.6) \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Heart Failure \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial Ischemia \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0.6 (-7.8, 8.9) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acute Coronary Syndrome \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0.6 (-7.8, 8.9) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cardiac Conduction Disturbance \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial Infarction \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0.6 (-7.8, 8.9) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Palpitations \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systemic Hypertension \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Tachycardia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ear and labyrinth disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vertigo \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2.7 (-7.5, 12.8) \cell -\pard\intbl\qc\fs18 2.8 (-6.5, 12.1) \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Psychosis \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Study Agent Abuse Potential \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 2.4 (-3.2, 8.0) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Depression \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Insomnia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Irritability \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 2.4 (-3.2, 8.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Mania \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Parasomnia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\pard\intbl\qc\fs18 -1.9 (-15.4, 11.7) \cell -\pard\intbl\qc\fs18 -8.7 (-20.2, 2.7) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Viral Infection \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pneumonia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Bacterial Infection \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 -0.5 (-12.4, 11.3) \cell -\pard\intbl\qc\fs18 -7.8 (-17.2, 1.7) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6.0 (-3.1, 15.2) \cell -\pard\intbl\qc\fs18 -0.7 (-6.6, 5.3) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthritis \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back Pain \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4.0 (-3.1, 11.0) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fracture \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Muscle Injury \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myalgia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Osteoporosis \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Renal and urinary disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Urinary Retention \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Renal & Urinary Tract Infection \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Endocrine disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperglycemia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Eye disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Glaucoma \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hepatobiliary disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hepatic Injury \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutrition disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cachexia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lipid Disorder \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Neoplasms benign, malignant and unspecified (incl cysts and polyps) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Malignancy \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Reproductive system and breast disorders \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2.3 (-5.5, 10.0) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abnormal Uterine Bleeding \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erectile Dysfunction \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Excessive Menstrual Bleeding \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sexual Dysfunction \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.4 (-6.5, 7.3) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5.9 (-2.0, 13.7) \cell -\pard\intbl\qc\fs18 5.2 (-1.5, 11.8) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Bronchospasm \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5.9 (-2.0, 13.7) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dyspnea \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Respiratory Failure \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 6.4 (-4.7, 17.6) \cell -\pard\intbl\qc\fs18 4.2 (-5.4, 13.8) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hemorrhage \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4.0 (-3.1, 11.0) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypotension \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 -2.0 (-7.4, 3.3) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Thrombosis \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3940 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5029 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6118 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9435 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10524 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11613 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Thrombosis Arterial \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3940 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5029 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6118 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9435 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10524 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11613 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3940 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5029 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6118 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9435 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10524 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11613 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae16part2/tsfae16part2of2.rtf b/tests/testthat/_snaps/tsfae16part2/tsfae16part2of2.rtf deleted file mode 100755 index 17da7268..00000000 --- a/tests/testthat/_snaps/tsfae16part2/tsfae16part2of2.rtf +++ /dev/null @@ -1,1224 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2774 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7592 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE16part2of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2774 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7592 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Broad OCMQs \cell -\pard\intbl\qc\fs18 \keepn\trhdr Broad OCMQs \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7592 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Organ System Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 OCMQ, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Immune system disorders \cell -\pard\intbl\qc\fs18 47.0 (30.9, 63.2) \cell -\pard\intbl\qc\fs18 19.9 (3.3, 36.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypersensitivity \cell -\pard\intbl\qc\fs18 45.2 (28.8, 61.6) \cell -\pard\intbl\qc\fs18 19.9 (3.3, 36.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Angioedema \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 24.9 (8.1, 41.8) \cell -\pard\intbl\qc\fs18 9.8 (-4.9, 24.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell -\pard\intbl\qc\fs18 16.6 (1.5, 31.8) \cell -\pard\intbl\qc\fs18 2.9 (-9.3, 15.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Urticaria \cell -\pard\intbl\qc\fs18 8.5 (-3.8, 20.9) \cell -\pard\intbl\qc\fs18 6.6 (-4.3, 17.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell -\pard\intbl\qc\fs18 2.5 (-6.6, 11.5) \cell -\pard\intbl\qc\fs18 0.4 (-7.3, 8.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alopecia \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 23.2 (9.9, 36.6) \cell -\pard\intbl\qc\fs18 15.5 (4.6, 26.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell -\pard\intbl\qc\fs18 11.7 (1.0, 22.4) \cell -\pard\intbl\qc\fs18 7.6 (-1.0, 16.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 6.8 (1.1, 12.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Confusional State \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 2.4 (-3.2, 8.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dysgeusia \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Paresthesia \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Seizure \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Stroke and TIA \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 20.9 (9.2, 32.7) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dyspepsia \cell -\pard\intbl\qc\fs18 7.7 (-0.8, 16.3) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell -\pard\intbl\qc\fs18 9.4 (1.6, 17.3) \cell -\pard\intbl\qc\fs18 2.7 (-1.0, 6.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell -\pard\intbl\qc\fs18 7.7 (-0.8, 16.3) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal Pain \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Constipation \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhea \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 15.7 (3.4, 27.9) \cell -\pard\intbl\qc\fs18 15.5 (4.6, 26.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fall \cell -\pard\intbl\qc\fs18 15.5 (4.0, 27.0) \cell -\pard\intbl\qc\fs18 13.0 (3.4, 22.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pyrexia \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Decreased Appetite \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Local Administration Reaction \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Peripheral Edema \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Volume Depletion \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 7.0 (-6.4, 20.4) \cell -\pard\intbl\qc\fs18 7.3 (-4.9, 19.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arrhythmia \cell -\pard\intbl\qc\fs18 17.0 (6.9, 27.1) \cell -\pard\intbl\qc\fs18 15.1 (6.9, 23.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Heart Failure \cell -\pard\intbl\qc\fs18 -1.5 (-7.4, 4.4) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial Ischemia \cell -\pard\intbl\qc\fs18 -4.9 (-12.3, 2.5) \cell -\pard\intbl\qc\fs18 -2.7 (-10.5, 5.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acute Coronary Syndrome \cell -\pard\intbl\qc\fs18 -6.8 (-13.2, -0.4) \cell -\pard\intbl\qc\fs18 -5.4 (-12.4, 1.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cardiac Conduction Disturbance \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial Infarction \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Palpitations \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systemic Hypertension \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Tachycardia \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ear and labyrinth disorders \cell -\pard\intbl\qc\fs18 15.1 (5.5, 24.7) \cell -\pard\intbl\qc\fs18 12.3 (4.8, 19.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vertigo \cell -\pard\intbl\qc\fs18 15.1 (5.5, 24.7) \cell -\pard\intbl\qc\fs18 12.3 (4.8, 19.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 7.9 (-1.8, 17.6) \cell -\pard\intbl\qc\fs18 2.1 (-4.9, 9.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Psychosis \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Study Agent Abuse Potential \cell -\pard\intbl\qc\fs18 4.0 (-3.1, 11.0) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 3.8 (-2.4, 10.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Depression \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Insomnia \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Irritability \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Mania \cell -\pard\intbl\qc\fs18 -3.4 (-8.0, 1.2) \cell -\pard\intbl\qc\fs18 0.7 (-5.8, 7.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Parasomnia \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 -9.4 (-21.3, 2.5) \cell -\pard\intbl\qc\fs18 -14.2 (-24.5, -3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Viral Infection \cell -\pard\intbl\qc\fs18 -4.5 (-14.4, 5.4) \cell -\pard\intbl\qc\fs18 -8.8 (-17.0, -0.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pneumonia \cell -\pard\intbl\qc\fs18 2.1 (-4.0, 8.2) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Bacterial Infection \cell -\pard\intbl\qc\fs18 -3.2 (-9.9, 3.5) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 1.0 (-3.9, 6.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthritis \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back Pain \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fracture \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Muscle Injury \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myalgia \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Osteoporosis \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Renal and urinary disorders \cell -\pard\intbl\qc\fs18 -3.2 (-9.9, 3.5) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Urinary Retention \cell -\pard\intbl\qc\fs18 -3.2 (-9.9, 3.5) \cell -\pard\intbl\qc\fs18 -1.0 (-8.2, 6.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Renal & Urinary Tract Infection \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Endocrine disorders \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperglycemia \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Eye disorders \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Glaucoma \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hepatobiliary disorders \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hepatic Injury \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutrition disorders \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cachexia \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lipid Disorder \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Neoplasms benign, malignant and unspecified (incl cysts and polyps) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Malignancy \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Reproductive system and breast disorders \cell -\pard\intbl\qc\fs18 -5.1 (-10.7, 0.5) \cell -\pard\intbl\qc\fs18 -3.7 (-9.9, 2.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abnormal Uterine Bleeding \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erectile Dysfunction \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Excessive Menstrual Bleeding \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sexual Dysfunction \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Bronchospasm \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dyspnea \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Respiratory Failure \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hemorrhage \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypotension \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Thrombosis \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2774 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7592 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Thrombosis Arterial \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2774 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7592 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2774 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7592 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae17a/tsfae17a.rtf b/tests/testthat/_snaps/tsfae17a/tsfae17a.rtf deleted file mode 100755 index 0c653fda..00000000 --- a/tests/testthat/_snaps/tsfae17a/tsfae17a.rtf +++ /dev/null @@ -1,958 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE17a:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6821 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8154 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Organ System\super a\nosupersub \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 OCMQ (Narrow) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ear and labyrinth disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vertigo \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 VERTIGO \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Endocrine disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperglycemia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 BLOOD GLUCOSE INCREASED \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Bacterial Infection \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CELLULITIS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutrition disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lipid Disorder \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 BLOOD CHOLESTEROL INCREASED \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back Pain \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 FLANK PAIN \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hemorrhage \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 EPISTAXIS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cardiac Conduction Disturbance \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ATRIOVENTRICULAR BLOCK SECOND DEGREE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Immune system disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypersensitivity \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DRUG ERUPTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Renal and urinary disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Renal & Urinary Tract Infection \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 URINARY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae17b/tsfae17b.rtf b/tests/testthat/_snaps/tsfae17b/tsfae17b.rtf deleted file mode 100755 index 11059813..00000000 --- a/tests/testthat/_snaps/tsfae17b/tsfae17b.rtf +++ /dev/null @@ -1,670 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE17b:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6821 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8154 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Organ System\super a\nosupersub \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 OCMQ (Narrow) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acute Coronary Syndrome \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 LISTLESS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dyspnea \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DYSPNOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhea \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Immune system disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypersensitivity \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DRUG ERUPTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Renal and urinary disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Renal & Urinary Tract Infection \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 URINARY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae17c/tsfae17c.rtf b/tests/testthat/_snaps/tsfae17c/tsfae17c.rtf deleted file mode 100755 index 36a7f235..00000000 --- a/tests/testthat/_snaps/tsfae17c/tsfae17c.rtf +++ /dev/null @@ -1,1102 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE17c:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6821 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8154 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Organ System\super a\nosupersub \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 OCMQ (Narrow) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ear and labyrinth disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vertigo \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 VERTIGO \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Endocrine disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperglycemia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 BLOOD GLUCOSE INCREASED \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutrition disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lipid Disorder \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 BLOOD CHOLESTEROL INCREASED \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Neoplasms benign, malignant and unspecified (incl cysts and polyps) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Malignancy \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 COLON CANCER \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Confusional State \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 CONFUSIONAL STATE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Irritability \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 AGITATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dyspnea \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DYSPNOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hemorrhage \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 EPISTAXIS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cardiac Conduction Disturbance \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ATRIOVENTRICULAR BLOCK SECOND DEGREE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Immune system disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypersensitivity \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 EYE ALLERGY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Renal and urinary disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Renal & Urinary Tract Infection \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 URINARY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae17d/tsfae17d.rtf b/tests/testthat/_snaps/tsfae17d/tsfae17d.rtf deleted file mode 100755 index f1d1ce2d..00000000 --- a/tests/testthat/_snaps/tsfae17d/tsfae17d.rtf +++ /dev/null @@ -1,1030 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE17d:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6821 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8154 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Organ System\super a\nosupersub \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 OCMQ (Broad) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial Infarction \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 SUDDEN DEATH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ear and labyrinth disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vertigo \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fall \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutrition disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cachexia \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 WEIGHT DECREASED \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthritis \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 AGITATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Renal and urinary disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Urinary Retention \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 MICTURITION URGENCY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Bronchospasm \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DYSPNOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Eye disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Glaucoma \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 EYE SWELLING \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Viral Infection \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypotension \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4156 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5488 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6821 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8154 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10428 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DEHYDRATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae19b/tsfae19b.rtf b/tests/testthat/_snaps/tsfae18a/tsfae18a.rtf old mode 100755 new mode 100644 similarity index 54% rename from tests/testthat/_snaps/tsfae19b/tsfae19b.rtf rename to tests/testthat/_snaps/tsfae18a/tsfae18a.rtf index 7e04dbfe..f27e9e48 --- a/tests/testthat/_snaps/tsfae19b/tsfae19b.rtf +++ b/tests/testthat/_snaps/tsfae18a/tsfae18a.rtf @@ -3,12 +3,14 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2786 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3343 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3900 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5794 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9248 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE19b:\tab Dummy Title\b0 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2847 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3395 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3942 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4490 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6351 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE18a:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -19,12 +21,14 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2786 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3343 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3900 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5794 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9248 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2847 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3395 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3942 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4490 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6351 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9526 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Algorithmic OCMQ \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell @@ -35,31 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2786 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3343 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3900 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5794 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9248 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr OCMQ (Broad) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3395 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3942 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4490 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2786 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3343 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3900 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5794 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9248 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=29 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=34 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=23 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2847 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3395 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3942 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4490 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6351 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Criterion, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -67,60 +75,86 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2786 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3343 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3900 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5794 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9248 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Erectile Dysfunction \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3395 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3942 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4490 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 algorithmic criterion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3395 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3942 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4490 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Any muscle injury OCMQ narrow term \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.3%) \cell -\pard\intbl\qc\fs18 -4.3 (-12.7, 4.0) \cell -\pard\intbl\qc\fs18 -4.3 (-12.7, 4.0) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3343 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3900 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5794 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9248 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DISTURBANCE IN SEXUAL AROUSAL \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3395 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3942 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4490 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Urine myoglobin >ULN \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.3%) \cell -\pard\intbl\qc\fs18 -4.3 (-12.7, 4.0) \cell -\pard\intbl\qc\fs18 -4.3 (-12.7, 4.0) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3343 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3900 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5794 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9248 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3395 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3942 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4490 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CPK >5x ULN\super a\nosupersub \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2786 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3343 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3900 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5794 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9248 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gynecomastia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2847 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3395 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3942 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4490 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6351 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9526 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myalgia + weakness + chromaturia\super b\nosupersub \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -131,33 +165,37 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2786 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3343 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3900 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5794 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9248 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2847 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3395 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3942 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4490 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6351 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9526 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2786 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3343 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3900 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5794 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9248 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3395 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3942 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4490 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsfae18b/tsfae18b.rtf b/tests/testthat/_snaps/tsfae18b/tsfae18b.rtf new file mode 100644 index 00000000..b726bbe9 --- /dev/null +++ b/tests/testthat/_snaps/tsfae18b/tsfae18b.rtf @@ -0,0 +1,472 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2815 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4394 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5973 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7690 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9269 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11054 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE18b:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2815 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4394 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5973 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7690 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9269 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11054 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Population \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Algorithmic OCMQ Criterion, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 All subjects \cell +\pard\intbl\qc\fs18 67 (100.0%) \cell +\pard\intbl\qc\fs18 51 (100.0%) \cell +\pard\intbl\qc\fs18 118 (100.0%) \cell +\pard\intbl\qc\fs18 64 (100.0%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with \u8805?1 algorithmic criterion \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Any hypoglycemia OCMQ narrow term \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Plasma glucose <54 mg/dL \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Hypoglycemia term\super a\nosupersub + plasma glucose <70 mg/dL\super b\nosupersub \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 hypoglycemia terms\super a\nosupersub + \u8805?2 episodes of plasma glucose <70 mg/dL \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 No history of diabetes \cell +\pard\intbl\qc\fs18 55 (82.1%) \cell +\pard\intbl\qc\fs18 44 (86.3%) \cell +\pard\intbl\qc\fs18 99 (83.9%) \cell +\pard\intbl\qc\fs18 49 (76.6%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with \u8805?1 algorithmic criterion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Any hypoglycemia OCMQ narrow term \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Plasma glucose <54 mg/dL \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Hypoglycemia term\super a\nosupersub + plasma glucose <70 mg/dL\super b\nosupersub \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 hypoglycemia terms\super a\nosupersub + \u8805?2 episodes of plasma glucose <70 mg/dL \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 History of diabetes \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 15 (23.4%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with \u8805?1 algorithmic criterion \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Any hypoglycemia OCMQ narrow term \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Plasma glucose <54 mg/dL \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3.0 (-1.1, 7.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Hypoglycemia term\super a\nosupersub + plasma glucose <70 mg/dL\super b\nosupersub \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2815 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4394 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5973 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9269 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11054 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 hypoglycemia terms\super a\nosupersub + \u8805?2 episodes of plasma glucose <70 mg/dL \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2815 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4394 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5973 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7690 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9269 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11054 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4394 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5973 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9269 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11054 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae18c/tsfae18c.rtf b/tests/testthat/_snaps/tsfae18c/tsfae18c.rtf new file mode 100644 index 00000000..152866d1 --- /dev/null +++ b/tests/testthat/_snaps/tsfae18c/tsfae18c.rtf @@ -0,0 +1,634 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2857 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4254 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5652 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7171 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8569 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10696 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE18c:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2857 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4254 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5652 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7171 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8569 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10696 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Population \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Algorithmic OCMQ Criterion, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 All subjects \cell +\pard\intbl\qc\fs18 67 (100.0%) \cell +\pard\intbl\qc\fs18 51 (100.0%) \cell +\pard\intbl\qc\fs18 118 (100.0%) \cell +\pard\intbl\qc\fs18 64 (100.0%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with \u8805?1 algorithmic criterion \cell +\pard\intbl\qc\fs18 28 (41.8%) \cell +\pard\intbl\qc\fs18 33 (64.7%) \cell +\pard\intbl\qc\fs18 61 (51.7%) \cell +\pard\intbl\qc\fs18 39 (60.9%) \cell +\pard\intbl\qc\fs18 -19.1 (-35.9, -2.3) \cell +\pard\intbl\qc\fs18 3.8 (-14.0, 21.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Any hyperglycemia OCMQ narrow term \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Fasting plasma glucose \u8805?126 mg/dL \cell +\pard\intbl\qc\fs18 17 (25.4%) \cell +\pard\intbl\qc\fs18 19 (37.3%) \cell +\pard\intbl\qc\fs18 36 (30.5%) \cell +\pard\intbl\qc\fs18 31 (48.4%) \cell +\pard\intbl\qc\fs18 -23.1 (-39.1, -7.0) \cell +\pard\intbl\qc\fs18 -11.2 (-29.2, 6.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 plasma glucoses >180 mg/dL \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 -4.9 (-13.6, 3.8) \cell +\pard\intbl\qc\fs18 4.4 (-7.5, 16.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Any new diabetes concomitant medication \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Postbaseline HbA1c \u8805?6.5% \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 HbA1c increase \u8805?0.3% with postbaseline HbA1c \u8805?5.7% \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Change from baseline fasting plasma glucose \u8805?20 mg/dL with postbaseline fasting plasma glucose >100 mg/dL \cell +\pard\intbl\qc\fs18 24 (35.8%) \cell +\pard\intbl\qc\fs18 33 (64.7%) \cell +\pard\intbl\qc\fs18 57 (48.3%) \cell +\pard\intbl\qc\fs18 33 (51.6%) \cell +\pard\intbl\qc\fs18 -15.7 (-32.5, 1.0) \cell +\pard\intbl\qc\fs18 13.1 (-4.8, 31.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 No history of diabetes \cell +\pard\intbl\qc\fs18 55 (82.1%) \cell +\pard\intbl\qc\fs18 44 (86.3%) \cell +\pard\intbl\qc\fs18 99 (83.9%) \cell +\pard\intbl\qc\fs18 49 (76.6%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with \u8805?1 algorithmic criterion \cell +\pard\intbl\qc\fs18 22 (32.8%) \cell +\pard\intbl\qc\fs18 28 (54.9%) \cell +\pard\intbl\qc\fs18 50 (42.4%) \cell +\pard\intbl\qc\fs18 29 (45.3%) \cell +\pard\intbl\qc\fs18 -12.5 (-29.1, 4.1) \cell +\pard\intbl\qc\fs18 9.6 (-8.7, 27.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Any hyperglycemia OCMQ narrow term \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Fasting plasma glucose \u8805?126 mg/dL \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 16 (31.4%) \cell +\pard\intbl\qc\fs18 27 (22.9%) \cell +\pard\intbl\qc\fs18 23 (35.9%) \cell +\pard\intbl\qc\fs18 -19.5 (-34.2, -4.8) \cell +\pard\intbl\qc\fs18 -4.6 (-21.9, 12.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 plasma glucoses >180 mg/dL \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 -3.3 (-11.6, 4.9) \cell +\pard\intbl\qc\fs18 4.0 (-7.1, 15.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Any new diabetes concomitant medication \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Postbaseline HbA1c \u8805?6.5% \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 HbA1c increase \u8805?0.3% with postbaseline HbA1c \u8805?5.7% \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Change from baseline fasting plasma glucose \u8805?20 mg/dL with postbaseline fasting plasma glucose >100 mg/dL \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 28 (54.9%) \cell +\pard\intbl\qc\fs18 47 (39.8%) \cell +\pard\intbl\qc\fs18 24 (37.5%) \cell +\pard\intbl\qc\fs18 -9.1 (-25.2, 6.9) \cell +\pard\intbl\qc\fs18 17.4 (-0.7, 35.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 History of diabetes \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 15 (23.4%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects with \u8805?1 algorithmic criterion \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\pard\intbl\qc\fs18 -6.7 (-17.9, 4.5) \cell +\pard\intbl\qc\fs18 -5.8 (-17.9, 6.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Any hyperglycemia OCMQ narrow term \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Fasting plasma glucose \u8805?126 mg/dL \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 -3.5 (-14.1, 7.1) \cell +\pard\intbl\qc\fs18 -6.6 (-17.0, 3.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 plasma glucoses >180 mg/dL \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Any new diabetes concomitant medication \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Postbaseline HbA1c \u8805?6.5% \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 HbA1c increase \u8805?0.3% with postbaseline HbA1c \u8805?5.7% \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2857 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4254 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5652 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7171 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8569 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10696 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Change from baseline fasting plasma glucose \u8805?20 mg/dL with postbaseline fasting plasma glucose >100 mg/dL \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 -6.6 (-17.2, 4.0) \cell +\pard\intbl\qc\fs18 -4.3 (-16.1, 7.5) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2857 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4254 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5652 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7171 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8569 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10696 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7171 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8569 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10696 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae18d/tsfae18d.rtf b/tests/testthat/_snaps/tsfae18d/tsfae18d.rtf new file mode 100644 index 00000000..c89264ad --- /dev/null +++ b/tests/testthat/_snaps/tsfae18d/tsfae18d.rtf @@ -0,0 +1,202 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4320 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4753 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6221 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7690 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10196 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE18d:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2852 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4320 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4753 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6221 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7690 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10196 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Algorithmic OCMQ \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4320 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4320 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4753 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6221 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10196 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Criterion, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4320 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 algorithmic criterion\super a\nosupersub \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4320 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Any hypersensitivity OCMQ narrow term \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 -1.6 (-6.8, 3.5) \cell +\pard\intbl\qc\fs18 -3.1 (-7.4, 1.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4320 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Respiratory + skin reaction \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4320 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Respiratory + systemic reaction \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4320 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4753 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6221 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7690 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10196 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin + systemic reaction \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4320 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4753 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6221 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7690 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10196 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4320 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae19c/tsfae19c.rtf b/tests/testthat/_snaps/tsfae19c/tsfae19c.rtf deleted file mode 100755 index 71b1293e..00000000 --- a/tests/testthat/_snaps/tsfae19c/tsfae19c.rtf +++ /dev/null @@ -1,276 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2767 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4905 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5534 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6162 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9683 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE19c:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2767 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4905 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5534 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6162 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9683 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr OCMQ (Narrow) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=24 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=39 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=36 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Abnormal Uterine Bleeding \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4.2 (-3.8, 12.2) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABNORMAL UTERINE BLEEDING \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4.2 (-3.8, 12.2) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Amenorrhea \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Bacterial Vaginosis \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Decreased Menstrual Bleeding \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Excessive Menstrual Bleeding \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4.2 (-3.8, 12.2) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2767 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4905 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5534 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6162 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9683 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABNORMAL UTERINE BLEEDING \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4.2 (-3.8, 12.2) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2767 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4905 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5534 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6162 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9683 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2767 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4905 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5534 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6162 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9683 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae19d/tsfae19d.rtf b/tests/testthat/_snaps/tsfae19d/tsfae19d.rtf deleted file mode 100755 index 22c7f8c6..00000000 --- a/tests/testthat/_snaps/tsfae19d/tsfae19d.rtf +++ /dev/null @@ -1,260 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2845 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3354 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5081 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6808 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9755 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE19d:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2845 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3354 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5081 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6808 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9755 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr OCMQ (Broad) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3354 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6808 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9755 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=24 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=39 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=36 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Abnormal Uterine Bleeding \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 1 (2.8%) \cell -\pard\intbl\qc\fs18 -2.8 (-8.1, 2.6) \cell -\pard\intbl\qc\fs18 -0.2 (-7.5, 7.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLEEDING ANOVULATORY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 1 (2.8%) \cell -\pard\intbl\qc\fs18 -2.8 (-8.1, 2.6) \cell -\pard\intbl\qc\fs18 -0.2 (-7.5, 7.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Amenorrhea \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Bacterial Vaginosis \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Decreased Menstrual Bleeding \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3354 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6808 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9755 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Excessive Menstrual Bleeding \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2845 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3354 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5081 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6808 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9755 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3354 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6808 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9755 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae20a/tsfae20a.rtf b/tests/testthat/_snaps/tsfae20a/tsfae20a.rtf old mode 100755 new mode 100644 index 711192c0..f419b746 --- a/tests/testthat/_snaps/tsfae20a/tsfae20a.rtf +++ b/tests/testthat/_snaps/tsfae20a/tsfae20a.rtf @@ -4,220 +4,644 @@ { \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5381 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10320 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11055 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE20a:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5381 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6116 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7762 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10320 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9408 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11055 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx4469 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx6116 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7762 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx9408 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx11055 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=64 \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Characteristic \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr Related AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr Related AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr Related AEs \cell \row } { \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 106 (84.1%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 48 (71.6%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 45 (88.2%) \cell +\pard\intbl\qc\fs18 38 (59.4%) \cell +\pard\intbl\qc\fs18 34 (53.1%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sex, n/Ns (%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 21 (31.3%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Male \cell -\pard\intbl\qc\fs18 28/29 (96.6%) \cell -\pard\intbl\qc\fs18 27/34 (79.4%) \cell -\pard\intbl\qc\fs18 55/63 (87.3%) \cell -\pard\intbl\qc\fs18 12/23 (52.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Female \cell -\pard\intbl\qc\fs18 23/24 (95.8%) \cell -\pard\intbl\qc\fs18 28/39 (71.8%) \cell -\pard\intbl\qc\fs18 51/63 (81.0%) \cell -\pard\intbl\qc\fs18 21/36 (58.3%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age group (years), n/Ns (%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?18 to <65 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 13/13 (100.0%) \cell -\pard\intbl\qc\fs18 2/7 (28.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?65 to <75 \cell -\pard\intbl\qc\fs18 14/16 (87.5%) \cell -\pard\intbl\qc\fs18 15/17 (88.2%) \cell -\pard\intbl\qc\fs18 29/33 (87.9%) \cell -\pard\intbl\qc\fs18 10/19 (52.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?75 \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 35/51 (68.6%) \cell -\pard\intbl\qc\fs18 64/80 (80.0%) \cell -\pard\intbl\qc\fs18 21/33 (63.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race, n/Ns (%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -228,210 +652,432 @@ { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 American Indian or Alaska Native \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 7/10 (70.0%) \cell -\pard\intbl\qc\fs18 12/15 (80.0%) \cell -\pard\intbl\qc\fs18 2/3 (66.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Asian \cell -\pard\intbl\qc\fs18 10/10 (100.0%) \cell -\pard\intbl\qc\fs18 7/9 (77.8%) \cell -\pard\intbl\qc\fs18 17/19 (89.5%) \cell -\pard\intbl\qc\fs18 4/5 (80.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Black or African American \cell -\pard\intbl\qc\fs18 3/3 (100.0%) \cell -\pard\intbl\qc\fs18 6/11 (54.5%) \cell -\pard\intbl\qc\fs18 9/14 (64.3%) \cell -\pard\intbl\qc\fs18 3/7 (42.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 12/12 (100.0%) \cell -\pard\intbl\qc\fs18 3/5 (60.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial fibrillation \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 White \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 7/8 (87.5%) \cell -\pard\intbl\qc\fs18 15/16 (93.8%) \cell -\pard\intbl\qc\fs18 5/7 (71.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Multiple \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 8/10 (80.0%) \cell -\pard\intbl\qc\fs18 16/18 (88.9%) \cell -\pard\intbl\qc\fs18 1/5 (20.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not reported or unknown \cell -\pard\intbl\qc\fs18 9/11 (81.8%) \cell -\pard\intbl\qc\fs18 9/12 (75.0%) \cell -\pard\intbl\qc\fs18 18/23 (78.3%) \cell -\pard\intbl\qc\fs18 11/17 (64.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell -\pard\intbl\qc\fs18 1/1 (100.0%) \cell -\pard\intbl\qc\fs18 6/8 (75.0%) \cell -\pard\intbl\qc\fs18 7/9 (77.8%) \cell -\pard\intbl\qc\fs18 4/10 (40.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ethnicity, n/Ns (%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hispanic or Latino \cell -\pard\intbl\qc\fs18 14/15 (93.3%) \cell -\pard\intbl\qc\fs18 12/15 (80.0%) \cell -\pard\intbl\qc\fs18 26/30 (86.7%) \cell -\pard\intbl\qc\fs18 7/12 (58.3%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not Hispanic or Latino \cell -\pard\intbl\qc\fs18 14/15 (93.3%) \cell -\pard\intbl\qc\fs18 13/18 (72.2%) \cell -\pard\intbl\qc\fs18 27/33 (81.8%) \cell -\pard\intbl\qc\fs18 11/16 (68.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5381 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4469 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10320 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not reported or unknown \cell -\pard\intbl\qc\fs18 23/23 (100.0%) \cell -\pard\intbl\qc\fs18 30/40 (75.0%) \cell -\pard\intbl\qc\fs18 53/63 (84.1%) \cell -\pard\intbl\qc\fs18 15/31 (48.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11055 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5381 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6116 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10320 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11055 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5381 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4469 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6116 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10320 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9408 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11055 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsfae20b/tsfae20b.rtf b/tests/testthat/_snaps/tsfae20b/tsfae20b.rtf old mode 100755 new mode 100644 index 3111e9b4..38382519 --- a/tests/testthat/_snaps/tsfae20b/tsfae20b.rtf +++ b/tests/testthat/_snaps/tsfae20b/tsfae20b.rtf @@ -3,221 +3,591 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2833 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5300 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7767 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10234 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4058 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6527 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8997 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11466 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE20b:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2833 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5300 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7767 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10234 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4058 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6527 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8997 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10232 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11466 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Characteristic \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx4058 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5292 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx6527 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7762 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx8997 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx10232 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx11466 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=64 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 SAE \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 43 (58.9%) \cell -\pard\intbl\qc\fs18 86 (68.3%) \cell -\pard\intbl\qc\fs18 27 (45.8%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805? Grade 3 AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805? Grade 3 AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805? Grade 3 AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell +\pard\intbl\qc\fs18 \keepn\trhdr \u8805? Grade 3 AEs \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 44 (65.7%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 37 (72.5%) \cell +\pard\intbl\qc\fs18 96 (81.4%) \cell +\pard\intbl\qc\fs18 81 (68.6%) \cell +\pard\intbl\qc\fs18 38 (59.4%) \cell +\pard\intbl\qc\fs18 32 (50.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sex, n/Ns (%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 16 (31.4%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 34 (28.8%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 28 (23.7%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Male \cell -\pard\intbl\qc\fs18 25/29 (86.2%) \cell -\pard\intbl\qc\fs18 21/34 (61.8%) \cell -\pard\intbl\qc\fs18 46/63 (73.0%) \cell -\pard\intbl\qc\fs18 11/23 (47.8%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Female \cell -\pard\intbl\qc\fs18 18/24 (75.0%) \cell -\pard\intbl\qc\fs18 22/39 (56.4%) \cell -\pard\intbl\qc\fs18 40/63 (63.5%) \cell -\pard\intbl\qc\fs18 16/36 (44.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age group (years), n/Ns (%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 17 (25.4%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 15 (29.4%) \cell +\pard\intbl\qc\fs18 48 (40.7%) \cell +\pard\intbl\qc\fs18 32 (27.1%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 19 (16.1%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?18 to <65 \cell -\pard\intbl\qc\fs18 7/8 (87.5%) \cell -\pard\intbl\qc\fs18 4/5 (80.0%) \cell -\pard\intbl\qc\fs18 11/13 (84.6%) \cell -\pard\intbl\qc\fs18 2/7 (28.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?65 to <75 \cell -\pard\intbl\qc\fs18 11/16 (68.8%) \cell -\pard\intbl\qc\fs18 11/17 (64.7%) \cell -\pard\intbl\qc\fs18 22/33 (66.7%) \cell -\pard\intbl\qc\fs18 9/19 (47.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?75 \cell -\pard\intbl\qc\fs18 25/29 (86.2%) \cell -\pard\intbl\qc\fs18 28/51 (54.9%) \cell -\pard\intbl\qc\fs18 53/80 (66.2%) \cell -\pard\intbl\qc\fs18 16/33 (48.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 27 (22.9%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race, n/Ns (%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -227,137 +597,283 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 American Indian or Alaska Native \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 7/10 (70.0%) \cell -\pard\intbl\qc\fs18 12/15 (80.0%) \cell -\pard\intbl\qc\fs18 1/3 (33.3%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Asian \cell -\pard\intbl\qc\fs18 7/10 (70.0%) \cell -\pard\intbl\qc\fs18 6/9 (66.7%) \cell -\pard\intbl\qc\fs18 13/19 (68.4%) \cell -\pard\intbl\qc\fs18 4/5 (80.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Black or African American \cell -\pard\intbl\qc\fs18 2/3 (66.7%) \cell -\pard\intbl\qc\fs18 5/11 (45.5%) \cell -\pard\intbl\qc\fs18 7/14 (50.0%) \cell -\pard\intbl\qc\fs18 3/7 (42.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs18 6/7 (85.7%) \cell -\pard\intbl\qc\fs18 2/5 (40.0%) \cell -\pard\intbl\qc\fs18 8/12 (66.7%) \cell -\pard\intbl\qc\fs18 2/5 (40.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 White \cell -\pard\intbl\qc\fs18 7/8 (87.5%) \cell -\pard\intbl\qc\fs18 5/8 (62.5%) \cell -\pard\intbl\qc\fs18 12/16 (75.0%) \cell -\pard\intbl\qc\fs18 3/7 (42.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Multiple \cell -\pard\intbl\qc\fs18 7/8 (87.5%) \cell -\pard\intbl\qc\fs18 6/10 (60.0%) \cell -\pard\intbl\qc\fs18 13/18 (72.2%) \cell -\pard\intbl\qc\fs18 1/5 (20.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 16 (13.6%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not reported or unknown \cell -\pard\intbl\qc\fs18 8/11 (72.7%) \cell -\pard\intbl\qc\fs18 6/12 (50.0%) \cell -\pard\intbl\qc\fs18 14/23 (60.9%) \cell -\pard\intbl\qc\fs18 10/17 (58.8%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell -\pard\intbl\qc\fs18 1/1 (100.0%) \cell -\pard\intbl\qc\fs18 6/8 (75.0%) \cell -\pard\intbl\qc\fs18 7/9 (77.8%) \cell -\pard\intbl\qc\fs18 3/10 (30.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ethnicity, n/Ns (%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -367,71 +883,221 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hispanic or Latino \cell -\pard\intbl\qc\fs18 13/15 (86.7%) \cell -\pard\intbl\qc\fs18 10/15 (66.7%) \cell -\pard\intbl\qc\fs18 23/30 (76.7%) \cell -\pard\intbl\qc\fs18 6/12 (50.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not Hispanic or Latino \cell -\pard\intbl\qc\fs18 11/15 (73.3%) \cell -\pard\intbl\qc\fs18 11/18 (61.1%) \cell -\pard\intbl\qc\fs18 22/33 (66.7%) \cell -\pard\intbl\qc\fs18 8/16 (50.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2833 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5300 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7767 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10234 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Not reported or unknown \cell -\pard\intbl\qc\fs18 19/23 (82.6%) \cell -\pard\intbl\qc\fs18 22/40 (55.0%) \cell -\pard\intbl\qc\fs18 41/63 (65.1%) \cell -\pard\intbl\qc\fs18 13/31 (41.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4058 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8997 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2833 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5300 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7767 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10234 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4058 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6527 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8997 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11466 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5300 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4058 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8997 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsfae20c/tsfae20cpart1of2.rtf b/tests/testthat/_snaps/tsfae20c/tsfae20cpart1of2.rtf new file mode 100644 index 00000000..14aa25b9 --- /dev/null +++ b/tests/testthat/_snaps/tsfae20c/tsfae20cpart1of2.rtf @@ -0,0 +1,1774 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4675 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5910 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6527 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7145 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9614 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10849 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11466 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12084 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE20cpart1of2:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4675 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5910 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6527 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7145 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9614 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10849 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11466 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12084 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx4675 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5910 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx6527 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7145 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7762 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx9614 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx10849 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx11466 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx12084 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Xanomeline High Dose \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\pard\intbl\qc\fs18 \keepn\trhdr Within 3 months \cell +\pard\intbl\qc\fs18 \keepn\trhdr 4 to 6 months \cell +\pard\intbl\qc\fs18 \keepn\trhdr 7 to 9 months \cell +\pard\intbl\qc\fs18 \keepn\trhdr 10 to 12 months \cell +\pard\intbl\qc\fs18 \keepn\trhdr Beyond 13 months \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\pard\intbl\qc\fs18 \keepn\trhdr Within 3 months \cell +\pard\intbl\qc\fs18 \keepn\trhdr 4 to 6 months \cell +\pard\intbl\qc\fs18 \keepn\trhdr 7 to 9 months \cell +\pard\intbl\qc\fs18 \keepn\trhdr 10 to 12 months \cell +\pard\intbl\qc\fs18 \keepn\trhdr Beyond 13 months \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 13 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell +\pard\intbl\qc\fs18 40 (59.7%) \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 34 (66.7%) \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 24 (47.1%) \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4675 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5910 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6527 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7145 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9614 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10849 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11466 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12084 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4675 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5910 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6527 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7145 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9614 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10849 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11466 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12084 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4675 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5910 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6527 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7145 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9614 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10849 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11466 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12084 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae24fpart1/tsfae24fpart1of3.rtf b/tests/testthat/_snaps/tsfae20d/tsfae20dpart1of3.rtf old mode 100755 new mode 100644 similarity index 51% rename from tests/testthat/_snaps/tsfae24fpart1/tsfae24fpart1of3.rtf rename to tests/testthat/_snaps/tsfae20d/tsfae20dpart1of3.rtf index 7c48c20a..7653edb5 --- a/tests/testthat/_snaps/tsfae24fpart1/tsfae24fpart1of3.rtf +++ b/tests/testthat/_snaps/tsfae20d/tsfae20dpart1of3.rtf @@ -5,11 +5,11 @@ \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2832 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4531 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5906 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7605 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9142 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10841 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE24fpart1of3:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6068 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7767 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9465 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11002 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE20dpart1of3:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -23,10 +23,10 @@ \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2832 \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4531 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5906 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7605 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9142 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10841 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6068 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7767 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9465 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11002 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -41,17 +41,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4531 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5906 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7605 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9142 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10841 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6068 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7767 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9465 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11002 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell \row } @@ -59,10 +59,10 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2832 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4531 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5906 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7605 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9142 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10841 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6068 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7767 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9465 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11002 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell \pard\intbl\qc\fs18 \keepn\trhdr Within 3 months \cell @@ -77,16 +77,16 @@ \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 49 \cell -\pard\intbl\qc\fs18 38 \cell -\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 26 \cell \pard\intbl\qc\fs18 14 \cell \row } @@ -95,10 +95,10 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -113,17 +113,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 11 (22.4%) \cell -\pard\intbl\qc\fs18 7 (18.4%) \cell -\pard\intbl\qc\fs18 15 (50.0%) \cell -\pard\intbl\qc\fs18 14 (100.0%) \cell +\pard\intbl\qc\fs18 50 (74.6%) \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 12 (21.8%) \cell +\pard\intbl\qc\fs18 12 (30.0%) \cell +\pard\intbl\qc\fs18 8 (30.8%) \cell +\pard\intbl\qc\fs18 10 (71.4%) \cell \row } @@ -131,10 +131,10 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -149,17 +149,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (8.2%) \cell -\pard\intbl\qc\fs18 6 (15.8%) \cell -\pard\intbl\qc\fs18 9 (30.0%) \cell -\pard\intbl\qc\fs18 8 (57.1%) \cell +\pard\intbl\qc\fs18 23 (34.3%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (12.7%) \cell +\pard\intbl\qc\fs18 4 (10.0%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\pard\intbl\qc\fs18 5 (35.7%) \cell \row } @@ -167,17 +167,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (4.1%) \cell -\pard\intbl\qc\fs18 6 (15.8%) \cell -\pard\intbl\qc\fs18 5 (16.7%) \cell -\pard\intbl\qc\fs18 6 (42.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pruritus \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.3%) \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 2 (14.3%) \cell \row } @@ -185,17 +185,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (4.1%) \cell -\pard\intbl\qc\fs18 4 (10.5%) \cell -\pard\intbl\qc\fs18 3 (10.0%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erythema \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -203,17 +203,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperhidrosis \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (10.0%) \cell -\pard\intbl\qc\fs18 3 (21.4%) \cell \row } @@ -221,17 +221,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rash \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.6%) \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 2 (6.7%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell +\pard\intbl\qc\fs18 3 (21.4%) \cell \row } @@ -239,16 +239,16 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin irritation \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell \pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -257,16 +257,16 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blister \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.5%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -275,10 +275,10 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -293,35 +293,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 7 (14.3%) \cell -\pard\intbl\qc\fs18 2 (5.3%) \cell -\pard\intbl\qc\fs18 7 (23.3%) \cell -\pard\intbl\qc\fs18 6 (42.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 5 (10.2%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 3 (10.0%) \cell -\pard\intbl\qc\fs18 3 (21.4%) \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.1%) \cell +\pard\intbl\qc\fs18 6 (15.0%) \cell +\pard\intbl\qc\fs18 5 (19.2%) \cell +\pard\intbl\qc\fs18 7 (50.0%) \cell \row } @@ -329,17 +311,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (8.2%) \cell -\pard\intbl\qc\fs18 2 (5.3%) \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell -\pard\intbl\qc\fs18 3 (21.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site pruritus \cell +\pard\intbl\qc\fs18 15 (22.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\pard\intbl\qc\fs18 5 (12.5%) \cell +\pard\intbl\qc\fs18 4 (15.4%) \cell +\pard\intbl\qc\fs18 4 (28.6%) \cell \row } @@ -347,17 +329,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (4.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site erythema \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.5%) \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell -\pard\intbl\qc\fs18 5 (35.7%) \cell \row } @@ -365,17 +347,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site irritation \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.7%) \cell -\pard\intbl\qc\fs18 3 (21.4%) \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -383,17 +365,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.7%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -401,17 +383,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site dermatitis \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 4 (28.6%) \cell \row } @@ -419,17 +401,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Application site vesicles \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -437,10 +419,10 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -455,16 +437,34 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (4.1%) \cell -\pard\intbl\qc\fs18 2 (5.3%) \cell -\pard\intbl\qc\fs18 7 (23.3%) \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.3%) \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 3 (21.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.6%) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell \pard\intbl\qc\fs18 2 (14.3%) \cell \row } @@ -473,16 +473,16 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (4.1%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 4 (13.3%) \cell \pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -491,17 +491,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -509,16 +509,16 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Somnolence \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -527,10 +527,10 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -545,16 +545,34 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (21.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nausea \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (4.1%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 6 (20.0%) \cell \pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -563,16 +581,16 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Vomiting \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 (16.7%) \cell \pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -581,17 +599,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (4.1%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -599,17 +617,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -617,10 +635,10 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -635,17 +653,35 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus bradycardia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (8.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (13.3%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -653,17 +689,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (6.1%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell \row } @@ -671,16 +707,34 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (6.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.7%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -689,16 +743,16 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasopharyngitis \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.7%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -707,10 +761,28 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -725,17 +797,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (10.0%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (21.4%) \cell \row } @@ -743,17 +815,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.7%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (21.4%) \cell \row } @@ -761,17 +833,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nasal congestion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -779,10 +851,10 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -797,17 +869,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.7%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -815,16 +887,16 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell \pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -833,17 +905,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -851,10 +923,10 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -869,17 +941,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -887,17 +959,17 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Contusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -905,10 +977,10 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -923,16 +995,16 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell \pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -941,16 +1013,16 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2832 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4531 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7605 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9142 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10841 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6068 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7767 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9465 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11002 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anxiety \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.3%) \cell \pard\intbl\qc\fs18 1 (7.1%) \cell \row } @@ -959,10 +1031,10 @@ \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2832 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4531 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5906 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7605 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9142 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10841 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6068 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7767 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9465 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11002 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -977,10 +1049,10 @@ \trowd \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4531 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7605 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9142 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10841 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6068 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7767 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9465 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11002 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfae21apart1/tsfae21apart1of4.rtf b/tests/testthat/_snaps/tsfae21apart1/tsfae21apart1of4.rtf deleted file mode 100755 index 2710da1e..00000000 --- a/tests/testthat/_snaps/tsfae21apart1/tsfae21apart1of4.rtf +++ /dev/null @@ -1,772 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE21apart1of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2828 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mild \cell -\pard\intbl\qc\fs18 \keepn\trhdr Moderate \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 19 (35.8%) \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 9 (17.0%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae21apart2/tsfae21apart2of4.rtf b/tests/testthat/_snaps/tsfae21apart2/tsfae21apart2of4.rtf deleted file mode 100755 index 87315e97..00000000 --- a/tests/testthat/_snaps/tsfae21apart2/tsfae21apart2of4.rtf +++ /dev/null @@ -1,900 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4516 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6179 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7843 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE21apart2of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2852 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4516 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6179 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7843 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4516 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6179 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7843 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6179 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7843 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4516 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6179 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7843 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mild \cell -\pard\intbl\qc\fs18 \keepn\trhdr Moderate \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severe \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4516 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6179 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7843 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6179 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7843 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4516 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6179 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7843 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae21apart3/tsfae21apart3of4.rtf b/tests/testthat/_snaps/tsfae21apart3/tsfae21apart3of4.rtf deleted file mode 100755 index 63147a95..00000000 --- a/tests/testthat/_snaps/tsfae21apart3/tsfae21apart3of4.rtf +++ /dev/null @@ -1,900 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4634 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6255 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7877 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE21apart3of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2858 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4634 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6255 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7877 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4634 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6255 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7877 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6255 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7877 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4634 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6255 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7877 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mild \cell -\pard\intbl\qc\fs18 \keepn\trhdr Moderate \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severe \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 106 (84.1%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 56 (44.4%) \cell -\pard\intbl\qc\fs18 28 (22.2%) \cell -\pard\intbl\qc\fs18 24 (19.0%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 19 (15.1%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 25 (19.8%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4634 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6255 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7877 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4634 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6255 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7877 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4634 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6255 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7877 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae21apart4/tsfae21apart4of4.rtf b/tests/testthat/_snaps/tsfae21apart4/tsfae21apart4of4.rtf deleted file mode 100755 index a24543b7..00000000 --- a/tests/testthat/_snaps/tsfae21apart4/tsfae21apart4of4.rtf +++ /dev/null @@ -1,900 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2847 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4554 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6262 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7807 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE21apart4of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2847 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4554 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6262 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7807 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4554 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6262 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7807 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6262 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7807 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severity \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4554 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6262 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7807 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mild \cell -\pard\intbl\qc\fs18 \keepn\trhdr Moderate \cell -\pard\intbl\qc\fs18 \keepn\trhdr Severe \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 9 (15.3%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 11 (18.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6262 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7807 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2847 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4554 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6262 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7807 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6262 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7807 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae21bpart1/tsfae21bpart1of4.rtf b/tests/testthat/_snaps/tsfae21bpart1/tsfae21bpart1of4.rtf deleted file mode 100755 index 1bba37cf..00000000 --- a/tests/testthat/_snaps/tsfae21bpart1/tsfae21bpart1of4.rtf +++ /dev/null @@ -1,1156 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2813 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4603 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6053 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7672 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9121 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10911 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE21bpart1of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2813 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4603 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6053 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7672 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9121 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10911 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4603 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6053 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7672 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9121 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10911 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6053 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7672 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9121 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10911 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4603 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6053 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7672 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9121 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10911 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr 1 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 2 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 3 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 4 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 5 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6053 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9121 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10911 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2813 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4603 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6053 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7672 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9121 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10911 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6053 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9121 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10911 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae21bpart3/tsfae21bpart3of4.rtf b/tests/testthat/_snaps/tsfae21bpart3/tsfae21bpart3of4.rtf deleted file mode 100755 index 45481bb2..00000000 --- a/tests/testthat/_snaps/tsfae21bpart3/tsfae21bpart3of4.rtf +++ /dev/null @@ -1,1156 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2841 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4763 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6184 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7771 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10947 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE21bpart3of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2841 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4763 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6184 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7771 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10947 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4763 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6184 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7771 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9192 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10947 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6184 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7771 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10947 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4763 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6184 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7771 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9192 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10947 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr 1 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 2 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 3 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 4 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 5 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 106 (84.1%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 56 (44.4%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 19 (15.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 23 (18.3%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6184 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7771 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9192 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10947 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2841 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4763 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6184 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7771 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9192 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10947 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6184 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7771 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9192 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10947 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae21bpart4/tsfae21bpart4of4.rtf b/tests/testthat/_snaps/tsfae21bpart4/tsfae21bpart4of4.rtf deleted file mode 100755 index 2a8f709b..00000000 --- a/tests/testthat/_snaps/tsfae21bpart4/tsfae21bpart4of4.rtf +++ /dev/null @@ -1,1156 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2802 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4763 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6351 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7938 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11114 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE21bpart4of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2802 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4763 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6351 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7938 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11114 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4763 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6351 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7938 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11114 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6351 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7938 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11114 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\pard\intbl\qc\fs18 \keepn\trhdr Toxicity Grade \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4763 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6351 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7938 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11114 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr 1 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 2 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 3 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 4 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 5 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4763 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7938 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11114 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2802 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4763 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6351 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7938 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11114 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4763 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7938 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11114 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae21c/tsfae21c.rtf b/tests/testthat/_snaps/tsfae21c/tsfae21c.rtf deleted file mode 100755 index dd202e7c..00000000 --- a/tests/testthat/_snaps/tsfae21c/tsfae21c.rtf +++ /dev/null @@ -1,2160 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2134 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7466 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE21c:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2134 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7466 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 106 (84.1%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 56 (44.4%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 19 (15.1%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mild \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Moderate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2134 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7466 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae21d/tsfae21d.rtf b/tests/testthat/_snaps/tsfae21d/tsfae21d.rtf deleted file mode 100755 index 66236b88..00000000 --- a/tests/testthat/_snaps/tsfae21d/tsfae21d.rtf +++ /dev/null @@ -1,3168 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2134 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7466 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE21d:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2134 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7466 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 106 (84.1%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 56 (44.4%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missing \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7466 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2134 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7466 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7466 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae22apart1/tsfae22apart1of4.rtf b/tests/testthat/_snaps/tsfae22apart1/tsfae22apart1of4.rtf deleted file mode 100755 index 591ebb69..00000000 --- a/tests/testthat/_snaps/tsfae22apart1/tsfae22apart1of4.rtf +++ /dev/null @@ -1,1044 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2116 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3504 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4892 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6281 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7801 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE22apart1of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2116 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3504 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4892 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6281 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7801 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3504 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4892 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6281 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7801 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4892 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6281 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7801 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3504 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4892 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6281 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7801 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr White \cell -\pard\intbl\qc\fs18 \keepn\trhdr Black \cell -\pard\intbl\qc\fs18 \keepn\trhdr Asian \cell -\pard\intbl\qc\fs18 \keepn\trhdr Other \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 47 \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 10 \cell -\pard\intbl\qc\fs18 26 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 46 (97.9%) \cell -\pard\intbl\qc\fs18 8 (100.0%) \cell -\pard\intbl\qc\fs18 3 (100.0%) \cell -\pard\intbl\qc\fs18 10 (100.0%) \cell -\pard\intbl\qc\fs18 25 (96.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 28 (59.6%) \cell -\pard\intbl\qc\fs18 6 (75.0%) \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 8 (80.0%) \cell -\pard\intbl\qc\fs18 13 (50.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 18 (38.3%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 4 (40.0%) \cell -\pard\intbl\qc\fs18 10 (38.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (21.3%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 (23.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (10.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 3 (11.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 7 (14.9%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 2 (7.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (8.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (2.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 20 (42.6%) \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 2 (66.7%) \cell -\pard\intbl\qc\fs18 4 (40.0%) \cell -\pard\intbl\qc\fs18 9 (34.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 12 (25.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 8 (30.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 9 (19.1%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 5 (19.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 5 (10.6%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (15.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (8.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (7.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 3 (6.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (11.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 3 (6.4%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (2.1%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (27.7%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 8 (30.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (17.0%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 5 (19.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (10.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (10.0%) \cell -\pard\intbl\qc\fs18 4 (15.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (2.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (2.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (10.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 9 (19.1%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 5 (19.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (10.6%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (4.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (7.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 4 (8.5%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (7.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (21.3%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 6 (23.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (14.9%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 4 (15.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (6.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (2.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (10.6%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (10.0%) \cell -\pard\intbl\qc\fs18 3 (11.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (6.4%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (7.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (6.4%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (10.0%) \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (10.6%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (11.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (6.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (11.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (4.3%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (4.3%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (4.3%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (2.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (4.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2 (4.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (2.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2116 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3504 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4892 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6281 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7801 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (2.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2116 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3504 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4892 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6281 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7801 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2116 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3504 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4892 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6281 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7801 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae22apart2/tsfae22apart2of4.rtf b/tests/testthat/_snaps/tsfae22apart2/tsfae22apart2of4.rtf deleted file mode 100755 index 801eb32d..00000000 --- a/tests/testthat/_snaps/tsfae22apart2/tsfae22apart2of4.rtf +++ /dev/null @@ -1,1044 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2137 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3633 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE22apart2of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2137 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3633 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3633 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3633 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4987 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6340 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7693 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr White \cell -\pard\intbl\qc\fs18 \keepn\trhdr Black \cell -\pard\intbl\qc\fs18 \keepn\trhdr Asian \cell -\pard\intbl\qc\fs18 \keepn\trhdr Other \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 68 \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 9 \cell -\pard\intbl\qc\fs18 40 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 51 (75.0%) \cell -\pard\intbl\qc\fs18 7 (87.5%) \cell -\pard\intbl\qc\fs18 6 (54.5%) \cell -\pard\intbl\qc\fs18 7 (77.8%) \cell -\pard\intbl\qc\fs18 31 (77.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 24 (35.3%) \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 3 (27.3%) \cell -\pard\intbl\qc\fs18 4 (44.4%) \cell -\pard\intbl\qc\fs18 13 (32.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 14 (20.6%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 2 (22.2%) \cell -\pard\intbl\qc\fs18 8 (20.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 8 (11.8%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 (15.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 8 (11.8%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 2 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 3 (4.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (22.2%) \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (5.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 3 (7.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 2 (2.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 29 (42.6%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 3 (27.3%) \cell -\pard\intbl\qc\fs18 5 (55.6%) \cell -\pard\intbl\qc\fs18 19 (47.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 17 (25.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 3 (33.3%) \cell -\pard\intbl\qc\fs18 12 (30.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (14.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 2 (22.2%) \cell -\pard\intbl\qc\fs18 7 (17.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 7 (10.3%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 4 (10.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 7 (10.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (5.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 3 (7.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 3 (4.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 11 (16.2%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (22.2%) \cell -\pard\intbl\qc\fs18 8 (20.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 6 (8.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 5 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 3 (4.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 2 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 3 (4.4%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 2 (2.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 7 (10.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 5 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 2 (2.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 3 (4.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 2 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 2 (2.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 5 (7.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 3 (4.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (7.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 4 (5.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (10.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 4 (5.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (10.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 3 (4.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (4.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (2.9%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2137 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3633 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae22apart3/tsfae22apart3of4.rtf b/tests/testthat/_snaps/tsfae22apart3/tsfae22apart3of4.rtf deleted file mode 100755 index f0c8aa8f..00000000 --- a/tests/testthat/_snaps/tsfae22apart3/tsfae22apart3of4.rtf +++ /dev/null @@ -1,1044 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2126 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3566 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5006 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6309 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7749 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE22apart3of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2126 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3566 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5006 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6309 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7749 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3566 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5006 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6309 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7749 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5006 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6309 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7749 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3566 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5006 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6309 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7749 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr White \cell -\pard\intbl\qc\fs18 \keepn\trhdr Black \cell -\pard\intbl\qc\fs18 \keepn\trhdr Asian \cell -\pard\intbl\qc\fs18 \keepn\trhdr Other \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 115 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 14 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 66 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 97 (84.3%) \cell -\pard\intbl\qc\fs18 15 (93.8%) \cell -\pard\intbl\qc\fs18 9 (64.3%) \cell -\pard\intbl\qc\fs18 17 (89.5%) \cell -\pard\intbl\qc\fs18 56 (84.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 52 (45.2%) \cell -\pard\intbl\qc\fs18 10 (62.5%) \cell -\pard\intbl\qc\fs18 4 (28.6%) \cell -\pard\intbl\qc\fs18 12 (63.2%) \cell -\pard\intbl\qc\fs18 26 (39.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 32 (27.8%) \cell -\pard\intbl\qc\fs18 6 (37.5%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell -\pard\intbl\qc\fs18 6 (31.6%) \cell -\pard\intbl\qc\fs18 18 (27.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 18 (15.7%) \cell -\pard\intbl\qc\fs18 4 (25.0%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12 (18.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 13 (11.3%) \cell -\pard\intbl\qc\fs18 3 (18.8%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell -\pard\intbl\qc\fs18 3 (15.8%) \cell -\pard\intbl\qc\fs18 5 (7.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 10 (8.7%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 (26.3%) \cell -\pard\intbl\qc\fs18 3 (4.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 8 (7.0%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (15.8%) \cell -\pard\intbl\qc\fs18 4 (6.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 3 (2.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 49 (42.6%) \cell -\pard\intbl\qc\fs18 7 (43.8%) \cell -\pard\intbl\qc\fs18 5 (35.7%) \cell -\pard\intbl\qc\fs18 9 (47.4%) \cell -\pard\intbl\qc\fs18 28 (42.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 29 (25.2%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell -\pard\intbl\qc\fs18 6 (31.6%) \cell -\pard\intbl\qc\fs18 20 (30.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 19 (16.5%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell -\pard\intbl\qc\fs18 5 (26.3%) \cell -\pard\intbl\qc\fs18 12 (18.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 12 (10.4%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 8 (12.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 11 (9.6%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 3 (21.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7 (10.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 7 (6.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 6 (9.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 6 (5.2%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 2 (1.7%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 24 (20.9%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell -\pard\intbl\qc\fs18 5 (26.3%) \cell -\pard\intbl\qc\fs18 16 (24.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 14 (12.2%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (15.8%) \cell -\pard\intbl\qc\fs18 10 (15.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 8 (7.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 6 (9.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 4 (3.5%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 3 (2.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 16 (13.9%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell -\pard\intbl\qc\fs18 3 (15.8%) \cell -\pard\intbl\qc\fs18 10 (15.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 7 (6.1%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 3 (4.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 5 (4.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 4 (6.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (4.3%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 2 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 15 (13.0%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (15.8%) \cell -\pard\intbl\qc\fs18 11 (16.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 10 (8.7%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 7 (10.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 4 (3.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 2 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 2 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 9 (7.8%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 7 (10.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 7 (6.1%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 (9.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (2.6%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 8 (7.0%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 3 (21.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (6.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 6 (5.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (6.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (1.7%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 4 (3.5%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 3 (2.6%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 2 (1.7%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 3 (2.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 3 (2.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (7.1%) \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 1 (0.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 1 (0.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (0.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2126 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3566 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6309 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7749 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (0.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.5%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2126 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3566 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5006 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6309 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7749 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2126 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3566 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae22apart4/tsfae22apart4of4.rtf b/tests/testthat/_snaps/tsfae22apart4/tsfae22apart4of4.rtf deleted file mode 100755 index 09273c47..00000000 --- a/tests/testthat/_snaps/tsfae22apart4/tsfae22apart4of4.rtf +++ /dev/null @@ -1,1044 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2137 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3633 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE22apart4of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2137 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3633 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3633 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4987 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6340 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7693 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\pard\intbl\qc\fs18 \keepn\trhdr Race \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3633 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4987 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6340 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7693 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr White \cell -\pard\intbl\qc\fs18 \keepn\trhdr Black \cell -\pard\intbl\qc\fs18 \keepn\trhdr Asian \cell -\pard\intbl\qc\fs18 \keepn\trhdr Other \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 32 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 27 (52.9%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 4 (80.0%) \cell -\pard\intbl\qc\fs18 15 (46.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 11 (21.6%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 6 (18.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 1 (3.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 11 (21.6%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 6 (18.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 1 (3.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 1 (3.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 3 (9.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (9.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 7 (13.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 4 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2137 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3633 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4987 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6340 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7693 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2137 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3633 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2137 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3633 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4987 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6340 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7693 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae22bpart2/tsfae22bpart2of2.rtf b/tests/testthat/_snaps/tsfae22bpart2/tsfae22bpart2of2.rtf deleted file mode 100755 index 1beadc06..00000000 --- a/tests/testthat/_snaps/tsfae22bpart2/tsfae22bpart2of2.rtf +++ /dev/null @@ -1,1174 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2146 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3412 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4567 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5723 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6878 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8034 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE22bpart2of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2146 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3412 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4567 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5723 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6878 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8034 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx3412 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx4567 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5723 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx6878 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx8034 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4567 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8034 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Sex \cell -\pard\intbl\qc\fs18 \keepn\trhdr Sex \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Sex \cell -\pard\intbl\qc\fs18 \keepn\trhdr Sex \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3412 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4567 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6878 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8034 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr Male \cell -\pard\intbl\qc\fs18 \keepn\trhdr Female \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr Male \cell -\pard\intbl\qc\fs18 \keepn\trhdr Female \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 63 \cell -\pard\intbl\qc\fs18 63 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 23 \cell -\pard\intbl\qc\fs18 36 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 106 (84.1%) \cell -\pard\intbl\qc\fs18 55 (87.3%) \cell -\pard\intbl\qc\fs18 51 (81.0%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\pard\intbl\qc\fs18 12 (52.2%) \cell -\pard\intbl\qc\fs18 21 (58.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 56 (44.4%) \cell -\pard\intbl\qc\fs18 32 (50.8%) \cell -\pard\intbl\qc\fs18 24 (38.1%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 5 (21.7%) \cell -\pard\intbl\qc\fs18 10 (27.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 18 (28.6%) \cell -\pard\intbl\qc\fs18 16 (25.4%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 1 (4.3%) \cell -\pard\intbl\qc\fs18 5 (13.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 10 (15.9%) \cell -\pard\intbl\qc\fs18 10 (15.9%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 2 (8.7%) \cell -\pard\intbl\qc\fs18 4 (11.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 9 (14.3%) \cell -\pard\intbl\qc\fs18 5 (7.9%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2 (8.7%) \cell -\pard\intbl\qc\fs18 2 (5.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 9 (14.3%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell -\pard\intbl\qc\fs18 28 (44.4%) \cell -\pard\intbl\qc\fs18 26 (41.3%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 5 (21.7%) \cell -\pard\intbl\qc\fs18 8 (22.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 18 (28.6%) \cell -\pard\intbl\qc\fs18 13 (20.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 1 (4.3%) \cell -\pard\intbl\qc\fs18 3 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 14 (22.2%) \cell -\pard\intbl\qc\fs18 7 (11.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (4.3%) \cell -\pard\intbl\qc\fs18 1 (2.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 6 (9.5%) \cell -\pard\intbl\qc\fs18 9 (14.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 6 (9.5%) \cell -\pard\intbl\qc\fs18 5 (7.9%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 3 (13.0%) \cell -\pard\intbl\qc\fs18 2 (5.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 5 (7.9%) \cell -\pard\intbl\qc\fs18 5 (7.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 16 (25.4%) \cell -\pard\intbl\qc\fs18 10 (15.9%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (8.7%) \cell -\pard\intbl\qc\fs18 1 (2.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 12 (19.0%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (4.3%) \cell -\pard\intbl\qc\fs18 1 (2.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (4.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 12 (19.0%) \cell -\pard\intbl\qc\fs18 6 (9.5%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2 (8.7%) \cell -\pard\intbl\qc\fs18 2 (5.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 6 (9.5%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 5 (7.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (8.7%) \cell -\pard\intbl\qc\fs18 1 (2.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 11 (17.5%) \cell -\pard\intbl\qc\fs18 6 (9.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 8 (12.7%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 6 (9.5%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 3 (13.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (4.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (8.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 4 (6.3%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 2 (8.7%) \cell -\pard\intbl\qc\fs18 5 (13.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 2 (8.7%) \cell -\pard\intbl\qc\fs18 3 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2146 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3412 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4567 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5723 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6878 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8034 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2146 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3412 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4567 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5723 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6878 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8034 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2146 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3412 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4567 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5723 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6878 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8034 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae22cpart1/tsfae22cpart1of4.rtf b/tests/testthat/_snaps/tsfae22cpart1/tsfae22cpart1of4.rtf deleted file mode 100755 index d95a581e..00000000 --- a/tests/testthat/_snaps/tsfae22cpart1/tsfae22cpart1of4.rtf +++ /dev/null @@ -1,914 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2134 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7302 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE22cpart1of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2134 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7302 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7302 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7302 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Age (years) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Age (years) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Age (years) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3857 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5579 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7302 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?18 to <65 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?65 to <75 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?75 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 29 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 8 (100.0%) \cell -\pard\intbl\qc\fs18 14 (87.5%) \cell -\pard\intbl\qc\fs18 29 (100.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 7 (43.8%) \cell -\pard\intbl\qc\fs18 18 (62.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 6 (37.5%) \cell -\pard\intbl\qc\fs18 10 (34.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 7 (24.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 6 (75.0%) \cell -\pard\intbl\qc\fs18 6 (37.5%) \cell -\pard\intbl\qc\fs18 11 (37.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 5 (31.2%) \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 3 (18.8%) \cell -\pard\intbl\qc\fs18 9 (31.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 7 (24.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 9 (31.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 6 (20.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (13.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2134 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3857 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5579 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7302 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2134 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7302 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2134 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3857 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5579 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7302 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae22cpart3/tsfae22cpart3of4.rtf b/tests/testthat/_snaps/tsfae22cpart3/tsfae22cpart3of4.rtf deleted file mode 100755 index 9a89eccc..00000000 --- a/tests/testthat/_snaps/tsfae22cpart3/tsfae22cpart3of4.rtf +++ /dev/null @@ -1,914 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2158 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3996 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5833 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7511 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE22cpart3of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2158 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3996 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5833 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7511 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3996 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5833 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7511 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5833 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7511 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Age (years) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Age (years) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Age (years) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3996 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5833 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7511 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?18 to <65 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?65 to <75 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?75 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 13 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 80 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 106 (84.1%) \cell -\pard\intbl\qc\fs18 13 (100.0%) \cell -\pard\intbl\qc\fs18 29 (87.9%) \cell -\pard\intbl\qc\fs18 64 (80.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 56 (44.4%) \cell -\pard\intbl\qc\fs18 6 (46.2%) \cell -\pard\intbl\qc\fs18 12 (36.4%) \cell -\pard\intbl\qc\fs18 38 (47.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 5 (38.5%) \cell -\pard\intbl\qc\fs18 9 (27.3%) \cell -\pard\intbl\qc\fs18 20 (25.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 4 (30.8%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\pard\intbl\qc\fs18 12 (15.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 11 (13.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 8 (10.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 7 (8.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell -\pard\intbl\qc\fs18 10 (76.9%) \cell -\pard\intbl\qc\fs18 13 (39.4%) \cell -\pard\intbl\qc\fs18 31 (38.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 7 (53.8%) \cell -\pard\intbl\qc\fs18 10 (30.3%) \cell -\pard\intbl\qc\fs18 14 (17.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 6 (46.2%) \cell -\pard\intbl\qc\fs18 5 (15.2%) \cell -\pard\intbl\qc\fs18 10 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 3 (23.1%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\pard\intbl\qc\fs18 8 (10.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 9 (11.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 7 (8.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 2 (15.4%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 7 (21.2%) \cell -\pard\intbl\qc\fs18 18 (22.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 6 (18.2%) \cell -\pard\intbl\qc\fs18 9 (11.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 5 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\pard\intbl\qc\fs18 13 (16.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 14 (17.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 8 (10.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 2 (15.4%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 5 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 5 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (15.4%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 6 (7.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 5 (6.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (3.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2158 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3996 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5833 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2158 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3996 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5833 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7511 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2158 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3996 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5833 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae22cpart4/tsfae22cpart4of4.rtf b/tests/testthat/_snaps/tsfae22cpart4/tsfae22cpart4of4.rtf deleted file mode 100755 index 5292e0c2..00000000 --- a/tests/testthat/_snaps/tsfae22cpart4/tsfae22cpart4of4.rtf +++ /dev/null @@ -1,914 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2147 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3951 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5582 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7386 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE22cpart4of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2147 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3951 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5582 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7386 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3951 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5582 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7386 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5582 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7386 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Age (years) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Age (years) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Age (years) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3951 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5582 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7386 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?18 to <65 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?65 to <75 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805?75 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 33 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 AE \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 10 (52.6%) \cell -\pard\intbl\qc\fs18 21 (63.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 4 (21.1%) \cell -\pard\intbl\qc\fs18 9 (27.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 5 (15.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 6 (31.6%) \cell -\pard\intbl\qc\fs18 6 (18.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (15.8%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (9.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (5.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7 (21.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 (15.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2147 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3951 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5582 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7386 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2147 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3951 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5582 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7386 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2147 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3951 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5582 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7386 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae23a/tsfae23a.rtf b/tests/testthat/_snaps/tsfae23a/tsfae23a.rtf deleted file mode 100755 index c9012074..00000000 --- a/tests/testthat/_snaps/tsfae23a/tsfae23a.rtf +++ /dev/null @@ -1,340 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4330 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5832 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7511 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE23a:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2828 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4330 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5832 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7511 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related SAE \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 RASH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5832 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7511 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4330 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5832 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7511 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5832 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7511 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae23c/tsfae23c.rtf b/tests/testthat/_snaps/tsfae23c/tsfae23c.rtf deleted file mode 100755 index bd25d90e..00000000 --- a/tests/testthat/_snaps/tsfae23c/tsfae23c.rtf +++ /dev/null @@ -1,228 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2878 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4456 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6034 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7611 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE23c:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2878 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4456 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6034 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7611 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related AE leading to discontinuation \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 RASH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2878 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4456 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6034 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7611 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae23d/tsfae23d.rtf b/tests/testthat/_snaps/tsfae23d/tsfae23d.rtf deleted file mode 100755 index 91c2bfd1..00000000 --- a/tests/testthat/_snaps/tsfae23d/tsfae23d.rtf +++ /dev/null @@ -1,340 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2847 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4554 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5937 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7644 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE23d:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2847 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4554 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5937 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7644 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 related non-serious AE \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 COUGH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 RASH \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2847 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4554 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5937 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7644 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2847 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4554 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5937 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7644 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2847 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4554 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5937 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7644 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae24a/tsfae24a.rtf b/tests/testthat/_snaps/tsfae24a/tsfae24a.rtf deleted file mode 100755 index 22e0da82..00000000 --- a/tests/testthat/_snaps/tsfae24a/tsfae24a.rtf +++ /dev/null @@ -1,148 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE24a:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2828 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7069 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Severity \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Severe \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Moderate \cell -\pard\intbl\qc\fs18 29 (54.7%) \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Mild \cell -\pard\intbl\qc\fs18 22 (41.5%) \cell -\pard\intbl\qc\fs18 20 (27.4%) \cell -\pard\intbl\qc\fs18 22 (37.3%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae24c/tsfae24c.rtf b/tests/testthat/_snaps/tsfae24c/tsfae24c.rtf deleted file mode 100755 index 338678f3..00000000 --- a/tests/testthat/_snaps/tsfae24c/tsfae24c.rtf +++ /dev/null @@ -1,1138 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11193 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE24c:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2858 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx7859 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx11193 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr AEs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr AEs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr AEs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Related AEs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Related AEs \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr Related AEs \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 8 (13.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SOMNOLENCE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ABDOMINAL PAIN \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ARTHRALGIA \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 WOUND HAEMORRHAGE \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ANXIETY \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11193 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae24d/tsfae24d.rtf b/tests/testthat/_snaps/tsfae24d/tsfae24d.rtf deleted file mode 100755 index 0eb278d8..00000000 --- a/tests/testthat/_snaps/tsfae24d/tsfae24d.rtf +++ /dev/null @@ -1,1060 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2842 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4060 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5278 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6496 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7714 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10266 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11483 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE24d:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2842 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4060 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5278 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6496 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7714 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10266 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11483 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx4060 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5278 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx6496 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7714 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx9048 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx10266 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx11483 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805? Grade 3 AEs \cell -\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805? Grade 3 AEs \cell -\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805? Grade 3 AEs \cell -\pard\intbl\qc\fs18 \keepn\trhdr AEs \cell -\pard\intbl\qc\fs18 \keepn\trhdr \u8805? Grade 3 AEs \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 44 (83.0%) \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 43 (58.9%) \cell -\pard\intbl\qc\fs18 106 (84.1%) \cell -\pard\intbl\qc\fs18 87 (69.0%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\pard\intbl\qc\fs18 23 (39.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 23 (31.5%) \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell -\pard\intbl\qc\fs18 43 (34.1%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 9 (15.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 31 (24.6%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 21 (16.7%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 18 (34.0%) \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 17 (23.3%) \cell -\pard\intbl\qc\fs18 56 (44.4%) \cell -\pard\intbl\qc\fs18 35 (27.8%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 34 (27.0%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 20 (15.9%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (24.5%) \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 10 (18.9%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 17 (13.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2842 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4060 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5278 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6496 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7714 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9048 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10266 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11483 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2842 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4060 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5278 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6496 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7714 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9048 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10266 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11483 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2842 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4060 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5278 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6496 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7714 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9048 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10266 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11483 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae24fpart2/tsfae24fpart2of3.rtf b/tests/testthat/_snaps/tsfae24fpart2/tsfae24fpart2of3.rtf deleted file mode 100755 index 6af95393..00000000 --- a/tests/testthat/_snaps/tsfae24fpart2/tsfae24fpart2of3.rtf +++ /dev/null @@ -1,994 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11193 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE24fpart2of3:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2858 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11193 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11193 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4525 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6192 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11193 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr Within 3 months \cell -\pard\intbl\qc\fs18 \keepn\trhdr 4 to 6 months \cell -\pard\intbl\qc\fs18 \keepn\trhdr 7 to 9 months \cell -\pard\intbl\qc\fs18 \keepn\trhdr 10 to 12 months \cell -\pard\intbl\qc\fs18 \keepn\trhdr Beyond 13 months \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 55 \cell -\pard\intbl\qc\fs18 39 \cell -\pard\intbl\qc\fs18 24 \cell -\pard\intbl\qc\fs18 12 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 14 (25.5%) \cell -\pard\intbl\qc\fs18 10 (25.6%) \cell -\pard\intbl\qc\fs18 10 (41.7%) \cell -\pard\intbl\qc\fs18 8 (66.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 26 (35.6%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 7 (12.7%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 6 (25.0%) \cell -\pard\intbl\qc\fs18 4 (33.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 3 (5.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (16.7%) \cell -\pard\intbl\qc\fs18 3 (25.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (8.3%) \cell -\pard\intbl\qc\fs18 1 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.6%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (5.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (12.5%) \cell -\pard\intbl\qc\fs18 1 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 1 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 9 (16.4%) \cell -\pard\intbl\qc\fs18 5 (12.8%) \cell -\pard\intbl\qc\fs18 4 (16.7%) \cell -\pard\intbl\qc\fs18 5 (41.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 5 (9.1%) \cell -\pard\intbl\qc\fs18 3 (7.7%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 3 (25.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 2 (3.6%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 2 (16.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (5.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 2 (16.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 1 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.6%) \cell -\pard\intbl\qc\fs18 3 (7.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (16.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.6%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (5.5%) \cell -\pard\intbl\qc\fs18 4 (10.3%) \cell -\pard\intbl\qc\fs18 3 (12.5%) \cell -\pard\intbl\qc\fs18 2 (16.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.6%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 2 (8.3%) \cell -\pard\intbl\qc\fs18 2 (16.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (16.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.8%) \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.8%) \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 2 (16.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.8%) \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (3.6%) \cell -\pard\intbl\qc\fs18 3 (7.7%) \cell -\pard\intbl\qc\fs18 2 (8.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.8%) \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4525 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6192 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9526 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11193 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11193 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4525 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6192 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9526 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11193 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae24fpart3/tsfae24fpart3of3.rtf b/tests/testthat/_snaps/tsfae24fpart3/tsfae24fpart3of3.rtf deleted file mode 100755 index f0fe34f9..00000000 --- a/tests/testthat/_snaps/tsfae24fpart3/tsfae24fpart3of3.rtf +++ /dev/null @@ -1,994 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2813 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4603 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6223 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7672 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9292 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11082 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE24fpart3of3:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2813 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4603 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6223 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7672 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9292 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11082 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4603 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6223 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7672 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9292 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11082 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2813 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4603 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6223 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7672 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9292 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11082 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr Within 3 months \cell -\pard\intbl\qc\fs18 \keepn\trhdr 4 to 6 months \cell -\pard\intbl\qc\fs18 \keepn\trhdr 7 to 9 months \cell -\pard\intbl\qc\fs18 \keepn\trhdr 10 to 12 months \cell -\pard\intbl\qc\fs18 \keepn\trhdr Beyond 13 months \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set: Safety \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 44 \cell -\pard\intbl\qc\fs18 34 \cell -\pard\intbl\qc\fs18 22 \cell -\pard\intbl\qc\fs18 8 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell -\pard\intbl\qc\fs18 9 (15.3%) \cell -\pard\intbl\qc\fs18 4 (9.1%) \cell -\pard\intbl\qc\fs18 7 (20.6%) \cell -\pard\intbl\qc\fs18 10 (45.5%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 3 (6.8%) \cell -\pard\intbl\qc\fs18 4 (11.8%) \cell -\pard\intbl\qc\fs18 3 (13.6%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PRURITUS \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (4.5%) \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ERYTHEMA \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (2.3%) \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERHIDROSIS \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 RASH \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN IRRITATION \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLISTER \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (11.8%) \cell -\pard\intbl\qc\fs18 5 (22.7%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE PRURITUS \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE ERYTHEMA \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE IRRITATION \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 FATIGUE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE DERMATITIS \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 APPLICATION SITE VESICLES \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 OEDEMA PERIPHERAL \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (9.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIZZINESS \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HEADACHE \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SYNCOPE \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SINUS BRADYCARDIA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 MYOCARDIAL INFARCTION \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ATRIAL FIBRILLATION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (2.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (9.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NAUSEA \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VOMITING \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 DIARRHOEA \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (2.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 3 (13.6%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 1 (4.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 UPPER RESPIRATORY TRACT INFECTION \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (9.1%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.3%) \cell -\pard\intbl\qc\fs18 2 (5.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 COUGH \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASAL CONGESTION \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (2.3%) \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2813 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4603 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6223 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7672 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9292 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11082 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BACK PAIN \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2813 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4603 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6223 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7672 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9292 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11082 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2813 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4603 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6223 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7672 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9292 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11082 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfdth01/tsfdth01.rtf b/tests/testthat/_snaps/tsfdth01/tsfdth01.rtf old mode 100755 new mode 100644 index 23bf7707..4c9f79d6 --- a/tests/testthat/_snaps/tsfdth01/tsfdth01.rtf +++ b/tests/testthat/_snaps/tsfdth01/tsfdth01.rtf @@ -3,12 +3,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3284 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4753 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6221 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7690 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10196 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4156 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5488 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6821 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8154 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10428 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFDTH01:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,12 +21,12 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2852 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3284 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4753 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6221 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7690 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10196 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4156 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5488 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6821 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8154 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10428 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -39,35 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Deaths \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10196 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Cause of Death, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10428 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Primary Cause of Death, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -75,66 +75,66 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Total deaths \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sudden death \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -147,66 +147,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Deaths within 30 days of last dose \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1.4 (-3.7, 6.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sudden death \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1.5 (-1.4, 4.4) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -219,66 +219,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Deaths beyond 30 days of last dose \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.8, 5.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sudden death \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sudden death \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -291,66 +291,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Deaths within 60 days of first dose \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 0.4 (-4.5, 5.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sudden death \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.6, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3284 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4753 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6221 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7690 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10196 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4156 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5488 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6821 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8154 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10428 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sudden death \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3284 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4753 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6221 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7690 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10196 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4156 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5488 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6821 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8154 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10428 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -363,12 +363,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3284 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4753 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6221 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7690 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10196 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4156 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5488 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6821 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8154 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10428 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfecg01/tsfecg01.rtf b/tests/testthat/_snaps/tsfecg01/tsfecg01.rtf new file mode 100644 index 00000000..b7dffd44 --- /dev/null +++ b/tests/testthat/_snaps/tsfecg01/tsfecg01.rtf @@ -0,0 +1,10070 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2837 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5303 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7954 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10297 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG01:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2837 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5303 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7954 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10297 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 317.9 (187.74) \cell +\pard\intbl\qc\fs18 318.8 (157.04) \cell +\pard\intbl\qc\fs18 318.3 (174.42) \cell +\pard\intbl\qc\fs18 266.3 (166.19) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 339.0 (2, 591) \cell +\pard\intbl\qc\fs18 339.0 (6, 576) \cell +\pard\intbl\qc\fs18 339.0 (2, 591) \cell +\pard\intbl\qc\fs18 264.5 (13, 591) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 299.0 (191.78) \cell +\pard\intbl\qc\fs18 270.5 (187.40) \cell +\pard\intbl\qc\fs18 286.6 (189.60) \cell +\pard\intbl\qc\fs18 274.2 (180.75) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 263.0 (1, 596) \cell +\pard\intbl\qc\fs18 265.0 (8, 592) \cell +\pard\intbl\qc\fs18 265.0 (1, 596) \cell +\pard\intbl\qc\fs18 251.5 (1, 600) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 322.2 (185.73) \cell +\pard\intbl\qc\fs18 318.8 (157.04) \cell +\pard\intbl\qc\fs18 320.7 (173.09) \cell +\pard\intbl\qc\fs18 266.0 (168.79) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -23.2 (267.98) \cell +\pard\intbl\qc\fs18 -48.3 (233.58) \cell +\pard\intbl\qc\fs18 -34.1 (252.81) \cell +\pard\intbl\qc\fs18 8.2 (232.53) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -19.0 (-551, 547) \cell +\pard\intbl\qc\fs18 -24.0 (-515, 411) \cell +\pard\intbl\qc\fs18 -24.0 (-551, 547) \cell +\pard\intbl\qc\fs18 -8.5 (-357, 525) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -31.4 (-119.1, 56.2) \cell +\pard\intbl\qc\fs18 -56.5 (-143.8, 30.9) \cell +\pard\intbl\qc\fs18 -42.4 (-116.8, 32.1) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 331.9 (184.87) \cell +\pard\intbl\qc\fs18 326.6 (181.76) \cell +\pard\intbl\qc\fs18 329.2 (182.33) \cell +\pard\intbl\qc\fs18 299.1 (170.40) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 350.0 (4, 595) \cell +\pard\intbl\qc\fs18 376.0 (1, 580) \cell +\pard\intbl\qc\fs18 371.5 (1, 595) \cell +\pard\intbl\qc\fs18 302.0 (23, 597) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 311.8 (182.63) \cell +\pard\intbl\qc\fs18 318.8 (157.04) \cell +\pard\intbl\qc\fs18 315.4 (168.94) \cell +\pard\intbl\qc\fs18 264.8 (169.91) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 20.1 (276.31) \cell +\pard\intbl\qc\fs18 7.8 (238.54) \cell +\pard\intbl\qc\fs18 13.7 (256.07) \cell +\pard\intbl\qc\fs18 34.3 (232.82) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.0 (-487, 516) \cell +\pard\intbl\qc\fs18 31.0 (-476, 496) \cell +\pard\intbl\qc\fs18 8.0 (-487, 516) \cell +\pard\intbl\qc\fs18 18.0 (-568, 526) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -14.2 (-113.8, 85.4) \cell +\pard\intbl\qc\fs18 -26.5 (-115.2, 62.3) \cell +\pard\intbl\qc\fs18 -20.6 (-98.6, 57.5) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 263.4 (167.89) \cell +\pard\intbl\qc\fs18 249.0 (162.61) \cell +\pard\intbl\qc\fs18 255.8 (164.34) \cell +\pard\intbl\qc\fs18 293.0 (192.86) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 268.0 (3, 550) \cell +\pard\intbl\qc\fs18 224.0 (7, 538) \cell +\pard\intbl\qc\fs18 252.0 (3, 550) \cell +\pard\intbl\qc\fs18 298.0 (4, 596) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 322.6 (177.16) \cell +\pard\intbl\qc\fs18 312.9 (156.16) \cell +\pard\intbl\qc\fs18 317.5 (165.51) \cell +\pard\intbl\qc\fs18 270.8 (173.65) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -59.3 (234.40) \cell +\pard\intbl\qc\fs18 -64.0 (266.92) \cell +\pard\intbl\qc\fs18 -61.8 (250.69) \cell +\pard\intbl\qc\fs18 22.2 (265.16) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -50.0 (-500, 478) \cell +\pard\intbl\qc\fs18 -129.0 (-452, 461) \cell +\pard\intbl\qc\fs18 -95.0 (-500, 478) \cell +\pard\intbl\qc\fs18 35.0 (-489, 547) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -81.5 (-182.5, 19.5) \cell +\pard\intbl\qc\fs18 -86.2 (-191.1, 18.7) \cell +\pard\intbl\qc\fs18 -84.0 (-172.3, 4.3) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 346.9 (184.65) \cell +\pard\intbl\qc\fs18 294.9 (169.62) \cell +\pard\intbl\qc\fs18 320.9 (178.07) \cell +\pard\intbl\qc\fs18 298.3 (175.52) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 416.0 (0, 582) \cell +\pard\intbl\qc\fs18 327.0 (23, 594) \cell +\pard\intbl\qc\fs18 345.0 (0, 594) \cell +\pard\intbl\qc\fs18 290.5 (4, 596) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 322.3 (176.52) \cell +\pard\intbl\qc\fs18 315.8 (159.03) \cell +\pard\intbl\qc\fs18 319.1 (166.94) \cell +\pard\intbl\qc\fs18 268.0 (170.57) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 24.6 (261.19) \cell +\pard\intbl\qc\fs18 -20.9 (277.39) \cell +\pard\intbl\qc\fs18 1.9 (268.63) \cell +\pard\intbl\qc\fs18 30.3 (278.83) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 65.0 (-513, 477) \cell +\pard\intbl\qc\fs18 -38.0 (-487, 560) \cell +\pard\intbl\qc\fs18 39.5 (-513, 560) \cell +\pard\intbl\qc\fs18 -8.5 (-467, 543) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -5.7 (-119.0, 107.5) \cell +\pard\intbl\qc\fs18 -51.2 (-168.4, 65.9) \cell +\pard\intbl\qc\fs18 -28.5 (-126.0, 69.1) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 317.3 (187.61) \cell +\pard\intbl\qc\fs18 307.8 (159.04) \cell +\pard\intbl\qc\fs18 312.5 (172.49) \cell +\pard\intbl\qc\fs18 326.4 (172.18) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 310.0 (2, 590) \cell +\pard\intbl\qc\fs18 309.0 (45, 589) \cell +\pard\intbl\qc\fs18 309.0 (2, 590) \cell +\pard\intbl\qc\fs18 328.5 (8, 574) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 316.8 (179.58) \cell +\pard\intbl\qc\fs18 316.9 (158.96) \cell +\pard\intbl\qc\fs18 316.8 (168.18) \cell +\pard\intbl\qc\fs18 267.9 (172.39) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.5 (232.95) \cell +\pard\intbl\qc\fs18 -9.1 (174.45) \cell +\pard\intbl\qc\fs18 -4.3 (203.90) \cell +\pard\intbl\qc\fs18 58.5 (209.39) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 28.0 (-459, 540) \cell +\pard\intbl\qc\fs18 -21.0 (-367, 302) \cell +\pard\intbl\qc\fs18 12.0 (-459, 540) \cell +\pard\intbl\qc\fs18 51.5 (-378, 512) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -57.9 (-157.9, 42.1) \cell +\pard\intbl\qc\fs18 -67.5 (-151.6, 16.5) \cell +\pard\intbl\qc\fs18 -62.8 (-140.0, 14.5) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 289.2 (170.92) \cell +\pard\intbl\qc\fs18 314.1 (158.47) \cell +\pard\intbl\qc\fs18 301.4 (163.88) \cell +\pard\intbl\qc\fs18 317.8 (157.93) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 303.5 (49, 540) \cell +\pard\intbl\qc\fs18 317.0 (34, 597) \cell +\pard\intbl\qc\fs18 305.0 (34, 597) \cell +\pard\intbl\qc\fs18 338.0 (50, 600) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 322.3 (174.59) \cell +\pard\intbl\qc\fs18 310.1 (162.13) \cell +\pard\intbl\qc\fs18 316.3 (167.14) \cell +\pard\intbl\qc\fs18 267.9 (172.39) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -33.1 (252.90) \cell +\pard\intbl\qc\fs18 4.0 (237.75) \cell +\pard\intbl\qc\fs18 -14.9 (244.02) \cell +\pard\intbl\qc\fs18 49.9 (273.43) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -72.0 (-472, 412) \cell +\pard\intbl\qc\fs18 -29.0 (-529, 575) \cell +\pard\intbl\qc\fs18 -38.0 (-529, 575) \cell +\pard\intbl\qc\fs18 66.0 (-521, 505) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -83.0 (-207.0, 41.0) \cell +\pard\intbl\qc\fs18 -45.9 (-166.7, 75.0) \cell +\pard\intbl\qc\fs18 -64.8 (-166.8, 37.2) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 265.6 (180.94) \cell +\pard\intbl\qc\fs18 311.6 (191.85) \cell +\pard\intbl\qc\fs18 289.1 (185.84) \cell +\pard\intbl\qc\fs18 277.2 (159.88) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 234.0 (27, 583) \cell +\pard\intbl\qc\fs18 323.5 (18, 598) \cell +\pard\intbl\qc\fs18 258.0 (18, 598) \cell +\pard\intbl\qc\fs18 259.0 (3, 582) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 357.7 (162.37) \cell +\pard\intbl\qc\fs18 288.8 (170.18) \cell +\pard\intbl\qc\fs18 322.5 (168.07) \cell +\pard\intbl\qc\fs18 272.3 (171.56) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -92.1 (259.93) \cell +\pard\intbl\qc\fs18 22.8 (248.72) \cell +\pard\intbl\qc\fs18 -33.3 (257.85) \cell +\pard\intbl\qc\fs18 4.9 (221.43) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -146.0 (-420, 572) \cell +\pard\intbl\qc\fs18 79.5 (-498, 366) \cell +\pard\intbl\qc\fs18 -50.0 (-498, 572) \cell +\pard\intbl\qc\fs18 1.0 (-385, 444) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -97.1 (-229.8, 35.6) \cell +\pard\intbl\qc\fs18 17.9 (-107.9, 143.7) \cell +\pard\intbl\qc\fs18 -38.3 (-139.5, 62.9) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 378.8 (169.70) \cell +\pard\intbl\qc\fs18 320.4 (180.93) \cell +\pard\intbl\qc\fs18 348.9 (175.83) \cell +\pard\intbl\qc\fs18 289.8 (184.36) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 418.5 (68, 594) \cell +\pard\intbl\qc\fs18 333.0 (10, 599) \cell +\pard\intbl\qc\fs18 369.0 (10, 599) \cell +\pard\intbl\qc\fs18 275.0 (16, 598) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 350.8 (163.34) \cell +\pard\intbl\qc\fs18 285.3 (173.57) \cell +\pard\intbl\qc\fs18 317.2 (169.80) \cell +\pard\intbl\qc\fs18 276.6 (170.50) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 28.0 (215.59) \cell +\pard\intbl\qc\fs18 35.1 (259.47) \cell +\pard\intbl\qc\fs18 31.6 (236.12) \cell +\pard\intbl\qc\fs18 13.2 (240.92) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 63.5 (-381, 353) \cell +\pard\intbl\qc\fs18 51.0 (-506, 423) \cell +\pard\intbl\qc\fs18 60.0 (-506, 423) \cell +\pard\intbl\qc\fs18 -5.0 (-384, 520) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 14.8 (-108.6, 138.2) \cell +\pard\intbl\qc\fs18 21.9 (-115.7, 159.5) \cell +\pard\intbl\qc\fs18 18.4 (-86.4, 123.3) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 RR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 281.73 (167.877) \cell +\pard\intbl\qc\fs18 345.75 (152.862) \cell +\pard\intbl\qc\fs18 309.40 (164.006) \cell +\pard\intbl\qc\fs18 304.09 (156.891) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 306.00 (5.0, 596.0) \cell +\pard\intbl\qc\fs18 348.00 (53.0, 598.0) \cell +\pard\intbl\qc\fs18 318.50 (5.0, 598.0) \cell +\pard\intbl\qc\fs18 321.00 (1.0, 575.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 338.91 (158.188) \cell +\pard\intbl\qc\fs18 290.35 (150.606) \cell +\pard\intbl\qc\fs18 317.74 (156.151) \cell +\pard\intbl\qc\fs18 292.27 (150.866) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 361.00 (27.0, 597.0) \cell +\pard\intbl\qc\fs18 319.00 (19.0, 537.0) \cell +\pard\intbl\qc\fs18 340.00 (19.0, 597.0) \cell +\pard\intbl\qc\fs18 315.00 (29.0, 542.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 284.44 (167.683) \cell +\pard\intbl\qc\fs18 345.75 (152.862) \cell +\pard\intbl\qc\fs18 311.16 (163.583) \cell +\pard\intbl\qc\fs18 300.97 (155.530) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 54.47 (231.167) \cell +\pard\intbl\qc\fs18 -55.39 (219.223) \cell +\pard\intbl\qc\fs18 6.58 (231.630) \cell +\pard\intbl\qc\fs18 -8.69 (222.463) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 65.00 (-456.0, 512.0) \cell +\pard\intbl\qc\fs18 -62.00 (-536.0, 423.0) \cell +\pard\intbl\qc\fs18 18.00 (-536.0, 512.0) \cell +\pard\intbl\qc\fs18 -8.50 (-451.0, 483.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 63.16 (-16.19, 142.52) \cell +\pard\intbl\qc\fs18 -46.70 (-129.40, 36.00) \cell +\pard\intbl\qc\fs18 15.27 (-54.87, 85.42) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 316.43 (174.709) \cell +\pard\intbl\qc\fs18 311.47 (172.210) \cell +\pard\intbl\qc\fs18 313.85 (172.534) \cell +\pard\intbl\qc\fs18 303.59 (162.066) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 329.00 (14.0, 597.0) \cell +\pard\intbl\qc\fs18 296.00 (3.0, 595.0) \cell +\pard\intbl\qc\fs18 308.50 (3.0, 597.0) \cell +\pard\intbl\qc\fs18 276.00 (40.0, 597.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 294.96 (171.626) \cell +\pard\intbl\qc\fs18 345.75 (152.862) \cell +\pard\intbl\qc\fs18 321.39 (163.290) \cell +\pard\intbl\qc\fs18 304.97 (153.573) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 21.47 (242.175) \cell +\pard\intbl\qc\fs18 -34.27 (247.959) \cell +\pard\intbl\qc\fs18 -7.54 (245.538) \cell +\pard\intbl\qc\fs18 -1.38 (184.308) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 19.00 (-469.0, 487.0) \cell +\pard\intbl\qc\fs18 -42.00 (-457.0, 531.0) \cell +\pard\intbl\qc\fs18 5.50 (-469.0, 531.0) \cell +\pard\intbl\qc\fs18 4.00 (-358.0, 396.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 22.85 (-61.64, 107.33) \cell +\pard\intbl\qc\fs18 -32.90 (-116.29, 50.50) \cell +\pard\intbl\qc\fs18 -6.16 (-73.80, 61.48) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 281.62 (186.977) \cell +\pard\intbl\qc\fs18 246.53 (151.252) \cell +\pard\intbl\qc\fs18 263.09 (168.989) \cell +\pard\intbl\qc\fs18 308.84 (174.844) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 254.50 (22.0, 596.0) \cell +\pard\intbl\qc\fs18 210.00 (4.0, 582.0) \cell +\pard\intbl\qc\fs18 212.00 (4.0, 596.0) \cell +\pard\intbl\qc\fs18 281.00 (14.0, 597.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 302.24 (167.276) \cell +\pard\intbl\qc\fs18 338.19 (155.562) \cell +\pard\intbl\qc\fs18 321.22 (161.283) \cell +\pard\intbl\qc\fs18 299.75 (156.904) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -20.62 (269.908) \cell +\pard\intbl\qc\fs18 -91.66 (240.377) \cell +\pard\intbl\qc\fs18 -58.13 (255.768) \cell +\pard\intbl\qc\fs18 9.09 (253.128) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -6.00 (-574.0, 520.0) \cell +\pard\intbl\qc\fs18 -75.00 (-555.0, 518.0) \cell +\pard\intbl\qc\fs18 -67.00 (-574.0, 520.0) \cell +\pard\intbl\qc\fs18 -1.00 (-435.0, 536.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -29.71 (-136.77, 77.35) \cell +\pard\intbl\qc\fs18 -100.75 (-197.84, -3.66) \cell +\pard\intbl\qc\fs18 -67.23 (-153.56, 19.11) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 310.69 (167.832) \cell +\pard\intbl\qc\fs18 334.87 (165.425) \cell +\pard\intbl\qc\fs18 322.78 (165.993) \cell +\pard\intbl\qc\fs18 336.17 (166.056) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 314.00 (13.0, 585.0) \cell +\pard\intbl\qc\fs18 308.00 (4.0, 596.0) \cell +\pard\intbl\qc\fs18 311.00 (4.0, 596.0) \cell +\pard\intbl\qc\fs18 322.50 (3.0, 597.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 305.15 (171.039) \cell +\pard\intbl\qc\fs18 340.72 (153.096) \cell +\pard\intbl\qc\fs18 322.94 (162.249) \cell +\pard\intbl\qc\fs18 304.81 (159.285) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.54 (213.897) \cell +\pard\intbl\qc\fs18 -5.85 (251.692) \cell +\pard\intbl\qc\fs18 -0.15 (232.110) \cell +\pard\intbl\qc\fs18 31.37 (247.553) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -13.00 (-513.0, 547.0) \cell +\pard\intbl\qc\fs18 -9.00 (-531.0, 423.0) \cell +\pard\intbl\qc\fs18 -12.50 (-531.0, 547.0) \cell +\pard\intbl\qc\fs18 33.50 (-448.0, 547.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -25.83 (-122.21, 70.56) \cell +\pard\intbl\qc\fs18 -37.21 (-142.54, 68.12) \cell +\pard\intbl\qc\fs18 -31.52 (-117.25, 54.21) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 306.41 (169.099) \cell +\pard\intbl\qc\fs18 244.94 (179.668) \cell +\pard\intbl\qc\fs18 275.23 (175.998) \cell +\pard\intbl\qc\fs18 321.23 (170.875) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 312.50 (24.0, 573.0) \cell +\pard\intbl\qc\fs18 194.00 (9.0, 600.0) \cell +\pard\intbl\qc\fs18 242.00 (9.0, 600.0) \cell +\pard\intbl\qc\fs18 311.00 (15.0, 584.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 305.18 (172.039) \cell +\pard\intbl\qc\fs18 343.26 (153.383) \cell +\pard\intbl\qc\fs18 324.49 (162.771) \cell +\pard\intbl\qc\fs18 303.65 (161.277) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.24 (210.269) \cell +\pard\intbl\qc\fs18 -98.31 (271.322) \cell +\pard\intbl\qc\fs18 -49.26 (246.531) \cell +\pard\intbl\qc\fs18 17.58 (233.030) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -12.00 (-425.0, 435.0) \cell +\pard\intbl\qc\fs18 -115.00 (-555.0, 458.0) \cell +\pard\intbl\qc\fs18 -62.00 (-555.0, 458.0) \cell +\pard\intbl\qc\fs18 38.50 (-463.0, 500.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -16.35 (-114.58, 81.88) \cell +\pard\intbl\qc\fs18 -115.90 (-229.43, -2.36) \cell +\pard\intbl\qc\fs18 -66.84 (-155.79, 22.10) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 362.32 (163.019) \cell +\pard\intbl\qc\fs18 361.96 (174.910) \cell +\pard\intbl\qc\fs18 362.15 (167.385) \cell +\pard\intbl\qc\fs18 296.73 (154.513) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 373.50 (76.0, 587.0) \cell +\pard\intbl\qc\fs18 410.00 (54.0, 584.0) \cell +\pard\intbl\qc\fs18 380.00 (54.0, 587.0) \cell +\pard\intbl\qc\fs18 290.00 (17.0, 576.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 298.39 (180.456) \cell +\pard\intbl\qc\fs18 316.26 (151.947) \cell +\pard\intbl\qc\fs18 307.16 (165.771) \cell +\pard\intbl\qc\fs18 303.65 (161.277) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 63.93 (255.848) \cell +\pard\intbl\qc\fs18 45.70 (185.218) \cell +\pard\intbl\qc\fs18 54.98 (222.106) \cell +\pard\intbl\qc\fs18 -6.92 (195.250) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 110.00 (-477.0, 519.0) \cell +\pard\intbl\qc\fs18 1.00 (-268.0, 436.0) \cell +\pard\intbl\qc\fs18 67.00 (-477.0, 519.0) \cell +\pard\intbl\qc\fs18 2.50 (-402.0, 423.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 70.85 (-41.84, 183.53) \cell +\pard\intbl\qc\fs18 52.62 (-38.39, 143.63) \cell +\pard\intbl\qc\fs18 61.90 (-19.68, 143.48) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 205.38 (146.258) \cell +\pard\intbl\qc\fs18 296.86 (200.837) \cell +\pard\intbl\qc\fs18 252.19 (180.264) \cell +\pard\intbl\qc\fs18 290.79 (175.658) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 144.00 (21.0, 501.0) \cell +\pard\intbl\qc\fs18 299.50 (10.0, 574.0) \cell +\pard\intbl\qc\fs18 218.00 (10.0, 574.0) \cell +\pard\intbl\qc\fs18 281.00 (4.0, 569.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 293.52 (169.850) \cell +\pard\intbl\qc\fs18 343.41 (151.896) \cell +\pard\intbl\qc\fs18 319.05 (160.967) \cell +\pard\intbl\qc\fs18 303.79 (163.017) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -88.14 (191.528) \cell +\pard\intbl\qc\fs18 -46.55 (263.956) \cell +\pard\intbl\qc\fs18 -66.86 (229.667) \cell +\pard\intbl\qc\fs18 -13.00 (241.611) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -15.00 (-416.0, 196.0) \cell +\pard\intbl\qc\fs18 -20.50 (-548.0, 426.0) \cell +\pard\intbl\qc\fs18 -15.00 (-548.0, 426.0) \cell +\pard\intbl\qc\fs18 -5.00 (-504.0, 568.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -75.14 (-185.07, 34.78) \cell +\pard\intbl\qc\fs18 -33.55 (-167.96, 100.87) \cell +\pard\intbl\qc\fs18 -53.86 (-152.60, 44.88) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 291.25 (141.905) \cell +\pard\intbl\qc\fs18 270.71 (154.632) \cell +\pard\intbl\qc\fs18 280.73 (147.067) \cell +\pard\intbl\qc\fs18 334.88 (174.095) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 281.50 (75.0, 586.0) \cell +\pard\intbl\qc\fs18 278.00 (13.0, 577.0) \cell +\pard\intbl\qc\fs18 278.00 (13.0, 586.0) \cell +\pard\intbl\qc\fs18 355.00 (17.0, 581.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 299.50 (171.982) \cell +\pard\intbl\qc\fs18 343.67 (155.643) \cell +\pard\intbl\qc\fs18 322.12 (163.283) \cell +\pard\intbl\qc\fs18 313.83 (157.264) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -8.25 (217.072) \cell +\pard\intbl\qc\fs18 -72.95 (182.061) \cell +\pard\intbl\qc\fs18 -41.39 (200.068) \cell +\pard\intbl\qc\fs18 21.05 (247.867) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 11.00 (-461.0, 384.0) \cell +\pard\intbl\qc\fs18 -110.00 (-359.0, 254.0) \cell +\pard\intbl\qc\fs18 -54.00 (-461.0, 384.0) \cell +\pard\intbl\qc\fs18 2.00 (-541.0, 523.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -29.30 (-154.53, 95.94) \cell +\pard\intbl\qc\fs18 -94.00 (-205.29, 17.29) \cell +\pard\intbl\qc\fs18 -62.44 (-161.51, 36.63) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QRS Duration, Aggregate (ms) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 303.27 (177.308) \cell +\pard\intbl\qc\fs18 315.31 (163.341) \cell +\pard\intbl\qc\fs18 308.47 (170.798) \cell +\pard\intbl\qc\fs18 307.48 (175.787) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 298.00 (7.0, 600.0) \cell +\pard\intbl\qc\fs18 328.00 (2.0, 598.0) \cell +\pard\intbl\qc\fs18 298.00 (2.0, 600.0) \cell +\pard\intbl\qc\fs18 320.00 (2.0, 600.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 273.30 (160.035) \cell +\pard\intbl\qc\fs18 313.10 (173.023) \cell +\pard\intbl\qc\fs18 290.65 (166.276) \cell +\pard\intbl\qc\fs18 286.68 (168.987) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 248.00 (27.0, 594.0) \cell +\pard\intbl\qc\fs18 376.00 (11.0, 591.0) \cell +\pard\intbl\qc\fs18 292.00 (11.0, 594.0) \cell +\pard\intbl\qc\fs18 318.50 (2.0, 583.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 302.14 (178.422) \cell +\pard\intbl\qc\fs18 315.31 (163.341) \cell +\pard\intbl\qc\fs18 307.88 (171.410) \cell +\pard\intbl\qc\fs18 301.06 (174.624) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -28.83 (266.438) \cell +\pard\intbl\qc\fs18 -2.22 (232.076) \cell +\pard\intbl\qc\fs18 -17.23 (251.335) \cell +\pard\intbl\qc\fs18 -14.39 (199.519) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -29.00 (-556.0, 518.0) \cell +\pard\intbl\qc\fs18 -5.00 (-394.0, 480.0) \cell +\pard\intbl\qc\fs18 -15.00 (-556.0, 518.0) \cell +\pard\intbl\qc\fs18 -15.00 (-545.0, 469.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -14.45 (-96.50, 67.61) \cell +\pard\intbl\qc\fs18 12.17 (-69.59, 93.94) \cell +\pard\intbl\qc\fs18 -2.84 (-70.77, 65.08) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 347.26 (169.437) \cell +\pard\intbl\qc\fs18 290.20 (168.024) \cell +\pard\intbl\qc\fs18 317.56 (170.259) \cell +\pard\intbl\qc\fs18 264.75 (186.435) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 387.00 (32.0, 595.0) \cell +\pard\intbl\qc\fs18 317.00 (6.0, 592.0) \cell +\pard\intbl\qc\fs18 351.50 (6.0, 595.0) \cell +\pard\intbl\qc\fs18 264.00 (2.0, 555.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 310.34 (172.200) \cell +\pard\intbl\qc\fs18 315.31 (163.341) \cell +\pard\intbl\qc\fs18 312.93 (166.797) \cell +\pard\intbl\qc\fs18 300.39 (175.992) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 36.91 (188.602) \cell +\pard\intbl\qc\fs18 -25.12 (220.597) \cell +\pard\intbl\qc\fs18 4.63 (207.178) \cell +\pard\intbl\qc\fs18 -35.64 (261.006) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 16.00 (-327.0, 515.0) \cell +\pard\intbl\qc\fs18 2.00 (-488.0, 582.0) \cell +\pard\intbl\qc\fs18 11.50 (-488.0, 582.0) \cell +\pard\intbl\qc\fs18 33.00 (-564.0, 542.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 72.55 (-13.27, 158.38) \cell +\pard\intbl\qc\fs18 10.52 (-79.66, 100.71) \cell +\pard\intbl\qc\fs18 40.27 (-37.90, 118.45) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 285.62 (187.555) \cell +\pard\intbl\qc\fs18 280.89 (182.308) \cell +\pard\intbl\qc\fs18 283.12 (183.762) \cell +\pard\intbl\qc\fs18 305.84 (173.822) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 257.00 (19.0, 600.0) \cell +\pard\intbl\qc\fs18 264.00 (11.0, 593.0) \cell +\pard\intbl\qc\fs18 262.00 (11.0, 600.0) \cell +\pard\intbl\qc\fs18 293.00 (14.0, 597.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 301.95 (162.191) \cell +\pard\intbl\qc\fs18 305.04 (164.429) \cell +\pard\intbl\qc\fs18 303.58 (162.455) \cell +\pard\intbl\qc\fs18 301.29 (182.948) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -16.33 (233.981) \cell +\pard\intbl\qc\fs18 -24.15 (229.079) \cell +\pard\intbl\qc\fs18 -20.46 (230.117) \cell +\pard\intbl\qc\fs18 4.55 (242.121) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 6.00 (-457.0, 447.0) \cell +\pard\intbl\qc\fs18 -19.00 (-504.0, 467.0) \cell +\pard\intbl\qc\fs18 -2.00 (-504.0, 467.0) \cell +\pard\intbl\qc\fs18 -20.00 (-509.0, 517.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -20.88 (-117.58, 75.83) \cell +\pard\intbl\qc\fs18 -28.69 (-121.39, 64.00) \cell +\pard\intbl\qc\fs18 -25.01 (-105.77, 55.76) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 299.00 (171.531) \cell +\pard\intbl\qc\fs18 323.00 (173.112) \cell +\pard\intbl\qc\fs18 311.00 (171.626) \cell +\pard\intbl\qc\fs18 321.71 (162.796) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 310.00 (1.0, 591.0) \cell +\pard\intbl\qc\fs18 306.00 (28.0, 600.0) \cell +\pard\intbl\qc\fs18 308.00 (1.0, 600.0) \cell +\pard\intbl\qc\fs18 339.00 (37.0, 594.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 301.26 (157.248) \cell +\pard\intbl\qc\fs18 320.54 (159.133) \cell +\pard\intbl\qc\fs18 310.90 (157.462) \cell +\pard\intbl\qc\fs18 296.88 (186.937) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -2.26 (243.501) \cell +\pard\intbl\qc\fs18 2.46 (231.437) \cell +\pard\intbl\qc\fs18 0.10 (236.010) \cell +\pard\intbl\qc\fs18 24.83 (255.984) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -45.00 (-429.0, 486.0) \cell +\pard\intbl\qc\fs18 26.00 (-443.0, 377.0) \cell +\pard\intbl\qc\fs18 -7.50 (-443.0, 486.0) \cell +\pard\intbl\qc\fs18 -9.50 (-525.0, 505.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -27.08 (-131.94, 77.78) \cell +\pard\intbl\qc\fs18 -22.37 (-124.39, 79.65) \cell +\pard\intbl\qc\fs18 -24.72 (-112.84, 63.40) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 277.56 (174.477) \cell +\pard\intbl\qc\fs18 278.31 (189.874) \cell +\pard\intbl\qc\fs18 277.94 (181.107) \cell +\pard\intbl\qc\fs18 292.73 (173.628) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 273.00 (15.0, 590.0) \cell +\pard\intbl\qc\fs18 260.00 (2.0, 589.0) \cell +\pard\intbl\qc\fs18 267.00 (2.0, 590.0) \cell +\pard\intbl\qc\fs18 308.50 (8.0, 594.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 308.15 (153.691) \cell +\pard\intbl\qc\fs18 320.14 (155.139) \cell +\pard\intbl\qc\fs18 314.23 (153.407) \cell +\pard\intbl\qc\fs18 292.50 (193.368) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -30.59 (206.677) \cell +\pard\intbl\qc\fs18 -41.83 (238.258) \cell +\pard\intbl\qc\fs18 -36.29 (221.687) \cell +\pard\intbl\qc\fs18 0.23 (261.075) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -18.50 (-413.0, 386.0) \cell +\pard\intbl\qc\fs18 -68.00 (-530.0, 381.0) \cell +\pard\intbl\qc\fs18 -32.00 (-530.0, 386.0) \cell +\pard\intbl\qc\fs18 16.50 (-554.0, 468.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -30.82 (-133.79, 72.16) \cell +\pard\intbl\qc\fs18 -42.06 (-151.88, 67.77) \cell +\pard\intbl\qc\fs18 -36.52 (-128.25, 55.21) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 300.46 (127.901) \cell +\pard\intbl\qc\fs18 280.19 (199.099) \cell +\pard\intbl\qc\fs18 290.51 (165.439) \cell +\pard\intbl\qc\fs18 289.67 (180.858) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 317.00 (51.0, 522.0) \cell +\pard\intbl\qc\fs18 266.00 (0.0, 598.0) \cell +\pard\intbl\qc\fs18 305.00 (0.0, 598.0) \cell +\pard\intbl\qc\fs18 276.50 (5.0, 593.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 308.36 (154.789) \cell +\pard\intbl\qc\fs18 342.15 (152.207) \cell +\pard\intbl\qc\fs18 324.95 (153.052) \cell +\pard\intbl\qc\fs18 292.50 (193.368) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -7.89 (201.676) \cell +\pard\intbl\qc\fs18 -61.96 (204.647) \cell +\pard\intbl\qc\fs18 -34.44 (203.090) \cell +\pard\intbl\qc\fs18 -2.83 (259.622) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 7.50 (-427.0, 293.0) \cell +\pard\intbl\qc\fs18 -54.00 (-482.0, 426.0) \cell +\pard\intbl\qc\fs18 -27.00 (-482.0, 426.0) \cell +\pard\intbl\qc\fs18 -45.50 (-441.0, 578.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -5.06 (-111.72, 101.60) \cell +\pard\intbl\qc\fs18 -59.13 (-167.70, 49.44) \cell +\pard\intbl\qc\fs18 -31.60 (-123.83, 60.62) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 256.05 (203.617) \cell +\pard\intbl\qc\fs18 268.77 (129.520) \cell +\pard\intbl\qc\fs18 262.56 (167.845) \cell +\pard\intbl\qc\fs18 292.17 (168.010) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 165.00 (2.0, 576.0) \cell +\pard\intbl\qc\fs18 255.50 (60.0, 569.0) \cell +\pard\intbl\qc\fs18 233.00 (2.0, 576.0) \cell +\pard\intbl\qc\fs18 292.00 (7.0, 596.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 296.10 (144.545) \cell +\pard\intbl\qc\fs18 342.32 (139.246) \cell +\pard\intbl\qc\fs18 319.74 (142.093) \cell +\pard\intbl\qc\fs18 285.96 (190.013) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -40.05 (249.362) \cell +\pard\intbl\qc\fs18 -73.55 (168.315) \cell +\pard\intbl\qc\fs18 -57.19 (209.910) \cell +\pard\intbl\qc\fs18 6.21 (234.560) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -30.00 (-413.0, 512.0) \cell +\pard\intbl\qc\fs18 -73.00 (-357.0, 203.0) \cell +\pard\intbl\qc\fs18 -57.00 (-413.0, 512.0) \cell +\pard\intbl\qc\fs18 2.00 (-416.0, 519.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -46.26 (-176.56, 84.04) \cell +\pard\intbl\qc\fs18 -79.76 (-179.10, 19.58) \cell +\pard\intbl\qc\fs18 -63.40 (-156.51, 29.71) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 292.35 (181.081) \cell +\pard\intbl\qc\fs18 270.05 (172.491) \cell +\pard\intbl\qc\fs18 280.93 (174.870) \cell +\pard\intbl\qc\fs18 316.12 (183.590) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 299.00 (23.0, 595.0) \cell +\pard\intbl\qc\fs18 245.00 (7.0, 597.0) \cell +\pard\intbl\qc\fs18 277.00 (7.0, 597.0) \cell +\pard\intbl\qc\fs18 301.00 (38.0, 591.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 296.50 (148.288) \cell +\pard\intbl\qc\fs18 351.33 (135.947) \cell +\pard\intbl\qc\fs18 324.59 (143.023) \cell +\pard\intbl\qc\fs18 267.17 (191.826) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -4.15 (235.000) \cell +\pard\intbl\qc\fs18 -81.29 (238.629) \cell +\pard\intbl\qc\fs18 -43.66 (237.124) \cell +\pard\intbl\qc\fs18 48.95 (251.963) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 28.00 (-487.0, 360.0) \cell +\pard\intbl\qc\fs18 -92.00 (-458.0, 351.0) \cell +\pard\intbl\qc\fs18 -22.00 (-487.0, 360.0) \cell +\pard\intbl\qc\fs18 75.00 (-522.0, 524.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -53.10 (-185.75, 79.55) \cell +\pard\intbl\qc\fs18 -130.24 (-261.91, 1.44) \cell +\pard\intbl\qc\fs18 -92.61 (-200.15, 14.93) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QT Interval, Corrected (ms) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 366.04 (88.969) \cell +\pard\intbl\qc\fs18 366.84 (94.802) \cell +\pard\intbl\qc\fs18 366.39 (91.138) \cell +\pard\intbl\qc\fs18 369.11 (100.209) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 368.00 (202.0, 525.0) \cell +\pard\intbl\qc\fs18 386.00 (203.0, 508.0) \cell +\pard\intbl\qc\fs18 380.00 (202.0, 525.0) \cell +\pard\intbl\qc\fs18 382.00 (200.0, 521.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 390.35 (89.770) \cell +\pard\intbl\qc\fs18 362.80 (88.424) \cell +\pard\intbl\qc\fs18 378.34 (89.855) \cell +\pard\intbl\qc\fs18 375.05 (96.613) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 390.50 (222.0, 519.0) \cell +\pard\intbl\qc\fs18 376.00 (205.0, 516.0) \cell +\pard\intbl\qc\fs18 381.00 (205.0, 519.0) \cell +\pard\intbl\qc\fs18 370.50 (210.0, 523.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 364.89 (89.147) \cell +\pard\intbl\qc\fs18 366.84 (94.802) \cell +\pard\intbl\qc\fs18 365.74 (91.258) \cell +\pard\intbl\qc\fs18 367.47 (101.366) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 25.45 (128.811) \cell +\pard\intbl\qc\fs18 -4.04 (123.895) \cell +\pard\intbl\qc\fs18 12.60 (127.002) \cell +\pard\intbl\qc\fs18 7.58 (132.729) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 26.00 (-203.0, 259.0) \cell +\pard\intbl\qc\fs18 -7.00 (-257.0, 219.0) \cell +\pard\intbl\qc\fs18 17.00 (-257.0, 259.0) \cell +\pard\intbl\qc\fs18 3.00 (-231.0, 320.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 17.87 (-27.93, 63.67) \cell +\pard\intbl\qc\fs18 -11.62 (-59.56, 36.32) \cell +\pard\intbl\qc\fs18 5.02 (-35.66, 45.69) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 367.70 (95.373) \cell +\pard\intbl\qc\fs18 363.94 (99.092) \cell +\pard\intbl\qc\fs18 365.74 (96.843) \cell +\pard\intbl\qc\fs18 333.62 (90.265) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 372.00 (208.0, 522.0) \cell +\pard\intbl\qc\fs18 368.00 (202.0, 518.0) \cell +\pard\intbl\qc\fs18 371.00 (202.0, 522.0) \cell +\pard\intbl\qc\fs18 306.00 (202.0, 518.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 367.62 (89.551) \cell +\pard\intbl\qc\fs18 366.84 (94.802) \cell +\pard\intbl\qc\fs18 367.21 (91.847) \cell +\pard\intbl\qc\fs18 369.44 (100.997) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.09 (133.940) \cell +\pard\intbl\qc\fs18 -2.90 (131.390) \cell +\pard\intbl\qc\fs18 -1.47 (131.941) \cell +\pard\intbl\qc\fs18 -35.82 (136.640) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 7.00 (-252.0, 272.0) \cell +\pard\intbl\qc\fs18 11.00 (-303.0, 264.0) \cell +\pard\intbl\qc\fs18 9.00 (-303.0, 272.0) \cell +\pard\intbl\qc\fs18 -23.00 (-302.0, 255.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 35.90 (-16.13, 87.93) \cell +\pard\intbl\qc\fs18 32.92 (-17.41, 83.24) \cell +\pard\intbl\qc\fs18 34.35 (-9.18, 77.88) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 359.50 (107.304) \cell +\pard\intbl\qc\fs18 371.02 (108.062) \cell +\pard\intbl\qc\fs18 365.58 (107.248) \cell +\pard\intbl\qc\fs18 344.00 (99.727) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 351.00 (205.0, 514.0) \cell +\pard\intbl\qc\fs18 391.00 (205.0, 524.0) \cell +\pard\intbl\qc\fs18 367.00 (205.0, 524.0) \cell +\pard\intbl\qc\fs18 321.00 (202.0, 525.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 370.74 (89.977) \cell +\pard\intbl\qc\fs18 364.81 (96.025) \cell +\pard\intbl\qc\fs18 367.61 (92.740) \cell +\pard\intbl\qc\fs18 366.27 (101.160) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -11.24 (128.042) \cell +\pard\intbl\qc\fs18 6.21 (146.949) \cell +\pard\intbl\qc\fs18 -2.02 (137.851) \cell +\pard\intbl\qc\fs18 -22.27 (142.224) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -13.00 (-283.0, 256.0) \cell +\pard\intbl\qc\fs18 -14.00 (-275.0, 303.0) \cell +\pard\intbl\qc\fs18 -13.00 (-283.0, 303.0) \cell +\pard\intbl\qc\fs18 -46.00 (-249.0, 288.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 11.03 (-43.65, 65.72) \cell +\pard\intbl\qc\fs18 28.49 (-28.60, 85.57) \cell +\pard\intbl\qc\fs18 20.25 (-27.52, 68.02) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 354.62 (98.746) \cell +\pard\intbl\qc\fs18 370.00 (87.634) \cell +\pard\intbl\qc\fs18 362.31 (93.070) \cell +\pard\intbl\qc\fs18 371.13 (95.494) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 366.00 (211.0, 512.0) \cell +\pard\intbl\qc\fs18 360.00 (205.0, 509.0) \cell +\pard\intbl\qc\fs18 360.50 (205.0, 512.0) \cell +\pard\intbl\qc\fs18 384.00 (207.0, 520.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 363.69 (88.725) \cell +\pard\intbl\qc\fs18 359.59 (95.543) \cell +\pard\intbl\qc\fs18 361.64 (91.620) \cell +\pard\intbl\qc\fs18 370.10 (101.063) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -9.08 (127.607) \cell +\pard\intbl\qc\fs18 10.41 (136.246) \cell +\pard\intbl\qc\fs18 0.67 (131.503) \cell +\pard\intbl\qc\fs18 1.04 (141.795) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -4.00 (-273.0, 217.0) \cell +\pard\intbl\qc\fs18 -19.00 (-241.0, 269.0) \cell +\pard\intbl\qc\fs18 -15.00 (-273.0, 269.0) \cell +\pard\intbl\qc\fs18 0.50 (-297.0, 320.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -10.12 (-66.49, 46.26) \cell +\pard\intbl\qc\fs18 9.37 (-49.04, 67.78) \cell +\pard\intbl\qc\fs18 -0.37 (-49.29, 48.54) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 332.32 (103.683) \cell +\pard\intbl\qc\fs18 389.11 (100.317) \cell +\pard\intbl\qc\fs18 361.13 (105.199) \cell +\pard\intbl\qc\fs18 372.73 (91.839) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 318.00 (203.0, 525.0) \cell +\pard\intbl\qc\fs18 403.00 (203.0, 521.0) \cell +\pard\intbl\qc\fs18 369.00 (203.0, 525.0) \cell +\pard\intbl\qc\fs18 351.50 (205.0, 521.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 364.21 (91.405) \cell +\pard\intbl\qc\fs18 359.66 (98.842) \cell +\pard\intbl\qc\fs18 361.90 (94.577) \cell +\pard\intbl\qc\fs18 371.85 (102.254) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -31.88 (125.751) \cell +\pard\intbl\qc\fs18 29.46 (147.400) \cell +\pard\intbl\qc\fs18 -0.77 (139.613) \cell +\pard\intbl\qc\fs18 0.88 (123.543) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -40.50 (-260.0, 225.0) \cell +\pard\intbl\qc\fs18 22.00 (-247.0, 301.0) \cell +\pard\intbl\qc\fs18 -8.00 (-260.0, 301.0) \cell +\pard\intbl\qc\fs18 -5.50 (-230.0, 241.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -32.76 (-88.56, 23.05) \cell +\pard\intbl\qc\fs18 28.58 (-32.60, 89.77) \cell +\pard\intbl\qc\fs18 -1.64 (-50.21, 46.93) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 391.29 (95.543) \cell +\pard\intbl\qc\fs18 400.63 (79.556) \cell +\pard\intbl\qc\fs18 395.87 (87.372) \cell +\pard\intbl\qc\fs18 385.06 (91.187) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 386.50 (213.0, 523.0) \cell +\pard\intbl\qc\fs18 432.00 (202.0, 490.0) \cell +\pard\intbl\qc\fs18 410.00 (202.0, 523.0) \cell +\pard\intbl\qc\fs18 390.50 (207.0, 524.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 367.29 (92.244) \cell +\pard\intbl\qc\fs18 372.04 (101.473) \cell +\pard\intbl\qc\fs18 369.62 (96.010) \cell +\pard\intbl\qc\fs18 371.85 (102.254) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 24.00 (125.164) \cell +\pard\intbl\qc\fs18 28.59 (135.654) \cell +\pard\intbl\qc\fs18 26.25 (129.223) \cell +\pard\intbl\qc\fs18 13.21 (133.093) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 46.00 (-304.0, 268.0) \cell +\pard\intbl\qc\fs18 39.00 (-251.0, 237.0) \cell +\pard\intbl\qc\fs18 45.00 (-304.0, 268.0) \cell +\pard\intbl\qc\fs18 16.50 (-227.0, 244.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 10.79 (-50.17, 71.76) \cell +\pard\intbl\qc\fs18 15.38 (-49.62, 80.39) \cell +\pard\intbl\qc\fs18 13.05 (-38.42, 64.51) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 368.71 (88.975) \cell +\pard\intbl\qc\fs18 383.14 (104.720) \cell +\pard\intbl\qc\fs18 376.09 (96.468) \cell +\pard\intbl\qc\fs18 375.28 (90.216) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 383.00 (213.0, 510.0) \cell +\pard\intbl\qc\fs18 392.50 (210.0, 522.0) \cell +\pard\intbl\qc\fs18 390.00 (210.0, 522.0) \cell +\pard\intbl\qc\fs18 389.00 (201.0, 511.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 363.33 (90.934) \cell +\pard\intbl\qc\fs18 365.82 (109.398) \cell +\pard\intbl\qc\fs18 364.60 (99.615) \cell +\pard\intbl\qc\fs18 371.06 (103.212) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.38 (129.277) \cell +\pard\intbl\qc\fs18 17.32 (137.064) \cell +\pard\intbl\qc\fs18 11.49 (131.864) \cell +\pard\intbl\qc\fs18 4.21 (119.544) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 5.00 (-201.0, 253.0) \cell +\pard\intbl\qc\fs18 32.00 (-205.0, 315.0) \cell +\pard\intbl\qc\fs18 14.00 (-205.0, 315.0) \cell +\pard\intbl\qc\fs18 -13.00 (-210.0, 228.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 1.17 (-66.10, 68.43) \cell +\pard\intbl\qc\fs18 13.11 (-55.88, 82.09) \cell +\pard\intbl\qc\fs18 7.28 (-45.64, 60.20) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 396.50 (94.440) \cell +\pard\intbl\qc\fs18 340.10 (77.175) \cell +\pard\intbl\qc\fs18 367.61 (89.606) \cell +\pard\intbl\qc\fs18 362.78 (102.397) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 431.00 (232.0, 507.0) \cell +\pard\intbl\qc\fs18 348.00 (244.0, 471.0) \cell +\pard\intbl\qc\fs18 382.00 (232.0, 507.0) \cell +\pard\intbl\qc\fs18 382.00 (201.0, 517.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 364.30 (93.185) \cell +\pard\intbl\qc\fs18 364.90 (112.013) \cell +\pard\intbl\qc\fs18 364.61 (101.972) \cell +\pard\intbl\qc\fs18 372.00 (105.429) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 32.20 (123.460) \cell +\pard\intbl\qc\fs18 -24.81 (147.124) \cell +\pard\intbl\qc\fs18 3.00 (137.460) \cell +\pard\intbl\qc\fs18 -9.22 (143.405) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 47.50 (-216.0, 227.0) \cell +\pard\intbl\qc\fs18 -38.00 (-253.0, 220.0) \cell +\pard\intbl\qc\fs18 -1.00 (-253.0, 227.0) \cell +\pard\intbl\qc\fs18 -39.00 (-275.0, 295.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 41.42 (-30.26, 113.09) \cell +\pard\intbl\qc\fs18 -15.59 (-94.73, 63.55) \cell +\pard\intbl\qc\fs18 12.22 (-49.52, 73.96) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcB Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 345.93 (91.007) \cell +\pard\intbl\qc\fs18 361.27 (107.014) \cell +\pard\intbl\qc\fs18 352.56 (98.104) \cell +\pard\intbl\qc\fs18 363.33 (90.047) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 333.00 (203.0, 516.0) \cell +\pard\intbl\qc\fs18 366.00 (201.0, 524.0) \cell +\pard\intbl\qc\fs18 339.50 (201.0, 524.0) \cell +\pard\intbl\qc\fs18 380.00 (202.0, 518.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 348.89 (93.664) \cell +\pard\intbl\qc\fs18 359.06 (94.491) \cell +\pard\intbl\qc\fs18 353.32 (93.755) \cell +\pard\intbl\qc\fs18 371.29 (102.498) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 358.50 (202.0, 523.0) \cell +\pard\intbl\qc\fs18 378.00 (201.0, 523.0) \cell +\pard\intbl\qc\fs18 368.00 (201.0, 523.0) \cell +\pard\intbl\qc\fs18 376.50 (203.0, 524.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 345.88 (91.703) \cell +\pard\intbl\qc\fs18 361.27 (107.014) \cell +\pard\intbl\qc\fs18 352.59 (98.525) \cell +\pard\intbl\qc\fs18 359.40 (88.678) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 3.02 (130.230) \cell +\pard\intbl\qc\fs18 -2.22 (144.734) \cell +\pard\intbl\qc\fs18 0.74 (136.159) \cell +\pard\intbl\qc\fs18 11.89 (138.879) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -15.00 (-286.0, 277.0) \cell +\pard\intbl\qc\fs18 9.00 (-321.0, 240.0) \cell +\pard\intbl\qc\fs18 -2.00 (-321.0, 277.0) \cell +\pard\intbl\qc\fs18 8.00 (-269.0, 303.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -8.87 (-56.05, 38.30) \cell +\pard\intbl\qc\fs18 -14.10 (-67.37, 39.17) \cell +\pard\intbl\qc\fs18 -11.15 (-54.05, 31.74) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 362.36 (101.513) \cell +\pard\intbl\qc\fs18 377.59 (96.553) \cell +\pard\intbl\qc\fs18 370.29 (98.746) \cell +\pard\intbl\qc\fs18 357.57 (90.355) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 369.00 (204.0, 522.0) \cell +\pard\intbl\qc\fs18 373.00 (203.0, 521.0) \cell +\pard\intbl\qc\fs18 373.00 (203.0, 522.0) \cell +\pard\intbl\qc\fs18 369.00 (201.0, 520.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 346.00 (98.033) \cell +\pard\intbl\qc\fs18 361.27 (107.014) \cell +\pard\intbl\qc\fs18 353.95 (102.564) \cell +\pard\intbl\qc\fs18 361.38 (88.030) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 16.36 (132.343) \cell +\pard\intbl\qc\fs18 16.31 (118.963) \cell +\pard\intbl\qc\fs18 16.34 (124.903) \cell +\pard\intbl\qc\fs18 -3.80 (112.357) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 22.00 (-287.0, 264.0) \cell +\pard\intbl\qc\fs18 6.00 (-222.0, 258.0) \cell +\pard\intbl\qc\fs18 18.50 (-287.0, 264.0) \cell +\pard\intbl\qc\fs18 -28.00 (-223.0, 293.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 20.16 (-27.66, 67.99) \cell +\pard\intbl\qc\fs18 20.12 (-23.53, 63.76) \cell +\pard\intbl\qc\fs18 20.14 (-17.70, 57.98) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 349.12 (93.266) \cell +\pard\intbl\qc\fs18 356.40 (101.713) \cell +\pard\intbl\qc\fs18 352.97 (97.335) \cell +\pard\intbl\qc\fs18 347.02 (90.433) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 364.50 (205.0, 519.0) \cell +\pard\intbl\qc\fs18 352.00 (202.0, 510.0) \cell +\pard\intbl\qc\fs18 358.00 (202.0, 519.0) \cell +\pard\intbl\qc\fs18 329.00 (213.0, 521.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 351.62 (93.401) \cell +\pard\intbl\qc\fs18 361.62 (104.718) \cell +\pard\intbl\qc\fs18 356.90 (99.105) \cell +\pard\intbl\qc\fs18 364.44 (88.440) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -2.50 (136.826) \cell +\pard\intbl\qc\fs18 -5.21 (146.358) \cell +\pard\intbl\qc\fs18 -3.93 (141.143) \cell +\pard\intbl\qc\fs18 -17.42 (127.857) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -26.00 (-277.0, 229.0) \cell +\pard\intbl\qc\fs18 10.00 (-288.0, 271.0) \cell +\pard\intbl\qc\fs18 2.00 (-288.0, 271.0) \cell +\pard\intbl\qc\fs18 -22.00 (-257.0, 304.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 14.92 (-39.28, 69.11) \cell +\pard\intbl\qc\fs18 12.21 (-42.29, 66.70) \cell +\pard\intbl\qc\fs18 13.49 (-31.70, 58.67) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 333.72 (96.850) \cell +\pard\intbl\qc\fs18 362.90 (92.166) \cell +\pard\intbl\qc\fs18 348.31 (95.062) \cell +\pard\intbl\qc\fs18 362.75 (89.853) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 294.00 (206.0, 501.0) \cell +\pard\intbl\qc\fs18 381.00 (200.0, 513.0) \cell +\pard\intbl\qc\fs18 331.50 (200.0, 513.0) \cell +\pard\intbl\qc\fs18 379.50 (200.0, 516.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 353.05 (95.713) \cell +\pard\intbl\qc\fs18 362.85 (100.821) \cell +\pard\intbl\qc\fs18 357.95 (97.784) \cell +\pard\intbl\qc\fs18 362.77 (89.024) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -19.33 (143.779) \cell +\pard\intbl\qc\fs18 0.05 (134.596) \cell +\pard\intbl\qc\fs18 -9.64 (138.699) \cell +\pard\intbl\qc\fs18 -0.02 (119.697) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -25.00 (-295.0, 234.0) \cell +\pard\intbl\qc\fs18 -6.00 (-249.0, 244.0) \cell +\pard\intbl\qc\fs18 -19.50 (-295.0, 244.0) \cell +\pard\intbl\qc\fs18 11.50 (-239.0, 282.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -19.31 (-75.88, 37.25) \cell +\pard\intbl\qc\fs18 0.07 (-54.11, 54.25) \cell +\pard\intbl\qc\fs18 -9.62 (-54.87, 35.62) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 344.76 (90.779) \cell +\pard\intbl\qc\fs18 378.17 (87.638) \cell +\pard\intbl\qc\fs18 361.71 (90.125) \cell +\pard\intbl\qc\fs18 357.48 (91.996) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 335.00 (202.0, 498.0) \cell +\pard\intbl\qc\fs18 391.00 (225.0, 519.0) \cell +\pard\intbl\qc\fs18 369.00 (202.0, 519.0) \cell +\pard\intbl\qc\fs18 359.50 (214.0, 510.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 350.94 (97.531) \cell +\pard\intbl\qc\fs18 354.71 (101.112) \cell +\pard\intbl\qc\fs18 352.86 (98.649) \cell +\pard\intbl\qc\fs18 364.44 (86.200) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -6.18 (135.985) \cell +\pard\intbl\qc\fs18 23.46 (147.155) \cell +\pard\intbl\qc\fs18 8.86 (141.506) \cell +\pard\intbl\qc\fs18 -6.96 (133.743) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 3.50 (-297.0, 204.0) \cell +\pard\intbl\qc\fs18 30.00 (-281.0, 253.0) \cell +\pard\intbl\qc\fs18 18.00 (-297.0, 253.0) \cell +\pard\intbl\qc\fs18 2.00 (-243.0, 269.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 0.78 (-59.59, 61.15) \cell +\pard\intbl\qc\fs18 30.42 (-32.39, 93.23) \cell +\pard\intbl\qc\fs18 15.81 (-35.24, 66.86) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 380.75 (90.147) \cell +\pard\intbl\qc\fs18 384.07 (95.848) \cell +\pard\intbl\qc\fs18 382.38 (92.138) \cell +\pard\intbl\qc\fs18 372.31 (92.144) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 388.50 (219.0, 522.0) \cell +\pard\intbl\qc\fs18 391.00 (211.0, 525.0) \cell +\pard\intbl\qc\fs18 390.00 (211.0, 525.0) \cell +\pard\intbl\qc\fs18 363.00 (205.0, 503.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 357.75 (102.374) \cell +\pard\intbl\qc\fs18 346.22 (104.532) \cell +\pard\intbl\qc\fs18 352.09 (102.641) \cell +\pard\intbl\qc\fs18 364.44 (86.200) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 23.00 (149.843) \cell +\pard\intbl\qc\fs18 37.85 (141.951) \cell +\pard\intbl\qc\fs18 30.29 (144.860) \cell +\pard\intbl\qc\fs18 7.88 (132.849) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 57.00 (-236.0, 227.0) \cell +\pard\intbl\qc\fs18 73.00 (-239.0, 283.0) \cell +\pard\intbl\qc\fs18 62.00 (-239.0, 283.0) \cell +\pard\intbl\qc\fs18 15.50 (-257.0, 280.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 15.13 (-53.52, 83.77) \cell +\pard\intbl\qc\fs18 29.98 (-37.03, 96.98) \cell +\pard\intbl\qc\fs18 22.42 (-31.88, 76.72) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 381.00 (103.266) \cell +\pard\intbl\qc\fs18 368.27 (90.621) \cell +\pard\intbl\qc\fs18 374.49 (96.050) \cell +\pard\intbl\qc\fs18 349.40 (103.255) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 386.00 (215.0, 521.0) \cell +\pard\intbl\qc\fs18 355.50 (216.0, 520.0) \cell +\pard\intbl\qc\fs18 374.00 (215.0, 521.0) \cell +\pard\intbl\qc\fs18 360.00 (200.0, 523.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 363.90 (102.208) \cell +\pard\intbl\qc\fs18 352.77 (102.844) \cell +\pard\intbl\qc\fs18 358.21 (101.463) \cell +\pard\intbl\qc\fs18 365.15 (86.989) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 17.10 (142.540) \cell +\pard\intbl\qc\fs18 15.50 (108.210) \cell +\pard\intbl\qc\fs18 16.28 (124.621) \cell +\pard\intbl\qc\fs18 -15.74 (143.463) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 4.00 (-250.0, 278.0) \cell +\pard\intbl\qc\fs18 26.00 (-240.0, 169.0) \cell +\pard\intbl\qc\fs18 15.00 (-250.0, 278.0) \cell +\pard\intbl\qc\fs18 -10.00 (-301.0, 260.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 32.84 (-43.00, 108.68) \cell +\pard\intbl\qc\fs18 31.24 (-31.22, 93.71) \cell +\pard\intbl\qc\fs18 32.02 (-24.15, 88.20) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 378.00 (97.829) \cell +\pard\intbl\qc\fs18 349.52 (85.391) \cell +\pard\intbl\qc\fs18 363.41 (91.649) \cell +\pard\intbl\qc\fs18 362.34 (97.318) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 391.50 (229.0, 503.0) \cell +\pard\intbl\qc\fs18 346.00 (232.0, 509.0) \cell +\pard\intbl\qc\fs18 356.00 (229.0, 509.0) \cell +\pard\intbl\qc\fs18 370.00 (208.0, 520.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 371.95 (97.803) \cell +\pard\intbl\qc\fs18 346.57 (101.081) \cell +\pard\intbl\qc\fs18 358.95 (99.082) \cell +\pard\intbl\qc\fs18 373.44 (82.679) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 6.05 (159.031) \cell +\pard\intbl\qc\fs18 2.95 (136.074) \cell +\pard\intbl\qc\fs18 4.46 (145.855) \cell +\pard\intbl\qc\fs18 -11.10 (126.105) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -21.00 (-287.0, 233.0) \cell +\pard\intbl\qc\fs18 19.00 (-250.0, 219.0) \cell +\pard\intbl\qc\fs18 16.00 (-287.0, 233.0) \cell +\pard\intbl\qc\fs18 -28.00 (-271.0, 306.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 17.15 (-65.75, 100.05) \cell +\pard\intbl\qc\fs18 14.05 (-58.09, 86.19) \cell +\pard\intbl\qc\fs18 15.56 (-44.38, 75.51) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcF Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 368.67 (97.490) \cell +\pard\intbl\qc\fs18 342.76 (88.400) \cell +\pard\intbl\qc\fs18 357.47 (94.165) \cell +\pard\intbl\qc\fs18 386.08 (96.830) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 378.00 (200.0, 518.0) \cell +\pard\intbl\qc\fs18 339.00 (202.0, 520.0) \cell +\pard\intbl\qc\fs18 361.00 (200.0, 520.0) \cell +\pard\intbl\qc\fs18 410.00 (201.0, 522.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 343.12 (89.259) \cell +\pard\intbl\qc\fs18 335.06 (100.548) \cell +\pard\intbl\qc\fs18 339.61 (94.011) \cell +\pard\intbl\qc\fs18 359.82 (91.410) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 345.50 (201.0, 516.0) \cell +\pard\intbl\qc\fs18 338.00 (206.0, 507.0) \cell +\pard\intbl\qc\fs18 344.00 (201.0, 516.0) \cell +\pard\intbl\qc\fs18 360.50 (214.0, 523.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 367.80 (97.975) \cell +\pard\intbl\qc\fs18 342.76 (88.400) \cell +\pard\intbl\qc\fs18 356.89 (94.354) \cell +\pard\intbl\qc\fs18 386.85 (94.373) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -24.68 (131.906) \cell +\pard\intbl\qc\fs18 -7.71 (119.548) \cell +\pard\intbl\qc\fs18 -17.28 (126.417) \cell +\pard\intbl\qc\fs18 -27.03 (109.555) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -35.50 (-264.0, 304.0) \cell +\pard\intbl\qc\fs18 -2.00 (-244.0, 246.0) \cell +\pard\intbl\qc\fs18 -23.00 (-264.0, 304.0) \cell +\pard\intbl\qc\fs18 -36.00 (-235.0, 246.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 2.35 (-39.97, 44.67) \cell +\pard\intbl\qc\fs18 19.33 (-23.85, 62.50) \cell +\pard\intbl\qc\fs18 9.75 (-26.17, 45.67) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 359.83 (90.511) \cell +\pard\intbl\qc\fs18 355.94 (85.107) \cell +\pard\intbl\qc\fs18 357.81 (87.306) \cell +\pard\intbl\qc\fs18 362.57 (90.582) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 368.00 (202.0, 503.0) \cell +\pard\intbl\qc\fs18 342.00 (204.0, 525.0) \cell +\pard\intbl\qc\fs18 358.50 (202.0, 525.0) \cell +\pard\intbl\qc\fs18 366.00 (203.0, 520.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 355.06 (101.023) \cell +\pard\intbl\qc\fs18 342.76 (88.400) \cell +\pard\intbl\qc\fs18 348.66 (94.372) \cell +\pard\intbl\qc\fs18 385.64 (94.666) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 4.77 (116.463) \cell +\pard\intbl\qc\fs18 13.18 (130.070) \cell +\pard\intbl\qc\fs18 9.14 (123.170) \cell +\pard\intbl\qc\fs18 -23.07 (133.393) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -2.00 (-255.0, 248.0) \cell +\pard\intbl\qc\fs18 14.00 (-293.0, 292.0) \cell +\pard\intbl\qc\fs18 4.00 (-293.0, 292.0) \cell +\pard\intbl\qc\fs18 -17.00 (-303.0, 270.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 27.83 (-19.94, 75.60) \cell +\pard\intbl\qc\fs18 36.24 (-13.25, 85.74) \cell +\pard\intbl\qc\fs18 32.21 (-9.63, 74.05) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 350.05 (99.027) \cell +\pard\intbl\qc\fs18 317.32 (95.066) \cell +\pard\intbl\qc\fs18 332.76 (97.790) \cell +\pard\intbl\qc\fs18 364.22 (106.229) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 338.50 (203.0, 520.0) \cell +\pard\intbl\qc\fs18 300.00 (201.0, 525.0) \cell +\pard\intbl\qc\fs18 314.00 (201.0, 525.0) \cell +\pard\intbl\qc\fs18 357.00 (201.0, 516.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 362.71 (97.460) \cell +\pard\intbl\qc\fs18 344.40 (91.053) \cell +\pard\intbl\qc\fs18 353.04 (94.041) \cell +\pard\intbl\qc\fs18 384.58 (92.750) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -12.67 (157.542) \cell +\pard\intbl\qc\fs18 -27.09 (136.283) \cell +\pard\intbl\qc\fs18 -20.28 (146.030) \cell +\pard\intbl\qc\fs18 -20.36 (127.783) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -19.50 (-315.0, 317.0) \cell +\pard\intbl\qc\fs18 -22.00 (-290.0, 287.0) \cell +\pard\intbl\qc\fs18 -20.00 (-315.0, 317.0) \cell +\pard\intbl\qc\fs18 -30.00 (-270.0, 266.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 7.70 (-51.63, 67.02) \cell +\pard\intbl\qc\fs18 -6.72 (-58.95, 45.50) \cell +\pard\intbl\qc\fs18 0.08 (-45.75, 45.92) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 365.31 (85.027) \cell +\pard\intbl\qc\fs18 364.90 (102.731) \cell +\pard\intbl\qc\fs18 365.10 (93.681) \cell +\pard\intbl\qc\fs18 359.37 (99.788) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 364.00 (205.0, 522.0) \cell +\pard\intbl\qc\fs18 357.00 (212.0, 525.0) \cell +\pard\intbl\qc\fs18 362.00 (205.0, 525.0) \cell +\pard\intbl\qc\fs18 344.50 (208.0, 522.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 359.44 (98.292) \cell +\pard\intbl\qc\fs18 339.23 (86.566) \cell +\pard\intbl\qc\fs18 349.33 (92.572) \cell +\pard\intbl\qc\fs18 378.79 (91.676) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.87 (131.879) \cell +\pard\intbl\qc\fs18 25.67 (152.523) \cell +\pard\intbl\qc\fs18 15.77 (141.996) \cell +\pard\intbl\qc\fs18 -19.42 (146.051) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.00 (-224.0, 277.0) \cell +\pard\intbl\qc\fs18 20.00 (-278.0, 300.0) \cell +\pard\intbl\qc\fs18 3.00 (-278.0, 300.0) \cell +\pard\intbl\qc\fs18 -32.50 (-305.0, 312.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 25.29 (-32.87, 83.46) \cell +\pard\intbl\qc\fs18 45.09 (-18.05, 108.23) \cell +\pard\intbl\qc\fs18 35.19 (-16.07, 86.45) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 384.12 (93.736) \cell +\pard\intbl\qc\fs18 368.46 (83.830) \cell +\pard\intbl\qc\fs18 376.17 (88.543) \cell +\pard\intbl\qc\fs18 366.56 (94.646) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 389.50 (209.0, 525.0) \cell +\pard\intbl\qc\fs18 361.00 (213.0, 503.0) \cell +\pard\intbl\qc\fs18 385.00 (209.0, 525.0) \cell +\pard\intbl\qc\fs18 372.50 (201.0, 497.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 359.56 (99.325) \cell +\pard\intbl\qc\fs18 341.91 (85.946) \cell +\pard\intbl\qc\fs18 350.61 (92.520) \cell +\pard\intbl\qc\fs18 382.56 (87.490) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 24.56 (144.487) \cell +\pard\intbl\qc\fs18 26.54 (124.878) \cell +\pard\intbl\qc\fs18 25.57 (133.901) \cell +\pard\intbl\qc\fs18 -16.00 (133.594) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 24.00 (-294.0, 308.0) \cell +\pard\intbl\qc\fs18 54.00 (-262.0, 222.0) \cell +\pard\intbl\qc\fs18 32.00 (-294.0, 308.0) \cell +\pard\intbl\qc\fs18 -0.50 (-294.0, 267.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 40.56 (-22.10, 103.22) \cell +\pard\intbl\qc\fs18 42.54 (-14.40, 99.48) \cell +\pard\intbl\qc\fs18 41.57 (-8.29, 91.42) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 347.64 (106.161) \cell +\pard\intbl\qc\fs18 357.81 (112.696) \cell +\pard\intbl\qc\fs18 352.64 (108.519) \cell +\pard\intbl\qc\fs18 347.06 (91.510) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 349.00 (202.0, 511.0) \cell +\pard\intbl\qc\fs18 352.00 (208.0, 523.0) \cell +\pard\intbl\qc\fs18 352.00 (202.0, 523.0) \cell +\pard\intbl\qc\fs18 356.00 (201.0, 518.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 356.86 (94.672) \cell +\pard\intbl\qc\fs18 338.41 (81.183) \cell +\pard\intbl\qc\fs18 347.80 (87.985) \cell +\pard\intbl\qc\fs18 382.56 (87.490) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -9.21 (140.473) \cell +\pard\intbl\qc\fs18 19.41 (146.707) \cell +\pard\intbl\qc\fs18 4.84 (142.960) \cell +\pard\intbl\qc\fs18 -35.50 (124.819) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -11.00 (-279.0, 226.0) \cell +\pard\intbl\qc\fs18 4.00 (-268.0, 288.0) \cell +\pard\intbl\qc\fs18 -4.00 (-279.0, 288.0) \cell +\pard\intbl\qc\fs18 -34.00 (-301.0, 218.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 26.29 (-38.11, 90.68) \cell +\pard\intbl\qc\fs18 54.91 (-12.46, 122.28) \cell +\pard\intbl\qc\fs18 40.34 (-12.00, 92.68) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 347.10 (93.963) \cell +\pard\intbl\qc\fs18 333.27 (91.514) \cell +\pard\intbl\qc\fs18 340.02 (91.873) \cell +\pard\intbl\qc\fs18 381.74 (97.460) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 345.00 (203.0, 494.0) \cell +\pard\intbl\qc\fs18 303.00 (211.0, 523.0) \cell +\pard\intbl\qc\fs18 343.00 (203.0, 523.0) \cell +\pard\intbl\qc\fs18 422.00 (203.0, 524.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 380.81 (91.078) \cell +\pard\intbl\qc\fs18 350.64 (71.525) \cell +\pard\intbl\qc\fs18 365.37 (82.103) \cell +\pard\intbl\qc\fs18 386.34 (84.385) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -33.71 (144.720) \cell +\pard\intbl\qc\fs18 -17.36 (113.941) \cell +\pard\intbl\qc\fs18 -25.35 (128.581) \cell +\pard\intbl\qc\fs18 -4.60 (104.040) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -54.00 (-232.0, 264.0) \cell +\pard\intbl\qc\fs18 -14.00 (-265.0, 219.0) \cell +\pard\intbl\qc\fs18 -31.00 (-265.0, 264.0) \cell +\pard\intbl\qc\fs18 13.00 (-257.0, 186.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -29.12 (-100.71, 42.48) \cell +\pard\intbl\qc\fs18 -12.77 (-70.76, 45.22) \cell +\pard\intbl\qc\fs18 -20.75 (-70.09, 28.58) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 350.95 (94.968) \cell +\pard\intbl\qc\fs18 383.62 (103.330) \cell +\pard\intbl\qc\fs18 367.68 (99.478) \cell +\pard\intbl\qc\fs18 348.37 (94.563) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 360.50 (209.0, 523.0) \cell +\pard\intbl\qc\fs18 403.00 (215.0, 520.0) \cell +\pard\intbl\qc\fs18 398.00 (209.0, 523.0) \cell +\pard\intbl\qc\fs18 359.00 (202.0, 516.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 380.25 (93.407) \cell +\pard\intbl\qc\fs18 344.38 (66.840) \cell +\pard\intbl\qc\fs18 361.88 (81.900) \cell +\pard\intbl\qc\fs18 381.29 (81.927) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -29.30 (122.606) \cell +\pard\intbl\qc\fs18 39.24 (122.980) \cell +\pard\intbl\qc\fs18 5.80 (126.116) \cell +\pard\intbl\qc\fs18 -32.93 (118.044) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -18.50 (-245.0, 275.0) \cell +\pard\intbl\qc\fs18 41.00 (-199.0, 214.0) \cell +\pard\intbl\qc\fs18 9.00 (-245.0, 275.0) \cell +\pard\intbl\qc\fs18 -42.00 (-271.0, 215.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 3.63 (-63.34, 70.60) \cell +\pard\intbl\qc\fs18 72.16 (6.31, 138.02) \cell +\pard\intbl\qc\fs18 38.73 (-14.96, 92.42) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 313.99 (173.985) \cell +\pard\intbl\qc\fs18 312.37 (183.417) \cell +\pard\intbl\qc\fs18 313.29 (177.350) \cell +\pard\intbl\qc\fs18 304.36 (173.630) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 336.00 (18.0, 596.0) \cell +\pard\intbl\qc\fs18 347.00 (20.0, 594.0) \cell +\pard\intbl\qc\fs18 338.00 (18.0, 596.0) \cell +\pard\intbl\qc\fs18 323.50 (5.0, 596.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 296.58 (175.999) \cell +\pard\intbl\qc\fs18 316.16 (171.345) \cell +\pard\intbl\qc\fs18 305.11 (173.513) \cell +\pard\intbl\qc\fs18 272.06 (160.924) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 307.50 (1.0, 599.0) \cell +\pard\intbl\qc\fs18 333.00 (9.0, 581.0) \cell +\pard\intbl\qc\fs18 327.00 (1.0, 599.0) \cell +\pard\intbl\qc\fs18 258.00 (5.0, 582.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 318.26 (171.740) \cell +\pard\intbl\qc\fs18 312.37 (183.417) \cell +\pard\intbl\qc\fs18 315.69 (176.172) \cell +\pard\intbl\qc\fs18 303.77 (170.199) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -21.68 (259.433) \cell +\pard\intbl\qc\fs18 3.78 (268.573) \cell +\pard\intbl\qc\fs18 -10.58 (262.614) \cell +\pard\intbl\qc\fs18 -31.71 (233.634) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -28.50 (-528.0, 475.0) \cell +\pard\intbl\qc\fs18 34.00 (-564.0, 501.0) \cell +\pard\intbl\qc\fs18 18.00 (-564.0, 501.0) \cell +\pard\intbl\qc\fs18 -38.00 (-467.0, 517.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 10.03 (-76.24, 96.29) \cell +\pard\intbl\qc\fs18 35.49 (-59.55, 130.53) \cell +\pard\intbl\qc\fs18 21.13 (-54.68, 96.94) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 306.60 (153.486) \cell +\pard\intbl\qc\fs18 293.76 (185.543) \cell +\pard\intbl\qc\fs18 299.92 (170.173) \cell +\pard\intbl\qc\fs18 262.61 (161.134) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 304.00 (23.0, 599.0) \cell +\pard\intbl\qc\fs18 313.00 (5.0, 599.0) \cell +\pard\intbl\qc\fs18 309.50 (5.0, 599.0) \cell +\pard\intbl\qc\fs18 234.00 (23.0, 595.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 312.36 (176.710) \cell +\pard\intbl\qc\fs18 312.37 (183.417) \cell +\pard\intbl\qc\fs18 312.37 (179.303) \cell +\pard\intbl\qc\fs18 300.54 (169.681) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -5.77 (228.625) \cell +\pard\intbl\qc\fs18 -18.61 (237.419) \cell +\pard\intbl\qc\fs18 -12.45 (232.131) \cell +\pard\intbl\qc\fs18 -37.93 (218.302) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 21.00 (-502.0, 452.0) \cell +\pard\intbl\qc\fs18 4.00 (-495.0, 571.0) \cell +\pard\intbl\qc\fs18 21.00 (-502.0, 571.0) \cell +\pard\intbl\qc\fs18 -51.00 (-485.0, 430.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 32.17 (-54.20, 118.53) \cell +\pard\intbl\qc\fs18 19.33 (-66.82, 105.47) \cell +\pard\intbl\qc\fs18 25.49 (-46.68, 97.65) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 299.79 (193.670) \cell +\pard\intbl\qc\fs18 309.68 (182.210) \cell +\pard\intbl\qc\fs18 305.01 (186.694) \cell +\pard\intbl\qc\fs18 291.76 (171.291) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 335.00 (3.0, 587.0) \cell +\pard\intbl\qc\fs18 293.00 (28.0, 587.0) \cell +\pard\intbl\qc\fs18 310.00 (3.0, 587.0) \cell +\pard\intbl\qc\fs18 315.00 (12.0, 579.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 306.93 (179.129) \cell +\pard\intbl\qc\fs18 310.38 (185.842) \cell +\pard\intbl\qc\fs18 308.75 (181.676) \cell +\pard\intbl\qc\fs18 295.33 (175.833) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -7.14 (203.114) \cell +\pard\intbl\qc\fs18 -0.70 (252.798) \cell +\pard\intbl\qc\fs18 -3.74 (229.429) \cell +\pard\intbl\qc\fs18 -3.56 (226.624) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -16.50 (-417.0, 533.0) \cell +\pard\intbl\qc\fs18 -25.00 (-509.0, 528.0) \cell +\pard\intbl\qc\fs18 -20.00 (-509.0, 533.0) \cell +\pard\intbl\qc\fs18 -29.00 (-412.0, 512.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -3.58 (-90.51, 83.35) \cell +\pard\intbl\qc\fs18 2.86 (-92.23, 97.96) \cell +\pard\intbl\qc\fs18 -0.18 (-77.53, 77.18) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 309.82 (194.252) \cell +\pard\intbl\qc\fs18 281.97 (185.367) \cell +\pard\intbl\qc\fs18 295.90 (189.144) \cell +\pard\intbl\qc\fs18 275.58 (157.384) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 295.00 (15.0, 591.0) \cell +\pard\intbl\qc\fs18 250.00 (1.0, 589.0) \cell +\pard\intbl\qc\fs18 271.00 (1.0, 591.0) \cell +\pard\intbl\qc\fs18 289.00 (0.0, 575.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 304.33 (184.982) \cell +\pard\intbl\qc\fs18 318.92 (183.220) \cell +\pard\intbl\qc\fs18 311.63 (183.051) \cell +\pard\intbl\qc\fs18 294.98 (176.692) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.49 (261.351) \cell +\pard\intbl\qc\fs18 -36.95 (233.391) \cell +\pard\intbl\qc\fs18 -15.73 (247.076) \cell +\pard\intbl\qc\fs18 -19.40 (252.140) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -3.00 (-500.0, 459.0) \cell +\pard\intbl\qc\fs18 28.00 (-518.0, 376.0) \cell +\pard\intbl\qc\fs18 23.00 (-518.0, 459.0) \cell +\pard\intbl\qc\fs18 -1.00 (-474.0, 447.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 24.89 (-83.63, 133.41) \cell +\pard\intbl\qc\fs18 -17.54 (-119.30, 84.21) \cell +\pard\intbl\qc\fs18 3.67 (-85.09, 92.44) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 309.50 (147.727) \cell +\pard\intbl\qc\fs18 236.57 (158.821) \cell +\pard\intbl\qc\fs18 272.51 (156.690) \cell +\pard\intbl\qc\fs18 272.54 (188.882) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 320.50 (47.0, 579.0) \cell +\pard\intbl\qc\fs18 255.00 (2.0, 504.0) \cell +\pard\intbl\qc\fs18 258.00 (2.0, 579.0) \cell +\pard\intbl\qc\fs18 286.00 (3.0, 600.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 303.24 (187.318) \cell +\pard\intbl\qc\fs18 305.69 (184.580) \cell +\pard\intbl\qc\fs18 304.48 (184.566) \cell +\pard\intbl\qc\fs18 291.44 (177.755) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 6.26 (219.614) \cell +\pard\intbl\qc\fs18 -69.11 (247.328) \cell +\pard\intbl\qc\fs18 -31.97 (235.441) \cell +\pard\intbl\qc\fs18 -18.90 (264.593) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -4.00 (-480.0, 344.0) \cell +\pard\intbl\qc\fs18 -87.00 (-522.0, 358.0) \cell +\pard\intbl\qc\fs18 -21.00 (-522.0, 358.0) \cell +\pard\intbl\qc\fs18 -48.50 (-497.0, 590.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 25.16 (-81.63, 131.95) \cell +\pard\intbl\qc\fs18 -50.22 (-162.99, 62.56) \cell +\pard\intbl\qc\fs18 -13.08 (-107.51, 81.36) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 293.36 (171.603) \cell +\pard\intbl\qc\fs18 319.63 (173.776) \cell +\pard\intbl\qc\fs18 306.25 (171.579) \cell +\pard\intbl\qc\fs18 312.88 (183.306) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 283.50 (3.0, 584.0) \cell +\pard\intbl\qc\fs18 343.00 (10.0, 591.0) \cell +\pard\intbl\qc\fs18 299.00 (3.0, 591.0) \cell +\pard\intbl\qc\fs18 307.00 (20.0, 596.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 297.07 (182.967) \cell +\pard\intbl\qc\fs18 293.93 (176.420) \cell +\pard\intbl\qc\fs18 295.53 (178.120) \cell +\pard\intbl\qc\fs18 291.44 (177.755) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -3.71 (257.138) \cell +\pard\intbl\qc\fs18 25.70 (246.945) \cell +\pard\intbl\qc\fs18 10.73 (250.284) \cell +\pard\intbl\qc\fs18 21.44 (229.260) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -58.00 (-456.0, 459.0) \cell +\pard\intbl\qc\fs18 60.00 (-433.0, 500.0) \cell +\pard\intbl\qc\fs18 22.00 (-456.0, 500.0) \cell +\pard\intbl\qc\fs18 9.50 (-455.0, 460.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -25.15 (-143.15, 92.85) \cell +\pard\intbl\qc\fs18 4.27 (-112.01, 120.54) \cell +\pard\intbl\qc\fs18 -10.71 (-104.47, 83.05) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 300.90 (151.992) \cell +\pard\intbl\qc\fs18 304.23 (196.411) \cell +\pard\intbl\qc\fs18 302.60 (174.046) \cell +\pard\intbl\qc\fs18 340.72 (159.160) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 306.00 (42.0, 596.0) \cell +\pard\intbl\qc\fs18 345.00 (15.0, 577.0) \cell +\pard\intbl\qc\fs18 314.00 (15.0, 596.0) \cell +\pard\intbl\qc\fs18 381.00 (15.0, 580.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 290.62 (174.710) \cell +\pard\intbl\qc\fs18 300.77 (180.303) \cell +\pard\intbl\qc\fs18 295.81 (175.545) \cell +\pard\intbl\qc\fs18 288.55 (178.538) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 10.29 (240.814) \cell +\pard\intbl\qc\fs18 3.45 (270.963) \cell +\pard\intbl\qc\fs18 6.79 (253.648) \cell +\pard\intbl\qc\fs18 52.17 (258.420) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 17.00 (-376.0, 454.0) \cell +\pard\intbl\qc\fs18 46.00 (-516.0, 496.0) \cell +\pard\intbl\qc\fs18 40.00 (-516.0, 496.0) \cell +\pard\intbl\qc\fs18 53.00 (-432.0, 489.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 -41.88 (-172.48, 88.71) \cell +\pard\intbl\qc\fs18 -48.72 (-188.19, 90.76) \cell +\pard\intbl\qc\fs18 -45.38 (-152.72, 61.96) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 348.00 (184.570) \cell +\pard\intbl\qc\fs18 312.00 (203.680) \cell +\pard\intbl\qc\fs18 329.56 (193.018) \cell +\pard\intbl\qc\fs18 271.20 (184.577) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 405.50 (4.0, 558.0) \cell +\pard\intbl\qc\fs18 360.00 (0.0, 596.0) \cell +\pard\intbl\qc\fs18 394.00 (0.0, 596.0) \cell +\pard\intbl\qc\fs18 256.00 (4.0, 583.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 281.25 (173.752) \cell +\pard\intbl\qc\fs18 313.76 (173.889) \cell +\pard\intbl\qc\fs18 297.90 (172.422) \cell +\pard\intbl\qc\fs18 277.73 (175.665) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 66.75 (290.518) \cell +\pard\intbl\qc\fs18 -1.76 (314.613) \cell +\pard\intbl\qc\fs18 31.66 (301.302) \cell +\pard\intbl\qc\fs18 -6.54 (279.539) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 194.00 (-394.0, 431.0) \cell +\pard\intbl\qc\fs18 80.00 (-529.0, 551.0) \cell +\pard\intbl\qc\fs18 139.00 (-529.0, 551.0) \cell +\pard\intbl\qc\fs18 -15.00 (-477.0, 531.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2837 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5303 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7954 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10297 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean [vs. placebo] (95% CI) \cell +\pard\intbl\qc\fs18 73.29 (-85.37, 231.95) \cell +\pard\intbl\qc\fs18 4.77 (-160.16, 169.71) \cell +\pard\intbl\qc\fs18 38.20 (-89.55, 165.94) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2837 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5303 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7954 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10297 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5303 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7954 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10297 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfecg01apart2/tsfecg01apart2of3.rtf b/tests/testthat/_snaps/tsfecg01a/tsfecg01apart1of3.rtf similarity index 53% rename from tests/testthat/_snaps/tsfecg01apart2/tsfecg01apart2of3.rtf rename to tests/testthat/_snaps/tsfecg01a/tsfecg01apart1of3.rtf index a4fb0cfc..c5112c2a 100644 --- a/tests/testthat/_snaps/tsfecg01apart2/tsfecg01apart2of3.rtf +++ b/tests/testthat/_snaps/tsfecg01a/tsfecg01apart1of3.rtf @@ -3,10 +3,10 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2802 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5510 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8872 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG01apart2of3:\tab Dummy Title\b0 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2833 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5483 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8955 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG01apart1of3:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -15,9 +15,9 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2802 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5510 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8872 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2833 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5483 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8955 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -27,9 +27,9 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell @@ -39,21 +39,21 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5510 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5483 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8955 \clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2802 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5510 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2833 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5483 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8955 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell \pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell \pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell @@ -63,11 +63,11 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -75,9 +75,9 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -87,9 +87,9 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -99,45 +99,45 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 345.6 (90.1, 601.1) \cell +\pard\intbl\qc\fs18 4/4 (100.0%) \cell +\pard\intbl\qc\fs18 443.0 (251.2, 634.8) \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 323.0 (131.7, 514.3) \cell -\pard\intbl\qc\fs18 -22.6 (-339.7, 294.5) \cell +\pard\intbl\qc\fs18 4/4 (100.0%) \cell +\pard\intbl\qc\fs18 269.2 (-29.3, 567.8) \cell +\pard\intbl\qc\fs18 -173.8 (-589.7, 242.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 197.6 (-87.5, 482.7) \cell -\pard\intbl\qc\fs18 -148.0 (-413.0, 117.0) \cell +\pard\intbl\qc\fs18 4/4 (100.0%) \cell +\pard\intbl\qc\fs18 299.2 (-166.4, 764.9) \cell +\pard\intbl\qc\fs18 -143.8 (-532.1, 244.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -147,10 +147,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (ms) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -159,45 +159,45 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 302.8 (68.8, 536.8) \cell +\pard\intbl\qc\fs18 4/4 (100.0%) \cell +\pard\intbl\qc\fs18 239.2 (-140.0, 618.5) \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 256.0 (83.3, 428.7) \cell -\pard\intbl\qc\fs18 -46.8 (-404.7, 311.1) \cell +\pard\intbl\qc\fs18 4/4 (100.0%) \cell +\pard\intbl\qc\fs18 309.5 (156.1, 462.9) \cell +\pard\intbl\qc\fs18 70.2 (-429.6, 570.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 307.4 (70.3, 544.5) \cell -\pard\intbl\qc\fs18 4.6 (-457.1, 466.3) \cell +\pard\intbl\qc\fs18 4/4 (100.0%) \cell +\pard\intbl\qc\fs18 343.2 (22.2, 664.3) \cell +\pard\intbl\qc\fs18 104.0 (-566.1, 774.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -207,11 +207,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -219,9 +219,9 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -231,9 +231,9 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -243,45 +243,45 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 367.2 (270.8, 463.7) \cell +\pard\intbl\qc\fs18 19/19 (100.0%) \cell +\pard\intbl\qc\fs18 316.2 (219.1, 413.4) \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 383.9 (294.6, 473.3) \cell -\pard\intbl\qc\fs18 16.7 (-126.1, 159.6) \cell +\pard\intbl\qc\fs18 19/19 (100.0%) \cell +\pard\intbl\qc\fs18 394.9 (320.5, 469.3) \cell +\pard\intbl\qc\fs18 78.7 (-44.3, 201.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 10/10 (100.0%) \cell -\pard\intbl\qc\fs18 259.2 (123.8, 394.6) \cell -\pard\intbl\qc\fs18 -119.8 (-326.3, 86.7) \cell +\pard\intbl\qc\fs18 12/12 (100.0%) \cell +\pard\intbl\qc\fs18 278.8 (175.6, 382.1) \cell +\pard\intbl\qc\fs18 -34.2 (-212.7, 144.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -291,10 +291,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (ms) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -303,45 +303,45 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 362.1 (295.1, 429.0) \cell +\pard\intbl\qc\fs18 19/19 (100.0%) \cell +\pard\intbl\qc\fs18 331.1 (267.5, 394.6) \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 249.1 (146.1, 352.0) \cell -\pard\intbl\qc\fs18 -113.0 (-240.4, 14.4) \cell +\pard\intbl\qc\fs18 19/19 (100.0%) \cell +\pard\intbl\qc\fs18 275.6 (192.4, 358.7) \cell +\pard\intbl\qc\fs18 -55.5 (-166.7, 55.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 10/10 (100.0%) \cell -\pard\intbl\qc\fs18 304.9 (189.4, 420.4) \cell -\pard\intbl\qc\fs18 -59.3 (-190.7, 72.1) \cell +\pard\intbl\qc\fs18 12/12 (100.0%) \cell +\pard\intbl\qc\fs18 367.1 (287.4, 446.8) \cell +\pard\intbl\qc\fs18 43.6 (-61.7, 148.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -351,11 +351,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 44 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -363,9 +363,9 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -375,9 +375,9 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -387,45 +387,45 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 309.2 (258.7, 359.6) \cell +\pard\intbl\qc\fs18 44/44 (100.0%) \cell +\pard\intbl\qc\fs18 307.2 (250.7, 363.7) \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 49/49 (100.0%) \cell -\pard\intbl\qc\fs18 245.2 (192.5, 297.9) \cell -\pard\intbl\qc\fs18 -69.4 (-141.4, 2.5) \cell +\pard\intbl\qc\fs18 43/43 (100.0%) \cell +\pard\intbl\qc\fs18 259.4 (199.1, 319.7) \cell +\pard\intbl\qc\fs18 -54.3 (-136.0, 27.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 38/38 (100.0%) \cell -\pard\intbl\qc\fs18 327.8 (271.8, 383.9) \cell -\pard\intbl\qc\fs18 21.4 (-61.2, 104.1) \cell +\pard\intbl\qc\fs18 31/31 (100.0%) \cell +\pard\intbl\qc\fs18 356.6 (290.7, 422.5) \cell +\pard\intbl\qc\fs18 62.3 (-38.6, 163.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -435,10 +435,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (ms) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -447,45 +447,45 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 345.6 (293.7, 397.5) \cell +\pard\intbl\qc\fs18 44/44 (100.0%) \cell +\pard\intbl\qc\fs18 313.4 (256.9, 369.9) \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 49/49 (100.0%) \cell -\pard\intbl\qc\fs18 304.8 (257.0, 352.7) \cell -\pard\intbl\qc\fs18 -44.2 (-121.0, 32.6) \cell +\pard\intbl\qc\fs18 43/43 (100.0%) \cell +\pard\intbl\qc\fs18 304.7 (247.7, 361.6) \cell +\pard\intbl\qc\fs18 -15.3 (-98.4, 67.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8872 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2833 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5483 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8955 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 38/38 (100.0%) \cell -\pard\intbl\qc\fs18 289.6 (233.8, 345.4) \cell -\pard\intbl\qc\fs18 -64.8 (-152.3, 22.7) \cell +\pard\intbl\qc\fs18 31/31 (100.0%) \cell +\pard\intbl\qc\fs18 278.5 (221.8, 335.1) \cell +\pard\intbl\qc\fs18 -39.0 (-119.9, 41.8) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2802 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5510 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8872 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2833 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5483 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8955 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -495,9 +495,9 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2833 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5483 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8955 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfecg01apart1/tsfecg01apart1of3.rtf b/tests/testthat/_snaps/tsfecg01apart1/tsfecg01apart1of3.rtf deleted file mode 100644 index 686124d3..00000000 --- a/tests/testthat/_snaps/tsfecg01apart1/tsfecg01apart1of3.rtf +++ /dev/null @@ -1,508 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2802 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5510 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8872 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG01apart1of3:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2802 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5510 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8872 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5510 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8872 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2802 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5510 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8872 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 362.2 (261.5, 463.0) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 296.6 (155.9, 437.3) \cell -\pard\intbl\qc\fs18 -65.6 (-242.5, 111.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 217.0 (58.2, 375.8) \cell -\pard\intbl\qc\fs18 -145.2 (-375.3, 84.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 292.1 (119.9, 464.4) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 325.8 (208.7, 442.8) \cell -\pard\intbl\qc\fs18 33.6 (-181.5, 248.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 358.2 (187.7, 528.8) \cell -\pard\intbl\qc\fs18 66.1 (-146.9, 279.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 311.6 (212.6, 410.7) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 283.4 (193.8, 373.0) \cell -\pard\intbl\qc\fs18 -28.2 (-180.9, 124.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 403.5 (317.5, 489.5) \cell -\pard\intbl\qc\fs18 91.9 (-39.6, 223.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 282.4 (190.0, 374.9) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 348.7 (265.8, 431.5) \cell -\pard\intbl\qc\fs18 66.2 (-68.8, 201.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 354.0 (269.7, 438.3) \cell -\pard\intbl\qc\fs18 71.6 (-26.6, 169.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 308.6 (253.1, 364.2) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 205.1 (133.0, 277.2) \cell -\pard\intbl\qc\fs18 -103.5 (-183.8, -23.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 277.5 (199.0, 356.0) \cell -\pard\intbl\qc\fs18 -31.1 (-134.4, 72.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 319.6 (252.2, 386.9) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 282.3 (217.2, 347.4) \cell -\pard\intbl\qc\fs18 -37.2 (-138.7, 64.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2802 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5510 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8872 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 262.1 (196.4, 327.8) \cell -\pard\intbl\qc\fs18 -57.4 (-148.9, 34.0) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2802 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5510 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8872 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2802 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5510 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8872 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfecg01apart3/tsfecg01apart3of3.rtf b/tests/testthat/_snaps/tsfecg01apart3/tsfecg01apart3of3.rtf deleted file mode 100644 index f4c689be..00000000 --- a/tests/testthat/_snaps/tsfecg01apart3/tsfecg01apart3of3.rtf +++ /dev/null @@ -1,676 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2835 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4357 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6246 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8398 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10550 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG01apart3of3:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2835 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4357 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6246 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8398 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10550 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4357 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6246 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8398 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2835 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4357 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6246 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 307.4 (226.6, 388.2) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 297.7 (112.2, 483.2) \cell -\pard\intbl\qc\fs18 -9.7 (-169.1, 149.7) \cell -\pard\intbl\qc\fs18 -55.9 (-270.3, 158.5) \cell -\pard\intbl\qc\fs18 -12.9 (-328.1, 302.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 279.3 (113.1, 445.4) \cell -\pard\intbl\qc\fs18 -28.1 (-203.2, 146.9) \cell -\pard\intbl\qc\fs18 -117.1 (-379.3, 145.1) \cell -\pard\intbl\qc\fs18 -119.9 (-394.6, 154.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 277.1 (126.5, 427.8) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 274.4 (77.1, 471.8) \cell -\pard\intbl\qc\fs18 -2.7 (-176.6, 171.2) \cell -\pard\intbl\qc\fs18 36.3 (-213.7, 286.4) \cell -\pard\intbl\qc\fs18 -44.1 (-398.8, 310.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 269.7 (124.5, 414.9) \cell -\pard\intbl\qc\fs18 -7.4 (-199.9, 185.0) \cell -\pard\intbl\qc\fs18 73.6 (-184.9, 332.0) \cell -\pard\intbl\qc\fs18 12.0 (-441.9, 466.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 212.2 (129.9, 294.4) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 212.4 (133.5, 291.2) \cell -\pard\intbl\qc\fs18 0.2 (-98.5, 99.0) \cell -\pard\intbl\qc\fs18 -28.4 (-204.4, 147.6) \cell -\pard\intbl\qc\fs18 16.5 (-151.5, 184.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 289.6 (203.6, 375.7) \cell -\pard\intbl\qc\fs18 77.5 (-33.5, 188.5) \cell -\pard\intbl\qc\fs18 14.4 (-151.2, 180.0) \cell -\pard\intbl\qc\fs18 -197.3 (-421.8, 27.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 292.6 (204.9, 380.3) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 329.1 (249.6, 408.6) \cell -\pard\intbl\qc\fs18 36.5 (-56.9, 129.8) \cell -\pard\intbl\qc\fs18 29.8 (-128.8, 188.4) \cell -\pard\intbl\qc\fs18 -149.5 (-302.1, 3.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 301.0 (226.8, 375.2) \cell -\pard\intbl\qc\fs18 8.4 (-106.0, 122.8) \cell -\pard\intbl\qc\fs18 63.2 (-82.0, 208.3) \cell -\pard\intbl\qc\fs18 -67.7 (-232.4, 97.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 33/33 (100.0%) \cell -\pard\intbl\qc\fs18 279.7 (214.2, 345.3) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 32/32 (100.0%) \cell -\pard\intbl\qc\fs18 309.8 (246.5, 373.2) \cell -\pard\intbl\qc\fs18 28.9 (-61.9, 119.7) \cell -\pard\intbl\qc\fs18 -132.4 (-251.1, -13.7) \cell -\pard\intbl\qc\fs18 -98.3 (-212.3, 15.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 30/30 (100.0%) \cell -\pard\intbl\qc\fs18 322.8 (256.1, 389.6) \cell -\pard\intbl\qc\fs18 36.8 (-65.5, 139.1) \cell -\pard\intbl\qc\fs18 -67.9 (-210.1, 74.3) \cell -\pard\intbl\qc\fs18 -15.4 (-144.5, 113.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 33/33 (100.0%) \cell -\pard\intbl\qc\fs18 319.9 (255.7, 384.1) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 32/32 (100.0%) \cell -\pard\intbl\qc\fs18 232.7 (179.0, 286.5) \cell -\pard\intbl\qc\fs18 -79.1 (-171.8, 13.6) \cell -\pard\intbl\qc\fs18 41.9 (-92.7, 176.4) \cell -\pard\intbl\qc\fs18 34.9 (-83.5, 153.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2835 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4357 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6246 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8398 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10550 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 30/30 (100.0%) \cell -\pard\intbl\qc\fs18 212.0 (150.8, 273.2) \cell -\pard\intbl\qc\fs18 -101.9 (-190.8, -13.0) \cell -\pard\intbl\qc\fs18 44.5 (-80.3, 169.2) \cell -\pard\intbl\qc\fs18 37.1 (-85.2, 159.4) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2835 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4357 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6246 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8398 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10550 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4357 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6246 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8398 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10550 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfecg01part1/tsfecg01part1of2.rtf b/tests/testthat/_snaps/tsfecg01part1/tsfecg01part1of2.rtf deleted file mode 100644 index 65eab33e..00000000 --- a/tests/testthat/_snaps/tsfecg01part1/tsfecg01part1of2.rtf +++ /dev/null @@ -1,1498 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2859 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4218 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5906 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7733 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9093 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10780 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG01part1of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2859 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4218 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5906 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7733 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9093 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10780 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx4218 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5906 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7733 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx9093 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx10780 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 317.6 (275.1, 360.1) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73/73 (100.0%) \cell -\pard\intbl\qc\fs18 325.2 (282.7, 367.7) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 242.6 (192.4, 292.7) \cell -\pard\intbl\qc\fs18 -75.1 (-139.6, -10.5) \cell -\pard\intbl\qc\fs18 71/71 (100.0%) \cell -\pard\intbl\qc\fs18 283.9 (239.6, 328.2) \cell -\pard\intbl\qc\fs18 -45.5 (-106.2, 15.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 306.4 (251.3, 361.5) \cell -\pard\intbl\qc\fs18 -11.2 (-86.1, 63.6) \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 302.6 (252.6, 352.5) \cell -\pard\intbl\qc\fs18 -21.2 (-92.9, 50.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 281.3 (237.5, 325.0) \cell -\pard\intbl\qc\fs18 -28.7 (-93.6, 36.2) \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 278.9 (229.3, 328.4) \cell -\pard\intbl\qc\fs18 -56.3 (-128.6, 16.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 283.6 (230.9, 336.2) \cell -\pard\intbl\qc\fs18 -24.8 (-103.7, 54.1) \cell -\pard\intbl\qc\fs18 42/42 (100.0%) \cell -\pard\intbl\qc\fs18 301.3 (245.6, 357.1) \cell -\pard\intbl\qc\fs18 -26.2 (-98.9, 46.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 37/37 (100.0%) \cell -\pard\intbl\qc\fs18 312.9 (258.6, 367.1) \cell -\pard\intbl\qc\fs18 -2.1 (-64.5, 60.3) \cell -\pard\intbl\qc\fs18 35/35 (100.0%) \cell -\pard\intbl\qc\fs18 315.5 (253.9, 377.2) \cell -\pard\intbl\qc\fs18 -2.3 (-92.0, 87.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 27/27 (100.0%) \cell -\pard\intbl\qc\fs18 295.3 (230.3, 360.4) \cell -\pard\intbl\qc\fs18 -4.3 (-95.7, 87.2) \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 286.8 (228.8, 344.8) \cell -\pard\intbl\qc\fs18 -14.2 (-110.3, 81.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 23/23 (100.0%) \cell -\pard\intbl\qc\fs18 308.3 (219.3, 397.3) \cell -\pard\intbl\qc\fs18 26.8 (-90.6, 144.2) \cell -\pard\intbl\qc\fs18 20/20 (100.0%) \cell -\pard\intbl\qc\fs18 294.5 (201.3, 387.7) \cell -\pard\intbl\qc\fs18 -29.4 (-157.4, 98.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 22/22 (100.0%) \cell -\pard\intbl\qc\fs18 283.6 (204.6, 362.7) \cell -\pard\intbl\qc\fs18 -3.7 (-118.7, 111.3) \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 344.3 (250.0, 438.6) \cell -\pard\intbl\qc\fs18 25.9 (-129.3, 181.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 304.2 (255.2, 353.2) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73/73 (100.0%) \cell -\pard\intbl\qc\fs18 346.5 (306.4, 386.6) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 308.9 (264.2, 353.6) \cell -\pard\intbl\qc\fs18 4.7 (-67.2, 76.6) \cell -\pard\intbl\qc\fs18 71/71 (100.0%) \cell -\pard\intbl\qc\fs18 288.0 (247.1, 329.0) \cell -\pard\intbl\qc\fs18 -60.8 (-122.9, 1.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 304.4 (255.7, 353.0) \cell -\pard\intbl\qc\fs18 0.2 (-63.7, 64.0) \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 294.1 (248.1, 340.2) \cell -\pard\intbl\qc\fs18 -57.2 (-128.7, 14.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 302.7 (254.5, 350.9) \cell -\pard\intbl\qc\fs18 -3.0 (-72.8, 66.8) \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 301.0 (243.1, 358.8) \cell -\pard\intbl\qc\fs18 -46.2 (-116.2, 23.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 273.0 (216.0, 330.0) \cell -\pard\intbl\qc\fs18 -35.4 (-115.2, 44.4) \cell -\pard\intbl\qc\fs18 42/42 (100.0%) \cell -\pard\intbl\qc\fs18 317.3 (262.8, 371.8) \cell -\pard\intbl\qc\fs18 -29.7 (-109.4, 50.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 37/37 (100.0%) \cell -\pard\intbl\qc\fs18 249.3 (195.1, 303.6) \cell -\pard\intbl\qc\fs18 -60.2 (-139.3, 18.8) \cell -\pard\intbl\qc\fs18 35/35 (100.0%) \cell -\pard\intbl\qc\fs18 286.8 (232.0, 341.7) \cell -\pard\intbl\qc\fs18 -58.9 (-145.1, 27.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 27/27 (100.0%) \cell -\pard\intbl\qc\fs18 292.3 (219.1, 365.6) \cell -\pard\intbl\qc\fs18 -32.1 (-132.1, 67.8) \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 231.7 (166.3, 297.1) \cell -\pard\intbl\qc\fs18 -106.4 (-193.9, -18.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 23/23 (100.0%) \cell -\pard\intbl\qc\fs18 302.9 (214.7, 391.2) \cell -\pard\intbl\qc\fs18 -34.2 (-154.6, 86.2) \cell -\pard\intbl\qc\fs18 20/20 (100.0%) \cell -\pard\intbl\qc\fs18 331.0 (263.3, 398.6) \cell -\pard\intbl\qc\fs18 21.4 (-96.7, 139.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 22/22 (100.0%) \cell -\pard\intbl\qc\fs18 304.6 (223.8, 385.5) \cell -\pard\intbl\qc\fs18 -41.8 (-166.3, 82.6) \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 274.6 (172.6, 376.7) \cell -\pard\intbl\qc\fs18 -36.5 (-197.5, 124.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 303.0 (257.4, 348.6) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73/73 (100.0%) \cell -\pard\intbl\qc\fs18 305.2 (262.6, 347.8) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 307.3 (261.6, 353.1) \cell -\pard\intbl\qc\fs18 4.3 (-61.1, 69.7) \cell -\pard\intbl\qc\fs18 71/71 (100.0%) \cell -\pard\intbl\qc\fs18 273.4 (233.3, 313.4) \cell -\pard\intbl\qc\fs18 -31.9 (-100.7, 36.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 314.8 (268.1, 361.5) \cell -\pard\intbl\qc\fs18 11.8 (-51.4, 75.0) \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 321.8 (272.3, 371.2) \cell -\pard\intbl\qc\fs18 14.4 (-48.2, 77.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 272.4 (219.7, 325.2) \cell -\pard\intbl\qc\fs18 -25.2 (-90.3, 39.9) \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 287.2 (234.1, 340.3) \cell -\pard\intbl\qc\fs18 -14.4 (-81.7, 53.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 310.9 (259.3, 362.5) \cell -\pard\intbl\qc\fs18 -20.5 (-89.5, 48.4) \cell -\pard\intbl\qc\fs18 42/42 (100.0%) \cell -\pard\intbl\qc\fs18 328.8 (283.2, 374.5) \cell -\pard\intbl\qc\fs18 32.4 (-39.5, 104.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 37/37 (100.0%) \cell -\pard\intbl\qc\fs18 241.8 (181.4, 302.3) \cell -\pard\intbl\qc\fs18 -75.2 (-153.0, 2.7) \cell -\pard\intbl\qc\fs18 35/35 (100.0%) \cell -\pard\intbl\qc\fs18 295.5 (234.7, 356.4) \cell -\pard\intbl\qc\fs18 -5.2 (-89.9, 79.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 27/27 (100.0%) \cell -\pard\intbl\qc\fs18 284.3 (208.5, 360.0) \cell -\pard\intbl\qc\fs18 -36.8 (-117.6, 44.1) \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 268.5 (216.8, 320.1) \cell -\pard\intbl\qc\fs18 -8.2 (-88.1, 71.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 23/23 (100.0%) \cell -\pard\intbl\qc\fs18 277.1 (211.7, 342.6) \cell -\pard\intbl\qc\fs18 -51.3 (-127.4, 24.8) \cell -\pard\intbl\qc\fs18 20/20 (100.0%) \cell -\pard\intbl\qc\fs18 259.6 (169.2, 349.9) \cell -\pard\intbl\qc\fs18 -18.7 (-147.3, 109.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 22/22 (100.0%) \cell -\pard\intbl\qc\fs18 274.2 (200.2, 348.2) \cell -\pard\intbl\qc\fs18 -58.6 (-177.2, 60.0) \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 276.4 (173.8, 378.9) \cell -\pard\intbl\qc\fs18 -17.2 (-142.3, 107.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 361.3 (335.6, 386.9) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73/73 (100.0%) \cell -\pard\intbl\qc\fs18 356.8 (334.4, 379.3) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 361.6 (338.2, 385.0) \cell -\pard\intbl\qc\fs18 0.4 (-30.8, 31.5) \cell -\pard\intbl\qc\fs18 71/71 (100.0%) \cell -\pard\intbl\qc\fs18 397.2 (376.7, 417.8) \cell -\pard\intbl\qc\fs18 39.7 (6.0, 73.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 364.2 (336.5, 391.9) \cell -\pard\intbl\qc\fs18 2.9 (-33.8, 39.7) \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 372.4 (345.9, 398.9) \cell -\pard\intbl\qc\fs18 11.4 (-28.6, 51.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 359.1 (330.0, 388.3) \cell -\pard\intbl\qc\fs18 -0.9 (-36.6, 34.7) \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 356.2 (325.4, 387.1) \cell -\pard\intbl\qc\fs18 -10.8 (-50.8, 29.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 367.9 (339.8, 396.0) \cell -\pard\intbl\qc\fs18 11.1 (-28.7, 51.0) \cell -\pard\intbl\qc\fs18 42/42 (100.0%) \cell -\pard\intbl\qc\fs18 356.4 (325.3, 387.5) \cell -\pard\intbl\qc\fs18 -4.9 (-47.2, 37.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 37/37 (100.0%) \cell -\pard\intbl\qc\fs18 381.6 (346.3, 416.9) \cell -\pard\intbl\qc\fs18 26.5 (-21.1, 74.1) \cell -\pard\intbl\qc\fs18 35/35 (100.0%) \cell -\pard\intbl\qc\fs18 354.4 (317.3, 391.6) \cell -\pard\intbl\qc\fs18 -14.1 (-61.6, 33.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 27/27 (100.0%) \cell -\pard\intbl\qc\fs18 403.8 (372.4, 435.2) \cell -\pard\intbl\qc\fs18 38.6 (-9.5, 86.7) \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 365.9 (334.9, 396.9) \cell -\pard\intbl\qc\fs18 6.3 (-44.5, 57.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 23/23 (100.0%) \cell -\pard\intbl\qc\fs18 375.0 (327.4, 422.6) \cell -\pard\intbl\qc\fs18 19.6 (-36.9, 76.0) \cell -\pard\intbl\qc\fs18 20/20 (100.0%) \cell -\pard\intbl\qc\fs18 363.0 (315.3, 410.8) \cell -\pard\intbl\qc\fs18 16.6 (-52.8, 86.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 22/22 (100.0%) \cell -\pard\intbl\qc\fs18 364.6 (328.6, 400.7) \cell -\pard\intbl\qc\fs18 9.8 (-60.1, 79.6) \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 384.5 (337.7, 431.3) \cell -\pard\intbl\qc\fs18 32.6 (-48.4, 113.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 359.8 (330.1, 389.5) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73/73 (100.0%) \cell -\pard\intbl\qc\fs18 348.7 (326.5, 370.9) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 367.9 (340.5, 395.3) \cell -\pard\intbl\qc\fs18 8.1 (-34.6, 50.8) \cell -\pard\intbl\qc\fs18 71/71 (100.0%) \cell -\pard\intbl\qc\fs18 349.3 (327.7, 370.8) \cell -\pard\intbl\qc\fs18 -1.0 (-31.5, 29.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 361.7 (335.0, 388.3) \cell -\pard\intbl\qc\fs18 1.9 (-30.6, 34.4) \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 364.5 (337.3, 391.7) \cell -\pard\intbl\qc\fs18 14.0 (-21.5, 49.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 355.1 (326.3, 383.9) \cell -\pard\intbl\qc\fs18 -4.6 (-49.4, 40.1) \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 347.7 (320.6, 374.7) \cell -\pard\intbl\qc\fs18 -4.6 (-45.5, 36.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 353.8 (324.4, 383.2) \cell -\pard\intbl\qc\fs18 0.4 (-43.5, 44.4) \cell -\pard\intbl\qc\fs18 42/42 (100.0%) \cell -\pard\intbl\qc\fs18 352.1 (321.6, 382.6) \cell -\pard\intbl\qc\fs18 -2.4 (-44.0, 39.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 37/37 (100.0%) \cell -\pard\intbl\qc\fs18 359.6 (329.8, 389.4) \cell -\pard\intbl\qc\fs18 15.9 (-33.3, 65.2) \cell -\pard\intbl\qc\fs18 35/35 (100.0%) \cell -\pard\intbl\qc\fs18 351.0 (319.0, 383.0) \cell -\pard\intbl\qc\fs18 -1.7 (-43.5, 40.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 27/27 (100.0%) \cell -\pard\intbl\qc\fs18 374.8 (337.9, 411.7) \cell -\pard\intbl\qc\fs18 48.4 (-4.3, 101.1) \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 380.2 (347.4, 412.9) \cell -\pard\intbl\qc\fs18 21.1 (-32.0, 74.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 23/23 (100.0%) \cell -\pard\intbl\qc\fs18 367.6 (329.7, 405.5) \cell -\pard\intbl\qc\fs18 30.8 (-16.0, 77.6) \cell -\pard\intbl\qc\fs18 20/20 (100.0%) \cell -\pard\intbl\qc\fs18 395.6 (348.4, 442.7) \cell -\pard\intbl\qc\fs18 35.0 (-32.1, 102.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 22/22 (100.0%) \cell -\pard\intbl\qc\fs18 358.0 (319.1, 396.8) \cell -\pard\intbl\qc\fs18 19.2 (-50.6, 89.0) \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 406.6 (360.0, 453.3) \cell -\pard\intbl\qc\fs18 44.8 (-30.2, 119.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcF Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 351.6 (324.9, 378.3) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73/73 (100.0%) \cell -\pard\intbl\qc\fs18 347.4 (324.0, 370.8) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 345.1 (318.0, 372.1) \cell -\pard\intbl\qc\fs18 -6.5 (-39.6, 26.6) \cell -\pard\intbl\qc\fs18 71/71 (100.0%) \cell -\pard\intbl\qc\fs18 348.6 (326.9, 370.3) \cell -\pard\intbl\qc\fs18 0.3 (-31.4, 31.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 354.6 (330.0, 379.3) \cell -\pard\intbl\qc\fs18 3.0 (-34.6, 40.7) \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 372.4 (345.1, 399.7) \cell -\pard\intbl\qc\fs18 37.6 (1.6, 73.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 339.7 (310.6, 368.8) \cell -\pard\intbl\qc\fs18 -12.6 (-51.2, 26.0) \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 354.6 (324.9, 384.3) \cell -\pard\intbl\qc\fs18 12.5 (-29.5, 54.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 366.8 (334.7, 398.9) \cell -\pard\intbl\qc\fs18 18.5 (-33.0, 69.9) \cell -\pard\intbl\qc\fs18 42/42 (100.0%) \cell -\pard\intbl\qc\fs18 366.9 (338.4, 395.4) \cell -\pard\intbl\qc\fs18 30.3 (-9.0, 69.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 37/37 (100.0%) \cell -\pard\intbl\qc\fs18 365.1 (335.2, 394.9) \cell -\pard\intbl\qc\fs18 11.4 (-34.6, 57.4) \cell -\pard\intbl\qc\fs18 35/35 (100.0%) \cell -\pard\intbl\qc\fs18 377.8 (346.5, 409.1) \cell -\pard\intbl\qc\fs18 39.4 (-12.5, 91.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 27/27 (100.0%) \cell -\pard\intbl\qc\fs18 383.8 (341.2, 426.4) \cell -\pard\intbl\qc\fs18 24.4 (-36.1, 84.9) \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 326.1 (286.2, 366.1) \cell -\pard\intbl\qc\fs18 -18.6 (-74.0, 36.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 23/23 (100.0%) \cell -\pard\intbl\qc\fs18 333.4 (294.1, 372.8) \cell -\pard\intbl\qc\fs18 -36.9 (-92.3, 18.5) \cell -\pard\intbl\qc\fs18 20/20 (100.0%) \cell -\pard\intbl\qc\fs18 375.0 (328.6, 421.3) \cell -\pard\intbl\qc\fs18 6.7 (-63.2, 76.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 22/22 (100.0%) \cell -\pard\intbl\qc\fs18 379.0 (334.0, 424.0) \cell -\pard\intbl\qc\fs18 13.8 (-41.1, 68.7) \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 380.6 (330.8, 430.5) \cell -\pard\intbl\qc\fs18 -3.4 (-56.9, 50.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 RR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 313.7 (269.4, 357.9) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73/73 (100.0%) \cell -\pard\intbl\qc\fs18 281.0 (241.4, 320.6) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 250.6 (206.9, 294.4) \cell -\pard\intbl\qc\fs18 -63.0 (-122.1, -4.0) \cell -\pard\intbl\qc\fs18 71/71 (100.0%) \cell -\pard\intbl\qc\fs18 320.7 (280.1, 361.3) \cell -\pard\intbl\qc\fs18 35.5 (-21.8, 92.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 311.0 (266.0, 356.1) \cell -\pard\intbl\qc\fs18 -2.6 (-67.2, 62.0) \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 310.6 (258.3, 362.8) \cell -\pard\intbl\qc\fs18 19.2 (-47.0, 85.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 262.0 (218.0, 306.1) \cell -\pard\intbl\qc\fs18 -46.5 (-117.2, 24.2) \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 307.1 (256.2, 358.1) \cell -\pard\intbl\qc\fs18 11.6 (-61.6, 84.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 374.7 (325.8, 423.6) \cell -\pard\intbl\qc\fs18 61.7 (-15.3, 138.6) \cell -\pard\intbl\qc\fs18 42/42 (100.0%) \cell -\pard\intbl\qc\fs18 319.8 (270.3, 369.3) \cell -\pard\intbl\qc\fs18 26.1 (-43.9, 96.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 37/37 (100.0%) \cell -\pard\intbl\qc\fs18 214.6 (166.2, 263.0) \cell -\pard\intbl\qc\fs18 -98.3 (-174.0, -22.5) \cell -\pard\intbl\qc\fs18 35/35 (100.0%) \cell -\pard\intbl\qc\fs18 293.0 (232.3, 353.7) \cell -\pard\intbl\qc\fs18 7.7 (-62.5, 77.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 27/27 (100.0%) \cell -\pard\intbl\qc\fs18 297.4 (225.4, 369.4) \cell -\pard\intbl\qc\fs18 -8.4 (-85.9, 69.0) \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 329.7 (265.8, 393.6) \cell -\pard\intbl\qc\fs18 37.1 (-57.4, 131.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 23/23 (100.0%) \cell -\pard\intbl\qc\fs18 289.6 (212.9, 366.3) \cell -\pard\intbl\qc\fs18 -32.9 (-138.6, 72.9) \cell -\pard\intbl\qc\fs18 20/20 (100.0%) \cell -\pard\intbl\qc\fs18 270.6 (203.8, 337.5) \cell -\pard\intbl\qc\fs18 -20.5 (-101.8, 60.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4218 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5906 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7733 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9093 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10780 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 22/22 (100.0%) \cell -\pard\intbl\qc\fs18 319.0 (234.7, 403.4) \cell -\pard\intbl\qc\fs18 4.3 (-85.6, 94.2) \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 314.3 (236.3, 392.3) \cell -\pard\intbl\qc\fs18 14.9 (-106.5, 136.3) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4218 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5906 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7733 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9093 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10780 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4218 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5906 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7733 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9093 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10780 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfecg01part2/tsfecg01part2of2.rtf b/tests/testthat/_snaps/tsfecg01part2/tsfecg01part2of2.rtf deleted file mode 100644 index 09a65c32..00000000 --- a/tests/testthat/_snaps/tsfecg01part2/tsfecg01part2of2.rtf +++ /dev/null @@ -1,1332 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2841 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4395 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6324 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8307 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10504 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG01part2of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2841 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4395 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6324 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8307 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10504 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4395 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6324 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8307 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2841 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4395 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6324 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 59/59 (100.0%) \cell -\pard\intbl\qc\fs18 261.3 (216.2, 306.3) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 58/58 (100.0%) \cell -\pard\intbl\qc\fs18 276.4 (229.7, 323.1) \cell -\pard\intbl\qc\fs18 14.8 (-44.6, 74.3) \cell -\pard\intbl\qc\fs18 -89.9 (-176.7, -3.1) \cell -\pard\intbl\qc\fs18 -60.3 (-144.5, 23.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 56/56 (100.0%) \cell -\pard\intbl\qc\fs18 306.1 (258.9, 353.4) \cell -\pard\intbl\qc\fs18 42.5 (-24.1, 109.1) \cell -\pard\intbl\qc\fs18 -53.7 (-152.8, 45.4) \cell -\pard\intbl\qc\fs18 -63.7 (-160.4, 33.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 293.7 (243.4, 344.1) \cell -\pard\intbl\qc\fs18 22.9 (-51.2, 96.9) \cell -\pard\intbl\qc\fs18 -51.6 (-148.9, 45.7) \cell -\pard\intbl\qc\fs18 -79.2 (-181.3, 23.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 331.6 (281.3, 381.9) \cell -\pard\intbl\qc\fs18 60.7 (-20.7, 142.2) \cell -\pard\intbl\qc\fs18 -85.5 (-197.4, 26.3) \cell -\pard\intbl\qc\fs18 -86.9 (-194.6, 20.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 48/48 (100.0%) \cell -\pard\intbl\qc\fs18 313.2 (262.7, 363.6) \cell -\pard\intbl\qc\fs18 39.7 (-23.9, 103.4) \cell -\pard\intbl\qc\fs18 -41.9 (-129.7, 45.9) \cell -\pard\intbl\qc\fs18 -42.0 (-150.5, 66.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 278.2 (231.6, 324.8) \cell -\pard\intbl\qc\fs18 2.4 (-74.7, 79.4) \cell -\pard\intbl\qc\fs18 -6.6 (-124.1, 110.8) \cell -\pard\intbl\qc\fs18 -16.6 (-137.6, 104.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 45/45 (100.0%) \cell -\pard\intbl\qc\fs18 278.2 (232.8, 323.7) \cell -\pard\intbl\qc\fs18 -1.7 (-66.2, 62.9) \cell -\pard\intbl\qc\fs18 28.4 (-103.4, 160.3) \cell -\pard\intbl\qc\fs18 -27.8 (-168.7, 113.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 311.8 (256.6, 367.0) \cell -\pard\intbl\qc\fs18 33.1 (-41.6, 107.9) \cell -\pard\intbl\qc\fs18 -36.8 (-171.3, 97.6) \cell -\pard\intbl\qc\fs18 -7.2 (-176.1, 161.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 59/59 (100.0%) \cell -\pard\intbl\qc\fs18 306.1 (259.9, 352.2) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 58/58 (100.0%) \cell -\pard\intbl\qc\fs18 269.3 (225.8, 312.9) \cell -\pard\intbl\qc\fs18 -32.0 (-93.4, 29.3) \cell -\pard\intbl\qc\fs18 36.7 (-56.7, 130.2) \cell -\pard\intbl\qc\fs18 -28.8 (-115.2, 57.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 56/56 (100.0%) \cell -\pard\intbl\qc\fs18 249.4 (205.9, 292.9) \cell -\pard\intbl\qc\fs18 -52.7 (-116.0, 10.6) \cell -\pard\intbl\qc\fs18 52.8 (-36.1, 141.7) \cell -\pard\intbl\qc\fs18 -4.5 (-98.9, 89.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 271.3 (225.4, 317.3) \cell -\pard\intbl\qc\fs18 -24.7 (-89.9, 40.4) \cell -\pard\intbl\qc\fs18 21.7 (-72.5, 116.0) \cell -\pard\intbl\qc\fs18 -21.4 (-115.9, 73.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 279.4 (234.9, 324.0) \cell -\pard\intbl\qc\fs18 -16.6 (-83.4, 50.1) \cell -\pard\intbl\qc\fs18 -18.7 (-121.4, 83.9) \cell -\pard\intbl\qc\fs18 -13.0 (-115.6, 89.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 48/48 (100.0%) \cell -\pard\intbl\qc\fs18 271.8 (220.7, 322.9) \cell -\pard\intbl\qc\fs18 -26.0 (-107.7, 55.7) \cell -\pard\intbl\qc\fs18 -34.2 (-146.2, 77.8) \cell -\pard\intbl\qc\fs18 -32.8 (-149.8, 84.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 311.6 (255.0, 368.1) \cell -\pard\intbl\qc\fs18 13.6 (-55.9, 83.1) \cell -\pard\intbl\qc\fs18 -45.7 (-165.4, 74.0) \cell -\pard\intbl\qc\fs18 -120.0 (-229.8, -10.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 45/45 (100.0%) \cell -\pard\intbl\qc\fs18 312.1 (261.2, 363.0) \cell -\pard\intbl\qc\fs18 22.4 (-49.8, 94.5) \cell -\pard\intbl\qc\fs18 -56.6 (-194.5, 81.3) \cell -\pard\intbl\qc\fs18 -1.0 (-136.6, 134.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 260.3 (205.8, 314.9) \cell -\pard\intbl\qc\fs18 -18.2 (-107.3, 70.8) \cell -\pard\intbl\qc\fs18 -23.6 (-173.5, 126.3) \cell -\pard\intbl\qc\fs18 -18.3 (-198.1, 161.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QRS Duration, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 59/59 (100.0%) \cell -\pard\intbl\qc\fs18 299.3 (254.7, 343.9) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 58/58 (100.0%) \cell -\pard\intbl\qc\fs18 299.1 (253.4, 344.8) \cell -\pard\intbl\qc\fs18 4.2 (-56.3, 64.8) \cell -\pard\intbl\qc\fs18 0.1 (-88.0, 88.2) \cell -\pard\intbl\qc\fs18 -36.1 (-126.9, 54.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 56/56 (100.0%) \cell -\pard\intbl\qc\fs18 247.0 (197.2, 296.8) \cell -\pard\intbl\qc\fs18 -46.4 (-117.4, 24.6) \cell -\pard\intbl\qc\fs18 58.1 (-35.8, 152.1) \cell -\pard\intbl\qc\fs18 60.8 (-32.8, 154.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 275.9 (226.7, 325.2) \cell -\pard\intbl\qc\fs18 -13.8 (-82.0, 54.4) \cell -\pard\intbl\qc\fs18 -11.4 (-104.6, 81.8) \cell -\pard\intbl\qc\fs18 -0.6 (-95.2, 94.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 293.6 (249.7, 337.6) \cell -\pard\intbl\qc\fs18 3.9 (-62.9, 70.8) \cell -\pard\intbl\qc\fs18 -24.5 (-119.2, 70.3) \cell -\pard\intbl\qc\fs18 28.5 (-68.4, 125.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 48/48 (100.0%) \cell -\pard\intbl\qc\fs18 293.6 (242.5, 344.6) \cell -\pard\intbl\qc\fs18 6.2 (-67.3, 79.7) \cell -\pard\intbl\qc\fs18 -81.4 (-186.8, 24.1) \cell -\pard\intbl\qc\fs18 -11.4 (-121.8, 99.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 290.3 (240.6, 339.9) \cell -\pard\intbl\qc\fs18 2.7 (-71.4, 76.8) \cell -\pard\intbl\qc\fs18 -39.5 (-147.1, 68.2) \cell -\pard\intbl\qc\fs18 -10.9 (-118.0, 96.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 45/45 (100.0%) \cell -\pard\intbl\qc\fs18 332.1 (284.5, 379.7) \cell -\pard\intbl\qc\fs18 48.0 (-20.7, 116.8) \cell -\pard\intbl\qc\fs18 -99.3 (-199.7, 1.1) \cell -\pard\intbl\qc\fs18 -66.7 (-210.0, 76.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 302.9 (247.7, 358.0) \cell -\pard\intbl\qc\fs18 29.2 (-52.6, 111.0) \cell -\pard\intbl\qc\fs18 -87.8 (-228.9, 53.3) \cell -\pard\intbl\qc\fs18 -46.4 (-192.0, 99.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 59/59 (100.0%) \cell -\pard\intbl\qc\fs18 362.7 (337.2, 388.3) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 58/58 (100.0%) \cell -\pard\intbl\qc\fs18 368.3 (344.6, 392.0) \cell -\pard\intbl\qc\fs18 6.8 (-22.5, 36.2) \cell -\pard\intbl\qc\fs18 -6.5 (-48.8, 35.8) \cell -\pard\intbl\qc\fs18 32.9 (-11.4, 77.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 56/56 (100.0%) \cell -\pard\intbl\qc\fs18 355.2 (332.0, 378.5) \cell -\pard\intbl\qc\fs18 -6.4 (-43.3, 30.6) \cell -\pard\intbl\qc\fs18 9.3 (-42.2, 60.8) \cell -\pard\intbl\qc\fs18 17.8 (-36.1, 71.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 333.6 (306.3, 361.0) \cell -\pard\intbl\qc\fs18 -23.2 (-63.8, 17.5) \cell -\pard\intbl\qc\fs18 22.2 (-31.2, 75.6) \cell -\pard\intbl\qc\fs18 12.4 (-43.9, 68.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 365.0 (340.2, 389.7) \cell -\pard\intbl\qc\fs18 8.2 (-27.8, 44.2) \cell -\pard\intbl\qc\fs18 2.9 (-50.0, 55.9) \cell -\pard\intbl\qc\fs18 -13.0 (-67.9, 41.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 48/48 (100.0%) \cell -\pard\intbl\qc\fs18 377.1 (350.4, 403.9) \cell -\pard\intbl\qc\fs18 22.6 (-14.7, 59.9) \cell -\pard\intbl\qc\fs18 4.0 (-55.6, 63.6) \cell -\pard\intbl\qc\fs18 -36.6 (-96.1, 22.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 401.4 (375.9, 427.0) \cell -\pard\intbl\qc\fs18 49.2 (13.6, 84.8) \cell -\pard\intbl\qc\fs18 -10.6 (-69.4, 48.2) \cell -\pard\intbl\qc\fs18 -42.9 (-103.9, 18.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 45/45 (100.0%) \cell -\pard\intbl\qc\fs18 371.8 (342.6, 400.9) \cell -\pard\intbl\qc\fs18 23.4 (-14.0, 60.7) \cell -\pard\intbl\qc\fs18 -3.8 (-70.2, 62.7) \cell -\pard\intbl\qc\fs18 -6.8 (-84.2, 70.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 351.2 (320.6, 381.9) \cell -\pard\intbl\qc\fs18 3.5 (-34.4, 41.4) \cell -\pard\intbl\qc\fs18 6.3 (-71.9, 84.4) \cell -\pard\intbl\qc\fs18 29.1 (-58.6, 116.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 59/59 (100.0%) \cell -\pard\intbl\qc\fs18 368.6 (343.9, 393.3) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 58/58 (100.0%) \cell -\pard\intbl\qc\fs18 368.1 (342.7, 393.5) \cell -\pard\intbl\qc\fs18 1.9 (-34.6, 38.3) \cell -\pard\intbl\qc\fs18 6.3 (-49.3, 61.8) \cell -\pard\intbl\qc\fs18 -2.8 (-49.9, 44.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 56/56 (100.0%) \cell -\pard\intbl\qc\fs18 361.4 (337.5, 385.3) \cell -\pard\intbl\qc\fs18 -8.4 (-43.0, 26.1) \cell -\pard\intbl\qc\fs18 10.3 (-36.5, 57.2) \cell -\pard\intbl\qc\fs18 22.5 (-26.5, 71.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 352.5 (326.3, 378.6) \cell -\pard\intbl\qc\fs18 -22.8 (-59.4, 13.9) \cell -\pard\intbl\qc\fs18 18.2 (-39.0, 75.3) \cell -\pard\intbl\qc\fs18 18.2 (-36.0, 72.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 370.1 (345.1, 395.0) \cell -\pard\intbl\qc\fs18 -5.2 (-35.7, 25.3) \cell -\pard\intbl\qc\fs18 5.6 (-47.3, 58.4) \cell -\pard\intbl\qc\fs18 2.8 (-48.1, 53.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 48/48 (100.0%) \cell -\pard\intbl\qc\fs18 364.6 (338.0, 391.3) \cell -\pard\intbl\qc\fs18 -10.3 (-48.7, 28.2) \cell -\pard\intbl\qc\fs18 26.2 (-35.3, 87.8) \cell -\pard\intbl\qc\fs18 8.6 (-47.3, 64.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 383.9 (356.7, 411.0) \cell -\pard\intbl\qc\fs18 10.4 (-28.7, 49.5) \cell -\pard\intbl\qc\fs18 38.0 (-26.5, 102.5) \cell -\pard\intbl\qc\fs18 10.7 (-54.2, 75.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 45/45 (100.0%) \cell -\pard\intbl\qc\fs18 375.3 (343.6, 406.9) \cell -\pard\intbl\qc\fs18 3.9 (-41.2, 49.0) \cell -\pard\intbl\qc\fs18 26.9 (-36.7, 90.5) \cell -\pard\intbl\qc\fs18 31.1 (-48.0, 110.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 362.6 (332.9, 392.2) \cell -\pard\intbl\qc\fs18 -17.8 (-55.9, 20.3) \cell -\pard\intbl\qc\fs18 37.0 (-41.2, 115.2) \cell -\pard\intbl\qc\fs18 62.6 (-19.8, 145.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcF Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 59/59 (100.0%) \cell -\pard\intbl\qc\fs18 367.4 (342.5, 392.4) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 58/58 (100.0%) \cell -\pard\intbl\qc\fs18 361.9 (337.2, 386.7) \cell -\pard\intbl\qc\fs18 -8.2 (-41.2, 24.8) \cell -\pard\intbl\qc\fs18 1.7 (-44.5, 47.9) \cell -\pard\intbl\qc\fs18 8.5 (-36.8, 53.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 56/56 (100.0%) \cell -\pard\intbl\qc\fs18 374.9 (350.7, 399.1) \cell -\pard\intbl\qc\fs18 5.5 (-30.8, 41.9) \cell -\pard\intbl\qc\fs18 -2.5 (-54.2, 49.2) \cell -\pard\intbl\qc\fs18 32.1 (-18.5, 82.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 357.2 (328.1, 386.3) \cell -\pard\intbl\qc\fs18 -5.9 (-42.7, 31.0) \cell -\pard\intbl\qc\fs18 -6.8 (-59.5, 46.0) \cell -\pard\intbl\qc\fs18 18.4 (-36.8, 73.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 364.4 (336.0, 392.7) \cell -\pard\intbl\qc\fs18 1.3 (-38.4, 41.1) \cell -\pard\intbl\qc\fs18 17.1 (-47.1, 81.3) \cell -\pard\intbl\qc\fs18 29.0 (-26.2, 84.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 48/48 (100.0%) \cell -\pard\intbl\qc\fs18 351.7 (324.8, 378.6) \cell -\pard\intbl\qc\fs18 -10.5 (-48.6, 27.6) \cell -\pard\intbl\qc\fs18 21.9 (-37.0, 80.8) \cell -\pard\intbl\qc\fs18 49.9 (-13.6, 113.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 340.2 (310.0, 370.4) \cell -\pard\intbl\qc\fs18 -18.7 (-60.9, 23.4) \cell -\pard\intbl\qc\fs18 43.2 (-29.4, 115.7) \cell -\pard\intbl\qc\fs18 0.2 (-68.3, 68.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 45/45 (100.0%) \cell -\pard\intbl\qc\fs18 367.6 (337.4, 397.7) \cell -\pard\intbl\qc\fs18 6.6 (-27.4, 40.6) \cell -\pard\intbl\qc\fs18 -43.5 (-107.3, 20.4) \cell -\pard\intbl\qc\fs18 0.1 (-76.4, 76.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 359.7 (328.7, 390.7) \cell -\pard\intbl\qc\fs18 2.3 (-35.4, 40.1) \cell -\pard\intbl\qc\fs18 11.5 (-53.8, 76.8) \cell -\pard\intbl\qc\fs18 -5.7 (-69.4, 58.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 RR Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 59/59 (100.0%) \cell -\pard\intbl\qc\fs18 310.4 (268.7, 352.2) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 58/58 (100.0%) \cell -\pard\intbl\qc\fs18 288.3 (245.3, 331.3) \cell -\pard\intbl\qc\fs18 -17.7 (-76.3, 40.9) \cell -\pard\intbl\qc\fs18 -45.3 (-127.6, 36.9) \cell -\pard\intbl\qc\fs18 53.2 (-28.0, 134.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 56/56 (100.0%) \cell -\pard\intbl\qc\fs18 290.0 (248.1, 332.0) \cell -\pard\intbl\qc\fs18 -18.8 (-69.4, 31.9) \cell -\pard\intbl\qc\fs18 16.1 (-65.1, 97.3) \cell -\pard\intbl\qc\fs18 38.0 (-44.5, 120.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 331.8 (283.1, 380.6) \cell -\pard\intbl\qc\fs18 26.7 (-49.1, 102.6) \cell -\pard\intbl\qc\fs18 -73.3 (-175.7, 29.2) \cell -\pard\intbl\qc\fs18 -15.1 (-119.2, 88.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 300.7 (252.1, 349.4) \cell -\pard\intbl\qc\fs18 -4.3 (-70.9, 62.3) \cell -\pard\intbl\qc\fs18 66.0 (-34.4, 166.4) \cell -\pard\intbl\qc\fs18 30.5 (-64.8, 125.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 48/48 (100.0%) \cell -\pard\intbl\qc\fs18 346.4 (298.9, 393.8) \cell -\pard\intbl\qc\fs18 41.7 (-15.5, 99.0) \cell -\pard\intbl\qc\fs18 -140.0 (-233.6, -46.4) \cell -\pard\intbl\qc\fs18 -34.0 (-123.2, 55.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 337.6 (289.9, 385.3) \cell -\pard\intbl\qc\fs18 32.9 (-30.6, 96.5) \cell -\pard\intbl\qc\fs18 -41.4 (-139.7, 57.0) \cell -\pard\intbl\qc\fs18 4.2 (-108.0, 116.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell -\pard\intbl\qc\fs18 45/45 (100.0%) \cell -\pard\intbl\qc\fs18 310.0 (255.1, 364.8) \cell -\pard\intbl\qc\fs18 9.3 (-62.7, 81.3) \cell -\pard\intbl\qc\fs18 -42.2 (-167.7, 83.4) \cell -\pard\intbl\qc\fs18 -29.8 (-135.8, 76.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2841 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4395 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6324 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8307 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10504 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell -\pard\intbl\qc\fs18 41/41 (100.0%) \cell -\pard\intbl\qc\fs18 328.9 (280.2, 377.6) \cell -\pard\intbl\qc\fs18 27.4 (-42.3, 97.2) \cell -\pard\intbl\qc\fs18 -23.2 (-134.5, 88.1) \cell -\pard\intbl\qc\fs18 -12.6 (-149.3, 124.1) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2841 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4395 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6324 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8307 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10504 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2841 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4395 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6324 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8307 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10504 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfecg02/tsfecg02.rtf b/tests/testthat/_snaps/tsfecg02/tsfecg02.rtf old mode 100755 new mode 100644 index 7981b109..9d53ebbc --- a/tests/testthat/_snaps/tsfecg02/tsfecg02.rtf +++ b/tests/testthat/_snaps/tsfecg02/tsfecg02.rtf @@ -3,323 +3,69 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG02:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2828 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7069 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2863 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7608 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr QTc Interval \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li270\fi0 Criteria, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QT Interval, Corrected (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 42 (79.2%) \cell -\pard\intbl\qc\fs18 54 (74.0%) \cell -\pard\intbl\qc\fs18 42 (71.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 10 (13.7%) \cell -\pard\intbl\qc\fs18 8 (13.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 50 (70.4%) \cell -\pard\intbl\qc\fs18 42 (72.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.8%) \cell -\pard\intbl\qc\fs18 8 (13.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 7 (9.9%) \cell -\pard\intbl\qc\fs18 3 (5.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 12 (16.9%) \cell -\pard\intbl\qc\fs18 5 (8.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 56 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 40 (75.5%) \cell -\pard\intbl\qc\fs18 37 (69.8%) \cell -\pard\intbl\qc\fs18 46 (82.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 5 (8.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (5.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 2 (3.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Criteria, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcB Interval, Aggregate (ms) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell -\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -327,82 +73,12 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 47 \cell -\pard\intbl\qc\fs18 51 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 36 (70.6%) \cell -\pard\intbl\qc\fs18 35 (74.5%) \cell -\pard\intbl\qc\fs18 43 (84.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 9 (17.6%) \cell -\pard\intbl\qc\fs18 3 (6.4%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 3 (6.4%) \cell -\pard\intbl\qc\fs18 1 (2.0%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 6 (12.8%) \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell \pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -411,178 +87,96 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 41 \cell -\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 67 \cell \pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 31 (75.6%) \cell -\pard\intbl\qc\fs18 32 (76.2%) \cell -\pard\intbl\qc\fs18 41 (80.4%) \cell +\pard\intbl\qc\fs18 54 (80.6%) \cell +\pard\intbl\qc\fs18 37 (72.5%) \cell +\pard\intbl\qc\fs18 91 (77.1%) \cell +\pard\intbl\qc\fs18 53 (82.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 4 (9.8%) \cell -\pard\intbl\qc\fs18 4 (9.5%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell \pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 1 (2.4%) \cell -\pard\intbl\qc\fs18 2 (4.8%) \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 5 (12.2%) \cell -\pard\intbl\qc\fs18 4 (9.5%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 37 \cell -\pard\intbl\qc\fs18 35 \cell -\pard\intbl\qc\fs18 48 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 25 (67.6%) \cell -\pard\intbl\qc\fs18 26 (74.3%) \cell -\pard\intbl\qc\fs18 35 (72.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 4 (10.8%) \cell -\pard\intbl\qc\fs18 4 (11.4%) \cell -\pard\intbl\qc\fs18 5 (10.4%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 2 (5.4%) \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell -\pard\intbl\qc\fs18 4 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 6 (16.2%) \cell -\pard\intbl\qc\fs18 4 (11.4%) \cell -\pard\intbl\qc\fs18 4 (8.3%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcB Interval, Aggregate (msec) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell \pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -591,502 +185,488 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 37 (69.8%) \cell -\pard\intbl\qc\fs18 58 (79.5%) \cell -\pard\intbl\qc\fs18 46 (78.0%) \cell +\pard\intbl\qc\fs18 55 (83.3%) \cell +\pard\intbl\qc\fs18 40 (78.4%) \cell +\pard\intbl\qc\fs18 95 (81.2%) \cell +\pard\intbl\qc\fs18 43 (69.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell +\pard\intbl\qc\fs18 5 (7.6%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 13 (11.1%) \cell +\pard\intbl\qc\fs18 9 (14.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.3%) \cell +\pard\intbl\qc\fs18 4 (6.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 6 (9.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 38 (71.7%) \cell -\pard\intbl\qc\fs18 60 (84.5%) \cell -\pard\intbl\qc\fs18 41 (70.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 3 (4.2%) \cell -\pard\intbl\qc\fs18 10 (17.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 5 (7.0%) \cell -\pard\intbl\qc\fs18 3 (5.2%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.2%) \cell -\pard\intbl\qc\fs18 4 (6.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 41 (77.4%) \cell -\pard\intbl\qc\fs18 38 (71.7%) \cell -\pard\intbl\qc\fs18 47 (83.9%) \cell +\pard\intbl\qc\fs18 33 (70.2%) \cell +\pard\intbl\qc\fs18 37 (72.5%) \cell +\pard\intbl\qc\fs18 70 (71.4%) \cell +\pard\intbl\qc\fs18 51 (83.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 4 (7.1%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 10 (10.2%) \cell +\pard\intbl\qc\fs18 6 (9.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 2 (3.6%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 11 (11.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (5.4%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 7 (7.1%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 42 \cell \pard\intbl\qc\fs18 47 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 37 (72.5%) \cell -\pard\intbl\qc\fs18 40 (85.1%) \cell -\pard\intbl\qc\fs18 42 (82.4%) \cell +\pard\intbl\qc\fs18 35 (83.3%) \cell +\pard\intbl\qc\fs18 35 (74.5%) \cell +\pard\intbl\qc\fs18 70 (78.7%) \cell +\pard\intbl\qc\fs18 47 (85.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 6 (11.8%) \cell -\pard\intbl\qc\fs18 2 (4.3%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (7.1%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 8 (9.0%) \cell +\pard\intbl\qc\fs18 4 (7.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell -\pard\intbl\qc\fs18 3 (6.4%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (4.8%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 7 (7.9%) \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (4.8%) \cell \pard\intbl\qc\fs18 2 (4.3%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 41 \cell -\pard\intbl\qc\fs18 42 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 33 (80.5%) \cell -\pard\intbl\qc\fs18 33 (78.6%) \cell -\pard\intbl\qc\fs18 41 (80.4%) \cell +\pard\intbl\qc\fs18 32 (82.1%) \cell +\pard\intbl\qc\fs18 30 (76.9%) \cell +\pard\intbl\qc\fs18 62 (79.5%) \cell +\pard\intbl\qc\fs18 42 (80.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 4 (9.8%) \cell -\pard\intbl\qc\fs18 5 (11.9%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (12.8%) \cell +\pard\intbl\qc\fs18 5 (12.8%) \cell +\pard\intbl\qc\fs18 10 (12.8%) \cell +\pard\intbl\qc\fs18 4 (7.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 2 (4.9%) \cell -\pard\intbl\qc\fs18 1 (2.4%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 4 (5.1%) \cell +\pard\intbl\qc\fs18 4 (7.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 2 (4.9%) \cell -\pard\intbl\qc\fs18 3 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (2.6%) \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 34 \cell \pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell \pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 33 (89.2%) \cell -\pard\intbl\qc\fs18 29 (82.9%) \cell +\pard\intbl\qc\fs18 29 (85.3%) \cell +\pard\intbl\qc\fs18 28 (80.0%) \cell +\pard\intbl\qc\fs18 57 (82.6%) \cell \pard\intbl\qc\fs18 37 (77.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 1 (2.7%) \cell -\pard\intbl\qc\fs18 3 (8.6%) \cell -\pard\intbl\qc\fs18 8 (16.7%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 2 (5.7%) \cell +\pard\intbl\qc\fs18 4 (5.8%) \cell +\pard\intbl\qc\fs18 7 (14.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 2 (5.4%) \cell +\pard\intbl\qc\fs18 3 (8.8%) \cell \pard\intbl\qc\fs18 2 (5.7%) \cell -\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 5 (7.2%) \cell +\pard\intbl\qc\fs18 2 (4.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 1 (2.7%) \cell -\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (8.6%) \cell +\pard\intbl\qc\fs18 3 (4.3%) \cell \pard\intbl\qc\fs18 2 (4.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcF Interval, Aggregate (msec) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcF Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1095,517 +675,603 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 44 (83.0%) \cell -\pard\intbl\qc\fs18 59 (80.8%) \cell -\pard\intbl\qc\fs18 42 (71.2%) \cell +\pard\intbl\qc\fs18 52 (77.6%) \cell +\pard\intbl\qc\fs18 43 (84.3%) \cell +\pard\intbl\qc\fs18 95 (80.5%) \cell +\pard\intbl\qc\fs18 42 (65.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 9 (15.3%) \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 42 (79.2%) \cell -\pard\intbl\qc\fs18 57 (80.3%) \cell -\pard\intbl\qc\fs18 49 (84.5%) \cell +\pard\intbl\qc\fs18 55 (83.3%) \cell +\pard\intbl\qc\fs18 41 (80.4%) \cell +\pard\intbl\qc\fs18 96 (82.1%) \cell +\pard\intbl\qc\fs18 54 (87.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 8 (11.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 7 (10.6%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.6%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.6%) \cell -\pard\intbl\qc\fs18 6 (10.3%) \cell +\pard\intbl\qc\fs18 4 (6.1%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 7 (6.0%) \cell +\pard\intbl\qc\fs18 5 (8.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 42 (79.2%) \cell -\pard\intbl\qc\fs18 40 (75.5%) \cell -\pard\intbl\qc\fs18 43 (76.8%) \cell +\pard\intbl\qc\fs18 39 (83.0%) \cell +\pard\intbl\qc\fs18 43 (84.3%) \cell +\pard\intbl\qc\fs18 82 (83.7%) \cell +\pard\intbl\qc\fs18 49 (80.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (3.6%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 5 (8.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 5 (8.9%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (9.2%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 6 (10.7%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 5 (8.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 42 \cell \pard\intbl\qc\fs18 47 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 42 (82.4%) \cell -\pard\intbl\qc\fs18 37 (78.7%) \cell -\pard\intbl\qc\fs18 36 (70.6%) \cell +\pard\intbl\qc\fs18 33 (78.6%) \cell +\pard\intbl\qc\fs18 42 (89.4%) \cell +\pard\intbl\qc\fs18 75 (84.3%) \cell +\pard\intbl\qc\fs18 36 (65.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 2 (4.8%) \cell \pard\intbl\qc\fs18 2 (4.3%) \cell -\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 4 (4.5%) \cell +\pard\intbl\qc\fs18 6 (10.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell \pard\intbl\qc\fs18 1 (2.1%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 4 (7.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell -\pard\intbl\qc\fs18 7 (14.9%) \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (14.3%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 8 (9.0%) \cell +\pard\intbl\qc\fs18 9 (16.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 41 \cell -\pard\intbl\qc\fs18 42 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 32 (78.0%) \cell -\pard\intbl\qc\fs18 36 (85.7%) \cell -\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 34 (87.2%) \cell +\pard\intbl\qc\fs18 29 (74.4%) \cell +\pard\intbl\qc\fs18 63 (80.8%) \cell +\pard\intbl\qc\fs18 40 (76.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 2 (4.9%) \cell -\pard\intbl\qc\fs18 1 (2.4%) \cell -\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 4 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 3 (7.3%) \cell -\pard\intbl\qc\fs18 3 (7.1%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 4 (5.1%) \cell +\pard\intbl\qc\fs18 4 (7.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 4 (9.8%) \cell -\pard\intbl\qc\fs18 2 (4.8%) \cell -\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 5 (12.8%) \cell +\pard\intbl\qc\fs18 7 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 34 \cell \pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell \pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 30 (81.1%) \cell -\pard\intbl\qc\fs18 27 (77.1%) \cell -\pard\intbl\qc\fs18 38 (79.2%) \cell +\pard\intbl\qc\fs18 24 (70.6%) \cell +\pard\intbl\qc\fs18 29 (82.9%) \cell +\pard\intbl\qc\fs18 53 (76.8%) \cell +\pard\intbl\qc\fs18 34 (70.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell -\pard\intbl\qc\fs18 2 (5.4%) \cell -\pard\intbl\qc\fs18 4 (11.4%) \cell -\pard\intbl\qc\fs18 7 (14.6%) \cell +\pard\intbl\qc\fs18 5 (14.7%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 6 (8.7%) \cell +\pard\intbl\qc\fs18 9 (18.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell -\pard\intbl\qc\fs18 3 (8.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (4.2%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 3 (8.6%) \cell +\pard\intbl\qc\fs18 4 (5.8%) \cell +\pard\intbl\qc\fs18 5 (10.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell -\pard\intbl\qc\fs18 2 (5.4%) \cell -\pard\intbl\qc\fs18 4 (11.4%) \cell -\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 4 (11.8%) \cell +\pard\intbl\qc\fs18 2 (5.7%) \cell +\pard\intbl\qc\fs18 6 (8.7%) \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsfecg03/tsfecg03.rtf b/tests/testthat/_snaps/tsfecg03/tsfecg03.rtf old mode 100755 new mode 100644 index 4aa216e6..9ba3619e --- a/tests/testthat/_snaps/tsfecg03/tsfecg03.rtf +++ b/tests/testthat/_snaps/tsfecg03/tsfecg03.rtf @@ -3,58 +3,68 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG03:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2828 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7069 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2863 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7608 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr QTc Interval \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li270\fi0 Criteria, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Criteria, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcB Interval, Aggregate (msec) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcB Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -63,70 +73,82 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 56 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?30 \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 29 (54.7%) \cell -\pard\intbl\qc\fs18 37 (66.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8804?30 \cell +\pard\intbl\qc\fs18 25 (53.2%) \cell +\pard\intbl\qc\fs18 29 (56.9%) \cell +\pard\intbl\qc\fs18 54 (55.1%) \cell +\pard\intbl\qc\fs18 43 (70.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >30 to \u8804?60 \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 2 (3.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 >30 to \u8804?60 \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (6.1%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >60 \cell -\pard\intbl\qc\fs18 18 (34.0%) \cell -\pard\intbl\qc\fs18 21 (39.6%) \cell -\pard\intbl\qc\fs18 17 (30.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 >60 \cell +\pard\intbl\qc\fs18 20 (42.6%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 38 (38.8%) \cell +\pard\intbl\qc\fs18 15 (24.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcF Interval, Aggregate (msec) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcF Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -135,73 +157,85 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 56 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?30 \cell -\pard\intbl\qc\fs18 31 (58.5%) \cell -\pard\intbl\qc\fs18 25 (47.2%) \cell -\pard\intbl\qc\fs18 28 (50.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8804?30 \cell +\pard\intbl\qc\fs18 28 (59.6%) \cell +\pard\intbl\qc\fs18 29 (56.9%) \cell +\pard\intbl\qc\fs18 57 (58.2%) \cell +\pard\intbl\qc\fs18 37 (60.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >30 to \u8804?60 \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 8 (14.3%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 >30 to \u8804?60 \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (7.1%) \cell +\pard\intbl\qc\fs18 7 (11.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >60 \cell -\pard\intbl\qc\fs18 18 (34.0%) \cell -\pard\intbl\qc\fs18 25 (47.2%) \cell -\pard\intbl\qc\fs18 20 (35.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 >60 \cell +\pard\intbl\qc\fs18 16 (34.0%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 34 (34.7%) \cell +\pard\intbl\qc\fs18 17 (27.9%) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsfecg04/tsfecg04.rtf b/tests/testthat/_snaps/tsfecg04/tsfecg04.rtf old mode 100755 new mode 100644 index 6587c9b5..56dae66f --- a/tests/testthat/_snaps/tsfecg04/tsfecg04.rtf +++ b/tests/testthat/_snaps/tsfecg04/tsfecg04.rtf @@ -3,12 +3,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2855 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3837 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4907 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5978 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8119 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4065 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5302 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6185 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7952 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG04:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -21,13 +21,13 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2855 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3837 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4907 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5978 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8119 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr QTc Interval \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2828 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4065 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5302 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6185 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7069 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7952 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell @@ -39,13 +39,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4907 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5978 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7048 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8119 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Treatment Group \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5302 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6185 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7952 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr QTc Interval \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Baseline Corrected QT Interval \cell \pard\intbl\qc\fs18 \keepn\trhdr Baseline Corrected QT Interval \cell @@ -57,13 +57,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3837 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4907 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5978 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7048 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8119 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Criteria, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4065 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5302 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6185 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7952 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Treatment Group \cell \pard\intbl\qc\fs18 \keepn\trhdr N \cell \pard\intbl\qc\fs18 \keepn\trhdr \u8804?450 \cell \pard\intbl\qc\fs18 \keepn\trhdr >450 to \u8804?480 \cell @@ -75,14 +75,14 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -93,14 +93,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -111,14 +111,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 64 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -129,12 +129,12 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -147,13 +147,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcB Interval, Aggregate (msec) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcB Interval, Aggregate (ms) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -165,14 +165,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -183,13 +183,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum Corrected QT Interval \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum corrected QT interval, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -201,102 +201,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 31 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 27 \cell \pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 33 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >450 to \u8804?480 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >480 to \u8804?500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 4 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Total \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 37 \cell \pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 47 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -309,14 +309,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -327,13 +327,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum Corrected QT Interval \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum corrected QT interval, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -345,102 +345,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 31 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 27 \cell \pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 37 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >450 to \u8804?480 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >480 to \u8804?500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 3 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 42 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 37 \cell \pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 51 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -453,14 +453,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Placebo \cell -\pard\intbl\qc\fs18 56 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -471,13 +471,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum Corrected QT Interval \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum corrected QT interval, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -489,71 +489,71 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 40 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >450 to \u8804?480 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >480 to \u8804?500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 3 \cell \row @@ -561,30 +561,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 44 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 56 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 61 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -597,13 +597,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcF Interval, Aggregate (msec) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 QTcF Interval, Aggregate (ms) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -615,14 +615,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -633,13 +633,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum Corrected QT Interval \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum corrected QT interval, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -651,102 +651,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 39 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >450 to \u8804?480 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 3 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >480 to \u8804?500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 6 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 4 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 44 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 47 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -759,14 +759,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -777,13 +777,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum Corrected QT Interval \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum corrected QT interval, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -795,102 +795,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 34 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 35 \cell \pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 43 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >450 to \u8804?480 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 4 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >480 to \u8804?500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 45 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 51 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -903,14 +903,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Placebo \cell -\pard\intbl\qc\fs18 56 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -921,13 +921,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum Corrected QT Interval \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Maximum corrected QT interval, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -939,102 +939,102 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 \u8804?450 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 29 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8804?450 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 7 \cell \pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >450 to \u8804?480 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >450 to \u8804?480 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >480 to \u8804?500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >480 to \u8804?500 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 2 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >500 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >500 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2855 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3837 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4907 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5978 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7048 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8119 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 40 \cell -\pard\intbl\qc\fs18 8 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4065 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5302 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6185 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7952 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 61 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2855 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3837 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4907 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5978 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7048 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8119 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4065 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5302 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6185 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7952 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -1047,12 +1047,12 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2855 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3837 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4907 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5978 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7048 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8119 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4065 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5302 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6185 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7952 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfecg05/tsfecg05.rtf b/tests/testthat/_snaps/tsfecg05/tsfecg05.rtf old mode 100755 new mode 100644 index 32360322..92c4410b --- a/tests/testthat/_snaps/tsfecg05/tsfecg05.rtf +++ b/tests/testthat/_snaps/tsfecg05/tsfecg05.rtf @@ -3,130 +3,222 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2849 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4962 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7076 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2872 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4380 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6031 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7682 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG05:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2849 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4962 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7076 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2872 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4380 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6031 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7682 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Criteria, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ECG Mean Heart Rate (beats/min) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 On-treatment \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 \cell +\pard\intbl\qc\fs18 21 (31.8%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 44 (37.6%) \cell +\pard\intbl\qc\fs18 28 (45.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >100 \cell -\pard\intbl\qc\fs18 53 (100.0%) \cell -\pard\intbl\qc\fs18 67 (100.0%) \cell -\pard\intbl\qc\fs18 57 (100.0%) \cell +\pard\intbl\qc\fs18 62 (93.9%) \cell +\pard\intbl\qc\fs18 51 (100.0%) \cell +\pard\intbl\qc\fs18 113 (96.6%) \cell +\pard\intbl\qc\fs18 61 (98.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 \cell -\pard\intbl\qc\fs18 25 (100.0%) \cell -\pard\intbl\qc\fs18 22 (100.0%) \cell -\pard\intbl\qc\fs18 24 (100.0%) \cell +\pard\intbl\qc\fs18 7 (10.6%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 15 (12.8%) \cell +\pard\intbl\qc\fs18 8 (12.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >100 \cell +\pard\intbl\qc\fs18 54 (81.8%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 89 (76.1%) \cell +\pard\intbl\qc\fs18 48 (77.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -135,58 +227,138 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 10 (10.2%) \cell +\pard\intbl\qc\fs18 4 (6.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >100 \cell -\pard\intbl\qc\fs18 36 (100.0%) \cell -\pard\intbl\qc\fs18 57 (100.0%) \cell -\pard\intbl\qc\fs18 45 (100.0%) \cell +\pard\intbl\qc\fs18 39 (83.0%) \cell +\pard\intbl\qc\fs18 42 (82.4%) \cell +\pard\intbl\qc\fs18 81 (82.7%) \cell +\pard\intbl\qc\fs18 49 (80.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 88 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 \cell -\pard\intbl\qc\fs18 11 (100.0%) \cell -\pard\intbl\qc\fs18 6 (100.0%) \cell -\pard\intbl\qc\fs18 8 (100.0%) \cell +\pard\intbl\qc\fs18 4 (9.5%) \cell +\pard\intbl\qc\fs18 5 (10.9%) \cell +\pard\intbl\qc\fs18 9 (10.2%) \cell +\pard\intbl\qc\fs18 9 (16.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >100 \cell +\pard\intbl\qc\fs18 31 (73.8%) \cell +\pard\intbl\qc\fs18 37 (80.4%) \cell +\pard\intbl\qc\fs18 68 (77.3%) \cell +\pard\intbl\qc\fs18 45 (81.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -195,130 +367,502 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 7 (9.2%) \cell +\pard\intbl\qc\fs18 4 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >100 \cell +\pard\intbl\qc\fs18 35 (92.1%) \cell +\pard\intbl\qc\fs18 29 (76.3%) \cell +\pard\intbl\qc\fs18 64 (84.2%) \cell +\pard\intbl\qc\fs18 44 (84.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 \cell +\pard\intbl\qc\fs18 2 (6.1%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (8.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >100 \cell +\pard\intbl\qc\fs18 26 (78.8%) \cell +\pard\intbl\qc\fs18 30 (88.2%) \cell +\pard\intbl\qc\fs18 56 (83.6%) \cell +\pard\intbl\qc\fs18 41 (85.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 26 \cell \pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >100 \cell -\pard\intbl\qc\fs18 42 (100.0%) \cell -\pard\intbl\qc\fs18 43 (100.0%) \cell -\pard\intbl\qc\fs18 45 (100.0%) \cell +\pard\intbl\qc\fs18 22 (81.5%) \cell +\pard\intbl\qc\fs18 23 (88.5%) \cell +\pard\intbl\qc\fs18 45 (84.9%) \cell +\pard\intbl\qc\fs18 43 (89.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 \cell -\pard\intbl\qc\fs18 7 (100.0%) \cell -\pard\intbl\qc\fs18 7 (100.0%) \cell -\pard\intbl\qc\fs18 3 (100.0%) \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 2 (9.1%) \cell +\pard\intbl\qc\fs18 4 (9.5%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >100 \cell +\pard\intbl\qc\fs18 17 (85.0%) \cell +\pard\intbl\qc\fs18 18 (81.8%) \cell +\pard\intbl\qc\fs18 35 (83.3%) \cell +\pard\intbl\qc\fs18 39 (83.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (msec) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 41 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (9.5%) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >100 \cell +\pard\intbl\qc\fs18 18 (94.7%) \cell +\pard\intbl\qc\fs18 17 (81.0%) \cell +\pard\intbl\qc\fs18 35 (87.5%) \cell +\pard\intbl\qc\fs18 32 (78.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 PR Interval, Aggregate (ms) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 On-treatment \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <120 \cell +\pard\intbl\qc\fs18 36 (54.5%) \cell +\pard\intbl\qc\fs18 36 (70.6%) \cell +\pard\intbl\qc\fs18 72 (61.5%) \cell +\pard\intbl\qc\fs18 45 (72.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >200 \cell -\pard\intbl\qc\fs18 53 (100.0%) \cell -\pard\intbl\qc\fs18 67 (100.0%) \cell -\pard\intbl\qc\fs18 54 (100.0%) \cell +\pard\intbl\qc\fs18 61 (92.4%) \cell +\pard\intbl\qc\fs18 51 (100.0%) \cell +\pard\intbl\qc\fs18 112 (95.7%) \cell +\pard\intbl\qc\fs18 59 (95.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <120 \cell -\pard\intbl\qc\fs18 34 (100.0%) \cell -\pard\intbl\qc\fs18 43 (100.0%) \cell -\pard\intbl\qc\fs18 47 (100.0%) \cell +\pard\intbl\qc\fs18 15 (22.7%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 22 (18.8%) \cell +\pard\intbl\qc\fs18 14 (22.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >200 \cell +\pard\intbl\qc\fs18 41 (62.1%) \cell +\pard\intbl\qc\fs18 37 (72.5%) \cell +\pard\intbl\qc\fs18 78 (66.7%) \cell +\pard\intbl\qc\fs18 40 (64.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -327,58 +871,138 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <120 \cell +\pard\intbl\qc\fs18 7 (14.9%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 17 (17.3%) \cell +\pard\intbl\qc\fs18 13 (21.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >200 \cell -\pard\intbl\qc\fs18 39 (100.0%) \cell -\pard\intbl\qc\fs18 46 (100.0%) \cell -\pard\intbl\qc\fs18 35 (100.0%) \cell +\pard\intbl\qc\fs18 34 (72.3%) \cell +\pard\intbl\qc\fs18 31 (60.8%) \cell +\pard\intbl\qc\fs18 65 (66.3%) \cell +\pard\intbl\qc\fs18 38 (62.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 88 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <120 \cell -\pard\intbl\qc\fs18 6 (100.0%) \cell -\pard\intbl\qc\fs18 17 (100.0%) \cell -\pard\intbl\qc\fs18 13 (100.0%) \cell +\pard\intbl\qc\fs18 13 (31.0%) \cell +\pard\intbl\qc\fs18 11 (23.9%) \cell +\pard\intbl\qc\fs18 24 (27.3%) \cell +\pard\intbl\qc\fs18 13 (23.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >200 \cell +\pard\intbl\qc\fs18 25 (59.5%) \cell +\pard\intbl\qc\fs18 29 (63.0%) \cell +\pard\intbl\qc\fs18 54 (61.4%) \cell +\pard\intbl\qc\fs18 35 (63.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 9 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -387,61 +1011,351 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <120 \cell +\pard\intbl\qc\fs18 7 (18.4%) \cell +\pard\intbl\qc\fs18 9 (23.7%) \cell +\pard\intbl\qc\fs18 16 (21.1%) \cell +\pard\intbl\qc\fs18 12 (23.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >200 \cell +\pard\intbl\qc\fs18 24 (63.2%) \cell +\pard\intbl\qc\fs18 21 (55.3%) \cell +\pard\intbl\qc\fs18 45 (59.2%) \cell +\pard\intbl\qc\fs18 35 (67.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <120 \cell +\pard\intbl\qc\fs18 3 (9.1%) \cell +\pard\intbl\qc\fs18 10 (29.4%) \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 14 (29.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >200 \cell +\pard\intbl\qc\fs18 24 (72.7%) \cell +\pard\intbl\qc\fs18 19 (55.9%) \cell +\pard\intbl\qc\fs18 43 (64.2%) \cell +\pard\intbl\qc\fs18 30 (62.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 26 \cell \pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <120 \cell +\pard\intbl\qc\fs18 6 (22.2%) \cell +\pard\intbl\qc\fs18 4 (15.4%) \cell +\pard\intbl\qc\fs18 10 (18.9%) \cell +\pard\intbl\qc\fs18 11 (22.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >200 \cell -\pard\intbl\qc\fs18 34 (100.0%) \cell -\pard\intbl\qc\fs18 33 (100.0%) \cell -\pard\intbl\qc\fs18 33 (100.0%) \cell +\pard\intbl\qc\fs18 18 (66.7%) \cell +\pard\intbl\qc\fs18 18 (69.2%) \cell +\pard\intbl\qc\fs18 36 (67.9%) \cell +\pard\intbl\qc\fs18 34 (70.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4962 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7076 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <120 \cell -\pard\intbl\qc\fs18 9 (100.0%) \cell -\pard\intbl\qc\fs18 10 (100.0%) \cell -\pard\intbl\qc\fs18 14 (100.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2849 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4962 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7076 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <120 \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 6 (27.3%) \cell +\pard\intbl\qc\fs18 8 (19.0%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >200 \cell +\pard\intbl\qc\fs18 15 (75.0%) \cell +\pard\intbl\qc\fs18 14 (63.6%) \cell +\pard\intbl\qc\fs18 29 (69.0%) \cell +\pard\intbl\qc\fs18 35 (74.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <120 \cell +\pard\intbl\qc\fs18 4 (21.1%) \cell +\pard\intbl\qc\fs18 6 (28.6%) \cell +\pard\intbl\qc\fs18 10 (25.0%) \cell +\pard\intbl\qc\fs18 13 (31.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2872 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4380 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6031 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7682 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >200 \cell +\pard\intbl\qc\fs18 14 (73.7%) \cell +\pard\intbl\qc\fs18 12 (57.1%) \cell +\pard\intbl\qc\fs18 26 (65.0%) \cell +\pard\intbl\qc\fs18 25 (61.0%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2872 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4380 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6031 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7682 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4962 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7076 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2872 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4380 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6031 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7682 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsfecg06/tsfecg06.rtf b/tests/testthat/_snaps/tsfecg06/tsfecg06.rtf new file mode 100644 index 00000000..f08feb6b --- /dev/null +++ b/tests/testthat/_snaps/tsfecg06/tsfecg06.rtf @@ -0,0 +1,830 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFECG06:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10232 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Study Visit \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Overall Interpretation, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, CS \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 31 (26.3%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, NCS \cell +\pard\intbl\qc\fs18 22 (32.8%) \cell +\pard\intbl\qc\fs18 19 (37.3%) \cell +\pard\intbl\qc\fs18 41 (34.7%) \cell +\pard\intbl\qc\fs18 27 (42.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Normal \cell +\pard\intbl\qc\fs18 27 (40.3%) \cell +\pard\intbl\qc\fs18 19 (37.3%) \cell +\pard\intbl\qc\fs18 46 (39.0%) \cell +\pard\intbl\qc\fs18 24 (37.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Month 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, CS \cell +\pard\intbl\qc\fs18 26 (39.4%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 49 (41.9%) \cell +\pard\intbl\qc\fs18 23 (37.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, NCS \cell +\pard\intbl\qc\fs18 22 (33.3%) \cell +\pard\intbl\qc\fs18 15 (29.4%) \cell +\pard\intbl\qc\fs18 37 (31.6%) \cell +\pard\intbl\qc\fs18 18 (29.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Normal \cell +\pard\intbl\qc\fs18 18 (27.3%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 31 (26.5%) \cell +\pard\intbl\qc\fs18 21 (33.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Month 3 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, CS \cell +\pard\intbl\qc\fs18 19 (40.4%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 30 (30.6%) \cell +\pard\intbl\qc\fs18 28 (45.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, NCS \cell +\pard\intbl\qc\fs18 14 (29.8%) \cell +\pard\intbl\qc\fs18 20 (39.2%) \cell +\pard\intbl\qc\fs18 34 (34.7%) \cell +\pard\intbl\qc\fs18 15 (24.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Normal \cell +\pard\intbl\qc\fs18 14 (29.8%) \cell +\pard\intbl\qc\fs18 20 (39.2%) \cell +\pard\intbl\qc\fs18 34 (34.7%) \cell +\pard\intbl\qc\fs18 18 (29.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Month 6 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, CS \cell +\pard\intbl\qc\fs18 14 (33.3%) \cell +\pard\intbl\qc\fs18 15 (31.9%) \cell +\pard\intbl\qc\fs18 29 (32.6%) \cell +\pard\intbl\qc\fs18 21 (38.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, NCS \cell +\pard\intbl\qc\fs18 15 (35.7%) \cell +\pard\intbl\qc\fs18 18 (38.3%) \cell +\pard\intbl\qc\fs18 33 (37.1%) \cell +\pard\intbl\qc\fs18 17 (30.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Normal \cell +\pard\intbl\qc\fs18 13 (31.0%) \cell +\pard\intbl\qc\fs18 14 (29.8%) \cell +\pard\intbl\qc\fs18 27 (30.3%) \cell +\pard\intbl\qc\fs18 17 (30.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Month 9 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, CS \cell +\pard\intbl\qc\fs18 14 (35.9%) \cell +\pard\intbl\qc\fs18 12 (30.8%) \cell +\pard\intbl\qc\fs18 26 (33.3%) \cell +\pard\intbl\qc\fs18 21 (40.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, NCS \cell +\pard\intbl\qc\fs18 15 (38.5%) \cell +\pard\intbl\qc\fs18 16 (41.0%) \cell +\pard\intbl\qc\fs18 31 (39.7%) \cell +\pard\intbl\qc\fs18 18 (34.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Normal \cell +\pard\intbl\qc\fs18 10 (25.6%) \cell +\pard\intbl\qc\fs18 11 (28.2%) \cell +\pard\intbl\qc\fs18 21 (26.9%) \cell +\pard\intbl\qc\fs18 13 (25.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Month 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, CS \cell +\pard\intbl\qc\fs18 12 (35.3%) \cell +\pard\intbl\qc\fs18 12 (34.3%) \cell +\pard\intbl\qc\fs18 24 (34.8%) \cell +\pard\intbl\qc\fs18 22 (45.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, NCS \cell +\pard\intbl\qc\fs18 18 (52.9%) \cell +\pard\intbl\qc\fs18 12 (34.3%) \cell +\pard\intbl\qc\fs18 30 (43.5%) \cell +\pard\intbl\qc\fs18 13 (27.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Normal \cell +\pard\intbl\qc\fs18 4 (11.8%) \cell +\pard\intbl\qc\fs18 11 (31.4%) \cell +\pard\intbl\qc\fs18 15 (21.7%) \cell +\pard\intbl\qc\fs18 13 (27.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Month 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, CS \cell +\pard\intbl\qc\fs18 12 (42.9%) \cell +\pard\intbl\qc\fs18 8 (29.6%) \cell +\pard\intbl\qc\fs18 20 (36.4%) \cell +\pard\intbl\qc\fs18 15 (31.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, NCS \cell +\pard\intbl\qc\fs18 11 (39.3%) \cell +\pard\intbl\qc\fs18 12 (44.4%) \cell +\pard\intbl\qc\fs18 23 (41.8%) \cell +\pard\intbl\qc\fs18 15 (31.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Normal \cell +\pard\intbl\qc\fs18 5 (17.9%) \cell +\pard\intbl\qc\fs18 7 (25.9%) \cell +\pard\intbl\qc\fs18 12 (21.8%) \cell +\pard\intbl\qc\fs18 18 (37.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Month 18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, CS \cell +\pard\intbl\qc\fs18 9 (42.9%) \cell +\pard\intbl\qc\fs18 9 (40.9%) \cell +\pard\intbl\qc\fs18 18 (41.9%) \cell +\pard\intbl\qc\fs18 14 (29.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, NCS \cell +\pard\intbl\qc\fs18 5 (23.8%) \cell +\pard\intbl\qc\fs18 5 (22.7%) \cell +\pard\intbl\qc\fs18 10 (23.3%) \cell +\pard\intbl\qc\fs18 19 (40.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Normal \cell +\pard\intbl\qc\fs18 7 (33.3%) \cell +\pard\intbl\qc\fs18 8 (36.4%) \cell +\pard\intbl\qc\fs18 15 (34.9%) \cell +\pard\intbl\qc\fs18 14 (29.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Month 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, CS \cell +\pard\intbl\qc\fs18 5 (25.0%) \cell +\pard\intbl\qc\fs18 6 (28.6%) \cell +\pard\intbl\qc\fs18 11 (26.8%) \cell +\pard\intbl\qc\fs18 11 (26.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Abnormal, NCS \cell +\pard\intbl\qc\fs18 5 (25.0%) \cell +\pard\intbl\qc\fs18 4 (19.0%) \cell +\pard\intbl\qc\fs18 9 (22.0%) \cell +\pard\intbl\qc\fs18 17 (41.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5292 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10232 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Normal \cell +\pard\intbl\qc\fs18 10 (50.0%) \cell +\pard\intbl\qc\fs18 11 (52.4%) \cell +\pard\intbl\qc\fs18 21 (51.2%) \cell +\pard\intbl\qc\fs18 13 (31.7%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5292 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7762 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10232 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab01apart1/tsflab01apart1of3.rtf b/tests/testthat/_snaps/tsflab01apart1/tsflab01apart1of3.rtf deleted file mode 100644 index c6dae31b..00000000 --- a/tests/testthat/_snaps/tsflab01apart1/tsflab01apart1of3.rtf +++ /dev/null @@ -1,988 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2832 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5178 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8899 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB01apart1of3:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2832 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5178 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8899 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5178 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8899 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2832 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5178 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8899 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 2.2923 (2.2328, 2.3517) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 3/8 (37.5%) \cell -\pard\intbl\qc\fs18 2.2122 (2.0832, 2.3412) \cell -\pard\intbl\qc\fs18 -0.0333 (-0.1764, 0.1099) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 3/8 (37.5%) \cell -\pard\intbl\qc\fs18 2.2455 (1.9753, 2.5156) \cell -\pard\intbl\qc\fs18 -0.1331 (-0.3836, 0.1174) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 2/8 (25.0%) \cell -\pard\intbl\qc\fs18 2.1956 (0.6099, 3.7813) \cell -\pard\intbl\qc\fs18 -0.1372 (-0.9298, 0.6553) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 7/8 (87.5%) \cell -\pard\intbl\qc\fs18 4.8690 (4.3508, 5.3873) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 4/8 (50.0%) \cell -\pard\intbl\qc\fs18 7.6742 (-1.9714, 17.3199) \cell -\pard\intbl\qc\fs18 1.2490 (-2.9572, 5.4552) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 3/8 (37.5%) \cell -\pard\intbl\qc\fs18 5.3475 (4.1909, 6.5040) \cell -\pard\intbl\qc\fs18 0.2776 (-0.5612, 1.1163) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 4/8 (50.0%) \cell -\pard\intbl\qc\fs18 5.6759 (3.7755, 7.5763) \cell -\pard\intbl\qc\fs18 0.6384 (-0.8632, 2.1400) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 4.24 (4.05, 4.43) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 5/8 (62.5%) \cell -\pard\intbl\qc\fs18 4.12 (3.80, 4.44) \cell -\pard\intbl\qc\fs18 -0.14 (-0.40, 0.12) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 6/8 (75.0%) \cell -\pard\intbl\qc\fs18 4.00 (3.64, 4.36) \cell -\pard\intbl\qc\fs18 -0.22 (-0.43, -0.00) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 6/8 (75.0%) \cell -\pard\intbl\qc\fs18 3.90 (3.72, 4.08) \cell -\pard\intbl\qc\fs18 -0.32 (-0.51, -0.12) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 138.8 (136.3, 141.2) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 3/8 (37.5%) \cell -\pard\intbl\qc\fs18 137.3 (123.7, 151.0) \cell -\pard\intbl\qc\fs18 -2.3 (-7.5, 2.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 4/8 (50.0%) \cell -\pard\intbl\qc\fs18 138.5 (133.7, 143.3) \cell -\pard\intbl\qc\fs18 -2.0 (-4.6, 0.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 4/8 (50.0%) \cell -\pard\intbl\qc\fs18 137.8 (134.2, 141.3) \cell -\pard\intbl\qc\fs18 -1.8 (-4.8, 1.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 2.3203 (2.2609, 2.3798) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 8/16 (50.0%) \cell -\pard\intbl\qc\fs18 2.3484 (2.2869, 2.4099) \cell -\pard\intbl\qc\fs18 0.0218 (-0.0473, 0.0910) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 7/16 (43.8%) \cell -\pard\intbl\qc\fs18 2.3453 (2.2006, 2.4900) \cell -\pard\intbl\qc\fs18 0.0214 (-0.0623, 0.1050) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 9/15 (60.0%) \cell -\pard\intbl\qc\fs18 2.2399 (2.1903, 2.2895) \cell -\pard\intbl\qc\fs18 -0.0582 (-0.1196, 0.0032) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 5.1590 (4.6692, 5.6488) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 7/16 (43.8%) \cell -\pard\intbl\qc\fs18 4.8135 (3.9354, 5.6916) \cell -\pard\intbl\qc\fs18 -0.0317 (-0.9213, 0.8579) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 10/16 (62.5%) \cell -\pard\intbl\qc\fs18 6.3948 (4.4308, 8.3587) \cell -\pard\intbl\qc\fs18 0.9992 (-0.3407, 2.3390) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 7/15 (46.7%) \cell -\pard\intbl\qc\fs18 5.3131 (3.9917, 6.6346) \cell -\pard\intbl\qc\fs18 0.4361 (-1.3230, 2.1953) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 15/16 (93.8%) \cell -\pard\intbl\qc\fs18 4.43 (4.24, 4.62) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 9/16 (56.2%) \cell -\pard\intbl\qc\fs18 4.57 (4.25, 4.88) \cell -\pard\intbl\qc\fs18 0.26 (-0.08, 0.59) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 8/16 (50.0%) \cell -\pard\intbl\qc\fs18 4.26 (4.03, 4.50) \cell -\pard\intbl\qc\fs18 -0.36 (-0.64, -0.08) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 8/15 (53.3%) \cell -\pard\intbl\qc\fs18 4.16 (4.04, 4.29) \cell -\pard\intbl\qc\fs18 -0.41 (-0.70, -0.13) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 15/16 (93.8%) \cell -\pard\intbl\qc\fs18 140.3 (138.9, 141.7) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 10/16 (62.5%) \cell -\pard\intbl\qc\fs18 138.8 (137.5, 140.1) \cell -\pard\intbl\qc\fs18 -1.9 (-4.1, 0.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 8/16 (50.0%) \cell -\pard\intbl\qc\fs18 139.2 (137.9, 140.6) \cell -\pard\intbl\qc\fs18 -1.5 (-3.7, 0.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 2/15 (13.3%) \cell -\pard\intbl\qc\fs18 138.5 (81.3, 195.7) \cell -\pard\intbl\qc\fs18 -1.5 (-71.4, 68.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 28/29 (96.6%) \cell -\pard\intbl\qc\fs18 2.2918 (2.2512, 2.3324) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 18/29 (62.1%) \cell -\pard\intbl\qc\fs18 2.2732 (2.2059, 2.3405) \cell -\pard\intbl\qc\fs18 -0.0236 (-0.0790, 0.0318) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 11/29 (37.9%) \cell -\pard\intbl\qc\fs18 2.2773 (2.2206, 2.3339) \cell -\pard\intbl\qc\fs18 0.0045 (-0.0722, 0.0813) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 13/27 (48.1%) \cell -\pard\intbl\qc\fs18 2.2935 (2.2520, 2.3350) \cell -\pard\intbl\qc\fs18 -0.0038 (-0.0737, 0.0660) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 27/29 (93.1%) \cell -\pard\intbl\qc\fs18 5.4852 (4.9345, 6.0359) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 16/29 (55.2%) \cell -\pard\intbl\qc\fs18 7.3308 (4.8598, 9.8018) \cell -\pard\intbl\qc\fs18 1.4988 (-0.3368, 3.3343) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 14/29 (48.3%) \cell -\pard\intbl\qc\fs18 6.3678 (4.9685, 7.7671) \cell -\pard\intbl\qc\fs18 0.8009 (0.1175, 1.4844) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 12/27 (44.4%) \cell -\pard\intbl\qc\fs18 7.6743 (4.1117, 11.2368) \cell -\pard\intbl\qc\fs18 1.4756 (-1.3474, 4.2987) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 28/29 (96.6%) \cell -\pard\intbl\qc\fs18 4.19 (4.05, 4.34) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 15/29 (51.7%) \cell -\pard\intbl\qc\fs18 4.24 (4.03, 4.45) \cell -\pard\intbl\qc\fs18 0.17 (-0.02, 0.36) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 11/29 (37.9%) \cell -\pard\intbl\qc\fs18 4.32 (4.02, 4.61) \cell -\pard\intbl\qc\fs18 -0.13 (-0.50, 0.25) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 10/27 (37.0%) \cell -\pard\intbl\qc\fs18 4.21 (3.91, 4.51) \cell -\pard\intbl\qc\fs18 0.05 (-0.24, 0.34) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 140.0 (139.1, 141.0) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 9/29 (31.0%) \cell -\pard\intbl\qc\fs18 139.0 (137.0, 141.0) \cell -\pard\intbl\qc\fs18 -0.2 (-3.2, 2.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 14/29 (48.3%) \cell -\pard\intbl\qc\fs18 140.0 (138.3, 141.7) \cell -\pard\intbl\qc\fs18 0.8 (-1.1, 2.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 20/27 (74.1%) \cell -\pard\intbl\qc\fs18 141.2 (140.1, 142.4) \cell -\pard\intbl\qc\fs18 1.6 (0.4, 2.7) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2832 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5178 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8899 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab01apart2/tsflab01apart2of3.rtf b/tests/testthat/_snaps/tsflab01apart2/tsflab01apart2of3.rtf deleted file mode 100755 index 8048cca8..00000000 --- a/tests/testthat/_snaps/tsflab01apart2/tsflab01apart2of3.rtf +++ /dev/null @@ -1,988 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2832 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5178 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8899 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB01apart2of3:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2832 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5178 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8899 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5178 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8899 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2832 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5178 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8899 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 2.2654 (2.1370, 2.3939) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 3/5 (60.0%) \cell -\pard\intbl\qc\fs18 2.2954 (2.0251, 2.5657) \cell -\pard\intbl\qc\fs18 0.0499 (-0.1980, 0.2978) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 1/5 (20.0%) \cell -\pard\intbl\qc\fs18 2.1956 (NE, NE) \cell -\pard\intbl\qc\fs18 -0.1248 (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 3/3 (100.0%) \cell -\pard\intbl\qc\fs18 2.3203 (2.0363, 2.6044) \cell -\pard\intbl\qc\fs18 0.0333 (-0.1844, 0.2509) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 5.2623 (4.8804, 5.6442) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 2/5 (40.0%) \cell -\pard\intbl\qc\fs18 4.4130 (-4.4032, 13.2293) \cell -\pard\intbl\qc\fs18 -0.6106 (-7.6638, 6.4426) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 3/5 (60.0%) \cell -\pard\intbl\qc\fs18 4.2928 (3.7187, 4.8669) \cell -\pard\intbl\qc\fs18 -0.9252 (-2.2645, 0.4141) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 1/3 (33.3%) \cell -\pard\intbl\qc\fs18 5.8841 (NE, NE) \cell -\pard\intbl\qc\fs18 0.3331 (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 4.12 (3.96, 4.28) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 1/5 (20.0%) \cell -\pard\intbl\qc\fs18 4.20 (NE, NE) \cell -\pard\intbl\qc\fs18 0.20 (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 0/5 \cell -\pard\intbl\qc\fs18 NE (NE, NE) \cell -\pard\intbl\qc\fs18 NE (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 2/3 (66.7%) \cell -\pard\intbl\qc\fs18 3.80 (-5.09, 12.69) \cell -\pard\intbl\qc\fs18 -0.45 (-8.71, 7.81) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 139.6 (137.9, 141.3) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 4/5 (80.0%) \cell -\pard\intbl\qc\fs18 139.2 (135.7, 142.8) \cell -\pard\intbl\qc\fs18 -0.8 (-4.0, 2.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 4/5 (80.0%) \cell -\pard\intbl\qc\fs18 142.0 (138.6, 145.4) \cell -\pard\intbl\qc\fs18 2.8 (-2.5, 8.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 1/3 (33.3%) \cell -\pard\intbl\qc\fs18 141.0 (NE, NE) \cell -\pard\intbl\qc\fs18 0.0 (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 2.2822 (2.2287, 2.3357) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 6/16 (37.5%) \cell -\pard\intbl\qc\fs18 2.2580 (2.1632, 2.3528) \cell -\pard\intbl\qc\fs18 -0.1081 (-0.2531, 0.0369) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 5/10 (50.0%) \cell -\pard\intbl\qc\fs18 2.2555 (2.1718, 2.3392) \cell -\pard\intbl\qc\fs18 0.0100 (-0.0894, 0.1094) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 4/9 (44.4%) \cell -\pard\intbl\qc\fs18 2.2393 (2.0492, 2.4293) \cell -\pard\intbl\qc\fs18 -0.0499 (-0.2183, 0.1185) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 5.2016 (4.6787, 5.7245) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 7/16 (43.8%) \cell -\pard\intbl\qc\fs18 5.0673 (4.4263, 5.7083) \cell -\pard\intbl\qc\fs18 -0.5789 (-1.8506, 0.6928) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 3/10 (30.0%) \cell -\pard\intbl\qc\fs18 6.0691 (2.9847, 9.1535) \cell -\pard\intbl\qc\fs18 0.1850 (-0.4952, 0.8653) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 4/9 (44.4%) \cell -\pard\intbl\qc\fs18 5.4677 (3.7226, 7.2128) \cell -\pard\intbl\qc\fs18 -0.0555 (-1.7652, 1.6542) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 4.43 (4.24, 4.62) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 10/16 (62.5%) \cell -\pard\intbl\qc\fs18 4.17 (3.87, 4.47) \cell -\pard\intbl\qc\fs18 -0.20 (-0.60, 0.20) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 6/10 (60.0%) \cell -\pard\intbl\qc\fs18 4.22 (3.77, 4.66) \cell -\pard\intbl\qc\fs18 -0.13 (-0.49, 0.22) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 3/9 (33.3%) \cell -\pard\intbl\qc\fs18 4.13 (3.37, 4.89) \cell -\pard\intbl\qc\fs18 -0.10 (-1.48, 1.28) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 140.1 (138.7, 141.6) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 8/16 (50.0%) \cell -\pard\intbl\qc\fs18 139.4 (138.4, 140.4) \cell -\pard\intbl\qc\fs18 0.0 (-3.2, 3.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 4/10 (40.0%) \cell -\pard\intbl\qc\fs18 141.5 (138.7, 144.3) \cell -\pard\intbl\qc\fs18 -0.2 (-2.6, 2.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 4/9 (44.4%) \cell -\pard\intbl\qc\fs18 139.8 (135.2, 144.3) \cell -\pard\intbl\qc\fs18 -0.2 (-3.0, 2.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 46/50 (92.0%) \cell -\pard\intbl\qc\fs18 2.3057 (2.2699, 2.3415) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 22/46 (47.8%) \cell -\pard\intbl\qc\fs18 2.3011 (2.2362, 2.3659) \cell -\pard\intbl\qc\fs18 -0.0079 (-0.0561, 0.0403) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 15/37 (40.5%) \cell -\pard\intbl\qc\fs18 2.2954 (2.2424, 2.3484) \cell -\pard\intbl\qc\fs18 -0.0283 (-0.0666, 0.0101) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 18/35 (51.4%) \cell -\pard\intbl\qc\fs18 2.2857 (2.2287, 2.3427) \cell -\pard\intbl\qc\fs18 0.0069 (-0.0332, 0.0470) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 48/50 (96.0%) \cell -\pard\intbl\qc\fs18 5.5001 (5.1602, 5.8400) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 21/46 (45.7%) \cell -\pard\intbl\qc\fs18 5.5959 (4.9945, 6.1974) \cell -\pard\intbl\qc\fs18 0.3516 (-0.2345, 0.9377) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 24/37 (64.9%) \cell -\pard\intbl\qc\fs18 5.4585 (4.9706, 5.9464) \cell -\pard\intbl\qc\fs18 0.0601 (-0.3467, 0.4670) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 16/35 (45.7%) \cell -\pard\intbl\qc\fs18 5.2179 (4.8509, 5.5850) \cell -\pard\intbl\qc\fs18 -0.2984 (-0.8830, 0.2863) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 46/50 (92.0%) \cell -\pard\intbl\qc\fs18 4.31 (4.20, 4.42) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 20/46 (43.5%) \cell -\pard\intbl\qc\fs18 4.30 (4.08, 4.51) \cell -\pard\intbl\qc\fs18 0.02 (-0.18, 0.22) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 18/37 (48.6%) \cell -\pard\intbl\qc\fs18 4.39 (4.14, 4.65) \cell -\pard\intbl\qc\fs18 0.03 (-0.13, 0.19) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 19/35 (54.3%) \cell -\pard\intbl\qc\fs18 4.32 (4.12, 4.52) \cell -\pard\intbl\qc\fs18 0.03 (-0.18, 0.24) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 47/50 (94.0%) \cell -\pard\intbl\qc\fs18 139.7 (138.9, 140.5) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 23/46 (50.0%) \cell -\pard\intbl\qc\fs18 139.7 (138.3, 141.2) \cell -\pard\intbl\qc\fs18 0.8 (-0.6, 2.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 16/37 (43.2%) \cell -\pard\intbl\qc\fs18 140.1 (138.7, 141.5) \cell -\pard\intbl\qc\fs18 0.5 (-0.9, 1.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2832 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5178 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8899 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 15/35 (42.9%) \cell -\pard\intbl\qc\fs18 140.5 (139.3, 141.6) \cell -\pard\intbl\qc\fs18 1.1 (-0.1, 2.3) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2832 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5178 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8899 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2832 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5178 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8899 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab01apart3/tsflab01apart3of3.rtf b/tests/testthat/_snaps/tsflab01apart3/tsflab01apart3of3.rtf deleted file mode 100644 index 9e5be1c5..00000000 --- a/tests/testthat/_snaps/tsflab01apart3/tsflab01apart3of3.rtf +++ /dev/null @@ -1,1316 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4144 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6216 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8378 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10494 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB01apart3of3:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4144 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6216 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8378 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10494 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4144 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6216 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8378 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4144 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6216 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 2.3453 (2.2447, 2.4459) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 3/7 (42.9%) \cell -\pard\intbl\qc\fs18 2.2788 (2.1840, 2.3735) \cell -\pard\intbl\qc\fs18 0.0083 (-0.1477, 0.1643) \cell -\pard\intbl\qc\fs18 -0.0416 (-0.1786, 0.0954) \cell -\pard\intbl\qc\fs18 0.0416 (-0.1622, 0.2454) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 2/7 (28.6%) \cell -\pard\intbl\qc\fs18 2.3578 (2.1996, 2.5159) \cell -\pard\intbl\qc\fs18 -0.0749 (-0.3919, 0.2422) \cell -\pard\intbl\qc\fs18 -0.0582 (-0.2771, 0.1607) \cell -\pard\intbl\qc\fs18 -0.0499 (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 1/5 (20.0%) \cell -\pard\intbl\qc\fs18 2.1956 (NE, NE) \cell -\pard\intbl\qc\fs18 0.0250 (NE, NE) \cell -\pard\intbl\qc\fs18 -0.1622 (NE, NE) \cell -\pard\intbl\qc\fs18 0.0083 (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 4.9800 (4.4337, 5.5264) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 2/7 (28.6%) \cell -\pard\intbl\qc\fs18 6.0228 (-4.9096, 16.9552) \cell -\pard\intbl\qc\fs18 0.7216 (-14.7954, 16.2387) \cell -\pard\intbl\qc\fs18 0.5273 (-4.9711, 6.0258) \cell -\pard\intbl\qc\fs18 -1.3322 (-10.2987, 7.6342) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 1/7 (14.3%) \cell -\pard\intbl\qc\fs18 4.6628 (NE, NE) \cell -\pard\intbl\qc\fs18 -0.2775 (NE, NE) \cell -\pard\intbl\qc\fs18 0.5551 (NE, NE) \cell -\pard\intbl\qc\fs18 -0.6476 (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 2/5 (40.0%) \cell -\pard\intbl\qc\fs18 5.9118 (5.5593, 6.2644) \cell -\pard\intbl\qc\fs18 0.7216 (-5.6263, 7.0695) \cell -\pard\intbl\qc\fs18 -0.0833 (-2.3468, 2.1803) \cell -\pard\intbl\qc\fs18 -0.3886 (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 4.44 (3.86, 5.02) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 6/7 (85.7%) \cell -\pard\intbl\qc\fs18 4.45 (3.89, 5.01) \cell -\pard\intbl\qc\fs18 0.02 (-0.42, 0.45) \cell -\pard\intbl\qc\fs18 -0.16 (-0.61, 0.29) \cell -\pard\intbl\qc\fs18 0.18 (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 6/7 (85.7%) \cell -\pard\intbl\qc\fs18 4.38 (3.88, 4.88) \cell -\pard\intbl\qc\fs18 -0.02 (-0.62, 0.59) \cell -\pard\intbl\qc\fs18 -0.20 (-0.81, 0.41) \cell -\pard\intbl\qc\fs18 NE (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 3/5 (60.0%) \cell -\pard\intbl\qc\fs18 4.23 (2.96, 5.51) \cell -\pard\intbl\qc\fs18 0.00 (-0.25, 0.25) \cell -\pard\intbl\qc\fs18 -0.32 (-0.54, -0.09) \cell -\pard\intbl\qc\fs18 -0.45 (-8.44, 7.54) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 140.4 (137.5, 143.3) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 4/7 (57.1%) \cell -\pard\intbl\qc\fs18 139.8 (137.4, 142.1) \cell -\pard\intbl\qc\fs18 -1.2 (-6.5, 4.0) \cell -\pard\intbl\qc\fs18 -1.1 (-6.4, 4.2) \cell -\pard\intbl\qc\fs18 0.5 (-4.5, 5.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 4/7 (57.1%) \cell -\pard\intbl\qc\fs18 138.2 (135.0, 141.5) \cell -\pard\intbl\qc\fs18 -2.2 (-8.7, 4.2) \cell -\pard\intbl\qc\fs18 0.2 (-5.8, 6.3) \cell -\pard\intbl\qc\fs18 5.0 (-1.4, 11.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 4/5 (80.0%) \cell -\pard\intbl\qc\fs18 140.5 (135.6, 145.4) \cell -\pard\intbl\qc\fs18 0.2 (-4.3, 4.8) \cell -\pard\intbl\qc\fs18 -2.0 (-6.4, 2.4) \cell -\pard\intbl\qc\fs18 -0.2 (NE, NE) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 17/19 (89.5%) \cell -\pard\intbl\qc\fs18 2.2866 (2.2463, 2.3269) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 13/19 (68.4%) \cell -\pard\intbl\qc\fs18 2.2685 (2.2007, 2.3364) \cell -\pard\intbl\qc\fs18 -0.0154 (-0.0729, 0.0422) \cell -\pard\intbl\qc\fs18 0.0372 (-0.0461, 0.1205) \cell -\pard\intbl\qc\fs18 -0.0928 (-0.2389, 0.0534) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 11/19 (57.9%) \cell -\pard\intbl\qc\fs18 2.2432 (2.1973, 2.2891) \cell -\pard\intbl\qc\fs18 -0.0227 (-0.0727, 0.0273) \cell -\pard\intbl\qc\fs18 0.0441 (-0.0459, 0.1340) \cell -\pard\intbl\qc\fs18 0.0327 (-0.0664, 0.1317) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 7/19 (36.8%) \cell -\pard\intbl\qc\fs18 2.2776 (2.1755, 2.3796) \cell -\pard\intbl\qc\fs18 0.0036 (-0.1450, 0.1522) \cell -\pard\intbl\qc\fs18 -0.0618 (-0.2137, 0.0902) \cell -\pard\intbl\qc\fs18 -0.0535 (-0.2369, 0.1300) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 18/19 (94.7%) \cell -\pard\intbl\qc\fs18 5.1008 (4.8030, 5.3985) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 13/19 (68.4%) \cell -\pard\intbl\qc\fs18 5.3204 (4.3573, 6.2835) \cell -\pard\intbl\qc\fs18 0.1751 (-0.6520, 1.0022) \cell -\pard\intbl\qc\fs18 -0.2068 (-1.3187, 0.9051) \cell -\pard\intbl\qc\fs18 -0.7540 (-2.1518, 0.6439) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 9/19 (47.4%) \cell -\pard\intbl\qc\fs18 5.7977 (4.6869, 6.9086) \cell -\pard\intbl\qc\fs18 0.4071 (-0.8660, 1.6802) \cell -\pard\intbl\qc\fs18 0.5921 (-1.1162, 2.3004) \cell -\pard\intbl\qc\fs18 -0.2220 (-1.5185, 1.0744) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 5/19 (26.3%) \cell -\pard\intbl\qc\fs18 4.6961 (4.2532, 5.1391) \cell -\pard\intbl\qc\fs18 -0.2442 (-0.6680, 0.1795) \cell -\pard\intbl\qc\fs18 0.6804 (-1.0830, 2.4438) \cell -\pard\intbl\qc\fs18 0.1887 (-1.4562, 1.8337) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 4.16 (3.95, 4.36) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 8/19 (42.1%) \cell -\pard\intbl\qc\fs18 4.11 (3.83, 4.39) \cell -\pard\intbl\qc\fs18 -0.03 (-0.37, 0.32) \cell -\pard\intbl\qc\fs18 0.28 (-0.16, 0.72) \cell -\pard\intbl\qc\fs18 -0.17 (-0.66, 0.31) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 9/19 (47.4%) \cell -\pard\intbl\qc\fs18 3.93 (3.78, 4.09) \cell -\pard\intbl\qc\fs18 -0.20 (-0.50, 0.10) \cell -\pard\intbl\qc\fs18 -0.16 (-0.53, 0.21) \cell -\pard\intbl\qc\fs18 0.07 (-0.34, 0.48) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 10/19 (52.6%) \cell -\pard\intbl\qc\fs18 4.26 (4.00, 4.52) \cell -\pard\intbl\qc\fs18 0.06 (-0.21, 0.33) \cell -\pard\intbl\qc\fs18 -0.47 (-0.83, -0.11) \cell -\pard\intbl\qc\fs18 -0.16 (-1.36, 1.04) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 18/19 (94.7%) \cell -\pard\intbl\qc\fs18 140.4 (139.3, 141.5) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 12/19 (63.2%) \cell -\pard\intbl\qc\fs18 142.0 (140.0, 144.0) \cell -\pard\intbl\qc\fs18 2.4 (-0.1, 4.9) \cell -\pard\intbl\qc\fs18 -4.3 (-7.4, -1.2) \cell -\pard\intbl\qc\fs18 -2.4 (-6.2, 1.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 11/19 (57.9%) \cell -\pard\intbl\qc\fs18 140.5 (139.1, 141.8) \cell -\pard\intbl\qc\fs18 0.2 (-1.8, 2.2) \cell -\pard\intbl\qc\fs18 -1.7 (-4.4, 1.1) \cell -\pard\intbl\qc\fs18 -0.4 (-3.0, 2.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 9/19 (47.4%) \cell -\pard\intbl\qc\fs18 139.9 (138.3, 141.4) \cell -\pard\intbl\qc\fs18 -0.6 (-2.8, 1.7) \cell -\pard\intbl\qc\fs18 -0.9 (-62.9, 61.0) \cell -\pard\intbl\qc\fs18 0.3 (-2.6, 3.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 31/33 (93.9%) \cell -\pard\intbl\qc\fs18 2.3131 (2.2837, 2.3424) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 17/32 (53.1%) \cell -\pard\intbl\qc\fs18 2.2646 (2.2189, 2.3103) \cell -\pard\intbl\qc\fs18 -0.0470 (-0.0990, 0.0051) \cell -\pard\intbl\qc\fs18 0.0234 (-0.0498, 0.0966) \cell -\pard\intbl\qc\fs18 0.0390 (-0.0295, 0.1076) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 11/30 (36.7%) \cell -\pard\intbl\qc\fs18 2.2636 (2.2095, 2.3177) \cell -\pard\intbl\qc\fs18 -0.0340 (-0.0850, 0.0170) \cell -\pard\intbl\qc\fs18 0.0386 (-0.0485, 0.1257) \cell -\pard\intbl\qc\fs18 0.0057 (-0.0547, 0.0662) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 16/27 (59.3%) \cell -\pard\intbl\qc\fs18 2.2891 (2.2318, 2.3465) \cell -\pard\intbl\qc\fs18 -0.0312 (-0.0847, 0.0223) \cell -\pard\intbl\qc\fs18 0.0273 (-0.0567, 0.1114) \cell -\pard\intbl\qc\fs18 0.0381 (-0.0263, 0.1025) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 32/33 (97.0%) \cell -\pard\intbl\qc\fs18 5.5042 (5.0416, 5.9668) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 16/32 (50.0%) \cell -\pard\intbl\qc\fs18 5.4781 (4.8872, 6.0691) \cell -\pard\intbl\qc\fs18 -0.1596 (-0.7538, 0.4346) \cell -\pard\intbl\qc\fs18 1.6584 (-0.2425, 3.5593) \cell -\pard\intbl\qc\fs18 0.5112 (-0.2929, 1.3152) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 12/30 (40.0%) \cell -\pard\intbl\qc\fs18 5.0468 (4.3048, 5.7888) \cell -\pard\intbl\qc\fs18 -0.3654 (-1.3988, 0.6679) \cell -\pard\intbl\qc\fs18 1.1664 (-0.0153, 2.3481) \cell -\pard\intbl\qc\fs18 0.4256 (-0.6595, 1.5107) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 14/27 (51.9%) \cell -\pard\intbl\qc\fs18 5.7849 (4.4980, 7.0718) \cell -\pard\intbl\qc\fs18 0.0634 (-0.9333, 1.0602) \cell -\pard\intbl\qc\fs18 1.4122 (-1.5146, 4.3390) \cell -\pard\intbl\qc\fs18 -0.3618 (-1.4765, 0.7529) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 31/33 (93.9%) \cell -\pard\intbl\qc\fs18 4.27 (4.13, 4.42) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 16/32 (50.0%) \cell -\pard\intbl\qc\fs18 4.30 (4.10, 4.50) \cell -\pard\intbl\qc\fs18 0.09 (-0.15, 0.33) \cell -\pard\intbl\qc\fs18 0.08 (-0.22, 0.37) \cell -\pard\intbl\qc\fs18 -0.07 (-0.37, 0.23) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 13/30 (43.3%) \cell -\pard\intbl\qc\fs18 4.17 (3.87, 4.47) \cell -\pard\intbl\qc\fs18 -0.08 (-0.34, 0.18) \cell -\pard\intbl\qc\fs18 -0.05 (-0.48, 0.38) \cell -\pard\intbl\qc\fs18 0.10 (-0.19, 0.40) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 15/27 (55.6%) \cell -\pard\intbl\qc\fs18 4.29 (4.10, 4.48) \cell -\pard\intbl\qc\fs18 -0.02 (-0.28, 0.24) \cell -\pard\intbl\qc\fs18 0.07 (-0.29, 0.43) \cell -\pard\intbl\qc\fs18 0.05 (-0.27, 0.37) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 32/33 (97.0%) \cell -\pard\intbl\qc\fs18 141.0 (139.9, 142.0) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 15/32 (46.9%) \cell -\pard\intbl\qc\fs18 139.3 (137.5, 141.2) \cell -\pard\intbl\qc\fs18 -0.6 (-2.1, 0.9) \cell -\pard\intbl\qc\fs18 0.4 (-2.8, 3.5) \cell -\pard\intbl\qc\fs18 1.4 (-0.6, 3.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 11/30 (36.7%) \cell -\pard\intbl\qc\fs18 139.5 (137.3, 141.6) \cell -\pard\intbl\qc\fs18 -1.6 (-3.8, 0.6) \cell -\pard\intbl\qc\fs18 2.4 (-0.3, 5.2) \cell -\pard\intbl\qc\fs18 2.1 (-0.4, 4.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4144 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6216 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8378 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10494 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 9/27 (33.3%) \cell -\pard\intbl\qc\fs18 140.7 (139.5, 141.9) \cell -\pard\intbl\qc\fs18 -1.4 (-4.2, 1.3) \cell -\pard\intbl\qc\fs18 3.0 (0.1, 5.9) \cell -\pard\intbl\qc\fs18 2.5 (-0.4, 5.4) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4144 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6216 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8378 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10494 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4144 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6216 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8378 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10494 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab01b/tsflab01b.rtf b/tests/testthat/_snaps/tsflab01b/tsflab01b.rtf new file mode 100644 index 00000000..25c8f8c0 --- /dev/null +++ b/tests/testthat/_snaps/tsflab01b/tsflab01b.rtf @@ -0,0 +1,11834 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2853 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5366 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7879 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10392 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB01b:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2853 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5366 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7879 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10392 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Albumin (g/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 39.552 (2.3950) \cell +\pard\intbl\qc\fs18 40.824 (2.6131) \cell +\pard\intbl\qc\fs18 40.102 (2.5600) \cell +\pard\intbl\qc\fs18 40.031 (2.4558) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 40.000 (32.00, 46.00) \cell +\pard\intbl\qc\fs18 41.000 (35.00, 46.00) \cell +\pard\intbl\qc\fs18 40.000 (32.00, 46.00) \cell +\pard\intbl\qc\fs18 40.000 (34.00, 46.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 38.525 (2.9246) \cell +\pard\intbl\qc\fs18 39.122 (2.7661) \cell +\pard\intbl\qc\fs18 38.791 (2.8578) \cell +\pard\intbl\qc\fs18 38.967 (2.9998) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 39.000 (32.00, 44.00) \cell +\pard\intbl\qc\fs18 39.000 (34.00, 46.00) \cell +\pard\intbl\qc\fs18 39.000 (32.00, 46.00) \cell +\pard\intbl\qc\fs18 39.000 (32.00, 46.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 39.541 (2.4534) \cell +\pard\intbl\qc\fs18 40.776 (2.5841) \cell +\pard\intbl\qc\fs18 40.091 (2.5756) \cell +\pard\intbl\qc\fs18 40.131 (2.4254) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -1.016 (2.8195) \cell +\pard\intbl\qc\fs18 -1.653 (2.0469) \cell +\pard\intbl\qc\fs18 -1.300 (2.5144) \cell +\pard\intbl\qc\fs18 -1.164 (2.5112) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.000 (-8.00, 7.00) \cell +\pard\intbl\qc\fs18 -1.000 (-7.00, 5.00) \cell +\pard\intbl\qc\fs18 -1.000 (-8.00, 7.00) \cell +\pard\intbl\qc\fs18 -2.000 (-6.00, 5.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.148 (-0.810, 1.105) \cell +\pard\intbl\qc\fs18 -0.489 (-1.351, 0.372) \cell +\pard\intbl\qc\fs18 -0.136 (-0.930, 0.658) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 38.723 (2.8567) \cell +\pard\intbl\qc\fs18 39.373 (2.7200) \cell +\pard\intbl\qc\fs18 39.061 (2.7911) \cell +\pard\intbl\qc\fs18 39.167 (2.9868) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 38.000 (34.00, 45.00) \cell +\pard\intbl\qc\fs18 39.000 (34.00, 45.00) \cell +\pard\intbl\qc\fs18 39.000 (34.00, 45.00) \cell +\pard\intbl\qc\fs18 39.000 (32.00, 47.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 39.617 (2.2220) \cell +\pard\intbl\qc\fs18 40.824 (2.6131) \cell +\pard\intbl\qc\fs18 40.245 (2.4956) \cell +\pard\intbl\qc\fs18 40.083 (2.4994) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.894 (2.4516) \cell +\pard\intbl\qc\fs18 -1.451 (2.5165) \cell +\pard\intbl\qc\fs18 -1.184 (2.4885) \cell +\pard\intbl\qc\fs18 -0.917 (2.6380) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.000 (-6.00, 6.00) \cell +\pard\intbl\qc\fs18 -2.000 (-6.00, 4.00) \cell +\pard\intbl\qc\fs18 -1.000 (-6.00, 6.00) \cell +\pard\intbl\qc\fs18 -1.000 (-6.00, 4.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.023 (-0.956, 1.003) \cell +\pard\intbl\qc\fs18 -0.534 (-1.506, 0.437) \cell +\pard\intbl\qc\fs18 -0.267 (-1.105, 0.571) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 38.575 (2.6592) \cell +\pard\intbl\qc\fs18 39.326 (2.9216) \cell +\pard\intbl\qc\fs18 38.977 (2.8116) \cell +\pard\intbl\qc\fs18 39.245 (2.6523) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 38.000 (33.00, 44.00) \cell +\pard\intbl\qc\fs18 39.000 (34.00, 45.00) \cell +\pard\intbl\qc\fs18 39.000 (33.00, 45.00) \cell +\pard\intbl\qc\fs18 40.000 (34.00, 44.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 39.400 (2.0854) \cell +\pard\intbl\qc\fs18 40.783 (2.7237) \cell +\pard\intbl\qc\fs18 40.140 (2.5306) \cell +\pard\intbl\qc\fs18 40.302 (2.3986) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.825 (2.2746) \cell +\pard\intbl\qc\fs18 -1.457 (2.1365) \cell +\pard\intbl\qc\fs18 -1.163 (2.2115) \cell +\pard\intbl\qc\fs18 -1.057 (2.2906) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.000 (-9.00, 3.00) \cell +\pard\intbl\qc\fs18 -1.000 (-6.00, 3.00) \cell +\pard\intbl\qc\fs18 -1.000 (-9.00, 3.00) \cell +\pard\intbl\qc\fs18 -1.000 (-6.00, 5.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.232 (-0.719, 1.182) \cell +\pard\intbl\qc\fs18 -0.400 (-1.284, 0.484) \cell +\pard\intbl\qc\fs18 -0.106 (-0.889, 0.676) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2.304 (0.1169) \cell +\pard\intbl\qc\fs18 2.298 (0.0950) \cell +\pard\intbl\qc\fs18 2.302 (0.1076) \cell +\pard\intbl\qc\fs18 2.307 (0.0993) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 2.295 (2.07, 2.62) \cell +\pard\intbl\qc\fs18 2.320 (2.07, 2.54) \cell +\pard\intbl\qc\fs18 2.295 (2.07, 2.62) \cell +\pard\intbl\qc\fs18 2.295 (2.02, 2.50) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2.297 (0.1222) \cell +\pard\intbl\qc\fs18 2.283 (0.1188) \cell +\pard\intbl\qc\fs18 2.291 (0.1204) \cell +\pard\intbl\qc\fs18 2.278 (0.0947) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 2.270 (2.05, 2.69) \cell +\pard\intbl\qc\fs18 2.270 (2.05, 2.57) \cell +\pard\intbl\qc\fs18 2.270 (2.05, 2.69) \cell +\pard\intbl\qc\fs18 2.270 (2.02, 2.52) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 2.304 (0.1206) \cell +\pard\intbl\qc\fs18 2.297 (0.0967) \cell +\pard\intbl\qc\fs18 2.301 (0.1102) \cell +\pard\intbl\qc\fs18 2.305 (0.0997) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.007 (0.1044) \cell +\pard\intbl\qc\fs18 -0.014 (0.1006) \cell +\pard\intbl\qc\fs18 -0.010 (0.1023) \cell +\pard\intbl\qc\fs18 -0.028 (0.0945) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.000 (-0.30, 0.25) \cell +\pard\intbl\qc\fs18 0.000 (-0.22, 0.17) \cell +\pard\intbl\qc\fs18 0.000 (-0.30, 0.25) \cell +\pard\intbl\qc\fs18 -0.025 (-0.22, 0.17) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.020 (-0.015, 0.056) \cell +\pard\intbl\qc\fs18 0.014 (-0.023, 0.051) \cell +\pard\intbl\qc\fs18 0.018 (-0.013, 0.048) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2.295 (0.1046) \cell +\pard\intbl\qc\fs18 2.282 (0.0974) \cell +\pard\intbl\qc\fs18 2.288 (0.1006) \cell +\pard\intbl\qc\fs18 2.286 (0.0898) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 2.295 (2.10, 2.57) \cell +\pard\intbl\qc\fs18 2.295 (2.05, 2.47) \cell +\pard\intbl\qc\fs18 2.295 (2.05, 2.57) \cell +\pard\intbl\qc\fs18 2.295 (2.12, 2.52) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 2.302 (0.1065) \cell +\pard\intbl\qc\fs18 2.298 (0.0950) \cell +\pard\intbl\qc\fs18 2.300 (0.1002) \cell +\pard\intbl\qc\fs18 2.304 (0.1002) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.007 (0.0826) \cell +\pard\intbl\qc\fs18 -0.017 (0.0940) \cell +\pard\intbl\qc\fs18 -0.012 (0.0884) \cell +\pard\intbl\qc\fs18 -0.018 (0.0943) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.000 (-0.17, 0.20) \cell +\pard\intbl\qc\fs18 0.000 (-0.22, 0.17) \cell +\pard\intbl\qc\fs18 0.000 (-0.22, 0.20) \cell +\pard\intbl\qc\fs18 -0.025 (-0.20, 0.22) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.011 (-0.023, 0.045) \cell +\pard\intbl\qc\fs18 0.002 (-0.034, 0.037) \cell +\pard\intbl\qc\fs18 0.006 (-0.024, 0.036) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2.298 (0.1096) \cell +\pard\intbl\qc\fs18 2.275 (0.0930) \cell +\pard\intbl\qc\fs18 2.286 (0.1013) \cell +\pard\intbl\qc\fs18 2.299 (0.0895) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 2.295 (2.10, 2.54) \cell +\pard\intbl\qc\fs18 2.295 (2.00, 2.52) \cell +\pard\intbl\qc\fs18 2.295 (2.00, 2.54) \cell +\pard\intbl\qc\fs18 2.295 (2.07, 2.50) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 2.312 (0.0997) \cell +\pard\intbl\qc\fs18 2.301 (0.0946) \cell +\pard\intbl\qc\fs18 2.306 (0.0967) \cell +\pard\intbl\qc\fs18 2.304 (0.1014) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.014 (0.0834) \cell +\pard\intbl\qc\fs18 -0.026 (0.0988) \cell +\pard\intbl\qc\fs18 -0.020 (0.0916) \cell +\pard\intbl\qc\fs18 -0.005 (0.0955) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.025 (-0.17, 0.17) \cell +\pard\intbl\qc\fs18 -0.025 (-0.27, 0.20) \cell +\pard\intbl\qc\fs18 -0.025 (-0.27, 0.20) \cell +\pard\intbl\qc\fs18 0.000 (-0.22, 0.17) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -0.009 (-0.045, 0.027) \cell +\pard\intbl\qc\fs18 -0.021 (-0.059, 0.018) \cell +\pard\intbl\qc\fs18 -0.015 (-0.047, 0.017) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Chloride (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 105.91 (3.288) \cell +\pard\intbl\qc\fs18 105.18 (3.664) \cell +\pard\intbl\qc\fs18 105.59 (3.460) \cell +\pard\intbl\qc\fs18 105.17 (3.115) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 106.00 (98.0, 114.0) \cell +\pard\intbl\qc\fs18 105.00 (91.0, 112.0) \cell +\pard\intbl\qc\fs18 106.00 (91.0, 114.0) \cell +\pard\intbl\qc\fs18 105.50 (96.0, 112.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 105.33 (3.385) \cell +\pard\intbl\qc\fs18 104.18 (3.575) \cell +\pard\intbl\qc\fs18 104.82 (3.501) \cell +\pard\intbl\qc\fs18 106.26 (3.203) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 105.00 (97.0, 114.0) \cell +\pard\intbl\qc\fs18 104.00 (96.0, 112.0) \cell +\pard\intbl\qc\fs18 105.00 (96.0, 114.0) \cell +\pard\intbl\qc\fs18 107.00 (98.0, 114.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 105.77 (3.359) \cell +\pard\intbl\qc\fs18 105.06 (3.642) \cell +\pard\intbl\qc\fs18 105.45 (3.490) \cell +\pard\intbl\qc\fs18 105.16 (3.163) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.44 (3.324) \cell +\pard\intbl\qc\fs18 -0.88 (4.161) \cell +\pard\intbl\qc\fs18 -0.64 (3.709) \cell +\pard\intbl\qc\fs18 1.10 (3.227) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-7.0, 8.0) \cell +\pard\intbl\qc\fs18 -1.00 (-15.0, 9.0) \cell +\pard\intbl\qc\fs18 -1.00 (-15.0, 9.0) \cell +\pard\intbl\qc\fs18 0.50 (-7.0, 10.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -1.54 (-2.71, -0.37) \cell +\pard\intbl\qc\fs18 -1.97 (-3.41, -0.54) \cell +\pard\intbl\qc\fs18 -1.73 (-2.80, -0.66) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 104.98 (2.809) \cell +\pard\intbl\qc\fs18 104.90 (3.775) \cell +\pard\intbl\qc\fs18 104.94 (3.330) \cell +\pard\intbl\qc\fs18 105.51 (3.608) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 105.00 (98.0, 112.0) \cell +\pard\intbl\qc\fs18 105.00 (95.0, 111.0) \cell +\pard\intbl\qc\fs18 105.00 (95.0, 112.0) \cell +\pard\intbl\qc\fs18 106.00 (98.0, 115.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 105.87 (3.097) \cell +\pard\intbl\qc\fs18 105.18 (3.664) \cell +\pard\intbl\qc\fs18 105.51 (3.405) \cell +\pard\intbl\qc\fs18 105.16 (3.189) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.89 (3.607) \cell +\pard\intbl\qc\fs18 -0.27 (4.243) \cell +\pard\intbl\qc\fs18 -0.57 (3.943) \cell +\pard\intbl\qc\fs18 0.34 (4.527) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-8.0, 7.0) \cell +\pard\intbl\qc\fs18 -1.00 (-8.0, 9.0) \cell +\pard\intbl\qc\fs18 -1.00 (-8.0, 9.0) \cell +\pard\intbl\qc\fs18 0.00 (-9.0, 12.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -1.24 (-2.79, 0.31) \cell +\pard\intbl\qc\fs18 -0.62 (-2.26, 1.03) \cell +\pard\intbl\qc\fs18 -0.92 (-2.31, 0.48) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 106.17 (3.305) \cell +\pard\intbl\qc\fs18 105.19 (3.174) \cell +\pard\intbl\qc\fs18 105.65 (3.255) \cell +\pard\intbl\qc\fs18 105.36 (3.153) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 106.00 (97.0, 114.0) \cell +\pard\intbl\qc\fs18 106.00 (96.0, 111.0) \cell +\pard\intbl\qc\fs18 106.00 (96.0, 114.0) \cell +\pard\intbl\qc\fs18 105.00 (95.0, 111.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 105.88 (3.210) \cell +\pard\intbl\qc\fs18 105.40 (3.167) \cell +\pard\intbl\qc\fs18 105.63 (3.178) \cell +\pard\intbl\qc\fs18 105.09 (3.301) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.29 (3.865) \cell +\pard\intbl\qc\fs18 -0.21 (3.587) \cell +\pard\intbl\qc\fs18 0.02 (3.708) \cell +\pard\intbl\qc\fs18 0.27 (3.577) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-8.0, 10.0) \cell +\pard\intbl\qc\fs18 0.00 (-7.0, 8.0) \cell +\pard\intbl\qc\fs18 0.00 (-8.0, 10.0) \cell +\pard\intbl\qc\fs18 0.00 (-7.0, 9.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.01 (-1.51, 1.54) \cell +\pard\intbl\qc\fs18 -0.49 (-1.90, 0.93) \cell +\pard\intbl\qc\fs18 -0.25 (-1.48, 0.98) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Creatinine Kinase (U/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 85.97 (43.917) \cell +\pard\intbl\qc\fs18 106.71 (75.766) \cell +\pard\intbl\qc\fs18 94.93 (60.396) \cell +\pard\intbl\qc\fs18 84.52 (41.317) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 71.00 (31.0, 223.0) \cell +\pard\intbl\qc\fs18 86.00 (39.0, 444.0) \cell +\pard\intbl\qc\fs18 77.50 (31.0, 444.0) \cell +\pard\intbl\qc\fs18 77.00 (27.0, 214.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 94.38 (84.067) \cell +\pard\intbl\qc\fs18 91.35 (41.370) \cell +\pard\intbl\qc\fs18 93.03 (68.163) \cell +\pard\intbl\qc\fs18 94.10 (73.604) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 72.00 (28.0, 601.0) \cell +\pard\intbl\qc\fs18 76.00 (31.0, 212.0) \cell +\pard\intbl\qc\fs18 74.50 (28.0, 601.0) \cell +\pard\intbl\qc\fs18 76.00 (29.0, 536.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 86.46 (43.982) \cell +\pard\intbl\qc\fs18 108.10 (76.991) \cell +\pard\intbl\qc\fs18 96.10 (61.579) \cell +\pard\intbl\qc\fs18 85.90 (41.564) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 7.92 (72.415) \cell +\pard\intbl\qc\fs18 -16.76 (61.501) \cell +\pard\intbl\qc\fs18 -3.07 (68.585) \cell +\pard\intbl\qc\fs18 8.20 (65.737) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -2.00 (-99.0, 508.0) \cell +\pard\intbl\qc\fs18 -6.00 (-344.0, 92.0) \cell +\pard\intbl\qc\fs18 -3.50 (-344.0, 508.0) \cell +\pard\intbl\qc\fs18 -2.00 (-162.0, 421.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -0.28 (-25.07, 24.52) \cell +\pard\intbl\qc\fs18 -24.95 (-49.08, -0.83) \cell +\pard\intbl\qc\fs18 -11.27 (-32.36, 9.82) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 79.87 (42.290) \cell +\pard\intbl\qc\fs18 102.22 (56.962) \cell +\pard\intbl\qc\fs18 91.50 (51.445) \cell +\pard\intbl\qc\fs18 86.53 (44.028) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 71.00 (26.0, 282.0) \cell +\pard\intbl\qc\fs18 82.00 (30.0, 293.0) \cell +\pard\intbl\qc\fs18 74.50 (26.0, 293.0) \cell +\pard\intbl\qc\fs18 76.00 (27.0, 206.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 82.15 (36.269) \cell +\pard\intbl\qc\fs18 106.71 (75.766) \cell +\pard\intbl\qc\fs18 94.93 (61.114) \cell +\pard\intbl\qc\fs18 86.28 (41.622) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -2.28 (26.807) \cell +\pard\intbl\qc\fs18 -4.49 (59.329) \cell +\pard\intbl\qc\fs18 -3.43 (46.438) \cell +\pard\intbl\qc\fs18 0.25 (34.818) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-95.0, 59.0) \cell +\pard\intbl\qc\fs18 2.00 (-321.0, 126.0) \cell +\pard\intbl\qc\fs18 1.00 (-321.0, 126.0) \cell +\pard\intbl\qc\fs18 0.00 (-164.0, 99.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -2.53 (-14.34, 9.29) \cell +\pard\intbl\qc\fs18 -4.74 (-23.55, 14.07) \cell +\pard\intbl\qc\fs18 -3.68 (-16.52, 9.16) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 76.53 (41.125) \cell +\pard\intbl\qc\fs18 137.61 (270.225) \cell +\pard\intbl\qc\fs18 109.20 (200.932) \cell +\pard\intbl\qc\fs18 91.64 (44.796) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 67.50 (34.0, 289.0) \cell +\pard\intbl\qc\fs18 76.00 (27.0, 1860.0) \cell +\pard\intbl\qc\fs18 74.50 (27.0, 1860.0) \cell +\pard\intbl\qc\fs18 85.00 (30.0, 224.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 79.48 (36.435) \cell +\pard\intbl\qc\fs18 107.46 (77.939) \cell +\pard\intbl\qc\fs18 94.44 (63.420) \cell +\pard\intbl\qc\fs18 87.51 (42.130) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -2.95 (28.707) \cell +\pard\intbl\qc\fs18 30.15 (221.503) \cell +\pard\intbl\qc\fs18 14.76 (163.183) \cell +\pard\intbl\qc\fs18 4.13 (41.411) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -2.00 (-114.0, 66.0) \cell +\pard\intbl\qc\fs18 -9.00 (-281.0, 1416.0) \cell +\pard\intbl\qc\fs18 -5.00 (-281.0, 1416.0) \cell +\pard\intbl\qc\fs18 1.00 (-161.0, 100.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -7.08 (-21.54, 7.37) \cell +\pard\intbl\qc\fs18 26.02 (-40.64, 92.68) \cell +\pard\intbl\qc\fs18 10.62 (-26.06, 47.31) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.29 (0.948) \cell +\pard\intbl\qc\fs18 5.53 (1.557) \cell +\pard\intbl\qc\fs18 5.39 (1.248) \cell +\pard\intbl\qc\fs18 5.46 (1.217) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 5.11 (2.9, 8.7) \cell +\pard\intbl\qc\fs18 5.05 (3.5, 11.9) \cell +\pard\intbl\qc\fs18 5.08 (2.9, 11.9) \cell +\pard\intbl\qc\fs18 5.25 (3.8, 10.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.54 (1.886) \cell +\pard\intbl\qc\fs18 6.53 (3.531) \cell +\pard\intbl\qc\fs18 5.98 (2.773) \cell +\pard\intbl\qc\fs18 5.50 (1.262) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 5.27 (3.7, 17.5) \cell +\pard\intbl\qc\fs18 5.55 (3.3, 23.3) \cell +\pard\intbl\qc\fs18 5.33 (3.3, 23.3) \cell +\pard\intbl\qc\fs18 5.27 (3.3, 10.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 5.27 (0.879) \cell +\pard\intbl\qc\fs18 5.54 (1.587) \cell +\pard\intbl\qc\fs18 5.39 (1.246) \cell +\pard\intbl\qc\fs18 5.46 (1.243) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.27 (1.724) \cell +\pard\intbl\qc\fs18 0.99 (2.536) \cell +\pard\intbl\qc\fs18 0.59 (2.144) \cell +\pard\intbl\qc\fs18 0.04 (1.364) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.11 (-2.7, 10.5) \cell +\pard\intbl\qc\fs18 0.22 (-1.7, 13.8) \cell +\pard\intbl\qc\fs18 0.17 (-2.7, 13.8) \cell +\pard\intbl\qc\fs18 0.00 (-4.1, 4.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.23 (-0.33, 0.79) \cell +\pard\intbl\qc\fs18 0.95 (0.14, 1.75) \cell +\pard\intbl\qc\fs18 0.55 (0.02, 1.08) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.48 (1.599) \cell +\pard\intbl\qc\fs18 6.10 (2.043) \cell +\pard\intbl\qc\fs18 5.81 (1.865) \cell +\pard\intbl\qc\fs18 5.50 (1.220) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 5.16 (3.1, 13.3) \cell +\pard\intbl\qc\fs18 5.61 (4.0, 14.2) \cell +\pard\intbl\qc\fs18 5.33 (3.1, 14.2) \cell +\pard\intbl\qc\fs18 5.22 (3.0, 9.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 5.35 (0.810) \cell +\pard\intbl\qc\fs18 5.53 (1.557) \cell +\pard\intbl\qc\fs18 5.45 (1.260) \cell +\pard\intbl\qc\fs18 5.47 (1.251) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.13 (1.360) \cell +\pard\intbl\qc\fs18 0.57 (1.488) \cell +\pard\intbl\qc\fs18 0.37 (1.439) \cell +\pard\intbl\qc\fs18 0.03 (1.500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.06 (-2.2, 6.3) \cell +\pard\intbl\qc\fs18 0.28 (-4.6, 4.6) \cell +\pard\intbl\qc\fs18 0.14 (-4.6, 6.3) \cell +\pard\intbl\qc\fs18 -0.08 (-4.8, 4.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.10 (-0.46, 0.65) \cell +\pard\intbl\qc\fs18 0.54 (-0.02, 1.10) \cell +\pard\intbl\qc\fs18 0.33 (-0.15, 0.81) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.43 (1.582) \cell +\pard\intbl\qc\fs18 6.23 (3.273) \cell +\pard\intbl\qc\fs18 5.86 (2.642) \cell +\pard\intbl\qc\fs18 5.57 (1.521) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 5.11 (4.1, 14.2) \cell +\pard\intbl\qc\fs18 5.22 (4.2, 24.0) \cell +\pard\intbl\qc\fs18 5.13 (4.1, 24.0) \cell +\pard\intbl\qc\fs18 5.16 (3.3, 12.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 5.32 (0.782) \cell +\pard\intbl\qc\fs18 5.54 (1.617) \cell +\pard\intbl\qc\fs18 5.44 (1.295) \cell +\pard\intbl\qc\fs18 5.46 (1.330) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.11 (1.391) \cell +\pard\intbl\qc\fs18 0.68 (2.635) \cell +\pard\intbl\qc\fs18 0.41 (2.156) \cell +\pard\intbl\qc\fs18 0.11 (1.493) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.11 (-2.3, 7.2) \cell +\pard\intbl\qc\fs18 0.19 (-3.3, 14.8) \cell +\pard\intbl\qc\fs18 0.06 (-3.3, 14.8) \cell +\pard\intbl\qc\fs18 -0.06 (-3.3, 4.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.00 (-0.60, 0.60) \cell +\pard\intbl\qc\fs18 0.58 (-0.30, 1.45) \cell +\pard\intbl\qc\fs18 0.31 (-0.31, 0.92) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Phosphate (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.14 (0.125) \cell +\pard\intbl\qc\fs18 1.16 (0.141) \cell +\pard\intbl\qc\fs18 1.15 (0.132) \cell +\pard\intbl\qc\fs18 1.16 (0.142) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.11 (0.9, 1.5) \cell +\pard\intbl\qc\fs18 1.16 (0.8, 1.5) \cell +\pard\intbl\qc\fs18 1.16 (0.8, 1.5) \cell +\pard\intbl\qc\fs18 1.16 (0.8, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.16 (0.152) \cell +\pard\intbl\qc\fs18 1.16 (0.179) \cell +\pard\intbl\qc\fs18 1.16 (0.164) \cell +\pard\intbl\qc\fs18 1.16 (0.147) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.16 (0.9, 1.5) \cell +\pard\intbl\qc\fs18 1.16 (0.7, 1.5) \cell +\pard\intbl\qc\fs18 1.16 (0.7, 1.5) \cell +\pard\intbl\qc\fs18 1.13 (0.9, 1.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 1.14 (0.124) \cell +\pard\intbl\qc\fs18 1.17 (0.143) \cell +\pard\intbl\qc\fs18 1.15 (0.133) \cell +\pard\intbl\qc\fs18 1.16 (0.137) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.01 (0.166) \cell +\pard\intbl\qc\fs18 0.00 (0.193) \cell +\pard\intbl\qc\fs18 0.01 (0.178) \cell +\pard\intbl\qc\fs18 0.00 (0.171) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-0.4, 0.5) \cell +\pard\intbl\qc\fs18 0.03 (-0.5, 0.5) \cell +\pard\intbl\qc\fs18 0.00 (-0.5, 0.5) \cell +\pard\intbl\qc\fs18 0.00 (-0.5, 0.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.01 (-0.05, 0.07) \cell +\pard\intbl\qc\fs18 0.00 (-0.07, 0.06) \cell +\pard\intbl\qc\fs18 0.00 (-0.05, 0.06) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 97 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.14 (0.138) \cell +\pard\intbl\qc\fs18 1.15 (0.174) \cell +\pard\intbl\qc\fs18 1.15 (0.157) \cell +\pard\intbl\qc\fs18 1.15 (0.147) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.13 (0.9, 1.4) \cell +\pard\intbl\qc\fs18 1.16 (0.7, 1.5) \cell +\pard\intbl\qc\fs18 1.13 (0.7, 1.5) \cell +\pard\intbl\qc\fs18 1.16 (0.5, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 1.16 (0.121) \cell +\pard\intbl\qc\fs18 1.16 (0.141) \cell +\pard\intbl\qc\fs18 1.16 (0.131) \cell +\pard\intbl\qc\fs18 1.16 (0.136) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.01 (0.147) \cell +\pard\intbl\qc\fs18 -0.02 (0.164) \cell +\pard\intbl\qc\fs18 -0.01 (0.155) \cell +\pard\intbl\qc\fs18 -0.01 (0.172) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.03 (-0.4, 0.3) \cell +\pard\intbl\qc\fs18 0.00 (-0.4, 0.3) \cell +\pard\intbl\qc\fs18 0.00 (-0.4, 0.3) \cell +\pard\intbl\qc\fs18 0.00 (-0.6, 0.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.00 (-0.06, 0.06) \cell +\pard\intbl\qc\fs18 0.00 (-0.07, 0.06) \cell +\pard\intbl\qc\fs18 0.00 (-0.06, 0.05) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.17 (0.165) \cell +\pard\intbl\qc\fs18 1.17 (0.161) \cell +\pard\intbl\qc\fs18 1.17 (0.162) \cell +\pard\intbl\qc\fs18 1.18 (0.141) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.19 (0.8, 1.5) \cell +\pard\intbl\qc\fs18 1.16 (0.8, 1.5) \cell +\pard\intbl\qc\fs18 1.19 (0.8, 1.5) \cell +\pard\intbl\qc\fs18 1.19 (0.9, 1.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 1.15 (0.119) \cell +\pard\intbl\qc\fs18 1.16 (0.135) \cell +\pard\intbl\qc\fs18 1.16 (0.127) \cell +\pard\intbl\qc\fs18 1.15 (0.132) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.02 (0.165) \cell +\pard\intbl\qc\fs18 0.00 (0.177) \cell +\pard\intbl\qc\fs18 0.01 (0.171) \cell +\pard\intbl\qc\fs18 0.04 (0.143) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-0.4, 0.4) \cell +\pard\intbl\qc\fs18 0.00 (-0.3, 0.6) \cell +\pard\intbl\qc\fs18 0.00 (-0.4, 0.6) \cell +\pard\intbl\qc\fs18 0.03 (-0.3, 0.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -0.02 (-0.08, 0.04) \cell +\pard\intbl\qc\fs18 -0.03 (-0.10, 0.03) \cell +\pard\intbl\qc\fs18 -0.03 (-0.08, 0.03) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 4.31 (0.372) \cell +\pard\intbl\qc\fs18 4.31 (0.333) \cell +\pard\intbl\qc\fs18 4.31 (0.354) \cell +\pard\intbl\qc\fs18 4.26 (0.459) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 4.30 (3.4, 5.1) \cell +\pard\intbl\qc\fs18 4.40 (3.6, 5.0) \cell +\pard\intbl\qc\fs18 4.30 (3.4, 5.1) \cell +\pard\intbl\qc\fs18 4.20 (3.5, 5.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 4.27 (0.419) \cell +\pard\intbl\qc\fs18 4.28 (0.382) \cell +\pard\intbl\qc\fs18 4.27 (0.401) \cell +\pard\intbl\qc\fs18 4.24 (0.423) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 4.20 (3.3, 5.3) \cell +\pard\intbl\qc\fs18 4.30 (3.6, 5.4) \cell +\pard\intbl\qc\fs18 4.30 (3.3, 5.4) \cell +\pard\intbl\qc\fs18 4.20 (3.5, 5.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 4.30 (0.373) \cell +\pard\intbl\qc\fs18 4.30 (0.337) \cell +\pard\intbl\qc\fs18 4.30 (0.356) \cell +\pard\intbl\qc\fs18 4.26 (0.465) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.04 (0.400) \cell +\pard\intbl\qc\fs18 -0.02 (0.457) \cell +\pard\intbl\qc\fs18 -0.03 (0.425) \cell +\pard\intbl\qc\fs18 -0.01 (0.415) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-1.2, 0.9) \cell +\pard\intbl\qc\fs18 0.10 (-1.0, 0.9) \cell +\pard\intbl\qc\fs18 0.00 (-1.2, 0.9) \cell +\pard\intbl\qc\fs18 0.00 (-0.9, 1.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -0.02 (-0.17, 0.12) \cell +\pard\intbl\qc\fs18 0.00 (-0.17, 0.16) \cell +\pard\intbl\qc\fs18 -0.01 (-0.15, 0.12) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 97 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 4.23 (0.432) \cell +\pard\intbl\qc\fs18 4.24 (0.319) \cell +\pard\intbl\qc\fs18 4.24 (0.375) \cell +\pard\intbl\qc\fs18 4.20 (0.384) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 4.20 (3.1, 5.3) \cell +\pard\intbl\qc\fs18 4.30 (3.5, 5.2) \cell +\pard\intbl\qc\fs18 4.20 (3.1, 5.3) \cell +\pard\intbl\qc\fs18 4.20 (3.4, 5.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 4.29 (0.353) \cell +\pard\intbl\qc\fs18 4.31 (0.333) \cell +\pard\intbl\qc\fs18 4.30 (0.341) \cell +\pard\intbl\qc\fs18 4.24 (0.456) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.06 (0.349) \cell +\pard\intbl\qc\fs18 -0.06 (0.432) \cell +\pard\intbl\qc\fs18 -0.06 (0.393) \cell +\pard\intbl\qc\fs18 -0.04 (0.413) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-0.7, 0.5) \cell +\pard\intbl\qc\fs18 -0.10 (-1.0, 1.0) \cell +\pard\intbl\qc\fs18 -0.10 (-1.0, 1.0) \cell +\pard\intbl\qc\fs18 -0.10 (-0.9, 1.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -0.02 (-0.16, 0.13) \cell +\pard\intbl\qc\fs18 -0.03 (-0.18, 0.13) \cell +\pard\intbl\qc\fs18 -0.02 (-0.15, 0.11) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 4.30 (0.344) \cell +\pard\intbl\qc\fs18 4.21 (0.318) \cell +\pard\intbl\qc\fs18 4.26 (0.332) \cell +\pard\intbl\qc\fs18 4.30 (0.325) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 4.30 (3.7, 5.3) \cell +\pard\intbl\qc\fs18 4.20 (3.3, 4.9) \cell +\pard\intbl\qc\fs18 4.20 (3.3, 5.3) \cell +\pard\intbl\qc\fs18 4.30 (3.5, 4.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 4.31 (0.360) \cell +\pard\intbl\qc\fs18 4.31 (0.320) \cell +\pard\intbl\qc\fs18 4.31 (0.338) \cell +\pard\intbl\qc\fs18 4.23 (0.454) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00 (0.410) \cell +\pard\intbl\qc\fs18 -0.10 (0.416) \cell +\pard\intbl\qc\fs18 -0.06 (0.414) \cell +\pard\intbl\qc\fs18 0.07 (0.461) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-0.9, 1.0) \cell +\pard\intbl\qc\fs18 -0.10 (-0.9, 0.6) \cell +\pard\intbl\qc\fs18 0.00 (-0.9, 1.0) \cell +\pard\intbl\qc\fs18 0.10 (-1.1, 1.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -0.08 (-0.25, 0.10) \cell +\pard\intbl\qc\fs18 -0.18 (-0.35, 0.00) \cell +\pard\intbl\qc\fs18 -0.13 (-0.28, 0.02) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Protein (g/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 70.13 (4.313) \cell +\pard\intbl\qc\fs18 71.51 (3.646) \cell +\pard\intbl\qc\fs18 70.73 (4.080) \cell +\pard\intbl\qc\fs18 71.09 (4.227) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 70.00 (59.0, 84.0) \cell +\pard\intbl\qc\fs18 72.00 (62.0, 79.0) \cell +\pard\intbl\qc\fs18 71.00 (59.0, 84.0) \cell +\pard\intbl\qc\fs18 71.00 (61.0, 82.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 69.21 (4.329) \cell +\pard\intbl\qc\fs18 69.78 (4.069) \cell +\pard\intbl\qc\fs18 69.46 (4.205) \cell +\pard\intbl\qc\fs18 69.34 (4.690) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 69.00 (61.0, 84.0) \cell +\pard\intbl\qc\fs18 70.00 (61.0, 81.0) \cell +\pard\intbl\qc\fs18 70.00 (61.0, 84.0) \cell +\pard\intbl\qc\fs18 69.00 (59.0, 80.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 69.93 (4.385) \cell +\pard\intbl\qc\fs18 71.59 (3.685) \cell +\pard\intbl\qc\fs18 70.67 (4.153) \cell +\pard\intbl\qc\fs18 71.11 (4.270) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.72 (3.484) \cell +\pard\intbl\qc\fs18 -1.82 (3.551) \cell +\pard\intbl\qc\fs18 -1.21 (3.540) \cell +\pard\intbl\qc\fs18 -1.77 (4.441) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-10.0, 9.0) \cell +\pard\intbl\qc\fs18 -1.00 (-11.0, 7.0) \cell +\pard\intbl\qc\fs18 -1.00 (-11.0, 9.0) \cell +\pard\intbl\qc\fs18 -3.00 (-8.0, 16.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 1.05 (-0.37, 2.48) \cell +\pard\intbl\qc\fs18 -0.04 (-1.55, 1.46) \cell +\pard\intbl\qc\fs18 0.57 (-0.74, 1.87) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 68.83 (4.641) \cell +\pard\intbl\qc\fs18 70.04 (4.103) \cell +\pard\intbl\qc\fs18 69.46 (4.389) \cell +\pard\intbl\qc\fs18 69.39 (4.051) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 68.00 (59.0, 81.0) \cell +\pard\intbl\qc\fs18 70.00 (63.0, 79.0) \cell +\pard\intbl\qc\fs18 69.00 (59.0, 81.0) \cell +\pard\intbl\qc\fs18 69.00 (61.0, 81.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 69.83 (4.125) \cell +\pard\intbl\qc\fs18 71.51 (3.646) \cell +\pard\intbl\qc\fs18 70.70 (3.954) \cell +\pard\intbl\qc\fs18 71.08 (4.298) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -1.00 (3.532) \cell +\pard\intbl\qc\fs18 -1.47 (3.602) \cell +\pard\intbl\qc\fs18 -1.24 (3.558) \cell +\pard\intbl\qc\fs18 -1.69 (3.849) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-9.0, 7.0) \cell +\pard\intbl\qc\fs18 -2.00 (-11.0, 7.0) \cell +\pard\intbl\qc\fs18 -1.00 (-11.0, 7.0) \cell +\pard\intbl\qc\fs18 -2.00 (-9.0, 8.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.69 (-0.73, 2.10) \cell +\pard\intbl\qc\fs18 0.22 (-1.18, 1.62) \cell +\pard\intbl\qc\fs18 0.44 (-0.76, 1.65) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 68.95 (4.742) \cell +\pard\intbl\qc\fs18 69.87 (4.276) \cell +\pard\intbl\qc\fs18 69.44 (4.500) \cell +\pard\intbl\qc\fs18 70.00 (3.863) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 68.50 (60.0, 83.0) \cell +\pard\intbl\qc\fs18 70.00 (60.0, 79.0) \cell +\pard\intbl\qc\fs18 69.00 (60.0, 83.0) \cell +\pard\intbl\qc\fs18 70.00 (62.0, 78.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 69.62 (4.214) \cell +\pard\intbl\qc\fs18 71.64 (3.674) \cell +\pard\intbl\qc\fs18 70.69 (4.044) \cell +\pard\intbl\qc\fs18 71.25 (4.178) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.67 (4.059) \cell +\pard\intbl\qc\fs18 -1.77 (3.607) \cell +\pard\intbl\qc\fs18 -1.25 (3.844) \cell +\pard\intbl\qc\fs18 -1.25 (3.743) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.50 (-14.0, 10.0) \cell +\pard\intbl\qc\fs18 -1.00 (-11.0, 4.0) \cell +\pard\intbl\qc\fs18 -1.00 (-14.0, 10.0) \cell +\pard\intbl\qc\fs18 -2.00 (-8.0, 9.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.59 (-1.01, 2.19) \cell +\pard\intbl\qc\fs18 -0.51 (-1.96, 0.94) \cell +\pard\intbl\qc\fs18 0.01 (-1.28, 1.29) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 139.99 (2.863) \cell +\pard\intbl\qc\fs18 140.20 (3.188) \cell +\pard\intbl\qc\fs18 140.08 (2.996) \cell +\pard\intbl\qc\fs18 140.34 (2.784) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 140.00 (133.0, 145.0) \cell +\pard\intbl\qc\fs18 140.00 (133.0, 148.0) \cell +\pard\intbl\qc\fs18 140.00 (133.0, 148.0) \cell +\pard\intbl\qc\fs18 140.00 (130.0, 147.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 139.39 (2.716) \cell +\pard\intbl\qc\fs18 138.94 (3.139) \cell +\pard\intbl\qc\fs18 139.19 (2.907) \cell +\pard\intbl\qc\fs18 140.52 (2.696) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 139.00 (135.0, 147.0) \cell +\pard\intbl\qc\fs18 139.00 (131.0, 147.0) \cell +\pard\intbl\qc\fs18 139.00 (131.0, 147.0) \cell +\pard\intbl\qc\fs18 141.00 (129.0, 149.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 139.85 (2.756) \cell +\pard\intbl\qc\fs18 140.00 (3.035) \cell +\pard\intbl\qc\fs18 139.92 (2.871) \cell +\pard\intbl\qc\fs18 140.44 (2.779) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.46 (2.796) \cell +\pard\intbl\qc\fs18 -1.06 (2.996) \cell +\pard\intbl\qc\fs18 -0.73 (2.889) \cell +\pard\intbl\qc\fs18 0.08 (3.271) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-6.0, 7.0) \cell +\pard\intbl\qc\fs18 -1.00 (-10.0, 5.0) \cell +\pard\intbl\qc\fs18 -1.00 (-10.0, 7.0) \cell +\pard\intbl\qc\fs18 0.00 (-8.0, 11.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -0.54 (-1.63, 0.55) \cell +\pard\intbl\qc\fs18 -1.14 (-2.32, 0.04) \cell +\pard\intbl\qc\fs18 -0.81 (-1.80, 0.18) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 139.89 (2.656) \cell +\pard\intbl\qc\fs18 139.59 (3.008) \cell +\pard\intbl\qc\fs18 139.73 (2.834) \cell +\pard\intbl\qc\fs18 139.89 (2.751) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 140.00 (133.0, 145.0) \cell +\pard\intbl\qc\fs18 139.00 (134.0, 147.0) \cell +\pard\intbl\qc\fs18 140.00 (133.0, 147.0) \cell +\pard\intbl\qc\fs18 140.00 (132.0, 146.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 139.94 (2.769) \cell +\pard\intbl\qc\fs18 140.20 (3.188) \cell +\pard\intbl\qc\fs18 140.07 (2.982) \cell +\pard\intbl\qc\fs18 140.39 (2.783) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.04 (3.329) \cell +\pard\intbl\qc\fs18 -0.61 (3.550) \cell +\pard\intbl\qc\fs18 -0.34 (3.440) \cell +\pard\intbl\qc\fs18 -0.51 (3.994) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-7.0, 7.0) \cell +\pard\intbl\qc\fs18 0.00 (-8.0, 7.0) \cell +\pard\intbl\qc\fs18 0.00 (-8.0, 7.0) \cell +\pard\intbl\qc\fs18 -1.00 (-9.0, 13.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.47 (-0.93, 1.86) \cell +\pard\intbl\qc\fs18 -0.10 (-1.51, 1.31) \cell +\pard\intbl\qc\fs18 0.17 (-1.05, 1.40) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 140.50 (3.006) \cell +\pard\intbl\qc\fs18 139.91 (2.677) \cell +\pard\intbl\qc\fs18 140.19 (2.836) \cell +\pard\intbl\qc\fs18 140.42 (2.692) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 140.50 (133.0, 145.0) \cell +\pard\intbl\qc\fs18 140.00 (134.0, 145.0) \cell +\pard\intbl\qc\fs18 140.00 (133.0, 145.0) \cell +\pard\intbl\qc\fs18 140.00 (129.0, 144.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 139.88 (2.778) \cell +\pard\intbl\qc\fs18 140.36 (3.145) \cell +\pard\intbl\qc\fs18 140.13 (2.970) \cell +\pard\intbl\qc\fs18 140.24 (2.848) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.62 (3.276) \cell +\pard\intbl\qc\fs18 -0.45 (3.282) \cell +\pard\intbl\qc\fs18 0.06 (3.304) \cell +\pard\intbl\qc\fs18 0.18 (3.092) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.00 (-8.0, 7.0) \cell +\pard\intbl\qc\fs18 -1.00 (-7.0, 5.0) \cell +\pard\intbl\qc\fs18 0.00 (-8.0, 7.0) \cell +\pard\intbl\qc\fs18 0.00 (-9.0, 9.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.44 (-0.87, 1.74) \cell +\pard\intbl\qc\fs18 -0.63 (-1.89, 0.63) \cell +\pard\intbl\qc\fs18 -0.13 (-1.20, 0.95) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Creatinine (umol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 103.05 (18.882) \cell +\pard\intbl\qc\fs18 104.87 (18.290) \cell +\pard\intbl\qc\fs18 103.83 (18.571) \cell +\pard\intbl\qc\fs18 97.10 (16.556) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 106.08 (70.7, 168.0) \cell +\pard\intbl\qc\fs18 106.08 (70.7, 150.3) \cell +\pard\intbl\qc\fs18 106.08 (70.7, 168.0) \cell +\pard\intbl\qc\fs18 97.24 (61.9, 123.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 105.07 (19.641) \cell +\pard\intbl\qc\fs18 108.06 (21.972) \cell +\pard\intbl\qc\fs18 106.40 (20.669) \cell +\pard\intbl\qc\fs18 98.81 (16.286) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 106.08 (70.7, 150.3) \cell +\pard\intbl\qc\fs18 106.08 (61.9, 168.0) \cell +\pard\intbl\qc\fs18 106.08 (61.9, 168.0) \cell +\pard\intbl\qc\fs18 97.24 (70.7, 141.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 103.04 (19.225) \cell +\pard\intbl\qc\fs18 105.36 (18.476) \cell +\pard\intbl\qc\fs18 104.07 (18.844) \cell +\pard\intbl\qc\fs18 97.10 (16.749) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2.03 (9.186) \cell +\pard\intbl\qc\fs18 2.71 (9.583) \cell +\pard\intbl\qc\fs18 2.33 (9.328) \cell +\pard\intbl\qc\fs18 1.71 (7.480) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-17.7, 26.5) \cell +\pard\intbl\qc\fs18 0.00 (-17.7, 26.5) \cell +\pard\intbl\qc\fs18 0.00 (-17.7, 26.5) \cell +\pard\intbl\qc\fs18 0.00 (-17.7, 17.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.32 (-2.68, 3.31) \cell +\pard\intbl\qc\fs18 1.00 (-2.32, 4.31) \cell +\pard\intbl\qc\fs18 0.62 (-1.95, 3.19) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 102.69 (18.112) \cell +\pard\intbl\qc\fs18 106.43 (20.463) \cell +\pard\intbl\qc\fs18 104.64 (19.363) \cell +\pard\intbl\qc\fs18 97.96 (19.048) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 97.24 (70.7, 150.3) \cell +\pard\intbl\qc\fs18 106.08 (70.7, 176.8) \cell +\pard\intbl\qc\fs18 106.08 (70.7, 176.8) \cell +\pard\intbl\qc\fs18 97.24 (70.7, 176.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 101.19 (19.227) \cell +\pard\intbl\qc\fs18 104.87 (18.290) \cell +\pard\intbl\qc\fs18 103.10 (18.739) \cell +\pard\intbl\qc\fs18 96.95 (16.848) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.50 (7.671) \cell +\pard\intbl\qc\fs18 1.56 (10.416) \cell +\pard\intbl\qc\fs18 1.53 (9.156) \cell +\pard\intbl\qc\fs18 1.01 (10.718) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-17.7, 26.5) \cell +\pard\intbl\qc\fs18 0.00 (-26.5, 26.5) \cell +\pard\intbl\qc\fs18 0.00 (-26.5, 26.5) \cell +\pard\intbl\qc\fs18 0.00 (-17.7, 53.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.49 (-3.02, 4.00) \cell +\pard\intbl\qc\fs18 0.55 (-3.42, 4.52) \cell +\pard\intbl\qc\fs18 0.52 (-2.76, 3.80) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 101.03 (17.695) \cell +\pard\intbl\qc\fs18 107.58 (21.442) \cell +\pard\intbl\qc\fs18 104.49 (19.926) \cell +\pard\intbl\qc\fs18 101.10 (18.146) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 97.24 (70.7, 141.4) \cell +\pard\intbl\qc\fs18 106.08 (79.6, 176.8) \cell +\pard\intbl\qc\fs18 97.24 (70.7, 176.8) \cell +\pard\intbl\qc\fs18 97.24 (70.7, 150.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 99.77 (19.552) \cell +\pard\intbl\qc\fs18 105.14 (18.999) \cell +\pard\intbl\qc\fs18 102.60 (19.341) \cell +\pard\intbl\qc\fs18 98.04 (16.164) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.26 (9.479) \cell +\pard\intbl\qc\fs18 2.45 (10.046) \cell +\pard\intbl\qc\fs18 1.89 (9.745) \cell +\pard\intbl\qc\fs18 3.05 (9.352) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-26.5, 26.5) \cell +\pard\intbl\qc\fs18 0.00 (-17.7, 26.5) \cell +\pard\intbl\qc\fs18 0.00 (-26.5, 26.5) \cell +\pard\intbl\qc\fs18 0.00 (-17.7, 35.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -1.79 (-5.63, 2.05) \cell +\pard\intbl\qc\fs18 -0.61 (-4.45, 3.23) \cell +\pard\intbl\qc\fs18 -1.17 (-4.39, 2.06) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Urate (umol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 303.53 (86.697) \cell +\pard\intbl\qc\fs18 308.36 (79.163) \cell +\pard\intbl\qc\fs18 305.62 (83.210) \cell +\pard\intbl\qc\fs18 283.46 (77.886) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 297.40 (136.8, 618.6) \cell +\pard\intbl\qc\fs18 297.40 (172.5, 493.7) \cell +\pard\intbl\qc\fs18 297.40 (136.8, 618.6) \cell +\pard\intbl\qc\fs18 279.56 (136.8, 469.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 306.66 (82.135) \cell +\pard\intbl\qc\fs18 311.97 (78.732) \cell +\pard\intbl\qc\fs18 309.03 (80.313) \cell +\pard\intbl\qc\fs18 284.83 (74.307) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 297.40 (178.4, 541.3) \cell +\pard\intbl\qc\fs18 303.35 (172.5, 499.6) \cell +\pard\intbl\qc\fs18 297.40 (172.5, 541.3) \cell +\pard\intbl\qc\fs18 279.56 (130.9, 475.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 308.81 (87.068) \cell +\pard\intbl\qc\fs18 311.00 (79.634) \cell +\pard\intbl\qc\fs18 309.78 (83.467) \cell +\pard\intbl\qc\fs18 284.45 (78.419) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -2.15 (40.980) \cell +\pard\intbl\qc\fs18 0.97 (35.530) \cell +\pard\intbl\qc\fs18 -0.76 (38.506) \cell +\pard\intbl\qc\fs18 0.38 (43.280) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-119.0, 101.1) \cell +\pard\intbl\qc\fs18 5.95 (-65.4, 101.1) \cell +\pard\intbl\qc\fs18 0.00 (-119.0, 101.1) \cell +\pard\intbl\qc\fs18 5.95 (-154.6, 166.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -2.53 (-17.57, 12.52) \cell +\pard\intbl\qc\fs18 0.59 (-14.24, 15.42) \cell +\pard\intbl\qc\fs18 -1.14 (-14.23, 11.95) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 298.29 (88.005) \cell +\pard\intbl\qc\fs18 301.72 (74.377) \cell +\pard\intbl\qc\fs18 300.07 (80.792) \cell +\pard\intbl\qc\fs18 283.75 (67.376) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 279.56 (124.9, 535.3) \cell +\pard\intbl\qc\fs18 297.40 (154.6, 458.0) \cell +\pard\intbl\qc\fs18 291.45 (124.9, 535.3) \cell +\pard\intbl\qc\fs18 285.50 (148.7, 428.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 301.32 (90.947) \cell +\pard\intbl\qc\fs18 308.36 (79.163) \cell +\pard\intbl\qc\fs18 304.99 (84.648) \cell +\pard\intbl\qc\fs18 284.92 (78.982) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -3.04 (37.718) \cell +\pard\intbl\qc\fs18 -6.65 (45.867) \cell +\pard\intbl\qc\fs18 -4.92 (41.981) \cell +\pard\intbl\qc\fs18 -1.17 (31.713) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -5.95 (-130.9, 77.3) \cell +\pard\intbl\qc\fs18 -17.84 (-148.7, 65.4) \cell +\pard\intbl\qc\fs18 -8.92 (-148.7, 77.3) \cell +\pard\intbl\qc\fs18 0.00 (-107.1, 83.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -1.87 (-15.45, 11.72) \cell +\pard\intbl\qc\fs18 -5.48 (-20.58, 9.63) \cell +\pard\intbl\qc\fs18 -3.75 (-15.35, 7.85) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 291.31 (83.577) \cell +\pard\intbl\qc\fs18 299.42 (72.745) \cell +\pard\intbl\qc\fs18 295.60 (77.700) \cell +\pard\intbl\qc\fs18 288.53 (72.486) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 288.48 (166.5, 559.1) \cell +\pard\intbl\qc\fs18 303.35 (148.7, 481.8) \cell +\pard\intbl\qc\fs18 297.40 (148.7, 559.1) \cell +\pard\intbl\qc\fs18 285.50 (148.7, 422.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 297.82 (86.708) \cell +\pard\intbl\qc\fs18 310.94 (81.269) \cell +\pard\intbl\qc\fs18 304.75 (83.657) \cell +\pard\intbl\qc\fs18 288.75 (78.591) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -6.51 (34.025) \cell +\pard\intbl\qc\fs18 -11.52 (38.335) \cell +\pard\intbl\qc\fs18 -9.16 (36.248) \cell +\pard\intbl\qc\fs18 -0.22 (39.603) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -8.92 (-83.3, 77.3) \cell +\pard\intbl\qc\fs18 -11.90 (-119.0, 59.5) \cell +\pard\intbl\qc\fs18 -11.90 (-119.0, 77.3) \cell +\pard\intbl\qc\fs18 5.95 (-119.0, 77.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -6.30 (-21.17, 8.57) \cell +\pard\intbl\qc\fs18 -11.30 (-26.64, 4.04) \cell +\pard\intbl\qc\fs18 -8.94 (-21.98, 4.10) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alanine Aminotransferase (U/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 17.63 (9.186) \cell +\pard\intbl\qc\fs18 19.49 (10.508) \cell +\pard\intbl\qc\fs18 18.43 (9.780) \cell +\pard\intbl\qc\fs18 17.31 (7.398) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 16.00 (5.0, 70.0) \cell +\pard\intbl\qc\fs18 16.00 (8.0, 62.0) \cell +\pard\intbl\qc\fs18 16.00 (5.0, 70.0) \cell +\pard\intbl\qc\fs18 15.00 (7.0, 50.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 20.49 (11.568) \cell +\pard\intbl\qc\fs18 21.84 (8.688) \cell +\pard\intbl\qc\fs18 21.09 (10.361) \cell +\pard\intbl\qc\fs18 17.93 (13.193) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 18.00 (5.0, 88.0) \cell +\pard\intbl\qc\fs18 19.00 (8.0, 49.0) \cell +\pard\intbl\qc\fs18 19.00 (5.0, 88.0) \cell +\pard\intbl\qc\fs18 15.00 (6.0, 104.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 18.00 (9.518) \cell +\pard\intbl\qc\fs18 19.41 (10.712) \cell +\pard\intbl\qc\fs18 18.63 (10.045) \cell +\pard\intbl\qc\fs18 17.59 (7.469) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2.49 (8.051) \cell +\pard\intbl\qc\fs18 2.43 (7.095) \cell +\pard\intbl\qc\fs18 2.46 (7.606) \cell +\pard\intbl\qc\fs18 0.34 (8.754) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 3.00 (-28.0, 22.0) \cell +\pard\intbl\qc\fs18 3.00 (-31.0, 17.0) \cell +\pard\intbl\qc\fs18 3.00 (-31.0, 22.0) \cell +\pard\intbl\qc\fs18 -1.00 (-14.0, 54.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 2.15 (-0.87, 5.16) \cell +\pard\intbl\qc\fs18 2.08 (-0.91, 5.08) \cell +\pard\intbl\qc\fs18 2.12 (-0.53, 4.76) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 16.55 (8.180) \cell +\pard\intbl\qc\fs18 22.24 (9.981) \cell +\pard\intbl\qc\fs18 19.51 (9.551) \cell +\pard\intbl\qc\fs18 18.07 (13.357) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 15.00 (5.0, 62.0) \cell +\pard\intbl\qc\fs18 21.00 (8.0, 61.0) \cell +\pard\intbl\qc\fs18 18.00 (5.0, 62.0) \cell +\pard\intbl\qc\fs18 15.00 (7.0, 107.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 17.34 (9.626) \cell +\pard\intbl\qc\fs18 19.49 (10.508) \cell +\pard\intbl\qc\fs18 18.46 (10.101) \cell +\pard\intbl\qc\fs18 17.65 (7.521) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.79 (4.496) \cell +\pard\intbl\qc\fs18 2.75 (7.782) \cell +\pard\intbl\qc\fs18 1.05 (6.629) \cell +\pard\intbl\qc\fs18 0.42 (9.069) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-16.0, 12.0) \cell +\pard\intbl\qc\fs18 2.00 (-28.0, 21.0) \cell +\pard\intbl\qc\fs18 1.00 (-28.0, 21.0) \cell +\pard\intbl\qc\fs18 -1.00 (-13.0, 57.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -1.20 (-3.87, 1.46) \cell +\pard\intbl\qc\fs18 2.33 (-0.84, 5.50) \cell +\pard\intbl\qc\fs18 0.63 (-2.04, 3.31) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 15.70 (7.933) \cell +\pard\intbl\qc\fs18 21.70 (10.407) \cell +\pard\intbl\qc\fs18 18.91 (9.760) \cell +\pard\intbl\qc\fs18 17.00 (10.080) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 15.00 (5.0, 57.0) \cell +\pard\intbl\qc\fs18 19.00 (10.0, 60.0) \cell +\pard\intbl\qc\fs18 16.50 (5.0, 60.0) \cell +\pard\intbl\qc\fs18 15.00 (7.0, 76.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 16.90 (9.516) \cell +\pard\intbl\qc\fs18 20.00 (10.853) \cell +\pard\intbl\qc\fs18 18.56 (10.311) \cell +\pard\intbl\qc\fs18 17.15 (6.434) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -1.20 (4.250) \cell +\pard\intbl\qc\fs18 1.70 (5.240) \cell +\pard\intbl\qc\fs18 0.35 (4.994) \cell +\pard\intbl\qc\fs18 -0.15 (7.931) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-13.0, 7.0) \cell +\pard\intbl\qc\fs18 2.00 (-10.0, 15.0) \cell +\pard\intbl\qc\fs18 0.00 (-13.0, 15.0) \cell +\pard\intbl\qc\fs18 -1.00 (-15.0, 46.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -1.05 (-3.59, 1.50) \cell +\pard\intbl\qc\fs18 1.85 (-0.81, 4.50) \cell +\pard\intbl\qc\fs18 0.50 (-1.92, 2.92) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alkaline Phosphatase (U/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 117 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 71.26 (20.269) \cell +\pard\intbl\qc\fs18 74.00 (49.048) \cell +\pard\intbl\qc\fs18 72.45 (35.623) \cell +\pard\intbl\qc\fs18 80.00 (64.873) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 71.00 (31.0, 155.0) \cell +\pard\intbl\qc\fs18 67.00 (33.0, 398.0) \cell +\pard\intbl\qc\fs18 68.00 (31.0, 398.0) \cell +\pard\intbl\qc\fs18 72.50 (28.0, 565.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 71.18 (20.557) \cell +\pard\intbl\qc\fs18 74.67 (49.115) \cell +\pard\intbl\qc\fs18 72.74 (36.027) \cell +\pard\intbl\qc\fs18 78.37 (78.952) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 69.00 (28.0, 131.0) \cell +\pard\intbl\qc\fs18 69.00 (34.0, 390.0) \cell +\pard\intbl\qc\fs18 69.00 (28.0, 390.0) \cell +\pard\intbl\qc\fs18 68.00 (30.0, 672.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 70.98 (20.768) \cell +\pard\intbl\qc\fs18 74.76 (49.906) \cell +\pard\intbl\qc\fs18 72.66 (36.575) \cell +\pard\intbl\qc\fs18 79.90 (65.686) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.20 (10.772) \cell +\pard\intbl\qc\fs18 -0.08 (8.592) \cell +\pard\intbl\qc\fs18 0.07 (9.818) \cell +\pard\intbl\qc\fs18 -1.21 (16.828) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-24.0, 44.0) \cell +\pard\intbl\qc\fs18 -2.00 (-18.0, 24.0) \cell +\pard\intbl\qc\fs18 -2.00 (-24.0, 44.0) \cell +\pard\intbl\qc\fs18 -3.00 (-39.0, 107.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 1.41 (-3.64, 6.45) \cell +\pard\intbl\qc\fs18 1.13 (-3.76, 6.02) \cell +\pard\intbl\qc\fs18 1.28 (-3.36, 5.92) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 72.26 (22.407) \cell +\pard\intbl\qc\fs18 73.37 (47.031) \cell +\pard\intbl\qc\fs18 72.84 (37.129) \cell +\pard\intbl\qc\fs18 79.31 (77.559) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 71.00 (26.0, 136.0) \cell +\pard\intbl\qc\fs18 66.00 (34.0, 382.0) \cell +\pard\intbl\qc\fs18 67.00 (26.0, 382.0) \cell +\pard\intbl\qc\fs18 69.00 (30.0, 657.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 97 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 72.26 (22.334) \cell +\pard\intbl\qc\fs18 74.00 (49.048) \cell +\pard\intbl\qc\fs18 73.18 (38.569) \cell +\pard\intbl\qc\fs18 80.10 (66.213) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.57 (10.821) \cell +\pard\intbl\qc\fs18 -0.63 (6.980) \cell +\pard\intbl\qc\fs18 -0.06 (8.979) \cell +\pard\intbl\qc\fs18 -0.61 (15.102) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-21.0, 34.0) \cell +\pard\intbl\qc\fs18 -2.00 (-16.0, 13.0) \cell +\pard\intbl\qc\fs18 -1.00 (-21.0, 34.0) \cell +\pard\intbl\qc\fs18 0.00 (-30.0, 92.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 1.17 (-3.80, 6.14) \cell +\pard\intbl\qc\fs18 -0.02 (-4.33, 4.28) \cell +\pard\intbl\qc\fs18 0.54 (-3.70, 4.79) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 71.69 (23.604) \cell +\pard\intbl\qc\fs18 74.68 (50.572) \cell +\pard\intbl\qc\fs18 73.27 (39.984) \cell +\pard\intbl\qc\fs18 68.55 (20.877) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 68.50 (32.0, 137.0) \cell +\pard\intbl\qc\fs18 65.00 (29.0, 378.0) \cell +\pard\intbl\qc\fs18 67.00 (29.0, 378.0) \cell +\pard\intbl\qc\fs18 66.00 (29.0, 150.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 72.31 (22.660) \cell +\pard\intbl\qc\fs18 74.23 (51.085) \cell +\pard\intbl\qc\fs18 73.33 (40.054) \cell +\pard\intbl\qc\fs18 70.40 (20.197) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.62 (11.111) \cell +\pard\intbl\qc\fs18 0.45 (14.627) \cell +\pard\intbl\qc\fs18 -0.06 (13.025) \cell +\pard\intbl\qc\fs18 -1.62 (9.776) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.50 (-31.0, 37.0) \cell +\pard\intbl\qc\fs18 -2.00 (-21.0, 58.0) \cell +\pard\intbl\qc\fs18 -2.00 (-31.0, 58.0) \cell +\pard\intbl\qc\fs18 -1.00 (-30.0, 23.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 1.00 (-3.30, 5.30) \cell +\pard\intbl\qc\fs18 2.06 (-2.93, 7.06) \cell +\pard\intbl\qc\fs18 1.56 (-2.21, 5.34) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Aspartate Aminotransferase (U/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 22.48 (8.188) \cell +\pard\intbl\qc\fs18 23.45 (6.706) \cell +\pard\intbl\qc\fs18 22.90 (7.568) \cell +\pard\intbl\qc\fs18 23.19 (6.730) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 20.00 (13.0, 60.0) \cell +\pard\intbl\qc\fs18 23.00 (14.0, 52.0) \cell +\pard\intbl\qc\fs18 21.00 (13.0, 60.0) \cell +\pard\intbl\qc\fs18 23.00 (13.0, 54.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 24.03 (8.214) \cell +\pard\intbl\qc\fs18 23.80 (4.835) \cell +\pard\intbl\qc\fs18 23.93 (6.888) \cell +\pard\intbl\qc\fs18 23.69 (13.611) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 23.00 (10.0, 62.0) \cell +\pard\intbl\qc\fs18 23.00 (15.0, 37.0) \cell +\pard\intbl\qc\fs18 23.00 (10.0, 62.0) \cell +\pard\intbl\qc\fs18 21.00 (13.0, 118.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 22.30 (6.888) \cell +\pard\intbl\qc\fs18 23.35 (6.821) \cell +\pard\intbl\qc\fs18 22.76 (6.847) \cell +\pard\intbl\qc\fs18 23.38 (6.815) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.74 (6.608) \cell +\pard\intbl\qc\fs18 0.45 (5.331) \cell +\pard\intbl\qc\fs18 1.16 (6.080) \cell +\pard\intbl\qc\fs18 0.31 (9.782) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 2.00 (-30.0, 18.0) \cell +\pard\intbl\qc\fs18 1.00 (-22.0, 9.0) \cell +\pard\intbl\qc\fs18 2.00 (-30.0, 18.0) \cell +\pard\intbl\qc\fs18 -1.00 (-10.0, 64.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 1.43 (-1.57, 4.42) \cell +\pard\intbl\qc\fs18 0.14 (-2.77, 3.05) \cell +\pard\intbl\qc\fs18 0.85 (-1.89, 3.60) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 20.96 (5.544) \cell +\pard\intbl\qc\fs18 24.41 (5.947) \cell +\pard\intbl\qc\fs18 22.76 (5.985) \cell +\pard\intbl\qc\fs18 23.30 (15.366) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 20.00 (13.0, 46.0) \cell +\pard\intbl\qc\fs18 24.00 (15.0, 43.0) \cell +\pard\intbl\qc\fs18 21.00 (13.0, 46.0) \cell +\pard\intbl\qc\fs18 21.00 (12.0, 135.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 22.60 (9.050) \cell +\pard\intbl\qc\fs18 23.45 (6.706) \cell +\pard\intbl\qc\fs18 23.04 (7.887) \cell +\pard\intbl\qc\fs18 23.28 (6.860) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -1.64 (6.654) \cell +\pard\intbl\qc\fs18 0.96 (5.553) \cell +\pard\intbl\qc\fs18 -0.29 (6.213) \cell +\pard\intbl\qc\fs18 0.02 (11.647) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-39.0, 5.0) \cell +\pard\intbl\qc\fs18 1.00 (-22.0, 13.0) \cell +\pard\intbl\qc\fs18 0.00 (-39.0, 13.0) \cell +\pard\intbl\qc\fs18 -1.00 (-19.0, 81.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -1.65 (-5.21, 1.90) \cell +\pard\intbl\qc\fs18 0.94 (-2.42, 4.31) \cell +\pard\intbl\qc\fs18 -0.30 (-3.54, 2.94) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 21.03 (5.933) \cell +\pard\intbl\qc\fs18 24.65 (8.769) \cell +\pard\intbl\qc\fs18 22.97 (7.757) \cell +\pard\intbl\qc\fs18 22.30 (6.916) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 20.00 (9.0, 48.0) \cell +\pard\intbl\qc\fs18 23.00 (16.0, 73.0) \cell +\pard\intbl\qc\fs18 22.00 (9.0, 73.0) \cell +\pard\intbl\qc\fs18 22.00 (14.0, 58.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 21.13 (6.098) \cell +\pard\intbl\qc\fs18 23.87 (6.892) \cell +\pard\intbl\qc\fs18 22.59 (6.641) \cell +\pard\intbl\qc\fs18 22.96 (5.821) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.10 (3.193) \cell +\pard\intbl\qc\fs18 0.78 (5.015) \cell +\pard\intbl\qc\fs18 0.37 (4.265) \cell +\pard\intbl\qc\fs18 -0.66 (6.145) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-8.0, 6.0) \cell +\pard\intbl\qc\fs18 0.00 (-7.0, 21.0) \cell +\pard\intbl\qc\fs18 0.00 (-8.0, 21.0) \cell +\pard\intbl\qc\fs18 -1.00 (-14.0, 31.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.56 (-1.40, 2.52) \cell +\pard\intbl\qc\fs18 1.44 (-0.78, 3.67) \cell +\pard\intbl\qc\fs18 1.03 (-0.88, 2.94) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Bilirubin (umol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 9.32 (3.941) \cell +\pard\intbl\qc\fs18 11.06 (5.539) \cell +\pard\intbl\qc\fs18 10.07 (4.757) \cell +\pard\intbl\qc\fs18 9.43 (3.890) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 22.2) \cell +\pard\intbl\qc\fs18 10.26 (3.4, 34.2) \cell +\pard\intbl\qc\fs18 8.55 (3.4, 34.2) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 25.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 9.36 (4.066) \cell +\pard\intbl\qc\fs18 10.26 (3.824) \cell +\pard\intbl\qc\fs18 9.76 (3.967) \cell +\pard\intbl\qc\fs18 11.07 (14.158) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 25.7) \cell +\pard\intbl\qc\fs18 10.26 (5.1, 23.9) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 25.7) \cell +\pard\intbl\qc\fs18 8.55 (3.4, 116.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 9.39 (4.006) \cell +\pard\intbl\qc\fs18 10.96 (5.617) \cell +\pard\intbl\qc\fs18 10.09 (4.831) \cell +\pard\intbl\qc\fs18 9.56 (3.929) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.03 (2.904) \cell +\pard\intbl\qc\fs18 -0.70 (3.347) \cell +\pard\intbl\qc\fs18 -0.33 (3.112) \cell +\pard\intbl\qc\fs18 1.51 (11.872) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-8.6, 6.8) \cell +\pard\intbl\qc\fs18 0.00 (-15.4, 5.1) \cell +\pard\intbl\qc\fs18 0.00 (-15.4, 6.8) \cell +\pard\intbl\qc\fs18 0.00 (-6.8, 90.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -1.54 (-4.67, 1.58) \cell +\pard\intbl\qc\fs18 -2.21 (-5.39, 0.97) \cell +\pard\intbl\qc\fs18 -1.84 (-4.93, 1.25) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 97 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 9.48 (3.741) \cell +\pard\intbl\qc\fs18 10.76 (5.867) \cell +\pard\intbl\qc\fs18 10.15 (4.990) \cell +\pard\intbl\qc\fs18 11.60 (15.463) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 22.2) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 34.2) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 34.2) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 124.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 97 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 9.74 (4.384) \cell +\pard\intbl\qc\fs18 11.06 (5.539) \cell +\pard\intbl\qc\fs18 10.44 (5.043) \cell +\pard\intbl\qc\fs18 9.58 (3.972) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.26 (2.006) \cell +\pard\intbl\qc\fs18 -0.30 (2.916) \cell +\pard\intbl\qc\fs18 -0.28 (2.513) \cell +\pard\intbl\qc\fs18 2.02 (13.165) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-5.1, 3.4) \cell +\pard\intbl\qc\fs18 0.00 (-5.1, 6.8) \cell +\pard\intbl\qc\fs18 0.00 (-5.1, 6.8) \cell +\pard\intbl\qc\fs18 0.00 (-5.1, 99.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -2.28 (-5.73, 1.16) \cell +\pard\intbl\qc\fs18 -2.33 (-5.82, 1.16) \cell +\pard\intbl\qc\fs18 -2.31 (-5.74, 1.13) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 9.28 (4.078) \cell +\pard\intbl\qc\fs18 10.85 (5.024) \cell +\pard\intbl\qc\fs18 10.12 (4.650) \cell +\pard\intbl\qc\fs18 9.87 (4.116) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 23.9) \cell +\pard\intbl\qc\fs18 10.26 (5.1, 29.1) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 29.1) \cell +\pard\intbl\qc\fs18 8.55 (5.1, 22.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 9.66 (4.016) \cell +\pard\intbl\qc\fs18 11.49 (5.627) \cell +\pard\intbl\qc\fs18 10.64 (5.000) \cell +\pard\intbl\qc\fs18 9.45 (3.463) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.38 (2.207) \cell +\pard\intbl\qc\fs18 -0.63 (3.088) \cell +\pard\intbl\qc\fs18 -0.52 (2.701) \cell +\pard\intbl\qc\fs18 0.42 (3.072) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-6.8, 5.1) \cell +\pard\intbl\qc\fs18 -1.71 (-8.6, 5.1) \cell +\pard\intbl\qc\fs18 0.00 (-8.6, 5.1) \cell +\pard\intbl\qc\fs18 0.00 (-5.1, 12.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -0.80 (-1.89, 0.28) \cell +\pard\intbl\qc\fs18 -1.05 (-2.28, 0.18) \cell +\pard\intbl\qc\fs18 -0.94 (-1.95, 0.08) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gamma Glutamyl Transferase (U/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 21.36 (13.438) \cell +\pard\intbl\qc\fs18 24.65 (21.424) \cell +\pard\intbl\qc\fs18 22.78 (17.340) \cell +\pard\intbl\qc\fs18 25.95 (56.947) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 19.00 (6.0, 89.0) \cell +\pard\intbl\qc\fs18 18.00 (9.0, 120.0) \cell +\pard\intbl\qc\fs18 19.00 (6.0, 120.0) \cell +\pard\intbl\qc\fs18 16.00 (8.0, 466.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 21.92 (14.322) \cell +\pard\intbl\qc\fs18 25.20 (20.790) \cell +\pard\intbl\qc\fs18 23.38 (17.491) \cell +\pard\intbl\qc\fs18 25.11 (54.141) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 18.00 (7.0, 92.0) \cell +\pard\intbl\qc\fs18 18.00 (9.0, 128.0) \cell +\pard\intbl\qc\fs18 18.00 (7.0, 128.0) \cell +\pard\intbl\qc\fs18 16.00 (8.0, 438.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 21.74 (13.870) \cell +\pard\intbl\qc\fs18 25.04 (21.773) \cell +\pard\intbl\qc\fs18 23.21 (17.815) \cell +\pard\intbl\qc\fs18 26.16 (57.861) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.18 (10.259) \cell +\pard\intbl\qc\fs18 0.16 (11.435) \cell +\pard\intbl\qc\fs18 0.17 (10.748) \cell +\pard\intbl\qc\fs18 -1.05 (5.496) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-53.0, 31.0) \cell +\pard\intbl\qc\fs18 -1.00 (-48.0, 58.0) \cell +\pard\intbl\qc\fs18 0.00 (-53.0, 58.0) \cell +\pard\intbl\qc\fs18 -1.00 (-28.0, 10.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 1.23 (-1.73, 4.18) \cell +\pard\intbl\qc\fs18 1.21 (-2.34, 4.76) \cell +\pard\intbl\qc\fs18 1.22 (-1.23, 3.67) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 21.70 (12.237) \cell +\pard\intbl\qc\fs18 24.29 (17.651) \cell +\pard\intbl\qc\fs18 23.05 (15.274) \cell +\pard\intbl\qc\fs18 25.18 (55.649) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 19.00 (7.0, 64.0) \cell +\pard\intbl\qc\fs18 18.00 (10.0, 114.0) \cell +\pard\intbl\qc\fs18 19.00 (7.0, 114.0) \cell +\pard\intbl\qc\fs18 16.00 (9.0, 447.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 22.81 (15.410) \cell +\pard\intbl\qc\fs18 24.65 (21.424) \cell +\pard\intbl\qc\fs18 23.77 (18.710) \cell +\pard\intbl\qc\fs18 26.39 (58.312) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -1.11 (8.388) \cell +\pard\intbl\qc\fs18 -0.35 (11.036) \cell +\pard\intbl\qc\fs18 -0.71 (9.813) \cell +\pard\intbl\qc\fs18 -1.21 (6.056) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-47.0, 14.0) \cell +\pard\intbl\qc\fs18 0.00 (-62.0, 28.0) \cell +\pard\intbl\qc\fs18 0.00 (-62.0, 28.0) \cell +\pard\intbl\qc\fs18 0.00 (-34.0, 9.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.11 (-2.78, 2.99) \cell +\pard\intbl\qc\fs18 0.86 (-2.58, 4.30) \cell +\pard\intbl\qc\fs18 0.50 (-1.99, 2.98) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 21.07 (11.031) \cell +\pard\intbl\qc\fs18 22.21 (14.810) \cell +\pard\intbl\qc\fs18 21.67 (13.103) \cell +\pard\intbl\qc\fs18 19.84 (16.353) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 17.50 (7.0, 57.0) \cell +\pard\intbl\qc\fs18 18.00 (7.0, 98.0) \cell +\pard\intbl\qc\fs18 18.00 (7.0, 98.0) \cell +\pard\intbl\qc\fs18 16.00 (7.0, 119.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 22.12 (12.160) \cell +\pard\intbl\qc\fs18 23.06 (18.134) \cell +\pard\intbl\qc\fs18 22.62 (15.525) \cell +\pard\intbl\qc\fs18 19.49 (11.678) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -1.05 (5.123) \cell +\pard\intbl\qc\fs18 -0.85 (7.579) \cell +\pard\intbl\qc\fs18 -0.94 (6.501) \cell +\pard\intbl\qc\fs18 0.35 (6.441) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.00 (-23.0, 10.0) \cell +\pard\intbl\qc\fs18 0.00 (-24.0, 16.0) \cell +\pard\intbl\qc\fs18 0.00 (-24.0, 16.0) \cell +\pard\intbl\qc\fs18 0.00 (-14.0, 39.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -1.39 (-3.72, 0.94) \cell +\pard\intbl\qc\fs18 -1.20 (-3.99, 1.60) \cell +\pard\intbl\qc\fs18 -1.29 (-3.49, 0.91) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.66 (0.870) \cell +\pard\intbl\qc\fs18 5.94 (1.018) \cell +\pard\intbl\qc\fs18 5.78 (0.943) \cell +\pard\intbl\qc\fs18 5.80 (0.973) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 5.61 (3.7, 7.7) \cell +\pard\intbl\qc\fs18 5.97 (4.0, 8.0) \cell +\pard\intbl\qc\fs18 5.68 (3.7, 8.0) \cell +\pard\intbl\qc\fs18 5.72 (3.7, 8.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.57 (0.896) \cell +\pard\intbl\qc\fs18 5.67 (0.922) \cell +\pard\intbl\qc\fs18 5.61 (0.905) \cell +\pard\intbl\qc\fs18 5.58 (0.917) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 5.46 (3.6, 8.1) \cell +\pard\intbl\qc\fs18 5.66 (4.0, 7.6) \cell +\pard\intbl\qc\fs18 5.59 (3.6, 8.1) \cell +\pard\intbl\qc\fs18 5.46 (3.7, 7.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 5.67 (0.867) \cell +\pard\intbl\qc\fs18 5.96 (1.035) \cell +\pard\intbl\qc\fs18 5.80 (0.953) \cell +\pard\intbl\qc\fs18 5.77 (0.941) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.09 (0.511) \cell +\pard\intbl\qc\fs18 -0.29 (0.542) \cell +\pard\intbl\qc\fs18 -0.18 (0.532) \cell +\pard\intbl\qc\fs18 -0.19 (0.408) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.08 (-1.4, 1.0) \cell +\pard\intbl\qc\fs18 -0.26 (-1.8, 0.7) \cell +\pard\intbl\qc\fs18 -0.16 (-1.8, 1.0) \cell +\pard\intbl\qc\fs18 -0.12 (-1.2, 0.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.10 (-0.06, 0.27) \cell +\pard\intbl\qc\fs18 -0.10 (-0.28, 0.09) \cell +\pard\intbl\qc\fs18 0.01 (-0.13, 0.16) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.57 (0.896) \cell +\pard\intbl\qc\fs18 5.62 (0.936) \cell +\pard\intbl\qc\fs18 5.59 (0.912) \cell +\pard\intbl\qc\fs18 5.53 (0.875) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 5.46 (4.1, 7.8) \cell +\pard\intbl\qc\fs18 5.64 (3.7, 7.3) \cell +\pard\intbl\qc\fs18 5.55 (3.7, 7.8) \cell +\pard\intbl\qc\fs18 5.56 (3.5, 8.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 5.67 (0.888) \cell +\pard\intbl\qc\fs18 5.94 (1.018) \cell +\pard\intbl\qc\fs18 5.81 (0.963) \cell +\pard\intbl\qc\fs18 5.78 (0.946) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.10 (0.401) \cell +\pard\intbl\qc\fs18 -0.32 (0.503) \cell +\pard\intbl\qc\fs18 -0.22 (0.468) \cell +\pard\intbl\qc\fs18 -0.25 (0.555) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.08 (-1.3, 0.5) \cell +\pard\intbl\qc\fs18 -0.34 (-1.5, 0.7) \cell +\pard\intbl\qc\fs18 -0.18 (-1.5, 0.7) \cell +\pard\intbl\qc\fs18 -0.23 (-2.0, 0.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.15 (-0.04, 0.33) \cell +\pard\intbl\qc\fs18 -0.07 (-0.27, 0.13) \cell +\pard\intbl\qc\fs18 0.03 (-0.14, 0.20) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 5.52 (0.993) \cell +\pard\intbl\qc\fs18 5.59 (0.851) \cell +\pard\intbl\qc\fs18 5.55 (0.916) \cell +\pard\intbl\qc\fs18 5.53 (0.850) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 5.42 (4.1, 7.9) \cell +\pard\intbl\qc\fs18 5.77 (3.7, 7.4) \cell +\pard\intbl\qc\fs18 5.56 (3.7, 7.9) \cell +\pard\intbl\qc\fs18 5.40 (3.7, 7.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 5.65 (0.880) \cell +\pard\intbl\qc\fs18 5.99 (0.986) \cell +\pard\intbl\qc\fs18 5.83 (0.948) \cell +\pard\intbl\qc\fs18 5.71 (0.913) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.13 (0.461) \cell +\pard\intbl\qc\fs18 -0.40 (0.647) \cell +\pard\intbl\qc\fs18 -0.27 (0.581) \cell +\pard\intbl\qc\fs18 -0.18 (0.545) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.10 (-1.4, 1.2) \cell +\pard\intbl\qc\fs18 -0.47 (-1.9, 1.0) \cell +\pard\intbl\qc\fs18 -0.26 (-1.9, 1.2) \cell +\pard\intbl\qc\fs18 -0.13 (-1.3, 1.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.05 (-0.15, 0.25) \cell +\pard\intbl\qc\fs18 -0.22 (-0.46, 0.01) \cell +\pard\intbl\qc\fs18 -0.09 (-0.28, 0.10) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HDL Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 116 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.59 (0.487) \cell +\pard\intbl\qc\fs18 1.64 (0.528) \cell +\pard\intbl\qc\fs18 1.61 (0.503) \cell +\pard\intbl\qc\fs18 1.63 (0.535) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.52 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.60 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.58 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.57 (0.8, 2.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 112 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.63 (0.546) \cell +\pard\intbl\qc\fs18 1.73 (0.480) \cell +\pard\intbl\qc\fs18 1.68 (0.517) \cell +\pard\intbl\qc\fs18 1.59 (0.555) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.68 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.85 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.71 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.48 (0.8, 2.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 105 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 1.56 (0.487) \cell +\pard\intbl\qc\fs18 1.63 (0.539) \cell +\pard\intbl\qc\fs18 1.59 (0.510) \cell +\pard\intbl\qc\fs18 1.62 (0.543) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.08 (0.756) \cell +\pard\intbl\qc\fs18 0.09 (0.750) \cell +\pard\intbl\qc\fs18 0.08 (0.749) \cell +\pard\intbl\qc\fs18 -0.03 (0.834) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.09 (-1.4, 1.5) \cell +\pard\intbl\qc\fs18 0.06 (-1.6, 1.6) \cell +\pard\intbl\qc\fs18 0.08 (-1.6, 1.6) \cell +\pard\intbl\qc\fs18 0.12 (-1.6, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.11 (-0.18, 0.41) \cell +\pard\intbl\qc\fs18 0.12 (-0.19, 0.43) \cell +\pard\intbl\qc\fs18 0.12 (-0.15, 0.38) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 93 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.63 (0.515) \cell +\pard\intbl\qc\fs18 1.66 (0.494) \cell +\pard\intbl\qc\fs18 1.64 (0.502) \cell +\pard\intbl\qc\fs18 1.58 (0.537) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.60 (0.8, 2.4) \cell +\pard\intbl\qc\fs18 1.76 (0.8, 2.4) \cell +\pard\intbl\qc\fs18 1.65 (0.8, 2.4) \cell +\pard\intbl\qc\fs18 1.68 (0.8, 2.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 87 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 1.62 (0.462) \cell +\pard\intbl\qc\fs18 1.65 (0.538) \cell +\pard\intbl\qc\fs18 1.64 (0.500) \cell +\pard\intbl\qc\fs18 1.62 (0.550) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.00 (0.775) \cell +\pard\intbl\qc\fs18 0.03 (0.653) \cell +\pard\intbl\qc\fs18 0.02 (0.710) \cell +\pard\intbl\qc\fs18 -0.05 (0.884) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.01 (-1.6, 1.6) \cell +\pard\intbl\qc\fs18 0.07 (-1.6, 1.2) \cell +\pard\intbl\qc\fs18 0.05 (-1.6, 1.6) \cell +\pard\intbl\qc\fs18 0.00 (-1.7, 1.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.05 (-0.29, 0.39) \cell +\pard\intbl\qc\fs18 0.08 (-0.22, 0.39) \cell +\pard\intbl\qc\fs18 0.07 (-0.21, 0.35) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 84 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.74 (0.482) \cell +\pard\intbl\qc\fs18 1.66 (0.526) \cell +\pard\intbl\qc\fs18 1.70 (0.504) \cell +\pard\intbl\qc\fs18 1.67 (0.498) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.64 (0.9, 2.4) \cell +\pard\intbl\qc\fs18 1.71 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.68 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.64 (0.8, 2.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 1.65 (0.454) \cell +\pard\intbl\qc\fs18 1.62 (0.556) \cell +\pard\intbl\qc\fs18 1.63 (0.508) \cell +\pard\intbl\qc\fs18 1.61 (0.533) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.09 (0.628) \cell +\pard\intbl\qc\fs18 0.03 (0.682) \cell +\pard\intbl\qc\fs18 0.06 (0.654) \cell +\pard\intbl\qc\fs18 0.06 (0.685) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.08 (-1.1, 1.6) \cell +\pard\intbl\qc\fs18 -0.01 (-1.3, 1.7) \cell +\pard\intbl\qc\fs18 0.04 (-1.3, 1.7) \cell +\pard\intbl\qc\fs18 0.11 (-1.5, 1.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.03 (-0.26, 0.31) \cell +\pard\intbl\qc\fs18 -0.03 (-0.32, 0.25) \cell +\pard\intbl\qc\fs18 -0.01 (-0.25, 0.24) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 LDL Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.50 (0.499) \cell +\pard\intbl\qc\fs18 1.61 (0.454) \cell +\pard\intbl\qc\fs18 1.54 (0.482) \cell +\pard\intbl\qc\fs18 1.67 (0.534) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.40 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.73 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.44 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.72 (0.9, 2.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.70 (0.542) \cell +\pard\intbl\qc\fs18 1.57 (0.478) \cell +\pard\intbl\qc\fs18 1.64 (0.516) \cell +\pard\intbl\qc\fs18 1.61 (0.543) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.80 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.57 (0.8, 2.4) \cell +\pard\intbl\qc\fs18 1.66 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.52 (0.8, 2.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 102 \cell +\pard\intbl\qc\fs18 54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 1.45 (0.492) \cell +\pard\intbl\qc\fs18 1.62 (0.463) \cell +\pard\intbl\qc\fs18 1.52 (0.484) \cell +\pard\intbl\qc\fs18 1.73 (0.513) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.27 (0.751) \cell +\pard\intbl\qc\fs18 -0.03 (0.676) \cell +\pard\intbl\qc\fs18 0.14 (0.731) \cell +\pard\intbl\qc\fs18 -0.14 (0.746) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.26 (-1.6, 1.6) \cell +\pard\intbl\qc\fs18 -0.02 (-1.7, 1.5) \cell +\pard\intbl\qc\fs18 0.11 (-1.7, 1.6) \cell +\pard\intbl\qc\fs18 -0.05 (-1.6, 1.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.41 (0.13, 0.69) \cell +\pard\intbl\qc\fs18 0.12 (-0.17, 0.40) \cell +\pard\intbl\qc\fs18 0.28 (0.03, 0.53) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.62 (0.535) \cell +\pard\intbl\qc\fs18 1.55 (0.518) \cell +\pard\intbl\qc\fs18 1.59 (0.525) \cell +\pard\intbl\qc\fs18 1.66 (0.528) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.78 (0.8, 2.4) \cell +\pard\intbl\qc\fs18 1.44 (0.8, 2.4) \cell +\pard\intbl\qc\fs18 1.64 (0.8, 2.4) \cell +\pard\intbl\qc\fs18 1.59 (0.8, 2.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 90 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 1.49 (0.524) \cell +\pard\intbl\qc\fs18 1.59 (0.468) \cell +\pard\intbl\qc\fs18 1.55 (0.496) \cell +\pard\intbl\qc\fs18 1.74 (0.515) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.11 (0.623) \cell +\pard\intbl\qc\fs18 -0.06 (0.662) \cell +\pard\intbl\qc\fs18 0.02 (0.646) \cell +\pard\intbl\qc\fs18 -0.05 (0.678) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.04 (-1.1, 1.3) \cell +\pard\intbl\qc\fs18 -0.04 (-1.5, 1.4) \cell +\pard\intbl\qc\fs18 0.01 (-1.5, 1.4) \cell +\pard\intbl\qc\fs18 0.03 (-1.2, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.16 (-0.11, 0.42) \cell +\pard\intbl\qc\fs18 -0.01 (-0.28, 0.25) \cell +\pard\intbl\qc\fs18 0.07 (-0.16, 0.30) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 1.56 (0.534) \cell +\pard\intbl\qc\fs18 1.60 (0.531) \cell +\pard\intbl\qc\fs18 1.58 (0.530) \cell +\pard\intbl\qc\fs18 1.75 (0.515) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 1.52 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.62 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.56 (0.8, 2.5) \cell +\pard\intbl\qc\fs18 1.78 (0.8, 2.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 83 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 1.48 (0.544) \cell +\pard\intbl\qc\fs18 1.60 (0.456) \cell +\pard\intbl\qc\fs18 1.54 (0.500) \cell +\pard\intbl\qc\fs18 1.71 (0.517) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.08 (0.573) \cell +\pard\intbl\qc\fs18 0.00 (0.695) \cell +\pard\intbl\qc\fs18 0.04 (0.638) \cell +\pard\intbl\qc\fs18 0.07 (0.718) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.05 (-1.1, 1.5) \cell +\pard\intbl\qc\fs18 0.01 (-1.5, 1.6) \cell +\pard\intbl\qc\fs18 0.05 (-1.5, 1.6) \cell +\pard\intbl\qc\fs18 -0.09 (-1.4, 1.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.01 (-0.27, 0.28) \cell +\pard\intbl\qc\fs18 -0.07 (-0.36, 0.23) \cell +\pard\intbl\qc\fs18 -0.03 (-0.28, 0.22) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Triglycerides (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2.40 (1.499) \cell +\pard\intbl\qc\fs18 2.74 (1.328) \cell +\pard\intbl\qc\fs18 2.54 (1.431) \cell +\pard\intbl\qc\fs18 2.49 (1.534) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 2.31 (0.1, 5.0) \cell +\pard\intbl\qc\fs18 2.50 (0.4, 5.0) \cell +\pard\intbl\qc\fs18 2.41 (0.1, 5.0) \cell +\pard\intbl\qc\fs18 2.24 (0.1, 5.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 112 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2.43 (1.483) \cell +\pard\intbl\qc\fs18 2.36 (1.412) \cell +\pard\intbl\qc\fs18 2.40 (1.445) \cell +\pard\intbl\qc\fs18 2.58 (1.448) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 2.48 (0.1, 4.9) \cell +\pard\intbl\qc\fs18 2.34 (0.2, 4.9) \cell +\pard\intbl\qc\fs18 2.39 (0.1, 4.9) \cell +\pard\intbl\qc\fs18 2.69 (0.1, 4.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 106 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 2.47 (1.524) \cell +\pard\intbl\qc\fs18 2.74 (1.366) \cell +\pard\intbl\qc\fs18 2.59 (1.454) \cell +\pard\intbl\qc\fs18 2.48 (1.567) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.04 (2.022) \cell +\pard\intbl\qc\fs18 -0.44 (1.950) \cell +\pard\intbl\qc\fs18 -0.22 (1.990) \cell +\pard\intbl\qc\fs18 0.12 (2.500) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.11 (-4.0, 4.1) \cell +\pard\intbl\qc\fs18 -0.49 (-4.6, 3.4) \cell +\pard\intbl\qc\fs18 -0.26 (-4.6, 4.1) \cell +\pard\intbl\qc\fs18 0.77 (-4.8, 3.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -0.16 (-1.00, 0.68) \cell +\pard\intbl\qc\fs18 -0.57 (-1.43, 0.29) \cell +\pard\intbl\qc\fs18 -0.35 (-1.11, 0.42) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 96 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2.35 (1.192) \cell +\pard\intbl\qc\fs18 2.71 (1.466) \cell +\pard\intbl\qc\fs18 2.54 (1.347) \cell +\pard\intbl\qc\fs18 2.28 (1.398) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 2.28 (0.2, 4.7) \cell +\pard\intbl\qc\fs18 2.53 (0.2, 5.0) \cell +\pard\intbl\qc\fs18 2.40 (0.2, 5.0) \cell +\pard\intbl\qc\fs18 2.13 (0.1, 4.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 2.50 (1.518) \cell +\pard\intbl\qc\fs18 2.76 (1.374) \cell +\pard\intbl\qc\fs18 2.64 (1.441) \cell +\pard\intbl\qc\fs18 2.48 (1.574) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.17 (1.909) \cell +\pard\intbl\qc\fs18 -0.05 (2.115) \cell +\pard\intbl\qc\fs18 -0.11 (2.010) \cell +\pard\intbl\qc\fs18 -0.17 (2.103) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.00 (-4.1, 4.3) \cell +\pard\intbl\qc\fs18 -0.09 (-4.7, 4.3) \cell +\pard\intbl\qc\fs18 -0.09 (-4.7, 4.3) \cell +\pard\intbl\qc\fs18 -0.20 (-4.6, 4.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.00 (-0.81, 0.81) \cell +\pard\intbl\qc\fs18 0.12 (-0.71, 0.95) \cell +\pard\intbl\qc\fs18 0.06 (-0.64, 0.77) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 85 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2.21 (1.402) \cell +\pard\intbl\qc\fs18 2.43 (1.487) \cell +\pard\intbl\qc\fs18 2.33 (1.443) \cell +\pard\intbl\qc\fs18 2.56 (1.365) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 2.12 (0.3, 4.9) \cell +\pard\intbl\qc\fs18 2.71 (0.1, 4.9) \cell +\pard\intbl\qc\fs18 2.24 (0.1, 4.9) \cell +\pard\intbl\qc\fs18 2.53 (0.1, 5.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 2.57 (1.571) \cell +\pard\intbl\qc\fs18 2.67 (1.362) \cell +\pard\intbl\qc\fs18 2.62 (1.453) \cell +\pard\intbl\qc\fs18 2.48 (1.606) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.28 (2.212) \cell +\pard\intbl\qc\fs18 -0.24 (1.958) \cell +\pard\intbl\qc\fs18 -0.26 (2.065) \cell +\pard\intbl\qc\fs18 0.09 (2.309) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.20 (-4.6, 4.1) \cell +\pard\intbl\qc\fs18 -0.32 (-4.0, 4.1) \cell +\pard\intbl\qc\fs18 -0.24 (-4.6, 4.1) \cell +\pard\intbl\qc\fs18 -0.15 (-4.6, 4.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2853 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5366 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7879 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10392 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 -0.37 (-1.35, 0.61) \cell +\pard\intbl\qc\fs18 -0.34 (-1.22, 0.55) \cell +\pard\intbl\qc\fs18 -0.35 (-1.15, 0.45) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2853 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5366 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7879 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10392 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2853 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5366 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7879 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10392 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab01part1/tsflab01part1of2.rtf b/tests/testthat/_snaps/tsflab01part1/tsflab01part1of2.rtf deleted file mode 100644 index 6209708a..00000000 --- a/tests/testthat/_snaps/tsflab01part1/tsflab01part1of2.rtf +++ /dev/null @@ -1,544 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2846 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3993 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5777 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7774 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8921 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10705 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB01part1of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2846 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3993 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5777 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7774 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8921 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10705 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx3993 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx5777 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx7774 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx8921 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx10705 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadft3\clpadt60 \clpadfr3\clpadr60 \cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \brdrb\brdrs \keepn\trhdr N=73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 52/53 (98.1%) \cell -\pard\intbl\qc\fs18 2.3007 (2.2724, 2.3290) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 68/72 (94.4%) \cell -\pard\intbl\qc\fs18 2.2968 (2.2691, 2.3246) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 29/53 (54.7%) \cell -\pard\intbl\qc\fs18 2.2876 (2.2419, 2.3334) \cell -\pard\intbl\qc\fs18 -0.0120 (-0.0500, 0.0259) \cell -\pard\intbl\qc\fs18 31/67 (46.3%) \cell -\pard\intbl\qc\fs18 2.2922 (2.2438, 2.3406) \cell -\pard\intbl\qc\fs18 -0.0217 (-0.0655, 0.0221) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 21/53 (39.6%) \cell -\pard\intbl\qc\fs18 2.2954 (2.2425, 2.3483) \cell -\pard\intbl\qc\fs18 -0.0095 (-0.0609, 0.0419) \cell -\pard\intbl\qc\fs18 21/52 (40.4%) \cell -\pard\intbl\qc\fs18 2.2811 (2.2404, 2.3219) \cell -\pard\intbl\qc\fs18 -0.0238 (-0.0574, 0.0098) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 24/50 (48.0%) \cell -\pard\intbl\qc\fs18 2.2652 (2.2315, 2.2990) \cell -\pard\intbl\qc\fs18 -0.0353 (-0.0800, 0.0093) \cell -\pard\intbl\qc\fs18 25/47 (53.2%) \cell -\pard\intbl\qc\fs18 2.2824 (2.2360, 2.3289) \cell -\pard\intbl\qc\fs18 0.0010 (-0.0341, 0.0361) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 50/53 (94.3%) \cell -\pard\intbl\qc\fs18 5.2945 (4.9610, 5.6281) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 70/72 (97.2%) \cell -\pard\intbl\qc\fs18 5.4106 (5.1498, 5.6715) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 27/53 (50.9%) \cell -\pard\intbl\qc\fs18 6.7290 (5.0413, 8.4168) \cell -\pard\intbl\qc\fs18 1.0650 (-0.0754, 2.2054) \cell -\pard\intbl\qc\fs18 30/67 (44.8%) \cell -\pard\intbl\qc\fs18 5.3937 (4.9428, 5.8446) \cell -\pard\intbl\qc\fs18 0.0703 (-0.4232, 0.5638) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 27/53 (50.9%) \cell -\pard\intbl\qc\fs18 6.2644 (5.3223, 7.2065) \cell -\pard\intbl\qc\fs18 0.8162 (0.2610, 1.3715) \cell -\pard\intbl\qc\fs18 30/52 (57.7%) \cell -\pard\intbl\qc\fs18 5.4030 (4.9699, 5.8360) \cell -\pard\intbl\qc\fs18 -0.0259 (-0.3714, 0.3196) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 23/50 (46.0%) \cell -\pard\intbl\qc\fs18 6.6081 (4.7846, 8.4317) \cell -\pard\intbl\qc\fs18 1.0137 (-0.4353, 2.4626) \cell -\pard\intbl\qc\fs18 21/47 (44.7%) \cell -\pard\intbl\qc\fs18 5.2972 (4.9553, 5.6392) \cell -\pard\intbl\qc\fs18 -0.2220 (-0.6998, 0.2557) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 51/53 (96.2%) \cell -\pard\intbl\qc\fs18 4.27 (4.17, 4.37) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 68/72 (94.4%) \cell -\pard\intbl\qc\fs18 4.32 (4.24, 4.41) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 29/53 (54.7%) \cell -\pard\intbl\qc\fs18 4.32 (4.17, 4.47) \cell -\pard\intbl\qc\fs18 0.14 (-0.00, 0.28) \cell -\pard\intbl\qc\fs18 31/67 (46.3%) \cell -\pard\intbl\qc\fs18 4.25 (4.09, 4.41) \cell -\pard\intbl\qc\fs18 -0.05 (-0.22, 0.13) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 25/53 (47.2%) \cell -\pard\intbl\qc\fs18 4.22 (4.07, 4.38) \cell -\pard\intbl\qc\fs18 -0.22 (-0.40, -0.05) \cell -\pard\intbl\qc\fs18 24/52 (46.2%) \cell -\pard\intbl\qc\fs18 4.35 (4.14, 4.56) \cell -\pard\intbl\qc\fs18 -0.01 (-0.15, 0.13) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 24/50 (48.0%) \cell -\pard\intbl\qc\fs18 4.12 (3.98, 4.25) \cell -\pard\intbl\qc\fs18 -0.20 (-0.36, -0.03) \cell -\pard\intbl\qc\fs18 24/47 (51.1%) \cell -\pard\intbl\qc\fs18 4.25 (4.06, 4.45) \cell -\pard\intbl\qc\fs18 -0.03 (-0.23, 0.18) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 52/53 (98.1%) \cell -\pard\intbl\qc\fs18 139.9 (139.2, 140.6) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 69/72 (95.8%) \cell -\pard\intbl\qc\fs18 139.8 (139.1, 140.4) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 22/53 (41.5%) \cell -\pard\intbl\qc\fs18 138.7 (137.5, 139.9) \cell -\pard\intbl\qc\fs18 -1.3 (-2.7, 0.2) \cell -\pard\intbl\qc\fs18 35/67 (52.2%) \cell -\pard\intbl\qc\fs18 139.6 (138.6, 140.6) \cell -\pard\intbl\qc\fs18 0.4 (-0.7, 1.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 26/53 (49.1%) \cell -\pard\intbl\qc\fs18 139.5 (138.5, 140.6) \cell -\pard\intbl\qc\fs18 -0.3 (-1.6, 0.9) \cell -\pard\intbl\qc\fs18 24/52 (46.2%) \cell -\pard\intbl\qc\fs18 140.7 (139.6, 141.7) \cell -\pard\intbl\qc\fs18 0.8 (-0.4, 1.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2846 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3993 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5777 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7774 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8921 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10705 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 26/50 (52.0%) \cell -\pard\intbl\qc\fs18 140.5 (139.3, 141.7) \cell -\pard\intbl\qc\fs18 0.8 (-0.4, 2.0) \cell -\pard\intbl\qc\fs18 20/47 (42.6%) \cell -\pard\intbl\qc\fs18 140.3 (139.4, 141.3) \cell -\pard\intbl\qc\fs18 0.8 (-0.2, 1.7) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2846 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3993 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5777 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7774 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8921 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10705 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2846 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3993 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5777 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7774 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8921 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10705 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab01part2/tsflab01part2of2.rtf b/tests/testthat/_snaps/tsflab01part2/tsflab01part2of2.rtf deleted file mode 100644 index 34244504..00000000 --- a/tests/testthat/_snaps/tsflab01part2/tsflab01part2of2.rtf +++ /dev/null @@ -1,484 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4095 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8328 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10515 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB01part2of2:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4095 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6048 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8328 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10515 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4095 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6048 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8328 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4095 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6048 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 55/59 (93.2%) \cell -\pard\intbl\qc\fs18 2.3090 (2.2863, 2.3317) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 33/58 (56.9%) \cell -\pard\intbl\qc\fs18 2.2674 (2.2342, 2.3006) \cell -\pard\intbl\qc\fs18 -0.0295 (-0.0634, 0.0045) \cell -\pard\intbl\qc\fs18 0.0174 (-0.0324, 0.0673) \cell -\pard\intbl\qc\fs18 0.0078 (-0.0466, 0.0621) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 24/56 (42.9%) \cell -\pard\intbl\qc\fs18 2.2621 (2.2299, 2.2944) \cell -\pard\intbl\qc\fs18 -0.0322 (-0.0626, -0.0019) \cell -\pard\intbl\qc\fs18 0.0227 (-0.0356, 0.0810) \cell -\pard\intbl\qc\fs18 0.0085 (-0.0355, 0.0524) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 24/51 (47.1%) \cell -\pard\intbl\qc\fs18 2.2819 (2.2374, 2.3263) \cell -\pard\intbl\qc\fs18 -0.0187 (-0.0681, 0.0306) \cell -\pard\intbl\qc\fs18 -0.0166 (-0.0814, 0.0482) \cell -\pard\intbl\qc\fs18 0.0197 (-0.0394, 0.0788) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 57/59 (96.6%) \cell -\pard\intbl\qc\fs18 5.3124 (5.0333, 5.5915) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 31/58 (53.4%) \cell -\pard\intbl\qc\fs18 5.4471 (4.9675, 5.9268) \cell -\pard\intbl\qc\fs18 0.0376 (-0.4162, 0.4914) \cell -\pard\intbl\qc\fs18 1.0274 (-0.1869, 2.2416) \cell -\pard\intbl\qc\fs18 0.0327 (-0.6238, 0.6892) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 22/56 (39.3%) \cell -\pard\intbl\qc\fs18 5.3365 (4.7634, 5.9096) \cell -\pard\intbl\qc\fs18 -0.0454 (-0.7575, 0.6667) \cell -\pard\intbl\qc\fs18 0.8616 (-0.0185, 1.7417) \cell -\pard\intbl\qc\fs18 0.0195 (-0.7591, 0.7981) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 21/51 (41.2%) \cell -\pard\intbl\qc\fs18 5.5378 (4.6876, 6.3880) \cell -\pard\intbl\qc\fs18 0.0529 (-0.5992, 0.7050) \cell -\pard\intbl\qc\fs18 0.9608 (-0.6016, 2.5232) \cell -\pard\intbl\qc\fs18 -0.2749 (-1.0604, 0.5106) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 57/59 (96.6%) \cell -\pard\intbl\qc\fs18 4.26 (4.14, 4.37) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 30/58 (51.7%) \cell -\pard\intbl\qc\fs18 4.28 (4.13, 4.43) \cell -\pard\intbl\qc\fs18 0.04 (-0.11, 0.20) \cell -\pard\intbl\qc\fs18 0.10 (-0.11, 0.31) \cell -\pard\intbl\qc\fs18 -0.09 (-0.32, 0.14) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 28/56 (50.0%) \cell -\pard\intbl\qc\fs18 4.14 (3.97, 4.31) \cell -\pard\intbl\qc\fs18 -0.10 (-0.27, 0.07) \cell -\pard\intbl\qc\fs18 -0.12 (-0.36, 0.12) \cell -\pard\intbl\qc\fs18 0.09 (-0.12, 0.31) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 28/51 (54.9%) \cell -\pard\intbl\qc\fs18 4.27 (4.13, 4.41) \cell -\pard\intbl\qc\fs18 0.01 (-0.15, 0.17) \cell -\pard\intbl\qc\fs18 -0.21 (-0.43, 0.02) \cell -\pard\intbl\qc\fs18 -0.04 (-0.29, 0.22) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 57/59 (96.6%) \cell -\pard\intbl\qc\fs18 140.7 (140.0, 141.4) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 31/58 (53.4%) \cell -\pard\intbl\qc\fs18 140.4 (139.2, 141.6) \cell -\pard\intbl\qc\fs18 0.5 (-0.8, 1.8) \cell -\pard\intbl\qc\fs18 -1.8 (-3.7, 0.2) \cell -\pard\intbl\qc\fs18 -0.1 (-1.7, 1.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 26/56 (46.4%) \cell -\pard\intbl\qc\fs18 139.7 (138.6, 140.7) \cell -\pard\intbl\qc\fs18 -1.0 (-2.3, 0.4) \cell -\pard\intbl\qc\fs18 0.6 (-1.2, 2.4) \cell -\pard\intbl\qc\fs18 1.7 (-0.0, 3.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4095 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6048 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8328 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10515 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 22/51 (43.1%) \cell -\pard\intbl\qc\fs18 140.3 (139.4, 141.2) \cell -\pard\intbl\qc\fs18 -0.8 (-2.2, 0.6) \cell -\pard\intbl\qc\fs18 1.6 (-0.2, 3.4) \cell -\pard\intbl\qc\fs18 1.5 (-0.1, 3.2) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4095 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6048 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8328 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10515 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4095 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6048 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8328 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10515 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab02/tsflab02.rtf b/tests/testthat/_snaps/tsflab02/tsflab02.rtf old mode 100755 new mode 100644 index e0185746..1ee1cc39 --- a/tests/testthat/_snaps/tsflab02/tsflab02.rtf +++ b/tests/testthat/_snaps/tsflab02/tsflab02.rtf @@ -3,30 +3,34 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4502 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6190 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7878 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10290 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4123 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5387 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6783 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8180 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10374 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB02:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2814 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4502 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6190 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7878 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10290 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2860 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4123 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5387 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6783 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8180 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10374 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell @@ -35,31 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4502 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7878 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10290 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10374 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Threshold Level, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -67,12 +75,14 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium, low \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, male \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -83,15 +93,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 50 \cell -\pard\intbl\qc\fs18 61 \cell -\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 16 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -99,76 +111,194 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<2.096 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (125-135 g/L) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 0.0 (-16.8, 16.8) \cell +\pard\intbl\qc\fs18 7.4 (-11.2, 26.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<125 g/L) \cell +\pard\intbl\qc\fs18 3 (18.8%) \cell +\pard\intbl\qc\fs18 4 (18.2%) \cell +\pard\intbl\qc\fs18 7 (18.4%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18.8 (-0.4, 37.9) \cell +\pard\intbl\qc\fs18 18.2 (2.1, 34.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 3 (<105 g/L) \cell +\pard\intbl\qc\fs18 2 (12.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 2 (12.5%) \cell +\pard\intbl\qc\fs18 0.0 (-22.9, 22.9) \cell +\pard\intbl\qc\fs18 -12.5 (-28.7, 3.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs18 17 (34.0%) \cell -\pard\intbl\qc\fs18 15 (24.6%) \cell -\pard\intbl\qc\fs18 13 (23.2%) \cell -\pard\intbl\qc\fs18 10.8 (-6.4, 28.0) \cell -\pard\intbl\qc\fs18 1.4 (-14.1, 16.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 3 (<1.871 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, female \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (110-120 g/L) \cell +\pard\intbl\qc\fs18 5 (20.0%) \cell +\pard\intbl\qc\fs18 1 (5.6%) \cell +\pard\intbl\qc\fs18 6 (14.0%) \cell +\pard\intbl\qc\fs18 2 (6.1%) \cell +\pard\intbl\qc\fs18 13.9 (-3.7, 31.6) \cell +\pard\intbl\qc\fs18 -0.5 (-13.9, 12.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<110 g/L) \cell +\pard\intbl\qc\fs18 5 (20.0%) \cell +\pard\intbl\qc\fs18 1 (5.6%) \cell +\pard\intbl\qc\fs18 6 (14.0%) \cell +\pard\intbl\qc\fs18 6 (18.2%) \cell +\pard\intbl\qc\fs18 1.8 (-18.7, 22.3) \cell +\pard\intbl\qc\fs18 -12.6 (-29.5, 4.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 3 (<95 g/L) \cell +\pard\intbl\qc\fs18 1 (4.0%) \cell +\pard\intbl\qc\fs18 2 (11.1%) \cell +\pard\intbl\qc\fs18 3 (7.0%) \cell +\pard\intbl\qc\fs18 6 (18.2%) \cell +\pard\intbl\qc\fs18 -14.2 (-29.4, 1.1) \cell +\pard\intbl\qc\fs18 -7.1 (-26.7, 12.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose, low \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, low \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -179,15 +309,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 47 \cell -\pard\intbl\qc\fs18 58 \cell -\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 83 \cell +\pard\intbl\qc\fs18 54 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -195,65 +327,415 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<3.89 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<3.5 10^9/L) \cell +\pard\intbl\qc\fs18 6 (15.0%) \cell +\pard\intbl\qc\fs18 3 (7.0%) \cell +\pard\intbl\qc\fs18 9 (10.8%) \cell +\pard\intbl\qc\fs18 9 (16.7%) \cell +\pard\intbl\qc\fs18 -1.7 (-16.5, 13.2) \cell +\pard\intbl\qc\fs18 -9.7 (-22.2, 2.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4502 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6190 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7878 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10290 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<3.00 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<3.0 10^9/L) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\pard\intbl\qc\fs18 7 (16.3%) \cell +\pard\intbl\qc\fs18 9 (10.8%) \cell +\pard\intbl\qc\fs18 7 (13.0%) \cell +\pard\intbl\qc\fs18 -8.0 (-19.2, 3.3) \cell +\pard\intbl\qc\fs18 3.3 (-10.9, 17.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 3 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 7 (17.5%) \cell +\pard\intbl\qc\fs18 8 (18.6%) \cell +\pard\intbl\qc\fs18 15 (18.1%) \cell +\pard\intbl\qc\fs18 8 (14.8%) \cell +\pard\intbl\qc\fs18 2.7 (-12.4, 17.8) \cell +\pard\intbl\qc\fs18 3.8 (-11.2, 18.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, high \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 83 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (>10.8 10^9/L) \cell +\pard\intbl\qc\fs18 5 (12.2%) \cell +\pard\intbl\qc\fs18 7 (16.7%) \cell +\pard\intbl\qc\fs18 12 (14.5%) \cell +\pard\intbl\qc\fs18 3 (6.0%) \cell +\pard\intbl\qc\fs18 6.2 (-5.8, 18.2) \cell +\pard\intbl\qc\fs18 10.7 (-2.4, 23.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (>13.0 10^9/L) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 3 (7.1%) \cell +\pard\intbl\qc\fs18 4 (4.8%) \cell +\pard\intbl\qc\fs18 6 (12.0%) \cell +\pard\intbl\qc\fs18 -9.6 (-19.7, 0.6) \cell +\pard\intbl\qc\fs18 -4.9 (-16.8, 7.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 3 (>15.0 10^9/L) \cell +\pard\intbl\qc\fs18 7 (17.1%) \cell +\pard\intbl\qc\fs18 2 (4.8%) \cell +\pard\intbl\qc\fs18 9 (10.8%) \cell +\pard\intbl\qc\fs18 9 (18.0%) \cell +\pard\intbl\qc\fs18 -0.9 (-16.6, 14.8) \cell +\pard\intbl\qc\fs18 -13.2 (-25.7, -0.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Platelets, low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 75 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<140 10^9/L) \cell +\pard\intbl\qc\fs18 7 (19.4%) \cell +\pard\intbl\qc\fs18 7 (17.9%) \cell +\pard\intbl\qc\fs18 14 (18.7%) \cell +\pard\intbl\qc\fs18 6 (13.3%) \cell +\pard\intbl\qc\fs18 6.1 (-10.2, 22.4) \cell +\pard\intbl\qc\fs18 4.6 (-11.0, 20.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<125 10^9/L) \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell +\pard\intbl\qc\fs18 4 (10.3%) \cell +\pard\intbl\qc\fs18 6 (8.0%) \cell +\pard\intbl\qc\fs18 8 (17.8%) \cell +\pard\intbl\qc\fs18 -12.2 (-25.7, 1.2) \cell +\pard\intbl\qc\fs18 -7.5 (-22.2, 7.2) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4502 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6190 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7878 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10290 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 3 (<100 10^9/L) \cell +\pard\intbl\qc\fs18 6 (16.7%) \cell +\pard\intbl\qc\fs18 5 (12.8%) \cell +\pard\intbl\qc\fs18 11 (14.7%) \cell +\pard\intbl\qc\fs18 5 (11.1%) \cell +\pard\intbl\qc\fs18 5.6 (-9.7, 20.8) \cell +\pard\intbl\qc\fs18 1.7 (-12.2, 15.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Neutrophils, low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 79 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<2.0 10^9/L) \cell +\pard\intbl\qc\fs18 6 (15.0%) \cell +\pard\intbl\qc\fs18 5 (12.8%) \cell +\pard\intbl\qc\fs18 11 (13.9%) \cell +\pard\intbl\qc\fs18 6 (13.0%) \cell +\pard\intbl\qc\fs18 2.0 (-12.8, 16.7) \cell +\pard\intbl\qc\fs18 -0.2 (-14.5, 14.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 8 (20.0%) \cell +\pard\intbl\qc\fs18 5 (12.8%) \cell +\pard\intbl\qc\fs18 13 (16.5%) \cell +\pard\intbl\qc\fs18 15 (32.6%) \cell +\pard\intbl\qc\fs18 -12.6 (-31.0, 5.8) \cell +\pard\intbl\qc\fs18 -19.8 (-36.9, -2.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4123 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5387 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6783 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8180 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10374 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 3 (<0.5 10^9/L) \cell +\pard\intbl\qc\fs18 5 (12.5%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 7 (8.9%) \cell +\pard\intbl\qc\fs18 5 (10.9%) \cell +\pard\intbl\qc\fs18 1.6 (-12.0, 15.3) \cell +\pard\intbl\qc\fs18 -5.7 (-17.1, 5.6) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4123 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5387 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6783 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8180 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10374 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4502 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6190 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7878 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10290 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4123 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5387 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6783 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8180 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10374 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsflab02a/tsflab02a.rtf b/tests/testthat/_snaps/tsflab02a/tsflab02a.rtf deleted file mode 100755 index b64231ce..00000000 --- a/tests/testthat/_snaps/tsflab02a/tsflab02a.rtf +++ /dev/null @@ -1,676 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2856 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4435 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6013 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7441 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10071 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB02a:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2856 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4435 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6013 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7441 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10071 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Threshold Level, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium, low \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 6 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<2.096 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 2 (33.3%) \cell -\pard\intbl\qc\fs18 -8.3 (-56.5, 39.9) \cell -\pard\intbl\qc\fs18 -13.3 (-64.8, 38.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 3 (<1.871 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose, low \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<3.89 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<3.00 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium, low \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 14 \cell -\pard\intbl\qc\fs18 12 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<2.096 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell -\pard\intbl\qc\fs18 3 (25.0%) \cell -\pard\intbl\qc\fs18 5 (26.3%) \cell -\pard\intbl\qc\fs18 -12.0 (-39.0, 15.0) \cell -\pard\intbl\qc\fs18 -1.3 (-32.8, 30.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 3 (<1.871 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose, low \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 13 \cell -\pard\intbl\qc\fs18 12 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<3.89 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<3.00 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium, low \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 28 \cell -\pard\intbl\qc\fs18 44 \cell -\pard\intbl\qc\fs18 31 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<2.096 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs18 13 (46.4%) \cell -\pard\intbl\qc\fs18 11 (25.0%) \cell -\pard\intbl\qc\fs18 6 (19.4%) \cell -\pard\intbl\qc\fs18 27.1 (4.0, 50.2) \cell -\pard\intbl\qc\fs18 5.6 (-13.3, 24.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 3 (<1.871 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose, low \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 26 \cell -\pard\intbl\qc\fs18 42 \cell -\pard\intbl\qc\fs18 30 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 1 (<3.89 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7441 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Level 2 (<3.00 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2856 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4435 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6013 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7441 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10071 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7441 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab02b/tsflab02b.rtf b/tests/testthat/_snaps/tsflab02b/tsflab02b.rtf old mode 100755 new mode 100644 index f701f264..bd5f2a08 --- a/tests/testthat/_snaps/tsflab02b/tsflab02b.rtf +++ b/tests/testthat/_snaps/tsflab02b/tsflab02b.rtf @@ -3,28 +3,32 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4341 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5869 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7396 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10049 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6864 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8211 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10456 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB02b:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2814 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4341 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5869 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7396 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10049 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6864 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8211 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10456 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell @@ -35,31 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Laboratory Test \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Threshold Level, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -67,15 +75,17 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 49 \cell -\pard\intbl\qc\fs18 63 \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, male \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 23 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -83,12 +93,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Calcium, low \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -99,15 +111,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 15 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 17 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -115,76 +129,86 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 1 (<2.096 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (125-135 g/L) \cell +\pard\intbl\qc\fs18 6 (28.6%) \cell +\pard\intbl\qc\fs18 4 (18.2%) \cell +\pard\intbl\qc\fs18 10 (23.3%) \cell +\pard\intbl\qc\fs18 3 (17.6%) \cell +\pard\intbl\qc\fs18 10.9 (-15.6, 37.4) \cell +\pard\intbl\qc\fs18 0.5 (-23.7, 24.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (18.8%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 -6.2 (-18.1, 5.6) \cell -\pard\intbl\qc\fs18 12.5 (-10.0, 35.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 g/L) \cell +\pard\intbl\qc\fs18 3 (14.3%) \cell +\pard\intbl\qc\fs18 6 (27.3%) \cell +\pard\intbl\qc\fs18 9 (20.9%) \cell +\pard\intbl\qc\fs18 4 (23.5%) \cell +\pard\intbl\qc\fs18 -9.2 (-34.4, 15.9) \cell +\pard\intbl\qc\fs18 3.7 (-23.7, 31.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 3 (<1.871 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<105 g/L) \cell +\pard\intbl\qc\fs18 7 (33.3%) \cell +\pard\intbl\qc\fs18 7 (31.8%) \cell +\pard\intbl\qc\fs18 14 (32.6%) \cell +\pard\intbl\qc\fs18 6 (35.3%) \cell +\pard\intbl\qc\fs18 -2.0 (-32.3, 28.4) \cell +\pard\intbl\qc\fs18 -3.5 (-33.4, 26.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Glucose, low \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -195,15 +219,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell \pard\intbl\qc\fs18 13 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 20 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -211,63 +237,305 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 1 (<3.89 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (125-135 g/L) \cell +\pard\intbl\qc\fs18 4 (30.8%) \cell +\pard\intbl\qc\fs18 4 (19.0%) \cell +\pard\intbl\qc\fs18 8 (23.5%) \cell +\pard\intbl\qc\fs18 4 (20.0%) \cell +\pard\intbl\qc\fs18 10.8 (-19.8, 41.4) \cell +\pard\intbl\qc\fs18 -1.0 (-25.2, 23.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 g/L) \cell +\pard\intbl\qc\fs18 3 (23.1%) \cell +\pard\intbl\qc\fs18 8 (38.1%) \cell +\pard\intbl\qc\fs18 11 (32.4%) \cell +\pard\intbl\qc\fs18 9 (45.0%) \cell +\pard\intbl\qc\fs18 -21.9 (-53.5, 9.7) \cell +\pard\intbl\qc\fs18 -6.9 (-37.0, 23.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 2 (<3.00 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<105 g/L) \cell +\pard\intbl\qc\fs18 4 (30.8%) \cell +\pard\intbl\qc\fs18 6 (28.6%) \cell +\pard\intbl\qc\fs18 10 (29.4%) \cell +\pard\intbl\qc\fs18 6 (30.0%) \cell +\pard\intbl\qc\fs18 0.8 (-31.4, 32.9) \cell +\pard\intbl\qc\fs18 -1.4 (-29.3, 26.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 52 \cell -\pard\intbl\qc\fs18 50 \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (125-135 g/L) \cell +\pard\intbl\qc\fs18 1 (9.1%) \cell +\pard\intbl\qc\fs18 4 (17.4%) \cell +\pard\intbl\qc\fs18 5 (14.7%) \cell +\pard\intbl\qc\fs18 3 (20.0%) \cell +\pard\intbl\qc\fs18 -10.9 (-37.3, 15.5) \cell +\pard\intbl\qc\fs18 -2.6 (-28.1, 22.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 g/L) \cell +\pard\intbl\qc\fs18 4 (36.4%) \cell +\pard\intbl\qc\fs18 6 (26.1%) \cell +\pard\intbl\qc\fs18 10 (29.4%) \cell +\pard\intbl\qc\fs18 6 (40.0%) \cell +\pard\intbl\qc\fs18 -3.6 (-41.4, 34.1) \cell +\pard\intbl\qc\fs18 -13.9 (-44.5, 16.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<105 g/L) \cell +\pard\intbl\qc\fs18 2 (18.2%) \cell +\pard\intbl\qc\fs18 7 (30.4%) \cell +\pard\intbl\qc\fs18 9 (26.5%) \cell +\pard\intbl\qc\fs18 3 (20.0%) \cell +\pard\intbl\qc\fs18 -1.8 (-32.3, 28.7) \cell +\pard\intbl\qc\fs18 10.4 (-17.2, 38.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, female \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (110-120 g/L) \cell +\pard\intbl\qc\fs18 7 (23.3%) \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 10 (20.4%) \cell +\pard\intbl\qc\fs18 12 (40.0%) \cell +\pard\intbl\qc\fs18 -16.7 (-39.8, 6.5) \cell +\pard\intbl\qc\fs18 -24.2 (-48.2, -0.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<110 g/L) \cell +\pard\intbl\qc\fs18 12 (40.0%) \cell +\pard\intbl\qc\fs18 8 (42.1%) \cell +\pard\intbl\qc\fs18 20 (40.8%) \cell +\pard\intbl\qc\fs18 6 (20.0%) \cell +\pard\intbl\qc\fs18 20.0 (-2.6, 42.6) \cell +\pard\intbl\qc\fs18 22.1 (-4.3, 48.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<95 g/L) \cell +\pard\intbl\qc\fs18 5 (16.7%) \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 8 (16.3%) \cell +\pard\intbl\qc\fs18 6 (20.0%) \cell +\pard\intbl\qc\fs18 -3.3 (-22.9, 16.2) \cell +\pard\intbl\qc\fs18 -4.2 (-26.0, 17.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -275,12 +543,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Calcium, low \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -291,15 +561,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 12 \cell -\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 23 \cell \pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 27 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -307,76 +579,86 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 1 (<2.096 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (110-120 g/L) \cell +\pard\intbl\qc\fs18 7 (30.4%) \cell +\pard\intbl\qc\fs18 4 (23.5%) \cell +\pard\intbl\qc\fs18 11 (27.5%) \cell +\pard\intbl\qc\fs18 5 (18.5%) \cell +\pard\intbl\qc\fs18 11.9 (-11.9, 35.8) \cell +\pard\intbl\qc\fs18 5.0 (-19.9, 29.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 -11.8 (-27.1, 3.6) \cell -\pard\intbl\qc\fs18 2.5 (-21.4, 26.4) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<110 g/L) \cell +\pard\intbl\qc\fs18 6 (26.1%) \cell +\pard\intbl\qc\fs18 5 (29.4%) \cell +\pard\intbl\qc\fs18 11 (27.5%) \cell +\pard\intbl\qc\fs18 6 (22.2%) \cell +\pard\intbl\qc\fs18 3.9 (-20.0, 27.7) \cell +\pard\intbl\qc\fs18 7.2 (-19.6, 33.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 3 (<1.871 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<95 g/L) \cell +\pard\intbl\qc\fs18 6 (26.1%) \cell +\pard\intbl\qc\fs18 5 (29.4%) \cell +\pard\intbl\qc\fs18 11 (27.5%) \cell +\pard\intbl\qc\fs18 8 (29.6%) \cell +\pard\intbl\qc\fs18 -3.5 (-28.4, 21.3) \cell +\pard\intbl\qc\fs18 -0.2 (-27.9, 27.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Glucose, low \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -387,15 +669,107 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 9 \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (110-120 g/L) \cell +\pard\intbl\qc\fs18 2 (9.5%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 3 (8.1%) \cell +\pard\intbl\qc\fs18 6 (25.0%) \cell +\pard\intbl\qc\fs18 -15.5 (-36.9, 5.9) \cell +\pard\intbl\qc\fs18 -18.8 (-39.7, 2.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<110 g/L) \cell +\pard\intbl\qc\fs18 10 (47.6%) \cell +\pard\intbl\qc\fs18 7 (43.8%) \cell +\pard\intbl\qc\fs18 17 (45.9%) \cell +\pard\intbl\qc\fs18 6 (25.0%) \cell +\pard\intbl\qc\fs18 22.6 (-4.9, 50.1) \cell +\pard\intbl\qc\fs18 18.8 (-11.1, 48.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<95 g/L) \cell +\pard\intbl\qc\fs18 2 (9.5%) \cell +\pard\intbl\qc\fs18 4 (25.0%) \cell +\pard\intbl\qc\fs18 6 (16.2%) \cell +\pard\intbl\qc\fs18 4 (16.7%) \cell +\pard\intbl\qc\fs18 -7.1 (-26.6, 12.3) \cell +\pard\intbl\qc\fs18 8.3 (-17.6, 34.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, low \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 108 \cell +\pard\intbl\qc\fs18 62 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -403,63 +777,125 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 1 (<3.89 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 90 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<3.5 10^9/L) \cell +\pard\intbl\qc\fs18 10 (20.8%) \cell +\pard\intbl\qc\fs18 9 (21.4%) \cell +\pard\intbl\qc\fs18 19 (21.1%) \cell +\pard\intbl\qc\fs18 14 (27.5%) \cell +\pard\intbl\qc\fs18 -6.6 (-23.4, 10.2) \cell +\pard\intbl\qc\fs18 -6.0 (-23.5, 11.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<3.0 10^9/L) \cell +\pard\intbl\qc\fs18 10 (20.8%) \cell +\pard\intbl\qc\fs18 7 (16.7%) \cell +\pard\intbl\qc\fs18 17 (18.9%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 1.2 (-14.6, 17.1) \cell +\pard\intbl\qc\fs18 -2.9 (-18.6, 12.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 2 (<3.00 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 15 (31.3%) \cell +\pard\intbl\qc\fs18 15 (35.7%) \cell +\pard\intbl\qc\fs18 30 (33.3%) \cell +\pard\intbl\qc\fs18 14 (27.5%) \cell +\pard\intbl\qc\fs18 3.8 (-14.1, 21.7) \cell +\pard\intbl\qc\fs18 8.3 (-10.7, 27.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 45 \cell -\pard\intbl\qc\fs18 45 \cell -\pard\intbl\qc\fs18 47 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -467,12 +903,104 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Calcium, low \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 77 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<3.5 10^9/L) \cell +\pard\intbl\qc\fs18 14 (38.9%) \cell +\pard\intbl\qc\fs18 10 (24.4%) \cell +\pard\intbl\qc\fs18 24 (31.2%) \cell +\pard\intbl\qc\fs18 13 (26.5%) \cell +\pard\intbl\qc\fs18 12.4 (-7.8, 32.5) \cell +\pard\intbl\qc\fs18 -2.1 (-20.2, 15.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<3.0 10^9/L) \cell +\pard\intbl\qc\fs18 8 (22.2%) \cell +\pard\intbl\qc\fs18 16 (39.0%) \cell +\pard\intbl\qc\fs18 24 (31.2%) \cell +\pard\intbl\qc\fs18 10 (20.4%) \cell +\pard\intbl\qc\fs18 1.8 (-15.8, 19.5) \cell +\pard\intbl\qc\fs18 18.6 (-0.1, 37.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 7 (19.4%) \cell +\pard\intbl\qc\fs18 9 (22.0%) \cell +\pard\intbl\qc\fs18 16 (20.8%) \cell +\pard\intbl\qc\fs18 14 (28.6%) \cell +\pard\intbl\qc\fs18 -9.1 (-27.2, 9.0) \cell +\pard\intbl\qc\fs18 -6.6 (-24.5, 11.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -483,15 +1011,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 71 \cell +\pard\intbl\qc\fs18 43 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -499,76 +1029,104 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 1 (<2.096 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<3.5 10^9/L) \cell +\pard\intbl\qc\fs18 8 (25.8%) \cell +\pard\intbl\qc\fs18 10 (25.0%) \cell +\pard\intbl\qc\fs18 18 (25.4%) \cell +\pard\intbl\qc\fs18 16 (37.2%) \cell +\pard\intbl\qc\fs18 -11.4 (-32.5, 9.7) \cell +\pard\intbl\qc\fs18 -12.2 (-31.9, 7.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 2 (<1.996 mmol/L) \cell -\pard\intbl\qc\fs18 3 (27.3%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 2 (14.3%) \cell -\pard\intbl\qc\fs18 13.0 (-19.1, 45.1) \cell -\pard\intbl\qc\fs18 -8.0 (-29.9, 13.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<3.0 10^9/L) \cell +\pard\intbl\qc\fs18 4 (12.9%) \cell +\pard\intbl\qc\fs18 12 (30.0%) \cell +\pard\intbl\qc\fs18 16 (22.5%) \cell +\pard\intbl\qc\fs18 8 (18.6%) \cell +\pard\intbl\qc\fs18 -5.7 (-22.3, 10.9) \cell +\pard\intbl\qc\fs18 11.4 (-7.0, 29.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 3 (<1.871 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 11 (35.5%) \cell +\pard\intbl\qc\fs18 10 (25.0%) \cell +\pard\intbl\qc\fs18 21 (29.6%) \cell +\pard\intbl\qc\fs18 12 (27.9%) \cell +\pard\intbl\qc\fs18 7.6 (-14.0, 29.1) \cell +\pard\intbl\qc\fs18 -2.9 (-21.9, 16.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Glucose, low \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, high \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 109 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -579,15 +1137,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 9 \cell -\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 90 \cell +\pard\intbl\qc\fs18 49 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -595,60 +1155,986 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 1 (<3.89 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (>10.8 10^9/L) \cell +\pard\intbl\qc\fs18 9 (18.8%) \cell +\pard\intbl\qc\fs18 10 (23.8%) \cell +\pard\intbl\qc\fs18 19 (21.1%) \cell +\pard\intbl\qc\fs18 8 (16.3%) \cell +\pard\intbl\qc\fs18 2.4 (-12.7, 17.6) \cell +\pard\intbl\qc\fs18 7.5 (-9.0, 24.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Level 2 (<3.00 mmol/L) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (>13.0 10^9/L) \cell +\pard\intbl\qc\fs18 11 (22.9%) \cell +\pard\intbl\qc\fs18 6 (14.3%) \cell +\pard\intbl\qc\fs18 17 (18.9%) \cell +\pard\intbl\qc\fs18 17 (34.7%) \cell +\pard\intbl\qc\fs18 -11.8 (-29.6, 6.1) \cell +\pard\intbl\qc\fs18 -20.4 (-37.4, -3.4) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4341 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5869 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7396 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10049 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (>15.0 10^9/L) \cell +\pard\intbl\qc\fs18 13 (27.1%) \cell +\pard\intbl\qc\fs18 14 (33.3%) \cell +\pard\intbl\qc\fs18 27 (30.0%) \cell +\pard\intbl\qc\fs18 8 (16.3%) \cell +\pard\intbl\qc\fs18 10.8 (-5.5, 27.0) \cell +\pard\intbl\qc\fs18 17.0 (-0.6, 34.6) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (>10.8 10^9/L) \cell +\pard\intbl\qc\fs18 10 (28.6%) \cell +\pard\intbl\qc\fs18 9 (20.9%) \cell +\pard\intbl\qc\fs18 19 (24.4%) \cell +\pard\intbl\qc\fs18 11 (25.0%) \cell +\pard\intbl\qc\fs18 3.6 (-16.1, 23.3) \cell +\pard\intbl\qc\fs18 -4.1 (-21.7, 13.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (>13.0 10^9/L) \cell +\pard\intbl\qc\fs18 10 (28.6%) \cell +\pard\intbl\qc\fs18 11 (25.6%) \cell +\pard\intbl\qc\fs18 21 (26.9%) \cell +\pard\intbl\qc\fs18 11 (25.0%) \cell +\pard\intbl\qc\fs18 3.6 (-16.1, 23.3) \cell +\pard\intbl\qc\fs18 0.6 (-17.7, 18.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (>15.0 10^9/L) \cell +\pard\intbl\qc\fs18 9 (25.7%) \cell +\pard\intbl\qc\fs18 7 (16.3%) \cell +\pard\intbl\qc\fs18 16 (20.5%) \cell +\pard\intbl\qc\fs18 15 (34.1%) \cell +\pard\intbl\qc\fs18 -8.4 (-28.5, 11.8) \cell +\pard\intbl\qc\fs18 -17.8 (-35.6, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (>10.8 10^9/L) \cell +\pard\intbl\qc\fs18 6 (18.2%) \cell +\pard\intbl\qc\fs18 9 (27.3%) \cell +\pard\intbl\qc\fs18 15 (22.7%) \cell +\pard\intbl\qc\fs18 5 (11.4%) \cell +\pard\intbl\qc\fs18 6.8 (-9.3, 23.0) \cell +\pard\intbl\qc\fs18 15.9 (-1.9, 33.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (>13.0 10^9/L) \cell +\pard\intbl\qc\fs18 11 (33.3%) \cell +\pard\intbl\qc\fs18 9 (27.3%) \cell +\pard\intbl\qc\fs18 20 (30.3%) \cell +\pard\intbl\qc\fs18 18 (40.9%) \cell +\pard\intbl\qc\fs18 -7.6 (-29.2, 14.1) \cell +\pard\intbl\qc\fs18 -13.6 (-34.7, 7.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (>15.0 10^9/L) \cell +\pard\intbl\qc\fs18 6 (18.2%) \cell +\pard\intbl\qc\fs18 8 (24.2%) \cell +\pard\intbl\qc\fs18 14 (21.2%) \cell +\pard\intbl\qc\fs18 12 (27.3%) \cell +\pard\intbl\qc\fs18 -9.1 (-27.7, 9.5) \cell +\pard\intbl\qc\fs18 -3.0 (-22.7, 16.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Platelets, low \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 85 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<140 10^9/L) \cell +\pard\intbl\qc\fs18 13 (28.9%) \cell +\pard\intbl\qc\fs18 8 (20.0%) \cell +\pard\intbl\qc\fs18 21 (24.7%) \cell +\pard\intbl\qc\fs18 5 (11.6%) \cell +\pard\intbl\qc\fs18 17.3 (0.9, 33.6) \cell +\pard\intbl\qc\fs18 8.4 (-7.3, 24.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 10^9/L) \cell +\pard\intbl\qc\fs18 7 (15.6%) \cell +\pard\intbl\qc\fs18 10 (25.0%) \cell +\pard\intbl\qc\fs18 17 (20.0%) \cell +\pard\intbl\qc\fs18 7 (16.3%) \cell +\pard\intbl\qc\fs18 -0.7 (-16.0, 14.6) \cell +\pard\intbl\qc\fs18 8.7 (-8.7, 26.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<100 10^9/L) \cell +\pard\intbl\qc\fs18 8 (17.8%) \cell +\pard\intbl\qc\fs18 11 (27.5%) \cell +\pard\intbl\qc\fs18 19 (22.4%) \cell +\pard\intbl\qc\fs18 16 (37.2%) \cell +\pard\intbl\qc\fs18 -19.4 (-37.7, -1.2) \cell +\pard\intbl\qc\fs18 -9.7 (-29.7, 10.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<140 10^9/L) \cell +\pard\intbl\qc\fs18 11 (28.2%) \cell +\pard\intbl\qc\fs18 7 (18.9%) \cell +\pard\intbl\qc\fs18 18 (23.7%) \cell +\pard\intbl\qc\fs18 15 (30.6%) \cell +\pard\intbl\qc\fs18 -2.4 (-21.5, 16.7) \cell +\pard\intbl\qc\fs18 -11.7 (-29.7, 6.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 10^9/L) \cell +\pard\intbl\qc\fs18 12 (30.8%) \cell +\pard\intbl\qc\fs18 9 (24.3%) \cell +\pard\intbl\qc\fs18 21 (27.6%) \cell +\pard\intbl\qc\fs18 11 (22.4%) \cell +\pard\intbl\qc\fs18 8.3 (-10.3, 26.9) \cell +\pard\intbl\qc\fs18 1.9 (-16.2, 20.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<100 10^9/L) \cell +\pard\intbl\qc\fs18 9 (23.1%) \cell +\pard\intbl\qc\fs18 8 (21.6%) \cell +\pard\intbl\qc\fs18 17 (22.4%) \cell +\pard\intbl\qc\fs18 12 (24.5%) \cell +\pard\intbl\qc\fs18 -1.4 (-19.3, 16.5) \cell +\pard\intbl\qc\fs18 -2.9 (-20.8, 15.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<140 10^9/L) \cell +\pard\intbl\qc\fs18 6 (19.4%) \cell +\pard\intbl\qc\fs18 9 (25.7%) \cell +\pard\intbl\qc\fs18 15 (22.7%) \cell +\pard\intbl\qc\fs18 6 (15.8%) \cell +\pard\intbl\qc\fs18 3.6 (-14.5, 21.7) \cell +\pard\intbl\qc\fs18 9.9 (-8.6, 28.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 10^9/L) \cell +\pard\intbl\qc\fs18 11 (35.5%) \cell +\pard\intbl\qc\fs18 12 (34.3%) \cell +\pard\intbl\qc\fs18 23 (34.8%) \cell +\pard\intbl\qc\fs18 14 (36.8%) \cell +\pard\intbl\qc\fs18 -1.4 (-24.1, 21.4) \cell +\pard\intbl\qc\fs18 -2.6 (-24.5, 19.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<100 10^9/L) \cell +\pard\intbl\qc\fs18 7 (22.6%) \cell +\pard\intbl\qc\fs18 10 (28.6%) \cell +\pard\intbl\qc\fs18 17 (25.8%) \cell +\pard\intbl\qc\fs18 10 (26.3%) \cell +\pard\intbl\qc\fs18 -3.7 (-24.0, 16.6) \cell +\pard\intbl\qc\fs18 2.3 (-18.2, 22.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Neutrophils, low \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 106 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 85 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<2.0 10^9/L) \cell +\pard\intbl\qc\fs18 12 (25.5%) \cell +\pard\intbl\qc\fs18 9 (23.7%) \cell +\pard\intbl\qc\fs18 21 (24.7%) \cell +\pard\intbl\qc\fs18 8 (18.2%) \cell +\pard\intbl\qc\fs18 7.4 (-9.5, 24.2) \cell +\pard\intbl\qc\fs18 5.5 (-12.2, 23.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 15 (31.9%) \cell +\pard\intbl\qc\fs18 11 (28.9%) \cell +\pard\intbl\qc\fs18 26 (30.6%) \cell +\pard\intbl\qc\fs18 23 (52.3%) \cell +\pard\intbl\qc\fs18 -20.4 (-40.2, -0.5) \cell +\pard\intbl\qc\fs18 -23.3 (-44.0, -2.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<0.5 10^9/L) \cell +\pard\intbl\qc\fs18 9 (19.1%) \cell +\pard\intbl\qc\fs18 10 (26.3%) \cell +\pard\intbl\qc\fs18 19 (22.4%) \cell +\pard\intbl\qc\fs18 7 (15.9%) \cell +\pard\intbl\qc\fs18 3.2 (-12.4, 18.8) \cell +\pard\intbl\qc\fs18 10.4 (-7.3, 28.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 74 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<2.0 10^9/L) \cell +\pard\intbl\qc\fs18 15 (40.5%) \cell +\pard\intbl\qc\fs18 11 (29.7%) \cell +\pard\intbl\qc\fs18 26 (35.1%) \cell +\pard\intbl\qc\fs18 14 (26.4%) \cell +\pard\intbl\qc\fs18 14.1 (-5.7, 33.9) \cell +\pard\intbl\qc\fs18 3.3 (-15.6, 22.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 8 (21.6%) \cell +\pard\intbl\qc\fs18 9 (24.3%) \cell +\pard\intbl\qc\fs18 17 (23.0%) \cell +\pard\intbl\qc\fs18 14 (26.4%) \cell +\pard\intbl\qc\fs18 -4.8 (-22.6, 13.0) \cell +\pard\intbl\qc\fs18 -2.1 (-20.3, 16.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<0.5 10^9/L) \cell +\pard\intbl\qc\fs18 7 (18.9%) \cell +\pard\intbl\qc\fs18 9 (24.3%) \cell +\pard\intbl\qc\fs18 16 (21.6%) \cell +\pard\intbl\qc\fs18 16 (30.2%) \cell +\pard\intbl\qc\fs18 -11.3 (-28.9, 6.4) \cell +\pard\intbl\qc\fs18 -5.9 (-24.4, 12.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<2.0 10^9/L) \cell +\pard\intbl\qc\fs18 4 (13.8%) \cell +\pard\intbl\qc\fs18 12 (35.3%) \cell +\pard\intbl\qc\fs18 16 (25.4%) \cell +\pard\intbl\qc\fs18 14 (31.8%) \cell +\pard\intbl\qc\fs18 -18.0 (-36.7, 0.6) \cell +\pard\intbl\qc\fs18 3.5 (-17.7, 24.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 10 (34.5%) \cell +\pard\intbl\qc\fs18 8 (23.5%) \cell +\pard\intbl\qc\fs18 18 (28.6%) \cell +\pard\intbl\qc\fs18 8 (18.2%) \cell +\pard\intbl\qc\fs18 16.3 (-4.4, 37.0) \cell +\pard\intbl\qc\fs18 5.3 (-12.9, 23.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<0.5 10^9/L) \cell +\pard\intbl\qc\fs18 6 (20.7%) \cell +\pard\intbl\qc\fs18 6 (17.6%) \cell +\pard\intbl\qc\fs18 12 (19.0%) \cell +\pard\intbl\qc\fs18 11 (25.0%) \cell +\pard\intbl\qc\fs18 -4.3 (-23.8, 15.2) \cell +\pard\intbl\qc\fs18 -7.4 (-25.5, 10.8) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6864 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8211 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10456 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsflab02c/tsflab02c.rtf b/tests/testthat/_snaps/tsflab02c/tsflab02c.rtf new file mode 100644 index 00000000..dff403e2 --- /dev/null +++ b/tests/testthat/_snaps/tsflab02c/tsflab02c.rtf @@ -0,0 +1,274 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4319 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5779 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7240 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8701 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10606 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB02c:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2858 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4319 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5779 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7240 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8701 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10606 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4319 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5779 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7240 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8701 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10606 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4319 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5779 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7240 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8701 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10606 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Criteria \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4319 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5779 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7240 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8701 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10606 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin (g/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4319 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7240 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8701 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10606 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4319 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7240 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8701 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10606 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 >2xULN \cell +\pard\intbl\qc\fs18 28 (68.3%) \cell +\pard\intbl\qc\fs18 21 (46.7%) \cell +\pard\intbl\qc\fs18 49 (57.0%) \cell +\pard\intbl\qc\fs18 35 (60.3%) \cell +\pard\intbl\qc\fs18 7.9 (-11.1, 27.0) \cell +\pard\intbl\qc\fs18 -13.7 (-32.9, 5.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4319 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7240 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8701 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10606 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 >3xULN \cell +\pard\intbl\qc\fs18 35 (85.4%) \cell +\pard\intbl\qc\fs18 42 (93.3%) \cell +\pard\intbl\qc\fs18 77 (89.5%) \cell +\pard\intbl\qc\fs18 44 (75.9%) \cell +\pard\intbl\qc\fs18 9.5 (-5.9, 24.9) \cell +\pard\intbl\qc\fs18 17.5 (4.3, 30.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4319 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7240 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8701 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10606 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4319 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7240 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8701 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10606 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes (10^9/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4319 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7240 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8701 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10606 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4319 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5779 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7240 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8701 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10606 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 >2xULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4319 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5779 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7240 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8701 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10606 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 >3xULN \cell +\pard\intbl\qc\fs18 37 (100.0%) \cell +\pard\intbl\qc\fs18 32 (100.0%) \cell +\pard\intbl\qc\fs18 69 (100.0%) \cell +\pard\intbl\qc\fs18 46 (100.0%) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4319 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5779 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7240 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8701 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10606 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4319 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5779 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7240 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8701 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10606 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab03/tsflab03.rtf b/tests/testthat/_snaps/tsflab03/tsflab03.rtf old mode 100755 new mode 100644 index 6f689124..4ab74d39 --- a/tests/testthat/_snaps/tsflab03/tsflab03.rtf +++ b/tests/testthat/_snaps/tsflab03/tsflab03.rtf @@ -3,28 +3,32 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2856 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4435 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6013 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7591 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10071 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2830 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4081 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5463 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6844 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8226 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10530 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB03:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2856 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4435 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6013 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7591 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10071 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr NCI-CTCAE Category \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2830 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4081 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5463 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6844 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8226 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10530 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell @@ -35,31 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Laboratory Test \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10071 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10530 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Grade, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -67,28 +75,122 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blood and lymphatic system disorders \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alanine Aminotransferase, high \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 100 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 9 (9.0%) \cell +\pard\intbl\qc\fs18 7 (11.7%) \cell +\pard\intbl\qc\fs18 -9.6 (-18.7, -0.6) \cell +\pard\intbl\qc\fs18 4.0 (-8.8, 16.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 6 (12.2%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (12.0%) \cell +\pard\intbl\qc\fs18 6 (10.0%) \cell +\pard\intbl\qc\fs18 2.2 (-9.7, 14.2) \cell +\pard\intbl\qc\fs18 1.8 (-9.9, 13.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.0%) \cell +\pard\intbl\qc\fs18 4 (6.7%) \cell +\pard\intbl\qc\fs18 -4.6 (-12.1, 2.8) \cell +\pard\intbl\qc\fs18 -2.7 (-11.0, 5.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anemia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -99,15 +201,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Aspartate Aminotransferase, high \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 97 \cell +\pard\intbl\qc\fs18 60 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -115,76 +237,104 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 29 (54.7%) \cell -\pard\intbl\qc\fs18 42 (57.5%) \cell -\pard\intbl\qc\fs18 35 (59.3%) \cell -\pard\intbl\qc\fs18 -4.6 (-23.0, 13.7) \cell -\pard\intbl\qc\fs18 -1.8 (-18.7, 15.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 9 (18.0%) \cell +\pard\intbl\qc\fs18 14 (14.4%) \cell +\pard\intbl\qc\fs18 12 (20.0%) \cell +\pard\intbl\qc\fs18 -9.4 (-22.8, 4.1) \cell +\pard\intbl\qc\fs18 -2.0 (-16.7, 12.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 16 (30.2%) \cell -\pard\intbl\qc\fs18 24 (32.9%) \cell -\pard\intbl\qc\fs18 23 (39.0%) \cell -\pard\intbl\qc\fs18 -8.8 (-26.3, 8.7) \cell -\pard\intbl\qc\fs18 -6.1 (-22.6, 10.4) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\pard\intbl\qc\fs18 6 (12.0%) \cell +\pard\intbl\qc\fs18 10 (10.3%) \cell +\pard\intbl\qc\fs18 4 (6.7%) \cell +\pard\intbl\qc\fs18 1.8 (-8.3, 12.0) \cell +\pard\intbl\qc\fs18 5.3 (-5.7, 16.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell -\pard\intbl\qc\fs18 0.6 (-14.8, 16.1) \cell -\pard\intbl\qc\fs18 2.6 (-11.9, 17.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4.3 (-1.5, 10.0) \cell +\pard\intbl\qc\fs18 2.0 (-1.9, 5.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Leukocytosis \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Bilirubin, high \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -195,15 +345,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -211,12 +363,68 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 6 (12.2%) \cell +\pard\intbl\qc\fs18 6 (12.2%) \cell +\pard\intbl\qc\fs18 12 (12.2%) \cell +\pard\intbl\qc\fs18 8 (13.1%) \cell +\pard\intbl\qc\fs18 -0.9 (-13.4, 11.6) \cell +\pard\intbl\qc\fs18 -0.9 (-13.4, 11.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (4.1%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell +\pard\intbl\qc\fs18 -2.9 (-9.6, 3.8) \cell +\pard\intbl\qc\fs18 -0.8 (-8.6, 6.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 3 (6.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell +\pard\intbl\qc\fs18 1.2 (-7.4, 9.8) \cell +\pard\intbl\qc\fs18 -2.9 (-9.6, 3.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -227,28 +435,140 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Creatinine, high \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 100 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 6 (12.2%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 14 (14.0%) \cell +\pard\intbl\qc\fs18 10 (16.9%) \cell +\pard\intbl\qc\fs18 -4.7 (-18.0, 8.6) \cell +\pard\intbl\qc\fs18 -1.3 (-15.1, 12.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 2 (4.1%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 9 (9.0%) \cell +\pard\intbl\qc\fs18 6 (10.2%) \cell +\pard\intbl\qc\fs18 -6.1 (-15.6, 3.4) \cell +\pard\intbl\qc\fs18 3.6 (-8.6, 15.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 2 (4.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (4.0%) \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 0.7 (-6.5, 7.9) \cell +\pard\intbl\qc\fs18 0.5 (-6.5, 7.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutritional disorders \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -259,12 +579,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperkalemia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose, low \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -275,15 +597,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 100 \cell +\pard\intbl\qc\fs18 62 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -291,44 +615,50 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -339,12 +669,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -355,28 +687,32 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypernatremia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, low \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -387,15 +723,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 100 \cell +\pard\intbl\qc\fs18 62 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -403,44 +741,50 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 9 (15.3%) \cell -\pard\intbl\qc\fs18 -3.9 (-16.5, 8.6) \cell -\pard\intbl\qc\fs18 -8.4 (-19.3, 2.4) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.7, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.7, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -451,44 +795,140 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, high \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 80 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 3 (8.1%) \cell +\pard\intbl\qc\fs18 2 (4.7%) \cell +\pard\intbl\qc\fs18 5 (6.3%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 -1.6 (-14.3, 11.0) \cell +\pard\intbl\qc\fs18 -5.1 (-16.2, 5.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 7 (18.9%) \cell +\pard\intbl\qc\fs18 11 (25.6%) \cell +\pard\intbl\qc\fs18 18 (22.5%) \cell +\pard\intbl\qc\fs18 5 (12.2%) \cell +\pard\intbl\qc\fs18 6.7 (-9.4, 22.8) \cell +\pard\intbl\qc\fs18 13.4 (-3.1, 29.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 6 (16.2%) \cell +\pard\intbl\qc\fs18 14 (32.6%) \cell +\pard\intbl\qc\fs18 20 (25.0%) \cell +\pard\intbl\qc\fs18 13 (31.7%) \cell +\pard\intbl\qc\fs18 -15.5 (-34.0, 3.1) \cell +\pard\intbl\qc\fs18 0.9 (-19.1, 20.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoalbuminemia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, low \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -499,15 +939,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 100 \cell +\pard\intbl\qc\fs18 62 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -515,76 +957,104 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 37 (69.8%) \cell -\pard\intbl\qc\fs18 32 (43.8%) \cell -\pard\intbl\qc\fs18 40 (67.8%) \cell -\pard\intbl\qc\fs18 2.0 (-15.2, 19.2) \cell -\pard\intbl\qc\fs18 -24.0 (-40.4, -7.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.7, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.7, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 23 (43.4%) \cell -\pard\intbl\qc\fs18 21 (28.8%) \cell -\pard\intbl\qc\fs18 25 (42.4%) \cell -\pard\intbl\qc\fs18 1.0 (-17.3, 19.4) \cell -\pard\intbl\qc\fs18 -13.6 (-29.9, 2.7) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 10 (13.7%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 -4.7 (-20.2, 10.9) \cell -\pard\intbl\qc\fs18 -11.7 (-25.4, 1.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoglycemia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, high \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -595,15 +1065,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 72 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 31 \cell \pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 39 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -611,92 +1083,176 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 33 (45.8%) \cell -\pard\intbl\qc\fs18 37 (62.7%) \cell -\pard\intbl\qc\fs18 -6.1 (-24.3, 12.1) \cell -\pard\intbl\qc\fs18 -16.9 (-33.8, -0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 7 (25.0%) \cell +\pard\intbl\qc\fs18 15 (48.4%) \cell +\pard\intbl\qc\fs18 22 (37.3%) \cell +\pard\intbl\qc\fs18 14 (35.9%) \cell +\pard\intbl\qc\fs18 -10.9 (-32.9, 11.1) \cell +\pard\intbl\qc\fs18 12.5 (-10.7, 35.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 25 (47.2%) \cell -\pard\intbl\qc\fs18 23 (31.9%) \cell -\pard\intbl\qc\fs18 23 (39.0%) \cell -\pard\intbl\qc\fs18 8.2 (-10.1, 26.5) \cell -\pard\intbl\qc\fs18 -7.0 (-23.5, 9.4) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 17 (23.6%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 -2.8 (-18.6, 13.0) \cell -\pard\intbl\qc\fs18 -1.8 (-16.6, 13.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Platelets, low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 99 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 4.0) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2.1 (-2.0, 6.1) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypokalemia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium, low \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -707,15 +1263,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 58 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 100 \cell +\pard\intbl\qc\fs18 62 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -723,76 +1281,86 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 23 (31.5%) \cell -\pard\intbl\qc\fs18 20 (34.5%) \cell -\pard\intbl\qc\fs18 3.3 (-14.6, 21.1) \cell -\pard\intbl\qc\fs18 -3.0 (-19.2, 13.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 -1.6 (-4.7, 1.5) \cell +\pard\intbl\qc\fs18 -1.6 (-4.7, 1.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 15 (25.9%) \cell -\pard\intbl\qc\fs18 -5.1 (-20.8, 10.6) \cell -\pard\intbl\qc\fs18 -10.8 (-24.7, 3.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 0.3 (-6.6, 7.3) \cell -\pard\intbl\qc\fs18 2.0 (-5.0, 9.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyponatremia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium, high \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -803,15 +1371,17 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 80 \cell +\pard\intbl\qc\fs18 39 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -819,81 +1389,217 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 36 (67.9%) \cell -\pard\intbl\qc\fs18 40 (56.3%) \cell -\pard\intbl\qc\fs18 40 (67.8%) \cell -\pard\intbl\qc\fs18 0.1 (-17.2, 17.5) \cell -\pard\intbl\qc\fs18 -11.5 (-28.0, 5.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 4 (10.3%) \cell +\pard\intbl\qc\fs18 8 (10.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 7.2 (-3.2, 17.5) \cell +\pard\intbl\qc\fs18 7.7 (-3.0, 18.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 16 (30.2%) \cell -\pard\intbl\qc\fs18 14 (19.7%) \cell -\pard\intbl\qc\fs18 12 (20.3%) \cell -\pard\intbl\qc\fs18 9.8 (-6.2, 25.9) \cell -\pard\intbl\qc\fs18 -0.6 (-14.4, 13.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 8 (19.5%) \cell +\pard\intbl\qc\fs18 12 (30.8%) \cell +\pard\intbl\qc\fs18 20 (25.0%) \cell +\pard\intbl\qc\fs18 7 (17.9%) \cell +\pard\intbl\qc\fs18 1.6 (-15.5, 18.7) \cell +\pard\intbl\qc\fs18 12.8 (-6.0, 31.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2856 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4435 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6013 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7591 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10071 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 7 (17.1%) \cell +\pard\intbl\qc\fs18 9 (23.1%) \cell +\pard\intbl\qc\fs18 16 (20.0%) \cell +\pard\intbl\qc\fs18 12 (30.8%) \cell +\pard\intbl\qc\fs18 -13.7 (-32.2, 4.8) \cell +\pard\intbl\qc\fs18 -7.7 (-27.3, 11.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 4 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5.7 (-0.6, 11.9) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2856 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4435 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6013 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7591 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10071 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Urinary Protein, high \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 99 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 1 \cell +\pard\intbl\qc\fs18 6 (12.2%) \cell +\pard\intbl\qc\fs18 3 (6.0%) \cell +\pard\intbl\qc\fs18 9 (9.1%) \cell +\pard\intbl\qc\fs18 7 (11.7%) \cell +\pard\intbl\qc\fs18 0.6 (-11.7, 12.8) \cell +\pard\intbl\qc\fs18 -5.7 (-16.1, 4.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 2 \cell +\pard\intbl\qc\fs18 6 (12.2%) \cell +\pard\intbl\qc\fs18 6 (12.0%) \cell +\pard\intbl\qc\fs18 12 (12.1%) \cell +\pard\intbl\qc\fs18 5 (8.3%) \cell +\pard\intbl\qc\fs18 3.9 (-7.6, 15.5) \cell +\pard\intbl\qc\fs18 3.7 (-7.7, 15.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4081 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5463 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6844 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8226 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10530 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Grade 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\pard\intbl\qc\fs18 -3.3 (-7.9, 1.2) \cell +\pard\intbl\qc\fs18 -1.3 (-7.3, 4.6) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2830 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4081 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5463 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6844 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8226 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10530 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2856 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4435 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6013 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7591 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10071 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2830 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4081 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5463 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6844 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8226 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10530 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsflab03a/tsflab03a.rtf b/tests/testthat/_snaps/tsflab03a/tsflab03a.rtf deleted file mode 100755 index 6c23d745..00000000 --- a/tests/testthat/_snaps/tsflab03a/tsflab03a.rtf +++ /dev/null @@ -1,2596 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2815 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4330 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5846 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7361 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10031 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB03a:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2815 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4330 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5846 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7361 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10031 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr NCI-CTCAE Category \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Laboratory Test \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Grade, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blood and lymphatic system disorders \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 7 (87.5%) \cell -\pard\intbl\qc\fs18 5 (100.0%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 16.1 (-24.5, 56.6) \cell -\pard\intbl\qc\fs18 28.6 (-4.9, 62.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 5 (100.0%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 33.9 (-13.5, 81.3) \cell -\pard\intbl\qc\fs18 71.4 (38.0, 100.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25.0 (-5.0, 55.0) \cell -\pard\intbl\qc\fs18 40.0 (-2.9, 82.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Leukocytosis \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutritional disorders \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperkalemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypernatremia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 -14.3 (-40.2, 11.6) \cell -\pard\intbl\qc\fs18 -14.3 (-40.2, 11.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoalbuminemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 8 (100.0%) \cell -\pard\intbl\qc\fs18 4 (80.0%) \cell -\pard\intbl\qc\fs18 6 (85.7%) \cell -\pard\intbl\qc\fs18 14.3 (-11.6, 40.2) \cell -\pard\intbl\qc\fs18 -5.7 (-49.3, 37.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 7 (87.5%) \cell -\pard\intbl\qc\fs18 4 (80.0%) \cell -\pard\intbl\qc\fs18 6 (85.7%) \cell -\pard\intbl\qc\fs18 1.8 (-32.8, 36.4) \cell -\pard\intbl\qc\fs18 -5.7 (-49.3, 37.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 -17.9 (-65.2, 29.5) \cell -\pard\intbl\qc\fs18 -42.9 (-79.5, -6.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoglycemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 3 (60.0%) \cell -\pard\intbl\qc\fs18 7 (100.0%) \cell -\pard\intbl\qc\fs18 -50.0 (-84.6, -15.4) \cell -\pard\intbl\qc\fs18 -40.0 (-82.9, 2.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 6 (75.0%) \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 6 (85.7%) \cell -\pard\intbl\qc\fs18 -10.7 (-50.4, 28.9) \cell -\pard\intbl\qc\fs18 -45.7 (-95.9, 4.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 3 (60.0%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 19.6 (-30.0, 69.3) \cell -\pard\intbl\qc\fs18 17.1 (-39.3, 73.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 10.7 (-28.9, 50.4) \cell -\pard\intbl\qc\fs18 -14.3 (-40.2, 11.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypokalemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 5 (100.0%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 -21.4 (-69.6, 26.7) \cell -\pard\intbl\qc\fs18 28.6 (-4.9, 62.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 -17.9 (-65.2, 29.5) \cell -\pard\intbl\qc\fs18 -2.9 (-59.3, 53.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-10.4, 35.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyponatremia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 7 (87.5%) \cell -\pard\intbl\qc\fs18 4 (80.0%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 16.1 (-24.5, 56.6) \cell -\pard\intbl\qc\fs18 8.6 (-39.9, 57.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 -5.4 (-55.0, 44.3) \cell -\pard\intbl\qc\fs18 -22.9 (-73.6, 27.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blood and lymphatic system disorders \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 11 (68.8%) \cell -\pard\intbl\qc\fs18 10 (58.8%) \cell -\pard\intbl\qc\fs18 17 (89.5%) \cell -\pard\intbl\qc\fs18 -20.7 (-47.3, 5.9) \cell -\pard\intbl\qc\fs18 -30.7 (-57.8, -3.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 11 (68.8%) \cell -\pard\intbl\qc\fs18 8 (47.1%) \cell -\pard\intbl\qc\fs18 13 (68.4%) \cell -\pard\intbl\qc\fs18 0.3 (-30.5, 31.2) \cell -\pard\intbl\qc\fs18 -21.4 (-53.0, 10.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 9 (56.2%) \cell -\pard\intbl\qc\fs18 5 (29.4%) \cell -\pard\intbl\qc\fs18 9 (47.4%) \cell -\pard\intbl\qc\fs18 8.9 (-24.2, 42.0) \cell -\pard\intbl\qc\fs18 -18.0 (-49.2, 13.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Leukocytosis \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutritional disorders \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperkalemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypernatremia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 5 (26.3%) \cell -\pard\intbl\qc\fs18 -13.8 (-39.4, 11.8) \cell -\pard\intbl\qc\fs18 -14.6 (-39.6, 10.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoalbuminemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 15 (93.8%) \cell -\pard\intbl\qc\fs18 10 (58.8%) \cell -\pard\intbl\qc\fs18 18 (94.7%) \cell -\pard\intbl\qc\fs18 -1.0 (-16.5, 14.6) \cell -\pard\intbl\qc\fs18 -35.9 (-61.4, -10.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 10 (62.5%) \cell -\pard\intbl\qc\fs18 6 (35.3%) \cell -\pard\intbl\qc\fs18 14 (73.7%) \cell -\pard\intbl\qc\fs18 -11.2 (-42.1, 19.7) \cell -\pard\intbl\qc\fs18 -38.4 (-68.5, -8.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 7 (43.8%) \cell -\pard\intbl\qc\fs18 4 (23.5%) \cell -\pard\intbl\qc\fs18 6 (31.6%) \cell -\pard\intbl\qc\fs18 12.2 (-19.9, 44.2) \cell -\pard\intbl\qc\fs18 -8.0 (-37.1, 21.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoglycemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 13 (81.2%) \cell -\pard\intbl\qc\fs18 11 (64.7%) \cell -\pard\intbl\qc\fs18 18 (94.7%) \cell -\pard\intbl\qc\fs18 -13.5 (-35.1, 8.1) \cell -\pard\intbl\qc\fs18 -30.0 (-54.9, -5.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 11 (68.8%) \cell -\pard\intbl\qc\fs18 8 (47.1%) \cell -\pard\intbl\qc\fs18 10 (52.6%) \cell -\pard\intbl\qc\fs18 16.1 (-15.8, 48.1) \cell -\pard\intbl\qc\fs18 -5.6 (-38.2, 27.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 7 (43.8%) \cell -\pard\intbl\qc\fs18 5 (29.4%) \cell -\pard\intbl\qc\fs18 6 (31.6%) \cell -\pard\intbl\qc\fs18 12.2 (-19.9, 44.2) \cell -\pard\intbl\qc\fs18 -2.2 (-32.3, 27.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 2 (11.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6.2 (-5.6, 18.1) \cell -\pard\intbl\qc\fs18 11.8 (-3.6, 27.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypokalemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 12 (75.0%) \cell -\pard\intbl\qc\fs18 5 (31.2%) \cell -\pard\intbl\qc\fs18 11 (57.9%) \cell -\pard\intbl\qc\fs18 17.1 (-13.6, 47.8) \cell -\pard\intbl\qc\fs18 -26.6 (-58.4, 5.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 6 (37.5%) \cell -\pard\intbl\qc\fs18 4 (25.0%) \cell -\pard\intbl\qc\fs18 10 (52.6%) \cell -\pard\intbl\qc\fs18 -15.1 (-47.8, 17.5) \cell -\pard\intbl\qc\fs18 -27.6 (-58.5, 3.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 2 (10.5%) \cell -\pard\intbl\qc\fs18 -4.3 (-22.5, 13.9) \cell -\pard\intbl\qc\fs18 -4.3 (-22.5, 13.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyponatremia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 15 \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 14 (87.5%) \cell -\pard\intbl\qc\fs18 11 (73.3%) \cell -\pard\intbl\qc\fs18 17 (89.5%) \cell -\pard\intbl\qc\fs18 -2.0 (-23.3, 19.3) \cell -\pard\intbl\qc\fs18 -16.1 (-42.4, 10.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 5 (31.2%) \cell -\pard\intbl\qc\fs18 8 (53.3%) \cell -\pard\intbl\qc\fs18 7 (36.8%) \cell -\pard\intbl\qc\fs18 -5.6 (-37.0, 25.8) \cell -\pard\intbl\qc\fs18 16.5 (-16.8, 49.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 2 (12.5%) \cell -\pard\intbl\qc\fs18 1 (6.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 12.5 (-3.7, 28.7) \cell -\pard\intbl\qc\fs18 6.7 (-6.0, 19.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \pagebb Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blood and lymphatic system disorders \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 24 (82.8%) \cell -\pard\intbl\qc\fs18 41 (80.4%) \cell -\pard\intbl\qc\fs18 29 (87.9%) \cell -\pard\intbl\qc\fs18 -5.1 (-22.8, 12.6) \cell -\pard\intbl\qc\fs18 -7.5 (-23.1, 8.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 19 (65.5%) \cell -\pard\intbl\qc\fs18 25 (49.0%) \cell -\pard\intbl\qc\fs18 21 (63.6%) \cell -\pard\intbl\qc\fs18 1.9 (-22.0, 25.7) \cell -\pard\intbl\qc\fs18 -14.6 (-36.0, 6.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 10 (34.5%) \cell -\pard\intbl\qc\fs18 23 (45.1%) \cell -\pard\intbl\qc\fs18 12 (36.4%) \cell -\pard\intbl\qc\fs18 -1.9 (-25.7, 22.0) \cell -\pard\intbl\qc\fs18 8.7 (-12.6, 30.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Leukocytosis \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutritional disorders \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperkalemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 0.4 (-8.4, 9.3) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (3.0%) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\pard\intbl\qc\fs18 -3.0 (-8.9, 2.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypernatremia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\pard\intbl\qc\fs18 4 (7.8%) \cell -\pard\intbl\qc\fs18 4 (12.1%) \cell -\pard\intbl\qc\fs18 5.1 (-12.6, 22.8) \cell -\pard\intbl\qc\fs18 -4.3 (-17.6, 9.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 1 (3.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3.4 (-3.2, 10.1) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoalbuminemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 25 (86.2%) \cell -\pard\intbl\qc\fs18 38 (74.5%) \cell -\pard\intbl\qc\fs18 25 (75.8%) \cell -\pard\intbl\qc\fs18 10.4 (-8.8, 29.7) \cell -\pard\intbl\qc\fs18 -1.2 (-20.1, 17.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 17 (58.6%) \cell -\pard\intbl\qc\fs18 31 (60.8%) \cell -\pard\intbl\qc\fs18 20 (60.6%) \cell -\pard\intbl\qc\fs18 -2.0 (-26.5, 22.5) \cell -\pard\intbl\qc\fs18 0.2 (-21.2, 21.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 14 (48.3%) \cell -\pard\intbl\qc\fs18 15 (29.4%) \cell -\pard\intbl\qc\fs18 12 (36.4%) \cell -\pard\intbl\qc\fs18 11.9 (-12.6, 36.4) \cell -\pard\intbl\qc\fs18 -7.0 (-27.6, 13.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoglycemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 50 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 24 (82.8%) \cell -\pard\intbl\qc\fs18 36 (72.0%) \cell -\pard\intbl\qc\fs18 30 (90.9%) \cell -\pard\intbl\qc\fs18 -8.2 (-25.0, 8.7) \cell -\pard\intbl\qc\fs18 -18.9 (-34.8, -3.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 21 (72.4%) \cell -\pard\intbl\qc\fs18 25 (50.0%) \cell -\pard\intbl\qc\fs18 21 (63.6%) \cell -\pard\intbl\qc\fs18 8.8 (-14.3, 31.9) \cell -\pard\intbl\qc\fs18 -13.6 (-35.1, 7.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 9 (31.0%) \cell -\pard\intbl\qc\fs18 17 (34.0%) \cell -\pard\intbl\qc\fs18 14 (42.4%) \cell -\pard\intbl\qc\fs18 -11.4 (-35.2, 12.4) \cell -\pard\intbl\qc\fs18 -8.4 (-29.8, 12.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 2 (6.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (6.1%) \cell -\pard\intbl\qc\fs18 0.8 (-11.5, 13.1) \cell -\pard\intbl\qc\fs18 -6.1 (-14.2, 2.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypokalemia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 31 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 22 (75.9%) \cell -\pard\intbl\qc\fs18 28 (54.9%) \cell -\pard\intbl\qc\fs18 22 (71.0%) \cell -\pard\intbl\qc\fs18 4.9 (-17.4, 27.2) \cell -\pard\intbl\qc\fs18 -16.1 (-37.1, 5.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 17 (58.6%) \cell -\pard\intbl\qc\fs18 17 (33.3%) \cell -\pard\intbl\qc\fs18 15 (48.4%) \cell -\pard\intbl\qc\fs18 10.2 (-14.9, 35.3) \cell -\pard\intbl\qc\fs18 -15.1 (-36.9, 6.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 5 (9.8%) \cell -\pard\intbl\qc\fs18 2 (6.5%) \cell -\pard\intbl\qc\fs18 3.9 (-10.2, 18.0) \cell -\pard\intbl\qc\fs18 3.4 (-8.5, 15.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyponatremia \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 26 (89.7%) \cell -\pard\intbl\qc\fs18 38 (74.5%) \cell -\pard\intbl\qc\fs18 29 (87.9%) \cell -\pard\intbl\qc\fs18 1.8 (-13.9, 17.5) \cell -\pard\intbl\qc\fs18 -13.4 (-29.7, 3.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 13 (44.8%) \cell -\pard\intbl\qc\fs18 19 (37.3%) \cell -\pard\intbl\qc\fs18 15 (45.5%) \cell -\pard\intbl\qc\fs18 -0.6 (-25.5, 24.2) \cell -\pard\intbl\qc\fs18 -8.2 (-29.8, 13.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2815 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4330 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5846 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7361 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10031 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 3 (10.3%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10.3 (-0.7, 21.4) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2815 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4330 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5846 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7361 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10031 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2815 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4330 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5846 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7361 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10031 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab04a/tsflab04a.rtf b/tests/testthat/_snaps/tsflab04a/tsflab04a.rtf old mode 100755 new mode 100644 index dd8e4d6f..02c06424 --- a/tests/testthat/_snaps/tsflab04a/tsflab04a.rtf +++ b/tests/testthat/_snaps/tsflab04a/tsflab04a.rtf @@ -3,30 +3,34 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2837 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4578 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6319 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8059 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10316 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2835 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4366 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5897 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7428 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8959 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10830 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB04a:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2837 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4578 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6319 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8059 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10316 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2835 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4366 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5897 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7428 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8959 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10830 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell @@ -35,31 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Category \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Laboratory Test \u8805? Level 2, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \u8805? Level 2, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -67,289 +75,361 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General chemistry \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Albumin, low (<25.0 g/L) \cell +\pard\intbl\qc\fs18 20/47 (42.6%) \cell +\pard\intbl\qc\fs18 21/48 (43.8%) \cell +\pard\intbl\qc\fs18 41/95 (43.2%) \cell +\pard\intbl\qc\fs18 23/61 (37.7%) \cell +\pard\intbl\qc\fs18 4.8 (-13.8, 23.5) \cell +\pard\intbl\qc\fs18 6.0 (-12.5, 24.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Calcium, low (<1.996 mmol/L) \cell -\pard\intbl\qc\fs18 46/53 (86.8%) \cell -\pard\intbl\qc\fs18 53/68 (77.9%) \cell -\pard\intbl\qc\fs18 55/58 (94.8%) \cell -\pard\intbl\qc\fs18 -8.0 (-18.8, 2.7) \cell -\pard\intbl\qc\fs18 -16.9 (-28.3, -5.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium, high (>2.745 mmol/L) \cell +\pard\intbl\qc\fs18 15/47 (31.9%) \cell +\pard\intbl\qc\fs18 15/49 (30.6%) \cell +\pard\intbl\qc\fs18 30/96 (31.3%) \cell +\pard\intbl\qc\fs18 16/61 (26.2%) \cell +\pard\intbl\qc\fs18 5.7 (-11.6, 23.0) \cell +\pard\intbl\qc\fs18 4.4 (-12.6, 21.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Glucose, low (<3.00 mmol/L) \cell -\pard\intbl\qc\fs18 44/53 (83.0%) \cell -\pard\intbl\qc\fs18 51/70 (72.9%) \cell -\pard\intbl\qc\fs18 56/59 (94.9%) \cell -\pard\intbl\qc\fs18 -11.9 (-23.5, -0.3) \cell -\pard\intbl\qc\fs18 -22.1 (-33.9, -10.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Creatine Kinase, high (>5x ULN Enzyme U/L) \cell +\pard\intbl\qc\fs18 16/49 (32.7%) \cell +\pard\intbl\qc\fs18 17/48 (35.4%) \cell +\pard\intbl\qc\fs18 33/97 (34.0%) \cell +\pard\intbl\qc\fs18 19/62 (30.6%) \cell +\pard\intbl\qc\fs18 2.0 (-15.4, 19.4) \cell +\pard\intbl\qc\fs18 4.8 (-13.0, 22.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Glucose, high (fasting \u8805?6.99 mmol/L or random \u8805?11.10 mmol/L) \cell -\pard\intbl\qc\fs18 47/53 (88.7%) \cell -\pard\intbl\qc\fs18 55/69 (79.7%) \cell -\pard\intbl\qc\fs18 48/58 (82.8%) \cell -\pard\intbl\qc\fs18 5.9 (-7.0, 18.9) \cell -\pard\intbl\qc\fs18 -3.0 (-16.6, 10.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose, low (<3.00 mmol/L) \cell +\pard\intbl\qc\fs18 11/48 (22.9%) \cell +\pard\intbl\qc\fs18 10/47 (21.3%) \cell +\pard\intbl\qc\fs18 21/95 (22.1%) \cell +\pard\intbl\qc\fs18 10/62 (16.1%) \cell +\pard\intbl\qc\fs18 6.8 (-8.2, 21.8) \cell +\pard\intbl\qc\fs18 5.1 (-9.7, 20.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Potassium, high (>6.0 mmol/L) \cell -\pard\intbl\qc\fs18 49/53 (92.5%) \cell -\pard\intbl\qc\fs18 48/69 (69.6%) \cell -\pard\intbl\qc\fs18 54/58 (93.1%) \cell -\pard\intbl\qc\fs18 -0.7 (-10.3, 9.0) \cell -\pard\intbl\qc\fs18 -23.5 (-36.2, -10.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose, high (fasting \u8805?6.99 mmol/L or random \u8805?11.10 mmol/L) \cell +\pard\intbl\qc\fs18 13/45 (28.9%) \cell +\pard\intbl\qc\fs18 13/49 (26.5%) \cell +\pard\intbl\qc\fs18 26/94 (27.7%) \cell +\pard\intbl\qc\fs18 14/59 (23.7%) \cell +\pard\intbl\qc\fs18 5.2 (-12.0, 22.3) \cell +\pard\intbl\qc\fs18 2.8 (-13.6, 19.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sodium, high (>155 mmol/L) \cell -\pard\intbl\qc\fs18 45/53 (84.9%) \cell -\pard\intbl\qc\fs18 56/66 (84.8%) \cell -\pard\intbl\qc\fs18 50/58 (86.2%) \cell -\pard\intbl\qc\fs18 -1.3 (-14.4, 11.8) \cell -\pard\intbl\qc\fs18 -1.4 (-13.8, 11.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Phosphate, low (<0.646 mmol/L) \cell +\pard\intbl\qc\fs18 21/48 (43.8%) \cell +\pard\intbl\qc\fs18 12/48 (25.0%) \cell +\pard\intbl\qc\fs18 33/96 (34.4%) \cell +\pard\intbl\qc\fs18 21/62 (33.9%) \cell +\pard\intbl\qc\fs18 9.9 (-8.4, 28.2) \cell +\pard\intbl\qc\fs18 -8.9 (-25.9, 8.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium, low (<3.4 mmol/L) \cell +\pard\intbl\qc\fs18 21/49 (42.9%) \cell +\pard\intbl\qc\fs18 22/49 (44.9%) \cell +\pard\intbl\qc\fs18 43/98 (43.9%) \cell +\pard\intbl\qc\fs18 19/60 (31.7%) \cell +\pard\intbl\qc\fs18 11.2 (-7.0, 29.4) \cell +\pard\intbl\qc\fs18 13.2 (-5.0, 31.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Lipids \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium, high (>6.0 mmol/L) \cell +\pard\intbl\qc\fs18 17/48 (35.4%) \cell +\pard\intbl\qc\fs18 25/51 (49.0%) \cell +\pard\intbl\qc\fs18 42/99 (42.4%) \cell +\pard\intbl\qc\fs18 20/61 (32.8%) \cell +\pard\intbl\qc\fs18 2.6 (-15.3, 20.6) \cell +\pard\intbl\qc\fs18 16.2 (-1.9, 34.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HDL Cholesterol, males, low (<0.776 mmol/L) \cell -\pard\intbl\qc\fs18 44/53 (83.0%) \cell -\pard\intbl\qc\fs18 54/71 (76.1%) \cell -\pard\intbl\qc\fs18 51/59 (86.4%) \cell -\pard\intbl\qc\fs18 -3.4 (-16.8, 9.9) \cell -\pard\intbl\qc\fs18 -10.4 (-23.6, 2.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium, low (<130 mmol/L) \cell +\pard\intbl\qc\fs18 20/44 (45.5%) \cell +\pard\intbl\qc\fs18 24/51 (47.1%) \cell +\pard\intbl\qc\fs18 44/95 (46.3%) \cell +\pard\intbl\qc\fs18 18/59 (30.5%) \cell +\pard\intbl\qc\fs18 14.9 (-3.9, 33.8) \cell +\pard\intbl\qc\fs18 16.6 (-1.5, 34.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Triglycerides, high (>3.387 mmol/L) \cell -\pard\intbl\qc\fs18 45/53 (84.9%) \cell -\pard\intbl\qc\fs18 52/73 (71.2%) \cell -\pard\intbl\qc\fs18 54/59 (91.5%) \cell -\pard\intbl\qc\fs18 -6.6 (-18.6, 5.4) \cell -\pard\intbl\qc\fs18 -20.3 (-32.9, -7.7) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium, high (>155 mmol/L) \cell +\pard\intbl\qc\fs18 13/47 (27.7%) \cell +\pard\intbl\qc\fs18 18/50 (36.0%) \cell +\pard\intbl\qc\fs18 31/97 (32.0%) \cell +\pard\intbl\qc\fs18 20/61 (32.8%) \cell +\pard\intbl\qc\fs18 -5.1 (-22.5, 12.3) \cell +\pard\intbl\qc\fs18 3.2 (-14.6, 21.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Liver biochemistry \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cholesterol, high (>6.206 mmol/L) \cell +\pard\intbl\qc\fs18 22/48 (45.8%) \cell +\pard\intbl\qc\fs18 23/49 (46.9%) \cell +\pard\intbl\qc\fs18 45/97 (46.4%) \cell +\pard\intbl\qc\fs18 27/57 (47.4%) \cell +\pard\intbl\qc\fs18 -1.5 (-20.7, 17.6) \cell +\pard\intbl\qc\fs18 -0.4 (-19.5, 18.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alanine Aminotransferase, high (>5x ULN Enzyme U/L) \cell -\pard\intbl\qc\fs18 51/53 (96.2%) \cell -\pard\intbl\qc\fs18 51/70 (72.9%) \cell -\pard\intbl\qc\fs18 47/58 (81.0%) \cell -\pard\intbl\qc\fs18 15.2 (3.9, 26.5) \cell -\pard\intbl\qc\fs18 -8.2 (-22.7, 6.3) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 LDL Cholesterol, high (>4.138 mmol/L) \cell +\pard\intbl\qc\fs18 21/48 (43.8%) \cell +\pard\intbl\qc\fs18 19/48 (39.6%) \cell +\pard\intbl\qc\fs18 40/96 (41.7%) \cell +\pard\intbl\qc\fs18 25/59 (42.4%) \cell +\pard\intbl\qc\fs18 1.4 (-17.5, 20.2) \cell +\pard\intbl\qc\fs18 -2.8 (-21.5, 15.9) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Albumin, low (<25.0 g/L) \cell -\pard\intbl\qc\fs18 44/53 (83.0%) \cell -\pard\intbl\qc\fs18 52/67 (77.6%) \cell -\pard\intbl\qc\fs18 50/59 (84.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-15.4, 11.9) \cell -\pard\intbl\qc\fs18 -7.1 (-20.7, 6.4) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Triglycerides, high (>3.387 mmol/L) \cell +\pard\intbl\qc\fs18 14/48 (29.2%) \cell +\pard\intbl\qc\fs18 17/50 (34.0%) \cell +\pard\intbl\qc\fs18 31/98 (31.6%) \cell +\pard\intbl\qc\fs18 19/59 (32.2%) \cell +\pard\intbl\qc\fs18 -3.0 (-20.6, 14.5) \cell +\pard\intbl\qc\fs18 1.8 (-15.9, 19.5) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alkaline Phosphatase, high (>2x ULN Enzyme U/L) \cell -\pard\intbl\qc\fs18 47/52 (90.4%) \cell -\pard\intbl\qc\fs18 53/69 (76.8%) \cell -\pard\intbl\qc\fs18 49/58 (84.5%) \cell -\pard\intbl\qc\fs18 5.9 (-6.4, 18.2) \cell -\pard\intbl\qc\fs18 -7.7 (-21.3, 6.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2837 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4578 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6319 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8059 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10316 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Aspartate Aminotransferase, high (>5x ULN Enzyme U/L) \cell -\pard\intbl\qc\fs18 49/53 (92.5%) \cell -\pard\intbl\qc\fs18 54/71 (76.1%) \cell -\pard\intbl\qc\fs18 55/58 (94.8%) \cell -\pard\intbl\qc\fs18 -2.4 (-11.5, 6.7) \cell -\pard\intbl\qc\fs18 -18.8 (-30.2, -7.3) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alanine Aminotransferase, high (>5x ULN Enzyme U/L) \cell +\pard\intbl\qc\fs18 12/46 (26.1%) \cell +\pard\intbl\qc\fs18 14/51 (27.5%) \cell +\pard\intbl\qc\fs18 26/97 (26.8%) \cell +\pard\intbl\qc\fs18 20/58 (34.5%) \cell +\pard\intbl\qc\fs18 -8.4 (-26.0, 9.2) \cell +\pard\intbl\qc\fs18 -7.0 (-24.3, 10.3) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2837 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4578 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6319 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8059 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10316 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alkaline Phosphatase, high (>2x ULN Enzyme U/L) \cell +\pard\intbl\qc\fs18 15/46 (32.6%) \cell +\pard\intbl\qc\fs18 22/50 (44.0%) \cell +\pard\intbl\qc\fs18 37/96 (38.5%) \cell +\pard\intbl\qc\fs18 23/59 (39.0%) \cell +\pard\intbl\qc\fs18 -6.4 (-24.8, 12.0) \cell +\pard\intbl\qc\fs18 5.0 (-13.5, 23.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Bilirubin, high (>2x ULN umol/L) \cell +\pard\intbl\qc\fs18 15/48 (31.3%) \cell +\pard\intbl\qc\fs18 18/47 (38.3%) \cell +\pard\intbl\qc\fs18 33/95 (34.7%) \cell +\pard\intbl\qc\fs18 24/60 (40.0%) \cell +\pard\intbl\qc\fs18 -8.8 (-26.8, 9.3) \cell +\pard\intbl\qc\fs18 -1.7 (-20.3, 16.9) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2835 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4366 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5897 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7428 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8959 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10830 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2837 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4578 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6319 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8059 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10316 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsflab04b/tsflab04b.rtf b/tests/testthat/_snaps/tsflab04b/tsflab04b.rtf old mode 100755 new mode 100644 index 9e261fad..61a831b6 --- a/tests/testthat/_snaps/tsflab04b/tsflab04b.rtf +++ b/tests/testthat/_snaps/tsflab04b/tsflab04b.rtf @@ -3,30 +3,34 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2845 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4631 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6417 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8203 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10386 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2835 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4366 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5897 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7428 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8959 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10830 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB04b:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2845 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4631 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6417 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8203 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10386 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2835 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4366 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5897 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7428 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8959 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10830 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell @@ -35,31 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Category \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Laboratory Test \u8805? Level 2, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \u8805? Level 2, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -67,12 +75,68 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Complete blood count \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, female (<110 g/L) \cell +\pard\intbl\qc\fs18 13/31 (41.9%) \cell +\pard\intbl\qc\fs18 8/22 (36.4%) \cell +\pard\intbl\qc\fs18 21/53 (39.6%) \cell +\pard\intbl\qc\fs18 15/37 (40.5%) \cell +\pard\intbl\qc\fs18 1.4 (-22.1, 24.9) \cell +\pard\intbl\qc\fs18 -4.2 (-29.8, 21.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, low (<3.0 10^9/L) \cell +\pard\intbl\qc\fs18 18/46 (39.1%) \cell +\pard\intbl\qc\fs18 17/49 (34.7%) \cell +\pard\intbl\qc\fs18 35/95 (36.8%) \cell +\pard\intbl\qc\fs18 21/59 (35.6%) \cell +\pard\intbl\qc\fs18 3.5 (-15.1, 22.2) \cell +\pard\intbl\qc\fs18 -0.9 (-19.0, 17.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Platelets, low (<125 10^9/L) \cell +\pard\intbl\qc\fs18 19/46 (41.3%) \cell +\pard\intbl\qc\fs18 16/48 (33.3%) \cell +\pard\intbl\qc\fs18 35/94 (37.2%) \cell +\pard\intbl\qc\fs18 23/59 (39.0%) \cell +\pard\intbl\qc\fs18 2.3 (-16.6, 21.2) \cell +\pard\intbl\qc\fs18 -5.6 (-23.9, 12.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -83,49 +147,73 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hemoglobin, male (<125 g/L) \cell -\pard\intbl\qc\fs18 47/53 (88.7%) \cell -\pard\intbl\qc\fs18 54/71 (76.1%) \cell -\pard\intbl\qc\fs18 53/59 (89.8%) \cell -\pard\intbl\qc\fs18 -1.2 (-12.7, 10.3) \cell -\pard\intbl\qc\fs18 -13.8 (-26.3, -1.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Eosinophils, high (>1.5 10^9/L) \cell +\pard\intbl\qc\fs18 15/47 (31.9%) \cell +\pard\intbl\qc\fs18 25/50 (50.0%) \cell +\pard\intbl\qc\fs18 40/97 (41.2%) \cell +\pard\intbl\qc\fs18 22/57 (38.6%) \cell +\pard\intbl\qc\fs18 -6.7 (-25.0, 11.7) \cell +\pard\intbl\qc\fs18 11.4 (-7.4, 30.2) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2845 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4631 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6417 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8203 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10386 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2835 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4366 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5897 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7428 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8959 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10830 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Neutrophils, low (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 21/48 (43.8%) \cell +\pard\intbl\qc\fs18 17/46 (37.0%) \cell +\pard\intbl\qc\fs18 38/94 (40.4%) \cell +\pard\intbl\qc\fs18 28/60 (46.7%) \cell +\pard\intbl\qc\fs18 -2.9 (-21.8, 16.0) \cell +\pard\intbl\qc\fs18 -9.7 (-28.5, 9.1) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2835 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4366 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5897 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7428 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8959 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10830 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2835 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4366 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5897 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7428 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8959 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10830 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsflab05/tsflab05.rtf b/tests/testthat/_snaps/tsflab05/tsflab05.rtf old mode 100755 new mode 100644 index 6d3b58a6..536edf03 --- a/tests/testthat/_snaps/tsflab05/tsflab05.rtf +++ b/tests/testthat/_snaps/tsflab05/tsflab05.rtf @@ -3,30 +3,34 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2845 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4631 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6417 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8203 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10386 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2829 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4327 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5824 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7432 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8930 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10760 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB05:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2845 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4631 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6417 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8203 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10386 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2829 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4327 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5824 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7432 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8930 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10760 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell @@ -35,31 +39,35 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Category \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Laboratory Test \u8805? Grade 2, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \u8805? Grade 2, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -67,401 +75,361 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blood and lymphatic system disorders \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alanine Aminotransferase, high \cell +\pard\intbl\qc\fs18 14/49 (28.6%) \cell +\pard\intbl\qc\fs18 11/51 (21.6%) \cell +\pard\intbl\qc\fs18 25/100 (25.0%) \cell +\pard\intbl\qc\fs18 17/62 (27.4%) \cell +\pard\intbl\qc\fs18 1.2 (-15.7, 18.0) \cell +\pard\intbl\qc\fs18 -5.9 (-21.7, 10.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Anemia \cell -\pard\intbl\qc\fs18 28/53 (52.8%) \cell -\pard\intbl\qc\fs18 36/73 (49.3%) \cell -\pard\intbl\qc\fs18 33/59 (55.9%) \cell -\pard\intbl\qc\fs18 -3.1 (-21.6, 15.4) \cell -\pard\intbl\qc\fs18 -6.6 (-23.7, 10.5) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Albumin, low \cell +\pard\intbl\qc\fs18 16/49 (32.7%) \cell +\pard\intbl\qc\fs18 17/51 (33.3%) \cell +\pard\intbl\qc\fs18 33/100 (33.0%) \cell +\pard\intbl\qc\fs18 16/62 (25.8%) \cell +\pard\intbl\qc\fs18 6.8 (-10.2, 23.9) \cell +\pard\intbl\qc\fs18 7.5 (-9.4, 24.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Leukocytosis \cell -\pard\intbl\qc\fs18 0/53 \cell -\pard\intbl\qc\fs18 0/73 \cell -\pard\intbl\qc\fs18 0/59 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Aspartate Aminotransferase, high \cell +\pard\intbl\qc\fs18 8/49 (16.3%) \cell +\pard\intbl\qc\fs18 12/51 (23.5%) \cell +\pard\intbl\qc\fs18 20/100 (20.0%) \cell +\pard\intbl\qc\fs18 13/62 (21.0%) \cell +\pard\intbl\qc\fs18 -4.6 (-19.1, 9.8) \cell +\pard\intbl\qc\fs18 2.6 (-12.9, 18.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Bilirubin, high \cell +\pard\intbl\qc\fs18 9/49 (18.4%) \cell +\pard\intbl\qc\fs18 5/50 (10.0%) \cell +\pard\intbl\qc\fs18 14/99 (14.1%) \cell +\pard\intbl\qc\fs18 14/62 (22.6%) \cell +\pard\intbl\qc\fs18 -4.2 (-19.2, 10.8) \cell +\pard\intbl\qc\fs18 -12.6 (-25.9, 0.7) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Investigations \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Creatine Kinase, high \cell +\pard\intbl\qc\fs18 9/49 (18.4%) \cell +\pard\intbl\qc\fs18 6/51 (11.8%) \cell +\pard\intbl\qc\fs18 15/100 (15.0%) \cell +\pard\intbl\qc\fs18 12/62 (19.4%) \cell +\pard\intbl\qc\fs18 -1.0 (-15.6, 13.7) \cell +\pard\intbl\qc\fs18 -7.6 (-20.8, 5.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alanine aminotransferase increased \cell -\pard\intbl\qc\fs18 0/53 \cell -\pard\intbl\qc\fs18 0/73 \cell -\pard\intbl\qc\fs18 1/59 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Creatinine, high \cell +\pard\intbl\qc\fs18 10/49 (20.4%) \cell +\pard\intbl\qc\fs18 12/51 (23.5%) \cell +\pard\intbl\qc\fs18 22/100 (22.0%) \cell +\pard\intbl\qc\fs18 15/61 (24.6%) \cell +\pard\intbl\qc\fs18 -4.2 (-19.8, 11.4) \cell +\pard\intbl\qc\fs18 -1.1 (-16.9, 14.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alkaline phosphatase increased \cell -\pard\intbl\qc\fs18 0/53 \cell -\pard\intbl\qc\fs18 0/73 \cell -\pard\intbl\qc\fs18 1/59 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gamma Glutamyl Transferase, high \cell +\pard\intbl\qc\fs18 13/49 (26.5%) \cell +\pard\intbl\qc\fs18 9/51 (17.6%) \cell +\pard\intbl\qc\fs18 22/100 (22.0%) \cell +\pard\intbl\qc\fs18 13/62 (21.0%) \cell +\pard\intbl\qc\fs18 5.6 (-10.4, 21.5) \cell +\pard\intbl\qc\fs18 -3.3 (-17.9, 11.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Aspartate aminotransferase increased \cell -\pard\intbl\qc\fs18 1/53 (1.9%) \cell -\pard\intbl\qc\fs18 1/73 (1.4%) \cell -\pard\intbl\qc\fs18 1/59 (1.7%) \cell -\pard\intbl\qc\fs18 0.2 (-4.7, 5.1) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 3.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose, low \cell +\pard\intbl\qc\fs18 14/49 (28.6%) \cell +\pard\intbl\qc\fs18 11/51 (21.6%) \cell +\pard\intbl\qc\fs18 25/100 (25.0%) \cell +\pard\intbl\qc\fs18 24/62 (38.7%) \cell +\pard\intbl\qc\fs18 -10.1 (-27.7, 7.4) \cell +\pard\intbl\qc\fs18 -17.1 (-33.7, -0.6) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blood bilirubin increased \cell -\pard\intbl\qc\fs18 2/53 (3.8%) \cell -\pard\intbl\qc\fs18 1/73 (1.4%) \cell -\pard\intbl\qc\fs18 0/59 \cell -\pard\intbl\qc\fs18 3.8 (-1.4, 8.9) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, low \cell +\pard\intbl\qc\fs18 13/49 (26.5%) \cell +\pard\intbl\qc\fs18 25/51 (49.0%) \cell +\pard\intbl\qc\fs18 38/100 (38.0%) \cell +\pard\intbl\qc\fs18 18/62 (29.0%) \cell +\pard\intbl\qc\fs18 -2.5 (-19.2, 14.2) \cell +\pard\intbl\qc\fs18 20.0 (2.2, 37.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cholesterol high \cell -\pard\intbl\qc\fs18 2/53 (3.8%) \cell -\pard\intbl\qc\fs18 2/73 (2.7%) \cell -\pard\intbl\qc\fs18 3/59 (5.1%) \cell -\pard\intbl\qc\fs18 -1.3 (-8.9, 6.3) \cell -\pard\intbl\qc\fs18 -2.3 (-9.1, 4.4) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, high \cell +\pard\intbl\qc\fs18 13/49 (26.5%) \cell +\pard\intbl\qc\fs18 25/51 (49.0%) \cell +\pard\intbl\qc\fs18 38/100 (38.0%) \cell +\pard\intbl\qc\fs18 18/62 (29.0%) \cell +\pard\intbl\qc\fs18 -2.5 (-19.2, 14.2) \cell +\pard\intbl\qc\fs18 20.0 (2.2, 37.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Creatinine increased \cell -\pard\intbl\qc\fs18 0/53 \cell -\pard\intbl\qc\fs18 0/73 \cell -\pard\intbl\qc\fs18 0/59 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, low \cell +\pard\intbl\qc\fs18 14/49 (28.6%) \cell +\pard\intbl\qc\fs18 24/51 (47.1%) \cell +\pard\intbl\qc\fs18 38/100 (38.0%) \cell +\pard\intbl\qc\fs18 20/62 (32.3%) \cell +\pard\intbl\qc\fs18 -3.7 (-20.9, 13.5) \cell +\pard\intbl\qc\fs18 14.8 (-3.2, 32.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Platelet count decreased \cell -\pard\intbl\qc\fs18 26/53 (49.1%) \cell -\pard\intbl\qc\fs18 32/73 (43.8%) \cell -\pard\intbl\qc\fs18 24/59 (40.7%) \cell -\pard\intbl\qc\fs18 8.4 (-10.0, 26.8) \cell -\pard\intbl\qc\fs18 3.2 (-13.8, 20.1) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, high \cell +\pard\intbl\qc\fs18 14/49 (28.6%) \cell +\pard\intbl\qc\fs18 24/51 (47.1%) \cell +\pard\intbl\qc\fs18 38/100 (38.0%) \cell +\pard\intbl\qc\fs18 20/62 (32.3%) \cell +\pard\intbl\qc\fs18 -3.7 (-20.9, 13.5) \cell +\pard\intbl\qc\fs18 14.8 (-3.2, 32.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 White blood cell decreased \cell -\pard\intbl\qc\fs18 24/53 (45.3%) \cell -\pard\intbl\qc\fs18 25/73 (34.2%) \cell -\pard\intbl\qc\fs18 33/59 (55.9%) \cell -\pard\intbl\qc\fs18 -10.6 (-29.1, 7.8) \cell -\pard\intbl\qc\fs18 -21.7 (-38.4, -5.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Platelets, low \cell +\pard\intbl\qc\fs18 17/48 (35.4%) \cell +\pard\intbl\qc\fs18 13/51 (25.5%) \cell +\pard\intbl\qc\fs18 30/99 (30.3%) \cell +\pard\intbl\qc\fs18 17/62 (27.4%) \cell +\pard\intbl\qc\fs18 8.0 (-9.5, 25.5) \cell +\pard\intbl\qc\fs18 -1.9 (-18.2, 14.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium, low \cell +\pard\intbl\qc\fs18 15/49 (30.6%) \cell +\pard\intbl\qc\fs18 21/51 (41.2%) \cell +\pard\intbl\qc\fs18 36/100 (36.0%) \cell +\pard\intbl\qc\fs18 19/62 (30.6%) \cell +\pard\intbl\qc\fs18 0.0 (-17.3, 17.2) \cell +\pard\intbl\qc\fs18 10.5 (-7.2, 28.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutritional disorders \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium, high \cell +\pard\intbl\qc\fs18 15/49 (30.6%) \cell +\pard\intbl\qc\fs18 21/51 (41.2%) \cell +\pard\intbl\qc\fs18 36/100 (36.0%) \cell +\pard\intbl\qc\fs18 19/62 (30.6%) \cell +\pard\intbl\qc\fs18 0.0 (-17.3, 17.2) \cell +\pard\intbl\qc\fs18 10.5 (-7.2, 28.3) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CD4 lymphocytes decreased \cell -\pard\intbl\qc\fs18 23/53 (43.4%) \cell -\pard\intbl\qc\fs18 32/73 (43.8%) \cell -\pard\intbl\qc\fs18 34/59 (57.6%) \cell -\pard\intbl\qc\fs18 -14.2 (-32.6, 4.1) \cell -\pard\intbl\qc\fs18 -13.8 (-30.8, 3.2) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Urinary Protein, high \cell +\pard\intbl\qc\fs18 9/49 (18.4%) \cell +\pard\intbl\qc\fs18 11/51 (21.6%) \cell +\pard\intbl\qc\fs18 20/100 (20.0%) \cell +\pard\intbl\qc\fs18 12/62 (19.4%) \cell +\pard\intbl\qc\fs18 -1.0 (-15.6, 13.7) \cell +\pard\intbl\qc\fs18 2.2 (-12.8, 17.2) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperglycemia \cell -\pard\intbl\qc\fs18 4/53 (7.5%) \cell -\pard\intbl\qc\fs18 1/73 (1.4%) \cell -\pard\intbl\qc\fs18 0/59 \cell -\pard\intbl\qc\fs18 7.5 (0.4, 14.7) \cell -\pard\intbl\qc\fs18 1.4 (-1.3, 4.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 pH, low \cell +\pard\intbl\qc\fs18 15/46 (32.6%) \cell +\pard\intbl\qc\fs18 14/51 (27.5%) \cell +\pard\intbl\qc\fs18 29/97 (29.9%) \cell +\pard\intbl\qc\fs18 21/61 (34.4%) \cell +\pard\intbl\qc\fs18 -1.8 (-19.9, 16.2) \cell +\pard\intbl\qc\fs18 -7.0 (-24.1, 10.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperkalemia \cell -\pard\intbl\qc\fs18 0/53 \cell -\pard\intbl\qc\fs18 0/73 \cell -\pard\intbl\qc\fs18 1/59 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell -\pard\intbl\qc\fs18 -1.7 (-5.0, 1.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2829 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4327 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5824 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7432 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8930 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10760 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 pH, high \cell +\pard\intbl\qc\fs18 15/46 (32.6%) \cell +\pard\intbl\qc\fs18 14/51 (27.5%) \cell +\pard\intbl\qc\fs18 29/97 (29.9%) \cell +\pard\intbl\qc\fs18 21/61 (34.4%) \cell +\pard\intbl\qc\fs18 -1.8 (-19.9, 16.2) \cell +\pard\intbl\qc\fs18 -7.0 (-24.1, 10.1) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypernatremia \cell -\pard\intbl\qc\fs18 1/53 (1.9%) \cell -\pard\intbl\qc\fs18 0/73 \cell -\pard\intbl\qc\fs18 0/59 \cell -\pard\intbl\qc\fs18 1.9 (-1.8, 5.5) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoalbuminemia \cell -\pard\intbl\qc\fs18 29/53 (54.7%) \cell -\pard\intbl\qc\fs18 27/73 (37.0%) \cell -\pard\intbl\qc\fs18 33/59 (55.9%) \cell -\pard\intbl\qc\fs18 -1.2 (-19.7, 17.2) \cell -\pard\intbl\qc\fs18 -18.9 (-35.8, -2.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoglycemia \cell -\pard\intbl\qc\fs18 35/53 (66.0%) \cell -\pard\intbl\qc\fs18 32/73 (43.8%) \cell -\pard\intbl\qc\fs18 35/59 (59.3%) \cell -\pard\intbl\qc\fs18 6.7 (-11.2, 24.6) \cell -\pard\intbl\qc\fs18 -15.5 (-32.4, 1.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypokalemia \cell -\pard\intbl\qc\fs18 29/53 (54.7%) \cell -\pard\intbl\qc\fs18 32/73 (43.8%) \cell -\pard\intbl\qc\fs18 29/59 (49.2%) \cell -\pard\intbl\qc\fs18 5.6 (-12.9, 24.1) \cell -\pard\intbl\qc\fs18 -5.3 (-22.4, 11.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2845 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4631 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6417 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8203 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10386 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyponatremia \cell -\pard\intbl\qc\fs18 30/53 (56.6%) \cell -\pard\intbl\qc\fs18 37/73 (50.7%) \cell -\pard\intbl\qc\fs18 25/59 (42.4%) \cell -\pard\intbl\qc\fs18 14.2 (-4.1, 32.6) \cell -\pard\intbl\qc\fs18 8.3 (-8.7, 25.4) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2845 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4631 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6417 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8203 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10386 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2829 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4327 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5824 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7432 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8930 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10760 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2845 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4631 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6417 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8203 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10386 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2829 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4327 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5824 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7432 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8930 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10760 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell +\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsflab06/tsflab06.rtf b/tests/testthat/_snaps/tsflab06/tsflab06.rtf old mode 100755 new mode 100644 index aff7f38c..b37d9edb --- a/tests/testthat/_snaps/tsflab06/tsflab06.rtf +++ b/tests/testthat/_snaps/tsflab06/tsflab06.rtf @@ -56,8 +56,59864 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline High Dose \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Albumin (g/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 54 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 54 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 26 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Chloride (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Creatinine Kinase (U/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 43 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Phosphate (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 54 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 54 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Protein (g/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 54 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 54 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 17 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 16 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Creatinine (umol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 56 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Urate (umol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 54 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 54 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 25 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alanine Aminotransferase (U/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 56 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 43 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 26 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alkaline Phosphatase (U/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 56 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Aspartate Aminotransferase (U/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Bilirubin (umol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 25 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gamma Glutamyl Transferase (U/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 25 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 HDL Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 43 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 26 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 43 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 LDL Cholesterol (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 7 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 67 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 8 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 54 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 5 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 26 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 19 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 20 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Triglycerides (mmol/L) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 66 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 56 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 58 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 57 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 43 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 50 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 34 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 37 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 51 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 30 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -72,8 +59928,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\pard\intbl\qc\fs18 45 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -88,12 +59944,44 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 42 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \row } @@ -104,12 +59992,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell \row } @@ -120,7 +60008,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Calcium (mmol/L) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -136,7 +60024,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 16 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -152,8 +60040,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 52 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 28 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -170,10 +60058,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -187,9 +60075,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 26 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 26 \cell \row } @@ -203,9 +60091,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell \row } @@ -218,10 +60106,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 51 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 28 \cell \row } @@ -248,8 +60136,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 67 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 25 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -266,10 +60154,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -282,10 +60170,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 60 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell \row } @@ -300,8 +60188,8 @@ \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 2 \cell \row } @@ -314,10 +60202,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 62 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell \row } @@ -345,7 +60233,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 47 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -363,9 +60251,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \row } @@ -379,9 +60267,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 44 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 56 \cell +\pard\intbl\qc\fs18 45 \cell \row } @@ -396,8 +60284,8 @@ \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \row } @@ -411,9 +60299,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 57 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 47 \cell \row } @@ -440,23 +60328,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 20 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -472,8 +60344,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 52 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 21 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -507,9 +60379,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 20 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 20 \cell \row } @@ -523,9 +60395,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell \row } @@ -539,9 +60411,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 21 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 21 \cell \row } @@ -568,8 +60440,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 67 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -603,9 +60475,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 19 \cell \row } @@ -619,9 +60491,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -635,9 +60507,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 19 \cell \row } @@ -665,7 +60537,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 45 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -683,9 +60555,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \row } @@ -698,10 +60570,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 57 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 44 \cell \row } @@ -730,10 +60602,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 57 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 45 \cell \row } @@ -760,23 +60632,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potassium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 24 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -792,8 +60648,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 51 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -827,9 +60683,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 19 \cell \row } @@ -843,9 +60699,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -859,9 +60715,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 19 \cell \row } @@ -888,8 +60744,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 67 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -907,9 +60763,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -923,9 +60779,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 19 \cell \row } @@ -955,9 +60811,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 19 \cell \row } @@ -985,7 +60841,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 39 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1018,10 +60874,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 37 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 57 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 38 \cell \row } @@ -1050,10 +60906,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 57 \cell \pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 39 \cell \row } @@ -1080,23 +60936,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium (mmol/L) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2858 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5081 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 End of treatment \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1112,8 +60952,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 51 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1131,9 +60971,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -1147,9 +60987,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 48 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell \row } @@ -1163,9 +61003,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \row } @@ -1179,9 +61019,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 50 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell \row } @@ -1208,8 +61048,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6668 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 67 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1242,10 +61082,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 63 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 65 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell \row } @@ -1259,9 +61099,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -1274,10 +61114,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 65 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell \row } @@ -1305,7 +61145,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8891 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 38 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1322,10 +61162,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Low \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -1338,10 +61178,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10479 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Normal \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 35 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 52 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 36 \cell \row } @@ -1355,8 +61195,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 High \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 2 \cell \row } @@ -1371,9 +61211,9 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Total \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 54 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 38 \cell \row } diff --git a/tests/testthat/_snaps/tsflab07/tsflab07.rtf b/tests/testthat/_snaps/tsflab07/tsflab07.rtf old mode 100755 new mode 100644 index 1cd38d18..346387c8 --- a/tests/testthat/_snaps/tsflab07/tsflab07.rtf +++ b/tests/testthat/_snaps/tsflab07/tsflab07.rtf @@ -3,13 +3,13 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2687 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4397 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6107 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7328 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8549 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9770 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10992 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3332 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4789 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6247 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7704 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9162 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10203 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11244 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB07:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -23,14 +23,14 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2687 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4397 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6107 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7328 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8549 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9770 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10992 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr NCI-CTCAE Category \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3332 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4789 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6247 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7704 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9162 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10203 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11244 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Baseline Toxicity Grade \cell \pard\intbl\qc\fs18 \keepn\trhdr Baseline Toxicity Grade \cell @@ -43,14 +43,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4397 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6107 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7328 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8549 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9770 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10992 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Laboratory Test \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4789 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6247 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7704 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9162 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10203 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11244 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell \pard\intbl\qc\fs18 \keepn\trhdr N \cell \pard\intbl\qc\fs18 \keepn\trhdr Grade 0 \cell \pard\intbl\qc\fs18 \keepn\trhdr Grade 1 \cell @@ -63,15 +63,15 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 67 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -83,15 +83,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -103,15 +103,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 64 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -123,13 +123,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -143,34 +143,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blood and lymphatic system disorders \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Leukocytosis \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alanine Aminotransferase, high \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -183,15 +163,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 49 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -203,14 +183,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -223,94 +203,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 33 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -323,33 +303,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -363,15 +343,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -383,14 +363,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -403,94 +383,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 20 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 14 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 12 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -503,33 +483,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -543,14 +523,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell \pard\intbl\qc\fs18 59 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -563,14 +543,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -583,94 +563,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 26 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 15 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -683,19 +663,19 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 59 \cell \row @@ -703,13 +683,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -723,34 +703,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Investigations \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alanine aminotransferase increased \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Aspartate Aminotransferase, high \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -763,15 +723,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 45 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -783,14 +743,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -803,94 +763,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 49 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 20 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 8 \cell \pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -903,33 +863,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 49 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 7 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 45 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -943,15 +903,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 48 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -963,14 +923,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -983,94 +943,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 70 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 71 \cell +\pard\intbl\qc\fs18 26 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 11 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 8 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -1083,33 +1043,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 70 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1123,15 +1083,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 58 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1143,14 +1103,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1163,94 +1123,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 34 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 17 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -1263,33 +1223,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 57 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 58 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1303,14 +1263,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alkaline phosphatase increased \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Bilirubin, high \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1323,15 +1283,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 46 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1343,14 +1303,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1363,94 +1323,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 27 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 11 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -1463,33 +1423,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 46 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1503,15 +1463,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 48 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1523,14 +1483,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1543,94 +1503,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 70 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 71 \cell +\pard\intbl\qc\fs18 24 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 20 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -1643,33 +1603,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 70 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 13 \cell \pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1683,14 +1643,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell \pard\intbl\qc\fs18 59 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1703,14 +1663,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1723,94 +1683,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 32 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -1823,19 +1783,19 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 59 \cell \row @@ -1843,13 +1803,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1863,14 +1823,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Aspartate aminotransferase increased \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Creatinine, high \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1883,15 +1843,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1903,14 +1863,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1923,94 +1883,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 20 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 13 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 9 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -2023,33 +1983,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 50 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 47 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2063,15 +2023,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2083,14 +2043,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2103,38 +2063,38 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 66 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 70 \cell +\pard\intbl\qc\fs18 27 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 6 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 13 \cell @@ -2143,54 +2103,54 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 9 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -2203,33 +2163,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 14 \cell \pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 51 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2243,15 +2203,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 57 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2263,14 +2223,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2283,94 +2243,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 57 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 25 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 10 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -2383,33 +2343,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 11 \cell \pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 57 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2423,14 +2383,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blood bilirubin increased \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Glucose, low \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2443,15 +2403,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 49 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2463,14 +2423,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2483,74 +2443,74 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -2563,14 +2523,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -2583,33 +2543,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2623,15 +2583,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 51 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2643,14 +2603,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2663,74 +2623,74 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 70 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 51 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -2743,14 +2703,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -2763,33 +2723,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 70 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 51 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2803,15 +2763,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2823,14 +2783,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2843,54 +2803,54 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 61 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -2903,14 +2863,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -2923,14 +2883,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -2943,2273 +2903,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cholesterol high \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 57 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 58 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 57 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Creatinine increased \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 49 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 50 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 42 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 46 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 49 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 68 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 70 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 41 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 46 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 68 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 58 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 40 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 41 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 58 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Platelet count decreased \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 52 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 43 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 44 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 38 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 38 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 10 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 52 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 72 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 67 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 69 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 48 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 49 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 35 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 36 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 25 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 70 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 72 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 52 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 52 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 37 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 37 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 22 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 22 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 White blood cell decreased \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 45 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 45 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 33 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 18 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 67 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 70 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 50 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 32 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 33 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 21 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 21 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 70 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 52 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 52 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 42 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 42 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 21 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell \pard\intbl\qc\fs18 21 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 4 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 61 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5223,34 +2943,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutritional disorders \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CD4 lymphocytes decreased \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, low \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5263,15 +2963,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 51 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 48 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5283,14 +2983,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5303,133 +3003,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 47 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 28 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 15 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5443,15 +3143,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 72 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 48 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5463,14 +3163,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5483,133 +3183,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 66 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 68 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 46 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 37 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 70 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 72 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5623,15 +3323,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 57 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 61 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5643,14 +3343,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5663,133 +3363,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 56 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 60 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 43 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 27 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 56 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 61 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5803,14 +3503,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperglycemia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, high \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5823,15 +3523,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 37 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5843,14 +3543,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -5863,94 +3563,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 15 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 6 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 15 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -5963,33 +3663,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 37 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6003,15 +3703,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 40 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6023,14 +3723,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6043,94 +3743,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 8 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 21 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -6143,33 +3843,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 40 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6183,15 +3883,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 40 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6203,14 +3903,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6223,94 +3923,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 2 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 10 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 22 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -6323,33 +4023,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 40 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6363,14 +4063,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperkalemia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, low \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6383,15 +4083,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 48 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6403,14 +4103,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6423,34 +4123,34 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 47 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell @@ -6463,34 +4163,34 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -6503,14 +4203,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -6523,33 +4223,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6563,15 +4263,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6583,14 +4283,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6603,34 +4303,34 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -6643,14 +4343,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -6663,14 +4363,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -6683,14 +4383,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -6703,33 +4403,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6743,15 +4443,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 58 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6763,14 +4463,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6783,74 +4483,74 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 58 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 57 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -6863,14 +4563,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -6883,33 +4583,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 58 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 58 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6923,14 +4623,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypernatremia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, high \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6943,15 +4643,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 39 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6963,14 +4663,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -6983,94 +4683,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 13 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -7083,33 +4783,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 39 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7123,15 +4823,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 39 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7143,14 +4843,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7163,94 +4863,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 15 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 22 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -7263,33 +4963,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 39 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7303,15 +5003,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 43 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7323,14 +5023,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7343,94 +5043,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 56 \cell -\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 4 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 15 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 24 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -7443,33 +5143,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 56 \cell -\pard\intbl\qc\fs18 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 43 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7483,14 +5183,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoalbuminemia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Platelets, low \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7503,15 +5203,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 47 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7523,14 +5223,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7543,133 +5243,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 45 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 2 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 34 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 23 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 47 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7683,15 +5383,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 48 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7703,14 +5403,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7723,133 +5423,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 69 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 22 \cell \pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 71 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 50 \cell -\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 41 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 19 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 71 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 22 \cell \pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7863,15 +5563,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 57 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7883,14 +5583,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -7903,133 +5603,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 57 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 49 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 40 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 21 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 57 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8043,14 +5743,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoglycemia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium, low \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8063,15 +5763,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 49 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8083,14 +5783,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8103,133 +5803,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 41 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 38 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 21 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8243,15 +5943,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8263,14 +5963,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8283,133 +5983,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 69 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 70 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 50 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 35 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 25 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 72 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8423,14 +6123,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell \pard\intbl\qc\fs18 59 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8443,14 +6143,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8463,19 +6163,19 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 58 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 58 \cell \row @@ -8483,99 +6183,99 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 55 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 37 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 23 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 32 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 59 \cell \row @@ -8583,13 +6283,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8603,14 +6303,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypokalemia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Sodium, high \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8623,15 +6323,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 41 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8643,14 +6343,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8663,133 +6363,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 45 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 7 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 38 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 16 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 25 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 12 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 41 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8803,15 +6503,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 37 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8823,14 +6523,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8843,133 +6543,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 71 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 71 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 49 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 38 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 8 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 17 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 23 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 15 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 37 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -8983,15 +6683,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 39 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9003,14 +6703,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9023,133 +6723,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 57 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 6 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 38 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 14 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 28 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 19 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 59 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 39 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9163,14 +6863,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyponatremia \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Urinary Protein, high \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9183,15 +6883,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline High Dose \cell -\pard\intbl\qc\fs18 53 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 48 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9203,14 +6903,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9223,133 +6923,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 24 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 47 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 2 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 14 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 36 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 9 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 21 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 1 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 5 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 48 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9363,15 +7063,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 73 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Xanomeline High Dose \cell +\pard\intbl\qc\fs18 49 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9383,14 +7083,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9403,133 +7103,133 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 64 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 6 \cell \pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 31 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 52 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 3 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 8 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 8 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 28 \cell -\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 2 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 2 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 73 \cell +\pard\intbl\qc\fs18 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9543,15 +7243,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Placebo \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Placebo \cell +\pard\intbl\qc\fs18 60 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9563,14 +7263,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Worst toxicity grade, n \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Worst toxicity grade, n \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -9583,94 +7283,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 0 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 7 \cell +\pard\intbl\qc\fs18 7 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 34 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 1 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 1 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 50 \cell +\pard\intbl\qc\fs18 8 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 12 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 2 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 2 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 39 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 9 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 3 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 3 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 25 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 \cell +\pard\intbl\qc\fs18 3 \cell +\pard\intbl\qc\fs18 1 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 25 \cell +\pard\intbl\qc\fs18 5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Grade 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Grade 4 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell @@ -9683,33 +7383,33 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2687 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4397 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6107 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7328 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8549 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9770 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10992 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li1167\fi-87 Total \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3332 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4789 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6247 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7704 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9162 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10203 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11244 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Total \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 58 \cell -\pard\intbl\qc\fs18 1 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 10 \cell +\pard\intbl\qc\fs18 4 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 60 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2687 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4397 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6107 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7328 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8549 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9770 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10992 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3332 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4789 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6247 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7704 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9162 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10203 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11244 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -9723,13 +7423,13 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2687 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4397 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6107 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7328 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8549 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9770 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10992 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3332 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6247 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7704 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9162 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10203 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11244 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsflab08/tsflab08.rtf b/tests/testthat/_snaps/tsflab08/tsflab08.rtf new file mode 100644 index 00000000..9d89f723 --- /dev/null +++ b/tests/testthat/_snaps/tsflab08/tsflab08.rtf @@ -0,0 +1,242 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3424 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5743 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8063 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10382 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB08:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3424 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5743 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8063 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10382 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Quadrant, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with on-treatment ALT or AST and TBILI values \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 99 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Potential Hy's Law (right upper quadrant) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ALT or AST \u8805?3x ULN and TBILI \u8805?2x ULN \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 TBILI \u8805?2x ULN within 30 days on or after ALT or AST \u8805?3x ULN\super a\nosupersub \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cholestasis (left upper quadrant) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ALT and AST <3x ULN and TBILI \u8805?2x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Temple's Corollary (right lower quadrant) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ALT or AST \u8805?3x ULN and TBILI <2x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Normal or near normal (left lower quadrant) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 ALT and AST <3x ULN and TBILI <2x ULN \cell +\pard\intbl\qc\fs18 47 (97.9%) \cell +\pard\intbl\qc\fs18 48 (94.1%) \cell +\pard\intbl\qc\fs18 95 (96.0%) \cell +\pard\intbl\qc\fs18 59 (95.2%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3424 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5743 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8063 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10382 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab09/tsflab09.rtf b/tests/testthat/_snaps/tsflab09/tsflab09.rtf new file mode 100644 index 00000000..f897aea8 --- /dev/null +++ b/tests/testthat/_snaps/tsflab09/tsflab09.rtf @@ -0,0 +1,186 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3424 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5743 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8063 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10382 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB09:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3424 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5743 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8063 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10382 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Quadrant, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with on-treatment ALP and TBILI values \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 99 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 TBILI \u8805?2x ULN and ALP \u8805?2x ULN (right upper quadrant) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 TBILI \u8805?2x ULN within 30 days on or after ALP \u8805?2x ULN\super a\nosupersub \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 TBILI \u8805?2x ULN and ALP <2x ULN (left upper quadrant) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (4.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 TBILI <2x ULN and ALP \u8805?2x ULN (right lower quadrant) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3424 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5743 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8063 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10382 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 TBILI <2x ULN and ALP <2x ULN (left lower quadrant) \cell +\pard\intbl\qc\fs18 47 (97.9%) \cell +\pard\intbl\qc\fs18 47 (92.2%) \cell +\pard\intbl\qc\fs18 94 (94.9%) \cell +\pard\intbl\qc\fs18 58 (93.5%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3424 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5743 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8063 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10382 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3424 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5743 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8063 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10382 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsflab10/tsflab10.rtf b/tests/testthat/_snaps/tsflab10/tsflab10.rtf new file mode 100644 index 00000000..c501b7d5 --- /dev/null +++ b/tests/testthat/_snaps/tsflab10/tsflab10.rtf @@ -0,0 +1,1446 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3415 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5736 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8058 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10380 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB10:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3415 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5736 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8058 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10380 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr (N=67) \cell +\pard\intbl\qc\fs18 \keepn\trhdr (N=51) \cell +\pard\intbl\qc\fs18 \keepn\trhdr (N=118) \cell +\pard\intbl\qc\fs18 \keepn\trhdr (N=64) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ALT or AST \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Any on-treatment value \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 114 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.6%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN and <5x ULN \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.6%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN and <8x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 8x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 10x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 20x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (4.1%) \cell +\pard\intbl\qc\fs18 3 (2.7%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN and <5x ULN \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (4.1%) \cell +\pard\intbl\qc\fs18 3 (2.7%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN and <8x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 8x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 10x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 20x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN and <5x ULN \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN and <8x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 8x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 10x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 20x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN and <5x ULN \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN and <8x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 8x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 10x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 20x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 3 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN and <5x ULN \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 3 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN and <8x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 8x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 10x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 20x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 TBILI \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Any on-treatment value \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 113 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 2x ULN \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.7%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.7%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 2x ULN \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (4.1%) \cell +\pard\intbl\qc\fs18 3 (2.7%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (4.1%) \cell +\pard\intbl\qc\fs18 3 (2.7%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 97 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 2x ULN \cell +\pard\intbl\qc\fs18 1 (2.2%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 1 (2.2%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 46 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 53 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 2x ULN \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 2x ULN \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 3 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 3 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 ALP \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Any on-treatment value \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 114 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 1.5x ULN \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.8%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 2x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.9%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.9%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 61 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 1.5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.9%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 2x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.9%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.9%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 1.5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 2x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 89 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 1.5x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 2x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 1 (1.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 1.5x ULN \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (2.6%) \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 2x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (1.3%) \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3415 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5736 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8058 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10380 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805? 3x ULN \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (1.3%) \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3415 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5736 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8058 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10380 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3415 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5736 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8058 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10380 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit01/tsfvit01.rtf b/tests/testthat/_snaps/tsfvit01/tsfvit01.rtf new file mode 100644 index 00000000..4a52f36d --- /dev/null +++ b/tests/testthat/_snaps/tsfvit01/tsfvit01.rtf @@ -0,0 +1,1072 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6110 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9406 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT01:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2814 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6110 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9406 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systolic Blood Pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 63 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 137.13 (16.318) \cell +\pard\intbl\qc\fs18 137.44 (17.291) \cell +\pard\intbl\qc\fs18 136.77 (17.742) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 136.67 (103.3, 181.3) \cell +\pard\intbl\qc\fs18 138.00 (100.0, 179.3) \cell +\pard\intbl\qc\fs18 136.00 (86.7, 181.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 135.01 (16.886) \cell +\pard\intbl\qc\fs18 131.45 (15.022) \cell +\pard\intbl\qc\fs18 133.55 (16.122) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 132.67 (96.7, 173.3) \cell +\pard\intbl\qc\fs18 132.00 (104.0, 178.3) \cell +\pard\intbl\qc\fs18 131.67 (92.7, 166.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 136.78 (16.193) \cell +\pard\intbl\qc\fs18 137.44 (17.291) \cell +\pard\intbl\qc\fs18 137.04 (17.753) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -1.78 (12.838) \cell +\pard\intbl\qc\fs18 -5.99 (16.215) \cell +\pard\intbl\qc\fs18 -3.64 (13.079) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.33 (-27.3, 26.0) \cell +\pard\intbl\qc\fs18 -5.33 (-49.3, 31.7) \cell +\pard\intbl\qc\fs18 -2.33 (-32.0, 35.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 1.86 (-2.70, 6.42) \cell +\pard\intbl\qc\fs18 -2.35 (-7.95, 3.25) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 137.31 (18.100) \cell +\pard\intbl\qc\fs18 132.20 (15.564) \cell +\pard\intbl\qc\fs18 134.21 (17.226) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 139.33 (102.7, 176.0) \cell +\pard\intbl\qc\fs18 132.00 (104.7, 173.0) \cell +\pard\intbl\qc\fs18 134.00 (91.3, 180.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 136.61 (17.185) \cell +\pard\intbl\qc\fs18 137.44 (17.291) \cell +\pard\intbl\qc\fs18 136.94 (17.886) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 0.70 (16.175) \cell +\pard\intbl\qc\fs18 -5.25 (15.075) \cell +\pard\intbl\qc\fs18 -2.83 (14.279) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 3.33 (-32.7, 59.3) \cell +\pard\intbl\qc\fs18 -6.00 (-50.0, 39.0) \cell +\pard\intbl\qc\fs18 -1.67 (-37.3, 36.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 3.54 (-2.41, 9.48) \cell +\pard\intbl\qc\fs18 -2.42 (-7.97, 3.14) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 134.57 (17.211) \cell +\pard\intbl\qc\fs18 130.30 (15.997) \cell +\pard\intbl\qc\fs18 134.12 (19.101) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 132.33 (101.3, 169.3) \cell +\pard\intbl\qc\fs18 129.33 (97.3, 164.0) \cell +\pard\intbl\qc\fs18 131.33 (88.0, 203.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 136.13 (17.839) \cell +\pard\intbl\qc\fs18 138.70 (16.858) \cell +\pard\intbl\qc\fs18 135.96 (18.361) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -1.56 (11.701) \cell +\pard\intbl\qc\fs18 -8.40 (15.788) \cell +\pard\intbl\qc\fs18 -2.01 (15.994) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.67 (-28.3, 22.0) \cell +\pard\intbl\qc\fs18 -8.33 (-48.7, 38.0) \cell +\pard\intbl\qc\fs18 -2.00 (-38.7, 48.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.45 (-5.17, 6.06) \cell +\pard\intbl\qc\fs18 -6.38 (-12.67, -0.10) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Diastolic Blood Pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 63 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 76.169 (9.2561) \cell +\pard\intbl\qc\fs18 78.458 (10.1546) \cell +\pard\intbl\qc\fs18 76.016 (10.7691) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 76.000 (57.33, 99.33) \cell +\pard\intbl\qc\fs18 78.667 (53.00, 102.00) \cell +\pard\intbl\qc\fs18 76.000 (47.33, 103.33) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 75.823 (9.1475) \cell +\pard\intbl\qc\fs18 76.739 (9.0348) \cell +\pard\intbl\qc\fs18 74.333 (9.3975) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 75.833 (59.33, 100.67) \cell +\pard\intbl\qc\fs18 75.667 (52.67, 92.33) \cell +\pard\intbl\qc\fs18 74.000 (53.33, 96.67) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 76.182 (9.3264) \cell +\pard\intbl\qc\fs18 78.458 (10.1546) \cell +\pard\intbl\qc\fs18 76.060 (10.9415) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.359 (7.2532) \cell +\pard\intbl\qc\fs18 -1.719 (9.5257) \cell +\pard\intbl\qc\fs18 -1.617 (7.8827) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 0.000 (-22.00, 16.67) \cell +\pard\intbl\qc\fs18 -1.333 (-33.33, 16.33) \cell +\pard\intbl\qc\fs18 -1.333 (-20.67, 21.67) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 1.259 (-1.409, 3.926) \cell +\pard\intbl\qc\fs18 -0.101 (-3.421, 3.218) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 76.043 (9.1164) \cell +\pard\intbl\qc\fs18 77.366 (8.5897) \cell +\pard\intbl\qc\fs18 75.486 (11.4555) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 75.333 (56.00, 97.33) \cell +\pard\intbl\qc\fs18 79.000 (56.67, 90.67) \cell +\pard\intbl\qc\fs18 75.000 (43.33, 98.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 60 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 76.511 (10.0173) \cell +\pard\intbl\qc\fs18 78.458 (10.1546) \cell +\pard\intbl\qc\fs18 76.117 (11.0249) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.468 (8.0912) \cell +\pard\intbl\qc\fs18 -1.092 (11.1609) \cell +\pard\intbl\qc\fs18 -0.544 (9.2170) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -1.333 (-20.33, 16.67) \cell +\pard\intbl\qc\fs18 0.000 (-29.33, 22.00) \cell +\pard\intbl\qc\fs18 -0.667 (-22.00, 30.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 0.076 (-3.247, 3.400) \cell +\pard\intbl\qc\fs18 -0.547 (-4.446, 3.351) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 75.405 (8.7326) \cell +\pard\intbl\qc\fs18 76.213 (9.5802) \cell +\pard\intbl\qc\fs18 74.358 (9.5370) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 75.333 (56.67, 98.67) \cell +\pard\intbl\qc\fs18 77.333 (53.00, 96.00) \cell +\pard\intbl\qc\fs18 74.667 (51.33, 103.33) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Change from baseline to Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 54 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Baseline mean (SD) \cell +\pard\intbl\qc\fs18 75.698 (9.7888) \cell +\pard\intbl\qc\fs18 78.887 (10.3877) \cell +\pard\intbl\qc\fs18 76.611 (11.3101) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 -0.294 (7.2408) \cell +\pard\intbl\qc\fs18 -2.674 (9.3448) \cell +\pard\intbl\qc\fs18 -2.074 (8.1443) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Median (min, max) \cell +\pard\intbl\qc\fs18 -0.333 (-18.67, 18.67) \cell +\pard\intbl\qc\fs18 -2.667 (-24.67, 15.00) \cell +\pard\intbl\qc\fs18 -2.000 (-20.00, 16.00) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6110 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9406 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Difference in mean vs. placebo (95% CI) \cell +\pard\intbl\qc\fs18 1.780 (-1.345, 4.906) \cell +\pard\intbl\qc\fs18 -0.600 (-4.089, 2.889) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6110 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9406 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6110 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9406 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit01apart1/tsfvit01apart1of4.rtf b/tests/testthat/_snaps/tsfvit01apart1/tsfvit01apart1of4.rtf deleted file mode 100644 index 47039c4f..00000000 --- a/tests/testthat/_snaps/tsfvit01apart1/tsfvit01apart1of4.rtf +++ /dev/null @@ -1,580 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4788 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8778 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT01apart1of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2860 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4788 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8778 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4788 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8778 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Blood Pressure \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2860 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4788 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8778 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 127.37500 (112.23883, 142.51117) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 128.58333 (119.89675, 137.26992) \cell -\pard\intbl\qc\fs18 1.20833 (-11.68998, 14.10664) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 122.04167 (110.93616, 133.14717) \cell -\pard\intbl\qc\fs18 -5.33333 (-21.55806, 10.89140) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 123.12500 (115.85818, 130.39182) \cell -\pard\intbl\qc\fs18 -4.25000 (-21.93755, 13.43755) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 78.83333 (72.67723, 84.98944) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 78.58333 (72.77448, 84.39219) \cell -\pard\intbl\qc\fs18 -0.25000 (-6.99885, 6.49885) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 77.08333 (68.41464, 85.75202) \cell -\pard\intbl\qc\fs18 -1.75000 (-11.08542, 7.58542) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 8/8 (100.0%) \cell -\pard\intbl\qc\fs18 77.16667 (72.03466, 82.29867) \cell -\pard\intbl\qc\fs18 -1.66667 (-9.65639, 6.32306) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 134.91667 (127.98187, 141.85146) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 132.47917 (125.54787, 139.41047) \cell -\pard\intbl\qc\fs18 -2.43750 (-9.39870, 4.52370) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 131.72917 (125.68929, 137.76905) \cell -\pard\intbl\qc\fs18 -3.18750 (-9.69885, 3.32385) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 15/15 (100.0%) \cell -\pard\intbl\qc\fs18 132.95556 (125.34652, 140.56459) \cell -\pard\intbl\qc\fs18 -3.82222 (-11.21911, 3.57466) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 77.04167 (73.06948, 81.01385) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 79.60417 (74.66634, 84.54199) \cell -\pard\intbl\qc\fs18 2.56250 (-1.25020, 6.37520) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 16/16 (100.0%) \cell -\pard\intbl\qc\fs18 78.60417 (73.92755, 83.28079) \cell -\pard\intbl\qc\fs18 1.56250 (-3.73593, 6.86093) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 15/15 (100.0%) \cell -\pard\intbl\qc\fs18 74.91111 (68.41783, 81.40439) \cell -\pard\intbl\qc\fs18 -2.44444 (-6.48849, 1.59960) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 143.06897 (136.39381, 149.74412) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 132.16092 (125.57485, 138.74699) \cell -\pard\intbl\qc\fs18 -10.90805 (-16.78895, -5.02714) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 132.59770 (126.15586, 139.03955) \cell -\pard\intbl\qc\fs18 -10.47126 (-15.74485, -5.19768) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 28/28 (100.0%) \cell -\pard\intbl\qc\fs18 130.28571 (124.11158, 136.45985) \cell -\pard\intbl\qc\fs18 -13.10714 (-18.37720, -7.83709) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 80.73563 (76.43408, 85.03719) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 75.32184 (71.63105, 79.01263) \cell -\pard\intbl\qc\fs18 -5.41379 (-9.35848, -1.46911) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 29/29 (100.0%) \cell -\pard\intbl\qc\fs18 74.31034 (71.05598, 77.56471) \cell -\pard\intbl\qc\fs18 -6.42529 (-9.94658, -2.90400) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4788 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8778 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 28/28 (100.0%) \cell -\pard\intbl\qc\fs18 75.00000 (71.32004, 78.67996) \cell -\pard\intbl\qc\fs18 -5.97619 (-9.52099, -2.43139) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2860 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4788 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8778 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2860 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4788 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8778 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit01apart2/tsfvit01apart2of4.rtf b/tests/testthat/_snaps/tsfvit01apart2/tsfvit01apart2of4.rtf deleted file mode 100644 index f715199e..00000000 --- a/tests/testthat/_snaps/tsfvit01apart2/tsfvit01apart2of4.rtf +++ /dev/null @@ -1,580 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4797 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8851 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT01apart2of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2838 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4797 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8851 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4797 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8851 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Blood Pressure \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4797 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8851 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 134.20000 (119.12402, 149.27598) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 135.13333 (121.48883, 148.77783) \cell -\pard\intbl\qc\fs18 0.93333 (-15.30722, 17.17389) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 143.66667 (130.18509, 157.14824) \cell -\pard\intbl\qc\fs18 9.46667 (-5.73097, 24.66430) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 3/3 (100.0%) \cell -\pard\intbl\qc\fs18 126.77778 (80.73118, 172.82438) \cell -\pard\intbl\qc\fs18 -2.55556 (-30.19708, 25.08597) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 84.26667 (72.01181, 96.52153) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 86.66667 (75.87379, 97.45955) \cell -\pard\intbl\qc\fs18 2.40000 (-4.25704, 9.05704) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 78.86667 (69.47588, 88.25746) \cell -\pard\intbl\qc\fs18 -5.40000 (-16.28927, 5.48927) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 3/3 (100.0%) \cell -\pard\intbl\qc\fs18 73.11111 (51.49716, 94.72507) \cell -\pard\intbl\qc\fs18 -4.33333 (-15.53493, 6.86826) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 17 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 131.41176 (122.61808, 140.20545) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 132.54902 (123.93730, 141.16074) \cell -\pard\intbl\qc\fs18 1.13725 (-3.59953, 5.87404) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 10/10 (100.0%) \cell -\pard\intbl\qc\fs18 132.40000 (123.24324, 141.55676) \cell -\pard\intbl\qc\fs18 3.90000 (-1.69903, 9.49903) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 9/9 (100.0%) \cell -\pard\intbl\qc\fs18 135.70370 (128.27055, 143.13686) \cell -\pard\intbl\qc\fs18 6.74074 (1.81423, 11.66725) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 74.13725 (70.12248, 78.15203) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 17/17 (100.0%) \cell -\pard\intbl\qc\fs18 78.31373 (72.85982, 83.76763) \cell -\pard\intbl\qc\fs18 4.17647 (0.53878, 7.81416) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 10/10 (100.0%) \cell -\pard\intbl\qc\fs18 78.76667 (71.30019, 86.23314) \cell -\pard\intbl\qc\fs18 4.03333 (-1.01306, 9.07973) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 9/9 (100.0%) \cell -\pard\intbl\qc\fs18 78.85185 (74.76610, 82.93760) \cell -\pard\intbl\qc\fs18 3.96296 (-0.00734, 7.93327) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 141.62092 (136.44665, 146.79518) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 49/49 (100.0%) \cell -\pard\intbl\qc\fs18 136.29932 (131.13591, 141.46273) \cell -\pard\intbl\qc\fs18 -4.97959 (-9.07262, -0.88656) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 38/38 (100.0%) \cell -\pard\intbl\qc\fs18 138.23684 (131.80445, 144.66924) \cell -\pard\intbl\qc\fs18 -2.45614 (-7.80728, 2.89499) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 35/35 (100.0%) \cell -\pard\intbl\qc\fs18 136.58095 (129.40991, 143.75199) \cell -\pard\intbl\qc\fs18 -2.42857 (-6.65424, 1.79710) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 76.70588 (74.11246, 79.29930) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 49/49 (100.0%) \cell -\pard\intbl\qc\fs18 75.17007 (72.50558, 77.83456) \cell -\pard\intbl\qc\fs18 -1.37415 (-3.38731, 0.63901) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 38/38 (100.0%) \cell -\pard\intbl\qc\fs18 76.08772 (73.07524, 79.10020) \cell -\pard\intbl\qc\fs18 -0.05263 (-2.60383, 2.49856) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 35/35 (100.0%) \cell -\pard\intbl\qc\fs18 74.41905 (71.11597, 77.72212) \cell -\pard\intbl\qc\fs18 -1.34286 (-3.41130, 0.72559) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4797 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8851 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit01apart3/tsfvit01apart3of4.rtf b/tests/testthat/_snaps/tsfvit01apart3/tsfvit01apart3of4.rtf deleted file mode 100644 index 280c0101..00000000 --- a/tests/testthat/_snaps/tsfvit01apart3/tsfvit01apart3of4.rtf +++ /dev/null @@ -1,580 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4797 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8851 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT01apart3of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4797 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8851 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4797 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8851 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Blood Pressure \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4797 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8851 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 133.42857 (118.20191, 148.65524) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 133.71429 (117.62009, 149.80848) \cell -\pard\intbl\qc\fs18 0.28571 (-8.77489, 9.34632) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 133.38095 (116.27531, 150.48660) \cell -\pard\intbl\qc\fs18 -0.04762 (-3.26336, 3.16813) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 129.20000 (120.67451, 137.72549) \cell -\pard\intbl\qc\fs18 -0.73333 (-20.91308, 19.44641) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 76.57143 (64.96169, 88.18117) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 76.80952 (66.10387, 87.51518) \cell -\pard\intbl\qc\fs18 0.23810 (-7.24309, 7.71928) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 7/7 (100.0%) \cell -\pard\intbl\qc\fs18 75.61905 (59.61763, 91.62046) \cell -\pard\intbl\qc\fs18 -0.95238 (-7.54373, 5.63896) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 5/5 (100.0%) \cell -\pard\intbl\qc\fs18 74.26667 (53.96842, 94.56491) \cell -\pard\intbl\qc\fs18 -2.06667 (-15.88830, 11.75496) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 19 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 130.73684 (120.77229, 140.70139) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 125.15789 (116.80566, 133.51013) \cell -\pard\intbl\qc\fs18 -5.57895 (-12.62079, 1.46289) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 126.66667 (118.88144, 134.45189) \cell -\pard\intbl\qc\fs18 -4.07018 (-10.31295, 2.17260) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 132.82456 (121.70851, 143.94061) \cell -\pard\intbl\qc\fs18 2.08772 (-2.28040, 6.45584) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 77.33333 (71.84962, 82.81705) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 74.05263 (70.58225, 77.52301) \cell -\pard\intbl\qc\fs18 -3.28070 (-8.25552, 1.69412) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 73.85965 (69.69989, 78.01941) \cell -\pard\intbl\qc\fs18 -3.47368 (-8.62748, 1.68011) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 19/19 (100.0%) \cell -\pard\intbl\qc\fs18 75.70175 (71.23526, 80.16825) \cell -\pard\intbl\qc\fs18 -1.63158 (-4.93802, 1.67486) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 33 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 33/33 (100.0%) \cell -\pard\intbl\qc\fs18 139.15152 (133.35446, 144.94857) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 32/32 (100.0%) \cell -\pard\intbl\qc\fs18 134.59375 (128.37103, 140.81647) \cell -\pard\intbl\qc\fs18 -4.40625 (-8.77864, -0.03386) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 30/30 (100.0%) \cell -\pard\intbl\qc\fs18 133.84444 (126.72385, 140.96503) \cell -\pard\intbl\qc\fs18 -4.96667 (-10.64927, 0.71594) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 27/27 (100.0%) \cell -\pard\intbl\qc\fs18 131.24691 (124.82089, 137.67294) \cell -\pard\intbl\qc\fs18 -6.18519 (-11.63114, -0.73923) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 33/33 (100.0%) \cell -\pard\intbl\qc\fs18 75.57576 (72.12017, 79.03135) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 32/32 (100.0%) \cell -\pard\intbl\qc\fs18 72.95833 (68.91098, 77.00568) \cell -\pard\intbl\qc\fs18 -2.60417 (-6.04063, 0.83230) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 30/30 (100.0%) \cell -\pard\intbl\qc\fs18 74.26667 (69.88594, 78.64739) \cell -\pard\intbl\qc\fs18 -0.86667 (-4.07027, 2.33693) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4797 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8851 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 27/27 (100.0%) \cell -\pard\intbl\qc\fs18 73.39506 (69.55708, 77.23304) \cell -\pard\intbl\qc\fs18 -2.46914 (-5.76351, 0.82524) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4797 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8851 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2838 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4797 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8851 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit01apart4/tsfvit01apart4of4.rtf b/tests/testthat/_snaps/tsfvit01apart4/tsfvit01apart4of4.rtf deleted file mode 100644 index d7d7c8dc..00000000 --- a/tests/testthat/_snaps/tsfvit01apart4/tsfvit01apart4of4.rtf +++ /dev/null @@ -1,484 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7776 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT01apart4of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2852 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7776 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Blood Pressure \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?18 to <65 years \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 0.92262 (-13.44558, 15.29082) \cell -\pard\intbl\qc\fs18 0.64762 (-15.68080, 16.97604) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 -5.28571 (-21.58015, 11.00872) \cell -\pard\intbl\qc\fs18 9.51429 (-5.49428, 24.52286) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 -3.51667 (-26.65366, 19.62032) \cell -\pard\intbl\qc\fs18 -1.82222 (-25.84820, 22.20375) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 -0.48810 (-9.54353, 8.56734) \cell -\pard\intbl\qc\fs18 2.16190 (-6.49718, 10.82099) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 -0.79762 (-11.21097, 9.61573) \cell -\pard\intbl\qc\fs18 -4.44762 (-15.53590, 6.64066) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 0.40000 (-13.59849, 14.39849) \cell -\pard\intbl\qc\fs18 -2.26667 (-16.22660, 11.69327) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?65 to <75 years \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 3.14145 (-6.38129, 12.66419) \cell -\pard\intbl\qc\fs18 6.71620 (-1.50252, 14.93493) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 0.88268 (-7.79244, 9.55779) \cell -\pard\intbl\qc\fs18 7.97018 (0.02552, 15.91483) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 -5.90994 (-14.22874, 2.40886) \cell -\pard\intbl\qc\fs18 4.65302 (-1.53462, 10.84066) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 5.84320 (-0.20218, 11.88859) \cell -\pard\intbl\qc\fs18 7.45717 (1.50022, 13.41413) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 5.03618 (-2.07219, 12.14456) \cell -\pard\intbl\qc\fs18 7.50702 (0.68322, 14.33081) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 -0.81287 (-5.83409, 4.20835) \cell -\pard\intbl\qc\fs18 5.59454 (0.73739, 10.45169) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age: \u8805?75 years \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 -6.50180 (-13.68843, 0.68484) \cell -\pard\intbl\qc\fs18 -0.57334 (-6.46467, 5.31799) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 -5.50460 (-13.09021, 2.08101) \cell -\pard\intbl\qc\fs18 2.51053 (-5.14732, 10.16837) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 -6.92196 (-14.32368, 0.47977) \cell -\pard\intbl\qc\fs18 3.75661 (-2.99972, 10.51295) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Screening \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 -2.80963 (-7.93341, 2.31415) \cell -\pard\intbl\qc\fs18 1.23002 (-2.70204, 5.16208) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 -5.55862 (-10.21687, -0.90037) \cell -\pard\intbl\qc\fs18 0.81404 (-3.20707, 4.83514) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7776 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 -3.50705 (-8.23403, 1.21993) \cell -\pard\intbl\qc\fs18 1.12628 (-2.69639, 4.94895) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7776 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2852 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7776 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit01part1/tsfvit01part1of4.rtf b/tests/testthat/_snaps/tsfvit01part1/tsfvit01part1of4.rtf deleted file mode 100644 index 1f144dd1..00000000 --- a/tests/testthat/_snaps/tsfvit01part1/tsfvit01part1of4.rtf +++ /dev/null @@ -1,220 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2806 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8935 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT01part1of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2806 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8935 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8935 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Blood Pressure \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2806 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8935 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Screening \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 138.2390 (133.5179, 142.9601) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 131.7170 (127.5681, 135.8659) \cell -\pard\intbl\qc\fs18 -6.5220 (-10.7477, -2.2963) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 130.7421 (126.5700, 134.9143) \cell -\pard\intbl\qc\fs18 -7.4969 (-11.4782, -3.5155) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 129.9477 (125.8664, 134.0290) \cell -\pard\intbl\qc\fs18 -8.9869 (-13.2844, -4.6895) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Screening \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 79.3333 (76.6476, 82.0190) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 77.1069 (74.5509, 79.6630) \cell -\pard\intbl\qc\fs18 -2.2264 (-4.9097, 0.4569) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 76.0252 (73.5603, 78.4900) \cell -\pard\intbl\qc\fs18 -3.3082 (-6.1264, -0.4899) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2806 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8935 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 75.3137 (72.6005, 78.0269) \cell -\pard\intbl\qc\fs18 -4.2614 (-6.7224, -1.8005) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2806 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8935 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8935 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit01part2/tsfvit01part2of4.rtf b/tests/testthat/_snaps/tsfvit01part2/tsfvit01part2of4.rtf deleted file mode 100644 index 5fc70345..00000000 --- a/tests/testthat/_snaps/tsfvit01part2/tsfvit01part2of4.rtf +++ /dev/null @@ -1,220 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5020 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9127 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT01part2of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2814 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5020 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9127 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5020 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9127 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Blood Pressure \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5020 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9127 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Screening \cell -\pard\intbl\qc\fs18 73/73 (100.0%) \cell -\pard\intbl\qc\fs18 138.7352 (134.5082, 142.9621) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 71/71 (100.0%) \cell -\pard\intbl\qc\fs18 135.3192 (131.2528, 139.3857) \cell -\pard\intbl\qc\fs18 -3.0986 (-6.2424, 0.0452) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 137.6478 (132.7251, 142.5705) \cell -\pard\intbl\qc\fs18 -0.1321 (-4.2817, 4.0175) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 135.7872 (130.2234, 141.3510) \cell -\pard\intbl\qc\fs18 -0.6809 (-4.1263, 2.7646) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Screening \cell -\pard\intbl\qc\fs18 73/73 (100.0%) \cell -\pard\intbl\qc\fs18 76.6256 (74.4932, 78.7579) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 71/71 (100.0%) \cell -\pard\intbl\qc\fs18 76.7324 (74.3843, 79.0804) \cell -\pard\intbl\qc\fs18 0.2207 (-1.4974, 1.9388) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 53/53 (100.0%) \cell -\pard\intbl\qc\fs18 76.8553 (74.3209, 79.3898) \cell -\pard\intbl\qc\fs18 0.2138 (-1.9788, 2.4065) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5020 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9127 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 47/47 (100.0%) \cell -\pard\intbl\qc\fs18 75.1844 (72.5599, 77.8089) \cell -\pard\intbl\qc\fs18 -0.5177 (-2.3210, 1.2855) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5020 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9127 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5020 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9127 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit01part3/tsfvit01part3of4.rtf b/tests/testthat/_snaps/tsfvit01part3/tsfvit01part3of4.rtf deleted file mode 100644 index 01553dbc..00000000 --- a/tests/testthat/_snaps/tsfvit01part3/tsfvit01part3of4.rtf +++ /dev/null @@ -1,220 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2840 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5006 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9040 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT01part3of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2840 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5006 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9040 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5006 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9040 -\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Blood Pressure \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2840 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5006 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9040 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr n/N (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Mean Change From Baseline (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Screening \cell -\pard\intbl\qc\fs18 59/59 (100.0%) \cell -\pard\intbl\qc\fs18 135.7627 (131.0746, 140.4508) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 58/58 (100.0%) \cell -\pard\intbl\qc\fs18 131.3966 (126.7814, 136.0117) \cell -\pard\intbl\qc\fs18 -4.2241 (-7.5565, -0.8917) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 56/56 (100.0%) \cell -\pard\intbl\qc\fs18 131.3512 (126.5164, 136.1860) \cell -\pard\intbl\qc\fs18 -4.0476 (-7.6489, -0.4464) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 131.6340 (126.4963, 136.7717) \cell -\pard\intbl\qc\fs18 -2.5686 (-6.1802, 1.0430) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Screening \cell -\pard\intbl\qc\fs18 59/59 (100.0%) \cell -\pard\intbl\qc\fs18 76.2599 (73.5325, 78.9872) \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 58/58 (100.0%) \cell -\pard\intbl\qc\fs18 73.7816 (71.1451, 76.4181) \cell -\pard\intbl\qc\fs18 -2.4828 (-4.9920, 0.0264) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 56/56 (100.0%) \cell -\pard\intbl\qc\fs18 74.2976 (71.2455, 77.3498) \cell -\pard\intbl\qc\fs18 -1.7619 (-4.2062, 0.6823) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5006 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9040 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 51/51 (100.0%) \cell -\pard\intbl\qc\fs18 74.3399 (71.4934, 77.1864) \cell -\pard\intbl\qc\fs18 -2.1176 (-4.3514, 0.1161) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2840 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5006 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9040 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5006 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9040 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit01part4/tsfvit01part4of4.rtf b/tests/testthat/_snaps/tsfvit01part4/tsfvit01part4of4.rtf deleted file mode 100644 index 1e096ff2..00000000 --- a/tests/testthat/_snaps/tsfvit01part4/tsfvit01part4of4.rtf +++ /dev/null @@ -1,184 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2811 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8121 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT01part4of4:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2811 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8121 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Mean Change (95% CI) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Blood Pressure \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Screening \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 -2.2979 (-7.6221, 3.0264) \cell -\pard\intbl\qc\fs18 1.1255 (-3.4113, 5.6624) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 -3.4492 (-8.7568, 1.8584) \cell -\pard\intbl\qc\fs18 3.9155 (-1.5172, 9.3483) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 -6.4183 (-11.9651, -0.8715) \cell -\pard\intbl\qc\fs18 1.8878 (-3.0400, 6.8156) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Screening \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 0.2563 (-3.3763, 3.8889) \cell -\pard\intbl\qc\fs18 2.7034 (-0.3118, 5.7186) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell -\pard\intbl\qc\fs18 -1.5463 (-5.2349, 2.1424) \cell -\pard\intbl\qc\fs18 1.9757 (-1.2708, 5.2222) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8121 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 -2.1438 (-5.4270, 1.1394) \cell -\pard\intbl\qc\fs18 1.5999 (-1.2358, 4.4356) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2811 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8121 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8121 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit02/tsfvit02.rtf b/tests/testthat/_snaps/tsfvit02/tsfvit02.rtf old mode 100755 new mode 100644 index 7e72d657..59b10f09 --- a/tests/testthat/_snaps/tsfvit02/tsfvit02.rtf +++ b/tests/testthat/_snaps/tsfvit02/tsfvit02.rtf @@ -41,11 +41,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell \row } @@ -56,10 +56,10 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6045 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7652 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Systolic Blood Pressure (mmHg), n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Parameter, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row @@ -72,12 +72,188 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 N \cell -\pard\intbl\qc\fs18 49 \cell -\pard\intbl\qc\fs18 69 \cell -\pard\intbl\qc\fs18 55 \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Maximum systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 <90 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?90 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?120 \cell +\pard\intbl\qc\fs18 60 (90.9%) \cell +\pard\intbl\qc\fs18 49 (96.1%) \cell +\pard\intbl\qc\fs18 60 (96.8%) \cell +\pard\intbl\qc\fs18 -5.9 (-14.1, 2.3) \cell +\pard\intbl\qc\fs18 -0.7 (-7.6, 6.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?140 \cell +\pard\intbl\qc\fs18 37 (56.1%) \cell +\pard\intbl\qc\fs18 27 (52.9%) \cell +\pard\intbl\qc\fs18 37 (59.7%) \cell +\pard\intbl\qc\fs18 -3.6 (-20.7, 13.5) \cell +\pard\intbl\qc\fs18 -6.7 (-25.1, 11.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?160 \cell +\pard\intbl\qc\fs18 15 (22.7%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (22.6%) \cell +\pard\intbl\qc\fs18 0.1 (-14.4, 14.7) \cell +\pard\intbl\qc\fs18 -12.8 (-26.0, 0.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?180 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (3.2%) \cell +\pard\intbl\qc\fs18 -3.2 (-7.6, 1.2) \cell +\pard\intbl\qc\fs18 -1.3 (-7.1, 4.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Maximum diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 <60 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -88,12 +264,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 <90 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?60 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (7.3%) \cell -\pard\intbl\qc\fs18 -7.3 (-14.1, -0.4) \cell -\pard\intbl\qc\fs18 -7.3 (-14.1, -0.4) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -104,12 +280,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?90 to 119 \cell -\pard\intbl\qc\fs18 27 (55.1%) \cell -\pard\intbl\qc\fs18 23 (33.3%) \cell -\pard\intbl\qc\fs18 27 (49.1%) \cell -\pard\intbl\qc\fs18 6.0 (-13.2, 25.2) \cell -\pard\intbl\qc\fs18 -15.8 (-33.0, 1.5) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?80 \cell +\pard\intbl\qc\fs18 30 (45.5%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 35 (56.5%) \cell +\pard\intbl\qc\fs18 -11.0 (-28.2, 6.2) \cell +\pard\intbl\qc\fs18 18.1 (0.9, 35.2) \cell \row } @@ -120,12 +296,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?120 to 139 \cell -\pard\intbl\qc\fs18 17 (34.7%) \cell -\pard\intbl\qc\fs18 30 (43.5%) \cell -\pard\intbl\qc\fs18 18 (32.7%) \cell -\pard\intbl\qc\fs18 2.0 (-16.2, 20.2) \cell -\pard\intbl\qc\fs18 10.8 (-6.3, 27.8) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?90 \cell +\pard\intbl\qc\fs18 11 (16.7%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 12 (19.4%) \cell +\pard\intbl\qc\fs18 -2.7 (-16.0, 10.6) \cell +\pard\intbl\qc\fs18 4.2 (-11.1, 19.4) \cell \row } @@ -136,12 +312,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?140 to 159 \cell -\pard\intbl\qc\fs18 5 (10.2%) \cell -\pard\intbl\qc\fs18 12 (17.4%) \cell -\pard\intbl\qc\fs18 6 (10.9%) \cell -\pard\intbl\qc\fs18 -0.7 (-12.5, 11.1) \cell -\pard\intbl\qc\fs18 6.5 (-5.7, 18.6) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?110 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } @@ -152,12 +328,76 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?160 to 179 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?120 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hypotension (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4438 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10176 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Systolic blood pressure <90 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 5.8 (0.3, 11.3) \cell \row } @@ -168,7 +408,7 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6045 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7652 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10176 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?180 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Diastolic blood pressure <60 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell diff --git a/tests/testthat/_snaps/tsfvit03/tsfvit03.rtf b/tests/testthat/_snaps/tsfvit03/tsfvit03.rtf old mode 100755 new mode 100644 index 77dcb6c4..c253743d --- a/tests/testthat/_snaps/tsfvit03/tsfvit03.rtf +++ b/tests/testthat/_snaps/tsfvit03/tsfvit03.rtf @@ -1,16 +1,12 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2840 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4497 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6154 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7810 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10256 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT03:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2757 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4901 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7045 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT03:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -19,63 +15,71 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2840 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4497 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6154 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7810 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10256 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2757 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4901 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7045 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Study Visit \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4497 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7810 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10256 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Parameter \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4497 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6154 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7810 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10256 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Diastolic Blood Pressure (mmHg), n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li270\fi0 Criteria, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 On-treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4497 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6154 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7810 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10256 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 70 \cell -\pard\intbl\qc\fs18 58 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -83,110 +87,4258 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4497 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7810 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 <60 \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 8 (11.4%) \cell -\pard\intbl\qc\fs18 9 (15.5%) \cell -\pard\intbl\qc\fs18 -4.2 (-16.8, 8.4) \cell -\pard\intbl\qc\fs18 -4.1 (-16.0, 7.8) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4497 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7810 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?60 to 89 \cell -\pard\intbl\qc\fs18 47 (88.7%) \cell -\pard\intbl\qc\fs18 61 (87.1%) \cell -\pard\intbl\qc\fs18 48 (82.8%) \cell -\pard\intbl\qc\fs18 5.9 (-7.0, 18.9) \cell -\pard\intbl\qc\fs18 4.4 (-8.1, 16.9) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4497 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7810 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?90 to 109 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 -1.7 (-5.1, 1.6) \cell -\pard\intbl\qc\fs18 -0.3 (-4.6, 4.1) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4497 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6154 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7810 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10256 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?110 to 119 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2840 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4497 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6154 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7810 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10256 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?120 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell -\pard\intbl\qc\fs18 0.0 (0.0, 0.0) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2840 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4497 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6154 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7810 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10256 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4497 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6154 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7810 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10256 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 06 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 07 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 08 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 1 (4.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 09 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 10 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 11 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 62 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 13 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 52 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 17 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 48 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 23 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 25 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 29 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 47 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 End Of Treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 41 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 <50 beats/min and with >20 beats/min decrease from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2757 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4901 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7045 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 >120 beats/min and with >30 beats/min increase from baseline \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2757 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4901 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7045 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2757 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4901 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7045 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfvit04/tsfvit04.rtf b/tests/testthat/_snaps/tsfvit04/tsfvit04.rtf old mode 100755 new mode 100644 index 91736bb7..4b1e9ec8 --- a/tests/testthat/_snaps/tsfvit04/tsfvit04.rtf +++ b/tests/testthat/_snaps/tsfvit04/tsfvit04.rtf @@ -1,16 +1,12 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4341 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5869 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7396 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10049 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT04:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT04:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -19,63 +15,47 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2814 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4341 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5869 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7396 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10049 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2828 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4948 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7069 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Blood Pressure (mmHg), n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Orthostatic Hypotension, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 On-treatment \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -83,62 +63,1510 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure<90 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (6.9%) \cell -\pard\intbl\qc\fs18 -6.9 (-13.4, -0.4) \cell -\pard\intbl\qc\fs18 -6.9 (-13.4, -0.4) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 35 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4341 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5869 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7396 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10049 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure<60 \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 8 (11.3%) \cell -\pard\intbl\qc\fs18 9 (15.5%) \cell -\pard\intbl\qc\fs18 -4.2 (-16.8, 8.4) \cell -\pard\intbl\qc\fs18 -4.2 (-16.1, 7.6) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 33 (78.6%) \cell +\pard\intbl\qc\fs18 28 (96.6%) \cell +\pard\intbl\qc\fs18 33 (94.3%) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4341 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5869 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7396 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10049 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 21 (50.0%) \cell +\pard\intbl\qc\fs18 19 (65.5%) \cell +\pard\intbl\qc\fs18 26 (74.3%) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2814 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4341 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5869 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7396 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10049 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 33 (78.6%) \cell +\pard\intbl\qc\fs18 27 (93.1%) \cell +\pard\intbl\qc\fs18 29 (82.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 21 (50.0%) \cell +\pard\intbl\qc\fs18 19 (65.5%) \cell +\pard\intbl\qc\fs18 11 (31.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 6 (14.3%) \cell +\pard\intbl\qc\fs18 9 (31.0%) \cell +\pard\intbl\qc\fs18 7 (20.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 18 (42.9%) \cell +\pard\intbl\qc\fs18 12 (41.4%) \cell +\pard\intbl\qc\fs18 5 (14.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 13 (43.3%) \cell +\pard\intbl\qc\fs18 15 (51.7%) \cell +\pard\intbl\qc\fs18 16 (45.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 5 (16.7%) \cell +\pard\intbl\qc\fs18 4 (13.8%) \cell +\pard\intbl\qc\fs18 8 (22.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 9 (30.0%) \cell +\pard\intbl\qc\fs18 14 (48.3%) \cell +\pard\intbl\qc\fs18 9 (25.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 12 (42.9%) \cell +\pard\intbl\qc\fs18 10 (37.0%) \cell +\pard\intbl\qc\fs18 21 (65.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 7 (25.0%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 13 (40.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 9 (32.1%) \cell +\pard\intbl\qc\fs18 9 (33.3%) \cell +\pard\intbl\qc\fs18 12 (37.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 05 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 30 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 14 (53.8%) \cell +\pard\intbl\qc\fs18 10 (43.5%) \cell +\pard\intbl\qc\fs18 11 (36.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 4 (15.4%) \cell +\pard\intbl\qc\fs18 3 (13.0%) \cell +\pard\intbl\qc\fs18 4 (13.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 10 (38.5%) \cell +\pard\intbl\qc\fs18 8 (34.8%) \cell +\pard\intbl\qc\fs18 7 (23.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 06 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 7 (31.8%) \cell +\pard\intbl\qc\fs18 11 (52.4%) \cell +\pard\intbl\qc\fs18 11 (39.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 2 (9.1%) \cell +\pard\intbl\qc\fs18 4 (19.0%) \cell +\pard\intbl\qc\fs18 6 (21.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 5 (22.7%) \cell +\pard\intbl\qc\fs18 7 (33.3%) \cell +\pard\intbl\qc\fs18 8 (28.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 07 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 9 (47.4%) \cell +\pard\intbl\qc\fs18 8 (44.4%) \cell +\pard\intbl\qc\fs18 12 (42.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 5 (26.3%) \cell +\pard\intbl\qc\fs18 3 (16.7%) \cell +\pard\intbl\qc\fs18 6 (21.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 7 (36.8%) \cell +\pard\intbl\qc\fs18 7 (38.9%) \cell +\pard\intbl\qc\fs18 9 (32.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 08 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 6 (42.9%) \cell +\pard\intbl\qc\fs18 6 (40.0%) \cell +\pard\intbl\qc\fs18 8 (29.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 5 (35.7%) \cell +\pard\intbl\qc\fs18 6 (40.0%) \cell +\pard\intbl\qc\fs18 7 (25.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 09 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 23 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 6 (46.2%) \cell +\pard\intbl\qc\fs18 8 (57.1%) \cell +\pard\intbl\qc\fs18 13 (56.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 3 (21.4%) \cell +\pard\intbl\qc\fs18 4 (17.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 5 (38.5%) \cell +\pard\intbl\qc\fs18 5 (35.7%) \cell +\pard\intbl\qc\fs18 10 (43.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 10 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 22 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 4 (30.8%) \cell +\pard\intbl\qc\fs18 7 (50.0%) \cell +\pard\intbl\qc\fs18 13 (59.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 2 (15.4%) \cell +\pard\intbl\qc\fs18 3 (21.4%) \cell +\pard\intbl\qc\fs18 5 (22.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 2 (15.4%) \cell +\pard\intbl\qc\fs18 4 (28.6%) \cell +\pard\intbl\qc\fs18 10 (45.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 11 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 21 (50.0%) \cell +\pard\intbl\qc\fs18 19 (65.5%) \cell +\pard\intbl\qc\fs18 11 (31.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 6 (14.3%) \cell +\pard\intbl\qc\fs18 9 (31.0%) \cell +\pard\intbl\qc\fs18 7 (20.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 18 (42.9%) \cell +\pard\intbl\qc\fs18 12 (41.4%) \cell +\pard\intbl\qc\fs18 5 (14.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 12 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 35 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 13 (43.3%) \cell +\pard\intbl\qc\fs18 15 (51.7%) \cell +\pard\intbl\qc\fs18 16 (45.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 5 (16.7%) \cell +\pard\intbl\qc\fs18 4 (13.8%) \cell +\pard\intbl\qc\fs18 8 (22.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 9 (30.0%) \cell +\pard\intbl\qc\fs18 14 (48.3%) \cell +\pard\intbl\qc\fs18 9 (25.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 13 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 28 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 32 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 12 (42.9%) \cell +\pard\intbl\qc\fs18 10 (37.0%) \cell +\pard\intbl\qc\fs18 21 (65.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 7 (25.0%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 13 (40.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 9 (32.1%) \cell +\pard\intbl\qc\fs18 9 (33.3%) \cell +\pard\intbl\qc\fs18 12 (37.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 26 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 30 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 14 (53.8%) \cell +\pard\intbl\qc\fs18 10 (43.5%) \cell +\pard\intbl\qc\fs18 11 (36.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 4 (15.4%) \cell +\pard\intbl\qc\fs18 3 (13.0%) \cell +\pard\intbl\qc\fs18 4 (13.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 10 (38.5%) \cell +\pard\intbl\qc\fs18 8 (34.8%) \cell +\pard\intbl\qc\fs18 7 (23.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 17 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 7 (31.8%) \cell +\pard\intbl\qc\fs18 11 (52.4%) \cell +\pard\intbl\qc\fs18 11 (39.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 2 (9.1%) \cell +\pard\intbl\qc\fs18 4 (19.0%) \cell +\pard\intbl\qc\fs18 6 (21.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 5 (22.7%) \cell +\pard\intbl\qc\fs18 7 (33.3%) \cell +\pard\intbl\qc\fs18 8 (28.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 19 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 18 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 9 (47.4%) \cell +\pard\intbl\qc\fs18 8 (44.4%) \cell +\pard\intbl\qc\fs18 12 (42.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 5 (26.3%) \cell +\pard\intbl\qc\fs18 3 (16.7%) \cell +\pard\intbl\qc\fs18 6 (21.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 7 (36.8%) \cell +\pard\intbl\qc\fs18 7 (38.9%) \cell +\pard\intbl\qc\fs18 9 (32.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 21 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 6 (42.9%) \cell +\pard\intbl\qc\fs18 6 (40.0%) \cell +\pard\intbl\qc\fs18 8 (29.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 5 (35.7%) \cell +\pard\intbl\qc\fs18 6 (40.0%) \cell +\pard\intbl\qc\fs18 7 (25.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 23 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 23 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 6 (46.2%) \cell +\pard\intbl\qc\fs18 8 (57.1%) \cell +\pard\intbl\qc\fs18 13 (56.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 3 (21.4%) \cell +\pard\intbl\qc\fs18 4 (17.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 5 (38.5%) \cell +\pard\intbl\qc\fs18 5 (35.7%) \cell +\pard\intbl\qc\fs18 10 (43.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 25 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 22 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 4 (30.8%) \cell +\pard\intbl\qc\fs18 7 (50.0%) \cell +\pard\intbl\qc\fs18 13 (59.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 2 (15.4%) \cell +\pard\intbl\qc\fs18 3 (21.4%) \cell +\pard\intbl\qc\fs18 5 (22.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 2 (15.4%) \cell +\pard\intbl\qc\fs18 4 (28.6%) \cell +\pard\intbl\qc\fs18 10 (45.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 29 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 27 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 6 (42.9%) \cell +\pard\intbl\qc\fs18 6 (40.0%) \cell +\pard\intbl\qc\fs18 8 (29.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 1 (7.1%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 5 (35.7%) \cell +\pard\intbl\qc\fs18 6 (40.0%) \cell +\pard\intbl\qc\fs18 7 (25.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 End Of Treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 14 \cell +\pard\intbl\qc\fs18 23 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total number of subjects with orthostatic hypotension \cell +\pard\intbl\qc\fs18 6 (46.2%) \cell +\pard\intbl\qc\fs18 8 (57.1%) \cell +\pard\intbl\qc\fs18 13 (56.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 SBP (STD-SUP)<-20 \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 3 (21.4%) \cell +\pard\intbl\qc\fs18 4 (17.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 DBP (STD-SUP)<-10 \cell +\pard\intbl\qc\fs18 5 (38.5%) \cell +\pard\intbl\qc\fs18 5 (35.7%) \cell +\pard\intbl\qc\fs18 10 (43.5%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsfvit05/tsfvit05.rtf b/tests/testthat/_snaps/tsfvit05/tsfvit05.rtf deleted file mode 100755 index 2194c977..00000000 --- a/tests/testthat/_snaps/tsfvit05/tsfvit05.rtf +++ /dev/null @@ -1,640 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2804 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3894 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6542 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT05:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2804 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3894 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6542 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Study Visit \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Parameter \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li270\fi0 Criteria, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 On-treatment \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 bpm and with >20 bpm decrease from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >120 bpm and with >30 bpm increase from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 02 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 bpm and with >20 bpm decrease from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >120 bpm and with >30 bpm increase from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 71 \cell -\pard\intbl\qc\fs18 58 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 04 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulse rate (beats/min) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 47 \cell -\pard\intbl\qc\fs18 51 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 bpm and with >20 bpm decrease from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >120 bpm and with >30 bpm increase from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 47 \cell -\pard\intbl\qc\fs18 51 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <90 mmHg and with >30 mmHg decrease from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >180 mmHg and with >40 mmHg increase from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diastolic blood pressure (mmHg) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell -\pard\intbl\qc\fs18 51 \cell -\pard\intbl\qc\fs18 47 \cell -\pard\intbl\qc\fs18 51 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <50 mmHg and with >20 mmHg decrease from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2804 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3894 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6542 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 >105 mmHg and with >30 mmHg increase from baseline \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2804 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3894 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6542 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2804 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3894 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6542 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfvit06/tsfvit06.rtf b/tests/testthat/_snaps/tsfvit06/tsfvit06.rtf deleted file mode 100755 index 09cf01d6..00000000 --- a/tests/testthat/_snaps/tsfvit06/tsfvit06.rtf +++ /dev/null @@ -1,124 +0,0 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFVIT06:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2828 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7069 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Orthostatic hypotension, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 N \cell -\pard\intbl\qc\fs18 28 \cell -\pard\intbl\qc\fs18 39 \cell -\pard\intbl\qc\fs18 37 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of subjects with orthostatic hypotension \cell -\pard\intbl\qc\fs18 25 (89.3%) \cell -\pard\intbl\qc\fs18 33 (84.6%) \cell -\pard\intbl\qc\fs18 34 (91.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 DBP (STD-SUP) <-10 \cell -\pard\intbl\qc\fs18 25 (89.3%) \cell -\pard\intbl\qc\fs18 28 (71.8%) \cell -\pard\intbl\qc\fs18 32 (86.5%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 SBP (STD-SUP) <-20 \cell -\pard\intbl\qc\fs18 19 (67.9%) \cell -\pard\intbl\qc\fs18 20 (51.3%) \cell -\pard\intbl\qc\fs18 26 (70.3%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsicm01/tsicm01.rtf b/tests/testthat/_snaps/tsicm01/tsicm01.rtf old mode 100755 new mode 100644 index 9e07b109..d76fd56a --- a/tests/testthat/_snaps/tsicm01/tsicm01.rtf +++ b/tests/testthat/_snaps/tsicm01/tsicm01.rtf @@ -20,11 +20,43 @@ { \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2854 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8652 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10584 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4786 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6719 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8652 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10584 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 ATC Level 2 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4786 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 ATC Level 3 \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -40,9 +72,9 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li540\fi0 ATC Level 4 \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell @@ -56,12 +88,12 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Standardized Medication Name \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=185 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li810\fi0 Standardized Medication Name, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=182 \cell \row } @@ -73,11 +105,11 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 concomitant medication \cell -\pard\intbl\qc\fs18 38 (71.7%) \cell -\pard\intbl\qc\fs18 43 (58.9%) \cell -\pard\intbl\qc\fs18 81 (64.3%) \cell -\pard\intbl\qc\fs18 35 (59.3%) \cell -\pard\intbl\qc\fs18 116 (62.7%) \cell +\pard\intbl\qc\fs18 42 (62.7%) \cell +\pard\intbl\qc\fs18 39 (76.5%) \cell +\pard\intbl\qc\fs18 81 (68.6%) \cell +\pard\intbl\qc\fs18 37 (57.8%) \cell +\pard\intbl\qc\fs18 118 (64.8%) \cell \row } @@ -105,11 +137,91 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Uncoded \cell -\pard\intbl\qc\fs18 34 (64.2%) \cell -\pard\intbl\qc\fs18 35 (47.9%) \cell -\pard\intbl\qc\fs18 69 (54.8%) \cell -\pard\intbl\qc\fs18 34 (57.6%) \cell -\pard\intbl\qc\fs18 103 (55.7%) \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrocortisone, topical \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 14 (27.5%) \cell +\pard\intbl\qc\fs18 23 (19.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 27 (14.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cortisone \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 17 (9.3%) \cell \row } @@ -120,12 +232,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocortisone, topical \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 23 (18.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 27 (14.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: benadryl \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -136,12 +248,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cortisone \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 16 (8.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: claritin \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 10 (5.5%) \cell \row } @@ -152,12 +264,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: benadryl \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 14 (7.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ativan \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 8 (4.4%) \cell \row } @@ -168,12 +280,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ativan \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lorazepam \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } @@ -184,11 +296,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: claritin \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: advil \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 5 (2.7%) \cell \row } @@ -200,10 +312,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lorazepam \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: calamine lotion \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 5 (2.7%) \cell \row @@ -216,11 +328,27 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: calamine lotion \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: neosporin /usa/ \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sudafed \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } @@ -232,10 +360,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lidex \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: biaxin \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row @@ -248,11 +376,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: motrin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin e \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } @@ -264,11 +392,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: robitussin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: amoxicillin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } @@ -280,12 +408,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: advil \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lidex \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } @@ -296,11 +424,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: robitussin-dm \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: robitussin-dm \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -312,12 +440,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: allegra \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: motrin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -328,12 +456,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: bactrim \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -344,12 +472,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: erythromycin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: erythromycin \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -360,12 +488,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ibuprofen \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: robitussin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -376,12 +504,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: multivitamin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: kenalog \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -392,11 +520,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: neosporin /usa/ \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: mylanta \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -408,11 +536,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prilosec \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cipro \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -424,11 +552,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sudafed \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: imodium a-d \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -440,11 +568,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sulfamethoxazole \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tums \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -456,11 +584,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ibuprofen \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -472,11 +600,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin c \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: allegra \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -488,11 +616,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin e \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: augmentin \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -504,12 +632,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: acetaminophen \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diphenhydramine hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -520,12 +648,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: albuterol \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: phenergan \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -536,12 +664,28 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: aloe vera \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: westcort \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: melatonin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -552,12 +696,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: amoxicillin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin b12 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -568,12 +712,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: antihistamines for systemic use \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: acetaminophen \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -584,12 +728,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: armour thyroid \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hismanal \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -600,11 +744,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: augmentin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sulfamethoxazole \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -616,11 +760,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: beconase \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: antihistamines for systemic use \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -632,9 +776,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: biaxin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: rocephin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -648,11 +792,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: bromatane dx \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: demerol \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -664,11 +808,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cefaclor \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol w/codeine no. 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -680,9 +824,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ceftin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lomotil \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -696,9 +840,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cephalexin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diabeta \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -712,11 +856,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cephalosporin c \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin c \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -728,9 +872,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: chloral hydrate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: neo-synephrine \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -744,9 +888,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cimetidine \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pseudoephedrine hydrochloride \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -760,11 +904,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cipro \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cefaclor \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -776,11 +920,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: coricidin d \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: kaopectate \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -792,11 +936,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: corticosteroids, dermatological preparations \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cephalosporin c \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -808,11 +952,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: dalmane \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: persantine \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -824,9 +968,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: demerol \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: glyburide \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -840,9 +984,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diabeta \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: polysporin \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -856,11 +1000,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diltiazem hydrochloride \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sinemet \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -872,11 +1016,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diphenhydramine hydrochloride \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: preparation h \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -888,11 +1032,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diprolene cream \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: metamucil \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -904,11 +1048,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: donepezil hydrochloride \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol sinus \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -920,11 +1064,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: doxycycline \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: topicort \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -936,11 +1080,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: droperidol \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: triamcinolone \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -952,9 +1096,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: estrace \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pepto-bismol \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -968,9 +1112,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: fluocinolone acetonide \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pertussin syrup \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -984,8 +1128,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: fluoroplex \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vicks formula 44d \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1000,9 +1144,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: furosemide \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: beconase \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1016,9 +1160,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: general anesthesia \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pepcid ac \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1032,9 +1176,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: glyburide \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: robitussin a-c \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1048,11 +1192,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: guiatuss \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: guaifenex \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1064,11 +1208,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: halotussin-dm \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: keflex \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1080,11 +1224,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: herbal preparation \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: bactrim \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1096,9 +1240,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocodone \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: premarin vaginal cream \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1112,8 +1256,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocodone w/apap \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: armour thyroid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1128,11 +1272,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocortisone valerate \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: maxzide \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1144,11 +1288,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: icy hot \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: polysporin ointment \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1160,9 +1304,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: influenza virus vaccine \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: toradol \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1176,11 +1320,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: keflex \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: phenazopyridine \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1192,11 +1336,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: kenalog \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: metronidazole \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1208,11 +1352,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lac-hydrin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lansoprazole \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1224,11 +1368,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lansoprazole \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: droperidol \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1240,11 +1384,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lipitor \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prilosec \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1256,11 +1400,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lomotil \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: propulsid \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1272,11 +1416,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: magnesium oxide \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prempro \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1288,11 +1432,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: mavik \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: doxycycline \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1304,11 +1448,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: maxzide \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: terazol \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1320,11 +1464,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: melatonin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: herbal preparation \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1336,11 +1480,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: metamucil \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: coricidin d \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1352,11 +1496,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: metronidazole \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diprolene cream \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1368,11 +1512,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: mevacor \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: bromatane dx \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1384,11 +1528,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: monopril \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zithromax \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1400,9 +1544,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: mylanta \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol extra strength \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1416,9 +1560,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: naproxen \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: multivitamin \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1432,11 +1576,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: neo-synephrine \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: albuterol \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1448,11 +1592,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: olanzapine \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: monopril \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1464,9 +1608,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pepcid \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: chlorpheniramine maleate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1480,9 +1624,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: persantine \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: chloral hydrate \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1496,9 +1640,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pertussin syrup \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zocor \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1512,11 +1656,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: phenazopyridine \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: halotussin-dm \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1528,8 +1672,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: phenergan \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ceftin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1544,11 +1688,27 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pilocarpine hydrochloride \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: estrace \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: furosemide \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1560,11 +1720,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pneumovax \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrocortisone valerate \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1576,9 +1736,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: polysporin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: influenza virus vaccine \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1592,8 +1752,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: polysporin ointment \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lanacane \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1608,11 +1768,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: potassium chloride \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: mavik \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1624,11 +1784,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prednisone \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: corticosteroids, dermatological preparations \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1640,9 +1800,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: premarin vaginal cream \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: aloes \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1656,11 +1816,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prempro \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: dhea \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1672,9 +1832,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: preparation h \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: medrol dosepak \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1688,9 +1848,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: promethazine hcl w/codeine \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prednisone \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1704,11 +1864,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: propulsid \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zoloft \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1720,9 +1880,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pseudoephedrine hydrochloride \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: benzonatate \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1736,9 +1896,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: rocephin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diltiazem hydrochloride \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1752,11 +1912,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sinemet \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: donepezil hydrochloride \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1768,11 +1928,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sulfacetamide \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: magnesium oxide \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1784,11 +1944,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: terazol \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: olanzapine \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1800,9 +1960,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: topicort \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: potassium chloride \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1816,9 +1976,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: toradol \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zantac \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1832,12 +1992,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: triamcinolone \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -1848,12 +2008,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: trimox \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -1864,12 +2024,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tums \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -1880,12 +2040,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol extra strength \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -1896,12 +2056,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol sinus \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -1912,12 +2072,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol w/codeine no. 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Hydrocortisone \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -1928,12 +2088,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vicks formula 44d \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -1944,12 +2104,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin b12 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } @@ -1960,12 +2120,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: westcort \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } @@ -1976,12 +2136,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zantac \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } @@ -1992,12 +2152,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zithromax \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } @@ -2008,12 +2168,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zocor \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Donepezil hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -2024,12 +2184,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Acetylsalicylic acid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -2040,12 +2200,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Paroxetine hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2056,12 +2216,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hydrocortisone \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Haloperidol \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2088,12 +2248,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -2104,11 +2264,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Donepezil hydrochloride \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -2120,12 +2280,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acetylsalicylic acid \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -2136,12 +2296,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Haloperidol \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -2152,11 +2312,27 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Paroxetine hydrochloride \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Loperamide hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Algeldrate \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2185,11 +2361,43 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiovascular system \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -2200,10 +2408,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Doxazosin mesilate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -2216,9 +2424,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Digoxin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Doxazosin mesilate \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2232,9 +2440,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Losartan potassium \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Losartan potassium \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2264,12 +2472,28 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alimentary tract and metabolism \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory system \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Respiratory system \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2280,9 +2504,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cimetidine \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Respiratory system \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2296,11 +2520,27 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Loperamide hydrochloride \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Respiratory system \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Budesonide \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2329,8 +2569,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Dermatologicals \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2344,9 +2584,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Clobetasol propionate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dermatologicals \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2360,12 +2600,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dermatologicals \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2376,11 +2616,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory system \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Dermatologicals \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2392,11 +2632,11 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Guaifenesin \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Clobetasol propionate \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } diff --git a/tests/testthat/_snaps/tsicm02/tsicm02.rtf b/tests/testthat/_snaps/tsicm02/tsicm02.rtf old mode 100755 new mode 100644 index 23edae89..3c3f6e69 --- a/tests/testthat/_snaps/tsicm02/tsicm02.rtf +++ b/tests/testthat/_snaps/tsicm02/tsicm02.rtf @@ -20,11 +20,43 @@ { \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2854 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8652 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10584 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4786 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6719 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8652 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10584 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 ATC Level 2 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4786 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 ATC Level 3 \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -40,9 +72,9 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li540\fi0 ATC Level 4 \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell @@ -56,12 +88,12 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Base Preferred Term \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=185 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li810\fi0 Base Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=182 \cell \row } @@ -73,11 +105,11 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 concomitant medication \cell -\pard\intbl\qc\fs18 38 (71.7%) \cell -\pard\intbl\qc\fs18 43 (58.9%) \cell -\pard\intbl\qc\fs18 81 (64.3%) \cell -\pard\intbl\qc\fs18 35 (59.3%) \cell -\pard\intbl\qc\fs18 116 (62.7%) \cell +\pard\intbl\qc\fs18 42 (62.7%) \cell +\pard\intbl\qc\fs18 39 (76.5%) \cell +\pard\intbl\qc\fs18 81 (68.6%) \cell +\pard\intbl\qc\fs18 37 (57.8%) \cell +\pard\intbl\qc\fs18 118 (64.8%) \cell \row } @@ -105,11 +137,91 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Uncoded \cell -\pard\intbl\qc\fs18 34 (64.2%) \cell -\pard\intbl\qc\fs18 35 (47.9%) \cell -\pard\intbl\qc\fs18 69 (54.8%) \cell -\pard\intbl\qc\fs18 34 (57.6%) \cell -\pard\intbl\qc\fs18 103 (55.7%) \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrocortisone, topical \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 14 (27.5%) \cell +\pard\intbl\qc\fs18 23 (19.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 27 (14.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cortisone \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 17 (9.3%) \cell \row } @@ -120,12 +232,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocortisone, topical \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 23 (18.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 27 (14.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: benadryl \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -136,12 +248,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cortisone \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 16 (8.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: claritin \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 10 (5.5%) \cell \row } @@ -152,12 +264,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: benadryl \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 14 (7.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ativan \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 8 (4.4%) \cell \row } @@ -168,12 +280,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ativan \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lorazepam \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } @@ -184,11 +296,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: claritin \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: advil \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 5 (2.7%) \cell \row } @@ -200,10 +312,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lorazepam \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: calamine lotion \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 5 (2.7%) \cell \row @@ -216,11 +328,27 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: calamine lotion \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: neosporin /usa/ \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sudafed \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } @@ -232,10 +360,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lidex \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: biaxin \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row @@ -248,11 +376,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: motrin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin e \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } @@ -264,11 +392,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: robitussin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: amoxicillin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } @@ -280,12 +408,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: advil \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lidex \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } @@ -296,11 +424,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: robitussin-dm \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: robitussin-dm \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -312,12 +440,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: allegra \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: motrin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -328,12 +456,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: bactrim \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -344,12 +472,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: erythromycin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: erythromycin \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -360,12 +488,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ibuprofen \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: robitussin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -376,12 +504,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: multivitamin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: kenalog \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -392,11 +520,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: neosporin /usa/ \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: mylanta \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -408,11 +536,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prilosec \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cipro \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -424,11 +552,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sudafed \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: imodium a-d \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -440,11 +568,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sulfamethoxazole \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tums \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -456,11 +584,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ibuprofen \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -472,11 +600,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin c \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: allegra \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -488,11 +616,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin e \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: augmentin \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -504,12 +632,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: acetaminophen \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diphenhydramine hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -520,12 +648,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: albuterol \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: phenergan \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -536,12 +664,28 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: aloe vera \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: westcort \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: melatonin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -552,12 +696,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: amoxicillin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin b12 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -568,12 +712,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: antihistamines for systemic use \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: acetaminophen \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -584,12 +728,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: armour thyroid \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hismanal \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -600,11 +744,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: augmentin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sulfamethoxazole \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -616,11 +760,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: beconase \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: antihistamines for systemic use \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -632,9 +776,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: biaxin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: rocephin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -648,11 +792,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: bromatane dx \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: demerol \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -664,11 +808,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cefaclor \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol w/codeine no. 3 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -680,9 +824,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ceftin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lomotil \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -696,9 +840,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cephalexin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diabeta \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -712,11 +856,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cephalosporin c \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin c \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -728,9 +872,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: chloral hydrate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: neo-synephrine \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -744,9 +888,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cimetidine \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pseudoephedrine hydrochloride \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -760,11 +904,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cipro \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cefaclor \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -776,11 +920,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: coricidin d \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: kaopectate \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -792,11 +936,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: corticosteroids, dermatological preparations \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cephalosporin c \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -808,11 +952,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: dalmane \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: persantine \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -824,9 +968,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: demerol \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: glyburide \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -840,9 +984,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diabeta \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: polysporin \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -856,11 +1000,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diltiazem hydrochloride \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sinemet \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -872,11 +1016,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diphenhydramine hydrochloride \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: preparation h \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -888,11 +1032,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diprolene cream \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: metamucil \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -904,11 +1048,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: donepezil hydrochloride \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol sinus \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -920,11 +1064,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: doxycycline \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: topicort \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -936,11 +1080,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: droperidol \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: triamcinolone \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -952,9 +1096,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: estrace \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pepto-bismol \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -968,9 +1112,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: fluocinolone acetonide \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pertussin syrup \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -984,8 +1128,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: fluoroplex \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vicks formula 44d \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1000,9 +1144,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: furosemide \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: beconase \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1016,9 +1160,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: general anesthesia \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pepcid ac \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1032,9 +1176,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: glyburide \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: robitussin a-c \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1048,11 +1192,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: guiatuss \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: guaifenex \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1064,11 +1208,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: halotussin-dm \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: keflex \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1080,11 +1224,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: herbal preparation \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: bactrim \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1096,9 +1240,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocodone \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: premarin vaginal cream \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1112,8 +1256,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocodone w/apap \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: armour thyroid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1128,11 +1272,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocortisone valerate \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: maxzide \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1144,11 +1288,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: icy hot \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: polysporin ointment \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1160,9 +1304,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: influenza virus vaccine \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: toradol \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1176,11 +1320,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: keflex \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: phenazopyridine \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1192,11 +1336,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: kenalog \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: metronidazole \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1208,11 +1352,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lac-hydrin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lansoprazole \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1224,11 +1368,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lansoprazole \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: droperidol \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1240,11 +1384,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lipitor \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prilosec \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1256,11 +1400,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lomotil \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: propulsid \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1272,11 +1416,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: magnesium oxide \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prempro \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1288,11 +1432,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: mavik \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: doxycycline \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1304,11 +1448,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: maxzide \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: terazol \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1320,11 +1464,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: melatonin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: herbal preparation \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1336,11 +1480,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: metamucil \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: coricidin d \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1352,11 +1496,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: metronidazole \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diprolene cream \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1368,11 +1512,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: mevacor \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: bromatane dx \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1384,11 +1528,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: monopril \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zithromax \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1400,9 +1544,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: mylanta \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol extra strength \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1416,9 +1560,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: naproxen \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: multivitamin \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1432,11 +1576,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: neo-synephrine \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: albuterol \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1448,11 +1592,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: olanzapine \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: monopril \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1464,9 +1608,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pepcid \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: chlorpheniramine maleate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1480,9 +1624,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: persantine \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: chloral hydrate \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1496,9 +1640,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pertussin syrup \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zocor \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1512,11 +1656,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: phenazopyridine \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: halotussin-dm \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1528,8 +1672,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: phenergan \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ceftin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1544,11 +1688,27 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pilocarpine hydrochloride \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: estrace \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: furosemide \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1560,11 +1720,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pneumovax \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrocortisone valerate \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1576,9 +1736,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: polysporin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: influenza virus vaccine \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1592,8 +1752,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: polysporin ointment \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lanacane \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1608,11 +1768,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: potassium chloride \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: mavik \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1624,11 +1784,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prednisone \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: corticosteroids, dermatological preparations \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1640,9 +1800,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: premarin vaginal cream \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: aloes \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1656,11 +1816,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prempro \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: dhea \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1672,9 +1832,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: preparation h \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: medrol dosepak \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1688,9 +1848,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: promethazine hcl w/codeine \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prednisone \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1704,11 +1864,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: propulsid \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zoloft \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1720,9 +1880,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pseudoephedrine hydrochloride \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: benzonatate \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1736,9 +1896,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: rocephin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diltiazem hydrochloride \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1752,11 +1912,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sinemet \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: donepezil hydrochloride \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1768,11 +1928,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sulfacetamide \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: magnesium oxide \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1784,11 +1944,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: terazol \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: olanzapine \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -1800,9 +1960,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: topicort \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: potassium chloride \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1816,9 +1976,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: toradol \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zantac \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1832,12 +1992,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: triamcinolone \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -1848,12 +2008,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: trimox \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -1864,12 +2024,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tums \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -1880,12 +2040,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol extra strength \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -1896,12 +2056,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol sinus \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -1912,12 +2072,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol w/codeine no. 3 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Hydrocortisone \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -1928,12 +2088,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vicks formula 44d \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -1944,12 +2104,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin b12 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } @@ -1960,12 +2120,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: westcort \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } @@ -1976,12 +2136,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zantac \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } @@ -1992,12 +2152,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zithromax \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } @@ -2008,12 +2168,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zocor \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Donepezil hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -2024,12 +2184,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Acetylsalicylic acid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -2040,12 +2200,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Paroxetine hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2056,12 +2216,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hydrocortisone \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Haloperidol \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2088,12 +2248,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -2104,11 +2264,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Donepezil hydrochloride \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -2120,12 +2280,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acetylsalicylic acid \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -2136,12 +2296,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Haloperidol \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } @@ -2152,11 +2312,27 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Paroxetine hydrochloride \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Loperamide hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Algeldrate \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2185,11 +2361,43 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiovascular system \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } @@ -2200,10 +2408,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Doxazosin mesilate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -2216,9 +2424,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Digoxin \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Doxazosin mesilate \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2232,9 +2440,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Losartan potassium \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Losartan potassium \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2264,12 +2472,28 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alimentary tract and metabolism \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory system \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Respiratory system \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2280,9 +2504,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cimetidine \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Respiratory system \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2296,11 +2520,27 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Loperamide hydrochloride \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Respiratory system \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Budesonide \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2329,8 +2569,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Dermatologicals \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2344,9 +2584,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Clobetasol propionate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dermatologicals \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2360,12 +2600,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dermatologicals \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2376,11 +2616,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory system \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Dermatologicals \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } @@ -2392,11 +2632,11 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Guaifenesin \cell -\pard\intbl\qc\fs18 0 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Clobetasol propionate \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } diff --git a/tests/testthat/_snaps/tsicm03/tsicm03.rtf b/tests/testthat/_snaps/tsicm03/tsicm03.rtf old mode 100755 new mode 100644 index 9c08c758..5f7109ad --- a/tests/testthat/_snaps/tsicm03/tsicm03.rtf +++ b/tests/testthat/_snaps/tsicm03/tsicm03.rtf @@ -20,11 +20,43 @@ { \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2854 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8652 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10584 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4786 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6719 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8652 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10584 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 ATC Level 2 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4786 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 ATC Level 3 \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -40,9 +72,9 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li540\fi0 ATC Level 4 \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell @@ -56,12 +88,12 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Standardized Medication Name \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=185 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li810\fi0 Standardized Medication Name, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=182 \cell \row } @@ -72,12 +104,60 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Uncoded \cell -\pard\intbl\qc\fs18 34 (64.2%) \cell -\pard\intbl\qc\fs18 35 (47.9%) \cell -\pard\intbl\qc\fs18 69 (54.8%) \cell -\pard\intbl\qc\fs18 34 (57.6%) \cell -\pard\intbl\qc\fs18 103 (55.7%) \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 concomitant medication \cell +\pard\intbl\qc\fs18 42 (62.7%) \cell +\pard\intbl\qc\fs18 39 (76.5%) \cell +\pard\intbl\qc\fs18 81 (68.6%) \cell +\pard\intbl\qc\fs18 37 (57.8%) \cell +\pard\intbl\qc\fs18 118 (64.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell \row } @@ -88,12 +168,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocortisone, topical \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 23 (18.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 27 (14.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell \row } @@ -104,12 +184,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cortisone \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 16 (8.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell \row } @@ -120,12 +200,60 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: benadryl \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 14 (7.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrocortisone, topical \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 14 (27.5%) \cell +\pard\intbl\qc\fs18 23 (19.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 27 (14.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cortisone \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 17 (9.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: benadryl \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: claritin \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 10 (5.5%) \cell \row } @@ -153,11 +281,59 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -168,12 +344,12 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hydrocortisone \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Hydrocortisone \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } diff --git a/tests/testthat/_snaps/tsicm04/tsicm04.rtf b/tests/testthat/_snaps/tsicm04/tsicm04.rtf old mode 100755 new mode 100644 index fe34412e..1fa034a6 --- a/tests/testthat/_snaps/tsicm04/tsicm04.rtf +++ b/tests/testthat/_snaps/tsicm04/tsicm04.rtf @@ -20,11 +20,43 @@ { \trowd \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2854 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8652 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10584 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4786 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6719 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8652 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10584 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 ATC Level 2 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4786 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 ATC Level 3 \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -40,9 +72,9 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li540\fi0 ATC Level 4 \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell @@ -56,12 +88,12 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Base Preferred Term \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=185 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li810\fi0 Base Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=182 \cell \row } @@ -72,12 +104,60 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Uncoded \cell -\pard\intbl\qc\fs18 34 (64.2%) \cell -\pard\intbl\qc\fs18 35 (47.9%) \cell -\pard\intbl\qc\fs18 69 (54.8%) \cell -\pard\intbl\qc\fs18 34 (57.6%) \cell -\pard\intbl\qc\fs18 103 (55.7%) \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 concomitant medication \cell +\pard\intbl\qc\fs18 42 (62.7%) \cell +\pard\intbl\qc\fs18 39 (76.5%) \cell +\pard\intbl\qc\fs18 81 (68.6%) \cell +\pard\intbl\qc\fs18 37 (57.8%) \cell +\pard\intbl\qc\fs18 118 (64.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell \row } @@ -88,12 +168,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocortisone, topical \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 12 (16.4%) \cell -\pard\intbl\qc\fs18 23 (18.3%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 27 (14.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell \row } @@ -104,12 +184,12 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cortisone \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 16 (8.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 36 (53.7%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 71 (60.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\pard\intbl\qc\fs18 107 (58.8%) \cell \row } @@ -120,12 +200,60 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: benadryl \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 14 (7.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrocortisone, topical \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 14 (27.5%) \cell +\pard\intbl\qc\fs18 23 (19.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 27 (14.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cortisone \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 17 (9.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: benadryl \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: claritin \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 10 (5.5%) \cell \row } @@ -153,11 +281,59 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Systemic hormonal preparations, excl. \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } @@ -168,12 +344,12 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6719 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8652 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hydrocortisone \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Hydrocortisone \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } diff --git a/tests/testthat/_snaps/tsicm05/tsicm05.rtf b/tests/testthat/_snaps/tsicm05/tsicm05.rtf old mode 100755 new mode 100644 index b7682be1..425abdff --- a/tests/testthat/_snaps/tsicm05/tsicm05.rtf +++ b/tests/testthat/_snaps/tsicm05/tsicm05.rtf @@ -3,11 +3,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2854 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3393 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5220 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7047 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8874 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10700 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSICM05:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -19,12 +19,44 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2854 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8652 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10584 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3393 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5220 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7047 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8874 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10700 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 ATC Level 2 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5220 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7047 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8874 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 ATC Level 3 \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -35,14 +67,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li540\fi0 ATC Level 4 \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell @@ -51,43 +83,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Standardized Medication Name \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=185 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li720\fi0 Standardized Medication Name, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=182 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 prior medication \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 56 (76.7%) \cell -\pard\intbl\qc\fs18 99 (78.6%) \cell -\pard\intbl\qc\fs18 49 (83.1%) \cell -\pard\intbl\qc\fs18 148 (80.0%) \cell +\pard\intbl\qc\fs18 53 (79.1%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 91 (77.1%) \cell +\pard\intbl\qc\fs18 55 (85.9%) \cell +\pard\intbl\qc\fs18 146 (80.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -99,719 +131,703 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Uncoded \cell -\pard\intbl\qc\fs18 42 (79.2%) \cell -\pard\intbl\qc\fs18 54 (74.0%) \cell -\pard\intbl\qc\fs18 96 (76.2%) \cell -\pard\intbl\qc\fs18 47 (79.7%) \cell -\pard\intbl\qc\fs18 143 (77.3%) \cell +\pard\intbl\qc\fs18 52 (77.6%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 90 (76.3%) \cell +\pard\intbl\qc\fs18 53 (82.8%) \cell +\pard\intbl\qc\fs18 143 (78.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin e \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 10 (13.7%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 12 (20.3%) \cell -\pard\intbl\qc\fs18 30 (16.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 52 (77.6%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 90 (76.3%) \cell +\pard\intbl\qc\fs18 53 (82.8%) \cell +\pard\intbl\qc\fs18 143 (78.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: multivitamin \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 19 (15.1%) \cell -\pard\intbl\qc\fs18 9 (15.3%) \cell -\pard\intbl\qc\fs18 28 (15.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 52 (77.6%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 90 (76.3%) \cell +\pard\intbl\qc\fs18 53 (82.8%) \cell +\pard\intbl\qc\fs18 143 (78.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: multivitamins \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 19 (10.3%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 52 (77.6%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 90 (76.3%) \cell +\pard\intbl\qc\fs18 53 (82.8%) \cell +\pard\intbl\qc\fs18 143 (78.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin c \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 15 (8.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin e \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 31 (17.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: synthroid \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 10 (5.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: multivitamin \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 30 (16.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 10 (5.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: multivitamins \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 18 (9.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: timoptic \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 9 (4.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin c \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 18 (9.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: centrum silver \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: synthroid \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 12 (6.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ibuprofen \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 10 (5.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: motrin \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: metamucil \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 8 (4.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ativan \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: timoptic \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 7 (3.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ecotrin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin b12 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 7 (3.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: estrogen nos \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: advil \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ginkgo biloba \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: centrum \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: metamucil \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: estrogen nos \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: provera \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: motrin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zestril \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: provera \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zocor \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: claritin \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 5 (2.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: advil \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ibuprofen \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 5 (2.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: asa \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ocuvite \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 5 (2.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: claritin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: potassium \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 5 (2.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: dyazide \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: asa \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin b12 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ativan \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zinc \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: dyazide \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: betagan \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ecotrin \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: centrum \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: furosemide \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ginkgo biloba \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: garlic \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zestril \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lopid \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zinc \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: monopril \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: centrum silver \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ocuvite \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: garlic \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: potassium \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: monopril \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prilosec \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prilosec \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prinivil \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prinivil \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tums \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zocor \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamins \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: accupril \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: accupril \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: altace \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: acetaminophen \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: aspirin (e.c.) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: altace \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: b complex \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: aspirin (e.c.) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: benadryl \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: b complex \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: betacarotene \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: benadryl \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: betagan \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: betacarotene \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: bufferin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: bufferin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: capoten \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -819,31 +835,31 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: calcium carbonate \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: chloral hydrate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: capoten \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: excedrin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -851,15 +867,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: chloral hydrate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: fosamax \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -867,15 +883,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: excedrin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: furosemide \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -883,15 +899,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: glyburide \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: glyburide \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -899,47 +915,47 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: herbal preparation \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrochlorothiazide \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrochlorothiazide \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrocortisone, topical \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocortisone, topical \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hytrin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -947,15 +963,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hytrin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: iron \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -963,15 +979,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lisinopril \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lisinopril \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -979,63 +995,63 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: milk of magnesia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lopid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: mylanta \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lorazepam \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prednisone \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: mylanta \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: procardia \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: seldane \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -1043,174 +1059,174 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: propine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: trusopt \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: relafen \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tums \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: theragran-m \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin d \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: trusopt \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamins \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin b \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: acetaminophen \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin d \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: aerobid \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: aerobid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: alphagan \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: albuterol \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: amoxicillin \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: alphagan \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ampicillin \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ampicillin \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: anacin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: anti-oxidant \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ascriptin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1219,14 +1235,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ascriptin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: beconase \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1235,46 +1251,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: beconase \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: benzalkonium chloride \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: benzalkonium chloride \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: calcium carbonate \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: calcium magnesium \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: calcium magnesium \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1283,30 +1299,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: central-vite \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: central-vite \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: charcoal, activated \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: charcoal, activated \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1315,14 +1331,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cipro \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cipro \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1331,14 +1347,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cod-liver oil \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cod-liver oil \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1347,30 +1363,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: daypro \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: colestid \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: debrox \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: debrox \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1379,30 +1395,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: dhea \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: desonide \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diabeta \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diabeta \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1411,14 +1427,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diabinese \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diabinese \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1427,30 +1443,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diprolene cream \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diltiazem \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: dipyridamole \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: dipyridamole \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1459,14 +1475,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: docusate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: docusate \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1475,14 +1491,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: docusate sodium \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: docusate sodium \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1491,94 +1507,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: estradiol \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: estrace \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: eucerin creme \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: estradiol \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ex-lax \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: eucerin creme \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: feldene \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ex-lax \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: fibre, dietary \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: feldene \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: folic acid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ferrous gluconate \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1587,14 +1603,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: fosamax \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: folic acid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1603,14 +1619,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: garamycin ophthalmic \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: garamycin ophthalmic \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1619,30 +1635,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ginseng \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ginseng \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: glucotrol \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: glucotrol \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1651,14 +1667,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hismanal \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: herbal preparation \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1667,30 +1683,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: homeopatic preparation \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: homeopatic preparation \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: humulin n \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: humulin n \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1699,14 +1715,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrochlorothiazide with triamterene \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrochlorothiazide with triamterene \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1715,30 +1731,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: indocin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hygroton \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: influenza virus vaccine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: indocin \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1747,13 +1763,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: iron \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: influenza virus vaccine \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1763,14 +1779,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: k-dur \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: k-dur \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1779,14 +1795,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: keflex \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: keflex \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1795,14 +1811,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: levobunolol \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lac-hydrin \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: levobunolol \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1811,14 +1843,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: levothroid \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: levothroid \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1827,46 +1859,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: levoxine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: levoxine \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: levoxyl \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: levoxyl \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lopressor \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lodine \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1875,14 +1907,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lorazepam \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lopressor \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1891,14 +1923,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lotensin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: maxzide \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1907,13 +1939,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: maxzide \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: meclizine \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1923,62 +1955,78 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: meclizine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: medroxyprogesterone \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: medroxyprogesterone \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: metrogel \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: metrogel \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: mevacor \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: minerals nos \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: milk of magnesia \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: minerals nos \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1987,30 +2035,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: multivit \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: multivit \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: nasacort \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: naprosyn \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2019,14 +2067,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: nasal spray \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: nasal spray \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2035,30 +2083,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: neptazane \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: niacin \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: nitro patch \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: nitro patch \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2067,14 +2115,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: nitrodisc \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: nitrodisc \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2083,14 +2131,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: nitroglycerin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: nitroglycerin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2099,14 +2147,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ocupress \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: os-cal \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2115,30 +2163,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: papaya \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: papaya \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: perdiem \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: perdiem \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2147,14 +2195,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: persantine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: peri-colace \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2163,46 +2211,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pilocarpine hydrochloride \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: persantine \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pilostat \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pilostat \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pravastatin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prednisone \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2211,14 +2259,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: premphase \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: premphase \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2227,30 +2275,78 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: promethazine hcl w/codeine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prempro \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: propulsid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prenatal \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: promethazine hcl w/codeine \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: propine \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: propulsid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2259,30 +2355,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: psorcon \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pseudo-chlor \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: psorcon \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: psyllium hydrophilic mucilloid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: psyllium hydrophilic mucilloid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2291,14 +2403,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: quercetin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: quercetin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2307,14 +2419,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: quinamm \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: quinamm \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2323,14 +2435,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: quinapril \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: quinine sulfate \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: relafen \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2339,30 +2467,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: quinine sulfate \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: riopan \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: stresstabs \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: robitussin-dm \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: stresstabs \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2371,14 +2515,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sudafed \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sudafed \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2387,14 +2531,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sulindac \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sulfacetamide \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sulindac \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2403,14 +2563,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: surfak \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: surfak \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2419,14 +2579,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ticlid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tears naturale \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2435,14 +2595,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: timolol maleate \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: theragran-m \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2451,30 +2611,62 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: triamcinolone \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ticlid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: timolol maleate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: triamcinolone \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol extra strength \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: trilisate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2483,14 +2675,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol w/codeine no. 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol w/codeine no. 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2499,14 +2691,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ultram \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vancenase \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2515,13 +2707,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin a \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vasotec \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -2531,14 +2723,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin b6 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin a \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2547,13 +2739,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamins with minerals \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin b \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -2563,14 +2755,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zephrex \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamins with minerals \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2579,14 +2771,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zestoretic \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zephrex \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2595,11 +2787,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zestoretic \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2611,75 +2819,123 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 26 (14.1%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 28 (15.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acetylsalicylic acid \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 14 (23.7%) \cell -\pard\intbl\qc\fs18 25 (13.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 28 (15.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alprazolam \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 28 (15.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 28 (15.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Acetylsalicylic acid \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 15 (23.4%) \cell +\pard\intbl\qc\fs18 27 (14.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Alprazolam \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sumatriptan \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Sumatriptan \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2691,94 +2947,110 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alimentary tract and metabolism \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 19 (10.3%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 20 (11.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Calcium \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 13 (7.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 20 (11.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Simeticone \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 20 (11.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Algeldrate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 20 (11.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Calcium carbonate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Calcium \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 16 (8.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Metformin hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Loperamide hydrochloride \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Loperamide hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2787,14 +3059,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Metformin hydrochloride \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Simeticone \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2803,11 +3075,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2819,43 +3091,91 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Genito urinary system and sex hormones \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 12 (6.5%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 14 (7.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Estrogens conjugated \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 12 (6.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 14 (7.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 14 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 14 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Estrogens conjugated \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 14 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2867,75 +3187,171 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiovascular system \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 9 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 9 (4.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Digoxin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 9 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 9 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Digoxin \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fluvastatin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Nifedipine \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nifedipine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Doxazosin mesilate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Felodipine \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Fluvastatin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Losartan potassium \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2947,43 +3363,91 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory system \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Naproxen sodium \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Respiratory system \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Respiratory system \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Respiratory system \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Naproxen sodium \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2995,43 +3459,91 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Antineoplastic and immunomodulating agents \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Antineoplastic and immunomodulating agents \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Leuprorelin acetate \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Antineoplastic and immunomodulating agents \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Antineoplastic and immunomodulating agents \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Leuprorelin acetate \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -3043,14 +3555,62 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blood and blood forming organs \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blood and blood forming organs \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Blood and blood forming organs \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Blood and blood forming organs \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -3059,14 +3619,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Ferrous sulfate \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Ferrous sulfate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -3075,11 +3635,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2854 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8652 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10584 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3393 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5220 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7047 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8874 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10700 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -3091,11 +3651,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsicm06/tsicm06.rtf b/tests/testthat/_snaps/tsicm06/tsicm06.rtf old mode 100755 new mode 100644 index fd07b8f6..23301de5 --- a/tests/testthat/_snaps/tsicm06/tsicm06.rtf +++ b/tests/testthat/_snaps/tsicm06/tsicm06.rtf @@ -3,11 +3,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2854 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3393 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5220 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7047 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8874 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10700 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSICM06:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -19,12 +19,44 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2854 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8652 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10584 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3393 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5220 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7047 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8874 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10700 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 ATC Level 2 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5220 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7047 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8874 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 ATC Level 3 \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -35,14 +67,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr ATC Level 1 \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li540\fi0 ATC Level 4 \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell @@ -51,43 +83,43 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Base Preferred Term \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=185 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li720\fi0 Base Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=182 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 prior medication \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 56 (76.7%) \cell -\pard\intbl\qc\fs18 99 (78.6%) \cell -\pard\intbl\qc\fs18 49 (83.1%) \cell -\pard\intbl\qc\fs18 148 (80.0%) \cell +\pard\intbl\qc\fs18 53 (79.1%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 91 (77.1%) \cell +\pard\intbl\qc\fs18 55 (85.9%) \cell +\pard\intbl\qc\fs18 146 (80.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -99,719 +131,703 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Uncoded \cell -\pard\intbl\qc\fs18 42 (79.2%) \cell -\pard\intbl\qc\fs18 54 (74.0%) \cell -\pard\intbl\qc\fs18 96 (76.2%) \cell -\pard\intbl\qc\fs18 47 (79.7%) \cell -\pard\intbl\qc\fs18 143 (77.3%) \cell +\pard\intbl\qc\fs18 52 (77.6%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 90 (76.3%) \cell +\pard\intbl\qc\fs18 53 (82.8%) \cell +\pard\intbl\qc\fs18 143 (78.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin e \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 10 (13.7%) \cell -\pard\intbl\qc\fs18 18 (14.3%) \cell -\pard\intbl\qc\fs18 12 (20.3%) \cell -\pard\intbl\qc\fs18 30 (16.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 52 (77.6%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 90 (76.3%) \cell +\pard\intbl\qc\fs18 53 (82.8%) \cell +\pard\intbl\qc\fs18 143 (78.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: multivitamin \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 11 (15.1%) \cell -\pard\intbl\qc\fs18 19 (15.1%) \cell -\pard\intbl\qc\fs18 9 (15.3%) \cell -\pard\intbl\qc\fs18 28 (15.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 52 (77.6%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 90 (76.3%) \cell +\pard\intbl\qc\fs18 53 (82.8%) \cell +\pard\intbl\qc\fs18 143 (78.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: multivitamins \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 19 (10.3%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 52 (77.6%) \cell +\pard\intbl\qc\fs18 38 (74.5%) \cell +\pard\intbl\qc\fs18 90 (76.3%) \cell +\pard\intbl\qc\fs18 53 (82.8%) \cell +\pard\intbl\qc\fs18 143 (78.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin c \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 15 (8.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin e \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 31 (17.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: synthroid \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 10 (5.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: multivitamin \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\pard\intbl\qc\fs18 30 (16.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 10 (5.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: multivitamins \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 13 (11.0%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 18 (9.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: timoptic \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 9 (4.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin c \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 18 (9.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: centrum silver \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: synthroid \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 12 (6.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ibuprofen \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 10 (5.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: motrin \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: metamucil \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 8 (4.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ativan \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: timoptic \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 7 (3.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ecotrin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin b12 \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 7 (3.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: estrogen nos \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: advil \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ginkgo biloba \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: centrum \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: metamucil \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: estrogen nos \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: provera \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: motrin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zestril \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: provera \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zocor \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: claritin \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 5 (2.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: advil \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ibuprofen \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 5 (2.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: asa \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ocuvite \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 5 (2.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: claritin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: potassium \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 5 (2.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: dyazide \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 4 (3.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: asa \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin b12 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ativan \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zinc \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: dyazide \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: betagan \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ecotrin \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: centrum \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: furosemide \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ginkgo biloba \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: garlic \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zestril \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lopid \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zinc \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: monopril \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: centrum silver \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ocuvite \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: garlic \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: potassium \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: monopril \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prilosec \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prilosec \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prinivil \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prinivil \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tums \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zocor \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell \pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamins \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: accupril \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: accupril \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: altace \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: acetaminophen \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: aspirin (e.c.) \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: altace \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: b complex \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: aspirin (e.c.) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: benadryl \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: b complex \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: betacarotene \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: benadryl \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: betagan \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: betacarotene \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: bufferin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: bufferin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: capoten \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -819,31 +835,31 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: calcium carbonate \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: chloral hydrate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: capoten \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: excedrin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -851,15 +867,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: chloral hydrate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: fosamax \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -867,15 +883,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: excedrin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: furosemide \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -883,15 +899,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: glyburide \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: glyburide \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -899,47 +915,47 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: herbal preparation \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrochlorothiazide \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrochlorothiazide \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrocortisone, topical \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrocortisone, topical \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hytrin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -947,15 +963,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hytrin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: iron \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -963,15 +979,15 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lisinopril \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lisinopril \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -979,63 +995,63 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: milk of magnesia \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lopid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: mylanta \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lorazepam \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: prednisone \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: mylanta \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: procardia \cell -\pard\intbl\qc\fs18 2 (3.8%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: seldane \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row @@ -1043,174 +1059,174 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: propine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: trusopt \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: relafen \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tums \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: theragran-m \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin d \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: trusopt \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamins \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin b \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: acetaminophen \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin d \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: aerobid \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: aerobid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: alphagan \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: albuterol \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: amoxicillin \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: alphagan \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ampicillin \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ampicillin \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: anacin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: anti-oxidant \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ascriptin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1219,14 +1235,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ascriptin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: beconase \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1235,46 +1251,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: beconase \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: benzalkonium chloride \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: benzalkonium chloride \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: calcium carbonate \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: calcium magnesium \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: calcium magnesium \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1283,30 +1299,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: central-vite \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: central-vite \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: charcoal, activated \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: charcoal, activated \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1315,14 +1331,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cipro \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cipro \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1331,14 +1347,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: cod-liver oil \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: cod-liver oil \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1347,30 +1363,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: daypro \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: colestid \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: debrox \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: debrox \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1379,30 +1395,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: dhea \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: desonide \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diabeta \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diabeta \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1411,14 +1427,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diabinese \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diabinese \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1427,30 +1443,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: diprolene cream \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: diltiazem \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: dipyridamole \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: dipyridamole \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1459,14 +1475,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: docusate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: docusate \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1475,14 +1491,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: docusate sodium \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: docusate sodium \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1491,94 +1507,94 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: estradiol \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: estrace \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: eucerin creme \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: estradiol \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ex-lax \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: eucerin creme \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: feldene \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ex-lax \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: fibre, dietary \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: feldene \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: folic acid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ferrous gluconate \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1587,14 +1603,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: fosamax \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: folic acid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1603,14 +1619,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: garamycin ophthalmic \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: garamycin ophthalmic \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1619,30 +1635,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ginseng \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ginseng \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: glucotrol \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: glucotrol \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1651,14 +1667,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hismanal \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: herbal preparation \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1667,30 +1683,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: homeopatic preparation \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: homeopatic preparation \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: humulin n \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: humulin n \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1699,14 +1715,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: hydrochlorothiazide with triamterene \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hydrochlorothiazide with triamterene \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1715,30 +1731,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: indocin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: hygroton \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: influenza virus vaccine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: indocin \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1747,13 +1763,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: iron \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: influenza virus vaccine \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1763,14 +1779,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: k-dur \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: k-dur \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1779,14 +1795,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: keflex \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: keflex \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1795,14 +1811,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: levobunolol \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lac-hydrin \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: levobunolol \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1811,14 +1843,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: levothroid \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: levothroid \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1827,46 +1859,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: levoxine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: levoxine \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: levoxyl \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: levoxyl \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lopressor \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lodine \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1875,14 +1907,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lorazepam \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: lopressor \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1891,14 +1923,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: lotensin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: maxzide \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1907,13 +1939,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: maxzide \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: meclizine \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -1923,62 +1955,78 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: meclizine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: medroxyprogesterone \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: medroxyprogesterone \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: metrogel \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: metrogel \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: mevacor \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: minerals nos \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: milk of magnesia \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: minerals nos \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -1987,30 +2035,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: multivit \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: multivit \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: nasacort \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: naprosyn \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2019,14 +2067,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: nasal spray \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: nasal spray \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2035,30 +2083,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: neptazane \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: niacin \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: nitro patch \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: nitro patch \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2067,14 +2115,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: nitrodisc \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: nitrodisc \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2083,14 +2131,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: nitroglycerin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: nitroglycerin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2099,14 +2147,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ocupress \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: os-cal \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2115,30 +2163,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: papaya \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: papaya \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: perdiem \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: perdiem \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2147,14 +2195,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: persantine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: peri-colace \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2163,46 +2211,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pilocarpine hydrochloride \cell -\pard\intbl\qc\fs18 0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: persantine \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pilostat \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pilostat \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: pravastatin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prednisone \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2211,14 +2259,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: premphase \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: premphase \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2227,30 +2275,78 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: promethazine hcl w/codeine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prempro \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: propulsid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: prenatal \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: promethazine hcl w/codeine \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: propine \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: propulsid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2259,30 +2355,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: psorcon \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: pseudo-chlor \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: psorcon \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: psyllium hydrophilic mucilloid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: psyllium hydrophilic mucilloid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2291,14 +2403,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: quercetin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: quercetin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2307,14 +2419,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: quinamm \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: quinamm \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2323,14 +2435,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: quinapril \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: quinine sulfate \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: relafen \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2339,30 +2467,46 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: quinine sulfate \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: riopan \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: stresstabs \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: robitussin-dm \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: stresstabs \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2371,14 +2515,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sudafed \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sudafed \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2387,14 +2531,30 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: sulindac \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sulfacetamide \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: sulindac \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2403,14 +2563,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: surfak \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: surfak \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2419,14 +2579,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ticlid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tears naturale \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2435,14 +2595,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: timolol maleate \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: theragran-m \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2451,30 +2611,62 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: triamcinolone \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: ticlid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: timolol maleate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: triamcinolone \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol extra strength \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: trilisate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2483,14 +2675,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: tylenol w/codeine no. 4 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: tylenol w/codeine no. 4 \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2499,14 +2691,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: ultram \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vancenase \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2515,13 +2707,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin a \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vasotec \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -2531,14 +2723,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamin b6 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin a \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2547,13 +2739,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: vitamins with minerals \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamin b \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell @@ -2563,14 +2755,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zephrex \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: vitamins with minerals \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2579,14 +2771,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: zestoretic \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zephrex \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2595,11 +2787,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Uncoded: zestoretic \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2611,75 +2819,123 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 15 (25.4%) \cell -\pard\intbl\qc\fs18 26 (14.1%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 28 (15.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acetylsalicylic acid \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 14 (23.7%) \cell -\pard\intbl\qc\fs18 25 (13.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 28 (15.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alprazolam \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 28 (15.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 16 (25.0%) \cell +\pard\intbl\qc\fs18 28 (15.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Acetylsalicylic acid \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 15 (23.4%) \cell +\pard\intbl\qc\fs18 27 (14.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Alprazolam \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sumatriptan \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Sumatriptan \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2691,94 +2947,110 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Alimentary tract and metabolism \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 12 (9.5%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 19 (10.3%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 20 (11.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Calcium \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 13 (7.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 20 (11.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Simeticone \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 20 (11.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Algeldrate \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Alimentary tract and metabolism \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\pard\intbl\qc\fs18 20 (11.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Calcium carbonate \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Calcium \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\pard\intbl\qc\fs18 16 (8.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Metformin hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Loperamide hydrochloride \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Loperamide hydrochloride \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2787,14 +3059,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Metformin hydrochloride \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Simeticone \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -2803,11 +3075,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2819,43 +3091,91 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Genito urinary system and sex hormones \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 12 (6.5%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 14 (7.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Estrogens conjugated \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 12 (6.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 14 (7.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 14 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Genito urinary system and sex hormones \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 14 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Estrogens conjugated \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 14 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2867,75 +3187,171 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiovascular system \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 7 (5.6%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 9 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 9 (4.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Digoxin \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 9 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Cardiovascular system \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 9 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Digoxin \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\pard\intbl\qc\fs18 4 (2.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fluvastatin \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Nifedipine \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nifedipine \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Doxazosin mesilate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Felodipine \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 2 (1.1%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Fluvastatin \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Losartan potassium \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2947,43 +3363,91 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory system \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Naproxen sodium \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Respiratory system \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (2.4%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Respiratory system \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Respiratory system \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Naproxen sodium \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -2995,43 +3459,91 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Antineoplastic and immunomodulating agents \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Antineoplastic and immunomodulating agents \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Leuprorelin acetate \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Antineoplastic and immunomodulating agents \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 1 (0.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Antineoplastic and immunomodulating agents \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Leuprorelin acetate \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -3043,14 +3555,62 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Blood and blood forming organs \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blood and blood forming organs \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Blood and blood forming organs \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Blood and blood forming organs \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -3059,14 +3619,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2854 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4786 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6719 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8652 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10584 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Ferrous sulfate \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3393 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5220 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7047 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8874 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10700 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Ferrous sulfate \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (0.8%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.5%) \cell @@ -3075,11 +3635,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2854 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8652 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10584 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3393 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5220 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7047 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8874 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10700 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -3091,11 +3651,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2854 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4786 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6719 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8652 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10584 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3393 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5220 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7047 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8874 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10700 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsicm07/tsicm07.rtf b/tests/testthat/_snaps/tsicm07/tsicm07.rtf old mode 100755 new mode 100644 index 6e939cae..f4776570 --- a/tests/testthat/_snaps/tsicm07/tsicm07.rtf +++ b/tests/testthat/_snaps/tsicm07/tsicm07.rtf @@ -3,11 +3,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2811 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4789 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6767 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8954 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10723 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3401 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9101 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10801 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSICM07:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -19,12 +19,60 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2811 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4789 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6767 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8954 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10723 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3401 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5301 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7001 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9101 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10801 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Interest Category \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 ATC Level 1 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 ATC Level 2 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9101 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li540\fi0 ATC Level 3 \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -35,14 +83,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Interest Category \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li720\fi0 ATC Level 4 \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell @@ -51,59 +99,123 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4789 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6767 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10723 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Standardized Medication Name \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=185 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li900\fi0 Standardized Medication Name, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=182 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Steroid \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hydrocortisone \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Hydrocortisone \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -115,43 +227,107 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4789 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6767 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10723 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acetylsalicylic acid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Acetylsalicylic acid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2811 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4789 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6767 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8954 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10723 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3401 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9101 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10801 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -163,11 +339,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsicm08/tsicm08.rtf b/tests/testthat/_snaps/tsicm08/tsicm08.rtf old mode 100755 new mode 100644 index 3a62011d..2b7c23a1 --- a/tests/testthat/_snaps/tsicm08/tsicm08.rtf +++ b/tests/testthat/_snaps/tsicm08/tsicm08.rtf @@ -3,11 +3,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2811 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4789 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6767 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8954 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10723 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3401 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9101 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10801 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSICM08:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -19,12 +19,60 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2811 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4789 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6767 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8954 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10723 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3401 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5301 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7001 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9101 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10801 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Interest Category \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 ATC Level 1 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 ATC Level 2 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9101 +\clmgf\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clmrg\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li540\fi0 ATC Level 3 \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -35,14 +83,14 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Interest Category \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li720\fi0 ATC Level 4 \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell @@ -51,59 +99,123 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4789 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6767 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10723 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Base Preferred Term \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=185 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li900\fi0 Base Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=182 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Steroid \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Systemic hormonal preparations, excl. \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hydrocortisone \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 16 (12.7%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 17 (9.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Hydrocortisone \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -115,43 +227,107 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Acetylsalicylic Acid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Nervous system \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2811 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4789 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6767 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8954 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10723 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Acetylsalicylic acid \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3401 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5301 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7001 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9101 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10801 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li987\fi-87 Acetylsalicylic acid \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 1 (0.8%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell \pard\intbl\qc\fs18 2 (1.1%) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2811 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4789 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6767 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8954 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10723 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3401 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9101 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10801 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -163,11 +339,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2811 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4789 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6767 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8954 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10723 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3401 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5301 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7001 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9101 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10801 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsidem01/tsidem01.rtf b/tests/testthat/_snaps/tsidem01/tsidem01.rtf old mode 100755 new mode 100644 index 85f15ecc..f4494e24 --- a/tests/testthat/_snaps/tsidem01/tsidem01.rtf +++ b/tests/testthat/_snaps/tsidem01/tsidem01.rtf @@ -36,8 +36,8 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell \row @@ -92,8 +92,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Male \cell -\pard\intbl\qc\fs18 44 (52.4%) \cell \pard\intbl\qc\fs18 34 (40.5%) \cell +\pard\intbl\qc\fs18 44 (52.4%) \cell \pard\intbl\qc\fs18 33 (38.4%) \cell \pard\intbl\qc\fs18 111 (43.7%) \cell \row @@ -106,41 +106,13 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Female \cell -\pard\intbl\qc\fs18 40 (47.6%) \cell \pard\intbl\qc\fs18 50 (59.5%) \cell +\pard\intbl\qc\fs18 40 (47.6%) \cell \pard\intbl\qc\fs18 53 (61.6%) \cell \pard\intbl\qc\fs18 143 (56.3%) \cell \row } -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Intersex \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Unknown \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\row -} - { \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 @@ -161,7 +133,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Age (years) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -190,8 +162,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 74.4 (7.89) \cell \pard\intbl\qc\fs18 75.7 (8.29) \cell +\pard\intbl\qc\fs18 74.4 (7.89) \cell \pard\intbl\qc\fs18 75.2 (8.59) \cell \pard\intbl\qc\fs18 75.1 (8.25) \cell \row @@ -204,9 +176,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 76.0 \cell \pard\intbl\qc\fs18 77.5 \cell \pard\intbl\qc\fs18 76.0 \cell +\pard\intbl\qc\fs18 76.0 \cell \pard\intbl\qc\fs18 77.0 \cell \row } @@ -218,8 +190,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 56, 88 \cell \pard\intbl\qc\fs18 51, 88 \cell +\pard\intbl\qc\fs18 56, 88 \cell \pard\intbl\qc\fs18 52, 89 \cell \pard\intbl\qc\fs18 51, 89 \cell \row @@ -232,8 +204,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?18 to <65, n (%) \cell -\pard\intbl\qc\fs18 11 (13.1%) \cell \pard\intbl\qc\fs18 8 (9.5%) \cell +\pard\intbl\qc\fs18 11 (13.1%) \cell \pard\intbl\qc\fs18 14 (16.3%) \cell \pard\intbl\qc\fs18 33 (13.0%) \cell \row @@ -246,8 +218,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?65, n (%) \cell -\pard\intbl\qc\fs18 73 (86.9%) \cell \pard\intbl\qc\fs18 76 (90.5%) \cell +\pard\intbl\qc\fs18 73 (86.9%) \cell \pard\intbl\qc\fs18 72 (83.7%) \cell \pard\intbl\qc\fs18 221 (87.0%) \cell \row @@ -260,8 +232,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?65 to <75, n (%) \cell -\pard\intbl\qc\fs18 25 (29.8%) \cell \pard\intbl\qc\fs18 23 (27.4%) \cell +\pard\intbl\qc\fs18 25 (29.8%) \cell \pard\intbl\qc\fs18 24 (27.9%) \cell \pard\intbl\qc\fs18 72 (28.3%) \cell \row @@ -274,8 +246,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?75, n (%) \cell -\pard\intbl\qc\fs18 48 (57.1%) \cell \pard\intbl\qc\fs18 53 (63.1%) \cell +\pard\intbl\qc\fs18 48 (57.1%) \cell \pard\intbl\qc\fs18 48 (55.8%) \cell \pard\intbl\qc\fs18 149 (58.7%) \cell \row @@ -330,8 +302,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 American Indian or Alaska Native \cell -\pard\intbl\qc\fs18 7 (8.3%) \cell \pard\intbl\qc\fs18 13 (15.5%) \cell +\pard\intbl\qc\fs18 7 (8.3%) \cell \pard\intbl\qc\fs18 6 (7.0%) \cell \pard\intbl\qc\fs18 26 (10.2%) \cell \row @@ -358,8 +330,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Black or African American \cell -\pard\intbl\qc\fs18 7 (8.3%) \cell \pard\intbl\qc\fs18 10 (11.9%) \cell +\pard\intbl\qc\fs18 7 (8.3%) \cell \pard\intbl\qc\fs18 10 (11.6%) \cell \pard\intbl\qc\fs18 27 (10.6%) \cell \row @@ -372,8 +344,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs18 10 (11.9%) \cell \pard\intbl\qc\fs18 7 (8.3%) \cell +\pard\intbl\qc\fs18 10 (11.9%) \cell \pard\intbl\qc\fs18 8 (9.3%) \cell \pard\intbl\qc\fs18 25 (9.8%) \cell \row @@ -386,8 +358,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 White \cell -\pard\intbl\qc\fs18 11 (13.1%) \cell \pard\intbl\qc\fs18 10 (11.9%) \cell +\pard\intbl\qc\fs18 11 (13.1%) \cell \pard\intbl\qc\fs18 9 (10.5%) \cell \pard\intbl\qc\fs18 30 (11.8%) \cell \row @@ -400,8 +372,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Multiple \cell -\pard\intbl\qc\fs18 12 (14.3%) \cell \pard\intbl\qc\fs18 9 (10.7%) \cell +\pard\intbl\qc\fs18 12 (14.3%) \cell \pard\intbl\qc\fs18 8 (9.3%) \cell \pard\intbl\qc\fs18 29 (11.4%) \cell \row @@ -414,8 +386,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Not reported \cell -\pard\intbl\qc\fs18 11 (13.1%) \cell \pard\intbl\qc\fs18 7 (8.3%) \cell +\pard\intbl\qc\fs18 11 (13.1%) \cell \pard\intbl\qc\fs18 11 (12.8%) \cell \pard\intbl\qc\fs18 29 (11.4%) \cell \row @@ -428,8 +400,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Unknown \cell -\pard\intbl\qc\fs18 10 (11.9%) \cell \pard\intbl\qc\fs18 6 (7.1%) \cell +\pard\intbl\qc\fs18 10 (11.9%) \cell \pard\intbl\qc\fs18 11 (12.8%) \cell \pard\intbl\qc\fs18 27 (10.6%) \cell \row @@ -442,8 +414,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 5 (6.0%) \cell \pard\intbl\qc\fs18 11 (13.1%) \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell \pard\intbl\qc\fs18 16 (18.6%) \cell \pard\intbl\qc\fs18 32 (12.6%) \cell \row @@ -498,8 +470,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Hispanic or Latino \cell -\pard\intbl\qc\fs18 20 (23.8%) \cell \pard\intbl\qc\fs18 19 (22.6%) \cell +\pard\intbl\qc\fs18 20 (23.8%) \cell \pard\intbl\qc\fs18 18 (20.9%) \cell \pard\intbl\qc\fs18 57 (22.4%) \cell \row @@ -512,8 +484,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Not Hispanic or Latino \cell -\pard\intbl\qc\fs18 26 (31.0%) \cell \pard\intbl\qc\fs18 18 (21.4%) \cell +\pard\intbl\qc\fs18 26 (31.0%) \cell \pard\intbl\qc\fs18 19 (22.1%) \cell \pard\intbl\qc\fs18 63 (24.8%) \cell \row @@ -526,8 +498,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Not reported \cell -\pard\intbl\qc\fs18 15 (17.9%) \cell \pard\intbl\qc\fs18 27 (32.1%) \cell +\pard\intbl\qc\fs18 15 (17.9%) \cell \pard\intbl\qc\fs18 23 (26.7%) \cell \pard\intbl\qc\fs18 65 (25.6%) \cell \row @@ -540,8 +512,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Unknown \cell -\pard\intbl\qc\fs18 23 (27.4%) \cell \pard\intbl\qc\fs18 20 (23.8%) \cell +\pard\intbl\qc\fs18 23 (27.4%) \cell \pard\intbl\qc\fs18 26 (30.2%) \cell \pard\intbl\qc\fs18 69 (27.2%) \cell \row @@ -596,10 +568,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 73.00 (44.004) \cell -\pard\intbl\qc\fs18 75.88 (43.448) \cell -\pard\intbl\qc\fs18 76.66 (42.980) \cell -\pard\intbl\qc\fs18 75.19 (43.332) \cell +\pard\intbl\qc\fs18 75.70 (42.700) \cell +\pard\intbl\qc\fs18 68.73 (45.229) \cell +\pard\intbl\qc\fs18 77.03 (42.697) \cell +\pard\intbl\qc\fs18 73.85 (43.532) \cell \row } @@ -611,8 +583,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell \pard\intbl\qc\fs18 75.50 \cell -\pard\intbl\qc\fs18 73.00 \cell -\pard\intbl\qc\fs18 74.00 \cell +\pard\intbl\qc\fs18 68.50 \cell +\pard\intbl\qc\fs18 83.50 \cell \pard\intbl\qc\fs18 74.50 \cell \row } @@ -624,9 +596,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 3.0, 149.0 \cell -\pard\intbl\qc\fs18 1.0, 147.0 \cell +\pard\intbl\qc\fs18 2.0, 150.0 \cell \pard\intbl\qc\fs18 1.0, 150.0 \cell +\pard\intbl\qc\fs18 1.0, 145.0 \cell \pard\intbl\qc\fs18 1.0, 150.0 \cell \row } @@ -638,10 +610,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 <30, n (%) \cell -\pard\intbl\qc\fs18 22 (26.2%) \cell -\pard\intbl\qc\fs18 17 (20.2%) \cell -\pard\intbl\qc\fs18 13 (15.1%) \cell -\pard\intbl\qc\fs18 52 (20.5%) \cell +\pard\intbl\qc\fs18 16 (19.0%) \cell +\pard\intbl\qc\fs18 23 (27.4%) \cell +\pard\intbl\qc\fs18 16 (18.6%) \cell +\pard\intbl\qc\fs18 55 (21.7%) \cell \row } @@ -652,10 +624,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?30 to <60, n (%) \cell -\pard\intbl\qc\fs18 10 (11.9%) \cell \pard\intbl\qc\fs18 14 (16.7%) \cell -\pard\intbl\qc\fs18 20 (23.3%) \cell -\pard\intbl\qc\fs18 44 (17.3%) \cell +\pard\intbl\qc\fs18 15 (17.9%) \cell +\pard\intbl\qc\fs18 16 (18.6%) \cell +\pard\intbl\qc\fs18 45 (17.7%) \cell \row } @@ -666,10 +638,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?60 to <90, n (%) \cell +\pard\intbl\qc\fs18 19 (22.6%) \cell \pard\intbl\qc\fs18 17 (20.2%) \cell -\pard\intbl\qc\fs18 18 (21.4%) \cell -\pard\intbl\qc\fs18 20 (23.3%) \cell -\pard\intbl\qc\fs18 55 (21.7%) \cell +\pard\intbl\qc\fs18 18 (20.9%) \cell +\pard\intbl\qc\fs18 54 (21.3%) \cell \row } @@ -681,9 +653,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?90, n (%) \cell \pard\intbl\qc\fs18 35 (41.7%) \cell -\pard\intbl\qc\fs18 35 (41.7%) \cell -\pard\intbl\qc\fs18 33 (38.4%) \cell -\pard\intbl\qc\fs18 103 (40.6%) \cell +\pard\intbl\qc\fs18 29 (34.5%) \cell +\pard\intbl\qc\fs18 36 (41.9%) \cell +\pard\intbl\qc\fs18 100 (39.4%) \cell \row } @@ -736,10 +708,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 65.19 (42.011) \cell -\pard\intbl\qc\fs18 86.35 (47.899) \cell -\pard\intbl\qc\fs18 67.51 (43.173) \cell -\pard\intbl\qc\fs18 72.97 (45.249) \cell +\pard\intbl\qc\fs18 69.10 (45.214) \cell +\pard\intbl\qc\fs18 66.55 (45.184) \cell +\pard\intbl\qc\fs18 76.78 (46.180) \cell +\pard\intbl\qc\fs18 70.85 (45.563) \cell \row } @@ -750,10 +722,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 62.50 \cell -\pard\intbl\qc\fs18 96.00 \cell +\pard\intbl\qc\fs18 65.00 \cell +\pard\intbl\qc\fs18 61.50 \cell +\pard\intbl\qc\fs18 75.50 \cell \pard\intbl\qc\fs18 68.00 \cell -\pard\intbl\qc\fs18 70.50 \cell \row } @@ -764,7 +736,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.0, 143.0 \cell +\pard\intbl\qc\fs18 1.0, 150.0 \cell \pard\intbl\qc\fs18 1.0, 150.0 \cell \pard\intbl\qc\fs18 0.0, 150.0 \cell \pard\intbl\qc\fs18 0.0, 150.0 \cell @@ -791,7 +763,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Body mass index (kg/m2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Body mass index (kg/m\super 2\nosupersub ) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -820,10 +792,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 79.63 (45.793) \cell -\pard\intbl\qc\fs18 78.55 (46.331) \cell -\pard\intbl\qc\fs18 70.19 (42.088) \cell -\pard\intbl\qc\fs18 76.07 (44.781) \cell +\pard\intbl\qc\fs18 78.20 (44.292) \cell +\pard\intbl\qc\fs18 75.71 (45.260) \cell +\pard\intbl\qc\fs18 70.30 (45.892) \cell +\pard\intbl\qc\fs18 74.70 (45.102) \cell \row } @@ -834,10 +806,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 78.00 \cell -\pard\intbl\qc\fs18 84.00 \cell -\pard\intbl\qc\fs18 63.50 \cell -\pard\intbl\qc\fs18 75.50 \cell +\pard\intbl\qc\fs18 80.00 \cell +\pard\intbl\qc\fs18 79.00 \cell +\pard\intbl\qc\fs18 65.00 \cell +\pard\intbl\qc\fs18 74.50 \cell \row } @@ -848,10 +820,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1.0, 150.0 \cell -\pard\intbl\qc\fs18 4.0, 150.0 \cell +\pard\intbl\qc\fs18 3.0, 145.0 \cell \pard\intbl\qc\fs18 2.0, 148.0 \cell \pard\intbl\qc\fs18 1.0, 150.0 \cell +\pard\intbl\qc\fs18 1.0, 150.0 \cell \row } @@ -863,9 +835,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Underweight <18.5, n (%) \cell \pard\intbl\qc\fs18 11 (13.1%) \cell -\pard\intbl\qc\fs18 12 (14.3%) \cell -\pard\intbl\qc\fs18 13 (15.1%) \cell -\pard\intbl\qc\fs18 36 (14.2%) \cell +\pard\intbl\qc\fs18 13 (15.5%) \cell +\pard\intbl\qc\fs18 15 (17.4%) \cell +\pard\intbl\qc\fs18 39 (15.4%) \cell \row } @@ -876,10 +848,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Normal \u8805?18.5 to <25, n (%) \cell -\pard\intbl\qc\fs18 4 (4.8%) \cell +\pard\intbl\qc\fs18 3 (3.6%) \cell \pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 6 (2.4%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 7 (2.8%) \cell \row } @@ -891,9 +863,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Overweight \u8805?25 to <30, n (%) \cell \pard\intbl\qc\fs18 2 (2.4%) \cell -\pard\intbl\qc\fs18 6 (7.1%) \cell -\pard\intbl\qc\fs18 2 (2.3%) \cell -\pard\intbl\qc\fs18 10 (3.9%) \cell +\pard\intbl\qc\fs18 4 (4.8%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 9 (3.5%) \cell \row } @@ -904,10 +876,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Obese \u8805?30, n (%) \cell -\pard\intbl\qc\fs18 67 (79.8%) \cell -\pard\intbl\qc\fs18 65 (77.4%) \cell -\pard\intbl\qc\fs18 70 (81.4%) \cell -\pard\intbl\qc\fs18 202 (79.5%) \cell +\pard\intbl\qc\fs18 68 (81.0%) \cell +\pard\intbl\qc\fs18 66 (78.6%) \cell +\pard\intbl\qc\fs18 65 (75.6%) \cell +\pard\intbl\qc\fs18 199 (78.3%) \cell \row } @@ -931,7 +903,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Body surface area (m2) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Body surface area (m\super 2\nosupersub ) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -960,10 +932,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 70.15 (38.549) \cell -\pard\intbl\qc\fs18 80.58 (38.458) \cell -\pard\intbl\qc\fs18 80.12 (47.211) \cell -\pard\intbl\qc\fs18 76.98 (41.769) \cell +\pard\intbl\qc\fs18 74.04 (37.524) \cell +\pard\intbl\qc\fs18 71.25 (43.678) \cell +\pard\intbl\qc\fs18 85.67 (39.333) \cell +\pard\intbl\qc\fs18 77.06 (40.584) \cell \row } @@ -974,10 +946,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 69.50 \cell -\pard\intbl\qc\fs18 87.50 \cell -\pard\intbl\qc\fs18 79.50 \cell -\pard\intbl\qc\fs18 76.00 \cell +\pard\intbl\qc\fs18 74.00 \cell +\pard\intbl\qc\fs18 65.00 \cell +\pard\intbl\qc\fs18 87.00 \cell +\pard\intbl\qc\fs18 74.00 \cell \row } @@ -989,8 +961,8 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell \pard\intbl\qc\fs18 6.0, 150.0 \cell -\pard\intbl\qc\fs18 3.0, 146.0 \cell \pard\intbl\qc\fs18 2.0, 150.0 \cell +\pard\intbl\qc\fs18 8.0, 148.0 \cell \pard\intbl\qc\fs18 2.0, 150.0 \cell \row } @@ -1015,7 +987,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Geographic Region 1, n (%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Region, n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -1043,7 +1015,7 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 North America \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Northern America \cell \pard\intbl\qc\fs18 84 (100.0%) \cell \pard\intbl\qc\fs18 84 (100.0%) \cell \pard\intbl\qc\fs18 86 (100.0%) \cell @@ -1099,7 +1071,7 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4449 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6029 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7609 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 United States of America \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 United States \cell \pard\intbl\qc\fs18 84 (100.0%) \cell \pard\intbl\qc\fs18 84 (100.0%) \cell \pard\intbl\qc\fs18 86 (100.0%) \cell diff --git a/tests/testthat/_snaps/tsidem02/tsidem02.rtf b/tests/testthat/_snaps/tsidem02/tsidem02.rtf old mode 100755 new mode 100644 index 1a5a3873..56d841f0 --- a/tests/testthat/_snaps/tsidem02/tsidem02.rtf +++ b/tests/testthat/_snaps/tsidem02/tsidem02.rtf @@ -36,8 +36,8 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Country/Territory \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell \row @@ -50,10 +50,10 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Site, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=62 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=185 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=84 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=84 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=86 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=254 \cell \row } @@ -63,11 +63,11 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4392 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 North America \cell -\pard\intbl\qc\fs18 64 (100.0%) \cell -\pard\intbl\qc\fs18 62 (100.0%) \cell -\pard\intbl\qc\fs18 59 (100.0%) \cell -\pard\intbl\qc\fs18 185 (100.0%) \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Northern America \cell +\pard\intbl\qc\fs18 84 (100.0%) \cell +\pard\intbl\qc\fs18 84 (100.0%) \cell +\pard\intbl\qc\fs18 86 (100.0%) \cell +\pard\intbl\qc\fs18 254 (100.0%) \cell \row } @@ -77,11 +77,11 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4392 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 United States of America \cell -\pard\intbl\qc\fs18 64 (100.0%) \cell -\pard\intbl\qc\fs18 62 (100.0%) \cell -\pard\intbl\qc\fs18 59 (100.0%) \cell -\pard\intbl\qc\fs18 185 (100.0%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 United States \cell +\pard\intbl\qc\fs18 84 (100.0%) \cell +\pard\intbl\qc\fs18 84 (100.0%) \cell +\pard\intbl\qc\fs18 86 (100.0%) \cell +\pard\intbl\qc\fs18 254 (100.0%) \cell \row } @@ -92,10 +92,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 701 \cell -\pard\intbl\qc\fs18 12 (18.8%) \cell -\pard\intbl\qc\fs18 12 (19.4%) \cell -\pard\intbl\qc\fs18 11 (18.6%) \cell -\pard\intbl\qc\fs18 35 (18.9%) \cell +\pard\intbl\qc\fs18 13 (15.5%) \cell +\pard\intbl\qc\fs18 14 (16.7%) \cell +\pard\intbl\qc\fs18 14 (16.3%) \cell +\pard\intbl\qc\fs18 41 (16.1%) \cell \row } @@ -106,10 +106,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 702 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell \row } @@ -120,10 +120,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 703 \cell -\pard\intbl\qc\fs18 4 (6.2%) \cell -\pard\intbl\qc\fs18 5 (8.1%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 14 (7.6%) \cell +\pard\intbl\qc\fs18 6 (7.1%) \cell +\pard\intbl\qc\fs18 6 (7.1%) \cell +\pard\intbl\qc\fs18 6 (7.0%) \cell +\pard\intbl\qc\fs18 18 (7.1%) \cell \row } @@ -134,10 +134,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 704 \cell -\pard\intbl\qc\fs18 6 (9.4%) \cell -\pard\intbl\qc\fs18 7 (11.3%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 19 (10.3%) \cell +\pard\intbl\qc\fs18 8 (9.5%) \cell +\pard\intbl\qc\fs18 8 (9.5%) \cell +\pard\intbl\qc\fs18 9 (10.5%) \cell +\pard\intbl\qc\fs18 25 (9.8%) \cell \row } @@ -148,10 +148,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 705 \cell -\pard\intbl\qc\fs18 5 (7.8%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 10 (5.4%) \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 6 (7.1%) \cell +\pard\intbl\qc\fs18 5 (5.8%) \cell +\pard\intbl\qc\fs18 16 (6.3%) \cell \row } @@ -162,10 +162,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 706 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell \row } @@ -176,10 +176,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 707 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 1 (0.5%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell \row } @@ -190,10 +190,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 708 \cell -\pard\intbl\qc\fs18 6 (9.4%) \cell -\pard\intbl\qc\fs18 6 (9.7%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell -\pard\intbl\qc\fs18 16 (8.6%) \cell +\pard\intbl\qc\fs18 8 (9.5%) \cell +\pard\intbl\qc\fs18 8 (9.5%) \cell +\pard\intbl\qc\fs18 9 (10.5%) \cell +\pard\intbl\qc\fs18 25 (9.8%) \cell \row } @@ -204,10 +204,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 709 \cell -\pard\intbl\qc\fs18 4 (6.2%) \cell -\pard\intbl\qc\fs18 5 (8.1%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell -\pard\intbl\qc\fs18 15 (8.1%) \cell +\pard\intbl\qc\fs18 7 (8.3%) \cell +\pard\intbl\qc\fs18 7 (8.3%) \cell +\pard\intbl\qc\fs18 7 (8.1%) \cell +\pard\intbl\qc\fs18 21 (8.3%) \cell \row } @@ -218,10 +218,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 710 \cell -\pard\intbl\qc\fs18 8 (12.5%) \cell -\pard\intbl\qc\fs18 7 (11.3%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 22 (11.9%) \cell +\pard\intbl\qc\fs18 10 (11.9%) \cell +\pard\intbl\qc\fs18 10 (11.9%) \cell +\pard\intbl\qc\fs18 11 (12.8%) \cell +\pard\intbl\qc\fs18 31 (12.2%) \cell \row } @@ -232,10 +232,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 711 \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 3 (1.6%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (2.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell \row } @@ -246,10 +246,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 713 \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\pard\intbl\qc\fs18 3 (3.6%) \cell +\pard\intbl\qc\fs18 3 (3.6%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 9 (3.5%) \cell \row } @@ -260,10 +260,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 714 \cell -\pard\intbl\qc\fs18 2 (3.1%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 6 (3.2%) \cell +\pard\intbl\qc\fs18 2 (2.4%) \cell +\pard\intbl\qc\fs18 2 (2.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 6 (2.4%) \cell \row } @@ -274,10 +274,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 715 \cell -\pard\intbl\qc\fs18 2 (3.1%) \cell -\pard\intbl\qc\fs18 2 (3.2%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 5 (2.7%) \cell +\pard\intbl\qc\fs18 3 (3.6%) \cell +\pard\intbl\qc\fs18 2 (2.4%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 8 (3.1%) \cell \row } @@ -288,10 +288,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 716 \cell -\pard\intbl\qc\fs18 8 (12.5%) \cell -\pard\intbl\qc\fs18 4 (6.5%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 19 (10.3%) \cell +\pard\intbl\qc\fs18 8 (9.5%) \cell +\pard\intbl\qc\fs18 8 (9.5%) \cell +\pard\intbl\qc\fs18 8 (9.3%) \cell +\pard\intbl\qc\fs18 24 (9.4%) \cell \row } @@ -302,10 +302,10 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 717 \cell -\pard\intbl\qc\fs18 2 (3.1%) \cell -\pard\intbl\qc\fs18 1 (1.6%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 4 (2.2%) \cell +\pard\intbl\qc\fs18 2 (2.4%) \cell +\pard\intbl\qc\fs18 3 (3.6%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 7 (2.8%) \cell \row } @@ -316,10 +316,10 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5946 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7500 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 718 \cell -\pard\intbl\qc\fs18 3 (4.7%) \cell -\pard\intbl\qc\fs18 3 (4.8%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 8 (4.3%) \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 4 (4.8%) \cell +\pard\intbl\qc\fs18 4 (4.7%) \cell +\pard\intbl\qc\fs18 13 (5.1%) \cell \row } diff --git a/tests/testthat/_snaps/tsiex04/tsiex04.rtf b/tests/testthat/_snaps/tsidem03/tsidem03.rtf old mode 100755 new mode 100644 similarity index 52% rename from tests/testthat/_snaps/tsiex04/tsiex04.rtf rename to tests/testthat/_snaps/tsidem03/tsidem03.rtf index 2beecd10..2cc11039 --- a/tests/testthat/_snaps/tsiex04/tsiex04.rtf +++ b/tests/testthat/_snaps/tsidem03/tsidem03.rtf @@ -6,8 +6,8 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2867 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4411 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5955 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7646 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX04:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7499 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIDEM03:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -20,12 +20,12 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2867 \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4411 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5955 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7646 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7499 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Stratification Factor \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell \row } @@ -34,12 +34,12 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell \row } @@ -48,12 +48,12 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2867 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4411 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Category, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=84 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=84 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=86 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=254 \cell \row } @@ -62,8 +62,8 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Total number of cycles received \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Description of Stratification Factor 1 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -76,82 +76,12 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 12.1 (7.40) \cell -\pard\intbl\qc\fs18 12.9 (6.50) \cell -\pard\intbl\qc\fs18 12.5 (6.88) \cell -\pard\intbl\qc\fs18 12.0 (7.44) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 12.0 \cell -\pard\intbl\qc\fs18 13.0 \cell -\pard\intbl\qc\fs18 13.0 \cell -\pard\intbl\qc\fs18 12.0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0, 24 \cell -\pard\intbl\qc\fs18 0, 24 \cell -\pard\intbl\qc\fs18 0, 24 \cell -\pard\intbl\qc\fs18 0, 24 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of cycles received, n (%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 84 \cell +\pard\intbl\qc\fs18 84 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 254 \cell \row } @@ -160,12 +90,12 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1 to <10 \cell -\pard\intbl\qc\fs18 19 (37.3%) \cell -\pard\intbl\qc\fs18 21 (29.6%) \cell -\pard\intbl\qc\fs18 40 (32.8%) \cell -\pard\intbl\qc\fs18 24 (42.1%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Stratification Factor 1 Value 1 \cell +\pard\intbl\qc\fs18 39 (46.4%) \cell +\pard\intbl\qc\fs18 45 (53.6%) \cell +\pard\intbl\qc\fs18 43 (50.0%) \cell +\pard\intbl\qc\fs18 127 (50.0%) \cell \row } @@ -174,12 +104,12 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 10 to <20 \cell -\pard\intbl\qc\fs18 21 (41.2%) \cell -\pard\intbl\qc\fs18 35 (49.3%) \cell -\pard\intbl\qc\fs18 56 (45.9%) \cell -\pard\intbl\qc\fs18 21 (36.8%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Stratification Factor 1 Value 2 \cell +\pard\intbl\qc\fs18 45 (53.6%) \cell +\pard\intbl\qc\fs18 39 (46.4%) \cell +\pard\intbl\qc\fs18 43 (50.0%) \cell +\pard\intbl\qc\fs18 127 (50.0%) \cell \row } @@ -188,21 +118,7 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?20 \cell -\pard\intbl\qc\fs18 11 (21.6%) \cell -\pard\intbl\qc\fs18 15 (21.1%) \cell -\pard\intbl\qc\fs18 26 (21.3%) \cell -\pard\intbl\qc\fs18 12 (21.1%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -216,8 +132,8 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of cycles received\super a\nosupersub , n (%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Description of Stratification Factor 2 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -230,40 +146,12 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?1 \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 71 (97.3%) \cell -\pard\intbl\qc\fs18 122 (96.8%) \cell -\pard\intbl\qc\fs18 57 (96.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 \cell -\pard\intbl\qc\fs18 49 (92.5%) \cell -\pard\intbl\qc\fs18 69 (94.5%) \cell -\pard\intbl\qc\fs18 118 (93.7%) \cell -\pard\intbl\qc\fs18 56 (94.9%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?3 \cell -\pard\intbl\qc\fs18 46 (86.8%) \cell -\pard\intbl\qc\fs18 69 (94.5%) \cell -\pard\intbl\qc\fs18 115 (91.3%) \cell -\pard\intbl\qc\fs18 54 (91.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 84 \cell +\pard\intbl\qc\fs18 84 \cell +\pard\intbl\qc\fs18 86 \cell +\pard\intbl\qc\fs18 254 \cell \row } @@ -272,12 +160,12 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?5 \cell -\pard\intbl\qc\fs18 43 (81.1%) \cell -\pard\intbl\qc\fs18 66 (90.4%) \cell -\pard\intbl\qc\fs18 109 (86.5%) \cell -\pard\intbl\qc\fs18 48 (81.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Stratification Factor 2 Value 1 \cell +\pard\intbl\qc\fs18 39 (46.4%) \cell +\pard\intbl\qc\fs18 41 (48.8%) \cell +\pard\intbl\qc\fs18 46 (53.5%) \cell +\pard\intbl\qc\fs18 126 (49.6%) \cell \row } @@ -286,12 +174,12 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2867 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4411 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5955 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7646 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?10 \cell -\pard\intbl\qc\fs18 32 (60.4%) \cell -\pard\intbl\qc\fs18 50 (68.5%) \cell -\pard\intbl\qc\fs18 82 (65.1%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Stratification Factor 2 Value 2 \cell +\pard\intbl\qc\fs18 45 (53.6%) \cell +\pard\intbl\qc\fs18 43 (51.2%) \cell +\pard\intbl\qc\fs18 40 (46.5%) \cell +\pard\intbl\qc\fs18 128 (50.4%) \cell \row } @@ -300,7 +188,7 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2867 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4411 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5955 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7646 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7499 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -314,7 +202,7 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsidev01/tsidev01.rtf b/tests/testthat/_snaps/tsidev01/tsidev01.rtf new file mode 100644 index 00000000..66ad93f2 --- /dev/null +++ b/tests/testthat/_snaps/tsidev01/tsidev01.rtf @@ -0,0 +1,1978 @@ +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIDEV01:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2863 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6026 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=86 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=254 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Region: Northern America \cell +\pard\intbl\qc\fs18 24 (25.0%) \cell +\pard\intbl\qc\fs18 21 (29.2%) \cell +\pard\intbl\qc\fs18 12 (14.0%) \cell +\pard\intbl\qc\fs18 57 (22.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 701 \cell +\pard\intbl\qc\fs18 5 (5.2%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 (3.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 5 (5.2%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 9 (3.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 710 \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 5 (6.9%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 9 (3.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 5 (6.9%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 9 (3.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 704 \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 7 (2.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 7 (2.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 716 \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 6 (2.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 6 (2.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 705 \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 5 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 5 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 709 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 718 \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 703 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 708 \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 713 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 715 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 706 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 711 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 714 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subjects with major protocol deviations \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Developed withdrawal criteria but not withdrawn \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Entered but did not satisfy criteria \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received a disallowed concomitant treatment \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Received wrong treatment or incorrect dose \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 702 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 707 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Site: 717 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsidev02/tsidev02.rtf b/tests/testthat/_snaps/tsidev02/tsidev02.rtf new file mode 100644 index 00000000..0c53fee7 --- /dev/null +++ b/tests/testthat/_snaps/tsidev02/tsidev02.rtf @@ -0,0 +1,200 @@ +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2834 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4638 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6098 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7558 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIDEV02:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2834 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4638 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6098 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7558 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4638 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6098 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7558 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2834 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4638 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6098 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7558 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=86 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=254 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4638 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6098 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7558 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects who did not meet inclusion criteria \cell +\pard\intbl\qc\fs18 8 (8.3%) \cell +\pard\intbl\qc\fs18 5 (6.9%) \cell +\pard\intbl\qc\fs18 6 (7.0%) \cell +\pard\intbl\qc\fs18 19 (7.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4638 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6098 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7558 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 INC01 \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 7 (2.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4638 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6098 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7558 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 INC02 \cell +\pard\intbl\qc\fs18 4 (4.2%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 8 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4638 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6098 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7558 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 INC03 \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 5 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4638 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6098 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7558 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4638 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6098 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7558 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects who met exclusion criteria \cell +\pard\intbl\qc\fs18 11 (11.5%) \cell +\pard\intbl\qc\fs18 5 (6.9%) \cell +\pard\intbl\qc\fs18 6 (7.0%) \cell +\pard\intbl\qc\fs18 22 (8.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4638 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6098 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7558 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 EXC01 \cell +\pard\intbl\qc\fs18 5 (5.2%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 6 (7.0%) \cell +\pard\intbl\qc\fs18 13 (5.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2834 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4638 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6098 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7558 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 EXC02 \cell +\pard\intbl\qc\fs18 7 (7.3%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 10 (3.9%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2834 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4638 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6098 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7558 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2834 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4638 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6098 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7558 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsids01/tsids01.rtf b/tests/testthat/_snaps/tsids01/tsids01.rtf old mode 100755 new mode 100644 index ec67f936..6851c7a8 --- a/tests/testthat/_snaps/tsids01/tsids01.rtf +++ b/tests/testthat/_snaps/tsids01/tsids01.rtf @@ -37,7 +37,15 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2785 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Failure to meet eligibility criteria \cell -\pard\intbl\qc\fs18 52 (17.0%) \cell +\pard\intbl\qc\fs18 51 (16.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subject refused to sign informed consent \cell +\pard\intbl\qc\fs18 1 (0.3%) \cell \row } @@ -53,7 +61,23 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2785 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects re-screened \cell -\pard\intbl\qc\fs18 306 \cell +\pard\intbl\qc\fs18 28 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Screening failures \cell +\pard\intbl\qc\fs18 28 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2785 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects randomized \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -69,7 +93,7 @@ \trowd \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2785 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects randomized \cell -\pard\intbl\qc\fs18 185 (60.5%) \cell +\pard\intbl\qc\fs18 182 (59.5%) \cell \row } diff --git a/tests/testthat/_snaps/tsids02/tsids02.rtf b/tests/testthat/_snaps/tsids02/tsids02.rtf old mode 100755 new mode 100644 index efc120e8..f6ee5444 --- a/tests/testthat/_snaps/tsids02/tsids02.rtf +++ b/tests/testthat/_snaps/tsids02/tsids02.rtf @@ -3,361 +3,407 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4175 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5528 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6880 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8350 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10526 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2861 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5264 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7667 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10070 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIDS02:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4175 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5528 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6880 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8350 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10526 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2861 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5264 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7667 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10070 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) 95% CI \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) 95% CI \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10526 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10070 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell \pard\intbl\qc\fs18 \keepn\trhdr N=84 \cell \pard\intbl\qc\fs18 \keepn\trhdr N=84 \cell \pard\intbl\qc\fs18 \keepn\trhdr N=86 \cell \pard\intbl\qc\fs18 \keepn\trhdr N=254 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Analysis set \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects ongoing treatment \cell +\pard\intbl\qc\fs18 20 (23.8%) \cell +\pard\intbl\qc\fs18 16 (19.0%) \cell +\pard\intbl\qc\fs18 15 (17.4%) \cell +\pard\intbl\qc\fs18 51 (20.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Full \cell -\pard\intbl\qc\fs18 84 (100.0%) \cell -\pard\intbl\qc\fs18 84 (100.0%) \cell -\pard\intbl\qc\fs18 86 (100.0%) \cell -\pard\intbl\qc\fs18 254 (100.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Completed treatment \cell +\pard\intbl\qc\fs18 21 (25.0%) \cell +\pard\intbl\qc\fs18 19 (22.6%) \cell +\pard\intbl\qc\fs18 49 (57.0%) \cell +\pard\intbl\qc\fs18 89 (35.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Safety \cell -\pard\intbl\qc\fs18 64 (76.2%) \cell -\pard\intbl\qc\fs18 62 (73.8%) \cell -\pard\intbl\qc\fs18 59 (68.6%) \cell -\pard\intbl\qc\fs18 185 (72.8%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Discontinued treatment \cell +\pard\intbl\qc\fs18 43 (51.2%) \cell +\pard\intbl\qc\fs18 49 (58.3%) \cell +\pard\intbl\qc\fs18 22 (25.6%) \cell +\pard\intbl\qc\fs18 114 (44.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Per protocol \cell -\pard\intbl\qc\fs18 64 (76.2%) \cell -\pard\intbl\qc\fs18 62 (73.8%) \cell -\pard\intbl\qc\fs18 59 (68.6%) \cell -\pard\intbl\qc\fs18 185 (72.8%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Protocol Violation \cell +\pard\intbl\qc\fs18 11 (13.1%) \cell +\pard\intbl\qc\fs18 7 (8.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 18 (7.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lost to Follow-up \cell +\pard\intbl\qc\fs18 3 (3.6%) \cell +\pard\intbl\qc\fs18 7 (8.3%) \cell +\pard\intbl\qc\fs18 6 (7.0%) \cell +\pard\intbl\qc\fs18 16 (6.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects ongoing \cell -\pard\intbl\qc\fs18 18 (21.4%) \cell -\pard\intbl\qc\fs18 15 (17.9%) \cell -\pard\intbl\qc\fs18 14 (16.3%) \cell -\pard\intbl\qc\fs18 47 (18.5%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pregnancy \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 8 (9.5%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 15 (5.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Withdrawal by Subject \cell +\pard\intbl\qc\fs18 4 (4.8%) \cell +\pard\intbl\qc\fs18 6 (7.1%) \cell +\pard\intbl\qc\fs18 4 (4.7%) \cell +\pard\intbl\qc\fs18 14 (5.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Completed treatment \cell -\pard\intbl\qc\fs18 19 (22.6%) \cell -\pard\intbl\qc\fs18 21 (25.0%) \cell -\pard\intbl\qc\fs18 49 (57.0%) \cell -\pard\intbl\qc\fs18 89 (35.0%) \cell -\pard\intbl\qc\fs18 -34.4 (-48.1, -20.6) \cell -\pard\intbl\qc\fs18 -32.0 (-45.9, -18.0) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Adverse Event \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 4 (4.7%) \cell +\pard\intbl\qc\fs18 14 (5.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Discontinued treatment \cell -\pard\intbl\qc\fs18 49 (58.3%) \cell -\pard\intbl\qc\fs18 43 (51.2%) \cell -\pard\intbl\qc\fs18 22 (25.6%) \cell -\pard\intbl\qc\fs18 114 (44.9%) \cell -\pard\intbl\qc\fs18 32.8 (18.7, 46.8) \cell -\pard\intbl\qc\fs18 25.6 (11.5, 39.7) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lack of Efficacy \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 4 (4.7%) \cell +\pard\intbl\qc\fs18 14 (5.5%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Death \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 4 (4.8%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 10 (3.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell -\pard\intbl\qc\fs18 49 (58.3%) \cell -\pard\intbl\qc\fs18 43 (51.2%) \cell -\pard\intbl\qc\fs18 22 (25.6%) \cell -\pard\intbl\qc\fs18 114 (44.9%) \cell -\pard\intbl\qc\fs18 32.8 (18.7, 46.8) \cell -\pard\intbl\qc\fs18 25.6 (11.5, 39.7) \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 7 (8.3%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 13 (5.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects ongoing study \cell +\pard\intbl\qc\fs18 15 (17.9%) \cell +\pard\intbl\qc\fs18 18 (21.4%) \cell +\pard\intbl\qc\fs18 14 (16.3%) \cell +\pard\intbl\qc\fs18 47 (18.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Completed study \cell -\pard\intbl\qc\fs18 22 (26.2%) \cell \pard\intbl\qc\fs18 21 (25.0%) \cell +\pard\intbl\qc\fs18 22 (26.2%) \cell \pard\intbl\qc\fs18 48 (55.8%) \cell \pard\intbl\qc\fs18 91 (35.8%) \cell -\pard\intbl\qc\fs18 -29.6 (-43.7, -15.5) \cell -\pard\intbl\qc\fs18 -30.8 (-44.8, -16.8) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Discontinued study \cell -\pard\intbl\qc\fs18 44 (52.4%) \cell \pard\intbl\qc\fs18 48 (57.1%) \cell +\pard\intbl\qc\fs18 44 (52.4%) \cell \pard\intbl\qc\fs18 24 (27.9%) \cell \pard\intbl\qc\fs18 116 (45.7%) \cell -\pard\intbl\qc\fs18 24.5 (10.2, 38.8) \cell -\pard\intbl\qc\fs18 29.2 (15.0, 43.4) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4175 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5528 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6880 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8350 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10526 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lack of Efficacy \cell +\pard\intbl\qc\fs18 10 (11.9%) \cell +\pard\intbl\qc\fs18 9 (10.7%) \cell +\pard\intbl\qc\fs18 6 (7.0%) \cell +\pard\intbl\qc\fs18 25 (9.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Withdrawal by Subject \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 8 (9.5%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 15 (5.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pregnancy \cell +\pard\intbl\qc\fs18 6 (7.1%) \cell +\pard\intbl\qc\fs18 6 (7.1%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 15 (5.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Adverse Event \cell +\pard\intbl\qc\fs18 5 (6.0%) \cell +\pard\intbl\qc\fs18 4 (4.8%) \cell +\pard\intbl\qc\fs18 4 (4.7%) \cell +\pard\intbl\qc\fs18 13 (5.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Protocol Violation \cell +\pard\intbl\qc\fs18 9 (10.7%) \cell +\pard\intbl\qc\fs18 2 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 11 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Death \cell +\pard\intbl\qc\fs18 4 (4.8%) \cell +\pard\intbl\qc\fs18 4 (4.8%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 10 (3.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lost to Follow-up \cell +\pard\intbl\qc\fs18 3 (3.6%) \cell +\pard\intbl\qc\fs18 2 (2.4%) \cell +\pard\intbl\qc\fs18 5 (5.8%) \cell +\pard\intbl\qc\fs18 10 (3.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10070 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell -\pard\intbl\qc\fs18 44 (52.4%) \cell -\pard\intbl\qc\fs18 48 (57.1%) \cell -\pard\intbl\qc\fs18 24 (27.9%) \cell -\pard\intbl\qc\fs18 116 (45.7%) \cell -\pard\intbl\qc\fs18 24.5 (10.2, 38.8) \cell -\pard\intbl\qc\fs18 29.2 (15.0, 43.4) \cell +\pard\intbl\qc\fs18 6 (7.1%) \cell +\pard\intbl\qc\fs18 9 (10.7%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 17 (6.7%) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4175 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5528 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6880 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8350 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10526 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2861 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5264 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7667 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10070 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4175 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5528 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6880 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8350 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10526 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsids02a/tsids02a.rtf b/tests/testthat/_snaps/tsids02a/tsids02a.rtf deleted file mode 100755 index 04dc4d6c..00000000 --- a/tests/testthat/_snaps/tsids02a/tsids02a.rtf +++ /dev/null @@ -1,2686 +0,0 @@ -{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} - - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2857 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4254 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5652 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7050 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8447 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10574 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIDS02a:\tab Dummy Title\b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2857 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4254 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5652 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7050 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8447 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10574 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) 95% CI \cell -\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) 95% CI \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Total \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=84 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=84 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=86 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=254 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race: American Indian or Alaska Native \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 13 \cell -\pard\intbl\qc\fs18 6 \cell -\pard\intbl\qc\fs18 26 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Analysis set: \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Full \cell -\pard\intbl\qc\fs18 7 (100.0%) \cell -\pard\intbl\qc\fs18 13 (100.0%) \cell -\pard\intbl\qc\fs18 6 (100.0%) \cell -\pard\intbl\qc\fs18 26 (100.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Safety \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 10 (76.9%) \cell -\pard\intbl\qc\fs18 3 (50.0%) \cell -\pard\intbl\qc\fs18 18 (69.2%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Per protocol \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 10 (76.9%) \cell -\pard\intbl\qc\fs18 3 (50.0%) \cell -\pard\intbl\qc\fs18 18 (69.2%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects ongoing \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (7.7%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed treatment \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 3 (23.1%) \cell -\pard\intbl\qc\fs18 3 (50.0%) \cell -\pard\intbl\qc\fs18 7 (26.9%) \cell -\pard\intbl\qc\fs18 -35.7 (-83.4, 12.0) \cell -\pard\intbl\qc\fs18 -26.9 (-73.0, 19.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued treatment \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 7 (53.8%) \cell -\pard\intbl\qc\fs18 1 (16.7%) \cell -\pard\intbl\qc\fs18 13 (50.0%) \cell -\pard\intbl\qc\fs18 54.8 (9.9, 99.6) \cell -\pard\intbl\qc\fs18 37.2 (-3.1, 77.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 7 (53.8%) \cell -\pard\intbl\qc\fs18 1 (16.7%) \cell -\pard\intbl\qc\fs18 13 (50.0%) \cell -\pard\intbl\qc\fs18 54.8 (9.9, 99.6) \cell -\pard\intbl\qc\fs18 37.2 (-3.1, 77.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed study \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 3 (23.1%) \cell -\pard\intbl\qc\fs18 4 (66.7%) \cell -\pard\intbl\qc\fs18 9 (34.6%) \cell -\pard\intbl\qc\fs18 -38.1 (-88.5, 12.3) \cell -\pard\intbl\qc\fs18 -43.6 (-87.7, 0.5) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued study \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 10 (76.9%) \cell -\pard\intbl\qc\fs18 2 (33.3%) \cell -\pard\intbl\qc\fs18 15 (57.7%) \cell -\pard\intbl\qc\fs18 9.5 (-43.1, 62.1) \cell -\pard\intbl\qc\fs18 43.6 (-0.5, 87.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 10 (76.9%) \cell -\pard\intbl\qc\fs18 2 (33.3%) \cell -\pard\intbl\qc\fs18 15 (57.7%) \cell -\pard\intbl\qc\fs18 9.5 (-43.1, 62.1) \cell -\pard\intbl\qc\fs18 43.6 (-0.5, 87.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race: Asian \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Analysis set: \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Full \cell -\pard\intbl\qc\fs18 11 (100.0%) \cell -\pard\intbl\qc\fs18 11 (100.0%) \cell -\pard\intbl\qc\fs18 7 (100.0%) \cell -\pard\intbl\qc\fs18 29 (100.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Safety \cell -\pard\intbl\qc\fs18 11 (100.0%) \cell -\pard\intbl\qc\fs18 8 (72.7%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 24 (82.8%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Per protocol \cell -\pard\intbl\qc\fs18 11 (100.0%) \cell -\pard\intbl\qc\fs18 8 (72.7%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 24 (82.8%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects ongoing \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed treatment \cell -\pard\intbl\qc\fs18 3 (27.3%) \cell -\pard\intbl\qc\fs18 4 (36.4%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 9 (31.0%) \cell -\pard\intbl\qc\fs18 -1.3 (-43.9, 41.3) \cell -\pard\intbl\qc\fs18 7.8 (-36.1, 51.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued treatment \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 6 (54.5%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 16 (55.2%) \cell -\pard\intbl\qc\fs18 20.8 (-25.6, 67.2) \cell -\pard\intbl\qc\fs18 11.7 (-35.3, 58.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 6 (54.5%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 16 (55.2%) \cell -\pard\intbl\qc\fs18 20.8 (-25.6, 67.2) \cell -\pard\intbl\qc\fs18 11.7 (-35.3, 58.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed study \cell -\pard\intbl\qc\fs18 3 (27.3%) \cell -\pard\intbl\qc\fs18 3 (27.3%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 8 (27.6%) \cell -\pard\intbl\qc\fs18 -1.3 (-43.9, 41.3) \cell -\pard\intbl\qc\fs18 -1.3 (-43.9, 41.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued study \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 6 (54.5%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 16 (55.2%) \cell -\pard\intbl\qc\fs18 20.8 (-25.6, 67.2) \cell -\pard\intbl\qc\fs18 11.7 (-35.3, 58.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 6 (54.5%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 16 (55.2%) \cell -\pard\intbl\qc\fs18 20.8 (-25.6, 67.2) \cell -\pard\intbl\qc\fs18 11.7 (-35.3, 58.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race: Black or African American \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 10 \cell -\pard\intbl\qc\fs18 10 \cell -\pard\intbl\qc\fs18 27 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Analysis set: \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Full \cell -\pard\intbl\qc\fs18 7 (100.0%) \cell -\pard\intbl\qc\fs18 10 (100.0%) \cell -\pard\intbl\qc\fs18 10 (100.0%) \cell -\pard\intbl\qc\fs18 27 (100.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Safety \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 9 (90.0%) \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 21 (77.8%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Per protocol \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 9 (90.0%) \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 21 (77.8%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects ongoing \cell -\pard\intbl\qc\fs18 4 (57.1%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 7 (25.9%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed treatment \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 6 (60.0%) \cell -\pard\intbl\qc\fs18 10 (37.0%) \cell -\pard\intbl\qc\fs18 -31.4 (-76.6, 13.8) \cell -\pard\intbl\qc\fs18 -40.0 (-79.2, -0.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued treatment \cell -\pard\intbl\qc\fs18 4 (57.1%) \cell -\pard\intbl\qc\fs18 6 (60.0%) \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 13 (48.1%) \cell -\pard\intbl\qc\fs18 27.1 (-19.2, 73.5) \cell -\pard\intbl\qc\fs18 30.0 (-11.6, 71.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 4 (57.1%) \cell -\pard\intbl\qc\fs18 6 (60.0%) \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 13 (48.1%) \cell -\pard\intbl\qc\fs18 27.1 (-19.2, 73.5) \cell -\pard\intbl\qc\fs18 30.0 (-11.6, 71.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed study \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 8 (29.6%) \cell -\pard\intbl\qc\fs18 -1.4 (-45.3, 42.5) \cell -\pard\intbl\qc\fs18 0.0 (-40.2, 40.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued study \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 4 (40.0%) \cell -\pard\intbl\qc\fs18 12 (44.4%) \cell -\pard\intbl\qc\fs18 -25.7 (-65.6, 14.2) \cell -\pard\intbl\qc\fs18 30.0 (-11.6, 71.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 4 (40.0%) \cell -\pard\intbl\qc\fs18 12 (44.4%) \cell -\pard\intbl\qc\fs18 -25.7 (-65.6, 14.2) \cell -\pard\intbl\qc\fs18 30.0 (-11.6, 71.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race: Multiple \cell -\pard\intbl\qc\fs18 12 \cell -\pard\intbl\qc\fs18 9 \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Analysis set: \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Full \cell -\pard\intbl\qc\fs18 12 (100.0%) \cell -\pard\intbl\qc\fs18 9 (100.0%) \cell -\pard\intbl\qc\fs18 8 (100.0%) \cell -\pard\intbl\qc\fs18 29 (100.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Safety \cell -\pard\intbl\qc\fs18 11 (91.7%) \cell -\pard\intbl\qc\fs18 7 (77.8%) \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 23 (79.3%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Per protocol \cell -\pard\intbl\qc\fs18 11 (91.7%) \cell -\pard\intbl\qc\fs18 7 (77.8%) \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 23 (79.3%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects ongoing \cell -\pard\intbl\qc\fs18 2 (16.7%) \cell -\pard\intbl\qc\fs18 3 (33.3%) \cell -\pard\intbl\qc\fs18 1 (12.5%) \cell -\pard\intbl\qc\fs18 6 (20.7%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed treatment \cell -\pard\intbl\qc\fs18 2 (16.7%) \cell -\pard\intbl\qc\fs18 3 (33.3%) \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 9 (31.0%) \cell -\pard\intbl\qc\fs18 -33.3 (-73.9, 7.2) \cell -\pard\intbl\qc\fs18 -16.7 (-63.0, 29.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued treatment \cell -\pard\intbl\qc\fs18 7 (58.3%) \cell -\pard\intbl\qc\fs18 3 (33.3%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 12 (41.4%) \cell -\pard\intbl\qc\fs18 33.3 (-7.6, 74.3) \cell -\pard\intbl\qc\fs18 8.3 (-34.7, 51.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 7 (58.3%) \cell -\pard\intbl\qc\fs18 3 (33.3%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 12 (41.4%) \cell -\pard\intbl\qc\fs18 33.3 (-7.6, 74.3) \cell -\pard\intbl\qc\fs18 8.3 (-34.7, 51.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed study \cell -\pard\intbl\qc\fs18 4 (33.3%) \cell -\pard\intbl\qc\fs18 3 (33.3%) \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 11 (37.9%) \cell -\pard\intbl\qc\fs18 -16.7 (-60.4, 27.1) \cell -\pard\intbl\qc\fs18 -16.7 (-63.0, 29.7) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued study \cell -\pard\intbl\qc\fs18 6 (50.0%) \cell -\pard\intbl\qc\fs18 3 (33.3%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 12 (41.4%) \cell -\pard\intbl\qc\fs18 12.5 (-31.4, 56.4) \cell -\pard\intbl\qc\fs18 -4.2 (-49.7, 41.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 6 (50.0%) \cell -\pard\intbl\qc\fs18 3 (33.3%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 12 (41.4%) \cell -\pard\intbl\qc\fs18 12.5 (-31.4, 56.4) \cell -\pard\intbl\qc\fs18 -4.2 (-49.7, 41.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race: Native Hawaiian or other Pacific Islander \cell -\pard\intbl\qc\fs18 10 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 8 \cell -\pard\intbl\qc\fs18 25 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Analysis set: \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Full \cell -\pard\intbl\qc\fs18 10 (100.0%) \cell -\pard\intbl\qc\fs18 7 (100.0%) \cell -\pard\intbl\qc\fs18 8 (100.0%) \cell -\pard\intbl\qc\fs18 25 (100.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Safety \cell -\pard\intbl\qc\fs18 8 (80.0%) \cell -\pard\intbl\qc\fs18 4 (57.1%) \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 17 (68.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Per protocol \cell -\pard\intbl\qc\fs18 8 (80.0%) \cell -\pard\intbl\qc\fs18 4 (57.1%) \cell -\pard\intbl\qc\fs18 5 (62.5%) \cell -\pard\intbl\qc\fs18 17 (68.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects ongoing \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 6 (24.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed treatment \cell -\pard\intbl\qc\fs18 1 (10.0%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 4 (50.0%) \cell -\pard\intbl\qc\fs18 6 (24.0%) \cell -\pard\intbl\qc\fs18 -40.0 (-79.3, -0.7) \cell -\pard\intbl\qc\fs18 -35.7 (-79.0, 7.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued treatment \cell -\pard\intbl\qc\fs18 6 (60.0%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 14 (56.0%) \cell -\pard\intbl\qc\fs18 22.5 (-22.7, 67.7) \cell -\pard\intbl\qc\fs18 33.9 (-13.5, 81.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 6 (60.0%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 14 (56.0%) \cell -\pard\intbl\qc\fs18 22.5 (-22.7, 67.7) \cell -\pard\intbl\qc\fs18 33.9 (-13.5, 81.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed study \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 6 (24.0%) \cell -\pard\intbl\qc\fs18 -17.5 (-59.2, 24.2) \cell -\pard\intbl\qc\fs18 -23.2 (-65.6, 19.2) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued study \cell -\pard\intbl\qc\fs18 5 (50.0%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 13 (52.0%) \cell -\pard\intbl\qc\fs18 12.5 (-33.2, 58.2) \cell -\pard\intbl\qc\fs18 33.9 (-13.5, 81.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 5 (50.0%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 13 (52.0%) \cell -\pard\intbl\qc\fs18 12.5 (-33.2, 58.2) \cell -\pard\intbl\qc\fs18 33.9 (-13.5, 81.3) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race: Not reported \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 7 \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 29 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Analysis set: \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Full \cell -\pard\intbl\qc\fs18 11 (100.0%) \cell -\pard\intbl\qc\fs18 7 (100.0%) \cell -\pard\intbl\qc\fs18 11 (100.0%) \cell -\pard\intbl\qc\fs18 29 (100.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Safety \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 9 (81.8%) \cell -\pard\intbl\qc\fs18 21 (72.4%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Per protocol \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 5 (71.4%) \cell -\pard\intbl\qc\fs18 9 (81.8%) \cell -\pard\intbl\qc\fs18 21 (72.4%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects ongoing \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 5 (17.2%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed treatment \cell -\pard\intbl\qc\fs18 3 (27.3%) \cell -\pard\intbl\qc\fs18 1 (14.3%) \cell -\pard\intbl\qc\fs18 6 (54.5%) \cell -\pard\intbl\qc\fs18 10 (34.5%) \cell -\pard\intbl\qc\fs18 -27.3 (-66.8, 12.2) \cell -\pard\intbl\qc\fs18 -40.3 (-79.5, -1.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued treatment \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 12 (41.4%) \cell -\pard\intbl\qc\fs18 45.5 (9.0, 81.9) \cell -\pard\intbl\qc\fs18 24.7 (-18.5, 67.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 3 (42.9%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 12 (41.4%) \cell -\pard\intbl\qc\fs18 45.5 (9.0, 81.9) \cell -\pard\intbl\qc\fs18 24.7 (-18.5, 67.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed study \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 2 (28.6%) \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 11 (37.9%) \cell -\pard\intbl\qc\fs18 -45.5 (-81.9, -9.0) \cell -\pard\intbl\qc\fs18 -35.1 (-79.0, 8.8) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued study \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 4 (57.1%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 13 (44.8%) \cell -\pard\intbl\qc\fs18 45.5 (9.0, 81.9) \cell -\pard\intbl\qc\fs18 39.0 (-4.2, 82.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 7 (63.6%) \cell -\pard\intbl\qc\fs18 4 (57.1%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 13 (44.8%) \cell -\pard\intbl\qc\fs18 45.5 (9.0, 81.9) \cell -\pard\intbl\qc\fs18 39.0 (-4.2, 82.1) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race: Other \cell -\pard\intbl\qc\fs18 5 \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 16 \cell -\pard\intbl\qc\fs18 32 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Analysis set: \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Full \cell -\pard\intbl\qc\fs18 5 (100.0%) \cell -\pard\intbl\qc\fs18 11 (100.0%) \cell -\pard\intbl\qc\fs18 16 (100.0%) \cell -\pard\intbl\qc\fs18 32 (100.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Safety \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 8 (72.7%) \cell -\pard\intbl\qc\fs18 10 (62.5%) \cell -\pard\intbl\qc\fs18 19 (59.4%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Per protocol \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 8 (72.7%) \cell -\pard\intbl\qc\fs18 10 (62.5%) \cell -\pard\intbl\qc\fs18 19 (59.4%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects ongoing \cell -\pard\intbl\qc\fs18 1 (20.0%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 1 (6.2%) \cell -\pard\intbl\qc\fs18 4 (12.5%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed treatment \cell -\pard\intbl\qc\fs18 3 (60.0%) \cell -\pard\intbl\qc\fs18 4 (36.4%) \cell -\pard\intbl\qc\fs18 8 (50.0%) \cell -\pard\intbl\qc\fs18 15 (46.9%) \cell -\pard\intbl\qc\fs18 10.0 (-39.4, 59.4) \cell -\pard\intbl\qc\fs18 -13.6 (-51.2, 23.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued treatment \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 5 (45.5%) \cell -\pard\intbl\qc\fs18 5 (31.2%) \cell -\pard\intbl\qc\fs18 12 (37.5%) \cell -\pard\intbl\qc\fs18 8.8 (-39.8, 57.3) \cell -\pard\intbl\qc\fs18 14.2 (-23.0, 51.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 5 (45.5%) \cell -\pard\intbl\qc\fs18 5 (31.2%) \cell -\pard\intbl\qc\fs18 12 (37.5%) \cell -\pard\intbl\qc\fs18 8.8 (-39.8, 57.3) \cell -\pard\intbl\qc\fs18 14.2 (-23.0, 51.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed study \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 4 (36.4%) \cell -\pard\intbl\qc\fs18 10 (62.5%) \cell -\pard\intbl\qc\fs18 16 (50.0%) \cell -\pard\intbl\qc\fs18 -22.5 (-71.6, 26.6) \cell -\pard\intbl\qc\fs18 -26.1 (-63.2, 10.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued study \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 5 (45.5%) \cell -\pard\intbl\qc\fs18 5 (31.2%) \cell -\pard\intbl\qc\fs18 12 (37.5%) \cell -\pard\intbl\qc\fs18 8.8 (-39.8, 57.3) \cell -\pard\intbl\qc\fs18 14.2 (-23.0, 51.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 2 (40.0%) \cell -\pard\intbl\qc\fs18 5 (45.5%) \cell -\pard\intbl\qc\fs18 5 (31.2%) \cell -\pard\intbl\qc\fs18 12 (37.5%) \cell -\pard\intbl\qc\fs18 8.8 (-39.8, 57.3) \cell -\pard\intbl\qc\fs18 14.2 (-23.0, 51.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race: Unknown \cell -\pard\intbl\qc\fs18 10 \cell -\pard\intbl\qc\fs18 6 \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 27 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Analysis set: \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Full \cell -\pard\intbl\qc\fs18 10 (100.0%) \cell -\pard\intbl\qc\fs18 6 (100.0%) \cell -\pard\intbl\qc\fs18 11 (100.0%) \cell -\pard\intbl\qc\fs18 27 (100.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Safety \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 4 (66.7%) \cell -\pard\intbl\qc\fs18 8 (72.7%) \cell -\pard\intbl\qc\fs18 19 (70.4%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Per protocol \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 4 (66.7%) \cell -\pard\intbl\qc\fs18 8 (72.7%) \cell -\pard\intbl\qc\fs18 19 (70.4%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects ongoing \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (50.0%) \cell -\pard\intbl\qc\fs18 1 (9.1%) \cell -\pard\intbl\qc\fs18 4 (14.8%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed treatment \cell -\pard\intbl\qc\fs18 2 (20.0%) \cell -\pard\intbl\qc\fs18 2 (33.3%) \cell -\pard\intbl\qc\fs18 9 (81.8%) \cell -\pard\intbl\qc\fs18 13 (48.1%) \cell -\pard\intbl\qc\fs18 -61.8 (-95.5, -28.1) \cell -\pard\intbl\qc\fs18 -48.5 (-92.6, -4.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued treatment \cell -\pard\intbl\qc\fs18 6 (60.0%) \cell -\pard\intbl\qc\fs18 1 (16.7%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 9 (33.3%) \cell -\pard\intbl\qc\fs18 41.8 (3.9, 79.8) \cell -\pard\intbl\qc\fs18 -1.5 (-39.0, 36.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 6 (60.0%) \cell -\pard\intbl\qc\fs18 1 (16.7%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 9 (33.3%) \cell -\pard\intbl\qc\fs18 41.8 (3.9, 79.8) \cell -\pard\intbl\qc\fs18 -1.5 (-39.0, 36.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed study \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 2 (33.3%) \cell -\pard\intbl\qc\fs18 8 (72.7%) \cell -\pard\intbl\qc\fs18 13 (48.1%) \cell -\pard\intbl\qc\fs18 -42.7 (-81.4, -4.0) \cell -\pard\intbl\qc\fs18 -39.4 (-85.4, 6.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued study \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 1 (16.7%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 10 (37.0%) \cell -\pard\intbl\qc\fs18 51.8 (15.4, 88.2) \cell -\pard\intbl\qc\fs18 -1.5 (-39.0, 36.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 1 (16.7%) \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 10 (37.0%) \cell -\pard\intbl\qc\fs18 51.8 (15.4, 88.2) \cell -\pard\intbl\qc\fs18 -1.5 (-39.0, 36.0) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Race: White \cell -\pard\intbl\qc\fs18 11 \cell -\pard\intbl\qc\fs18 10 \cell -\pard\intbl\qc\fs18 9 \cell -\pard\intbl\qc\fs18 30 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Analysis set: \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Full \cell -\pard\intbl\qc\fs18 11 (100.0%) \cell -\pard\intbl\qc\fs18 10 (100.0%) \cell -\pard\intbl\qc\fs18 9 (100.0%) \cell -\pard\intbl\qc\fs18 30 (100.0%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Safety \cell -\pard\intbl\qc\fs18 9 (81.8%) \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 7 (77.8%) \cell -\pard\intbl\qc\fs18 23 (76.7%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Per protocol \cell -\pard\intbl\qc\fs18 9 (81.8%) \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 7 (77.8%) \cell -\pard\intbl\qc\fs18 23 (76.7%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Subjects ongoing \cell -\pard\intbl\qc\fs18 3 (27.3%) \cell -\pard\intbl\qc\fs18 3 (30.0%) \cell -\pard\intbl\qc\fs18 2 (22.2%) \cell -\pard\intbl\qc\fs18 8 (26.7%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed treatment \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 1 (10.0%) \cell -\pard\intbl\qc\fs18 7 (77.8%) \cell -\pard\intbl\qc\fs18 10 (33.3%) \cell -\pard\intbl\qc\fs18 -59.6 (-95.1, -24.1) \cell -\pard\intbl\qc\fs18 -67.8 (-100.0, -34.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued treatment \cell -\pard\intbl\qc\fs18 5 (45.5%) \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 13 (43.3%) \cell -\pard\intbl\qc\fs18 34.3 (-1.5, 70.2) \cell -\pard\intbl\qc\fs18 58.9 (23.8, 93.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 5 (45.5%) \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 1 (11.1%) \cell -\pard\intbl\qc\fs18 13 (43.3%) \cell -\pard\intbl\qc\fs18 34.3 (-1.5, 70.2) \cell -\pard\intbl\qc\fs18 58.9 (23.8, 93.9) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Completed study \cell -\pard\intbl\qc\fs18 2 (18.2%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 7 (77.8%) \cell -\pard\intbl\qc\fs18 9 (30.0%) \cell -\pard\intbl\qc\fs18 -59.6 (-95.1, -24.1) \cell -\pard\intbl\qc\fs18 -77.8 (-100.0, -50.6) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Discontinued study \cell -\pard\intbl\qc\fs18 6 (54.5%) \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 13 (43.3%) \cell -\pard\intbl\qc\fs18 54.5 (25.1, 84.0) \cell -\pard\intbl\qc\fs18 70.0 (41.6, 98.4) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2857 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4254 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5652 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7050 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8447 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10574 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell -\pard\intbl\qc\fs18 6 (54.5%) \cell -\pard\intbl\qc\fs18 7 (70.0%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 13 (43.3%) \cell -\pard\intbl\qc\fs18 54.5 (25.1, 84.0) \cell -\pard\intbl\qc\fs18 70.0 (41.6, 98.4) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2857 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4254 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5652 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7050 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8447 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10574 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2857 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4254 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5652 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7050 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8447 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10574 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\row -} - -} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsids02b/tsids02b.rtf b/tests/testthat/_snaps/tsids02b/tsids02b.rtf new file mode 100644 index 00000000..79d377f9 --- /dev/null +++ b/tests/testthat/_snaps/tsids02b/tsids02b.rtf @@ -0,0 +1,564 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2861 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5264 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7667 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10070 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIDS02b:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2861 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5264 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7667 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10070 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Total \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=182 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects ongoing any treatment \cell +\pard\intbl\qc\fs18 24 (40.7%) \cell +\pard\intbl\qc\fs18 32 (54.2%) \cell +\pard\intbl\qc\fs18 37 (57.8%) \cell +\pard\intbl\qc\fs18 93 (51.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Completed treatment\super a\nosupersub \cell +\pard\intbl\qc\fs18 12 (20.3%) \cell +\pard\intbl\qc\fs18 8 (13.6%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 24 (13.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Discontinued both study agents \cell +\pard\intbl\qc\fs18 5 (8.5%) \cell +\pard\intbl\qc\fs18 5 (8.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Discontinued one study agent \cell +\pard\intbl\qc\fs18 32 (54.2%) \cell +\pard\intbl\qc\fs18 33 (55.9%) \cell +\pard\intbl\qc\fs18 38 (59.4%) \cell +\pard\intbl\qc\fs18 103 (56.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Completed treatment with study agent 1 \cell +\pard\intbl\qc\fs18 27 (45.8%) \cell +\pard\intbl\qc\fs18 25 (42.4%) \cell +\pard\intbl\qc\fs18 24 (37.5%) \cell +\pard\intbl\qc\fs18 76 (41.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Discontinued treatment with study agent 1 \cell +\pard\intbl\qc\fs18 17 (28.8%) \cell +\pard\intbl\qc\fs18 17 (28.8%) \cell +\pard\intbl\qc\fs18 19 (29.7%) \cell +\pard\intbl\qc\fs18 53 (29.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Death \cell +\pard\intbl\qc\fs18 4 (6.8%) \cell +\pard\intbl\qc\fs18 5 (8.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lack of Efficacy \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 3 (5.1%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 9 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Withdrawal by Subject \cell +\pard\intbl\qc\fs18 4 (6.8%) \cell +\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 9 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Protocol Violation \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 6 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Adverse Event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (6.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 5 (2.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell +\pard\intbl\qc\fs18 5 (8.5%) \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 11 (6.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Completed treatment with study agent 2 \cell +\pard\intbl\qc\fs18 27 (45.8%) \cell +\pard\intbl\qc\fs18 16 (27.1%) \cell +\pard\intbl\qc\fs18 21 (32.8%) \cell +\pard\intbl\qc\fs18 64 (35.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Discontinued treatment with study agent 2 \cell +\pard\intbl\qc\fs18 20 (33.9%) \cell +\pard\intbl\qc\fs18 21 (35.6%) \cell +\pard\intbl\qc\fs18 22 (34.4%) \cell +\pard\intbl\qc\fs18 63 (34.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Adverse Event \cell +\pard\intbl\qc\fs18 7 (11.9%) \cell +\pard\intbl\qc\fs18 5 (8.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 18 (9.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Death \cell +\pard\intbl\qc\fs18 7 (11.9%) \cell +\pard\intbl\qc\fs18 4 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 13 (7.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Protocol Violation \cell +\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 5 (8.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 12 (6.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lack of Efficacy \cell +\pard\intbl\qc\fs18 3 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 7 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Withdrawal by Subject \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 3 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 3 (5.1%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\pard\intbl\qc\fs18 10 (5.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects ongoing study \cell +\pard\intbl\qc\fs18 11 (18.6%) \cell +\pard\intbl\qc\fs18 12 (20.3%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\pard\intbl\qc\fs18 34 (18.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Completed study \cell +\pard\intbl\qc\fs18 16 (27.1%) \cell +\pard\intbl\qc\fs18 16 (27.1%) \cell +\pard\intbl\qc\fs18 33 (51.6%) \cell +\pard\intbl\qc\fs18 65 (35.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Discontinued study \cell +\pard\intbl\qc\fs18 32 (54.2%) \cell +\pard\intbl\qc\fs18 31 (52.5%) \cell +\pard\intbl\qc\fs18 20 (31.3%) \cell +\pard\intbl\qc\fs18 83 (45.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lack of Efficacy \cell +\pard\intbl\qc\fs18 9 (15.3%) \cell +\pard\intbl\qc\fs18 5 (8.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\pard\intbl\qc\fs18 20 (11.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Adverse Event \cell +\pard\intbl\qc\fs18 3 (5.1%) \cell +\pard\intbl\qc\fs18 4 (6.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\pard\intbl\qc\fs18 11 (6.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pregnancy \cell +\pard\intbl\qc\fs18 3 (5.1%) \cell +\pard\intbl\qc\fs18 5 (8.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 10 (5.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Withdrawal by Subject \cell +\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 6 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\pard\intbl\qc\fs18 8 (4.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Death \cell +\pard\intbl\qc\fs18 4 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 8 (4.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Protocol Violation \cell +\pard\intbl\qc\fs18 6 (10.2%) \cell +\pard\intbl\qc\fs18 1 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lost to Follow-up \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.4%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\pard\intbl\qc\fs18 7 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2861 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5264 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7667 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10070 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (6.8%) \cell +\pard\intbl\qc\fs18 6 (10.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\pard\intbl\qc\fs18 12 (6.6%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2861 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5264 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7667 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10070 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2861 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5264 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7667 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10070 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsiex01/tsiex01.rtf b/tests/testthat/_snaps/tsiex01/tsiex01.rtf old mode 100755 new mode 100644 index 6d485a5b..48453a17 --- a/tests/testthat/_snaps/tsiex01/tsiex01.rtf +++ b/tests/testthat/_snaps/tsiex01/tsiex01.rtf @@ -3,89 +3,97 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4347 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5871 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7395 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8919 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10895 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5299 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7766 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10234 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX01:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4347 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5871 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7395 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8919 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10895 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2831 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5299 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7766 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10234 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Means (95% CI) \cell -\pard\intbl\qc\fs18 \keepn\trhdr Difference in Means (95% CI) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10895 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Duration of treatment\super a\nosupersub , ([unit]) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subgroup: \u8805?18 to <65 \cell +\pard\intbl\qc\fs18 4 \cell +\pard\intbl\qc\fs18 9 \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 12 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Duration of treatment\super a\nosupersub , (months) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -93,123 +101,95 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 17.41 (11.408) \cell -\pard\intbl\qc\fs18 20.46 (10.198) \cell -\pard\intbl\qc\fs18 19.18 (10.786) \cell -\pard\intbl\qc\fs18 18.64 (10.656) \cell -\pard\intbl\qc\fs18 -1.23 (-5.23, 2.77) \cell -\pard\intbl\qc\fs18 1.82 (-1.88, 5.52) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 16.63 (8.506) \cell +\pard\intbl\qc\fs18 17.99 (10.503) \cell +\pard\intbl\qc\fs18 17.57 (9.595) \cell +\pard\intbl\qc\fs18 17.82 (10.272) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Median \cell -\pard\intbl\qc\fs18 16.10 \cell -\pard\intbl\qc\fs18 21.20 \cell -\pard\intbl\qc\fs18 18.90 \cell -\pard\intbl\qc\fs18 18.60 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 14.55 \cell +\pard\intbl\qc\fs18 18.70 \cell +\pard\intbl\qc\fs18 18.70 \cell +\pard\intbl\qc\fs18 19.45 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0.2, 35.4 \cell -\pard\intbl\qc\fs18 0.1, 37.9 \cell -\pard\intbl\qc\fs18 0.1, 37.9 \cell -\pard\intbl\qc\fs18 0.9, 37.2 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 9.8, 27.6 \cell +\pard\intbl\qc\fs18 1.1, 33.0 \cell +\pard\intbl\qc\fs18 1.1, 33.0 \cell +\pard\intbl\qc\fs18 6.4, 35.4 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 8.30, 27.80 \cell -\pard\intbl\qc\fs18 14.70, 28.10 \cell -\pard\intbl\qc\fs18 11.30, 28.00 \cell -\pard\intbl\qc\fs18 9.30, 26.30 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 9.90, 23.35 \cell +\pard\intbl\qc\fs18 12.60, 23.60 \cell +\pard\intbl\qc\fs18 10.00, 23.60 \cell +\pard\intbl\qc\fs18 7.80, 24.85 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total treatment (subject years) \cell -\pard\intbl\qc\fs18 922.9 (76.9) \cell -\pard\intbl\qc\fs18 1493.8 (124.5) \cell -\pard\intbl\qc\fs18 2416.7 (201.4) \cell -\pard\intbl\qc\fs18 1099.9 (91.7) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total treatment (subject years) \cell +\pard\intbl\qc\fs18 5.54166666666667 \cell +\pard\intbl\qc\fs18 13.4916666666667 \cell +\pard\intbl\qc\fs18 19.0333333333333 \cell +\pard\intbl\qc\fs18 17.8166666666667 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Duration of treatment, n (%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Duration of treatment, n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -219,71 +199,195 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 0 to <3 months \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 11 (8.7%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 0 to <3 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 3 to <6 months \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 5 (6.8%) \cell -\pard\intbl\qc\fs18 10 (7.9%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 3 to <6 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 6 to <9 months \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 6 to <9 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 5 (41.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 9 to <12 months \cell +\pard\intbl\qc\fs18 2 (50.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (15.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 12 to <15 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 15 to <18 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 18 to <21 months \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell +\pard\intbl\qc\fs18 3 (23.1%) \cell +\pard\intbl\qc\fs18 3 (25.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 21 to <24 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 24 to <27 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 27 to <30 months \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 30 to <33 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 9 to <12 months \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 6 (4.8%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 33 to <36 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (11.1%) \cell +\pard\intbl\qc\fs18 1 (7.7%) \cell +\pard\intbl\qc\fs18 1 (8.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 36 to <39 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -291,35 +395,125 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 12 to <15 months \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Duration of treatment\super b\nosupersub , n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <1 month \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?1 month \cell +\pard\intbl\qc\fs18 4 (100.0%) \cell +\pard\intbl\qc\fs18 9 (100.0%) \cell +\pard\intbl\qc\fs18 13 (100.0%) \cell +\pard\intbl\qc\fs18 12 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?2 months \cell +\pard\intbl\qc\fs18 4 (100.0%) \cell +\pard\intbl\qc\fs18 8 (88.9%) \cell +\pard\intbl\qc\fs18 12 (92.3%) \cell +\pard\intbl\qc\fs18 12 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?3 months \cell +\pard\intbl\qc\fs18 4 (100.0%) \cell +\pard\intbl\qc\fs18 8 (88.9%) \cell +\pard\intbl\qc\fs18 12 (92.3%) \cell +\pard\intbl\qc\fs18 12 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?6 months \cell +\pard\intbl\qc\fs18 4 (100.0%) \cell +\pard\intbl\qc\fs18 8 (88.9%) \cell +\pard\intbl\qc\fs18 12 (92.3%) \cell +\pard\intbl\qc\fs18 12 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?12 months \cell +\pard\intbl\qc\fs18 2 (50.0%) \cell +\pard\intbl\qc\fs18 7 (77.8%) \cell +\pard\intbl\qc\fs18 9 (69.2%) \cell +\pard\intbl\qc\fs18 7 (58.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 15 to <18 months \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 10 (13.7%) \cell -\pard\intbl\qc\fs18 13 (10.3%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?24 months \cell +\pard\intbl\qc\fs18 1 (25.0%) \cell +\pard\intbl\qc\fs18 2 (22.2%) \cell +\pard\intbl\qc\fs18 3 (23.1%) \cell +\pard\intbl\qc\fs18 3 (25.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -327,17 +521,27 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 18 to <21 months \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subgroup: \u8805?65 to <75 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 16 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -345,17 +549,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 21 to <24 months \cell -\pard\intbl\qc\fs18 1 (1.9%) \cell -\pard\intbl\qc\fs18 7 (9.6%) \cell -\pard\intbl\qc\fs18 8 (6.3%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Duration of treatment\super a\nosupersub , (months) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -363,17 +563,83 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 24 to <27 months \cell -\pard\intbl\qc\fs18 3 (5.7%) \cell -\pard\intbl\qc\fs18 6 (8.2%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 6 (10.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 18.52 (10.640) \cell +\pard\intbl\qc\fs18 19.13 (10.400) \cell +\pard\intbl\qc\fs18 18.79 (10.379) \cell +\pard\intbl\qc\fs18 15.52 (8.317) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 14.30 \cell +\pard\intbl\qc\fs18 18.80 \cell +\pard\intbl\qc\fs18 17.10 \cell +\pard\intbl\qc\fs18 12.80 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 1.2, 34.0 \cell +\pard\intbl\qc\fs18 0.3, 34.0 \cell +\pard\intbl\qc\fs18 0.3, 34.0 \cell +\pard\intbl\qc\fs18 4.6, 32.9 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 9.00, 28.60 \cell +\pard\intbl\qc\fs18 12.00, 30.50 \cell +\pard\intbl\qc\fs18 9.80, 28.60 \cell +\pard\intbl\qc\fs18 9.95, 22.10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total treatment (subject years) \cell +\pard\intbl\qc\fs18 29.3166666666667 \cell +\pard\intbl\qc\fs18 23.9083333333333 \cell +\pard\intbl\qc\fs18 53.225 \cell +\pard\intbl\qc\fs18 20.6916666666667 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -381,35 +647,209 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 27 to <30 months \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 15 (11.9%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Duration of treatment, n (%) \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 0 to <3 months \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 3 to <6 months \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 6 to <9 months \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (13.3%) \cell +\pard\intbl\qc\fs18 4 (11.8%) \cell +\pard\intbl\qc\fs18 2 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 9 to <12 months \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 4 (25.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 12 to <15 months \cell +\pard\intbl\qc\fs18 4 (21.1%) \cell +\pard\intbl\qc\fs18 2 (13.3%) \cell +\pard\intbl\qc\fs18 6 (17.6%) \cell +\pard\intbl\qc\fs18 3 (18.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 15 to <18 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (13.3%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 18 to <21 months \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (13.3%) \cell +\pard\intbl\qc\fs18 3 (8.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 21 to <24 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 3 (18.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 24 to <27 months \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (8.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 27 to <30 months \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 2 (5.9%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 30 to <33 months \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 3 (20.0%) \cell +\pard\intbl\qc\fs18 5 (14.7%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 33 to <36 months \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 3 (8.8%) \cell +\pard\intbl\qc\fs18 0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 30 to <33 months \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 4 (5.5%) \cell -\pard\intbl\qc\fs18 9 (7.1%) \cell -\pard\intbl\qc\fs18 3 (5.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 36 to <39 months \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -417,17 +857,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 33 to <36 months \cell -\pard\intbl\qc\fs18 5 (9.4%) \cell -\pard\intbl\qc\fs18 9 (12.3%) \cell -\pard\intbl\qc\fs18 14 (11.1%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Duration of treatment\super b\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -435,17 +871,111 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 36 to <39 months \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <1 month \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.7%) \cell -\pard\intbl\qc\fs18 2 (1.6%) \cell -\pard\intbl\qc\fs18 4 (6.8%) \cell +\pard\intbl\qc\fs18 1 (6.7%) \cell +\pard\intbl\qc\fs18 1 (2.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?1 month \cell +\pard\intbl\qc\fs18 19 (100.0%) \cell +\pard\intbl\qc\fs18 14 (93.3%) \cell +\pard\intbl\qc\fs18 33 (97.1%) \cell +\pard\intbl\qc\fs18 16 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?2 months \cell +\pard\intbl\qc\fs18 18 (94.7%) \cell +\pard\intbl\qc\fs18 14 (93.3%) \cell +\pard\intbl\qc\fs18 32 (94.1%) \cell +\pard\intbl\qc\fs18 16 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?3 months \cell +\pard\intbl\qc\fs18 18 (94.7%) \cell +\pard\intbl\qc\fs18 14 (93.3%) \cell +\pard\intbl\qc\fs18 32 (94.1%) \cell +\pard\intbl\qc\fs18 16 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?6 months \cell +\pard\intbl\qc\fs18 17 (89.5%) \cell +\pard\intbl\qc\fs18 14 (93.3%) \cell +\pard\intbl\qc\fs18 31 (91.2%) \cell +\pard\intbl\qc\fs18 15 (93.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?12 months \cell +\pard\intbl\qc\fs18 13 (68.4%) \cell +\pard\intbl\qc\fs18 12 (80.0%) \cell +\pard\intbl\qc\fs18 25 (73.5%) \cell +\pard\intbl\qc\fs18 9 (56.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?24 months \cell +\pard\intbl\qc\fs18 8 (42.1%) \cell +\pard\intbl\qc\fs18 5 (33.3%) \cell +\pard\intbl\qc\fs18 13 (38.2%) \cell +\pard\intbl\qc\fs18 2 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -453,17 +983,41 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subgroup: \u8805?75 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 71 \cell +\pard\intbl\qc\fs18 36 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Duration of treatment\super a\nosupersub , (months) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -471,125 +1025,293 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Duration of treatment\super b\nosupersub , n (%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 18.57 (9.468) \cell +\pard\intbl\qc\fs18 14.88 (12.122) \cell +\pard\intbl\qc\fs18 17.17 (10.625) \cell +\pard\intbl\qc\fs18 18.57 (11.165) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 19.60 \cell +\pard\intbl\qc\fs18 10.00 \cell +\pard\intbl\qc\fs18 17.20 \cell +\pard\intbl\qc\fs18 17.55 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 1.5, 36.7 \cell +\pard\intbl\qc\fs18 1.3, 37.5 \cell +\pard\intbl\qc\fs18 1.3, 37.5 \cell +\pard\intbl\qc\fs18 1.1, 36.7 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 10.20, 25.80 \cell +\pard\intbl\qc\fs18 4.20, 21.60 \cell +\pard\intbl\qc\fs18 6.70, 25.70 \cell +\pard\intbl\qc\fs18 7.60, 27.95 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total treatment (subject years) \cell +\pard\intbl\qc\fs18 68.0833333333333 \cell +\pard\intbl\qc\fs18 33.4833333333333 \cell +\pard\intbl\qc\fs18 101.566666666667 \cell +\pard\intbl\qc\fs18 55.7166666666667 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Duration of treatment, n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 0 to <3 months \cell +\pard\intbl\qc\fs18 3 (6.8%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 6 (8.5%) \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 3 to <6 months \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 6 (22.2%) \cell +\pard\intbl\qc\fs18 8 (11.3%) \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 6 to <9 months \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 4 (14.8%) \cell +\pard\intbl\qc\fs18 6 (8.5%) \cell +\pard\intbl\qc\fs18 6 (16.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 9 to <12 months \cell +\pard\intbl\qc\fs18 7 (15.9%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 8 (11.3%) \cell +\pard\intbl\qc\fs18 3 (8.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 <1 month \cell -\pard\intbl\qc\fs18 4 (7.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 12 to <15 months \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (1.4%) \cell -\pard\intbl\qc\fs18 5 (4.0%) \cell -\pard\intbl\qc\fs18 1 (1.7%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?1 month \cell -\pard\intbl\qc\fs18 49 (92.5%) \cell -\pard\intbl\qc\fs18 72 (98.6%) \cell -\pard\intbl\qc\fs18 121 (96.0%) \cell -\pard\intbl\qc\fs18 58 (98.3%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 15 to <18 months \cell +\pard\intbl\qc\fs18 5 (11.4%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 8 (11.3%) \cell +\pard\intbl\qc\fs18 3 (8.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 months \cell -\pard\intbl\qc\fs18 46 (86.8%) \cell -\pard\intbl\qc\fs18 71 (97.3%) \cell -\pard\intbl\qc\fs18 117 (92.9%) \cell -\pard\intbl\qc\fs18 58 (98.3%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 18 to <21 months \cell +\pard\intbl\qc\fs18 7 (15.9%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 8 (11.3%) \cell +\pard\intbl\qc\fs18 4 (11.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?3 months \cell -\pard\intbl\qc\fs18 46 (86.8%) \cell -\pard\intbl\qc\fs18 69 (94.5%) \cell -\pard\intbl\qc\fs18 115 (91.3%) \cell -\pard\intbl\qc\fs18 57 (96.6%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 21 to <24 months \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 3 (11.1%) \cell +\pard\intbl\qc\fs18 5 (7.0%) \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?6 months \cell -\pard\intbl\qc\fs18 41 (77.4%) \cell -\pard\intbl\qc\fs18 64 (87.7%) \cell -\pard\intbl\qc\fs18 105 (83.3%) \cell -\pard\intbl\qc\fs18 52 (88.1%) \cell -\pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 24 to <27 months \cell +\pard\intbl\qc\fs18 7 (15.9%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 8 (11.3%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 27 to <30 months \cell +\pard\intbl\qc\fs18 2 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 4 (11.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 30 to <33 months \cell +\pard\intbl\qc\fs18 4 (9.1%) \cell +\pard\intbl\qc\fs18 1 (3.7%) \cell +\pard\intbl\qc\fs18 5 (7.0%) \cell +\pard\intbl\qc\fs18 1 (2.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?12 months \cell -\pard\intbl\qc\fs18 34 (64.2%) \cell -\pard\intbl\qc\fs18 59 (80.8%) \cell -\pard\intbl\qc\fs18 93 (73.8%) \cell -\pard\intbl\qc\fs18 38 (64.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 33 to <36 months \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 4 (11.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 36 to <39 months \cell +\pard\intbl\qc\fs18 1 (2.3%) \cell +\pard\intbl\qc\fs18 2 (7.4%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 2 (5.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -597,17 +1319,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4347 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5871 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7395 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8919 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10895 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?24 months \cell -\pard\intbl\qc\fs18 19 (35.8%) \cell -\pard\intbl\qc\fs18 30 (41.1%) \cell -\pard\intbl\qc\fs18 49 (38.9%) \cell -\pard\intbl\qc\fs18 20 (33.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Duration of treatment\super b\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row @@ -615,37 +1333,127 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4347 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5871 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7395 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8919 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10895 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <1 month \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?1 month \cell +\pard\intbl\qc\fs18 44 (100.0%) \cell +\pard\intbl\qc\fs18 27 (100.0%) \cell +\pard\intbl\qc\fs18 71 (100.0%) \cell +\pard\intbl\qc\fs18 36 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?2 months \cell +\pard\intbl\qc\fs18 43 (97.7%) \cell +\pard\intbl\qc\fs18 25 (92.6%) \cell +\pard\intbl\qc\fs18 68 (95.8%) \cell +\pard\intbl\qc\fs18 34 (94.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?3 months \cell +\pard\intbl\qc\fs18 41 (93.2%) \cell +\pard\intbl\qc\fs18 24 (88.9%) \cell +\pard\intbl\qc\fs18 65 (91.5%) \cell +\pard\intbl\qc\fs18 34 (94.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?6 months \cell +\pard\intbl\qc\fs18 39 (88.6%) \cell +\pard\intbl\qc\fs18 18 (66.7%) \cell +\pard\intbl\qc\fs18 57 (80.3%) \cell +\pard\intbl\qc\fs18 32 (88.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?12 months \cell +\pard\intbl\qc\fs18 30 (68.2%) \cell +\pard\intbl\qc\fs18 13 (48.1%) \cell +\pard\intbl\qc\fs18 43 (60.6%) \cell +\pard\intbl\qc\fs18 23 (63.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5299 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7766 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10234 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?24 months \cell +\pard\intbl\qc\fs18 15 (34.1%) \cell +\pard\intbl\qc\fs18 6 (22.2%) \cell +\pard\intbl\qc\fs18 21 (29.6%) \cell +\pard\intbl\qc\fs18 12 (33.3%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2831 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5299 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7766 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10234 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4347 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5871 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7395 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8919 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10895 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2831 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5299 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7766 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10234 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsiex02/tsiex02.rtf b/tests/testthat/_snaps/tsiex02/tsiex02.rtf old mode 100755 new mode 100644 index 889f607e..2d676984 --- a/tests/testthat/_snaps/tsiex02/tsiex02.rtf +++ b/tests/testthat/_snaps/tsiex02/tsiex02.rtf @@ -3,68 +3,58 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2859 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4442 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6024 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7607 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3446 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5399 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7409 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX02:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2859 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4442 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6024 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7607 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3446 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5399 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7409 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Total dosing days of treatment (excluding days off treatment)\super a\nosupersub \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Duration of treatment\super a\nosupersub , (months) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -73,194 +63,526 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 99.0 (57.97) \cell -\pard\intbl\qc\fs18 106.7 (56.44) \cell -\pard\intbl\qc\fs18 103.4 (56.98) \cell -\pard\intbl\qc\fs18 93.8 (59.12) \cell +\pard\intbl\qc\fs18 18.44 (9.632) \cell +\pard\intbl\qc\fs18 16.68 (11.322) \cell +\pard\intbl\qc\fs18 17.67 (10.286) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 97.0 \cell -\pard\intbl\qc\fs18 103.0 \cell -\pard\intbl\qc\fs18 102.5 \cell -\pard\intbl\qc\fs18 76.0 \cell +\pard\intbl\qc\fs18 19.10 \cell +\pard\intbl\qc\fs18 15.70 \cell +\pard\intbl\qc\fs18 16.65 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 1, 197 \cell -\pard\intbl\qc\fs18 6, 198 \cell -\pard\intbl\qc\fs18 1, 198 \cell -\pard\intbl\qc\fs18 7, 200 \cell +\pard\intbl\qc\fs18 1.2, 36.7 \cell +\pard\intbl\qc\fs18 0.3, 37.5 \cell +\pard\intbl\qc\fs18 1.1, 36.7 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 48.0, 142.0 \cell -\pard\intbl\qc\fs18 60.0, 159.0 \cell -\pard\intbl\qc\fs18 55.0, 154.0 \cell -\pard\intbl\qc\fs18 51.0, 151.0 \cell +\pard\intbl\qc\fs18 10.00, 26.50 \cell +\pard\intbl\qc\fs18 6.10, 25.90 \cell +\pard\intbl\qc\fs18 8.25, 27.00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total treatment (subject years) \cell +\pard\intbl\qc\fs18 102.941666666667 \cell +\pard\intbl\qc\fs18 70.8833333333333 \cell +\pard\intbl\qc\fs18 94.225 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Difference in means [Study Treatment] vs. [Placebo] (95% CI) \cell +\pard\intbl\qc\fs18 0.77 (-2.80, 4.34) \cell +\pard\intbl\qc\fs18 -0.99 (-4.82, 2.85) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Duration of treatment, n (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 0 to <3 months \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 3 to <6 months \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 6 to <9 months \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 9 to <12 months \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 12 to <15 months \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 15 to <18 months \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 18 to <21 months \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 21 to <24 months \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 24 to <27 months \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 27 to <30 months \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 30 to <33 months \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 33 to <36 months \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 36 to <39 months \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Duration of treatment\super b\nosupersub , n (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cumulative dose ([unit]) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 <1 month \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?1 month \cell +\pard\intbl\qc\fs18 67 (100.0%) \cell +\pard\intbl\qc\fs18 50 (98.0%) \cell +\pard\intbl\qc\fs18 64 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?2 months \cell +\pard\intbl\qc\fs18 65 (97.0%) \cell +\pard\intbl\qc\fs18 47 (92.2%) \cell +\pard\intbl\qc\fs18 62 (96.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?3 months \cell +\pard\intbl\qc\fs18 63 (94.0%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 62 (96.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?6 months \cell +\pard\intbl\qc\fs18 60 (89.6%) \cell +\pard\intbl\qc\fs18 40 (78.4%) \cell +\pard\intbl\qc\fs18 59 (92.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?12 months \cell +\pard\intbl\qc\fs18 45 (67.2%) \cell +\pard\intbl\qc\fs18 32 (62.7%) \cell +\pard\intbl\qc\fs18 39 (60.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 \u8805?24 months \cell +\pard\intbl\qc\fs18 24 (35.8%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 17 (26.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Total dosing days of treatment (excluding days off treatment)\super c\nosupersub \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 2799.3 (1430.11) \cell -\pard\intbl\qc\fs18 2558.4 (1472.53) \cell -\pard\intbl\qc\fs18 2659.7 (1453.97) \cell -\pard\intbl\qc\fs18 2520.5 (1474.47) \cell +\pard\intbl\qc\fs18 106.7 (60.02) \cell +\pard\intbl\qc\fs18 109.5 (56.69) \cell +\pard\intbl\qc\fs18 108.5 (53.20) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 3301.0 \cell -\pard\intbl\qc\fs18 2465.0 \cell -\pard\intbl\qc\fs18 2884.5 \cell -\pard\intbl\qc\fs18 2660.0 \cell +\pard\intbl\qc\fs18 118.0 \cell +\pard\intbl\qc\fs18 115.0 \cell +\pard\intbl\qc\fs18 103.0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 298, 4927 \cell -\pard\intbl\qc\fs18 102, 4978 \cell -\pard\intbl\qc\fs18 102, 4978 \cell -\pard\intbl\qc\fs18 187, 4963 \cell +\pard\intbl\qc\fs18 1, 200 \cell +\pard\intbl\qc\fs18 11, 199 \cell +\pard\intbl\qc\fs18 10, 195 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1561.0, 3984.0 \cell -\pard\intbl\qc\fs18 1177.0, 3859.0 \cell -\pard\intbl\qc\fs18 1326.0, 3914.0 \cell -\pard\intbl\qc\fs18 1118.0, 4098.0 \cell +\pard\intbl\qc\fs18 56.0, 157.0 \cell +\pard\intbl\qc\fs18 52.0, 159.0 \cell +\pard\intbl\qc\fs18 67.5, 157.0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1 to <30 days \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 30 to <60 days \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 60 to <90 days \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?90 days \cell +\pard\intbl\qc\fs18 42 (62.7%) \cell +\pard\intbl\qc\fs18 33 (64.7%) \cell +\pard\intbl\qc\fs18 40 (62.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Average daily dose ([unit/day]) (including days off treatment) \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cumulative dose (mg) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -269,96 +591,82 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 24.57 (11.958) \cell -\pard\intbl\qc\fs18 24.36 (9.463) \cell -\pard\intbl\qc\fs18 24.45 (10.539) \cell -\pard\intbl\qc\fs18 27.44 (10.456) \cell +\pard\intbl\qc\fs18 2707.2 (1405.50) \cell +\pard\intbl\qc\fs18 2469.3 (1314.08) \cell +\pard\intbl\qc\fs18 2308.6 (1471.35) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 23.20 \cell -\pard\intbl\qc\fs18 23.60 \cell -\pard\intbl\qc\fs18 23.40 \cell -\pard\intbl\qc\fs18 28.20 \cell +\pard\intbl\qc\fs18 2825.0 \cell +\pard\intbl\qc\fs18 2588.0 \cell +\pard\intbl\qc\fs18 2047.0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 5.2, 44.9 \cell -\pard\intbl\qc\fs18 5.1, 44.2 \cell -\pard\intbl\qc\fs18 5.1, 44.9 \cell -\pard\intbl\qc\fs18 6.7, 44.5 \cell +\pard\intbl\qc\fs18 167, 4975 \cell +\pard\intbl\qc\fs18 119, 4945 \cell +\pard\intbl\qc\fs18 127, 4773 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 13.80, 35.90 \cell -\pard\intbl\qc\fs18 17.40, 30.20 \cell -\pard\intbl\qc\fs18 16.20, 32.70 \cell -\pard\intbl\qc\fs18 19.50, 35.90 \cell +\pard\intbl\qc\fs18 1557.0, 3924.0 \cell +\pard\intbl\qc\fs18 1241.0, 3493.0 \cell +\pard\intbl\qc\fs18 950.0, 3579.5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Average daily dose ([unit/day]) (excluding days off treatment) \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Average daily dose ([unit]/day) (including days off treatment) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -367,96 +675,166 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 27.43 (12.232) \cell -\pard\intbl\qc\fs18 30.60 (12.574) \cell -\pard\intbl\qc\fs18 29.27 (12.482) \cell -\pard\intbl\qc\fs18 23.88 (12.279) \cell +\pard\intbl\qc\fs18 24.56 (10.880) \cell +\pard\intbl\qc\fs18 24.91 (11.312) \cell +\pard\intbl\qc\fs18 23.54 (12.382) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 25.70 \cell -\pard\intbl\qc\fs18 30.30 \cell -\pard\intbl\qc\fs18 28.10 \cell -\pard\intbl\qc\fs18 21.90 \cell +\pard\intbl\qc\fs18 24.20 \cell +\pard\intbl\qc\fs18 24.80 \cell +\pard\intbl\qc\fs18 22.15 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 6.2, 49.6 \cell -\pard\intbl\qc\fs18 5.0, 50.0 \cell -\pard\intbl\qc\fs18 5.0, 50.0 \cell -\pard\intbl\qc\fs18 6.3, 49.9 \cell +\pard\intbl\qc\fs18 5.1, 43.8 \cell +\pard\intbl\qc\fs18 5.8, 43.6 \cell +\pard\intbl\qc\fs18 5.6, 44.7 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 18.20, 39.00 \cell -\pard\intbl\qc\fs18 20.40, 41.80 \cell -\pard\intbl\qc\fs18 19.30, 39.40 \cell -\pard\intbl\qc\fs18 12.80, 34.10 \cell +\pard\intbl\qc\fs18 15.20, 33.00 \cell +\pard\intbl\qc\fs18 17.50, 34.90 \cell +\pard\intbl\qc\fs18 11.75, 32.95 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Average daily dose ([unit]/day) (excluding days off treatment) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Modal daily dose ([unit/day]), n (%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 27.51 (14.192) \cell +\pard\intbl\qc\fs18 28.83 (12.662) \cell +\pard\intbl\qc\fs18 29.04 (12.655) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 26.30 \cell +\pard\intbl\qc\fs18 30.10 \cell +\pard\intbl\qc\fs18 30.10 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 5.4, 49.3 \cell +\pard\intbl\qc\fs18 7.1, 49.0 \cell +\pard\intbl\qc\fs18 6.0, 49.6 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 14.80, 39.50 \cell +\pard\intbl\qc\fs18 16.90, 40.40 \cell +\pard\intbl\qc\fs18 18.45, 39.90 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Modal daily dose ([unit]/day), n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -465,82 +843,70 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 20 mg \cell -\pard\intbl\qc\fs18 18 (34.0%) \cell -\pard\intbl\qc\fs18 19 (26.0%) \cell -\pard\intbl\qc\fs18 37 (29.4%) \cell -\pard\intbl\qc\fs18 17 (28.8%) \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 18 (28.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 30 mg \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 15 (20.5%) \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 14 (23.7%) \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 19 (37.3%) \cell +\pard\intbl\qc\fs18 10 (15.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 40 mg \cell -\pard\intbl\qc\fs18 24 (45.3%) \cell -\pard\intbl\qc\fs18 39 (53.4%) \cell -\pard\intbl\qc\fs18 63 (50.0%) \cell -\pard\intbl\qc\fs18 28 (47.5%) \cell +\pard\intbl\qc\fs18 38 (56.7%) \cell +\pard\intbl\qc\fs18 22 (43.1%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Final daily dose ([unit/day]) \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Final daily dose ([unit]/day) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -549,96 +915,82 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 32.6 (10.50) \cell -\pard\intbl\qc\fs18 29.1 (10.55) \cell -\pard\intbl\qc\fs18 30.6 (10.63) \cell -\pard\intbl\qc\fs18 28.5 (12.33) \cell +\pard\intbl\qc\fs18 28.3 (10.48) \cell +\pard\intbl\qc\fs18 28.8 (11.86) \cell +\pard\intbl\qc\fs18 31.4 (11.41) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 34.0 \cell -\pard\intbl\qc\fs18 27.0 \cell -\pard\intbl\qc\fs18 31.0 \cell -\pard\intbl\qc\fs18 27.0 \cell +\pard\intbl\qc\fs18 28.0 \cell +\pard\intbl\qc\fs18 29.0 \cell +\pard\intbl\qc\fs18 32.5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 11, 50 \cell \pard\intbl\qc\fs18 11, 49 \cell \pard\intbl\qc\fs18 12, 49 \cell -\pard\intbl\qc\fs18 11, 49 \cell -\pard\intbl\qc\fs18 10, 49 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 25.0, 40.0 \cell -\pard\intbl\qc\fs18 21.0, 37.0 \cell -\pard\intbl\qc\fs18 22.0, 38.0 \cell -\pard\intbl\qc\fs18 17.0, 40.0 \cell +\pard\intbl\qc\fs18 19.0, 36.0 \cell +\pard\intbl\qc\fs18 18.0, 39.0 \cell +\pard\intbl\qc\fs18 19.5, 41.0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell -\pard\intbl\qc\fs18 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Final daily dose ([unit/day]), n (%) \cell -\pard\intbl\qc\fs18 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Final daily dose ([unit]/day), n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -647,71 +999,61 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 20 mg \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 26 (20.6%) \cell -\pard\intbl\qc\fs18 20 (33.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 20 mg \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 17 (26.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 30 mg \cell -\pard\intbl\qc\fs18 14 (26.4%) \cell -\pard\intbl\qc\fs18 22 (30.1%) \cell -\pard\intbl\qc\fs18 36 (28.6%) \cell -\pard\intbl\qc\fs18 13 (22.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 30 mg \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 12 (18.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 40 mg \cell -\pard\intbl\qc\fs18 31 (58.5%) \cell -\pard\intbl\qc\fs18 33 (45.2%) \cell -\pard\intbl\qc\fs18 64 (50.8%) \cell -\pard\intbl\qc\fs18 26 (44.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3446 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5399 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7409 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 40 mg \cell +\pard\intbl\qc\fs18 31 (46.3%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 35 (54.7%) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4442 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6024 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7607 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3446 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5399 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7409 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3446 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5399 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7409 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell -\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsiex02b/tsiex02b.rtf b/tests/testthat/_snaps/tsiex02b/tsiex02b.rtf new file mode 100644 index 00000000..7f8d85b1 --- /dev/null +++ b/tests/testthat/_snaps/tsiex02b/tsiex02b.rtf @@ -0,0 +1,5506 @@ +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3431 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4840 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6249 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7780 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX02b:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3431 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4840 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6249 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7780 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Action Taken or Dose Delay \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Reason, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Any action taken or dose delay of study treatment\super a\nosupersub \cell +\pard\intbl\qc\fs18 67 (100.0%) \cell +\pard\intbl\qc\fs18 51 (100.0%) \cell +\pard\intbl\qc\fs18 118 (100.0%) \cell +\pard\intbl\qc\fs18 64 (100.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 14 (27.5%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 17 (25.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 26 (22.0%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 20 (16.9%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 37 (31.4%) \cell +\pard\intbl\qc\fs18 24 (37.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 35 (29.7%) \cell +\pard\intbl\qc\fs18 22 (34.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 21 (41.2%) \cell +\pard\intbl\qc\fs18 39 (33.1%) \cell +\pard\intbl\qc\fs18 27 (42.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose delay \cell +\pard\intbl\qc\fs18 42 (62.7%) \cell +\pard\intbl\qc\fs18 34 (66.7%) \cell +\pard\intbl\qc\fs18 76 (64.4%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Anemia \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infection \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Low neutrophil count \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missed visit \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Non-hematologic toxicity \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Pending lab results \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Recovery from toxicity \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Thrombocytopenia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Period 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken to prescribed dose compared to prior \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 8 (21.1%) \cell +\pard\intbl\qc\fs18 12 (13.2%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 15 (28.3%) \cell +\pard\intbl\qc\fs18 8 (21.1%) \cell +\pard\intbl\qc\fs18 23 (25.3%) \cell +\pard\intbl\qc\fs18 7 (14.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 5 (9.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (5.5%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 5 (9.4%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 7 (13.2%) \cell +\pard\intbl\qc\fs18 8 (21.1%) \cell +\pard\intbl\qc\fs18 15 (16.5%) \cell +\pard\intbl\qc\fs18 8 (17.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 5 (5.5%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 10 (18.9%) \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 14 (15.4%) \cell +\pard\intbl\qc\fs18 7 (14.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 6 (11.3%) \cell +\pard\intbl\qc\fs18 10 (26.3%) \cell +\pard\intbl\qc\fs18 16 (17.6%) \cell +\pard\intbl\qc\fs18 8 (17.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 5 (13.2%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken with study treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 16 (30.2%) \cell +\pard\intbl\qc\fs18 12 (31.6%) \cell +\pard\intbl\qc\fs18 28 (30.8%) \cell +\pard\intbl\qc\fs18 19 (40.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 7 (7.7%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 8 (8.8%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 5 (5.5%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 13 (24.5%) \cell +\pard\intbl\qc\fs18 14 (36.8%) \cell +\pard\intbl\qc\fs18 27 (29.7%) \cell +\pard\intbl\qc\fs18 16 (34.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 5 (13.2%) \cell +\pard\intbl\qc\fs18 8 (8.8%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 5 (9.4%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 7 (7.7%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 14 (26.4%) \cell +\pard\intbl\qc\fs18 16 (42.1%) \cell +\pard\intbl\qc\fs18 30 (33.0%) \cell +\pard\intbl\qc\fs18 17 (36.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 6 (11.3%) \cell +\pard\intbl\qc\fs18 6 (15.8%) \cell +\pard\intbl\qc\fs18 12 (13.2%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 7 (7.7%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Period 2 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken to prescribed dose compared to prior \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 6 (31.6%) \cell +\pard\intbl\qc\fs18 9 (22.0%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 2 (9.1%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 5 (19.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 4 (21.1%) \cell +\pard\intbl\qc\fs18 5 (12.2%) \cell +\pard\intbl\qc\fs18 7 (26.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 6 (14.6%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken with study treatment \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 6 (31.6%) \cell +\pard\intbl\qc\fs18 9 (22.0%) \cell +\pard\intbl\qc\fs18 6 (23.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (9.1%) \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 6 (27.3%) \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 9 (22.0%) \cell +\pard\intbl\qc\fs18 7 (26.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (9.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 4 (18.2%) \cell +\pard\intbl\qc\fs18 6 (31.6%) \cell +\pard\intbl\qc\fs18 10 (24.4%) \cell +\pard\intbl\qc\fs18 10 (38.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 4 (15.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 4 (15.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Screening \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken to prescribed dose compared to prior \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken with study treatment \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 20 (16.9%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 16 (13.6%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 20 (16.9%) \cell +\pard\intbl\qc\fs18 15 (23.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken to prescribed dose compared to prior \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (12.2%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 6 (12.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (11.2%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 7 (7.1%) \cell +\pard\intbl\qc\fs18 7 (11.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (8.2%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (6.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken with study treatment \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 8 (17.0%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 18 (18.4%) \cell +\pard\intbl\qc\fs18 12 (19.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 5 (8.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 11 (23.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 19 (19.4%) \cell +\pard\intbl\qc\fs18 13 (21.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 7 (7.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 4 (6.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 6 (12.8%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 15 (15.3%) \cell +\pard\intbl\qc\fs18 9 (14.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (6.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 09 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken to prescribed dose compared to prior \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 5 (25.0%) \cell +\pard\intbl\qc\fs18 7 (17.9%) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 4 (10.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 8 (20.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 4 (10.3%) \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken with study treatment \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 3 (15.0%) \cell +\pard\intbl\qc\fs18 4 (10.3%) \cell +\pard\intbl\qc\fs18 9 (22.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 4 (10.3%) \cell +\pard\intbl\qc\fs18 6 (15.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 5 (26.3%) \cell +\pard\intbl\qc\fs18 7 (35.0%) \cell +\pard\intbl\qc\fs18 12 (30.8%) \cell +\pard\intbl\qc\fs18 8 (20.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 4 (10.3%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 4 (10.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3431 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4840 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6249 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7780 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3431 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4840 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6249 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7780 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3431 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4840 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6249 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7780 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsiex03/tsiex03.rtf b/tests/testthat/_snaps/tsiex03/tsiex03.rtf old mode 100755 new mode 100644 index 28ac03a2..e1a86b50 --- a/tests/testthat/_snaps/tsiex03/tsiex03.rtf +++ b/tests/testthat/_snaps/tsiex03/tsiex03.rtf @@ -1,13 +1,13 @@ -{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2859 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4442 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6024 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7607 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX03:\tab Dummy Title\b0 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2840 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5380 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7995 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10385 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX03:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -17,11 +17,11 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2859 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4442 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6024 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7607 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2840 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5380 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7995 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10385 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -31,13 +31,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row @@ -45,25 +45,361 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Duration of treatment\super a\nosupersub , (months) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 18.44 (9.632) \cell +\pard\intbl\qc\fs18 16.68 (11.322) \cell +\pard\intbl\qc\fs18 17.68 (10.387) \cell +\pard\intbl\qc\fs18 17.67 (10.286) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 19.10 \cell +\pard\intbl\qc\fs18 15.70 \cell +\pard\intbl\qc\fs18 17.40 \cell +\pard\intbl\qc\fs18 16.65 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 1.2, 36.7 \cell +\pard\intbl\qc\fs18 0.3, 37.5 \cell +\pard\intbl\qc\fs18 0.3, 37.5 \cell +\pard\intbl\qc\fs18 1.1, 36.7 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 10.00, 26.50 \cell +\pard\intbl\qc\fs18 6.10, 25.90 \cell +\pard\intbl\qc\fs18 9.00, 25.90 \cell +\pard\intbl\qc\fs18 8.25, 27.00 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Total treatment (subject years) \cell +\pard\intbl\qc\fs18 102.941666666667 \cell +\pard\intbl\qc\fs18 70.8833333333333 \cell +\pard\intbl\qc\fs18 173.825 \cell +\pard\intbl\qc\fs18 94.225 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Difference in means [Study Treatment] vs. [Placebo] (95% CI) \cell +\pard\intbl\qc\fs18 0.77 (-2.80, 4.34) \cell +\pard\intbl\qc\fs18 -0.99 (-4.82, 2.85) \cell +\pard\intbl\qc\fs18 0.01 (-3.16, 3.18) \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Duration of treatment, n (%) \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 0 to <3 months \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 3 to <6 months \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 6 to <9 months \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 9 to <12 months \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 12 to <15 months \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 15 to <18 months \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 18 to <21 months \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 21 to <24 months \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 24 to <27 months \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Total number of administrations \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 27 to <30 months \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 30 to <33 months \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 33 to <36 months \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 36 to <39 months \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Duration of treatment\super b\nosupersub , n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -73,81 +409,207 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 <1 month \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?1 month \cell +\pard\intbl\qc\fs18 67 (100.0%) \cell +\pard\intbl\qc\fs18 50 (98.0%) \cell +\pard\intbl\qc\fs18 117 (99.2%) \cell +\pard\intbl\qc\fs18 64 (100.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 12.6 (9.24) \cell -\pard\intbl\qc\fs18 15.0 (8.78) \cell -\pard\intbl\qc\fs18 14.0 (9.02) \cell -\pard\intbl\qc\fs18 16.1 (9.01) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 months \cell +\pard\intbl\qc\fs18 65 (97.0%) \cell +\pard\intbl\qc\fs18 47 (92.2%) \cell +\pard\intbl\qc\fs18 112 (94.9%) \cell +\pard\intbl\qc\fs18 62 (96.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 11.0 \cell -\pard\intbl\qc\fs18 16.0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?3 months \cell +\pard\intbl\qc\fs18 63 (94.0%) \cell +\pard\intbl\qc\fs18 46 (90.2%) \cell +\pard\intbl\qc\fs18 109 (92.4%) \cell +\pard\intbl\qc\fs18 62 (96.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?6 months \cell +\pard\intbl\qc\fs18 60 (89.6%) \cell +\pard\intbl\qc\fs18 40 (78.4%) \cell +\pard\intbl\qc\fs18 100 (84.7%) \cell +\pard\intbl\qc\fs18 59 (92.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?12 months \cell +\pard\intbl\qc\fs18 45 (67.2%) \cell +\pard\intbl\qc\fs18 32 (62.7%) \cell +\pard\intbl\qc\fs18 77 (65.3%) \cell +\pard\intbl\qc\fs18 39 (60.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?24 months \cell +\pard\intbl\qc\fs18 24 (35.8%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 37 (31.4%) \cell +\pard\intbl\qc\fs18 17 (26.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Total number of administrations \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 14.1 (8.32) \cell +\pard\intbl\qc\fs18 13.7 (8.88) \cell +\pard\intbl\qc\fs18 13.9 (8.53) \cell +\pard\intbl\qc\fs18 13.8 (8.69) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 13.0 \cell +\pard\intbl\qc\fs18 12.0 \cell +\pard\intbl\qc\fs18 13.0 \cell \pard\intbl\qc\fs18 15.0 \cell -\pard\intbl\qc\fs18 17.0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0, 29 \cell -\pard\intbl\qc\fs18 0, 29 \cell -\pard\intbl\qc\fs18 0, 29 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 1, 29 \cell +\pard\intbl\qc\fs18 0, 30 \cell +\pard\intbl\qc\fs18 0, 30 \cell \pard\intbl\qc\fs18 0, 30 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 4.0, 21.0 \cell -\pard\intbl\qc\fs18 7.0, 23.0 \cell -\pard\intbl\qc\fs18 5.0, 22.0 \cell -\pard\intbl\qc\fs18 8.0, 24.0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 8.0, 22.0 \cell +\pard\intbl\qc\fs18 6.0, 20.0 \cell +\pard\intbl\qc\fs18 7.0, 21.0 \cell +\pard\intbl\qc\fs18 5.0, 20.5 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -157,11 +619,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of administrations, n (%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of administrations, n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -171,53 +633,53 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1 to <10 \cell -\pard\intbl\qc\fs18 19 (38.0%) \cell -\pard\intbl\qc\fs18 21 (29.6%) \cell -\pard\intbl\qc\fs18 40 (33.1%) \cell -\pard\intbl\qc\fs18 15 (26.3%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1 to <10 \cell +\pard\intbl\qc\fs18 24 (35.8%) \cell +\pard\intbl\qc\fs18 15 (29.4%) \cell +\pard\intbl\qc\fs18 39 (33.1%) \cell +\pard\intbl\qc\fs18 19 (29.7%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 10 to <20 \cell -\pard\intbl\qc\fs18 13 (26.0%) \cell -\pard\intbl\qc\fs18 22 (31.0%) \cell -\pard\intbl\qc\fs18 35 (28.9%) \cell -\pard\intbl\qc\fs18 15 (26.3%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 10 to <20 \cell +\pard\intbl\qc\fs18 25 (37.3%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 43 (36.4%) \cell +\pard\intbl\qc\fs18 26 (40.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?20 \cell -\pard\intbl\qc\fs18 18 (36.0%) \cell -\pard\intbl\qc\fs18 28 (39.4%) \cell -\pard\intbl\qc\fs18 46 (38.0%) \cell -\pard\intbl\qc\fs18 27 (47.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?20 \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 35 (29.7%) \cell +\pard\intbl\qc\fs18 17 (26.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -227,11 +689,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of administrations\super a\nosupersub , n (%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Total number of administrations\super b\nosupersub , n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -241,81 +703,81 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?1 \cell -\pard\intbl\qc\fs18 53 (100.0%) \cell -\pard\intbl\qc\fs18 73 (100.0%) \cell -\pard\intbl\qc\fs18 126 (100.0%) \cell -\pard\intbl\qc\fs18 59 (100.0%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?1 \cell +\pard\intbl\qc\fs18 67 (100.0%) \cell +\pard\intbl\qc\fs18 50 (98.0%) \cell +\pard\intbl\qc\fs18 117 (99.2%) \cell +\pard\intbl\qc\fs18 62 (96.9%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 \cell -\pard\intbl\qc\fs18 47 (88.7%) \cell -\pard\intbl\qc\fs18 68 (93.2%) \cell -\pard\intbl\qc\fs18 115 (91.3%) \cell -\pard\intbl\qc\fs18 56 (94.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?2 \cell +\pard\intbl\qc\fs18 64 (95.5%) \cell +\pard\intbl\qc\fs18 47 (92.2%) \cell +\pard\intbl\qc\fs18 111 (94.1%) \cell +\pard\intbl\qc\fs18 61 (95.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?3 \cell -\pard\intbl\qc\fs18 45 (84.9%) \cell -\pard\intbl\qc\fs18 66 (90.4%) \cell -\pard\intbl\qc\fs18 111 (88.1%) \cell -\pard\intbl\qc\fs18 54 (91.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?3 \cell +\pard\intbl\qc\fs18 59 (88.1%) \cell +\pard\intbl\qc\fs18 45 (88.2%) \cell +\pard\intbl\qc\fs18 104 (88.1%) \cell +\pard\intbl\qc\fs18 58 (90.6%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?5 \cell -\pard\intbl\qc\fs18 36 (67.9%) \cell -\pard\intbl\qc\fs18 61 (83.6%) \cell -\pard\intbl\qc\fs18 97 (77.0%) \cell -\pard\intbl\qc\fs18 50 (84.7%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?5 \cell +\pard\intbl\qc\fs18 58 (86.6%) \cell +\pard\intbl\qc\fs18 41 (80.4%) \cell +\pard\intbl\qc\fs18 99 (83.9%) \cell +\pard\intbl\qc\fs18 50 (78.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?10 \cell -\pard\intbl\qc\fs18 31 (58.5%) \cell -\pard\intbl\qc\fs18 50 (68.5%) \cell -\pard\intbl\qc\fs18 81 (64.3%) \cell -\pard\intbl\qc\fs18 42 (71.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?10 \cell +\pard\intbl\qc\fs18 43 (64.2%) \cell +\pard\intbl\qc\fs18 35 (68.6%) \cell +\pard\intbl\qc\fs18 78 (66.1%) \cell +\pard\intbl\qc\fs18 43 (67.2%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -325,11 +787,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cumulative dose ([units]) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cumulative dose (mg) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -339,81 +801,81 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 2799.3 (1430.11) \cell -\pard\intbl\qc\fs18 2558.4 (1472.53) \cell -\pard\intbl\qc\fs18 2659.7 (1453.97) \cell -\pard\intbl\qc\fs18 2520.5 (1474.47) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell +\pard\intbl\qc\fs18 2707.2 (1405.50) \cell +\pard\intbl\qc\fs18 2469.3 (1314.08) \cell +\pard\intbl\qc\fs18 2604.4 (1366.13) \cell +\pard\intbl\qc\fs18 2308.6 (1471.35) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 3301.0 \cell -\pard\intbl\qc\fs18 2465.0 \cell -\pard\intbl\qc\fs18 2884.5 \cell -\pard\intbl\qc\fs18 2660.0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell +\pard\intbl\qc\fs18 2825.0 \cell +\pard\intbl\qc\fs18 2588.0 \cell +\pard\intbl\qc\fs18 2620.5 \cell +\pard\intbl\qc\fs18 2047.0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 298, 4927 \cell -\pard\intbl\qc\fs18 102, 4978 \cell -\pard\intbl\qc\fs18 102, 4978 \cell -\pard\intbl\qc\fs18 187, 4963 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell +\pard\intbl\qc\fs18 167, 4975 \cell +\pard\intbl\qc\fs18 119, 4945 \cell +\pard\intbl\qc\fs18 119, 4975 \cell +\pard\intbl\qc\fs18 127, 4773 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2859 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4442 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6024 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7607 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell -\pard\intbl\qc\fs18 1561.0, 3984.0 \cell -\pard\intbl\qc\fs18 1177.0, 3859.0 \cell -\pard\intbl\qc\fs18 1326.0, 3914.0 \cell -\pard\intbl\qc\fs18 1118.0, 4098.0 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2840 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5380 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7995 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10385 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Interquartile range \cell +\pard\intbl\qc\fs18 1557.0, 3924.0 \cell +\pard\intbl\qc\fs18 1241.0, 3493.0 \cell +\pard\intbl\qc\fs18 1489.0, 3784.0 \cell +\pard\intbl\qc\fs18 950.0, 3579.5 \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4442 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6024 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7607 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2840 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5380 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7995 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10385 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -423,11 +885,11 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2859 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4442 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6024 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7607 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2840 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5380 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7995 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10385 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsiex03b/tsiex03b.rtf b/tests/testthat/_snaps/tsiex03b/tsiex03b.rtf new file mode 100644 index 00000000..ec5188da --- /dev/null +++ b/tests/testthat/_snaps/tsiex03b/tsiex03b.rtf @@ -0,0 +1,5506 @@ +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3429 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4869 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6309 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7749 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX03b:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx3429 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4869 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6309 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7749 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Action Taken or Dose Delay \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Reason, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Any action taken or dose delay of study treatment\super a\nosupersub \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 14 (27.5%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 17 (25.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 26 (22.0%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 18 (15.3%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 20 (16.9%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 18 (35.3%) \cell +\pard\intbl\qc\fs18 37 (31.4%) \cell +\pard\intbl\qc\fs18 24 (37.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 17 (33.3%) \cell +\pard\intbl\qc\fs18 35 (29.7%) \cell +\pard\intbl\qc\fs18 22 (34.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 8 (11.9%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 6 (9.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 7 (10.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 18 (26.9%) \cell +\pard\intbl\qc\fs18 21 (41.2%) \cell +\pard\intbl\qc\fs18 39 (33.1%) \cell +\pard\intbl\qc\fs18 27 (42.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose delay \cell +\pard\intbl\qc\fs18 42 (62.7%) \cell +\pard\intbl\qc\fs18 34 (66.7%) \cell +\pard\intbl\qc\fs18 76 (64.4%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Anemia \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infection \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Low neutrophil count \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Missed visit \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 9 (7.6%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Non-hematologic toxicity \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Pending lab results \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 12 (10.2%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 6 (11.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Recovery from toxicity \cell +\pard\intbl\qc\fs18 4 (6.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Subject request \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 11 (17.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Thrombocytopenia \cell +\pard\intbl\qc\fs18 6 (9.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 8 (6.8%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Period 1 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken prior to [injection/infusion] \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 8 (21.1%) \cell +\pard\intbl\qc\fs18 12 (13.2%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 15 (28.3%) \cell +\pard\intbl\qc\fs18 8 (21.1%) \cell +\pard\intbl\qc\fs18 23 (25.3%) \cell +\pard\intbl\qc\fs18 7 (14.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 5 (9.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (5.5%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 5 (9.4%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 7 (13.2%) \cell +\pard\intbl\qc\fs18 8 (21.1%) \cell +\pard\intbl\qc\fs18 15 (16.5%) \cell +\pard\intbl\qc\fs18 8 (17.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 5 (5.5%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 10 (18.9%) \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 14 (15.4%) \cell +\pard\intbl\qc\fs18 7 (14.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 6 (11.3%) \cell +\pard\intbl\qc\fs18 10 (26.3%) \cell +\pard\intbl\qc\fs18 16 (17.6%) \cell +\pard\intbl\qc\fs18 8 (17.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 5 (13.2%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (1.1%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken during [injection/infusion] \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 16 (30.2%) \cell +\pard\intbl\qc\fs18 12 (31.6%) \cell +\pard\intbl\qc\fs18 28 (30.8%) \cell +\pard\intbl\qc\fs18 19 (40.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 7 (7.7%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 8 (8.8%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 5 (5.5%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 13 (24.5%) \cell +\pard\intbl\qc\fs18 14 (36.8%) \cell +\pard\intbl\qc\fs18 27 (29.7%) \cell +\pard\intbl\qc\fs18 16 (34.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 5 (13.2%) \cell +\pard\intbl\qc\fs18 8 (8.8%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 5 (9.4%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 7 (7.7%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 2 (2.2%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 14 (26.4%) \cell +\pard\intbl\qc\fs18 16 (42.1%) \cell +\pard\intbl\qc\fs18 30 (33.0%) \cell +\pard\intbl\qc\fs18 17 (36.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 6 (11.3%) \cell +\pard\intbl\qc\fs18 6 (15.8%) \cell +\pard\intbl\qc\fs18 12 (13.2%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 4 (7.5%) \cell +\pard\intbl\qc\fs18 2 (5.3%) \cell +\pard\intbl\qc\fs18 6 (6.6%) \cell +\pard\intbl\qc\fs18 4 (8.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (5.7%) \cell +\pard\intbl\qc\fs18 4 (10.5%) \cell +\pard\intbl\qc\fs18 7 (7.7%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.9%) \cell +\pard\intbl\qc\fs18 3 (7.9%) \cell +\pard\intbl\qc\fs18 4 (4.4%) \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.8%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 3 (3.3%) \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Period 2 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken prior to [injection/infusion] \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 6 (31.6%) \cell +\pard\intbl\qc\fs18 9 (22.0%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 2 (9.1%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 5 (19.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 4 (21.1%) \cell +\pard\intbl\qc\fs18 5 (12.2%) \cell +\pard\intbl\qc\fs18 7 (26.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 6 (14.6%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken during [injection/infusion] \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 6 (31.6%) \cell +\pard\intbl\qc\fs18 9 (22.0%) \cell +\pard\intbl\qc\fs18 6 (23.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (9.1%) \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 6 (27.3%) \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 9 (22.0%) \cell +\pard\intbl\qc\fs18 7 (26.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (9.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (13.6%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 4 (9.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.4%) \cell +\pard\intbl\qc\fs18 3 (11.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 4 (18.2%) \cell +\pard\intbl\qc\fs18 6 (31.6%) \cell +\pard\intbl\qc\fs18 10 (24.4%) \cell +\pard\intbl\qc\fs18 10 (38.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 4 (15.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 2 (7.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (4.9%) \cell +\pard\intbl\qc\fs18 1 (3.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (4.5%) \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 3 (7.3%) \cell +\pard\intbl\qc\fs18 4 (15.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Screening \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken prior to [injection/infusion] \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 12 (17.9%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 17 (14.4%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 6 (5.1%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 10 (8.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 11 (9.3%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 14 (11.9%) \cell +\pard\intbl\qc\fs18 5 (7.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken during [injection/infusion] \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 20 (16.9%) \cell +\pard\intbl\qc\fs18 8 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 7 (10.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 16 (13.6%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\pard\intbl\qc\fs18 2 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 11 (16.4%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 20 (16.9%) \cell +\pard\intbl\qc\fs18 15 (23.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 5 (4.2%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 2 (3.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (1.7%) \cell +\pard\intbl\qc\fs18 3 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 3 (4.5%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (3.4%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (1.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (2.5%) \cell +\pard\intbl\qc\fs18 4 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken prior to [injection/infusion] \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 12 (12.2%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 6 (12.8%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 11 (11.2%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 7 (7.1%) \cell +\pard\intbl\qc\fs18 7 (11.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 8 (8.2%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 6 (6.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken during [injection/infusion] \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 8 (17.0%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 18 (18.4%) \cell +\pard\intbl\qc\fs18 12 (19.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 5 (5.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 5 (8.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (5.9%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 11 (23.4%) \cell +\pard\intbl\qc\fs18 8 (15.7%) \cell +\pard\intbl\qc\fs18 19 (19.4%) \cell +\pard\intbl\qc\fs18 13 (21.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 3 (6.4%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 3 (4.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 5 (10.6%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 7 (7.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 4 (6.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 6 (12.8%) \cell +\pard\intbl\qc\fs18 9 (17.6%) \cell +\pard\intbl\qc\fs18 15 (15.3%) \cell +\pard\intbl\qc\fs18 9 (14.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 2 (4.3%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 1 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (7.8%) \cell +\pard\intbl\qc\fs18 4 (4.1%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (2.1%) \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 2 (2.0%) \cell +\pard\intbl\qc\fs18 2 (3.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (6.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 09 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken prior to [injection/infusion] \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Dose reduced \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 5 (25.0%) \cell +\pard\intbl\qc\fs18 7 (17.9%) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion delayed \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate decreased \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 4 (10.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion skipped \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 8 (20.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Study agent permanently discontinued \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 4 (10.3%) \cell +\pard\intbl\qc\fs18 3 (7.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Action taken during [injection/infusion] \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion aborted \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 3 (15.0%) \cell +\pard\intbl\qc\fs18 4 (10.3%) \cell +\pard\intbl\qc\fs18 9 (22.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (12.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion interrupted \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 4 (10.3%) \cell +\pard\intbl\qc\fs18 6 (15.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 2 (5.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Infusion rate increased \cell +\pard\intbl\qc\fs18 5 (26.3%) \cell +\pard\intbl\qc\fs18 7 (35.0%) \cell +\pard\intbl\qc\fs18 12 (30.8%) \cell +\pard\intbl\qc\fs18 8 (20.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Administrative reason \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 4 (10.3%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Medical reason \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (10.0%) \cell +\pard\intbl\qc\fs18 2 (5.1%) \cell +\pard\intbl\qc\fs18 4 (10.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Other \cell +\pard\intbl\qc\fs18 1 (5.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Physician decision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3429 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4869 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6309 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7749 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Subject request \cell +\pard\intbl\qc\fs18 2 (10.5%) \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 3 (7.7%) \cell +\pard\intbl\qc\fs18 1 (2.5%) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3429 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4869 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6309 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7749 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3429 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4869 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6309 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7749 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsfae24b/tsfae24b.rtf b/tests/testthat/_snaps/tsiex05/tsiex05.rtf old mode 100755 new mode 100644 similarity index 59% rename from tests/testthat/_snaps/tsfae24b/tsfae24b.rtf rename to tests/testthat/_snaps/tsiex05/tsiex05.rtf index e681ae96..f2c10bac --- a/tests/testthat/_snaps/tsfae24b/tsfae24b.rtf +++ b/tests/testthat/_snaps/tsiex05/tsiex05.rtf @@ -6,7 +6,7 @@ \trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFAE24b:\tab Dummy Title\b0 \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX05:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -18,10 +18,10 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2828 \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4948 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7069 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr \cell \row } @@ -30,10 +30,10 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell -\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \row } @@ -42,10 +42,10 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2828 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4948 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Dose Modification, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell \row } @@ -54,10 +54,46 @@ \trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805? 1 AE \cell -\pard\intbl\qc\fs18 51 (96.2%) \cell -\pard\intbl\qc\fs18 55 (75.3%) \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Prescribed dose reductions \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?1 dose reduction \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 11 (21.6%) \cell +\pard\intbl\qc\fs18 21 (17.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 To 7.5 mg \cell +\pard\intbl\qc\fs18 10 (14.9%) \cell +\pard\intbl\qc\fs18 5 (9.8%) \cell +\pard\intbl\qc\fs18 15 (12.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 To 15 mg \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell \row } @@ -78,7 +114,55 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Toxicity grade \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Prescribed dose reductions due to AEs \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?1 dose reduction \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 To 7.5 mg \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 To 15 mg \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -90,10 +174,10 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 5 \cell -\pard\intbl\qc\fs18 26 (49.1%) \cell -\pard\intbl\qc\fs18 19 (26.0%) \cell -\pard\intbl\qc\fs18 11 (18.6%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Dose interruptions \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell \row } @@ -102,10 +186,10 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 4 \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 16 (21.9%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?1 dose interruptions \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell \row } @@ -114,10 +198,10 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 3 \cell -\pard\intbl\qc\fs18 6 (11.3%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 7 (11.9%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 1 \cell +\pard\intbl\qc\fs18 5 (7.5%) \cell +\pard\intbl\qc\fs18 2 (3.9%) \cell +\pard\intbl\qc\fs18 7 (5.9%) \cell \row } @@ -126,10 +210,10 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2828 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4948 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 2 \cell -\pard\intbl\qc\fs18 7 (13.2%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 2 (3.4%) \cell +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 2 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \row } @@ -138,10 +222,10 @@ \trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2828 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4948 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7069 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Grade 1 \cell +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?3 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (4.1%) \cell -\pard\intbl\qc\fs18 5 (8.5%) \cell \row } diff --git a/tests/testthat/_snaps/tsiex06/tsiex06.rtf b/tests/testthat/_snaps/tsiex06/tsiex06.rtf old mode 100755 new mode 100644 index b7e3c05e..cd54f9f3 --- a/tests/testthat/_snaps/tsiex06/tsiex06.rtf +++ b/tests/testthat/_snaps/tsiex06/tsiex06.rtf @@ -3,10 +3,10 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2867 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4411 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6102 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7646 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX06:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -17,10 +17,10 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2863 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4444 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6026 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7608 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2867 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4411 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6102 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7646 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -31,13 +31,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6102 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row @@ -45,24 +45,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6102 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7646 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li90\fi0 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6102 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects receiving study treatment, n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -73,52 +73,38 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Baseline \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 42 (57.5%) \cell -\pard\intbl\qc\fs18 72 (57.1%) \cell -\pard\intbl\qc\fs18 21 (35.6%) \cell -\row -} - -{ -\trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Week 2 \cell -\pard\intbl\qc\fs18 27 (50.9%) \cell -\pard\intbl\qc\fs18 16 (21.9%) \cell -\pard\intbl\qc\fs18 43 (34.1%) \cell -\pard\intbl\qc\fs18 28 (47.5%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6102 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 47 (70.1%) \cell +\pard\intbl\qc\fs18 51 (100.0%) \cell +\pard\intbl\qc\fs18 98 (83.1%) \cell +\pard\intbl\qc\fs18 61 (95.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Week 24 \cell -\pard\intbl\qc\fs18 14 (26.4%) \cell -\pard\intbl\qc\fs18 8 (11.0%) \cell -\pard\intbl\qc\fs18 22 (17.5%) \cell -\pard\intbl\qc\fs18 19 (32.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6102 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7646 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 09 \cell +\pard\intbl\qc\fs18 19 (28.4%) \cell +\pard\intbl\qc\fs18 20 (39.2%) \cell +\pard\intbl\qc\fs18 39 (33.1%) \cell +\pard\intbl\qc\fs18 40 (62.5%) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2867 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4411 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6102 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7646 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -129,10 +115,10 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6102 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7646 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsiex07/tsiex07.rtf b/tests/testthat/_snaps/tsiex07/tsiex07.rtf old mode 100755 new mode 100644 index 4a4443e7..dfe34aec --- a/tests/testthat/_snaps/tsiex07/tsiex07.rtf +++ b/tests/testthat/_snaps/tsiex07/tsiex07.rtf @@ -3,199 +3,97 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2849 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3977 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5105 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6351 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7479 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8725 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9971 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11218 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2806 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5908 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9305 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX07:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell -\pard\intbl\ql\fs20 \b \b0 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2849 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx3977 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5105 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6351 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7479 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8725 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9971 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx11218 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2806 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5908 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9305 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell -\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3977 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5105 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7479 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8725 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9971 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11218 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5908 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9305 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr 60 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 120 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 240 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 300 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 480 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 720 \cell -\pard\intbl\qc\fs18 \keepn\trhdr 960 \cell +\pard\intbl\qc\fs18 \keepn\trhdr 7.5 \cell +\pard\intbl\qc\fs18 \keepn\trhdr 15 \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx3977 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5105 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7479 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8725 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9971 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx11218 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2806 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5908 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9305 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Time Point, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=3 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=3 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=3 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=8 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=26 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=66 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=50 \cell \pard\intbl\qc\fs18 \keepn\trhdr N=98 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=125 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3977 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5105 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7479 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8725 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9971 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11218 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Baseline \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 2 (66.7%) \cell -\pard\intbl\qc\fs18 3 (100.0%) \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 13 (50.0%) \cell -\pard\intbl\qc\fs18 94 (95.9%) \cell -\pard\intbl\qc\fs18 9 (17.6%) \cell -\pard\intbl\qc\fs18 125 (100.0%) \cell +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5908 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9305 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 47 (71.2%) \cell +\pard\intbl\qc\fs18 50 (100.0%) \cell +\pard\intbl\qc\fs18 98 (100.0%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3977 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5105 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7479 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8725 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9971 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11218 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Week 2 \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell -\pard\intbl\qc\fs18 1 (33.3%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2806 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5908 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9305 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 09 \cell +\pard\intbl\qc\fs18 38 (57.6%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 3 (37.5%) \cell -\pard\intbl\qc\fs18 3 (11.5%) \cell -\pard\intbl\qc\fs18 2 (2.0%) \cell -\pard\intbl\qc\fs18 41 (80.4%) \cell -\pard\intbl\qc\fs18 104 (83.2%) \cell +\pard\intbl\qc\fs18 39 (39.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2849 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3977 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5105 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6351 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7479 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8725 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9971 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11218 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Week 24 \cell -\pard\intbl\qc\fs18 2 (66.7%) \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (25.0%) \cell -\pard\intbl\qc\fs18 12 (46.2%) \cell -\pard\intbl\qc\fs18 17 (17.3%) \cell -\pard\intbl\qc\fs18 2 (3.9%) \cell -\pard\intbl\qc\fs18 35 (28.0%) \cell -\row -} - -{ -\trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2849 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx3977 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5105 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6351 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7479 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8725 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9971 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx11218 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2806 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5908 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9305 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell -\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2849 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx3977 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5105 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6351 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7479 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8725 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9971 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx11218 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2806 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5908 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9305 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell \pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell -\pard\intbl\qc \cell \row } diff --git a/tests/testthat/_snaps/tsiex09/tsiex09.rtf b/tests/testthat/_snaps/tsiex09/tsiex09.rtf old mode 100755 new mode 100644 index 4d0ef781..373e0c99 --- a/tests/testthat/_snaps/tsiex09/tsiex09.rtf +++ b/tests/testthat/_snaps/tsiex09/tsiex09.rtf @@ -36,8 +36,8 @@ \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Study Treatment \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row @@ -50,10 +50,10 @@ \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Lot, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } @@ -78,9 +78,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 XXX-YYY-ZZZ-002 \cell -\pard\intbl\qc\fs18 30 (56.6%) \cell -\pard\intbl\qc\fs18 31 (42.5%) \cell -\pard\intbl\qc\fs18 61 (48.4%) \cell +\pard\intbl\qc\fs18 29 (43.3%) \cell +\pard\intbl\qc\fs18 27 (52.9%) \cell +\pard\intbl\qc\fs18 56 (47.5%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -92,9 +92,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 XXX-YYY-ZZZ-003 \cell -\pard\intbl\qc\fs18 26 (49.1%) \cell -\pard\intbl\qc\fs18 28 (38.4%) \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell +\pard\intbl\qc\fs18 24 (35.8%) \cell +\pard\intbl\qc\fs18 28 (54.9%) \cell +\pard\intbl\qc\fs18 52 (44.1%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -106,9 +106,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 XXX-YYY-ZZZ-004 \cell -\pard\intbl\qc\fs18 20 (37.7%) \cell -\pard\intbl\qc\fs18 38 (52.1%) \cell -\pard\intbl\qc\fs18 58 (46.0%) \cell +\pard\intbl\qc\fs18 37 (55.2%) \cell +\pard\intbl\qc\fs18 25 (49.0%) \cell +\pard\intbl\qc\fs18 62 (52.5%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -120,9 +120,9 @@ \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 XXX-YYY-ZZZ-005 \cell -\pard\intbl\qc\fs18 25 (47.2%) \cell -\pard\intbl\qc\fs18 29 (39.7%) \cell -\pard\intbl\qc\fs18 54 (42.9%) \cell +\pard\intbl\qc\fs18 30 (44.8%) \cell +\pard\intbl\qc\fs18 21 (41.2%) \cell +\pard\intbl\qc\fs18 51 (43.2%) \cell \pard\intbl\qc\fs18 0 \cell \row } @@ -165,7 +165,7 @@ \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 32 (54.2%) \cell +\pard\intbl\qc\fs18 36 (56.3%) \cell \row } @@ -179,7 +179,7 @@ \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 28 (47.5%) \cell +\pard\intbl\qc\fs18 31 (48.4%) \cell \row } @@ -193,7 +193,7 @@ \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 33 (55.9%) \cell +\pard\intbl\qc\fs18 35 (54.7%) \cell \row } @@ -207,7 +207,7 @@ \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 32 (54.2%) \cell +\pard\intbl\qc\fs18 32 (50.0%) \cell \row } diff --git a/tests/testthat/_snaps/tsiex10/tsiex10.rtf b/tests/testthat/_snaps/tsiex10/tsiex10.rtf old mode 100755 new mode 100644 index c4be2490..17898d7f --- a/tests/testthat/_snaps/tsiex10/tsiex10.rtf +++ b/tests/testthat/_snaps/tsiex10/tsiex10.rtf @@ -3,10 +3,10 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2881 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7612 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2868 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4449 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6029 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7609 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX10:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -17,10 +17,10 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2881 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7612 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2868 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4449 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6029 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7609 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -31,13 +31,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Combined \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \row @@ -45,24 +45,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7612 +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Parameter \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=53 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=73 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=126 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=59 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Compliance (%)\super a\nosupersub \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -73,66 +73,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 N \cell -\pard\intbl\qc\fs18 53 \cell -\pard\intbl\qc\fs18 73 \cell -\pard\intbl\qc\fs18 126 \cell -\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 67 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 118 \cell +\pard\intbl\qc\fs18 64 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Mean (SD) \cell -\pard\intbl\qc\fs18 63.7 (35.23) \cell -\pard\intbl\qc\fs18 66.5 (38.42) \cell -\pard\intbl\qc\fs18 65.3 (36.99) \cell -\pard\intbl\qc\fs18 57.0 (36.23) \cell +\pard\intbl\qc\fs18 62.13 (35.984) \cell +\pard\intbl\qc\fs18 72.43 (32.226) \cell +\pard\intbl\qc\fs18 66.58 (34.648) \cell +\pard\intbl\qc\fs18 64.39 (37.003) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Median \cell -\pard\intbl\qc\fs18 64.0 \cell -\pard\intbl\qc\fs18 70.0 \cell -\pard\intbl\qc\fs18 68.0 \cell -\pard\intbl\qc\fs18 50.0 \cell +\pard\intbl\qc\fs18 65.00 \cell +\pard\intbl\qc\fs18 67.00 \cell +\pard\intbl\qc\fs18 66.50 \cell +\pard\intbl\qc\fs18 66.50 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Min, max \cell -\pard\intbl\qc\fs18 0, 120 \cell -\pard\intbl\qc\fs18 1, 122 \cell -\pard\intbl\qc\fs18 0, 122 \cell -\pard\intbl\qc\fs18 1, 124 \cell +\pard\intbl\qc\fs18 0.0, 121.0 \cell +\pard\intbl\qc\fs18 9.0, 124.0 \cell +\pard\intbl\qc\fs18 0.0, 124.0 \cell +\pard\intbl\qc\fs18 4.0, 125.0 \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -143,11 +143,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Compliance category\super a\nosupersub , n (%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Compliance category\super a\nosupersub , n (%) \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -157,66 +157,66 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 <60% \cell -\pard\intbl\qc\fs18 22 (41.5%) \cell -\pard\intbl\qc\fs18 28 (38.4%) \cell -\pard\intbl\qc\fs18 50 (39.7%) \cell -\pard\intbl\qc\fs18 32 (54.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 <60% \cell +\pard\intbl\qc\fs18 31 (46.3%) \cell +\pard\intbl\qc\fs18 19 (37.3%) \cell +\pard\intbl\qc\fs18 50 (42.4%) \cell +\pard\intbl\qc\fs18 29 (45.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 60% to <80% \cell -\pard\intbl\qc\fs18 11 (20.8%) \cell -\pard\intbl\qc\fs18 13 (17.8%) \cell -\pard\intbl\qc\fs18 24 (19.0%) \cell -\pard\intbl\qc\fs18 9 (15.3%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 60% to <80% \cell +\pard\intbl\qc\fs18 9 (13.4%) \cell +\pard\intbl\qc\fs18 7 (13.7%) \cell +\pard\intbl\qc\fs18 16 (13.6%) \cell +\pard\intbl\qc\fs18 9 (14.1%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 80% to <100% \cell -\pard\intbl\qc\fs18 8 (15.1%) \cell -\pard\intbl\qc\fs18 14 (19.2%) \cell -\pard\intbl\qc\fs18 22 (17.5%) \cell -\pard\intbl\qc\fs18 8 (13.6%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 80% to <100% \cell +\pard\intbl\qc\fs18 13 (19.4%) \cell +\pard\intbl\qc\fs18 13 (25.5%) \cell +\pard\intbl\qc\fs18 26 (22.0%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2881 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4458 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6035 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7612 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 \u8805?100% \cell -\pard\intbl\qc\fs18 12 (22.6%) \cell -\pard\intbl\qc\fs18 18 (24.7%) \cell -\pard\intbl\qc\fs18 30 (23.8%) \cell -\pard\intbl\qc\fs18 10 (16.9%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2868 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4449 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6029 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7609 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 \u8805?100% \cell +\pard\intbl\qc\fs18 14 (20.9%) \cell +\pard\intbl\qc\fs18 12 (23.5%) \cell +\pard\intbl\qc\fs18 26 (22.0%) \cell +\pard\intbl\qc\fs18 13 (20.3%) \cell \row } { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2881 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7612 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2868 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4449 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6029 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7609 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -227,10 +227,10 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2881 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4458 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6035 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7612 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2868 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4449 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6029 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7609 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/_snaps/tsiex12/tsiex12.rtf b/tests/testthat/_snaps/tsiex12/tsiex12.rtf new file mode 100644 index 00000000..a28b95d0 --- /dev/null +++ b/tests/testthat/_snaps/tsiex12/tsiex12.rtf @@ -0,0 +1,564 @@ +{\rtf1\ansi\deff0\portrait\paperw12240\paperh15840\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIEX12:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2863 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr Time Point \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clmgf\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Dose Modification \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 System Organ Class \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li630\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Overall \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose not administered \cell +\pard\intbl\qc\fs18 29 (61.7%) \cell +\pard\intbl\qc\fs18 30 (58.8%) \cell +\pard\intbl\qc\fs18 59 (60.2%) \cell +\pard\intbl\qc\fs18 44 (72.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Nausea \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose adjusted \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Investigations \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Thrombocytopenia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Nausea \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 98 \cell +\pard\intbl\qc\fs18 61 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose not administered \cell +\pard\intbl\qc\fs18 25 (53.2%) \cell +\pard\intbl\qc\fs18 23 (45.1%) \cell +\pard\intbl\qc\fs18 48 (49.0%) \cell +\pard\intbl\qc\fs18 31 (50.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Nausea \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose adjusted \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Nausea \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (2.0%) \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cycle 09 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 40 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose not administered \cell +\pard\intbl\qc\fs18 7 (36.8%) \cell +\pard\intbl\qc\fs18 10 (50.0%) \cell +\pard\intbl\qc\fs18 17 (43.6%) \cell +\pard\intbl\qc\fs18 23 (57.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dose adjusted \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li447\fi-87 Adverse event \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Fatigue \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Investigations \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li807\fi-87 Thrombocytopenia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (5.0%) \cell +\pard\intbl\qc\fs18 1 (2.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2863 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4444 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6026 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7608 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file diff --git a/tests/testthat/_snaps/tsimh01/tsimh01.rtf b/tests/testthat/_snaps/tsimh01/tsimh01.rtf old mode 100755 new mode 100644 index f4f27d65..69727003 --- a/tests/testthat/_snaps/tsimh01/tsimh01.rtf +++ b/tests/testthat/_snaps/tsimh01/tsimh01.rtf @@ -3,10 +3,10 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2878 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4456 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6034 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7611 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2867 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4411 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5955 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7499 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSIMH01:\tab Dummy Title\b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell \pard\intbl\ql\fs20 \b \b0 \cell @@ -17,10 +17,10 @@ { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2878 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4456 -\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6034 -\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7611 +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2867 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4411 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5955 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx7499 \clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell \pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell @@ -31,13 +31,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr System Organ Class \cell -\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell \pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell \pard\intbl\qc\fs18 \keepn\trhdr Total \cell \row @@ -45,38 +45,2586 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=84 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=84 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=86 \cell -\pard\intbl\qc\fs18 \keepn\trhdr N=254 \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Preferred Term, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=96 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=72 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=86 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=254 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 medical history \cell +\pard\intbl\qc\fs18 67 (69.8%) \cell +\pard\intbl\qc\fs18 53 (73.6%) \cell +\pard\intbl\qc\fs18 57 (66.3%) \cell +\pard\intbl\qc\fs18 177 (69.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Uncoded \cell +\pard\intbl\qc\fs18 19 (19.8%) \cell +\pard\intbl\qc\fs18 19 (26.4%) \cell +\pard\intbl\qc\fs18 13 (15.1%) \cell +\pard\intbl\qc\fs18 51 (20.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Uncoded: Alzheimer's disease \cell +\pard\intbl\qc\fs18 19 (19.8%) \cell +\pard\intbl\qc\fs18 19 (26.4%) \cell +\pard\intbl\qc\fs18 13 (15.1%) \cell +\pard\intbl\qc\fs18 51 (20.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Surgical and medical procedures \cell +\pard\intbl\qc\fs18 16 (16.7%) \cell +\pard\intbl\qc\fs18 21 (29.2%) \cell +\pard\intbl\qc\fs18 12 (14.0%) \cell +\pard\intbl\qc\fs18 49 (19.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Appendicectomy \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 5 (6.9%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 7 (2.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hysterectomy \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 6 (2.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Tonsillectomy \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 6 (2.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hernia repair \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 5 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cataract operation \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cholecystectomy \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Gastric ulcer surgery \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Transurethral prostatectomy \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Brain operation \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Caesarean section \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Carotid endarterectomy \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Chemotherapy \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Colectomy \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Ear operation \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Face lift \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Haemorrhoid operation \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hip arthroplasty \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Inguinal hernia repair \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Intestinal adhesion lysis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Knee arthroplasty \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Mastectomy \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oophorectomy partial \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Prostatectomy \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus operation \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin graft \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin lesion excision \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Surgery \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Thyroid operation \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Tumour excision \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Umbilical hernia repair \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Wisdom teeth removal \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Musculoskeletal and connective tissue disorders \cell +\pard\intbl\qc\fs18 10 (10.4%) \cell +\pard\intbl\qc\fs18 11 (15.3%) \cell +\pard\intbl\qc\fs18 8 (9.3%) \cell +\pard\intbl\qc\fs18 29 (11.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthritis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 8 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Osteoarthritis \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Polyarthritis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Back pain \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Arthralgia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dupuytren's contracture \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Ganglion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Intervertebral disc protrusion \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Monarthritis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Muscle spasms \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Osteoporosis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pain in extremity \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rheumatic fever \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rheumatoid arthritis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Shoulder pain \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Spinal column stenosis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Spondylitis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Gastrointestinal disorders \cell +\pard\intbl\qc\fs18 10 (10.4%) \cell +\pard\intbl\qc\fs18 7 (9.7%) \cell +\pard\intbl\qc\fs18 11 (12.8%) \cell +\pard\intbl\qc\fs18 28 (11.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Constipation \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 4 (4.7%) \cell +\pard\intbl\qc\fs18 8 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diverticulum \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dyspepsia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Gastric ulcer \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Gastrooesophageal reflux disease \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Inguinal hernia \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rectal haemorrhage \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal adhesions \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal discomfort \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abdominal hernia \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diarrhoea \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Duodenal ulcer \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Gastrointestinal pain \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hiatus hernia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oesophageal spasm \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oesophageal stenosis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Painful defaecation \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Ear and labyrinth disorders \cell +\pard\intbl\qc\fs18 6 (6.3%) \cell +\pard\intbl\qc\fs18 5 (6.9%) \cell +\pard\intbl\qc\fs18 5 (5.8%) \cell +\pard\intbl\qc\fs18 16 (6.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoacusis \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 6 (2.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Deafness \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Deafness bilateral \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cerumen impaction \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Ear pain \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Meniere's disease \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Tinnitus \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Cardiac disorders \cell +\pard\intbl\qc\fs18 7 (7.3%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 14 (5.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial infarction \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 5 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Bradycardia \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Bundle branch block right \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Angina pectoris \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial hypertrophy \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Atrial tachycardia \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Coronary artery disease \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Myocardial ischaemia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Eye disorders \cell +\pard\intbl\qc\fs18 5 (5.2%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 5 (5.8%) \cell +\pard\intbl\qc\fs18 14 (5.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Glaucoma \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 5 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cataract \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Presbyopia \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Blindness unilateral \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Conjunctival discolouration \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dry eye \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypermetropia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Macular degeneration \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Retinal detachment \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Infections and infestations \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 5 (6.9%) \cell +\pard\intbl\qc\fs18 6 (7.0%) \cell +\pard\intbl\qc\fs18 14 (5.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinusitis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pneumonia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cellulitis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Gonorrhoea \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Groin abscess \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Herpes zoster \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hordeolum \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Onychomycosis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Rhinitis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Tuberculosis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper respiratory tract infection \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Nervous system disorders \cell +\pard\intbl\qc\fs18 4 (4.2%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 6 (7.0%) \cell +\pard\intbl\qc\fs18 14 (5.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dizziness \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Headache \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cervicobrachial syndrome \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Convulsion \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diabetic neuropathy \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypoaesthesia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Neuralgia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Paraesthesia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Syncope \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Vascular disorders \cell +\pard\intbl\qc\fs18 4 (4.2%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 4 (4.7%) \cell +\pard\intbl\qc\fs18 12 (4.7%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypertension \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 4 (4.7%) \cell +\pard\intbl\qc\fs18 10 (3.9%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Aortic stenosis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Venous insufficiency \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 General disorders and administration site conditions \cell +\pard\intbl\qc\fs18 6 (6.3%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 11 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema peripheral \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Oedema \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Chest pain \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cyst \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Ulcer \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Metabolism and nutrition disorders \cell +\pard\intbl\qc\fs18 4 (4.2%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 5 (5.8%) \cell +\pard\intbl\qc\fs18 11 (4.3%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypercholesterolaemia \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 3 (3.5%) \cell +\pard\intbl\qc\fs18 5 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diabetes mellitus \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Diabetes mellitus non-insulin-dependent \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Gout \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hyperlipidaemia \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Investigations \cell +\pard\intbl\qc\fs18 4 (4.2%) \cell +\pard\intbl\qc\fs18 4 (5.6%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 9 (3.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cardiac murmur \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Biopsy prostate normal \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Biopsy breast normal \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Catheterisation cardiac \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Electrocardiogram st segment elevation \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Prostatic specific antigen increased \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Neoplasms benign, malignant and unspecified (incl cysts and polyps) \cell +\pard\intbl\qc\fs18 4 (4.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (5.8%) \cell +\pard\intbl\qc\fs18 9 (3.5%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Basal cell carcinoma \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Breast cancer \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Lipoma \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Prostate cancer \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Meningioma \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Injury, poisoning and procedural complications \cell +\pard\intbl\qc\fs18 3 (3.1%) \cell +\pard\intbl\qc\fs18 3 (4.2%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 8 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Fall \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Foot fracture \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hand fracture \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Limb injury \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Skin laceration \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Upper limb fracture \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Whiplash injury \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Wrist fracture \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Renal and urinary disorders \cell +\pard\intbl\qc\fs18 8 (8.3%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 8 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Incontinence \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nephrolithiasis \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dysuria \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Enuresis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell \row } { \trowd -\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Subjects with \u8805?1 ongoing medical history \cell -\pard\intbl\qc\fs18 5 (6.0%) \cell -\pard\intbl\qc\fs18 2 (2.4%) \cell -\pard\intbl\qc\fs18 6 (7.0%) \cell -\pard\intbl\qc\fs18 13 (5.1%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Micturition urgency \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nocturia \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pollakiuria \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Urinary incontinence \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -87,25 +2635,67 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 SURGICAL AND MEDICAL PROCEDURES \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell -\pard\intbl\qc\fs18 2 (2.4%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Respiratory, thoracic and mediastinal disorders \cell +\pard\intbl\qc\fs18 4 (4.2%) \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell \pard\intbl\qc\fs18 2 (2.3%) \cell -\pard\intbl\qc\fs18 5 (2.0%) \cell +\pard\intbl\qc\fs18 8 (3.1%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cough \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Asthma \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Chronic obstructive pulmonary disease \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CATARACT OPERATION \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Emphysema \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (1.2%) \cell @@ -115,12 +2705,96 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HERNIA REPAIR \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pharyngolaryngeal pain \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pulmonary fibrosis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Sinus polyp \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Skin and subcutaneous tissue disorders \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 4 (4.7%) \cell +\pard\intbl\qc\fs18 7 (2.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Actinic keratosis \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Dry skin \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.4%) \cell @@ -129,11 +2803,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HIP ARTHROPLASTY \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Nail discolouration \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (1.2%) \cell @@ -143,13 +2817,83 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 INTERVERTEBRAL DISC OPERATION \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Psoriasis \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Seborrhoeic dermatitis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Reproductive system and breast disorders \cell +\pard\intbl\qc\fs18 5 (5.2%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 5 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Benign prostatic hyperplasia \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (0.8%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Breast cyst \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.4%) \cell \row @@ -157,13 +2901,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 TOOTH EXTRACTION \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Erectile dysfunction \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.4%) \cell \row @@ -171,10 +2915,24 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Prostatitis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -185,66 +2943,220 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 INJURY, POISONING AND PROCEDURAL COMPLICATIONS \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Social circumstances \cell +\pard\intbl\qc\fs18 2 (2.1%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 5 (2.0%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Denture wearer \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 3 (1.2%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Menopause \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.2%) \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Walking aid user \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Endocrine disorders \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hypothyroidism \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 2 (2.3%) \cell +\pard\intbl\qc\fs18 4 (1.6%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Congenital, familial and genetic disorders \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 2 (2.8%) \cell +\pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 2 (0.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 SKIN LACERATION \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Pigmented naevus \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Ventricular septal defect \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell +\pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (0.4%) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hepatobiliary disorders \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 2 (2.3%) \cell \pard\intbl\qc\fs18 2 (0.8%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 CONTUSION \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cholelithiasis \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell \pard\intbl\qc\fs18 1 (0.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 PAIN TRAUMA ACTIVATED \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Hepatitis \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 0 \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell \pard\intbl\qc\fs18 1 (0.4%) \cell \row } { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -255,13 +3167,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 METABOLISM AND NUTRITION DISORDERS \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Psychiatric disorders \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 1 (1.2%) \cell \pard\intbl\qc\fs18 2 (0.8%) \cell \row @@ -269,11 +3181,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 HYPERCHOLESTEROLAEMIA \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Confusional state \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (1.2%) \cell @@ -283,13 +3195,13 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 VITAMIN B12 DEFICIENCY \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Tic \cell \pard\intbl\qc\fs18 0 \cell +\pard\intbl\qc\fs18 1 (1.4%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.4%) \cell \row @@ -297,10 +3209,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -311,11 +3223,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 INFECTIONS AND INFESTATIONS \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Immune system disorders \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (1.2%) \cell @@ -325,11 +3237,11 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 NASOPHARYNGITIS \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Seasonal allergy \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (1.2%) \cell @@ -339,10 +3251,10 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell \pard\intbl\qc\fs18 \cell \pard\intbl\qc\fs18 \cell @@ -353,12 +3265,12 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 INVESTIGATIONS \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Pregnancy, puerperium and perinatal conditions \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.4%) \cell @@ -367,12 +3279,12 @@ { \trowd -\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2878 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4456 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6034 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7611 -\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 BLOOD PRESSURE INCREASED \cell -\pard\intbl\qc\fs18 1 (1.2%) \cell +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2867 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4411 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5955 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7499 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Abortion \cell +\pard\intbl\qc\fs18 1 (1.0%) \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 0 \cell \pard\intbl\qc\fs18 1 (0.4%) \cell @@ -381,10 +3293,10 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2878 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4456 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6034 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7611 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2867 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4411 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5955 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx7499 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell \pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell @@ -395,10 +3307,10 @@ { \trowd -\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2878 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4456 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6034 -\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7611 +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2867 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4411 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5955 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx7499 \clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx9189 \pard\intbl\ql\fs16 \cell \pard\intbl\qc \cell \pard\intbl\qc \cell diff --git a/tests/testthat/setup-jnj.R b/tests/testthat/setup-jnj.R index b4a937da..e67b5e64 100644 --- a/tests/testthat/setup-jnj.R +++ b/tests/testthat/setup-jnj.R @@ -25,9 +25,14 @@ adlb_jnj <- pharmaverseadamjnj::adlb advs_jnj <- pharmaverseadamjnj::advs adttesaf_jnj <- pharmaverseadamjnj::adttesaf adaeocmq_jnj <- pharmaverseadamjnj::adaeocmq - +adagocmq_jnj <- pharmaverseadamjnj::adagocmq adpc_jnj <- pharmaverseadamjnj::adpc +addili_jnj <- pharmaverseadamjnj::addili +adishum_jnj <- pharmaverseadamjnj::adishum +addisp_jnj <- pharmaverseadamjnj::addisp ## pharmaversesdtmjnj ------------------------------- ds_jnj <- pharmaversesdtmjnj::ds mh_jnj <- pharmaversesdtmjnj::mh +dv_jnj <- pharmaversesdtmjnj::dv +ie_jnj <- pharmaversesdtmjnj::ie diff --git a/tests/testthat/source_code/lbtoxgrade.xlsx b/tests/testthat/source_code/lbtoxgrade.xlsx index 311e566f..2e24470d 100644 Binary files a/tests/testthat/source_code/lbtoxgrade.xlsx and b/tests/testthat/source_code/lbtoxgrade.xlsx differ diff --git a/tests/testthat/source_code/lirada01.R b/tests/testthat/source_code/lirada01.R new file mode 100644 index 00000000..5b16ca75 --- /dev/null +++ b/tests/testthat/source_code/lirada01.R @@ -0,0 +1,257 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LIRADA01" +fileid <- write_path(opath, tblid) +popfl <- "IMFL" # Immunogenicity Analysis Set flag +trtvar <- "TRT01A" +trtvarnum <- "TRT01AN" +adpc_paramcd_criteria <- "DOSE" +parqual_value <- "XANOMELINE" +sev_grade_fl <- "AESEV" # set to "AETOXGR" for toxicity grade +# sev_grade_fl <- "AETOXGR" +# ADAE AESCAT filter — user updates list as needed +ae_scat_values <- c( + "Infusion related reaction", + "Infusion site reaction", + "Injection site reaction" +) + +key_cols <- c("COL0", "COL1", "COL2") +sort_cols <- c(trtvarnum, "COL1", "AVISITN") +disp_cols <- paste0("COL", 0:9) +study_specific_col <- c( + "COL9", + "COL10" +) + +study_agent <- "active study agent" +agent_antibody_label <- sprintf("antibodies to %s", study_agent) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +############################################################################### +# Process data +############################################################################### + +# Read adishum with population and PARQUAL filters +adishum <- adishum_jnj |> + filter( + !!rlang::sym(popfl) == "Y", + toupper(PARQUAL) == toupper(parqual_value) + ) + +# top level filter — ADA-positive subjects +main_subject_list <- adishum |> + filter( + toupper(PARAMCD) == "ADATRE", + toupper(AVALC) == "Y" + ) |> + pull(USUBJID) |> + unique() + +# Read all adex records for ADA-positive subjects +adex <- adex_jnj |> + filter(USUBJID %in% main_subject_list) |> + select(USUBJID, AVISIT, EXSTDT, AOCCUR) + +# Read adae filtered by AESCAT and ADA-positive subjects +adae <- adae_jnj |> + filter( + USUBJID %in% main_subject_list, + toupper(AESCAT) %in% toupper(ae_scat_values) + ) |> + select( + USUBJID, + DOSEDT, + AESER, + AESEV, + AESEVN, + AETOXGR, + AETOXGRN + ) |> + mutate(react_flg = "Y") + +# Derive per-subject flags from ADAE records linked to ADEX via USUBJID + date +# DOSEDT is SAS numeric date (double); SAS origin is 1960-01-01 +adae_linked <- adae |> + mutate( + DOSEDT = as.Date(DOSEDT, origin = "1960-01-01") + ) |> + inner_join( + adex |> + select(USUBJID, EXSTDT, AVISIT), + by = c("USUBJID", "DOSEDT" = "EXSTDT") + ) + +# ADEX visit-level AOCCUR — join to lsting by USUBJID + AVISIT +adex_visit <- adex |> + select(USUBJID, AVISIT, AOCCUR) + +# One row per subject+visit — reaction flag Y if any linked AE exists +react_flg_df <- adae_linked |> + distinct(USUBJID, AVISIT, react_flg) + +# One row per subject+visit — AESER=Y if any linked AE is serious +aeser_flg_df <- adae_linked |> + group_by(USUBJID, AVISIT) |> + summarise( + aeser_flg = if_else(any(toupper(AESER) == "Y"), "Y", "N"), + .groups = "drop" + ) + +# One row per subject+visit — max severity label from linked AEs +# uses AESEV when sev_grade_fl = "AESEV", else AETOXGR +aesev_flg_df <- adae_linked |> + group_by(USUBJID) |> + summarise( + max_sev_flg = if (sev_grade_fl == "AESEV") { + AESEV[which.max(AESEVN)] + } else { + AETOXGR[which.max(AETOXGRN)] + }, + .groups = "drop" + ) + +# Read adpc PK concentration for ADA-positive subjects +adpc <- adpc_jnj |> + filter( + toupper(PARAMCD) == toupper(adpc_paramcd_criteria), + USUBJID %in% main_subject_list + ) |> + select( + USUBJID, + adpc_AVISIT = AVISIT, + adpc_AVAL = AVAL + ) + +adishum_filtered_titer <- adishum |> + filter( + toupper(PARAMCD) == "TITER", + USUBJID %in% main_subject_list + ) |> + select( + !!trtvar, + !!trtvarnum, + AVISIT, + AVISIT, + AVISITN, + USUBJID, + TITER_AVAL = AVAL + ) + +# Section --- Build Dataset Base From Adishum ------------ +# collect data after all joins; adex/react_fl_df/aeser_df/aesev_df are +# one row per subject — no many-to-many risk +lsting <- adishum_filtered_titer |> + left_join( + adpc, + by = c("USUBJID", "AVISIT" = "adpc_AVISIT") + ) |> + left_join(adex_visit, by = c("USUBJID", "AVISIT")) |> + left_join(react_flg_df, by = c("USUBJID", "AVISIT")) |> + left_join(aeser_flg_df, by = c("USUBJID", "AVISIT")) |> + left_join(aesev_flg_df, by = "USUBJID") + +# create necessary columns for Listing +lsting <- lsting |> + mutate( + COL0 = explicit_na(.data[[trtvar]]), + COL1 = explicit_na(USUBJID, ""), + COL2 = explicit_na(AVISIT, ""), + # STUDY-SPECIFIC: update to Injection, Infusion, or Dose as appropriate + COL3 = explicit_na(AOCCUR, ""), + # Optional Column: COL4/react_flg + COL4 = if_else(!is.na(react_flg), react_flg, ""), + # Optional Column: COL5/aeser_flg + COL5 = if_else(!is.na(aeser_flg), aeser_flg, ""), + # Optional Column: COL6/max_sev_flg + COL6 = if_else(!is.na(max_sev_flg), max_sev_flg, ""), + COL7 = if_else( + is.na(adpc_AVAL), + "", + formatC(adpc_AVAL, format = "fg") + ), + COL8 = if_else( + is.na(TITER_AVAL), + "", + formatC(TITER_AVAL, format = "fg") + ) # , + # STUDY-SPECIFIC: replace later + # COL9 = "STUDY-SPECIFIC", + # COL10 = "STUDY-SPECIFIC" + ) + +# define column names for listing +lsting <- var_relabel( + lsting, + COL0 = "Treatment Group", + COL1 = "Subject ID", + COL2 = "Visit", + # STUDY-SPECIFIC: update label to Injection, Infusion, or Dose as appropriate + COL3 = "[Injection / Infusion / Dose] Given?", + # Optional Column: COL4/react_flg + COL4 = "[Injection Site / Infusion-related] Reaction", + # Optional Column: COL5/aeser_flg + COL5 = "Serious", + # Optional Column: COL6/max_sev_flg + COL6 = "Maximum Severity", + COL7 = sprintf( + "Matrix %s Conc. (mcg/mL)", + stringi::stri_trans_totitle(study_agent) + ), + COL8 = sprintf( + "%s Status/Titer", + stringi::stri_trans_totitle(agent_antibody_label) + ) # , + # STUDY-SPECIFIC: update label to Success Criteria, Continuous Response, or Concomitant Medications + # COL9 = "[Success Criteria / Continuous Response]" + # COL10 = "[Success Criteria / Concomitant Medications]" +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols[!disp_cols %in% study_specific_col], + sort_cols = sort_cols, + round_type = "sas", + col_formatting = list( + COL7 = fmt_config( + na_str = "", + align = "right" + ), + COL8 = fmt_config( + na_str = "", + align = "right" + ) + ) +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(21, 63, 59, 23, 27, 13, 18, 23, 30) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lirada02.R b/tests/testthat/source_code/lirada02.R new file mode 100644 index 00000000..822933dc --- /dev/null +++ b/tests/testthat/source_code/lirada02.R @@ -0,0 +1,182 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LIRADA02" +fileid <- write_path(opath, tblid) +popfl <- "IMFL" # Immunogenicity Analysis Set flag +trtvar <- "TRT01A" +trtvarnum <- "TRT01AN" +adpc_paramcd_criteria <- "DOSE" + +key_cols <- c("COL0", "COL1", "COL2") +sort_cols <- c(trtvarnum, "COL1", "AVISITN") +disp_cols <- paste0("COL", 0:8) +study_specific_col <- c( + "COL7", + "COL8" +) + +study_agent <- "active study agent" +antibody_study_agent <- sprintf("antibodies to %s", study_agent) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +############################################################################### +# Process data +############################################################################### + +adishum <- adishum_jnj + +# top level filter +main_subject_list <- adishum |> + filter( + !!rlang::sym(popfl) == "Y" + ) |> + pull( + USUBJID + ) |> + unique() + +# dataset adpc +adpc <- adpc_jnj |> + filter( + toupper(PARAMCD) == toupper(adpc_paramcd_criteria), + USUBJID %in% main_subject_list + ) |> + select( + USUBJID, + adpc_AVISIT = AVISIT, + adpc_AVAL = AVAL + ) + +# dataset adae +adsl <- adsl_jnj |> + filter( + !is.na(DCSREAS), + USUBJID %in% main_subject_list + ) |> + select( + USUBJID, + DCSREAS + ) + +adishum_filtered_titer <- adishum |> + filter( + toupper(PARAMCD) == "TITER", + USUBJID %in% main_subject_list + ) |> + select( + !!trtvar, + !!trtvarnum, + AVISIT, + AVISITN, + USUBJID, + TRTA, + TITER_AVAL = AVAL + ) + +# Section --- Build Dataset Base From Adishum ------------ +# collect data after all joins +lsting <- adsl |> + left_join( + adishum_filtered_titer, + by = "USUBJID" + ) |> + left_join( + adpc, + by = c( + USUBJID = "USUBJID", + AVISIT = "adpc_AVISIT" + ) + ) + +# create necessary columns for Listing +lsting <- lsting |> + mutate( + COL0 = explicit_na(.data[[trtvar]]), + COL1 = explicit_na(USUBJID, ""), + COL2 = explicit_na(AVISIT, ""), + COL3 = explicit_na(DCSREAS, ""), + COL4 = explicit_na(TRTA, ""), + COL5 = if_else( + is.na(adpc_AVAL), + "", + formatC(adpc_AVAL, format = "fg") + ), + COL6 = if_else( + is.na(TITER_AVAL), + "", + formatC(TITER_AVAL, format = "fg") + ) # , + # STUDY-SPECIFIC: replace later + # COL7 = "STUDY-SPECIFIC", + # COL8 = "STUDY-SPECIFIC" + ) + +# define column names for listing +lsting <- var_relabel( + lsting, + COL0 = "Treatment Group", + COL1 = "Subject ID", + COL2 = "Visit", + COL3 = "Reason for Discontinuation", + COL4 = "Last Scheduled Study Treatment", + COL5 = sprintf( + "Matrix %s Conc. (mcg/mL)", + stringi::stri_trans_totitle(study_agent) + ), + COL6 = sprintf( + "%s Status/Titer", + stringi::stri_trans_totitle(antibody_study_agent) + ) + # STUDY-SPECIFIC: update label as appropriate + # COL7 = "[Success Criteria / Continuous Response]", + # COL8 = "[Concomitant Medication]" +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols[!disp_cols %in% study_specific_col], + sort_cols = sort_cols, + round_type = "sas", + col_formatting = list( + COL5 = fmt_config( + na_str = "", + align = "right" + ), + COL6 = fmt_config( + na_str = "", + align = "right" + ) + ) +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(21, 38, 59, 43, 71, 23, 30) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lirada03.R b/tests/testthat/source_code/lirada03.R new file mode 100644 index 00000000..63ee07fb --- /dev/null +++ b/tests/testthat/source_code/lirada03.R @@ -0,0 +1,138 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LIRADA03" +fileid <- write_path(opath, tblid) +popfl <- "IMFL" # Immunogenicity Analysis Set flag +trtvar <- "TRT01A" +trtvarnum <- "TRT01AN" +adpc_paramcd_criteria <- "XAN" # based on display ATPT criteria select values accordingly (if applicable) + +key_cols <- c("COL0", "COL1", "COL2") +sort_cols <- c(trtvarnum, "COL1", "AVISITN", "ATPTN") +disp_cols <- c("COL3", "COL4") + +study_agent <- "active study agent" +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +############################################################################### +# Process data +############################################################################### +adishum <- adishum_jnj + +# top level filter: subjects in the population +main_subject_list <- adishum |> + filter(!!rlang::sym(popfl) == "Y") |> + pull(USUBJID) |> + unique() + +# dataset adpc +adpc <- adpc_jnj |> + filter( + toupper(PARAMCD) == toupper(adpc_paramcd_criteria), + USUBJID %in% main_subject_list + ) |> + select( + USUBJID, + AVISIT, + AVISITN, + ATPTN, + ATPT, + AVAL + ) + +adishum_filtered <- adishum |> + filter(USUBJID %in% main_subject_list) |> + select( + !!trtvar, + !!trtvarnum, + USUBJID, + DTL + ) |> + unique() + +# Section --- Build Dataset Base From Adishum ------------ +# collect data after all joins, then apply cross-dataset filter + +lsting <- adpc |> + left_join( + adishum_filtered, + by = c( + USUBJID = "USUBJID" + ) + ) |> + filter(AVAL > DTL) + +# create necessary columns for Listing +lsting <- lsting |> + mutate( + COL0 = explicit_na(.data[[trtvar]]), + COL1 = explicit_na(USUBJID, ""), + COL2 = explicit_na(AVISIT, ""), + # Optional Column: COL3/ATPT + COL3 = explicit_na(ATPT, ""), + COL4 = if_else( + is.na(AVAL), + "", + formatC(AVAL, format = "fg") + ) + ) + +# define column names for listing +lsting <- var_relabel( + lsting, + COL0 = "Treatment Group", + COL1 = "Subject ID", + COL2 = "Visit", + # Optional Column: COL3/ATPT + COL3 = "Time Point", + COL4 = sprintf( + "Matrix %s \nConc. (mcg/mL)", + stringi::stri_trans_totitle(study_agent) + ) +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas", + col_formatting = list( + COL4 = fmt_config( + na_str = "", + align = "right" + ) + ) +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(71, 63, 59, 60, 26) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lirada04.R b/tests/testthat/source_code/lirada04.R new file mode 100644 index 00000000..38e291fb --- /dev/null +++ b/tests/testthat/source_code/lirada04.R @@ -0,0 +1,117 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LIRADA04" +fileid <- write_path(opath, tblid) +popfl <- "IMFL" # Immunogenicity Analysis Set flag +trtvar <- "TRT01A" +trtvarnum <- "TRT01AN" + +parqual_value <- "XANOMELINE" +key_cols <- c("COL0", "COL1") +sort_cols <- c(trtvarnum, "COL1", "ADT") +disp_cols <- "COL2" + +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +############################################################################### +# Process data +############################################################################### + +adishum <- adishum_jnj + +# top level filter +main_subject_list <- adishum |> + filter( + !!rlang::sym(popfl) == "Y", + PARQUAL == parqual_value, + PARAMCD == "ADABL", + AVALC == "Y" + ) |> + pull( + USUBJID + ) |> + unique() + +# adishum_filtered on ADABLT +adishum_filtered_adablt <- adishum |> + filter( + stringi::stri_trans_toupper(PARAMCD) == "ADABLT", + USUBJID %in% main_subject_list + ) |> + select( + !!trtvar, + !!trtvarnum, + ADT, + USUBJID, + ADABLT_AVAL = AVAL + ) + +# Section --- Build Dataset Base From Adishum ------------ +# collect data after all joins +lsting <- adishum_filtered_adablt + +# create necessary columns for Listing +lsting <- lsting |> + mutate( + COL0 = explicit_na(.data[[trtvar]]), + COL1 = explicit_na(USUBJID, ""), + COL2 = if_else( + is.na(ADABLT_AVAL), + "", + formatC(ADABLT_AVAL, format = "fg") + ) + ) + +# define column names for listing +lsting <- var_relabel( + lsting, + COL0 = "Treatment Group", + COL1 = "Subject ID", + COL2 = "Baseline Titer" +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas", + col_formatting = list( + COL2 = fmt_config( + na_str = "", + align = "right" + ) + ) +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(71, 63, 15) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lirada05.R b/tests/testthat/source_code/lirada05.R new file mode 100644 index 00000000..216e973e --- /dev/null +++ b/tests/testthat/source_code/lirada05.R @@ -0,0 +1,164 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LIRADA05" +fileid <- write_path(opath, tblid) +popfl <- "IMFL" # Immunogenicity Analysis Set flag +trtvar <- "TRT01A" +trtvarnum <- "TRT01AN" + +key_cols <- c("COL0", "COL1", "COL2", "COL3") +sort_cols <- c(trtvarnum, "COL1", "AVISITN", "ATPTN") +disp_cols <- paste0("COL", 4:7) + +study_agent <- "active study agent" +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +############################################################################### +# Process data +############################################################################### + +adishum <- adishum_jnj + +# top level filter +main_subject_list <- adishum |> + filter( + !!rlang::sym(popfl) == "Y" + ) |> + pull( + USUBJID + ) |> + unique() + +# base: visit-level, one row per subject-visit-timepoint +adishum_filtered_main <- adishum |> + filter( + USUBJID %in% main_subject_list, + !is.na(AVISIT) + ) |> + select( + !!trtvar, + !!trtvarnum, + AVISIT, + AVISITN, + USUBJID, + ATPT, + ATPTN, + ADA_STATUS = ADATRES, + NAB_STATUS = NABSTAT + ) |> + distinct() + +# adishum_filtered on titer +adishum_filtered_titer <- adishum |> + filter( + stringi::stri_trans_toupper(PARAMCD) == "TITER", + USUBJID %in% main_subject_list + ) |> + select( + USUBJID, + AVISIT, + TITER_AVAL = AVAL + ) + +# adishum_filtered on NABCNR +adishum_filtered_nabcnr <- adishum |> + filter( + stringi::stri_trans_toupper(PARAMCD) == "NABCNR", + USUBJID %in% main_subject_list + ) |> + select( + USUBJID, + AVISIT, + NABCNR_AVALC = AVALC + ) + +# Section --- Build Dataset Base From Adishum ------------ +# collect data after all joins +lsting <- adishum_filtered_main |> + left_join(adishum_filtered_titer, by = c("USUBJID", "AVISIT")) |> + left_join(adishum_filtered_nabcnr, by = c("USUBJID", "AVISIT")) + +# create necessary columns for Listing +lsting <- lsting |> + mutate( + COL0 = explicit_na(.data[[trtvar]]), + COL1 = explicit_na(USUBJID, ""), + COL2 = explicit_na(ADA_STATUS, ""), + # Optional Column: COL3/NAB_STATUS + COL3 = explicit_na(NAB_STATUS, ""), + COL4 = explicit_na(AVISIT, ""), + # Optional Column: COL5/ATPT + COL5 = explicit_na(ATPT, ""), + COL6 = if_else( + is.na(TITER_AVAL), + "", + formatC(TITER_AVAL, format = "fg") + ), + # Optional Column: COL7/NABCNR_AVALC + COL7 = explicit_na(NABCNR_AVALC, "") + ) + +# define column names for listing +lsting <- var_relabel( + lsting, + COL0 = "Treatment Group", + COL1 = "Subject ID", + COL2 = "Subject Status~[super a] for Treatment-Emergent ADA", + # Optional Column: COL3/NAB_STATUS + COL3 = "Subject Status for NAb", + COL4 = "Visit", + # Optional Column: COL5/ATPT + COL5 = "Time Point", + COL6 = sprintf( + "Antibody to %s Status/Titer", + study_agent + ), + # Optional Column: COL7/NABCNR_AVALC + COL7 = "Sample Status for NAb" +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas", + col_formatting = list( + COL6 = fmt_config( + na_str = "", + align = "right" + ) + ) +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(39, 38, 25, 21, 59, 60, 29, 14) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lpk01.R b/tests/testthat/source_code/lpk01.R new file mode 100644 index 00000000..ae8f0dd4 --- /dev/null +++ b/tests/testthat/source_code/lpk01.R @@ -0,0 +1,145 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) +library(haven) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LPK01" +fileid <- write_path(opath, tblid) +popfl <- "PKFL" +trtvar <- "TRT01A" +key_cols <- c("COL0", "COL1", "COL2") +sort_cols <- c("COL0", "COL1", "COL2") +disp_cols <- paste0("COL", 0:6) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +concat_sep <- " / " +paramcd <- "XAN" + +# Set to NULL to keep all records including derived (DTYPE) records +exclude_dtype <- TRUE + +############################################################################### +# Process data +############################################################################### + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + select(USUBJID, all_of(c(trtvar, popfl))) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + + +adpc <- adpc_jnj |> + filter(PARAMCD == paramcd, PKRFL == "N") |> + filter(if (!is.null(exclude_dtype) && exclude_dtype) is.na(DTYPE) else TRUE) |> + select( + STUDYID, + USUBJID, + PKRFL, + AVISIT, + AVISITN, + ADT, + ADTM, + ATPT, + ATPTN, + AVAL, + any_of(starts_with("CRIT")) + ) |> + inner_join(adsl, by = c("USUBJID")) + +lsting <- adpc |> + mutate( + COL0 = explicit_na(.data[[trtvar]], ""), + COL1 = explicit_na(USUBJID, ""), + COL2 = explicit_na(AVISIT, ""), + COL3 = ifelse( + !is.na(ADTM), + paste0( + toupper(format(as.Date(ADT), "%d%b%Y")), + concat_sep, + substr(as.character(ADTM), 12, 16) + ), + ifelse(!is.na(ADT), toupper(format(as.Date(ADT), "%d%b%Y")), "") + ), + # Time point is optional + COL4 = explicit_na(ATPT, ""), + COL5 = explicit_na(as.character(AVAL), ""), + # COL6: Concatenates exclusion reasons from CRIT* columns where CRIT*FL = "Y", separated by " ; " + COL6 = apply( + select(pick(everything()), matches("^CRIT[0-9]+FL$"), matches("^CRIT[0-9]+$")), + 1, + function(row) { + fl_vars <- names(row)[grepl("^CRIT[0-9]+FL$", names(row))] + val_vars <- names(row)[grepl("^CRIT[0-9]+$", names(row))] + vals <- sapply(fl_vars, function(fl) { + num <- gsub("CRIT|FL", "", fl) + val_var <- paste0("CRIT", num) + if (isTRUE(row[[fl]] == "Y") && val_var %in% val_vars) row[[val_var]] else NA_character_ + }) + res <- paste(na.omit(stringr::str_to_sentence(vals)), collapse = " ; ") + if (nchar(res) == 0) NA_character_ else res + } + ), + ) |> + arrange( + COL0, + COL1, + AVISITN, + ATPTN + ) + +lsting <- var_relabel( + lsting, + COL0 = "Treatment Group", + COL1 = "Subject ID", + COL2 = "Visit", + COL3 = paste("Sample Date", "Time", sep = concat_sep), + COL4 = "Time Point", + COL5 = "Matrix Active Study Agent Conc. (\u00b5g/mL)", + COL6 = "Reason for Exclusion" +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" +) + +############################################################################### +# Add titles and footnotes: +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +# [AUTO-COLWIDTH] + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfae01.R b/tests/testthat/source_code/lsfae01.R index 4dbe8dea..d290b2eb 100644 --- a/tests/testthat/source_code/lsfae01.R +++ b/tests/testthat/source_code/lsfae01.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfae01.R -## R version: 4.2.1 -## Short Description: Create LSFAE01: Listing of Treatment-emergent -## Adverse Events -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-19 -## Input: ADAE -## Output: lsfae01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: JJCS_TLGS_R -## Date: 2024-05-15 -## Description: Added option to display time in start and end dates -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -41,7 +15,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2") -disp_cols <- paste0("COL", 0:10) +sort_cols <- c("COL0", "COL1", "COL2") +disp_cols <- paste0("COL", 0:11) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -50,19 +25,192 @@ tab_titles <- list( ) # Parameter to control whether time should be displayed # from ASTDTM include_time <- TRUE +# Parameter to control whether imputed date to be displayed +include_imputed_dates <- FALSE + +# Combination treatment parameters + +# Provide whether this is a combination treatments +combination_trt <- FALSE + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc + comb_acnvars <- paste0("AEACNS", seq_len(n_comb_trt)) # This will create a variable list like AEACNS1, AEACNS2 etc + comb_dosvars <- paste0("DOSS", seq_len(n_comb_trt), "ON") # This will create a variable list like DOSS1ON, DOSS2ON etc + comb_dosuvars <- paste0("DOSS", seq_len(n_comb_trt), "U") # This will create a variable list like DOSS1U, DOSS2U etc + comb_dosdyvars <- paste0("DOSS", seq_len(n_comb_trt), "DY") # This will create a variable list like DOSS1DY, DOSS2DY etc +} + ############################################################################### # Process data ############################################################################### -adae <- adae_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & TRTEMFL == "Y") +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(!!rlang::sym(popfl) == "Y" & TRTEMFL == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + dplyr::case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male", + SEX == "U" ~ "Unknown", + SEX == "INTERSEX" ~ "Intersex" + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + AEOUT = factor( + case_when( + AEOUT == "FATAL" ~ "Fatal", + AEOUT == "NOT RECOVERED/NOT RESOLVED" ~ "Not Recovered/Not Resolved", + AEOUT == "RECOVERED/RESOLVED" ~ "Recovered/Resolved" + ), + levels = c( + "Fatal", + "Not Recovered/Not Resolved", + "Recovered/Resolved" + ) + ), + AESER = factor( + case_when( + AESER == "Y" ~ "Yes", + AESER == "N" ~ "No" + ), + levels = c( + "Yes", + "No" + ) + ), + AEREL = factor( + case_when( + AEREL == "NOT RELATED" ~ "Not Related", + AEREL == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ), + AEACN = factor( + case_when( + AEACN == "DOSE NOT CHANGED" ~ "Dose Not Changed", + AEACN == "NOT APPLICABLE" ~ "Not Applicable", + AEACN == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + AEACN == "DOSE REDUCED" ~ "Dose Reduced", + AEACN == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + AEACN == "DRUG INTERRUPTED" ~ "Drug Interrupted", + AEACN == "DOSE INCREASED" ~ "Dose Increased", + AEACN == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + +################################### +# Section for combination treatment +################################### -lsting <- adae %>% +if (combination_trt) { + adae <- adae |> + mutate( + across( + all_of(comb_relvars), + ~ factor( + case_when( + . == "NOT RELATED" ~ "Not Related", + . == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ) + ), + across( + all_of(comb_acnvars), + ~ factor( + case_when( + . == "DOSE NOT CHANGED" ~ "Dose Not Changed", + . == "NOT APPLICABLE" ~ "Not Applicable", + . == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + . == "DOSE REDUCED" ~ "Dose Reduced", + . == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + . == "DRUG INTERRUPTED" ~ "Drug Interrupted", + . == "DOSE INCREASED" ~ "Dose Increased", + . == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + ) +} + +################################### + +lsting <- adae |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), DOSEON = explicit_na(as.character(DOSEON), ""), DOSEU = explicit_na(DOSEU, ""), DOSEDY = explicit_na(as.character(DOSEDY), ""), @@ -85,6 +233,7 @@ lsting <- adae %>% ASTDYN = ifelse(!is.na(ASTDY), ASTDY, NA), ASTDY = ifelse(!is.na(ASTDY), ASTDY, ""), ASTDTFS = ifelse(!is.na(ASTDTF), "*", ""), + ASTDTFSC = ifelse(!is.na(ASTDTF), paste0(ASTDTF, "*"), ""), AENDT = explicit_na(as.character(AENDT), ""), AENDT = ifelse( nchar(AENDT) == 10, @@ -98,55 +247,116 @@ lsting <- adae %>% ), AENDY = ifelse(!is.na(AENDY), AENDY, ""), AENDTFS = ifelse(!is.na(AENDTF), "*", ""), + AENDTFSC = ifelse(!is.na(AENDTF), paste0(AENDTF, "*"), ""), ADURN = explicit_na(as.character(ADURN), ""), - AEOUTC = explicit_na(AEOUT_DECODE, ""), + AEOUTC = explicit_na(AEOUT, ""), # Optional Variable: COL10/AESEV/AETOXGR # AESEV = explicit_na(AESEV,""), AETOXGR = explicit_na(AETOXGR, ""), - AESER_DECODE = explicit_na(AESER_DECODE, ""), + AESER = explicit_na(AESER, "") + ) + +if (combination_trt) { + lsting <- lsting |> + mutate( + across( + all_of(comb_dosvars), + ~ explicit_na(as.character(.), "") + ), + across( + all_of(comb_dosuvars), + ~ explicit_na(., "") + ), + across( + all_of(comb_dosdyvars), + ~ explicit_na(as.character(.), "") + ) + ) +} + +lsting <- lsting |> + (\(x) { + if (!combination_trt) { + mutate( + x, + COL3 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), + # Optional Column: COL8/AEACN + COL8 = explicit_na(AEACN, ""), + COL9 = explicit_na(AEREL, "") + ) + } else if (combination_trt) { + rowwise(x) |> + mutate( + COL3 = paste( + paste0( + c_across(all_of(comb_trtvars)), + ": ", + c_across(all_of(comb_dosvars)), + " ", + c_across(all_of(comb_dosuvars)), + concat_sep, + c_across(all_of(comb_dosdyvars)) + ), + collapse = "; " + ), + # Optional Column: COL8/AEACNSx + COL8 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_acnvars))), + collapse = "; " + ), + COL9 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_relvars))), + collapse = "; " + ) + ) + } + })() |> + mutate( COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - COL3 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), COL4 = paste(AEDECOD, AETERM, sep = concat_sep), COL5 = case_when( ASTDT == "" ~ "", - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS == "" ~ + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS == "" ~ + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), - ASTDT != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, " (", ASTDY, ")", ASTDTFS), - ASTDT != "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, " (", ASTDY, ")"), + ASTDT != "" & ASTDY != "" ~ paste0(ASTDT, " (", ASTDY, ")"), ), COL6 = case_when( AENDT == "" ~ "", - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS == "" ~ + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS == "" ~ + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), - AENDT != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, " (", AENDY, ")", AENDTFS), - AENDT != "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM != "" & AENDY != "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM == "" & AENDY != "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, " (", AENDY, ")", concat_sep, AENDTFSC), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, " (", AENDY, ")"), + AENDT != "" & AENDY != "" ~ paste0(AENDT, " (", AENDY, ")"), ), COL7 = explicit_na(ADURN, ""), - # Optional Column: COL8/AEACN - COL8 = explicit_na(AEACN_DECODE, ""), - COL9 = explicit_na(AEREL_DECODE, ""), # Optional Variable: COL10/AESEV/AETOXGR - # COL10 = paste(AEOUTC, AESEV, AESER_DECODE, sep = concat_sep) - COL10 = paste(AEOUTC, AETOXGR, AESER_DECODE, sep = concat_sep) - ) %>% + # COL10 = paste(AEOUTC, AESEV, AESER, sep = concat_sep) + COL10 = paste(AEOUTC, AETOXGR, AESER, sep = concat_sep), + # Optional Column: COL11/AESCAT + COL11 = explicit_na(AESCAT, "") + ) |> arrange( COL0, COL1, @@ -185,7 +395,9 @@ lsting <- var_relabel( COL9 = "Relationship to Study Treatment~[super c]", # Optional Variable: COL10/AESEV/AETOXGR # COL10 = paste("Outcome", "Severity", "Serious", sep = concat_sep) - COL10 = paste("Outcome", "Toxicity Grade", "Serious", sep = concat_sep) + COL10 = paste("Outcome", "Toxicity Grade", "Serious", sep = concat_sep), + # Optional Column: COL11/AESCAT + COL11 = "Event Type" ) ############################################################################### @@ -195,7 +407,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -208,6 +422,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 18, 23, 63, 25, 25, 16, 22, 22, 37) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 18, 23, 46, 25, 25, 16, 22, 22, 37, 16) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfae02.R b/tests/testthat/source_code/lsfae02.R index 134cf4f2..926b9b5c 100644 --- a/tests/testthat/source_code/lsfae02.R +++ b/tests/testthat/source_code/lsfae02.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfae02.R -## R version: 4.2.1 -## Short Description: Create LSFAE02: Listing of Treatment-emergent -## Serious Adverse Events -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-22 -## Input: ADAE -## Output: lsfae02.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: JJCS_TLGS_R -## Date: 2024-05-15 -## Description: Added option to display time in start and end dates -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -41,7 +15,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2") -disp_cols <- paste0("COL", 0:10) +sort_cols <- c("COL0", "COL1", "COL2") +disp_cols <- paste0("COL", 0:11) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -50,19 +25,181 @@ tab_titles <- list( ) # Parameter to control whether time should be displayed include_time <- TRUE +# Parameter to control whether imputed date to be displayed +include_imputed_dates <- FALSE + +# Combination treatment parameters + +# Provide whether this is a combination treatments +combination_trt <- FALSE + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc + comb_acnvars <- paste0("AEACNS", seq_len(n_comb_trt)) # This will create a variable list like AEACNS1, AEACNS2 etc + comb_dosvars <- paste0("DOSS", seq_len(n_comb_trt), "ON") # This will create a variable list like DOSS1ON, DOSS2ON etc + comb_dosuvars <- paste0("DOSS", seq_len(n_comb_trt), "U") # This will create a variable list like DOSS1U, DOSS2U etc + comb_dosdyvars <- paste0("DOSS", seq_len(n_comb_trt), "DY") # This will create a variable list like DOSS1DY, DOSS2DY etc +} ############################################################################### # Process data ############################################################################### -adae <- adae_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & TRTEMFL == "Y" & AESER == "Y") +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(!!rlang::sym(popfl) == "Y" & TRTEMFL == "Y" & AESER == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + dplyr::case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male", + SEX == "U" ~ "Unknown", + SEX == "INTERSEX" ~ "Intersex" + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + AEOUT = factor( + case_when( + AEOUT == "FATAL" ~ "Fatal", + AEOUT == "NOT RECOVERED/NOT RESOLVED" ~ "Not Recovered/Not Resolved", + AEOUT == "RECOVERED/RESOLVED" ~ "Recovered/Resolved" + ), + levels = c( + "Fatal", + "Not Recovered/Not Resolved", + "Recovered/Resolved" + ) + ), + AEREL = factor( + case_when( + AEREL == "NOT RELATED" ~ "Not Related", + AEREL == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ), + AEACN = factor( + case_when( + AEACN == "DOSE NOT CHANGED" ~ "Dose Not Changed", + AEACN == "NOT APPLICABLE" ~ "Not Applicable", + AEACN == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + AEACN == "DOSE REDUCED" ~ "Dose Reduced", + AEACN == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + AEACN == "DRUG INTERRUPTED" ~ "Drug Interrupted", + AEACN == "DOSE INCREASED" ~ "Dose Increased", + AEACN == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + +################################### +# Section for combination treatment +################################### + +if (combination_trt) { + adae <- adae |> + mutate( + across( + all_of(comb_relvars), + ~ factor( + case_when( + . == "NOT RELATED" ~ "Not Related", + . == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ) + ), + across( + all_of(comb_acnvars), + ~ factor( + case_when( + . == "DOSE NOT CHANGED" ~ "Dose Not Changed", + . == "NOT APPLICABLE" ~ "Not Applicable", + . == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + . == "DOSE REDUCED" ~ "Dose Reduced", + . == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + . == "DRUG INTERRUPTED" ~ "Drug Interrupted", + . == "DOSE INCREASED" ~ "Dose Increased", + . == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + ) +} -lsting <- adae %>% +################################### + +lsting <- adae |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), DOSEON = explicit_na(as.character(DOSEON), ""), DOSEU = explicit_na(DOSEU, ""), DOSEDY = explicit_na(as.character(DOSEDY), ""), @@ -85,6 +222,7 @@ lsting <- adae %>% ASTDYN = ifelse(!is.na(ASTDY), ASTDY, NA), ASTDY = ifelse(!is.na(ASTDY), ASTDY, ""), ASTDTFS = ifelse(!is.na(ASTDTF), "*", ""), + ASTDTFSC = ifelse(!is.na(ASTDTF), paste0(ASTDTF, "*"), ""), AENDT = explicit_na(as.character(AENDT), ""), AENDT = ifelse( nchar(AENDT) == 10, @@ -98,54 +236,115 @@ lsting <- adae %>% ), AENDY = ifelse(!is.na(AENDY), AENDY, ""), AENDTFS = ifelse(!is.na(AENDTF), "*", ""), + AENDTFSC = ifelse(!is.na(AENDTF), paste0(AENDTF, "*"), ""), ADURN = explicit_na(as.character(ADURN), ""), - AEOUTC = explicit_na(AEOUT_DECODE, ""), + AEOUTC = explicit_na(AEOUT, ""), # Optional Variable: COL10/AESEV/AETOXGR # AESEV = explicit_na(AESEV,""), - AETOXGR = explicit_na(AETOXGR, ""), + AETOXGR = explicit_na(AETOXGR, "") + ) + +if (combination_trt) { + lsting <- lsting |> + mutate( + across( + all_of(comb_dosvars), + ~ explicit_na(as.character(.), "") + ), + across( + all_of(comb_dosuvars), + ~ explicit_na(., "") + ), + across( + all_of(comb_dosdyvars), + ~ explicit_na(as.character(.), "") + ) + ) +} + +lsting <- lsting |> + (\(x) { + if (!combination_trt) { + mutate( + x, + COL3 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), + # Optional Column: COL8/AEACN + COL8 = explicit_na(AEACN, ""), + COL9 = explicit_na(AEREL, "") + ) + } else if (combination_trt) { + rowwise(x) |> + mutate( + COL3 = paste( + paste0( + c_across(all_of(comb_trtvars)), + ": ", + c_across(all_of(comb_dosvars)), + " ", + c_across(all_of(comb_dosuvars)), + concat_sep, + c_across(all_of(comb_dosdyvars)) + ), + collapse = "; " + ), + # Optional Column: COL8/AEACNSx + COL8 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_acnvars))), + collapse = "; " + ), + COL9 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_relvars))), + collapse = "; " + ) + ) + } + })() |> + mutate( COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - COL3 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), COL4 = paste(AEDECOD, AETERM, sep = concat_sep), COL5 = case_when( ASTDT == "" ~ "", - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS == "" ~ + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS == "" ~ + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), - ASTDT != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, " (", ASTDY, ")", ASTDTFS), - ASTDT != "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, " (", ASTDY, ")"), + ASTDT != "" & ASTDY != "" ~ paste0(ASTDT, " (", ASTDY, ")"), ), COL6 = case_when( AENDT == "" ~ "", - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS == "" ~ + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS == "" ~ + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), - AENDT != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, " (", AENDY, ")", AENDTFS), - AENDT != "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM != "" & AENDY != "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM == "" & AENDY != "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, " (", AENDY, ")", concat_sep, AENDTFSC), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, " (", AENDY, ")"), + AENDT != "" & AENDY != "" ~ paste0(AENDT, " (", AENDY, ")"), ), COL7 = explicit_na(ADURN, ""), - # Optional Column: COL8/AEACN - COL8 = explicit_na(AEACN_DECODE, ""), - COL9 = explicit_na(AEREL_DECODE, ""), # Optional Variable: COL10/AESEV/AETOXGR # COL10 = paste(AEOUTC, AESEV, sep = concat_sep) - COL10 = paste(AEOUTC, AETOXGR, sep = concat_sep) - ) %>% + COL10 = paste(AEOUTC, AETOXGR, sep = concat_sep), + # Optional Column: COL11/AESCAT + COL11 = explicit_na(AESCAT, "") + ) |> arrange( COL0, COL1, @@ -184,7 +383,9 @@ lsting <- var_relabel( COL9 = "Relationship to Study Treatment~[super c]", # Optional Variable: COL10/AESEV/AETOXGR # COL10 = paste("Outcome", "Severity", sep = concat_sep) - COL10 = paste("Outcome", "Toxicity Grade", sep = concat_sep) + COL10 = paste("Outcome", "Toxicity Grade", sep = concat_sep), + # Optional Column: COL11/AESCAT + COL11 = "Event Type" ) ############################################################################### @@ -194,7 +395,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -207,6 +410,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 18, 23, 63, 25, 25, 16, 22, 22, 37) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 18, 23, 39, 25, 25, 16, 22, 22, 37, 24) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfae03.R b/tests/testthat/source_code/lsfae03.R index a0ebde10..53dd7487 100644 --- a/tests/testthat/source_code/lsfae03.R +++ b/tests/testthat/source_code/lsfae03.R @@ -1,30 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfae03.R -## R version: 4.2.1 -## Short Description: Create LSFAE03: Listing of Treatment-emergent -## Adverse Events Leading to Permanent -## Discontinuation of Study Treatment -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-22 -## Input: ADAE -## Output: lsfae03.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: JJCS_TLGS_R -## Date: 2024-05-15 -## Description: Added option to display time in start and end dates -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -42,7 +15,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2") -disp_cols <- paste0("COL", 0:9) +sort_cols <- c("COL0", "COL1", "COL2") +disp_cols <- paste0("COL", 0:10) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -51,28 +25,150 @@ tab_titles <- list( ) # Parameter to control whether time should be displayed include_time <- TRUE +# Parameter to control whether imputed date to be displayed +include_imputed_dates <- FALSE + +# Combination treatment parameters + +# Provide whether this is a combination treatments +combination_trt <- FALSE + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc + comb_dosvars <- paste0("DOSS", seq_len(n_comb_trt), "ON") # This will create a variable list like DOSS1ON, DOSS2ON etc + comb_dosuvars <- paste0("DOSS", seq_len(n_comb_trt), "U") # This will create a variable list like DOSS1U, DOSS2U etc + comb_dosdyvars <- paste0("DOSS", seq_len(n_comb_trt), "DY") # This will create a variable list like DOSS1DY, DOSS2DY etc +} ############################################################################### # Process data ############################################################################### -adae <- adae_jnj %>% - filter( - !!rlang::sym(popfl) == "Y" & TRTEMFL == "Y" & AEACN == "DRUG WITHDRAWN" +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(!!rlang::sym(popfl) == "Y" & TRTEMFL == "Y" & TRDISCFL == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + dplyr::case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male", + SEX == "U" ~ "Unknown", + SEX == "INTERSEX" ~ "Intersex" + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + AEOUT = factor( + case_when( + AEOUT == "FATAL" ~ "Fatal", + AEOUT == "NOT RECOVERED/NOT RESOLVED" ~ "Not Recovered/Not Resolved", + AEOUT == "RECOVERED/RESOLVED" ~ "Recovered/Resolved" + ), + levels = c( + "Fatal", + "Not Recovered/Not Resolved", + "Recovered/Resolved" + ) + ), + AESER = factor( + case_when( + AESER == "Y" ~ "Yes", + AESER == "N" ~ "No" + ), + levels = c( + "Yes", + "No" + ) + ), + AEREL = factor( + case_when( + AEREL == "NOT RELATED" ~ "Not Related", + AEREL == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ) ) -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, EOSDY) +################################### +# Section for combination treatment +################################### + +if (combination_trt) { + adae <- adae |> + mutate( + across( + all_of(comb_relvars), + ~ factor( + case_when( + . == "NOT RELATED" ~ "Not Related", + . == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ) + ) + ) +} + +################################### -adae_adsl <- adae %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + select(STUDYID, USUBJID, DCTADY) + +adae_adsl <- adae |> inner_join(adsl, by = c("STUDYID" = "STUDYID", "USUBJID" = "USUBJID")) -lsting <- adae_adsl %>% +lsting <- adae_adsl |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), DOSEON = explicit_na(as.character(DOSEON), ""), DOSEU = explicit_na(DOSEU, ""), DOSEDY = explicit_na(as.character(DOSEDY), ""), @@ -95,6 +191,7 @@ lsting <- adae_adsl %>% ASTDYN = ifelse(!is.na(ASTDY), ASTDY, NA), ASTDY = ifelse(!is.na(ASTDY), ASTDY, ""), ASTDTFS = ifelse(!is.na(ASTDTF), "*", ""), + ASTDTFSC = ifelse(!is.na(ASTDTF), paste0(ASTDTF, "*"), ""), AENDT = explicit_na(as.character(AENDT), ""), AENDT = ifelse( nchar(AENDT) == 10, @@ -108,57 +205,113 @@ lsting <- adae_adsl %>% ), AENDY = ifelse(!is.na(AENDY), AENDY, ""), AENDTFS = ifelse(!is.na(AENDTF), "*", ""), - AEOUTC = explicit_na(AEOUT_DECODE, ""), + AENDTFSC = ifelse(!is.na(AENDTF), paste0(AENDTF, "*"), ""), + AEOUTC = explicit_na(AEOUT, ""), # Optional Variable: COL9/AESEV/AETOXGR # AESEV = explicit_na(AESEV,""), AETOXGR = explicit_na(AETOXGR, ""), - AESER_DECODE = explicit_na(AESER_DECODE, ""), + AESER = explicit_na(AESER, "") + ) + +if (combination_trt) { + lsting <- lsting |> + mutate( + across( + all_of(comb_dosvars), + ~ explicit_na(as.character(.), "") + ), + across( + all_of(comb_dosuvars), + ~ explicit_na(., "") + ), + across( + all_of(comb_dosdyvars), + ~ explicit_na(as.character(.), "") + ) + ) +} + +lsting <- lsting |> + (\(x) { + if (!combination_trt) { + mutate( + x, + COL3 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), + COL8 = explicit_na(AEREL, "") + ) + } else if (combination_trt) { + rowwise(x) |> + mutate( + COL3 = paste( + paste0( + c_across(all_of(comb_trtvars)), + ": ", + c_across(all_of(comb_dosvars)), + " ", + c_across(all_of(comb_dosuvars)), + concat_sep, + c_across(all_of(comb_dosdyvars)) + ), + collapse = "; " + ), + COL8 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_relvars))), + collapse = "; " + ) + ) + } + })() |> + mutate( COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - COL3 = paste0(paste0(DOSEON, " ", DOSEU), concat_sep, DOSEDY), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), COL4 = paste(AEDECOD, AETERM, sep = concat_sep), COL5 = case_when( ASTDT == "" ~ "", - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS == "" ~ + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS == "" ~ + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), - ASTDT != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, " (", ASTDY, ")", ASTDTFS), - ASTDT != "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, " (", ASTDY, ")"), + ASTDT != "" & ASTDY != "" ~ paste0(ASTDT, " (", ASTDY, ")"), ), COL6 = case_when( AENDT == "" ~ "", - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS == "" ~ + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS == "" ~ + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), - AENDT != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, " (", AENDY, ")", AENDTFS), - AENDT != "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM != "" & AENDY != "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM == "" & AENDY != "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, " (", AENDY, ")", concat_sep, AENDTFSC), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, " (", AENDY, ")"), + AENDT != "" & AENDY != "" ~ paste0(AENDT, " (", AENDY, ")"), ), COL7 = case_when( - !is.na(ADURN) & !is.na(EOSDY) ~ paste(ADURN, EOSDY, sep = concat_sep), - !is.na(ADURN) & is.na(EOSDY) ~ paste0(ADURN, concat_sep), - is.na(ADURN) & !is.na(EOSDY) ~ paste0(concat_sep, EOSDY), - is.na(ADURN) & is.na(EOSDY) ~ "" + !is.na(ADURN) & !is.na(DCTADY) ~ paste(ADURN, DCTADY, sep = concat_sep), + !is.na(ADURN) & is.na(DCTADY) ~ paste0(ADURN, concat_sep), + is.na(ADURN) & !is.na(DCTADY) ~ paste0(concat_sep, DCTADY), + is.na(ADURN) & is.na(DCTADY) ~ "" ), - COL8 = explicit_na(AEREL_DECODE, ""), # Optional Variable: COL9/AESEV/AETOXGR - # COL9 = paste(AEOUTC, AESEV, AESER_DECODE, sep = concat_sep) - COL9 = paste(AEOUTC, AETOXGR, AESER_DECODE, sep = concat_sep) - ) %>% + # COL9 = paste(AEOUTC, AESEV, AESER, sep = concat_sep) + COL9 = paste(AEOUTC, AETOXGR, AESER, sep = concat_sep), + # Optional Column: COL10/AESCAT + COL10 = explicit_na(AESCAT, "") + ) |> arrange( COL0, COL1, @@ -193,13 +346,15 @@ lsting <- var_relabel( }, COL7 = paste( "AE Duration (Days)", - "Day of Discontinuation or Completion of Study~[super b]", + "Day of Discontinuation of Study Treatment~[super b]", sep = concat_sep ), COL8 = "Relationship to Study Treatment~[super c]", # Optional Variable: COL9/AESEV/AETOXGR # COL9 = paste("Outcome", "Severity", "Serious", sep = concat_sep) - COL9 = paste("Outcome", "Toxicity Grade", "Serious", sep = concat_sep) + COL9 = paste("Outcome", "Toxicity Grade", "Serious", sep = concat_sep), + # Optional Column: COL10/AESCAT + COL10 = "Event Type" ) ############################################################################### @@ -209,7 +364,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -222,6 +379,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 38, 23, 41, 25, 25, 40, 22, 37) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 35, 23, 30, 25, 25, 38, 22, 37, 16) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfae04.R b/tests/testthat/source_code/lsfae04.R index fe0947b4..e9584afe 100644 --- a/tests/testthat/source_code/lsfae04.R +++ b/tests/testthat/source_code/lsfae04.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfae04.R -## R version: 4.2.1 -## Short Description: Create LSFAE04: Listing of Adverse Events -## Leading to Death -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-22 -## Input: ADAE -## Output: lsfae04.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: JJCS_TLGS_R -## Date: 2024-05-15 -## Description: Added option to display time in start and end dates -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -41,7 +15,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2") -disp_cols <- paste0("COL", 0:10) +sort_cols <- c("COL0", "COL1", "COL2") +disp_cols <- paste0("COL", 0:11) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -50,19 +25,191 @@ tab_titles <- list( ) # Parameter to control whether time should be displayed include_time <- TRUE +# Parameter to control whether imputed date to be displayed +include_imputed_dates <- FALSE + +# Combination treatment parameters + +# Provide whether this is a combination treatments +combination_trt <- FALSE + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc + comb_acnvars <- paste0("AEACNS", seq_len(n_comb_trt)) # This will create a variable list like AEACNS1, AEACNS2 etc + comb_dosvars <- paste0("DOSS", seq_len(n_comb_trt), "ON") # This will create a variable list like DOSS1ON, DOSS2ON etc + comb_dosuvars <- paste0("DOSS", seq_len(n_comb_trt), "U") # This will create a variable list like DOSS1U, DOSS2U etc + comb_dosdyvars <- paste0("DOSS", seq_len(n_comb_trt), "DY") # This will create a variable list like DOSS1DY, DOSS2DY etc +} ############################################################################### # Process data ############################################################################### -adae <- adae_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & AEOUT == "FATAL") +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(!!rlang::sym(popfl) == "Y" & AEOUT == "FATAL") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + dplyr::case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male", + SEX == "U" ~ "Unknown", + SEX == "INTERSEX" ~ "Intersex" + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + AEOUT = factor( + case_when( + AEOUT == "FATAL" ~ "Fatal", + AEOUT == "NOT RECOVERED/NOT RESOLVED" ~ "Not Recovered/Not Resolved", + AEOUT == "RECOVERED/RESOLVED" ~ "Recovered/Resolved" + ), + levels = c( + "Fatal", + "Not Recovered/Not Resolved", + "Recovered/Resolved" + ) + ), + AESER = factor( + case_when( + AESER == "Y" ~ "Yes", + AESER == "N" ~ "No" + ), + levels = c( + "Yes", + "No" + ) + ), + AEREL = factor( + case_when( + AEREL == "NOT RELATED" ~ "Not Related", + AEREL == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ), + AEACN = factor( + case_when( + AEACN == "DOSE NOT CHANGED" ~ "Dose Not Changed", + AEACN == "NOT APPLICABLE" ~ "Not Applicable", + AEACN == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + AEACN == "DOSE REDUCED" ~ "Dose Reduced", + AEACN == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + AEACN == "DRUG INTERRUPTED" ~ "Drug Interrupted", + AEACN == "DOSE INCREASED" ~ "Dose Increased", + AEACN == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + +################################### +# Section for combination treatment +################################### -lsting <- adae %>% +if (combination_trt) { + adae <- adae |> + mutate( + across( + all_of(comb_relvars), + ~ factor( + case_when( + . == "NOT RELATED" ~ "Not Related", + . == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ) + ), + across( + all_of(comb_acnvars), + ~ factor( + case_when( + . == "DOSE NOT CHANGED" ~ "Dose Not Changed", + . == "NOT APPLICABLE" ~ "Not Applicable", + . == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + . == "DOSE REDUCED" ~ "Dose Reduced", + . == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + . == "DRUG INTERRUPTED" ~ "Drug Interrupted", + . == "DOSE INCREASED" ~ "Dose Increased", + . == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + ) +} + +################################### + +lsting <- adae |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), DOSEON = explicit_na(as.character(DOSEON), ""), DOSEU = explicit_na(DOSEU, ""), DOSEDY = explicit_na(as.character(DOSEDY), ""), @@ -85,6 +232,7 @@ lsting <- adae %>% ASTDYN = ifelse(!is.na(ASTDY), ASTDY, NA), ASTDY = ifelse(!is.na(ASTDY), ASTDY, ""), ASTDTFS = ifelse(!is.na(ASTDTF), "*", ""), + ASTDTFSC = ifelse(!is.na(ASTDTF), paste0(ASTDTF, "*"), ""), AENDT = explicit_na(as.character(AENDT), ""), AENDT = ifelse( nchar(AENDT) == 10, @@ -98,54 +246,115 @@ lsting <- adae %>% ), AENDY = ifelse(!is.na(AENDY), AENDY, ""), AENDTFS = ifelse(!is.na(AENDTF), "*", ""), - AEOUTC = explicit_na(AEOUT_DECODE, ""), + AENDTFSC = ifelse(!is.na(AENDTF), paste0(AENDTF, "*"), ""), + AEOUTC = explicit_na(AEOUT, ""), # Optional Variable: COL10/AESEV/AETOXGR # AESEV = explicit_na(AESEV,""), AETOXGR = explicit_na(AETOXGR, ""), - AESER_DECODE = explicit_na(AESER_DECODE, ""), + AESER = explicit_na(AESER, "") + ) + +if (combination_trt) { + lsting <- lsting |> + mutate( + across( + all_of(comb_dosvars), + ~ explicit_na(as.character(.), "") + ), + across( + all_of(comb_dosuvars), + ~ explicit_na(., "") + ), + across( + all_of(comb_dosdyvars), + ~ explicit_na(as.character(.), "") + ) + ) +} + +lsting <- lsting |> + (\(x) { + if (!combination_trt) { + mutate( + x, + COL3 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), + # Optional Column: COL8/AEACN + COL8 = explicit_na(AEACN, ""), + COL9 = explicit_na(AEREL, "") + ) + } else if (combination_trt) { + rowwise(x) |> + mutate( + COL3 = paste( + paste0( + c_across(all_of(comb_trtvars)), + ": ", + c_across(all_of(comb_dosvars)), + " ", + c_across(all_of(comb_dosuvars)), + concat_sep, + c_across(all_of(comb_dosdyvars)) + ), + collapse = "; " + ), + # Optional Column: COL8/AEACNSx + COL8 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_acnvars))), + collapse = "; " + ), + COL9 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_relvars))), + collapse = "; " + ) + ) + } + })() |> + mutate( COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - COL3 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), COL4 = paste(AEDECOD, AETERM, sep = concat_sep), COL5 = ifelse(!is.na(TRTEMFL), "Yes", "No"), COL6 = case_when( ASTDT == "" ~ "", - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS == "" ~ + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS == "" ~ + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), - ASTDT != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, " (", ASTDY, ")", ASTDTFS), - ASTDT != "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, " (", ASTDY, ")"), + ASTDT != "" & ASTDY != "" ~ paste0(ASTDT, " (", ASTDY, ")"), ), COL7 = case_when( AENDT == "" ~ "", - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS == "" ~ + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS == "" ~ + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), - AENDT != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, " (", AENDY, ")", AENDTFS), - AENDT != "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM != "" & AENDY != "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM == "" & AENDY != "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, " (", AENDY, ")", concat_sep, AENDTFSC), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, " (", AENDY, ")"), + AENDT != "" & AENDY != "" ~ paste0(AENDT, " (", AENDY, ")"), ), - # Optional Column: COL8/AEACN - COL8 = explicit_na(AEACN_DECODE, ""), - COL9 = explicit_na(AEREL_DECODE, ""), # Optional Variable: COL10/AESEV/AETOXGR # COL10 = paste(AESEV, AESER, sep = concat_sep) - COL10 = paste(AETOXGR, AESER_DECODE, sep = concat_sep) - ) %>% + COL10 = paste(AETOXGR, AESER, sep = concat_sep), + # Optional Column: COL11/AESCAT + COL11 = explicit_na(AESCAT, "") + ) |> arrange( COL0, COL1, @@ -184,7 +393,9 @@ lsting <- var_relabel( COL9 = "Relationship to Study Treatment~[super c]", # Optional Variable: COL10/AESEV/AETOXGR # COL10 = paste("Severity", "Serious", sep = concat_sep) - COL10 = paste("Toxicity Grade", "Serious", sep = concat_sep) + COL10 = paste("Toxicity Grade", "Serious", sep = concat_sep), + # Optional Column: COL11/AESCAT + COL11 = "Event Type" ) ############################################################################### @@ -194,7 +405,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -207,6 +420,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(18, 25, 24, 23, 78, 8, 24, 24, 22, 22, 15) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(18, 13, 40, 23, 57, 8, 24, 24, 22, 22, 15, 16) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfae05.R b/tests/testthat/source_code/lsfae05.R index da67e0c7..2e4f8a79 100644 --- a/tests/testthat/source_code/lsfae05.R +++ b/tests/testthat/source_code/lsfae05.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfae05.R -## R version: 4.2.1 -## Short Description: Create LSFAE05: Listing of Treatment-emergent -## Adverse Events of Special Interest -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-22 -## Input: ADAE -## Output: lsfae05.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: JJCS_TLGS_R -## Date: 2024-05-15 -## Description: Added option to display time in start and end dates -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -39,9 +13,11 @@ library(stringi) tblid <- "LSFAE05" fileid <- write_path(opath, tblid) popfl <- "SAFFL" +aesivars <- "^CQ[0-9]{2}NAM$" trtvar <- "TRT01A" -key_cols <- c("COL0", "COL1", "COL2") -disp_cols <- paste0("COL", 0:11) +key_cols <- c("COL0", "COL1", "COL2", "COL3") +sort_cols <- c("COL0", "COL1", "COL2", "COL3") +disp_cols <- paste0("COL", 0:12) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -50,20 +26,201 @@ tab_titles <- list( ) # Parameter to control whether time should be displayed include_time <- TRUE +# Parameter to control whether imputed date to be displayed +include_imputed_dates <- FALSE + +# Combination treatment parameters + +# Provide whether this is a combination treatments +combination_trt <- FALSE + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc + comb_acnvars <- paste0("AEACNS", seq_len(n_comb_trt)) # This will create a variable list like AEACNS1, AEACNS2 etc + comb_dosvars <- paste0("DOSS", seq_len(n_comb_trt), "ON") # This will create a variable list like DOSS1ON, DOSS2ON etc + comb_dosuvars <- paste0("DOSS", seq_len(n_comb_trt), "U") # This will create a variable list like DOSS1U, DOSS2U etc + comb_dosdyvars <- paste0("DOSS", seq_len(n_comb_trt), "DY") # This will create a variable list like DOSS1DY, DOSS2DY etc +} ############################################################################### # Process data ############################################################################### -adae <- adae_jnj %>% +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> # Update CQzzNAM variabe based on study requirements - filter(!!rlang::sym(popfl) == "Y" & TRTEMFL == "Y" & CQ01NAM != "") + filter(!!rlang::sym(popfl) == "Y" & TRTEMFL == "Y" & if_any(matches(aesivars), ~ !is.na(.))) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + dplyr::case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male", + SEX == "U" ~ "Unknown", + SEX == "INTERSEX" ~ "Intersex" + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + AEOUT = factor( + case_when( + AEOUT == "FATAL" ~ "Fatal", + AEOUT == "NOT RECOVERED/NOT RESOLVED" ~ "Not Recovered/Not Resolved", + AEOUT == "RECOVERED/RESOLVED" ~ "Recovered/Resolved" + ), + levels = c( + "Fatal", + "Not Recovered/Not Resolved", + "Recovered/Resolved" + ) + ), + AESER = factor( + case_when( + AESER == "Y" ~ "Yes", + AESER == "N" ~ "No" + ), + levels = c( + "Yes", + "No" + ) + ), + AEREL = factor( + case_when( + AEREL == "NOT RELATED" ~ "Not Related", + AEREL == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ), + AEACN = factor( + case_when( + AEACN == "DOSE NOT CHANGED" ~ "Dose Not Changed", + AEACN == "NOT APPLICABLE" ~ "Not Applicable", + AEACN == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + AEACN == "DOSE REDUCED" ~ "Dose Reduced", + AEACN == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + AEACN == "DRUG INTERRUPTED" ~ "Drug Interrupted", + AEACN == "DOSE INCREASED" ~ "Dose Increased", + AEACN == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + +################################### +# Section for combination treatment +################################### + +if (combination_trt) { + adae <- adae |> + mutate( + across( + all_of(comb_relvars), + ~ factor( + case_when( + . == "NOT RELATED" ~ "Not Related", + . == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ) + ), + across( + all_of(comb_acnvars), + ~ factor( + case_when( + . == "DOSE NOT CHANGED" ~ "Dose Not Changed", + . == "NOT APPLICABLE" ~ "Not Applicable", + . == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + . == "DOSE REDUCED" ~ "Dose Reduced", + . == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + . == "DRUG INTERRUPTED" ~ "Drug Interrupted", + . == "DOSE INCREASED" ~ "Dose Increased", + . == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + ) +} + +################################### -lsting <- adae %>% +adae_pvt <- adae |> + tidyr::pivot_longer( + cols = matches(aesivars), + names_to = "CQ", + values_to = "AESIVAR" + ) |> + filter(!is.na(AESIVAR)) + + +lsting <- adae_pvt |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), DOSEON = explicit_na(as.character(DOSEON), ""), DOSEU = explicit_na(DOSEU, ""), DOSEDY = explicit_na(as.character(DOSEDY), ""), @@ -86,6 +243,7 @@ lsting <- adae %>% ASTDYN = ifelse(!is.na(ASTDY), ASTDY, NA), ASTDY = ifelse(!is.na(ASTDY), ASTDY, ""), ASTDTFS = ifelse(!is.na(ASTDTF), "*", ""), + ASTDTFSC = ifelse(!is.na(ASTDTF), paste0(ASTDTF, "*"), ""), AENDT = explicit_na(as.character(AENDT), ""), AENDT = ifelse( nchar(AENDT) == 10, @@ -99,56 +257,124 @@ lsting <- adae %>% ), AENDY = ifelse(!is.na(AENDY), AENDY, ""), AENDTFS = ifelse(!is.na(AENDTF), "*", ""), + AENDTFSC = ifelse(!is.na(AENDTF), paste0(AENDTF, "*"), ""), ADURN = explicit_na(as.character(ADURN), ""), - AEOUTC = explicit_na(AEOUT_DECODE, ""), + AEOUTC = explicit_na(AEOUT, ""), # Optional Variable: COL11/AESEV/AETOXGR # AESEV = explicit_na(AESEV,""), AETOXGR = explicit_na(AETOXGR, ""), - AESER_DECODE = explicit_na(AESER_DECODE, ""), - COL0 = explicit_na(.data[[trtvar]], ""), - COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - COL3 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), - COL4 = explicit_na(CQ01NAM, ""), + AESER = explicit_na(AESER, "") + ) + +if (combination_trt) { + lsting <- lsting |> + mutate( + across( + all_of(comb_dosvars), + ~ explicit_na(as.character(.), "") + ), + across( + all_of(comb_dosuvars), + ~ explicit_na(., "") + ), + across( + all_of(comb_dosdyvars), + ~ explicit_na(as.character(.), "") + ) + ) +} + +lsting <- lsting |> + (\(x) { + if (!combination_trt) { + mutate( + x, + COL4 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), + # To be used if Dose Unit is not used + # COL4 = explicit_na(DOSEDY, ""), + # Optional Column: COL9/AEACN + COL9 = explicit_na(AEACN, ""), + COL10 = explicit_na(AEREL, "") + ) + } else if (combination_trt) { + rowwise(x) |> + mutate( + COL4 = paste( + paste0( + c_across(all_of(comb_trtvars)), + ": ", + c_across(all_of(comb_dosvars)), + " ", + c_across(all_of(comb_dosuvars)), + concat_sep, + c_across(all_of(comb_dosdyvars)) + ), + collapse = "; " + ), + # To be used if Dose Unit is not used + # COL4 = paste( + # paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_dosdyvars))), + # collapse = "; " + # ), + # Optional Column: COL9/AEACNSx + COL9 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_acnvars))), + collapse = "; " + ), + COL10 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_relvars))), + collapse = "; " + ) + ) + } + })() |> + mutate( + COL0 = explicit_na(AESIVAR, ""), + COL1 = explicit_na(.data[[trtvar]], ""), + COL2 = explicit_na(USUBJID, ""), + COL3 = paste(AGE, SEX, RACE, sep = concat_sep), COL5 = paste(AEDECOD, AETERM, sep = concat_sep), COL6 = case_when( ASTDT == "" ~ "", - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS == "" ~ + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS == "" ~ + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), - ASTDT != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, " (", ASTDY, ")", ASTDTFS), - ASTDT != "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, " (", ASTDY, ")"), + ASTDT != "" & ASTDY != "" ~ paste0(ASTDT, " (", ASTDY, ")"), ), COL7 = case_when( AENDT == "" ~ "", - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS == "" ~ + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS == "" ~ + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), - AENDT != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, " (", AENDY, ")", AENDTFS), - AENDT != "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM != "" & AENDY != "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM == "" & AENDY != "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, " (", AENDY, ")", concat_sep, AENDTFSC), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, " (", AENDY, ")"), + AENDT != "" & AENDY != "" ~ paste0(AENDT, " (", AENDY, ")"), ), COL8 = explicit_na(ADURN, ""), - # Optional Column: COL9/AEACN - COL9 = explicit_na(AEACN_DECODE, ""), - COL10 = explicit_na(AEREL_DECODE, ""), # Optional Variable: COL11/AESEV/AETOXGR - # COL11 = paste(AEOUTC, AESEV, AESER_DECODE, sep = concat_sep) - COL11 = paste(AEOUTC, AETOXGR, AESER_DECODE, sep = concat_sep) - ) %>% + # COL11 = paste(AEOUTC, AESEV, AESER, sep = concat_sep) + COL11 = paste(AEOUTC, AETOXGR, AESER, sep = concat_sep), + # Optional Column: COL12/AESCAT + COL12 = explicit_na(AESCAT, "") + ) |> arrange( COL0, COL1, @@ -162,15 +388,15 @@ lsting <- adae %>% lsting <- var_relabel( lsting, - COL0 = "Treatment Group", - COL1 = "Subject ID", - COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), - COL3 = paste( - "Onset Dose (unit)", + COL0 = "AE of Special Interest Category", # "Special" is optional + COL1 = "Treatment Group", + COL2 = "Subject ID", + COL3 = paste("Age (years)", "Sex", "Race", sep = concat_sep), + COL4 = paste( + "Onset Dose (unit)", # "Onset Dose (unit)" is optional "Day of Last Dose~[super a,b]", sep = concat_sep ), - COL4 = "AE of Special Interest Category", COL5 = paste("Preferred Term", "Reported Term", sep = concat_sep), COL6 = if (include_time) { paste("Start Date", "Time (Study Day~[super b])", sep = concat_sep) @@ -188,7 +414,9 @@ lsting <- var_relabel( COL10 = "Relationship to Study Treatment~[super c]", # Optional Variable: COL11/AESEV/AETOXGR # COL11 = paste("Outcome", "Severity", "Serious", sep = concat_sep) - COL11 = paste("Outcome", "Toxicity Grade", "Serious", sep = concat_sep) + COL11 = paste("Outcome", "Toxicity Grade", "Serious", sep = concat_sep), + # Optional Column: COL12/AESCAT + COL12 = "Event Type" ) ############################################################################### @@ -198,7 +426,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -211,6 +441,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 18, 23, 23, 41, 25, 25, 16, 22, 22, 37) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(23, 21, 13, 18, 23, 25, 25, 25, 16, 22, 22, 37, 16) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfae05b.R b/tests/testthat/source_code/lsfae05b.R new file mode 100644 index 00000000..facca605 --- /dev/null +++ b/tests/testthat/source_code/lsfae05b.R @@ -0,0 +1,446 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) +library(stringi) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LSFAE05b" +fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +aeivars <- "^SMQ[0-9]{2}NAM$" +trtvar <- "TRT01A" +key_cols <- c("COL0", "COL1", "COL2", "COL3") +sort_cols <- c("COL0", "COL1", "COL2", "COL3") +disp_cols <- paste0("COL", 0:12) +concat_sep <- " / " +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +# Parameter to control whether time should be displayed +include_time <- TRUE +# Parameter to control whether imputed date to be displayed +include_imputed_dates <- FALSE + +# Combination treatment parameters + +# Provide whether this is a combination treatments +combination_trt <- FALSE + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc + comb_acnvars <- paste0("AEACNS", seq_len(n_comb_trt)) # This will create a variable list like AEACNS1, AEACNS2 etc + comb_dosvars <- paste0("DOSS", seq_len(n_comb_trt), "ON") # This will create a variable list like DOSS1ON, DOSS2ON etc + comb_dosuvars <- paste0("DOSS", seq_len(n_comb_trt), "U") # This will create a variable list like DOSS1U, DOSS2U etc + comb_dosdyvars <- paste0("DOSS", seq_len(n_comb_trt), "DY") # This will create a variable list like DOSS1DY, DOSS2DY etc +} + +############################################################################### +# Process data +############################################################################### + +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + # Update CQzzNAM variabe based on study requirements + filter(!!rlang::sym(popfl) == "Y" & TRTEMFL == "Y" & if_any(matches(aeivars), ~ !is.na(.))) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + dplyr::case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male", + SEX == "U" ~ "Unknown", + SEX == "INTERSEX" ~ "Intersex" + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + AEOUT = factor( + case_when( + AEOUT == "FATAL" ~ "Fatal", + AEOUT == "NOT RECOVERED/NOT RESOLVED" ~ "Not Recovered/Not Resolved", + AEOUT == "RECOVERED/RESOLVED" ~ "Recovered/Resolved" + ), + levels = c( + "Fatal", + "Not Recovered/Not Resolved", + "Recovered/Resolved" + ) + ), + AESER = factor( + case_when( + AESER == "Y" ~ "Yes", + AESER == "N" ~ "No" + ), + levels = c( + "Yes", + "No" + ) + ), + AEREL = factor( + case_when( + AEREL == "NOT RELATED" ~ "Not Related", + AEREL == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ), + AEACN = factor( + case_when( + AEACN == "DOSE NOT CHANGED" ~ "Dose Not Changed", + AEACN == "NOT APPLICABLE" ~ "Not Applicable", + AEACN == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + AEACN == "DOSE REDUCED" ~ "Dose Reduced", + AEACN == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + AEACN == "DRUG INTERRUPTED" ~ "Drug Interrupted", + AEACN == "DOSE INCREASED" ~ "Dose Increased", + AEACN == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + +################################### +# Section for combination treatment +################################### + +if (combination_trt) { + adae <- adae |> + mutate( + across( + all_of(comb_relvars), + ~ factor( + case_when( + . == "NOT RELATED" ~ "Not Related", + . == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ) + ), + across( + all_of(comb_acnvars), + ~ factor( + case_when( + . == "DOSE NOT CHANGED" ~ "Dose Not Changed", + . == "NOT APPLICABLE" ~ "Not Applicable", + . == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + . == "DOSE REDUCED" ~ "Dose Reduced", + . == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + . == "DRUG INTERRUPTED" ~ "Drug Interrupted", + . == "DOSE INCREASED" ~ "Dose Increased", + . == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + ) +} + +################################### + +adae_pvt <- adae |> + tidyr::pivot_longer( + cols = matches(aeivars), + names_to = "SMQ", + values_to = "AEIVAR" + ) |> + filter(!is.na(AEIVAR)) + +lsting <- adae_pvt |> + mutate( + AGE = explicit_na(as.character(AGE), ""), + SEX = explicit_na(SEX, ""), + RACE = explicit_na(RACE, ""), + DOSEON = explicit_na(as.character(DOSEON), ""), + DOSEU = explicit_na(DOSEU, ""), + DOSEDY = explicit_na(as.character(DOSEDY), ""), + AEDECOD = explicit_na(AEDECOD, ""), + AETERM = ifelse( + is.na(AETERM), + "", + stringi::stri_trans_totitle(gsub("\\$", "", AETERM)) + ), + ASTDT = ifelse( + nchar(as.character(ASTDT)) == 10, + toupper(format(ASTDT, "%d%b%Y")), + "" + ), + ASTTM = ifelse( + include_time & !is.na(ASTDTM), + substr(as.character(ASTDTM), 12, 16), + "" + ), + ASTDYN = ifelse(!is.na(ASTDY), ASTDY, NA), + ASTDY = ifelse(!is.na(ASTDY), ASTDY, ""), + ASTDTFS = ifelse(!is.na(ASTDTF), "*", ""), + ASTDTFSC = ifelse(!is.na(ASTDTF), paste0(ASTDTF, "*"), ""), + AENDT = explicit_na(as.character(AENDT), ""), + AENDT = ifelse( + nchar(AENDT) == 10, + toupper(format(as.Date(AENDT), "%d%b%Y")), + "" + ), + AENTM = ifelse( + include_time & !is.na(AENDTM), + substr(as.character(AENDTM), 12, 16), + "" + ), + AENDY = ifelse(!is.na(AENDY), AENDY, ""), + AENDTFS = ifelse(!is.na(AENDTF), "*", ""), + AENDTFSC = ifelse(!is.na(AENDTF), paste0(AENDTF, "*"), ""), + ADURN = explicit_na(as.character(ADURN), ""), + AEOUTC = explicit_na(AEOUT, ""), + # Optional Variable: COL11/AESEV/AETOXGR + # AESEV = explicit_na(AESEV,""), + AETOXGR = explicit_na(AETOXGR, ""), + AESER = explicit_na(AESER, "") + ) + +if (combination_trt) { + lsting <- lsting |> + mutate( + across( + all_of(comb_dosvars), + ~ explicit_na(as.character(.), "") + ), + across( + all_of(comb_dosuvars), + ~ explicit_na(., "") + ), + across( + all_of(comb_dosdyvars), + ~ explicit_na(as.character(.), "") + ) + ) +} + +lsting <- lsting |> + (\(x) { + if (!combination_trt) { + mutate( + x, + COL4 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), + # To be used if Dose Unit is not used + # COL4 = explicit_na(DOSEDY, ""), + # Optional Column: COL9/AEACN + COL9 = explicit_na(AEACN, ""), + COL10 = explicit_na(AEREL, "") + ) + } else if (combination_trt) { + rowwise(x) |> + mutate( + COL4 = paste( + paste0( + c_across(all_of(comb_trtvars)), + ": ", + c_across(all_of(comb_dosvars)), + " ", + c_across(all_of(comb_dosuvars)), + concat_sep, + c_across(all_of(comb_dosdyvars)) + ), + collapse = "; " + ), + # To be used if Dose Unit is not used + # COL4 = paste( + # paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_dosdyvars))), + # collapse = "; " + # ), + # Optional Column: COL9/AEACNSx + COL9 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_acnvars))), + collapse = "; " + ), + COL10 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_relvars))), + collapse = "; " + ) + ) + } + })() |> + mutate( + COL0 = explicit_na(AEIVAR, ""), + COL1 = explicit_na(.data[[trtvar]], ""), + COL2 = explicit_na(USUBJID, ""), + COL3 = paste(AGE, SEX, RACE, sep = concat_sep), + COL5 = paste(AEDECOD, AETERM, sep = concat_sep), + COL6 = case_when( + ASTDT == "" ~ "", + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC == "" ~ + paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC == "" ~ + paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, " (", ASTDY, ")"), + ASTDT != "" & ASTDY != "" ~ paste0(ASTDT, " (", ASTDY, ")"), + ), + COL7 = case_when( + AENDT == "" ~ "", + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC == "" ~ + paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC == "" ~ + paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), + include_time & AENDT != "" & AENTM != "" & AENDY != "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM == "" & AENDY != "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, " (", AENDY, ")", concat_sep, AENDTFSC), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, " (", AENDY, ")"), + AENDT != "" & AENDY != "" ~ paste0(AENDT, " (", AENDY, ")"), + ), + COL8 = explicit_na(ADURN, ""), + # Optional Variable: COL11/AESEV/AETOXGR + # COL11 = paste(AEOUTC, AESEV, AESER, sep = concat_sep) + COL11 = paste(AEOUTC, AETOXGR, AESER, sep = concat_sep), + # Optional Column: COL12/AESCAT + COL12 = explicit_na(AESCAT, "") + ) |> + arrange( + COL0, + COL1, + COL2, + !is.na(ASTDYN), + ASTDYN, + if (include_time) ASTDTM else ASTDT, + AEDECOD, + AETERM + ) + +lsting <- var_relabel( + lsting, + COL0 = "AE of Interest Category", # "Special" is optional + COL1 = "Treatment Group", + COL2 = "Subject ID", + COL3 = paste("Age (years)", "Sex", "Race", sep = concat_sep), + COL4 = paste( + "Onset Dose (unit)", # "Onset Dose (unit)" is optional + "Day of Last Dose~[super a,b]", + sep = concat_sep + ), + COL5 = paste("Preferred Term", "Reported Term", sep = concat_sep), + COL6 = if (include_time) { + paste("Start Date", "Time (Study Day~[super b])", sep = concat_sep) + } else { + "Start Date (Study Day~[super b])" + }, + COL7 = if (include_time) { + paste("End Date", "Time (Study Day~[super b])", sep = concat_sep) + } else { + "End Date (Study Day~[super b])" + }, + COL8 = "AE Duration (Days)", + # Optional Column: COL9/AEACN + COL9 = "Action Taken With Study Treatment", + COL10 = "Relationship to Study Treatment~[super c]", + # Optional Variable: COL11/AESEV/AETOXGR + # COL11 = paste("Outcome", "Severity", "Serious", sep = concat_sep) + COL11 = paste("Outcome", "Toxicity Grade", "Serious", sep = concat_sep), + # Optional Column: COL12/AESCAT + COL12 = "Event Type" +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(28, 21, 13, 18, 23, 25, 25, 25, 16, 22, 22, 37, 16) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfae06.R b/tests/testthat/source_code/lsfae06.R new file mode 100644 index 00000000..172ec971 --- /dev/null +++ b/tests/testthat/source_code/lsfae06.R @@ -0,0 +1,434 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) +library(stringi) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LSFAE06" +fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +trtvar <- "TRT01A" +key_cols <- c("COL0", "COL1", "COL2") +sort_cols <- c("COL0", "COL1", "COL2") +disp_cols <- paste0("COL", 0:11) +concat_sep <- " / " +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +# Parameter to control whether time should be displayed # from ASTDTM +include_time <- TRUE +# Parameter to control whether imputed date to be displayed +include_imputed_dates <- FALSE + +# Combination treatment parameters + +# Provide whether this is a combination treatments +combination_trt <- FALSE + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc + comb_acnvars <- paste0("AEACNS", seq_len(n_comb_trt)) # This will create a variable list like AEACNS1, AEACNS2 etc + comb_dosvars <- paste0("DOSS", seq_len(n_comb_trt), "ON") # This will create a variable list like DOSS1ON, DOSS2ON etc + comb_dosuvars <- paste0("DOSS", seq_len(n_comb_trt), "U") # This will create a variable list like DOSS1U, DOSS2U etc + comb_dosdyvars <- paste0("DOSS", seq_len(n_comb_trt), "DY") # This will create a variable list like DOSS1DY, DOSS2DY etc +} + +############################################################################### +# Process data +############################################################################### + +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(!!rlang::sym(popfl) == "Y" & TRTEMFL == "Y" & AEACN == "DOSE REDUCED") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + dplyr::case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male", + SEX == "U" ~ "Unknown", + SEX == "INTERSEX" ~ "Intersex" + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + AEOUT = factor( + case_when( + AEOUT == "FATAL" ~ "Fatal", + AEOUT == "NOT RECOVERED/NOT RESOLVED" ~ "Not Recovered/Not Resolved", + AEOUT == "RECOVERED/RESOLVED" ~ "Recovered/Resolved" + ), + levels = c( + "Fatal", + "Not Recovered/Not Resolved", + "Recovered/Resolved" + ) + ), + AESER = factor( + case_when( + AESER == "Y" ~ "Yes", + AESER == "N" ~ "No" + ), + levels = c( + "Yes", + "No" + ) + ), + AEREL = factor( + case_when( + AEREL == "NOT RELATED" ~ "Not Related", + AEREL == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ), + AEACN = factor( + case_when( + AEACN == "DOSE NOT CHANGED" ~ "Dose Not Changed", + AEACN == "NOT APPLICABLE" ~ "Not Applicable", + AEACN == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + AEACN == "DOSE REDUCED" ~ "Dose Reduced", + AEACN == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + AEACN == "DRUG INTERRUPTED" ~ "Drug Interrupted", + AEACN == "DOSE INCREASED" ~ "Dose Increased", + AEACN == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + +################################### +# Section for combination treatment +################################### + +if (combination_trt) { + adae <- adae |> + mutate( + across( + all_of(comb_relvars), + ~ factor( + case_when( + . == "NOT RELATED" ~ "Not Related", + . == "RELATED" ~ "Related" + ), + levels = c( + "Not Related", + "Related" + ) + ) + ), + across( + all_of(comb_acnvars), + ~ factor( + case_when( + . == "DOSE NOT CHANGED" ~ "Dose Not Changed", + . == "NOT APPLICABLE" ~ "Not Applicable", + . == "DRUG WITHDRAWN" ~ "Drug Withdrawn", + . == "DOSE REDUCED" ~ "Dose Reduced", + . == "DOSE RATE REDUCED" ~ "Dose Rate Reduced", + . == "DRUG INTERRUPTED" ~ "Drug Interrupted", + . == "DOSE INCREASED" ~ "Dose Increased", + . == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Dose Not Changed", + "Not Applicable", + "Drug Withdrawn", + "Dose Reduced", + "Dose Rate Reduced", + "Drug Interrupted", + "Dose Increased", + "Unknown" + ) + ) + ) + ) +} + +################################### + +lsting <- adae |> + mutate( + AGE = explicit_na(as.character(AGE), ""), + SEX = explicit_na(SEX, ""), + RACE = explicit_na(RACE, ""), + DOSEON = explicit_na(as.character(DOSEON), ""), + DOSEU = explicit_na(DOSEU, ""), + DOSEDY = explicit_na(as.character(DOSEDY), ""), + AEDECOD = explicit_na(AEDECOD, ""), + AETERM = ifelse( + is.na(AETERM), + "", + stringi::stri_trans_totitle(gsub("\\$", "", AETERM)) + ), + ASTDT = ifelse( + nchar(as.character(ASTDT)) == 10, + toupper(format(ASTDT, "%d%b%Y")), + "" + ), + ASTTM = ifelse( + include_time & !is.na(ASTDTM), + substr(as.character(ASTDTM), 12, 16), + "" + ), + ASTDYN = ifelse(!is.na(ASTDY), ASTDY, NA), + ASTDY = ifelse(!is.na(ASTDY), ASTDY, ""), + ASTDTFS = ifelse(!is.na(ASTDTF), "*", ""), + ASTDTFSC = ifelse(!is.na(ASTDTF), paste0(ASTDTF, "*"), ""), + AENDT = explicit_na(as.character(AENDT), ""), + AENDT = ifelse( + nchar(AENDT) == 10, + toupper(format(as.Date(AENDT), "%d%b%Y")), + "" + ), + AENTM = ifelse( + include_time & !is.na(AENDTM), + substr(as.character(AENDTM), 12, 16), + "" + ), + AENDY = ifelse(!is.na(AENDY), AENDY, ""), + AENDTFS = ifelse(!is.na(AENDTF), "*", ""), + AENDTFSC = ifelse(!is.na(AENDTF), paste0(AENDTF, "*"), ""), + ADURN = explicit_na(as.character(ADURN), ""), + AEOUTC = explicit_na(AEOUT, ""), + # Optional Variable: COL10/AESEV/AETOXGR + # AESEV = explicit_na(AESEV,""), + AETOXGR = explicit_na(AETOXGR, ""), + AESER = explicit_na(AESER, "") + ) + +if (combination_trt) { + lsting <- lsting |> + mutate( + across( + all_of(comb_dosvars), + ~ explicit_na(as.character(.), "") + ), + across( + all_of(comb_dosuvars), + ~ explicit_na(., "") + ), + across( + all_of(comb_dosdyvars), + ~ explicit_na(as.character(.), "") + ) + ) +} + +lsting <- lsting |> + (\(x) { + if (!combination_trt) { + mutate( + x, + COL3 = paste(paste0(DOSEON, " ", DOSEU), DOSEDY, sep = concat_sep), + # To be used if Dose Unit is not used + # COL3 = explicit_na(DOSEDY, ""), + # Optional Column: COL8/AEACN + COL8 = explicit_na(AEACN, ""), + COL9 = explicit_na(AEREL, "") + ) + } else if (combination_trt) { + rowwise(x) |> + mutate( + COL3 = paste( + paste0( + c_across(all_of(comb_trtvars)), + ": ", + c_across(all_of(comb_dosvars)), + " ", + c_across(all_of(comb_dosuvars)), + concat_sep, + c_across(all_of(comb_dosdyvars)) + ), + collapse = "; " + ), + # To be used if Dose Unit is not used + # COL3 = paste( + # paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_dosdyvars))), + # collapse = "; " + # ), + # Optional Column: COL8/AEACNSx + COL8 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_acnvars))), + collapse = "; " + ), + COL9 = paste( + paste0(c_across(all_of(comb_trtvars)), ": ", c_across(all_of(comb_relvars))), + collapse = "; " + ) + ) + } + })() |> + mutate( + COL0 = explicit_na(.data[[trtvar]], ""), + COL1 = explicit_na(USUBJID, ""), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), + COL4 = paste(AEDECOD, AETERM, sep = concat_sep), + COL5 = case_when( + ASTDT == "" ~ "", + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFSC == "" ~ + paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_time & include_imputed_dates & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFSC == "" ~ + paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC != "" ~ + paste0(ASTDT, " (", ASTDY, ")", concat_sep, ASTDTFSC), + include_imputed_dates & ASTDT != "" & ASTDY != "" & ASTDTFSC == "" ~ paste0(ASTDT, " (", ASTDY, ")"), + ASTDT != "" & ASTDY != "" ~ paste0(ASTDT, " (", ASTDY, ")"), + ), + COL6 = case_when( + AENDT == "" ~ "", + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFSC == "" ~ + paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", concat_sep, AENDTFSC), + include_time & include_imputed_dates & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFSC == "" ~ + paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), + include_time & AENDT != "" & AENTM != "" & AENDY != "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), + include_time & AENDT != "" & AENTM == "" & AENDY != "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC != "" ~ + paste0(AENDT, " (", AENDY, ")", concat_sep, AENDTFSC), + include_imputed_dates & AENDT != "" & AENDY != "" & AENDTFSC == "" ~ paste0(AENDT, " (", AENDY, ")"), + AENDT != "" & AENDY != "" ~ paste0(AENDT, " (", AENDY, ")"), + ), + COL7 = explicit_na(ADURN, ""), + # Optional Variable: COL10/AESEV/AETOXGR + # COL10 = paste(AEOUTC, AESEV, AESER, sep = concat_sep) + COL10 = paste(AEOUTC, AETOXGR, AESER, sep = concat_sep), + # Optional Column: COL11/AESCAT + COL11 = explicit_na(AESCAT, "") + ) |> + arrange( + COL0, + COL1, + COL2, + !is.na(ASTDYN), + ASTDYN, + if (include_time) ASTDTM else ASTDT, + AEDECOD, + AETERM + ) + +lsting <- var_relabel( + lsting, + COL0 = "Treatment Group", + COL1 = "Subject ID", + COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), + COL3 = paste( + "Onset Dose (unit)", # "Onset Dose (unit)" is optional + "Day of Last Dose~[super a,b]", + sep = concat_sep + ), + COL4 = paste("Preferred Term", "Reported Term", sep = concat_sep), + COL5 = if (include_time) { + paste("Start Date", "Time (Study Day~[super b])", sep = concat_sep) + } else { + "Start Date (Study Day~[super b])" + }, + COL6 = if (include_time) { + paste("End Date", "Time (Study Day~[super b])", sep = concat_sep) + } else { + "End Date (Study Day~[super b])" + }, + COL7 = "AE Duration (Days)", + # Optional Column: COL8/AEACN + COL8 = "Action Taken With Study Treatment", + COL9 = "Relationship to Study Treatment~[super c]", + # Optional Variable: COL10/AESEV/AETOXGR + # COL10 = paste("Outcome", "Severity", "Serious", sep = concat_sep) + COL10 = paste("Outcome", "Toxicity Grade", "Serious", sep = concat_sep), + # Optional Column: COL11/AESCAT + COL11 = "Event Type" +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" +) + +############################################################################### +# Add titles and footnotes: +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(21, 13, 35, 23, 30, 25, 25, 16, 22, 22, 37, 16) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfae06a.R b/tests/testthat/source_code/lsfae06a.R deleted file mode 100644 index 297ae73c..00000000 --- a/tests/testthat/source_code/lsfae06a.R +++ /dev/null @@ -1,203 +0,0 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfae06a.R -## R version: 4.2.1 -## Short Description: Create LSFAE06a: Selected [Narrow / Broad] OCMQs -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-07-21 -## Input: ADAEOCMQ -## Output: lsfae06a.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Removed source(read_path(cl, ...)) lines and added appropriate library imports -## Rev #: 2 -## Modified By: -## Reporting Effort: JJCS_TLGS_R -## Date: 2024-05-15 -## Description: Added option to display time in start and end dates -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(rlistings) -library(junco) -library(rlistings) - -############################################################################### -# Define script level parameters -############################################################################### - -tblid <- "LSFAE06a" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) -popfl <- "SAFFL" -trtvar <- "TRT01A" -ocmqclass <- "Narrow" -key_cols <- c("COL0", "COL1", "COL2", "COL3") -disp_cols <- paste0("COL", 0:8) -concat_sep <- " / " -# Parameter to control whether time should be displayed -include_time <- TRUE - -############################################################################### -# Process data -############################################################################### - -adaeocmq <- adaeocmq_jnj |> - filter( - !!sym(popfl) == "Y" & - !is.na(OCMQNAM) & - OCMQCLSS == ocmqclass & - TRTEMFL == "Y" - ) - -lsting <- adaeocmq |> - mutate( - AGE = explicit_na(as.character(AGE), ""), - SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), - AEDECOD = explicit_na(AEDECOD, ""), - AETERM = ifelse( - is.na(AETERM), - "", - string_to_title(gsub("\\$", "", AETERM)) - ), - ASTDT = ifelse( - nchar(as.character(ASTDT)) == 10, - toupper(format(ASTDT, "%d%b%Y")), - "" - ), - ASTTM = ifelse( - include_time & !is.na(ASTDTM), - substr(as.character(ASTDTM), 12, 16), - "" - ), - ASTDYN = ifelse(!is.na(ASTDY), ASTDY, NA), - ASTDY = ifelse(!is.na(ASTDY), ASTDY, ""), - ASTDTFS = ifelse(!is.na(ASTDTF), "*", ""), - AENDT = explicit_na(as.character(AENDT), ""), - AENDT = ifelse( - nchar(AENDT) == 10, - toupper(format(as.Date(AENDT), "%d%b%Y")), - "" - ), - AENTM = ifelse( - include_time & !is.na(AENDTM), - substr(as.character(AENDTM), 12, 16), - "" - ), - AENDY = ifelse(!is.na(AENDY), AENDY, ""), - AENDTFS = ifelse(!is.na(AENDTF), "*", ""), - AEOUTC = explicit_na(AEOUT_DECODE, ""), - AESEV = explicit_na(AESEV, ""), - AESER_DECODE = explicit_na(AESER_DECODE, ""), - COL0 = OCMQNAM, - COL1 = explicit_na(.data[[trtvar]], ""), - COL2 = explicit_na(USUBJID, ""), - COL3 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - COL4 = paste(AEDECOD, AETERM, sep = concat_sep), - COL5 = case_when( - ASTDT == "" ~ "", - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), - ASTDT != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, " (", ASTDY, ")", ASTDTFS), - ASTDT != "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, " (", ASTDY, ")"), - ), - COL6 = case_when( - AENDT == "" ~ "", - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), - AENDT != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, " (", AENDY, ")", AENDTFS), - AENDT != "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, " (", AENDY, ")"), - ), - COL7 = explicit_na(AEACN_DECODE, ""), - COL8 = paste(AEOUTC, AESEV, AESER_DECODE, sep = concat_sep) - ) |> - arrange( - COL0, - COL1, - COL2, - !is.na(ASTDYN), - ASTDYN, - if (include_time) ASTDTM else ASTDT, - AEDECOD, - AETERM - ) - -lsting <- var_relabel( - lsting, - COL0 = "OCMQ", - COL1 = "Treatment Group", - COL2 = "Subject ID", - COL3 = paste("Age (years)", "Sex", "Race", sep = concat_sep), - COL4 = paste("Preferred Term", "Reported Term", sep = concat_sep), - COL5 = if (include_time) { - paste("Start Date", "Time (Study Day~[super a])", sep = concat_sep) - } else { - "Start Date (Study Day~[super a])" - }, - COL6 = if (include_time) { - paste("End Date", "Time (Study Day~[super a])", sep = concat_sep) - } else { - "End Date (Study Day~[super a])" - }, - COL7 = "Action Taken With Study Treatment", - COL8 = paste("Outcome", "Severity", "Serious", sep = concat_sep) -) - -############################################################################### -# Build listing -############################################################################### - -result <- rlistings::as_listing( - df = lsting, - key_cols = key_cols, - disp_cols = disp_cols -) - -############################################################################### -# Add titles and footnotes: -############################################################################### - -result <- set_titles(result, tab_titles) - -############################################################################### -# Output listing -############################################################################### - -colwidth <- c(22, 21, 13, 28, 92, 25, 25, 22, 37) - -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfae06b.R b/tests/testthat/source_code/lsfae06b.R deleted file mode 100644 index 825af7d4..00000000 --- a/tests/testthat/source_code/lsfae06b.R +++ /dev/null @@ -1,203 +0,0 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfae06b.R -## R version: 4.2.1 -## Short Description: Create LSFAE06b: Selected [Narrow / Broad] OCMQs -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-07-21 -## Input: ADAEOCMQ -## Output: lsfae06b.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Removed source(read_path(cl, ...)) lines and added appropriate library imports -## Rev #: 2 -## Modified By: -## Reporting Effort: JJCS_TLGS_R -## Date: 2024-05-15 -## Description: Added option to display time in start and end dates -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(rlistings) -library(junco) -library(rlistings) - -############################################################################### -# Define script level parameters -############################################################################### - -tblid <- "LSFAE06b" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) -popfl <- "SAFFL" -trtvar <- "TRT01A" -ocmqclass <- "Narrow" -key_cols <- c("COL0", "COL1", "COL2", "COL3") -disp_cols <- paste0("COL", 0:8) -concat_sep <- " / " -# Parameter to control whether time should be displayed -include_time <- TRUE - -############################################################################### -# Process data -############################################################################### - -adaeocmq <- adaeocmq_jnj |> - filter( - !!sym(popfl) == "Y" & - !is.na(OCMQNAM) & - OCMQCLSS == ocmqclass & - TRTEMFL == "Y" - ) - -lsting <- adaeocmq |> - mutate( - AGE = explicit_na(as.character(AGE), ""), - SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), - AEDECOD = explicit_na(AEDECOD, ""), - AETERM = ifelse( - is.na(AETERM), - "", - string_to_title(gsub("\\$", "", AETERM)) - ), - ASTDT = ifelse( - nchar(as.character(ASTDT)) == 10, - toupper(format(ASTDT, "%d%b%Y")), - "" - ), - ASTTM = ifelse( - include_time & !is.na(ASTDTM), - substr(as.character(ASTDTM), 12, 16), - "" - ), - ASTDYN = ifelse(!is.na(ASTDY), ASTDY, NA), - ASTDY = ifelse(!is.na(ASTDY), ASTDY, ""), - ASTDTFS = ifelse(!is.na(ASTDTF), "*", ""), - AENDT = explicit_na(as.character(AENDT), ""), - AENDT = ifelse( - nchar(AENDT) == 10, - toupper(format(as.Date(AENDT), "%d%b%Y")), - "" - ), - AENTM = ifelse( - include_time & !is.na(AENDTM), - substr(as.character(AENDTM), 12, 16), - "" - ), - AENDY = ifelse(!is.na(AENDY), AENDY, ""), - AENDTFS = ifelse(!is.na(AENDTF), "*", ""), - AEOUTC = explicit_na(AEOUT_DECODE, ""), - AETOXGR = explicit_na(AETOXGR, ""), - AESER_DECODE = explicit_na(AESER_DECODE, ""), - COL0 = OCMQNAM, - COL1 = explicit_na(.data[[trtvar]], ""), - COL2 = explicit_na(USUBJID, ""), - COL3 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - COL4 = paste(AEDECOD, AETERM, sep = concat_sep), - COL5 = case_when( - ASTDT == "" ~ "", - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM != "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")", ASTDTFS), - include_time & ASTDT != "" & ASTTM == "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), - ASTDT != "" & ASTDY != "" & ASTDTFS != "" ~ - paste0(ASTDT, " (", ASTDY, ")", ASTDTFS), - ASTDT != "" & ASTDY != "" & ASTDTFS == "" ~ - paste0(ASTDT, " (", ASTDY, ")"), - ), - COL6 = case_when( - AENDT == "" ~ "", - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM != "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")", AENDTFS), - include_time & AENDT != "" & AENTM == "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), - AENDT != "" & AENDY != "" & AENDTFS != "" ~ - paste0(AENDT, " (", AENDY, ")", AENDTFS), - AENDT != "" & AENDY != "" & AENDTFS == "" ~ - paste0(AENDT, " (", AENDY, ")"), - ), - COL7 = explicit_na(AEACN_DECODE, ""), - COL8 = paste(AEOUTC, AETOXGR, AESER_DECODE, sep = concat_sep) - ) |> - arrange( - COL0, - COL1, - COL2, - !is.na(ASTDYN), - ASTDYN, - if (include_time) ASTDTM else ASTDT, - AEDECOD, - AETERM - ) - -lsting <- var_relabel( - lsting, - COL0 = "OCMQ", - COL1 = "Treatment Group", - COL2 = "Subject ID", - COL3 = paste("Age (years)", "Sex", "Race", sep = concat_sep), - COL4 = paste("Preferred Term", "Reported Term", sep = concat_sep), - COL5 = if (include_time) { - paste("Start Date", "Time (Study Day~[super a])", sep = concat_sep) - } else { - "Start Date (Study Day~[super a])" - }, - COL6 = if (include_time) { - paste("End Date", "Time (Study Day~[super a])", sep = concat_sep) - } else { - "End Date (Study Day~[super a])" - }, - COL7 = "Action Taken With Study Treatment", - COL8 = paste("Outcome", "Toxicity Grade", "Serious", sep = concat_sep) -) - -############################################################################### -# Build listing -############################################################################### - -result <- rlistings::as_listing( - df = lsting, - key_cols = key_cols, - disp_cols = disp_cols -) - -############################################################################### -# Add titles and footnotes: -############################################################################### - -result <- set_titles(result, tab_titles) - -############################################################################### -# Output listing -############################################################################### - -colwidth <- c(22, 21, 13, 28, 92, 25, 25, 22, 37) - -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfdth01.R b/tests/testthat/source_code/lsfdth01.R index 8f5d57a7..6d988e40 100644 --- a/tests/testthat/source_code/lsfdth01.R +++ b/tests/testthat/source_code/lsfdth01.R @@ -1,28 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfdth01.R -## R version: 4.2.1 -## Short Description: Create LSFDTH01: Listing of Deaths -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-12 -## Input: ADSL, ADEXSUM -## Output: lsfdth01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -38,7 +13,9 @@ tblid <- "LSFDTH01" fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" -key_cols <- c("COL0", "COL1") +paramcd_dur <- "TRTDURM" +key_cols <- c("COL0", "COL1", "COL2") +sort_cols <- c("COL0", "COL1", "COL2") disp_cols <- paste0("COL", 0:8) concat_sep <- " / " tab_titles <- list( @@ -47,48 +24,88 @@ tab_titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) + ############################################################################### # Process data ############################################################################### -adsl <- adsl_jnj %>% +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male" + ), + levels = c("Male", "Female") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) |> filter(!!rlang::sym(popfl) == "Y" & DTHFL == "Y") -adexsum <- adexsum_jnj %>% - filter(PARAMCD == "TRTDURM") %>% - select(STUDYID, USUBJID, AVAL) +adexsum <- adexsum_jnj |> + filter(PARAMCD == paramcd_dur) |> + select(STUDYID, USUBJID, AVAL, PARAM) adexsum_dig <- tidytlg:::make_precision_data( df = adexsum, decimal = 4, precisionby = "STUDYID", precisionon = "AVAL" -) %>% +) |> rename(c(VALDIGMAX = "decimal")) -adsl_adexsum <- adsl %>% - inner_join(adexsum, by = c("STUDYID", "USUBJID")) %>% +adsl_adexsum <- adsl |> + inner_join(adexsum, by = c("STUDYID", "USUBJID")) |> left_join(adexsum_dig, by = c("STUDYID" = "STUDYID")) -lsting <- adsl_adexsum %>% +lsting <- adsl_adexsum |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), LDOSE = explicit_na(as.character(LDOSE), ""), LDOSU = explicit_na(LDOSU, ""), DTHCAUS = explicit_na(stringr::str_to_sentence(DTHCAUS), ""), DTHTERM = explicit_na(stringr::str_to_sentence(DTHTERM), ""), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - COL3 = paste(LDOSE, LDOSU), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), + COL3 = paste0(LDOSE, " (", LDOSU, ")"), COL4 = case_when( is.na(AVAL) ~ "", - VALDIGMAX == 0 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 1 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL) + VALDIGMAX == 0 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 1 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL) ), # Optional Column: COL5/TRTEDT/TRTEDY COL5 = ifelse( @@ -114,7 +131,7 @@ lsting <- adsl_adexsum %>% ) ), COL8 = paste(DTHCAUS, DTHTERM, sep = concat_sep) - ) %>% + ) |> arrange(COL0, COL1) lsting <- var_relabel( @@ -122,8 +139,18 @@ lsting <- var_relabel( COL0 = "Treatment Group", COL1 = "Subject ID", COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), - COL3 = "Last Dose of Study Treatment", - COL4 = "Duration of Treatment Months~[super a]", + # Optional Column: COL3/LDOSE/LDOSU + COL3 = "Dose (Unit) of Last Dose of Study Treatment", + COL4 = paste0( + "Duration of Treatment ", + tolower(trimws(gsub( + "[()]", + "", + sub("(?i)^duration of treatment[, ]*", "", adsl_adexsum[["PARAM"]][1], perl = TRUE) + ))), + "~[super a]" + ), + # Optional Column: COL5/TRTEDT/TRTEDY COL5 = "Date of Last Dose of Study Treatment (Study Day~[super b])", # Optional Column: COL6/LDSTODTH @@ -131,7 +158,7 @@ lsting <- var_relabel( COL7 = "Date of Death (Study Day~[super d])", COL8 = paste( "Primary Cause of Death (Preferred Term", - "Verbatim", + "Verbatim)", sep = concat_sep ) ) @@ -143,7 +170,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -156,6 +185,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 63, 24, 18, 19, 31, 41, 22, 46) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 63, 33, 27, 19, 31, 41, 22, 28) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfecg01.R b/tests/testthat/source_code/lsfecg01.R index cd385891..c121009c 100644 --- a/tests/testthat/source_code/lsfecg01.R +++ b/tests/testthat/source_code/lsfecg01.R @@ -1,32 +1,7 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfecg01.R -## R version: 4.2.1 -## Short Description: Create LSFECG01: Listing of Subjects With -## [Criteria] ECG Values -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-24 -## Input: ADEG -## Output: lsfecg01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) +library(tidyr) library(rtables) library(rlistings) library(junco) @@ -41,7 +16,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2", "COL3") -disp_cols <- paste0("COL", 0:9) +sort_cols <- c("COL0", "COL1", "COL2", "COL3") +disp_cols <- paste0("COL", 0:10) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -49,19 +25,59 @@ tab_titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) - ############################################################################### # Process data ############################################################################### -adeg <- adeg_jnj %>% - filter(!!rlang::sym(popfl) == "Y") +adeg <- adeg_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + PARAM = factor( + .data$PARAM, + levels = unique(.data[["PARAM"]])[order(unique(.data[["PARAMN"]]))] + ), + AVISIT = factor( + .data[["AVISIT"]], + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) -adeg_crit <- adeg %>% +adeg_crit <- adeg |> # Update CRITyFL variabes based on study requirements - # filter(CRIT1FL == "Y" | CRIT2FL == "Y") %>% - filter(CRIT2FL == "Y") %>% - select(STUDYID, USUBJID, PARAMCD) %>% + filter(CRIT1FL == "Y" | CRIT2FL == "Y") |> + select(STUDYID, USUBJID, PARAMCD) |> distinct() adeg_dig <- tidytlg:::make_precision_data( @@ -69,10 +85,10 @@ adeg_dig <- tidytlg:::make_precision_data( decimal = 4, precisionby = "PARAMCD", precisionon = "AVAL" -) %>% +) |> rename(c(VALDIGMAX = "decimal")) -adeg_list <- adeg_crit %>% +adeg_list <- adeg_crit |> inner_join( adeg, by = c( @@ -80,14 +96,14 @@ adeg_list <- adeg_crit %>% "USUBJID" = "USUBJID", "PARAMCD" = "PARAMCD" ) - ) %>% + ) |> inner_join(adeg_dig, by = c("PARAMCD" = "PARAMCD")) -lsting <- adeg_list %>% +lsting <- adeg_list |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), ADT = ifelse( nchar(as.character(ADT)) == 10, toupper(format(ADT, "%d%b%Y")), @@ -97,90 +113,56 @@ lsting <- adeg_list %>% ADYN = ifelse(!is.na(ADY), ADY, NA), ADY = ifelse(!is.na(ADY), ADY, "--"), VAL_RES = case_when( - is.na(VALDIGMAX) & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 0 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 1 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL), - VALDIGMAX == 2 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 2, as_char = TRUE, na_char = NULL), - VALDIGMAX == 3 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 3, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 4 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 4, as_char = TRUE, na_char = NULL), + is.na(VALDIGMAX) & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 0 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 1 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL), + VALDIGMAX == 2 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 2, as_char = TRUE, na_char = NULL), + VALDIGMAX == 3 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 3, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 4 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 4, as_char = TRUE, na_char = NULL), !is.na(AVALC) ~ AVALC ), - VAL_HL = case_when( - !is.na(ANRIND) ~ substr(ANRIND, 1, 1), + # Optional Column: CRITyFL + CRIT1L = ifelse(CRIT1FL == "Y", as.character(CRIT1), NA_character_), + CRIT2L = ifelse(CRIT2FL == "Y", as.character(CRIT2), NA_character_), + TREM_FL = case_when( + TRTEMFL == "Y" ~ "Yes", .default = NA - ), - # !!!! remove EGCLSIG creation !!!! - EGCLSIG = "Y", - VAL_CS = case_when( - EGCLSIG == "Y" ~ "CS", - EGCLSIG == "N" ~ "NCS", - .default = NA - ), - VAL = case_when( - !is.na(VAL_RES) & !is.na(VAL_HL) & !is.na(VAL_CS) ~ paste( - VAL_RES, - VAL_HL, - VAL_CS, - sep = " " - ), - !is.na(VAL_RES) & !is.na(VAL_HL) & is.na(VAL_CS) ~ paste( - VAL_RES, - VAL_HL, - sep = " " - ), - !is.na(VAL_RES) & is.na(VAL_HL) & !is.na(VAL_CS) ~ paste( - VAL_RES, - VAL_CS, - sep = " " - ), - !is.na(VAL_RES) & is.na(VAL_HL) & is.na(VAL_CS) ~ VAL_RES, - .default = NA - ), - # CRIT = case_when( - # (is.na(CRIT1) | CRIT1FL == "N") & (is.na(CRIT2) | CRIT2FL == "N") - # ~ "", - # !is.na(CRIT1) & CRIT1FL == "Y" ~ CRIT1, - # !is.na(CRIT2) & CRIT2FL == "Y" ~ CRIT2, - # ), - CRIT = case_when( - is.na(CRIT2) | CRIT2FL == "N" ~ "", - !is.na(CRIT2) & CRIT2FL == "Y" ~ CRIT2, - ), + ) + ) |> + unite( + "CRITL", + CRIT1L, + CRIT2L, + sep = ", ", + na.rm = TRUE, + remove = FALSE + ) |> + mutate( COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), COL3 = explicit_na(PARAM, ""), # Optional Variable: ATM COL4 = paste(ADT, concat_sep, ATM, " (", ADY, ")", sep = ""), COL5 = explicit_na(AVISIT, ""), # Optional Column: COL6/ATPT COL6 = explicit_na(ATPT, ""), - COL7 = explicit_na(VAL, ""), + COL7 = explicit_na(VAL_RES, ""), # Optional Column: COL8/CHG COL8 = case_when( is.na(CHG) ~ "", is.na(VALDIGMAX) & !is.na(AVAL) & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 0 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 1 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 1, as_char = TRUE, na_char = NULL), - VALDIGMAX == 2 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 2, as_char = TRUE, na_char = NULL), - VALDIGMAX == 3 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 3, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 4 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 4, as_char = TRUE, na_char = NULL) + VALDIGMAX == 0 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 1 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 1, as_char = TRUE, na_char = NULL), + VALDIGMAX == 2 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 2, as_char = TRUE, na_char = NULL), + VALDIGMAX == 3 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 3, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 4 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 4, as_char = TRUE, na_char = NULL) ), # Optional Column: COL9/CRITy - COL9 = explicit_na(CRIT, "") - ) %>% + COL9 = explicit_na(CRITL, ""), + COL10 = explicit_na(TREM_FL, "") + ) |> arrange(COL0, COL1, COL2, COL3, !is.na(ADYN), ADYN, ADTM) lsting <- var_relabel( @@ -200,9 +182,10 @@ lsting <- var_relabel( COL6 = "Time Point", COL7 = "Result", # Optional Column: COL8/CHG - COL8 = "Change from Baseline", + COL8 = "Change From Baseline", # Optional Column: COL9/CRITy - COL9 = "Criteria" + COL9 = "Criteria", + COL10 = "Treatment-emergent?" ) ############################################################################### @@ -212,7 +195,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + sort_cols = sort_cols, + disp_cols = disp_cols, + round_type = "sas" ) ############################################################################### @@ -225,6 +210,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 18, 20, 75, 16, 75, 18, 15, 14) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 18, 32, 75, 16, 50, 12, 15, 14, 18) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfecg02.R b/tests/testthat/source_code/lsfecg02.R index db046334..a1a111e4 100644 --- a/tests/testthat/source_code/lsfecg02.R +++ b/tests/testthat/source_code/lsfecg02.R @@ -1,28 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfecg02.R -## R version: 4.2.1 -## Short Description: Create LSFECG02: Listing of ECG Values -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-09-12 -## Input: ADEG -## Output: lsfecg02.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -40,7 +15,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2", "COL3") -disp_cols <- paste0("COL", 0:9) +sort_cols <- c("COL0", "COL1", "COL2", "COL3") +disp_cols <- paste0("COL", 0:10) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -53,25 +29,67 @@ tab_titles <- list( # Process data ############################################################################### -adeg <- adeg_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & PARAMCD != "EGALL") +adeg <- adeg_jnj |> + filter(!!rlang::sym(popfl) == "Y" & PARAMCD != "EGALL") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + PARAM = factor( + .data$PARAM, + levels = unique(.data[["PARAM"]])[order(unique(.data[["PARAMN"]]))] + ), + AVISIT = factor( + .data[["AVISIT"]], + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) adeg_dig <- tidytlg:::make_precision_data( df = adeg, decimal = 4, precisionby = "PARAMCD", precisionon = "AVAL" -) %>% +) |> rename(c(VALDIGMAX = "decimal")) -adeg_list <- adeg %>% +adeg_list <- adeg |> inner_join(adeg_dig, by = c("PARAMCD" = "PARAMCD")) -lsting <- adeg_list %>% +lsting <- adeg_list |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), ADT = ifelse( nchar(as.character(ADT)) == 10, toupper(format(ADT, "%d%b%Y")), @@ -81,47 +99,27 @@ lsting <- adeg_list %>% ADYN = ifelse(!is.na(ADY), ADY, NA), ADY = ifelse(!is.na(ADY), ADY, "--"), VAL_RES = case_when( - is.na(VALDIGMAX) & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 0 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 1 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL), - VALDIGMAX == 2 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 2, as_char = TRUE, na_char = NULL), - VALDIGMAX == 3 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 3, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 4 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 4, as_char = TRUE, na_char = NULL), + is.na(VALDIGMAX) & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 0 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 1 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL), + VALDIGMAX == 2 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 2, as_char = TRUE, na_char = NULL), + VALDIGMAX == 3 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 3, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 4 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 4, as_char = TRUE, na_char = NULL), !is.na(AVALC) ~ AVALC ), - VAL_HL = case_when( - !is.na(ANRIND) ~ substr(ANRIND, 1, 1), - .default = NA - ), VAL_CS = case_when( - EGCLSIG == "Y" ~ "CS", - EGCLSIG == "N" ~ "NCS", + EGCLSIG == "Y" & PARAMCD == "INTP" ~ "CS", + EGCLSIG == "N" & PARAMCD == "INTP" ~ "NCS", .default = NA ), VAL = case_when( - !is.na(VAL_RES) & !is.na(VAL_HL) & !is.na(VAL_CS) ~ paste( - VAL_RES, - VAL_HL, - VAL_CS, - sep = " " - ), - !is.na(VAL_RES) & !is.na(VAL_HL) & is.na(VAL_CS) ~ paste( - VAL_RES, - VAL_HL, - sep = " " - ), - !is.na(VAL_RES) & is.na(VAL_HL) & !is.na(VAL_CS) ~ paste( - VAL_RES, - VAL_CS, - sep = " " - ), - !is.na(VAL_RES) & is.na(VAL_HL) & is.na(VAL_CS) ~ VAL_RES, + !is.na(VAL_RES) & !is.na(VAL_CS) ~ + paste( + VAL_RES, + VAL_CS, + sep = " " + ), + !is.na(VAL_RES) & is.na(VAL_CS) ~ VAL_RES, .default = NA ), CRIT = case_when( @@ -129,9 +127,13 @@ lsting <- adeg_list %>% !is.na(CRIT1) & CRIT1FL == "Y" ~ CRIT1, !is.na(CRIT2) & CRIT2FL == "Y" ~ CRIT2, ), + TREM_FL = case_when( + TRTEMFL == "Y" ~ "Yes", + .default = NA + ), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), COL3 = explicit_na(PARAM, ""), # Optional Variable: ATM COL4 = paste(ADT, concat_sep, ATM, " (", ADY, ")", sep = ""), @@ -144,20 +146,16 @@ lsting <- adeg_list %>% is.na(CHG) ~ "", is.na(VALDIGMAX) & !is.na(AVAL) & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 0 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 1 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 1, as_char = TRUE, na_char = NULL), - VALDIGMAX == 2 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 2, as_char = TRUE, na_char = NULL), - VALDIGMAX == 3 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 3, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 4 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 4, as_char = TRUE, na_char = NULL) + VALDIGMAX == 0 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 1 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 1, as_char = TRUE, na_char = NULL), + VALDIGMAX == 2 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 2, as_char = TRUE, na_char = NULL), + VALDIGMAX == 3 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 3, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 4 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 4, as_char = TRUE, na_char = NULL) ), # Optional Column: COL9/CRITy - COL9 = explicit_na(CRIT, "") - ) %>% + COL9 = explicit_na(CRIT, ""), + COL10 = explicit_na(TREM_FL, "") + ) |> arrange(COL0, COL1, COL2, COL3, !is.na(ADYN), ADYN, ADTM) lsting <- var_relabel( @@ -177,9 +175,10 @@ lsting <- var_relabel( COL6 = "Time Point", COL7 = "Result", # Optional Column: COL8/CHG - COL8 = "Change from Baseline", + COL8 = "Change From Baseline", # Optional Column: COL9/CRITy - COL9 = "Criteria" + COL9 = "Criteria", + COL10 = "Treatment-emergent?" ) ############################################################################### @@ -189,7 +188,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + sort_cols = sort_cols, + disp_cols = disp_cols, + round_type = "sas" ) ############################################################################### @@ -205,38 +206,14 @@ result <- set_titles(result, tab_titles) # should be split into multiple parts # The split below is based on the treatment groups # Update as-needed for your study -result1 <- result %>% +result1 <- result |> filter(toupper(.data[[trtvar]]) == "XANOMELINE LOW DOSE") -colwidth <- c(21, 13, 18, 38, 75, 15, 50, 24, 15, 14) - -tt_to_tlgrtf( - colwidths = colwidth, - head(result1, 100), - file = paste0(fileid, "PART1OF3"), - orientation = "landscape" -) - -result2 <- result %>% - filter(toupper(.data[[trtvar]]) == "XANOMELINE HIGH DOSE") - -colwidth <- c(21, 13, 18, 29, 74, 27, 50, 24, 15, 14) - -tt_to_tlgrtf( - colwidths = colwidth, - head(result2, 100), - file = paste0(fileid, "PART2OF3"), - orientation = "landscape" -) - -result3 <- result %>% - filter(toupper(.data[[trtvar]]) == "PLACEBO") -colwidth <- c(18, 13, 18, 41, 75, 16, 50, 24, 15, 14) +colwidth <- c(21, 13, 18, 28, 75, 15, 43, 25, 15, 14, 18) tt_to_tlgrtf( - colwidths = colwidth, - head(result3, 100), - file = paste0(fileid, "PART3OF3"), + head(result, 100), + file = paste0(fileid), orientation = "landscape" ) diff --git a/tests/testthat/source_code/lsflab01.R b/tests/testthat/source_code/lsflab01.R index 43a1cbaf..17322b04 100644 --- a/tests/testthat/source_code/lsflab01.R +++ b/tests/testthat/source_code/lsflab01.R @@ -1,35 +1,10 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsflab01.R -## R version: 4.2.1 -## Short Description: Create LSFLAB01: Listing of Subjects With -## [Criteria] Laboratory Values -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-24 -## Input: ADLB, ADSL -## Output: lsflab01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) library(rtables) library(rlistings) library(junco) + ############################################################################### # Define script level parameters ############################################################################### @@ -39,7 +14,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2", "COL3") -disp_cols <- paste0("COL", 0:10) +sort_cols <- c("COL0", "COL1", "COL2", "COL3") +disp_cols <- paste0("COL", 0:11) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -47,26 +23,68 @@ tab_titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) +# Parameter to control Criteria Flag column: "CRIT" (default MCRIT1FL & MCRIT2FL), +# -- "ATOXGR" if user needs ATOXGR to be displayed +crit_var <- "CRIT" ############################################################################### # Process data ############################################################################### -adlb <- adlb_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & is.na(DTYPE)) - - -adlb <- adlb[1:1000, ] # make it manageable +adlb <- adlb_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + PARAM := ordered(PARAM, levels = { + # Sort by PARCAT1, PARCAT3N then PARAM and PARCAT3 not displayed used only for sorting + unique(PARAM[order(PARCAT1, PARCAT3N, PARAM)]) + }), + AVISIT = factor( + .data[["AVISIT"]], + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) -adlb_crit <- adlb %>% +adlb_crit <- adlb |> # Update filter criteria as needed for your study - # MCRIT1ML/MCRI2ML or ATOXGRN will be used + # MCRIT1ML/MCRII2ML or ATOXGRN will be used filter( ((!is.na(MCRIT1ML) & as.numeric(substr(MCRIT1ML, 7, 8)) >= 2) | (!is.na(MCRIT2ML) & as.numeric(substr(MCRIT2ML, 7, 8)) >= 2)) - ) %>% - # filter(ATOXGRN >= 3) %>% - select(STUDYID, USUBJID, PARAMCD) %>% + ) |> + # filter(ATOXGRN >= 3) |> + select(STUDYID, USUBJID, PARAMCD) |> distinct() adlb_dig <- tidytlg:::make_precision_data( @@ -74,10 +92,10 @@ adlb_dig <- tidytlg:::make_precision_data( decimal = 4, precisionby = "PARAMCD", precisionon = "AVAL" -) %>% +) |> rename(c(VALDIGMAX = "decimal")) -adlb_list <- adlb_crit %>% +adlb_list <- adlb_crit |> inner_join( adlb, by = c( @@ -85,35 +103,30 @@ adlb_list <- adlb_crit %>% "USUBJID" = "USUBJID", "PARAMCD" = "PARAMCD" ) - ) %>% + ) |> inner_join(adlb_dig, by = c("PARAMCD" = "PARAMCD")) -lsting <- adlb_list %>% +lsting <- adlb_list |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), + ADTS = ADT, ADT = ifelse( nchar(as.character(ADT)) == 10, toupper(format(ADT, "%d%b%Y")), - "---------" + "" ), - ATM = ifelse(!is.na(ADTM), substr(as.character(ADTM), 12, 16), "--:--"), + ATM = ifelse(!is.na(ADTM), substr(as.character(ADTM), 12, 16), ""), ADYN = ifelse(!is.na(ADY), ADY, NA), ADY = ifelse(!is.na(ADY), ADY, "--"), VAL_RES = case_when( - is.na(VALDIGMAX) & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 0 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 1 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL), - VALDIGMAX == 2 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 2, as_char = TRUE, na_char = NULL), - VALDIGMAX == 3 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 3, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 4 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 4, as_char = TRUE, na_char = NULL), + is.na(VALDIGMAX) & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 0 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 1 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL), + VALDIGMAX == 2 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 2, as_char = TRUE, na_char = NULL), + VALDIGMAX == 3 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 3, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 4 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 4, as_char = TRUE, na_char = NULL), !is.na(AVALC) ~ AVALC ), VAL_HL = case_when( @@ -126,22 +139,25 @@ lsting <- adlb_list %>% .default = NA ), VAL = case_when( - !is.na(VAL_RES) & !is.na(VAL_HL) & !is.na(VAL_CS) ~ paste( - VAL_RES, - VAL_HL, - VAL_CS, - sep = " " - ), - !is.na(VAL_RES) & !is.na(VAL_HL) & is.na(VAL_CS) ~ paste( - VAL_RES, - VAL_HL, - sep = " " - ), - !is.na(VAL_RES) & is.na(VAL_HL) & !is.na(VAL_CS) ~ paste( - VAL_RES, - VAL_CS, - sep = " " - ), + !is.na(VAL_RES) & !is.na(VAL_HL) & !is.na(VAL_CS) ~ + paste( + VAL_RES, + VAL_HL, + VAL_CS, + sep = " " + ), + !is.na(VAL_RES) & !is.na(VAL_HL) & is.na(VAL_CS) ~ + paste( + VAL_RES, + VAL_HL, + sep = " " + ), + !is.na(VAL_RES) & is.na(VAL_HL) & !is.na(VAL_CS) ~ + paste( + VAL_RES, + VAL_CS, + sep = " " + ), !is.na(VAL_RES) & is.na(VAL_HL) & is.na(VAL_CS) ~ VAL_RES, .default = NA ), @@ -177,22 +193,26 @@ lsting <- adlb_list %>% !is.na(MCRIT1ML) ~ MCRIT1ML, !is.na(MCRIT2ML) ~ MCRIT2ML, ), + # Optional column based on title + ATOXGR = explicit_na(ATOXGR, ""), # CRIT = ifelse(!is.na(ATOXGR), as.character(ATOXGR), ""), REFRL = case_when( is.na(LBSTNRLO) ~ as.character(ANRLO), - !is.na(LBSTNRLQ) & !is.na(LBSTNRLO) ~ paste0( - LBSTNRLQ, - as.character(LBSTNRLO) - ), + !is.na(LBSTNRLQ) & !is.na(LBSTNRLO) ~ + paste0( + LBSTNRLQ, + as.character(LBSTNRLO) + ), is.na(LBSTNRLQ) & !is.na(LBSTNRLO) ~ as.character(LBSTNRLO), .default = "NA" ), REFRH = case_when( is.na(LBSTNRHI) ~ as.character(ANRHI), - !is.na(LBSTNRHQ) & !is.na(LBSTNRHI) ~ paste0( - LBSTNRHQ, - as.character(LBSTNRHI) - ), + !is.na(LBSTNRHQ) & !is.na(LBSTNRHI) ~ + paste0( + LBSTNRHQ, + as.character(LBSTNRHI) + ), is.na(LBSTNRHQ) & !is.na(LBSTNRHI) ~ as.character(LBSTNRHI), .default = "NA" ), @@ -201,37 +221,45 @@ lsting <- adlb_list %>% !is.na(REFRL) & is.na(REFRH) ~ paste(REFRL, " ", sep = "- "), is.na(REFRL) & !is.na(REFRH) ~ paste(" ", REFRH, sep = "- ") ), + TRTEM_FL = case_when( + TRTEMFL == "Y" ~ "Yes", + TRTEMFL == "N" ~ "No", + .default = NA + ), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), COL3 = explicit_na(PARAM, ""), # Optional Variable: ATM - COL4 = paste0(ADT, concat_sep, ATM, " (", ADY, ")", sep = ""), + COL4 = case_when( + ADT == "" ~ "", + ADT != "" & ATM != "" & ADY != "" ~ paste0(ADT, concat_sep, ATM, " (", ADY, ")"), + ADT != "" & ATM == "" & ADY != "" ~ paste0(ADT, concat_sep, "--:--", " (", ADY, ")"), + ADT != "" & ATM != "" & ADY == "" ~ paste0(ADT, concat_sep, ATM, " (-)"), + ADT != "" & ATM == "" & ADY == "" ~ paste0(ADT, concat_sep, "--:--", " (-)"), + ), COL5 = explicit_na(AVISIT, ""), # Optional Column: COL6/ATPT COL6 = explicit_na(ATPT, ""), COL7 = explicit_na(VAL, ""), - # Optional Variable: COL8/MCRIT1ML/MCRIT2ML/ATOXGR - COL8 = explicit_na(CRIT, ""), + # Optional Variable: COL8/(MCRIT1ML/MCRIT2ML)/ATOXGR + COL8 = explicit_na(.data[[crit_var]], ""), COL9 = case_when( is.na(CHG) ~ "", is.na(VALDIGMAX) & !is.na(AVAL) & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 0 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 1 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 1, as_char = TRUE, na_char = NULL), - VALDIGMAX == 2 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 2, as_char = TRUE, na_char = NULL), - VALDIGMAX == 3 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 3, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 4 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 4, as_char = TRUE, na_char = NULL) + VALDIGMAX == 0 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 1 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 1, as_char = TRUE, na_char = NULL), + VALDIGMAX == 2 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 2, as_char = TRUE, na_char = NULL), + VALDIGMAX == 3 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 3, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 4 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 4, as_char = TRUE, na_char = NULL) ), - # Optional Column: COL10/ANRLO/ANRHI + # Optional Column: COL10/LBSTNRLO/LBSTNRHI/LBSTNRLQ/LBSTNRHQ/ANRLO/ANRHI COL10 = explicit_na(REFR, ""), - ) %>% - arrange(COL0, COL1, COL2, COL3, COL4, !is.na(ADYN), ADYN, ADTM) + # Optional Column: COL11/TRTEMFL + COL11 = explicit_na(TRTEM_FL, "") + ) |> + arrange(COL0, COL1, COL2, COL3, ADTS, !is.na(ADYN), ADYN, ADTM) lsting <- var_relabel( lsting, @@ -249,12 +277,13 @@ lsting <- var_relabel( # Optional Column: COL6/ATPT COL6 = "Time Point", COL7 = "Result", - # Optional Variable: COL8/MCRIT1ML/MCRIT2ML/ATOXGR - COL8 = "FDA Threshold Level", - # COL9 = "Toxicity Grade", + # Optional Variable: COL8/(MCRIT1ML/MCRIT2ML)/ATOXGR + COL8 = "Criteria Flag", COL9 = "Change From Baseline", - # Optional Column: COL10/ANRLO/ANRHI - COL10 = "Reference Range" + # Optional Column: COL10/LBSTNRLO/LBSTNRHI/LBSTNRLQ/LBSTNRHQ/ANRLO/ANRHI + COL10 = "Reference Range", + # Optional Column: COL11/TRTEMFL + COL11 = "Treatment-emergent?" ) ############################################################################### @@ -264,7 +293,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + sort_cols = sort_cols, + disp_cols = disp_cols, + round_type = "sas" ) ############################################################################### @@ -277,6 +308,10 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 18, 37, 40, 18, 25, 12, 68, 15, 18) +colwidth <- c(21, 13, 18, 30, 75, 15, 25, 15, 22, 15, 18, 18) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +tt_to_tlgrtf( + head(result, 100), + file = fileid, + orientation = "landscape" +) diff --git a/tests/testthat/source_code/lsflab02.R b/tests/testthat/source_code/lsflab02.R new file mode 100644 index 00000000..e4dbf741 --- /dev/null +++ b/tests/testthat/source_code/lsflab02.R @@ -0,0 +1,202 @@ +library(envsetup) +library(tern) +library(dplyr) +library(tidyr) +library(rlistings) +library(junco) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LSFLAB02" +fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +trtvar <- "TRT01A" +key_cols <- c("COL0", "COL1", "COL2") +sort_cols <- c("COL0", "COL1", "COL2", "ADT", "ADY") +disp_cols <- paste0("COL", 0:8) +concat_sep <- " / " +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +central_lab <- c("CENTRAL") +############################################################################### +# Process data +############################################################################### + +addili_raw <- addili_jnj + +addili <- addili_raw |> + filter( + !!rlang::sym(popfl) == "Y", + PARAMCD %in% c("ALT", "AST", "ALP", "BILI"), + !is.na(.data[[trtvar]]), + is.na(DTYPE) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + AVISIT = factor( + .data[["AVISIT"]], + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) + +addili_crit <- addili |> + filter(ONTRTFL == "Y" & CRIT1FL == "Y") |> + select(STUDYID, USUBJID) |> + distinct() + +addili_joined <- addili_crit |> + inner_join( + addili, + by = c( + "STUDYID" = "STUDYID", + "USUBJID" = "USUBJID" + ) + ) + +addili_list <- addili_joined |> + mutate( + R2ANRHI_CHAR = sprintf("%.2f", R2ANRHI), + # For BILI records of Hy's Law subjects where the visit-level flag is set, + # concatenate R2ANRHI value with the flag "^" + # Non-central lab values are additionally suffixed with "*" + VAL = paste0( + R2ANRHI_CHAR, + if_else(!is.na(LBNAM) & toupper(LBNAM) != toupper(central_lab), "*", ""), + if_else( + PARAMCD == "BILI" & !is.na(ANL05FL) & ANL05FL == "Y" & !is.na(CRIT1FL) & CRIT1FL == "Y", + "^", + "" + ), + if_else( + PARAMCD == "BILI" & !is.na(ANL07FL) & ANL07FL == "Y" & !is.na(CRIT1FL) & CRIT1FL == "Y", + "#", + "" + ) + ) + ) |> + group_by( + STUDYID, + USUBJID, + TRT01A, + AGE, + SEX, + RACE, + AVISIT, + ADT, + ADY, + PARAMCD + ) |> + summarise( + VAL = paste(unique(na.omit(VAL)), collapse = ", "), + .groups = "drop" + ) |> + pivot_wider( + names_from = PARAMCD, + values_from = VAL + ) + +lsting <- addili_list |> + mutate( + AGE = as.character(AGE), + SEX = as.character(SEX), + RACE = as.character(RACE), + ADT_CHAR = ifelse(!is.na(ADT), toupper(format(ADT, "%d%b%Y")), ""), + ADY_CHAR = ifelse(!is.na(ADY), as.character(ADY), "--"), + COL0 = .data[[trtvar]], + COL1 = explicit_na(USUBJID, ""), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), + COL3 = case_when( + ADT_CHAR == "" ~ "", + ADT_CHAR != "" & ADY_CHAR != "" ~ paste0(ADT_CHAR, " (", ADY_CHAR, ")"), + ADT_CHAR != "" & ADY_CHAR == "" ~ paste0(ADT_CHAR, " (-)") + ), + COL4 = AVISIT, + COL5 = if ("ALT" %in% names(addili_list)) ALT else "", + COL6 = if ("AST" %in% names(addili_list)) AST else "", + COL7 = if ("ALP" %in% names(addili_list)) ALP else "", + COL8 = if ("BILI" %in% names(addili_list)) BILI else "" + ) |> + mutate(across(c(COL5, COL6, COL7, COL8), ~ ifelse(is.na(.), "", as.character(.)))) |> + arrange(COL0, COL1, ADT, ADY) + +lsting <- var_relabel( + lsting, + COL0 = "Treatment Group", + COL1 = "Subject ID", + COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), + COL3 = "Assessment Date (Study Day~[super a])", + COL4 = "Visit", + COL5 = "ALT\\line(x ULN)", + COL6 = "AST\\line(x ULN)", + COL7 = "ALP\\line(x ULN)", + COL8 = "TBILI\\line(x ULN)" +) + + +############################################################################### +# Build listing object +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + sort_cols = sort_cols, + disp_cols = disp_cols, + round_type = "sas" +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(21, 38, 51, 73, 22, 19, 19, 19, 22) + +tt_to_tlgrtf( + head(result, 100), + file = fileid, + orientation = "landscape" +) diff --git a/tests/testthat/source_code/lsfvit01.R b/tests/testthat/source_code/lsfvit01.R index a96ef314..f195c154 100644 --- a/tests/testthat/source_code/lsfvit01.R +++ b/tests/testthat/source_code/lsfvit01.R @@ -1,30 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfvit01.R -## R version: 4.2.1 -## Short Description: Create LSFVIT01: Listing of Subjects With -## Treatment-emergent Clinically Important Vital -## Signs -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-24 -## Input: ADVS -## Output: lsfvit01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -44,7 +17,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2", "COL3") -disp_cols <- paste0("COL", 0:9) +sort_cols <- c("COL0", "COL1", "COL2", "COL3") +disp_cols <- paste0("COL", 0:11) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -52,17 +26,61 @@ tab_titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) +# Parameters to be included by default +param_cds <- c("SYSBP", "DIABP", "PULSE", "RESP", "TEMP", "WEIGHT", "HEIGHT") ############################################################################### # Process data ############################################################################### -advs <- advs_jnj %>% - filter(!!rlang::sym(popfl) == "Y") +advs <- advs_jnj |> + filter(!!rlang::sym(popfl) == "Y" & PARAMCD %in% param_cds) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + PARAM = factor( + .data$PARAM, + levels = unique(.data[["PARAM"]])[order(unique(.data[["PARAMN"]]))] + ), + AVISIT = factor( + .data[["AVISIT"]], + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) -advs_crit <- advs %>% - filter(CRIT1FL == "Y" | CRIT2FL == "Y" | CRIT3FL == "Y") %>% - select(STUDYID, USUBJID, PARAMCD) %>% +advs_crit <- advs |> + filter(CRIT7FL == "Y" | CRIT8FL == "Y") |> + select(STUDYID, USUBJID, PARAMCD) |> distinct() advs_dig <- tidytlg:::make_precision_data( @@ -70,10 +88,10 @@ advs_dig <- tidytlg:::make_precision_data( decimal = 4, precisionby = "PARAMCD", precisionon = "AVAL" -) %>% +) |> rename(c(VALDIGMAX = "decimal")) -advs_list <- advs_crit %>% +advs_list <- advs_crit |> inner_join( advs, by = c( @@ -81,14 +99,14 @@ advs_list <- advs_crit %>% "USUBJID" = "USUBJID", "PARAMCD" = "PARAMCD" ) - ) %>% + ) |> inner_join(advs_dig, by = c("PARAMCD" = "PARAMCD")) -lsting <- advs_list %>% +lsting <- advs_list |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), ADT = ifelse( nchar(as.character(ADT)) == 10, toupper(format(ADT, "%d%b%Y")), @@ -98,18 +116,12 @@ lsting <- advs_list %>% ADYN = ifelse(!is.na(ADY), ADY, NA), ADY = ifelse(!is.na(ADY), ADY, "--"), VAL_RES = case_when( - is.na(VALDIGMAX) & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 0 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 1 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL), - VALDIGMAX == 2 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 2, as_char = TRUE, na_char = NULL), - VALDIGMAX == 3 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 3, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 4 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 4, as_char = TRUE, na_char = NULL), + is.na(VALDIGMAX) & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 0 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 1 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL), + VALDIGMAX == 2 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 2, as_char = TRUE, na_char = NULL), + VALDIGMAX == 3 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 3, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 4 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 4, as_char = TRUE, na_char = NULL), !is.na(AVALC) ~ AVALC ), VAL_HL = case_when( @@ -121,59 +133,50 @@ lsting <- advs_list %>% !is.na(VAL_RES) & is.na(VAL_HL) ~ VAL_RES, .default = NA ), - CRIT1L = ifelse(CRIT1FL == "Y", as.character(CRIT1), NA), - CRIT2L = ifelse(CRIT2FL == "Y", as.character(CRIT2), NA), - CRIT3L = ifelse(CRIT3FL == "Y", as.character(CRIT3), NA) - ) %>% + CRIT7L = ifelse(CRIT7FL == "Y", as.character(CRIT7), NA), + CRIT8L = ifelse(CRIT8FL == "Y", as.character(CRIT8), NA) + ) |> unite( "CRITL", - CRIT1L, - CRIT2L, - CRIT3L, + CRIT7L, + CRIT8L, sep = ", ", na.rm = TRUE, remove = FALSE - ) %>% + ) |> mutate( COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), COL3 = explicit_na(PARAM, ""), # Optional Variable: ATM COL4 = case_when( ADT == "" ~ "", - ADT != "" & ATM != "" & ADY != "" ~ - paste0(ADT, concat_sep, ATM, " (", ADY, ")"), - ADT != "" & ATM == "" & ADY != "" ~ - paste0(ADT, concat_sep, "--:--", " (", ADY, ")"), - ADT != "" & ATM != "" & ADY == "" ~ - paste0(ADT, concat_sep, ATM, " (-)"), - ADT != "" & ATM == "" & ADY == "" ~ - paste0(ADT, concat_sep, "--:--", " (-)"), + ADT != "" & ATM != "" & ADY != "" ~ paste0(ADT, concat_sep, ATM, " (", ADY, ")"), + ADT != "" & ATM == "" & ADY != "" ~ paste0(ADT, concat_sep, "--:--", " (", ADY, ")"), + ADT != "" & ATM != "" & ADY == "" ~ paste0(ADT, concat_sep, ATM, " (-)"), + ADT != "" & ATM == "" & ADY == "" ~ paste0(ADT, concat_sep, "--:--", " (-)"), ), COL5 = explicit_na(AVISIT, ""), # Optional Column: COL6/ATPT - COL6 = explicit_na(ATPT, ""), + COL6 = explicit_na(stringr::str_to_sentence(ATPT), ""), COL7 = VAL, - COL8 = case_when( + COL8 = explicit_na(VSCLSIG, ""), + COL9 = case_when( is.na(CHG) ~ "", is.na(VALDIGMAX) & !is.na(AVAL) & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 0 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 1 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 1, as_char = TRUE, na_char = NULL), - VALDIGMAX == 2 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 2, as_char = TRUE, na_char = NULL), - VALDIGMAX == 3 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 3, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 4 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 4, as_char = TRUE, na_char = NULL) + VALDIGMAX == 0 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 1 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 1, as_char = TRUE, na_char = NULL), + VALDIGMAX == 2 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 2, as_char = TRUE, na_char = NULL), + VALDIGMAX == 3 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 3, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 4 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 4, as_char = TRUE, na_char = NULL) ), # Optional Column: COL9/CRITy/ATOXGR - COL9 = explicit_na(CRITL, ""), - # COL9 = explicit_na(ATOXGR, ""), - ) %>% + COL10 = explicit_na(CRITL, ""), + # COL10 = explicit_na(ATOXGR, ""), + COL11 = explicit_na(TRTEMFL, "") + ) |> arrange(COL0, COL1, COL2, COL3, !is.na(ADYN), ADYN, ADTM) lsting <- var_relabel( @@ -192,13 +195,14 @@ lsting <- var_relabel( # Optional Column: COL6/ATPT COL6 = "Time Point", COL7 = "Result", - COL8 = "Change From Baseline", - # Optional Column: COL9/CRITy/ATOXGR - COL9 = "Criteria" - # COL9 = "Grade" + COL8 = "Clinically Significant?", + COL9 = "Change From Baseline", + # Optional Column: COL10/CRITy/ATOXGR + # COL10 = "Grade" + COL10 = "Criteria", + COL11 = "Treatment-emergent?" ) - ############################################################################### # Build listing ############################################################################### @@ -206,7 +210,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + sort_cols = sort_cols, + disp_cols = disp_cols, + round_type = "sas" ) ############################################################################### @@ -219,6 +225,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 18, 20, 74, 18, 75, 12, 15, 19) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 18, 23, 43, 18, 17, 12, 21, 15, 64, 18) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsfvit02.R b/tests/testthat/source_code/lsfvit02.R index 02bd24a1..078209e9 100644 --- a/tests/testthat/source_code/lsfvit02.R +++ b/tests/testthat/source_code/lsfvit02.R @@ -1,28 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsfvit02.R -## R version: 4.2.1 -## Short Description: Create LSFVIT02: Listing of Vital Signs -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-09-12 -## Input: ADVS -## Output: lsfvit02.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -41,7 +16,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2", "COL3") -disp_cols <- paste0("COL", 0:9) +sort_cols <- c("COL0", "COL1", "COL2", "COL3") +disp_cols <- paste0("COL", 0:11) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -49,30 +25,74 @@ tab_titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) +# Parameters to be included by default +param_cds <- c("SYSBP", "DIABP", "PULSE", "RESP", "TEMP", "WEIGHT", "HEIGHT") ############################################################################### # Process data ############################################################################### -advs <- advs_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & PARAMCD != "VSALL") +advs <- advs_jnj |> + filter(!!rlang::sym(popfl) == "Y" & PARAMCD %in% param_cds) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + PARAM = factor( + .data$PARAM, + levels = unique(.data[["PARAM"]])[order(unique(.data[["PARAMN"]]))] + ), + AVISIT = factor( + .data[["AVISIT"]], + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) advs_dig <- tidytlg:::make_precision_data( df = advs, decimal = 4, precisionby = "PARAMCD", precisionon = "AVAL" -) %>% +) |> rename(c(VALDIGMAX = "decimal")) -advs_list <- advs %>% +advs_list <- advs |> inner_join(advs_dig, by = c("PARAMCD" = "PARAMCD")) -lsting <- advs_list %>% +lsting <- advs_list |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), ADT = ifelse( nchar(as.character(ADT)) == 10, toupper(format(ADT, "%d%b%Y")), @@ -82,18 +102,12 @@ lsting <- advs_list %>% ADYN = ifelse(!is.na(ADY), ADY, NA), ADY = ifelse(!is.na(ADY), ADY, "--"), VAL_RES = case_when( - is.na(VALDIGMAX) & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 0 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 1 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL), - VALDIGMAX == 2 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 2, as_char = TRUE, na_char = NULL), - VALDIGMAX == 3 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 3, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 4 & !is.na(AVAL) ~ - tidytlg::roundSAS(AVAL, digits = 4, as_char = TRUE, na_char = NULL), + is.na(VALDIGMAX) & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 0 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 1 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 1, as_char = TRUE, na_char = NULL), + VALDIGMAX == 2 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 2, as_char = TRUE, na_char = NULL), + VALDIGMAX == 3 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 3, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 4 & !is.na(AVAL) ~ tidytlg::roundSAS(AVAL, digits = 4, as_char = TRUE, na_char = NULL), !is.na(AVALC) ~ AVALC ), VAL_HL = case_when( @@ -105,59 +119,50 @@ lsting <- advs_list %>% !is.na(VAL_RES) & is.na(VAL_HL) ~ VAL_RES, .default = NA ), - CRIT1L = ifelse(CRIT1FL == "Y", as.character(CRIT1), NA), - CRIT2L = ifelse(CRIT2FL == "Y", as.character(CRIT2), NA), - CRIT3L = ifelse(CRIT3FL == "Y", as.character(CRIT3), NA) - ) %>% + CRIT7L = ifelse(CRIT7FL == "Y", as.character(CRIT7), NA), + CRIT8L = ifelse(CRIT8FL == "Y", as.character(CRIT8), NA) + ) |> unite( "CRITL", - CRIT1L, - CRIT2L, - CRIT3L, + CRIT7L, + CRIT8L, sep = ", ", na.rm = TRUE, remove = FALSE - ) %>% + ) |> mutate( COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), COL3 = explicit_na(PARAM, ""), # Optional Variable: ATM COL4 = case_when( ADT == "" ~ "", - ADT != "" & ATM != "" & ADY != "" ~ - paste0(ADT, concat_sep, ATM, " (", ADY, ")"), - ADT != "" & ATM == "" & ADY != "" ~ - paste0(ADT, concat_sep, "--:--", " (", ADY, ")"), - ADT != "" & ATM != "" & ADY == "" ~ - paste0(ADT, concat_sep, ATM, " (-)"), - ADT != "" & ATM == "" & ADY == "" ~ - paste0(ADT, concat_sep, "--:--", " (-)"), + ADT != "" & ATM != "" & ADY != "" ~ paste0(ADT, concat_sep, ATM, " (", ADY, ")"), + ADT != "" & ATM == "" & ADY != "" ~ paste0(ADT, concat_sep, "--:--", " (", ADY, ")"), + ADT != "" & ATM != "" & ADY == "" ~ paste0(ADT, concat_sep, ATM, " (-)"), + ADT != "" & ATM == "" & ADY == "" ~ paste0(ADT, concat_sep, "--:--", " (-)"), ), COL5 = explicit_na(AVISIT, ""), # Optional Column: COL6/ATPT - COL6 = explicit_na(ATPT, ""), + COL6 = explicit_na(stringr::str_to_sentence(ATPT), ""), COL7 = VAL, - COL8 = case_when( + COL8 = explicit_na(VSCLSIG, ""), + COL9 = case_when( is.na(CHG) ~ "", is.na(VALDIGMAX) & !is.na(AVAL) & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 0 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), - VALDIGMAX == 1 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 1, as_char = TRUE, na_char = NULL), - VALDIGMAX == 2 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 2, as_char = TRUE, na_char = NULL), - VALDIGMAX == 3 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 3, as_char = TRUE, na_char = NULL), - VALDIGMAX >= 4 & !is.na(CHG) ~ - tidytlg::roundSAS(CHG, digits = 4, as_char = TRUE, na_char = NULL) + VALDIGMAX == 0 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 0, as_char = TRUE, na_char = NULL), + VALDIGMAX == 1 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 1, as_char = TRUE, na_char = NULL), + VALDIGMAX == 2 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 2, as_char = TRUE, na_char = NULL), + VALDIGMAX == 3 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 3, as_char = TRUE, na_char = NULL), + VALDIGMAX >= 4 & !is.na(CHG) ~ tidytlg::roundSAS(CHG, digits = 4, as_char = TRUE, na_char = NULL) ), # Optional Column: COL9/CRITy/ATOXGR - COL9 = explicit_na(CRITL, ""), - # COL9 = explicit_na(ATOXGR, ""), - ) %>% + COL10 = explicit_na(CRITL, ""), + # COL10 = explicit_na(ATOXGR, ""), + COL11 = explicit_na(TRTEMFL, "") + ) |> arrange(COL0, COL1, COL2, COL3, !is.na(ADYN), ADYN, ADTM) lsting <- var_relabel( @@ -176,10 +181,12 @@ lsting <- var_relabel( # Optional Column: COL6/ATPT COL6 = "Time Point", COL7 = "Result", - COL8 = "Change From Baseline", - # Optional Column: COL9/CRITy/ATOXGR - COL9 = "Criteria" - # COL9 = "Grade" + COL8 = "Clinically Significant?", + COL9 = "Change From Baseline", + # Optional Column: COL10/CRITy/ATOXGR + COL10 = "Criteria", + # COL10 = "Grade", + COL11 = "Treatment-emergent?" ) ############################################################################### @@ -189,7 +196,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + sort_cols = sort_cols, + disp_cols = disp_cols, + round_type = "sas" ) ############################################################################### @@ -198,10 +207,23 @@ result <- rlistings::as_listing( result <- set_titles(result, tab_titles) -colwidth <- c(21, 13, 18, 31, 74, 18, 50, 26, 15, 19) +############################################################################### +# Output listing +############################################################################### +# If resulting Listing output is too large of a file (>20MB) then the listing +# should be split into multiple parts +# The split below is based on the treatment groups +# Update as-needed for your study +# Remove head(n = 500) from code below as this was included to only display a +# subset of an extremely large test dataset +result1 <- result |> + filter(toupper(.data[[trtvar]]) == "XANOMELINE LOW DOSE") |> + head(n = 500) + + +colwidth <- c(21, 13, 18, 24, 75, 15, 29, 22, 21, 15, 14, 18) tt_to_tlgrtf( - colwidths = colwidth, head(result, 100), file = paste0(fileid), orientation = "landscape" diff --git a/tests/testthat/source_code/lsicm01.R b/tests/testthat/source_code/lsicm01.R index de98a2d2..0ff9f21e 100644 --- a/tests/testthat/source_code/lsicm01.R +++ b/tests/testthat/source_code/lsicm01.R @@ -1,28 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsicm01.R -## R version: 4.2.1 -## Short Description: Create LSICM01: Listing of Medications -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-17 -## Input: ADCM -## Output: lsicm01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -40,6 +15,7 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1") +sort_cols <- c("COL0", "COL1", "ASTDT") disp_cols <- paste0("COL", 0:11) concat_sep <- " / " tab_titles <- list( @@ -48,37 +24,68 @@ tab_titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) +# CM ATC levels - User input parameter to specify which ATC levels to include in the listing +atclvls <- c("CMLVL1", "CMLVL2") + +# User input parameter to specify Base Preferred Term or Standardized Medication Name to include in the listing +medname_var <- c("CMDECOD") # Standardized Medication Name or/and Base Preferred Term + +medname_label <- ifelse( + length(medname_var) > 1, + paste(c("Standardized Medication Name", "Base Preferred Term"), collapse = concat_sep), + ifelse(medname_var == "CMBASPRF", "Base Preferred Term", "Standardized Medication Name") +) ############################################################################### # Process data ############################################################################### -adcm <- adcm_jnj %>% +adcm <- adcm_jnj |> filter( !!rlang::sym(popfl) == "Y" & ((CMPRESP == "Y" & CMOCCUR == "Y") | (is.na(CMPRESP))) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) ) -lsting <- adcm %>% +lsting <- adcm |> # Update CQzzNAM variabes based on study requirements unite( "CQNAM", - CQ01NAM, - CQ02NAM, - CQ03NAM, - CQ04NAM, - CQ05NAM, - CQ06NAM, - CQ07NAM, + starts_with("CQ"), sep = ", ", na.rm = TRUE, remove = FALSE - ) %>% - mutate(across( - c(CMLVL1:CMLVL4, CMTRT, CMDECOD, CMDOSFRQ, CMROUTE, CMINDCSP), - ~ ifelse(. == "", "-", as.character(.)) - )) %>% + ) |> + mutate( + across( + c(CMTRT, CMDOSFRQ, CMROUTE, CMINDCSP), + ~ ifelse(. == "", "-", as.character(.)) + ), + across( + c(all_of(atclvls)), + ~ case_when( + .x == "" ~ "Uncoded", + .default = .x + ) + ), + across( + c(CMDECOD, CMBASPRF), + ~ case_when( + .x == "" ~ paste0("Uncoded: ", CMTRT), + .default = .x + ) + ), + across( + all_of(atclvls), + ~ stringr::str_to_sentence(.x) + ) + ) |> mutate( CMSTDT = as.Date(CMSTDTC, format = "%Y-%m-%d"), CMSTYR = ifelse( @@ -132,7 +139,7 @@ lsting <- adcm %>% PREFLL = ifelse(is.na(PREFL), NA, "P"), ONTRTFLL = ifelse(is.na(ONTRTFL), NA, "C"), FUPFLL = ifelse(is.na(FUPFL), NA, "F") - ) %>% + ) |> unite( "CMSTDTL", CMSTDAY, @@ -141,7 +148,7 @@ lsting <- adcm %>% sep = "", na.rm = TRUE, remove = FALSE - ) %>% + ) |> unite( "CMENDTL", CMENDAY, @@ -150,7 +157,7 @@ lsting <- adcm %>% sep = "", na.rm = TRUE, remove = FALSE - ) %>% + ) |> unite( "POF", PREFLL, @@ -159,20 +166,16 @@ lsting <- adcm %>% sep = ";", na.rm = TRUE, remove = FALSE - ) %>% + ) |> mutate( STDATE = case_when( - CMSTDTL != "" & CMSTDYL != "" ~ - paste0(toupper(CMSTDTL), " (", CMSTDYL, ")"), - CMSTDTL != "" & CMSTDYL == "" ~ - paste0(toupper(CMSTDTL), ""), + CMSTDTL != "" & CMSTDYL != "" ~ paste0(toupper(CMSTDTL), " (", CMSTDYL, ")"), + CMSTDTL != "" & CMSTDYL == "" ~ paste0(toupper(CMSTDTL), ""), TRUE ~ "" ), ENDATE = case_when( - CMENDTL != "" & CMENDYL != "" ~ - paste0(toupper(CMENDTL), " (", CMENDYL, ")"), - CMENDTL != "" & CMENDYL == "" ~ - paste0(toupper(CMENDTL), ""), + CMENDTL != "" & CMENDYL != "" ~ paste0(toupper(CMENDTL), " (", CMENDYL, ")"), + CMENDTL != "" & CMENDYL == "" ~ paste0(toupper(CMENDTL), ""), CMENDTL == "" & CMENRF == "AFTER" ~ "Ongoing", TRUE ~ "" ), @@ -183,21 +186,16 @@ lsting <- adcm %>% ), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - # Optional Variable: CMDECOD/CMBASPRF + # Common medication name variable based on user selection COL2 = paste( stringr::str_to_sentence(CMTRT), - stringr::str_to_sentence(CMDECOD), + stringr::str_to_sentence(.data[[medname_var]]), sep = concat_sep ), COL3 = explicit_na(POF, ""), # Optional Column: COL4/CQzzNAM COL4 = explicit_na(CQNAM, ""), - # Optional Variable: CMLVL1/CMLVL2/CMLVL3/CMLVL4 - COL5 = paste( - stringr::str_to_sentence(CMLVL1), - stringr::str_to_sentence(CMLVL2), - sep = concat_sep - ), + COL5 = do.call(paste, c(across(all_of(atclvls)), sep = concat_sep)), COL6 = explicit_na(STDATE, ""), COL7 = explicit_na(ENDATE, ""), COL8 = explicit_na(DOSEU, ""), @@ -205,34 +203,33 @@ lsting <- adcm %>% # Optional Column: COL10/CMROUTE COL10 = explicit_na(stringr::str_to_sentence(CMROUTE), ""), COL11 = explicit_na(CMINDCSP, "") - ) %>% + ) |> arrange(COL0, COL1, ASTDT) +atclvls_label <- sub(".*(\\d+)$", "ATC Level \\1", atclvls) |> + paste(collapse = concat_sep) + lsting <- var_relabel( lsting, COL0 = "Treatment Group", COL1 = "Subject ID", - # Optional Variable: CMDECOD/CMBASPRF - # COL2 = paste("Medication (Verbatim)", - # "Standardized Medication Name", - # sep = concat_sep), COL2 = paste( "Medication (Verbatim)", - "Base Preferred Term", + medname_label, sep = concat_sep ), - COL3 = paste("Prior", "Concomitant", sep = concat_sep), + COL3 = "Medication Timing", # Optional Column: COL4/CQzzNAM COL4 = "Interest Category", - # Optional Variable: CMLVL1/CMLVL2/CMLVL3/CMLVL4 - COL5 = paste("ATC Level 1", "ATC Level 2", sep = concat_sep), + # COL5: Based on input parameter atclvls + COL5 = atclvls_label, COL6 = "Start Date of Medication (Study Day~[super a])", COL7 = "End Date of Medication (Study Day~[super a])", COL8 = "Dose (Unit)", COL9 = "Frequency", # Optional Column: COL10/CMROUTE COL10 = "Route", - COL11 = "Indication:Specify" + COL11 = "Indication: Specify" ) ############################################################################### @@ -242,7 +239,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -255,6 +254,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 29, 22, 16, 50, 22, 22, 16, 18, 24, 31) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 39, 20, 25, 38, 22, 22, 19, 18, 19, 29) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsidem01.R b/tests/testthat/source_code/lsidem01.R index 80be4353..42ee0ef6 100644 --- a/tests/testthat/source_code/lsidem01.R +++ b/tests/testthat/source_code/lsidem01.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsidem01.R -## R version: 4.2.1 -## Short Description: Create LSIDEM01: Listing of Demographics and -## Baseline Characteristics -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-17 -## Input: ADSL -## Output: lsidem01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -40,6 +14,7 @@ fileid <- write_path(opath, tblid) popfl <- "FASFL" trtvar <- "TRT01P" key_cols <- c("COL0", "COL1") +sort_cols <- c("COL0", "COL1") disp_cols <- paste0("COL", 0:10) concat_sep <- " / " tab_titles <- list( @@ -53,21 +28,75 @@ tab_titles <- list( # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") - -lsting <- adsl %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + COUNTRY = factor( + case_when( + COUNTRY == "USA" ~ "United States", + TRUE ~ NA_character_ + ) + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + ETHNIC = factor( + case_when( + ETHNIC == "HISPANIC OR LATINO" ~ "Hispanic or Latino", + ETHNIC == "NOT HISPANIC OR LATINO" ~ "Not Hispanic or Latino", + ETHNIC == "NOT REPORTED" ~ "Not reported", + ETHNIC == "UNKNOWN" ~ "Unknown" + ), + levels = c("Hispanic or Latino", "Not Hispanic or Latino", "Not reported", "Unknown") + ) + ) + + +lsting <- adsl |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), COL2 = explicit_na(REGION1, ""), - COL3 = explicit_na(COUNTRY_DECODE, ""), + COL3 = explicit_na(COUNTRY, ""), COL4 = explicit_na(toupper(format(RFICDT, "%d%b%Y")), ""), - COL5 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - COL6 = explicit_na(ETHNIC_DECODE, ""), + COL5 = paste(AGE, SEX, RACE, sep = concat_sep), + COL6 = explicit_na(ETHNIC, ""), COL7 = explicit_na( tidytlg::roundSAS(WEIGHTBL, digits = 1, as_char = TRUE, na_char = ""), "" @@ -85,7 +114,7 @@ lsting <- adsl %>% tidytlg::roundSAS(BSABL, digits = 2, as_char = TRUE, na_char = ""), "" ), - ) %>% + ) |> arrange(COL0, COL1) lsting <- var_relabel( @@ -111,7 +140,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -124,6 +155,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 13, 67, 23, 67, 30, 13, 12, 14, 12) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 63, 16, 17, 23, 67, 17, 13, 12, 14, 12) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsidem02.R b/tests/testthat/source_code/lsidem02.R index 904fbf58..85f65e44 100644 --- a/tests/testthat/source_code/lsidem02.R +++ b/tests/testthat/source_code/lsidem02.R @@ -1,28 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsidem02.R -## R version: 4.2.1 -## Short Description: Create LSIDEM02: Randomization Listing -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-17 -## Input: ADSL -## Output: lsidem02.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -37,7 +12,9 @@ library(junco) tblid <- "LSIDEM02" fileid <- write_path(opath, tblid) popfl <- "RANDFL" +trtvar <- "TRT01P" key_cols <- c("COL1") +sort_cols <- c("COL1") disp_cols <- paste0("COL", 1:9) concat_sep <- " / " tab_titles <- list( @@ -51,51 +28,167 @@ tab_titles <- list( # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") - -lsting <- adsl %>% +adsl <- adsl_jnj |> mutate( - COL1 = explicit_na(USUBJID, ""), - COL2 = explicit_na(REGION1, ""), - COL3 = explicit_na(COUNTRY_DECODE, ""), - COL4 = case_when( - !is.na(RANDDT) & any(names(adsl) == "RANDDTM") & !is.na(RANDDTM) ~ - paste0( - toupper(format(RANDDT, "%d%b%Y")), - concat_sep, - substr(RANDDTM, 12, 16) - ), - !is.na(RANDDT) & any(names(adsl) == "RANDDTM") & is.na(RANDDTM) ~ - paste0(toupper(format(RANDDT, "%d%b%Y")), concat_sep, "--:--"), - !is.na(RANDDT) & !any(names(adsl) == "RANDDTM") ~ - paste0(toupper(format(RANDDT, "%d%b%Y"))), + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) ), - COL5 = explicit_na(RANUM, ""), - # Optional Column: COL6/STRAT1R - COL6 = explicit_na(STRAT1R, ""), - # Optional Column: COL7/STRAT2R - COL7 = explicit_na(STRAT2R, ""), - COL8 = explicit_na(TRT01P, ""), - COL9 = explicit_na(TRT01A, "") - ) %>% + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + COUNTRY = factor( + case_when( + COUNTRY == "USA" ~ "United States", + TRUE ~ NA_character_ + ) + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + ETHNIC = factor( + case_when( + ETHNIC == "HISPANIC OR LATINO" ~ "Hispanic or Latino", + ETHNIC == "NOT HISPANIC OR LATINO" ~ "Not Hispanic or Latino", + ETHNIC == "NOT REPORTED" ~ "Not reported", + ETHNIC == "UNKNOWN" ~ "Unknown" + ), + levels = c("Hispanic or Latino", "Not Hispanic or Latino", "Not reported", "Unknown") + ) + ) |> + filter(!!rlang::sym(popfl) == "Y") + +# To determine the count of STRAT variables and it's expressions programmatically +# Identify the STRAT columns +strat_cols <- grep("^STRAT\\d+R$", names(adsl), value = TRUE) + +# Sort them in numeric order +strat_cols <- strat_cols[order(as.numeric(gsub("\\D", "", strat_cols)))] + +# To build expressions for STRAT vars +strat_expr <- lapply(strat_cols, function(x) { + expr(explicit_na(!!sym(x), "")) +}) + +# To build fixed expression of mutate for fixed columns +fixed_expr <- list( + # col1 + expr(explicit_na(USUBJID, "")), + # col2 + expr(explicit_na(REGION1, "")), + # col3 + expr(explicit_na(COUNTRY, "")), + # col4 + expr(case_when( + !is.na(RANDDT) & any(names(adsl) == "RANDDTM") & !is.na(RANDDTM) ~ + paste0( + toupper(format(RANDDT, "%d%b%Y")), + concat_sep, + substr(RANDDTM, 12, 16) + ), + !is.na(RANDDT) & any(names(adsl) == "RANDDTM") & is.na(RANDDTM) ~ + paste0(toupper(format(RANDDT, "%d%b%Y")), concat_sep, "--:--"), + !is.na(RANDDT) & !any(names(adsl) == "RANDDTM") ~ paste0(toupper(format(RANDDT, "%d%b%Y"))), + )), + # col5 + expr(explicit_na(RANUM, "")) +) + +# final list including the STRAT columns +expr_list <- c(fixed_expr, strat_expr) + +# assign dynamic column names and define end col number +names(expr_list) <- paste0("COL", seq(from = 1, length.out = length(expr_list))) + +# end of STRAT col number to assign next coloumn name dynamically +end_num <- length(expr_list) + +# Adding last two variables expressions based on end STRAT COL number +expr_list[[paste0("COL", end_num + 1)]] <- expr(explicit_na(TRT01P, "")) +expr_list[[paste0("COL", end_num + 2)]] <- expr(explicit_na(TRT01A, "")) + +# Adding COL names and it's expressions +lsting <- adsl |> + mutate(!!!expr_list) |> arrange(COL1) -lsting <- var_relabel( - lsting, - COL1 = "Subject ID", - COL2 = "Region", - COL3 = paste("Country", "Territory", sep = concat_sep), - COL4 = paste("Randomization Date", "Time", sep = concat_sep), - COL5 = "Randomization Number", - # Optional Column: COL6/STRAT1R - COL6 = "Stratification Factor 1", - # Optional Column: COL7/STRAT2R - COL7 = "Stratification Factor 2", - COL8 = "Randomization Treatment Assignment", - COL9 = "Actual Treatment" +# To create a list of variables and it's labels programmatically to include in the output +# list of COL names +col_names <- colnames(lsting)[grep("^COL\\d+$", colnames(lsting))] + +# Fixed COL labels +fixed_labels <- c( + # col1 + "Subject ID", + # col2 + "Region", + # col3 + paste("Country", "Territory", sep = concat_sep), + # col4 + paste("Randomization Date", "Time", sep = concat_sep), + # col5 + "Randomization Number" +) + +# To pull labels of STRATxD variables from ADSL +stratd_cols <- sub(".$", "D", strat_cols) + +strat_labels <- setNames( + lapply(stratd_cols, function(str) { + lbl <- attr(adsl[[str]], "label") + + if (is.null(lbl) || is.na(lbl) || lbl == "") { + str + } else { + lbl + } + }), + stratd_cols +) + +# End fixed column labels +end_labels <- c( + "Randomization Treatment Assignment", + "Actual Treatment" ) +# All labels +all_labels <- c(fixed_labels, strat_labels, end_labels) + +# COL and Label list +label_list <- as.list(setNames(all_labels, col_names)) + +# Adding COL names and it's labels +for (nm in names(label_list)) { + attr(lsting[[nm]], "label") <- label_list[[nm]] +} + ############################################################################### # Build listing ############################################################################### @@ -103,7 +196,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = c("COL1"), - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -116,6 +211,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(63, 13, 42, 47, 26, 22, 22, 26, 21) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(25, 16, 17, 26, 26, 72, 48, 26, 21) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsidev01.R b/tests/testthat/source_code/lsidev01.R new file mode 100644 index 00000000..6aa9e124 --- /dev/null +++ b/tests/testthat/source_code/lsidev01.R @@ -0,0 +1,135 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) +library(stringi) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LSIDEV01" +fileid <- write_path(opath, tblid) +popfl <- "FASFL" +trtvar <- "TRT01A" +key_cols <- c("COL0", "COL1", "COL2", "COL3", "COL4", "COL5") +sort_cols <- c("COL0", "COL1", "COL2", "COL3", "COL4", "COL5") +disp_cols <- paste0("COL", 0:8) +concat_sep <- " / " +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +############################################################################### +# Process data +############################################################################### + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) + +dv <- dv_jnj |> + filter(toupper(DVCAT) == "MAJOR") |> + select(STUDYID, USUBJID, DVSEQ, DVDECOD, DVTERM, DVSTDTC, DVDECOD) |> + mutate( + DVSTDT = as.Date(DVSTDTC), + ) + +lsting <- adsl |> + dplyr::inner_join(dv, by = c("STUDYID", "USUBJID")) |> + mutate( + AGE = explicit_na(as.character(AGE), ""), + SEX = explicit_na(SEX, ""), + RACE = explicit_na(RACE, ""), + DVDECOD = explicit_na(DVDECOD, ""), + DVTERM = explicit_na(DVTERM, ""), + COL0 = explicit_na(REGION1, ""), + COL1 = explicit_na(SITEID, ""), + COL2 = explicit_na(.data[[trtvar]], ""), + COL3 = explicit_na(USUBJID, ""), + COL4 = paste(AGE, SEX, RACE, sep = concat_sep), + COL5 = explicit_na(as.character(DVSTDT)), + COL6 = as.integer(DVSTDT - TRTSDT + (DVSTDT >= TRTSDT)), + COL7 = explicit_na(DVDECOD), + COL8 = explicit_na(DVTERM) + ) |> + arrange(COL0, COL1, COL2, COL3, COL4, COL5) + + +lsting <- var_relabel( + lsting, + COL0 = "Region", + COL1 = "Site ID", + COL2 = "Treatment Group", + COL3 = "Subject ID", + COL4 = paste("Age (years)", "Sex", "Race", sep = concat_sep), + COL5 = "Start Date of Deviation", + COL6 = "Study Day~[super a] of Start of Deviation", + COL7 = "Protocol Deviation Category", + COL8 = "Protocol Deviation Verbatim Term" +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(16, 8, 21, 13, 49, 17, 19, 71, 71) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsidev02.R b/tests/testthat/source_code/lsidev02.R new file mode 100644 index 00000000..50954fe6 --- /dev/null +++ b/tests/testthat/source_code/lsidev02.R @@ -0,0 +1,135 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) +library(stringi) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LSIDEV02" +fileid <- write_path(opath, tblid) +popfl <- "FASFL" +trtvar <- "TRT01A" +key_cols <- c("COL0", "COL1", "COL2", "COL3", "COL4", "COL5") +sort_cols <- c("COL0", "COL1", "COL2", "COL3", "COL4", "COL5") +disp_cols <- paste0("COL", 0:8) +concat_sep <- " / " +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +############################################################################### +# Process data +############################################################################### + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) + +dv <- dv_jnj |> + filter(tolower(DVDECOD) == "received wrong treatment or incorrect dose") |> + select(STUDYID, USUBJID, DVSEQ, DVDECOD, DVTERM, DVSTDTC, DVDECOD) |> + mutate( + DVSTDT = as.Date(DVSTDTC), + ) + +lsting <- adsl |> + dplyr::inner_join(dv, by = c("STUDYID", "USUBJID")) |> + mutate( + AGE = explicit_na(as.character(AGE), ""), + SEX = explicit_na(SEX, ""), + RACE = explicit_na(RACE, ""), + DVDECOD = explicit_na(DVDECOD, ""), + DVTERM = explicit_na(DVTERM, ""), + COL0 = explicit_na(REGION1, ""), + COL1 = explicit_na(SITEID, ""), + COL2 = explicit_na(.data[[trtvar]], ""), + COL3 = explicit_na(USUBJID, ""), + COL4 = paste(AGE, SEX, RACE, sep = concat_sep), + COL5 = explicit_na(as.character(DVSTDT)), + COL6 = as.integer(DVSTDT - TRTSDT + (DVSTDT >= TRTSDT)), + COL7 = explicit_na(DVDECOD), + COL8 = explicit_na(DVTERM) + ) |> + arrange(COL0, COL1, COL2, COL3, COL4, COL5) + + +lsting <- var_relabel( + lsting, + COL0 = "Region", + COL1 = "Site ID", + COL2 = "Treatment Group", + COL3 = "Subject ID", + COL4 = paste("Age (years)", "Sex", "Race", sep = concat_sep), + COL5 = "Start Date of Deviation", + COL6 = "Study Day~[super a] of Start of Deviation", + COL7 = "Protocol Deviation Category", + COL8 = "Protocol Deviation Verbatim Term" +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(16, 8, 21, 13, 54, 20, 19, 67, 67) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsidev03.R b/tests/testthat/source_code/lsidev03.R new file mode 100644 index 00000000..457f81dd --- /dev/null +++ b/tests/testthat/source_code/lsidev03.R @@ -0,0 +1,126 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(rlistings) +library(junco) +library(stringi) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LSIDEV03" +fileid <- write_path(opath, tblid) +popfl <- "FASFL" +trtvar <- "TRT01A" +key_cols <- c("COL0", "COL1", "COL2", "COL3") +sort_cols <- c("COL0", "COL1", "COL2", "COL3") +disp_cols <- paste0("COL", 0:6) +concat_sep <- " / " +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +############################################################################### +# Process data +############################################################################### + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) + +ie <- ie_jnj |> + select(STUDYID, USUBJID, IETESTCD, IETEST) + +lsting <- adsl |> + dplyr::inner_join(ie, by = c("STUDYID", "USUBJID")) |> + mutate( + AGE = explicit_na(as.character(AGE), ""), + SEX = explicit_na(SEX, ""), + RACE = explicit_na(RACE, ""), + IETESTCD = explicit_na(IETESTCD, ""), + IETEST = explicit_na(IETEST, ""), + COL0 = explicit_na(REGION1, ""), + COL1 = explicit_na(SITEID, ""), + COL2 = explicit_na(.data[[trtvar]], ""), + COL3 = explicit_na(USUBJID, ""), + COL4 = paste(AGE, SEX, RACE, sep = concat_sep), + COL5 = explicit_na(IETESTCD), + COL6 = explicit_na(IETEST) + ) |> + arrange(COL0, COL1, COL2, COL3) + + +lsting <- var_relabel( + lsting, + COL0 = "Region", + COL1 = "Site ID", + COL2 = "Treatment Group", + COL3 = "Subject ID", + COL4 = paste("Age (years)", "Sex", "Race", sep = concat_sep), + COL5 = paste("Inclusion", "Exclusion Criterion Number", sep = concat_sep), + COL6 = paste("Inclusion", "Exclusion Description", sep = concat_sep) +) + +############################################################################### +# Build listing +############################################################################### + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(16, 8, 21, 63, 67, 29, 70) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsids01.R b/tests/testthat/source_code/lsids01.R index 686d7261..63c6fd63 100644 --- a/tests/testthat/source_code/lsids01.R +++ b/tests/testthat/source_code/lsids01.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsids01.R -## R version: 4.2.1 -## Short Description: Create LSIDS01: Listing of Subjects Who -## Permanently Discontinued Treatment -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-08 -## Input: ADSL, DS -## Output: lsids01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -40,6 +14,7 @@ fileid <- write_path(opath, tblid) popfl <- "FASFL" trtvar <- "TRT01P" key_cols <- c("COL0", "COL1") +sort_cols <- c("COL0", "COL1", "COL2", "COL3") disp_cols <- paste0("COL", 0:8) concat_sep <- " / " tab_titles <- list( @@ -53,22 +28,63 @@ tab_titles <- list( # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & !(EOTSTT %in% c("COMPLETED", "ONGOING"))) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y" & !(EOTSTT %in% c("COMPLETED", "ONGOING"))) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male" + ), + levels = c("Female", "Male") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) -ds <- ds_jnj %>% +ds <- ds_jnj |> filter( (DSSCAT %in% c("TREATMENT")) & DSCAT == "DISPOSITION EVENT" & DSDECOD != "COMPLETED" - ) %>% + ) |> select(STUDYID, USUBJID, DSSCAT) -adsl_ds <- adsl %>% +adsl_ds <- adsl |> left_join(ds, by = c("STUDYID" = "STUDYID", "USUBJID" = "USUBJID")) -adexsum <- adexsum_jnj %>% - filter(PARAMCD == "CUMDOSE") %>% +adexsum <- adexsum_jnj |> + filter(PARAMCD == "CUMDOSE") |> select(STUDYID, USUBJID, PARAMCD, PARAM, AVAL) adsl_ds_adexsum <- left_join( @@ -80,28 +96,30 @@ adsl_ds_adexsum <- left_join( ) ) -lsting <- adsl_ds_adexsum %>% +lsting <- adsl_ds_adexsum |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), AVAL = explicit_na(as.character(AVAL), ""), AVALU = case_when( - !is.na(AVAL) ~ - stringr::str_extract(PARAM, "(?<=\\()([^()]*?)(?=\\)[^()]*$)"), - is.na(AVAL) ~ - "" + !is.na(AVAL) ~ stringr::str_extract(PARAM, "(?<=\\()([^()]*?)(?=\\)[^()]*$)"), + is.na(AVAL) ~ "" ), DCTREAS = explicit_na(DCTREAS, ""), DCTREASP = explicit_na(DCTREASP, ""), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), # Optional Column: COL3/DSSCAT COL3 = explicit_na(stringr::str_to_sentence(DSSCAT), ""), # Optional Column: COL4/LTVISIT COL4 = explicit_na(LTVISIT, ""), - COL5 = explicit_na(as.character(TRTEDY), ""), + COL5 = ifelse( + is.na(TRTEDT), + "", + toupper(format(as.Date(TRTEDT), format = "%d%b%Y")) + ), # Optional Column: COL6/CUMDOSE/CUMDOSU COL6 = paste0(AVAL, " ", AVALU), COL7 = ifelse( @@ -110,14 +128,18 @@ lsting <- adsl_ds_adexsum %>% toupper(format(as.Date(DCTDT), format = "%d%b%Y")) ), COL8 = case_when( - DCTREAS == "OTHER" ~ - paste0(DCTREAS, " (", stringr::str_to_sentence(DCTREASP), ")"), - DCTREAS != "OTHER" ~ - DCTREAS + DCTREAS == "OTHER" ~ paste0(DCTREAS, " (", stringr::str_to_sentence(DCTREASP), ")"), + DCTREAS != "OTHER" ~ DCTREAS ) - ) %>% + ) |> arrange(COL0, COL1, COL2, COL3) +lsting <- lsting |> + mutate( + COL7 = ifelse(is.na(DCTADY), COL7, sprintf("%s (%s)", COL7, DCTADY)), + COL5 = ifelse(is.na(TRTEDY), COL7, sprintf("%s (%s)", COL5, TRTEDY)) + ) + lsting <- var_relabel( lsting, COL0 = "Treatment Group", @@ -127,13 +149,14 @@ lsting <- var_relabel( COL3 = "Study Agent Discontinued", # Optional Column: COL4/LTVISIT COL4 = "Last Visit~[super a]", - COL5 = "Study Day~[super b] of Last Study Agent Administered", + COL5 = "Date of Last Study Agent Administered (Study Day~[super b])", # Optional Column: COL6/CUMDOSE/CUMDOSU - COL6 = "Total Dose (unit)~[super c]", - COL7 = "Date of Discontinuation", + COL6 = "Cumulative Dose (unit)", + COL7 = "Date of Discontinuation (Study Day~[super b])", COL8 = "Primary Reason for Discontinuation" ) + ############################################################################### # Build listing ############################################################################### @@ -141,7 +164,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -154,6 +179,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 38, 67, 23, 36, 28, 18, 27, 27) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 25, 67, 23, 36, 33, 20, 33, 27) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsids02.R b/tests/testthat/source_code/lsids02.R index 10f1863c..950b3f99 100644 --- a/tests/testthat/source_code/lsids02.R +++ b/tests/testthat/source_code/lsids02.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsids02.R -## R version: 4.2.1 -## Short Description: Create LSIDS02: Listing of Subjects Who -## Discontinued Study Participation Prematurely -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-12 -## Input: ADSL -## Output: lsids02.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -37,10 +11,11 @@ library(junco) tblid <- "LSIDS02" fileid <- write_path(opath, tblid) -popfl <- "SAFFL" +popfl <- "FASFL" trtvar <- "TRT01P" key_cols <- c("COL0", "COL1") -disp_cols <- paste0("COL", 0:10) +sort_cols <- c("COL0", "COL1") +disp_cols <- paste0("COL", 0:9) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -48,68 +23,186 @@ tab_titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) +# If your data has CUMDOSE and CUMDOSSx then set cumdose_components <- TRUE +cumdose_components <- FALSE + ############################################################################### # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & EOSSTT %in% c("DISCONTINUED")) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y" & EOSSTT %in% c("DISCONTINUED")) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male" + ), + levels = c("Female", "Male") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) + +adexsum <- adexsum_jnj |> + filter(PARAMCD == "CUMDOSE" | (cumdose_components & grepl("^CUMDOSS", PARAMCD))) |> + select(STUDYID, USUBJID, PARAMCD, AVAL, PARAM) |> + tidyr::pivot_wider( + names_from = PARAMCD, + values_from = c(AVAL, PARAM), + names_glue = "{.value}_{PARAMCD}" + ) +# If your data only has CUMDOSE then this step rename AVAL to AVAL_CUMDOSE and PARAM to PARAM_CUMDOSE +# this step automatically skip if data has CUMDOSE along with CUMDOSSx +if ("AVAL" %in% names(adexsum)) { + adexsum <- rename(adexsum, AVAL_CUMDOSE = AVAL, PARAM_CUMDOSE = PARAM) +} + +adexsum <- adexsum |> + # This step convert NA to empty string ("") to align with listing + mutate( + across( + c( + starts_with("AVAL_CUMDOSE"), + starts_with("AVAL_CUMDOSS"), + starts_with("PARAM_CUMDOSE"), + starts_with("PARAM_CUMDOSS") + ), + ~ ifelse(is.na(.x), "", as.character(.x)) + ) + ) |> + # Extract the unit from PARAM_CUMDOSE + mutate( + PARAM_CUMDOSE = case_when( + !is.na(PARAM_CUMDOSE) | PARAM_CUMDOSE != "" ~ + stringr::str_extract(PARAM_CUMDOSE, "(?<=\\()([^()]*?)(?=\\)[^()]*$)"), + is.na(PARAM_CUMDOSE) | PARAM_CUMDOSE == "" ~ "" + ), + # This step extract the study agent name and unit from PARAM_CUMDOSSx and combine with AVAL_CUMDOSSx + across( + starts_with("PARAM_CUMDOSS"), + ~ { + suffix <- sub("PARAM_", "", cur_column()) + aval_col <- paste0("AVAL_", suffix) + aval <- pick(everything())[[aval_col]] + # user may need to change the pattern if they have any other value in their PARAM_CUMDOSS + agent <- trimws(ifelse( + grepl("<[^>]*>", .x), + sub(".*<([^>]*)>.*", "\\1", .x), + sub("Cumulative dose\\s+(.+?)\\s+\\(.*", "\\1", .x) + )) + unit <- trimws(ifelse( + grepl("\\[([^]]+)\\]", .x), + sub(".*\\[([^]]+)\\].*", "\\1", .x), + sub(".*\\(([^)]+)\\).*", "\\1", .x) + )) + ifelse(is.na(aval) | aval == "", "", paste0(agent, ": ", aval, " ", unit)) + }, + .names = "study_agent_{col}" + ), + # This step combine all the cumulative dose information into one column + Cum_dose = apply( + pick(everything()), + 1, + function(r) { + cumdose_part <- if ( + !is.na(r[["AVAL_CUMDOSE"]]) && + r[["AVAL_CUMDOSE"]] != "" && + !is.na(r[["PARAM_CUMDOSE"]]) && + r[["PARAM_CUMDOSE"]] != "" + ) { + paste(r[["AVAL_CUMDOSE"]], r[["PARAM_CUMDOSE"]]) + } else { + "" + } + study_parts <- unname(r[grepl("^study_agent_", names(r))]) + study_parts <- study_parts[!is.na(study_parts) & study_parts != ""] + all_parts <- c(cumdose_part, study_parts) + all_parts <- all_parts[all_parts != ""] + paste(all_parts, collapse = "; ") + } + ) + ) -adexsum <- adexsum_jnj %>% - filter(PARAMCD == "CUMDOSE") %>% - select(STUDYID, USUBJID, PARAMCD, PARAM, AVAL) adsl_adexsum <- left_join( adsl, adexsum, - by = c( - "STUDYID" = "STUDYID", - "USUBJID" = "USUBJID" - ) + by = c("STUDYID", "USUBJID") ) -lsting <- adsl_adexsum %>% +lsting <- adsl_adexsum |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), - AVAL = explicit_na(as.character(AVAL), ""), - AVALU = case_when( - !is.na(AVAL) ~ - stringr::str_extract(PARAM, "(?<=\\()([^()]*?)(?=\\)[^()]*$)"), - is.na(AVAL) ~ - "" - ), + RACE = explicit_na(RACE, ""), DCSREAS = explicit_na(DCSREAS, ""), DCSREASP = explicit_na(DCSREASP, ""), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), # Optional Column: COL3/LSVISIT COL3 = explicit_na(LSVISIT, ""), - COL4 = explicit_na(as.character(EOSDY), ""), - # Optional Column: COL5/LTVISIT - COL5 = explicit_na(LTVISIT, ""), - # Optional Column: COL6/TRTEDY - COL6 = explicit_na(as.character(TRTEDY), ""), - # Optional Column: COL7/CUMDOSE/CUMDOSU - COL7 = paste0(AVAL, " ", AVALU), - COL8 = ifelse( + # Optional Column: COL4/LTVISIT + COL4 = explicit_na(LTVISIT, ""), + # Optional Column: COL5/TRTEDT, TRTEDY + COL5 = ifelse( + is.na(TRTEDT), + "", + toupper(format(as.Date(TRTEDT), format = "%d%b%Y")) + ), + # Optional Column: COL6/CUMDOSE/CUMDOSU + COL6 = paste0(Cum_dose), + COL7 = ifelse( is.na(EOSDT), "", toupper(format(as.Date(EOSDT), format = "%d%b%Y")) ), - COL9 = case_when( - DCSREAS == "OTHER" ~ - paste0(DCSREAS, " (", stringr::str_to_sentence(DCSREASP), ")"), - DCSREAS != "OTHER" ~ - DCSREAS + COL8 = case_when( + DCSREAS == "OTHER" ~ paste0(DCSREAS, " (", stringr::str_to_sentence(DCSREASP), ")"), + DCSREAS != "OTHER" ~ DCSREAS ), - # Optional Column: COL10/UNBLNDFL - COL10 = ifelse(is.na(UNBLNDFL), "No", "Yes") - ) %>% + # Optional Column: COL9/UNBLNDFL + COL9 = ifelse(is.na(UNBLNDFL), "No", "Yes") + ) |> arrange(COL0, COL1) +lsting <- lsting |> + mutate( + COL5 = ifelse(is.na(TRTEDY), COL5, sprintf("%s (%s)", COL5, TRTEDY)), + COL7 = ifelse(is.na(EOSDY), COL7, sprintf("%s (%s)", COL7, EOSDY)) + ) + lsting <- var_relabel( lsting, COL0 = "Treatment Group", @@ -117,17 +210,17 @@ lsting <- var_relabel( COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), # Optional Column: COL3/LSVISIT COL3 = "Last Study Visit~[super a]", - COL4 = "Study Day~[super b] of Discontinuation", + # COL4 = "Study Day~[super b] of Discontinuation", # Optional Column: COL5/LTVISIT - COL5 = "Last Treatment Visit~[super c]", + COL4 = "Last Treatment Visit~[super b]", # Optional Column: COL6/TRTEDY - COL6 = "Study Day~[super b] of Last Study Agent Administered", + COL5 = "Date of Last Study Agent Administered (Study Day~[super c])", # Optional Column: COL7/CUMDOSE/CUMDOSU - COL7 = "Total Dose (unit)~[super d]", - COL8 = "Date of Discontinuation", - COL9 = "Primary Reason for Discontinuation", + COL6 = "Cumulative Dose (unit)", + COL7 = "Date of Discontinuation (Study Day~[super c])", + COL8 = "Primary Reason for Discontinuation", # Optional Column: COL10/UNBLNDFL - COL10 = "Was Blind Broken?" + COL9 = "Was Blind Broken?" ) ############################################################################### @@ -137,7 +230,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -150,6 +245,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 67, 29, 27, 18, 28, 12, 27, 27, 15) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 67, 36, 25, 33, 20, 27, 27, 15) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsids03.R b/tests/testthat/source_code/lsids03.R index 9efcf6eb..8b123888 100644 --- a/tests/testthat/source_code/lsids03.R +++ b/tests/testthat/source_code/lsids03.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsids03.R -## R version: 4.2.1 -## Short Description: Create LSIDS03: Listing of Subjects Who Were -## Unblinded During the Study -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-12 -## Input: ADSL, ADEXSUM -## Output: lsids03.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -41,6 +15,7 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01P" key_cols <- c("COL0", "COL1") +sort_cols <- c("COL0", "COL1") disp_cols <- paste0("COL", 0:9) concat_sep <- " / " tab_titles <- list( @@ -54,11 +29,52 @@ tab_titles <- list( # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & UNBLNDFL == "Y") +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y" & UNBLNDFL == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male" + ), + levels = c("Female", "Male") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) -adexsum <- adexsum_jnj %>% - filter(PARAMCD == "CUMDOSE") %>% +adexsum <- adexsum_jnj |> + filter(PARAMCD == "CUMDOSE") |> select(STUDYID, USUBJID, PARAMCD, PARAM, AVAL) adsl_adexsum <- left_join( @@ -70,27 +86,35 @@ adsl_adexsum <- left_join( ) ) -lsting <- adsl_adexsum %>% +lsting <- adsl_adexsum |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), AVAL = explicit_na(as.character(AVAL), ""), AVALU = case_when( - !is.na(AVAL) ~ - stringr::str_extract(PARAM, "(?<=\\()([^()]*?)(?=\\)[^()]*$)"), - is.na(AVAL) ~ - "" + !is.na(AVAL) ~ stringr::str_extract(PARAM, "(?<=\\()([^()]*?)(?=\\)[^()]*$)"), + is.na(AVAL) ~ "" ), EOTSTT = explicit_na(EOTSTT, ""), EOSSTT = explicit_na(EOSSTT, ""), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), # Optional Column: COL3/LTVISIT COL3 = explicit_na(LTVISIT, ""), - COL4 = explicit_na(as.character(UNBLNDDY), ""), - COL5 = explicit_na(as.character(TRTEDY), ""), + # COL4 = explicit_na(as.character(UNBLNDDY), ""), + COL4 = ifelse( + is.na(UNBLNDDT), + "", + toupper(format(as.Date(UNBLNDDT), format = "%d%b%Y")) + ), + # COL5 = explicit_na(as.character(TRTEDY), ""), + COL5 = ifelse( + is.na(TRTEDT), + "", + toupper(format(as.Date(TRTEDT), format = "%d%b%Y")) + ), # Optional Column: COL6/CUMDOSE/CUMDOSU COL6 = paste0(AVAL, " ", AVALU), COL7 = explicit_na(stringi::stri_trans_totitle(UNBREAS), ""), @@ -102,9 +126,15 @@ lsting <- adsl_adexsum %>% EOSSTT == "DISCONTINUED" ~ "Yes", EOSSTT != "DISCONTINUED" ~ "No" ) - ) %>% + ) |> arrange(COL0, COL1) +lsting <- lsting |> + mutate( + COL4 = ifelse(is.na(UNBLNDDY), COL4, sprintf("%s (%s)", COL4, UNBLNDDY)), + COL5 = ifelse(is.na(TRTEDY), COL5, sprintf("%s (%s)", COL5, TRTEDY)) + ) + lsting <- var_relabel( lsting, COL0 = "Treatment Group", @@ -112,10 +142,10 @@ lsting <- var_relabel( COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), # Optional Column: COL3/LTVISIT COL3 = "Last Visit~[super a]", - COL4 = "Study Day~[super b] of Unblinding", - COL5 = "Study Day~[super b] of Last Study Agent Administered", + COL4 = "Date of Unblinding (Study Day~[super b])", + COL5 = "Date of Last Study Agent Administered (Study Day~[super b])", # Optional Column: COL6/CUMDOSE/CUMDOSU - COL6 = "Total Dose (unit)~[super c]", + COL6 = "Cumulative Dose (unit)", COL7 = "Reason for Unblinding", COL8 = "Was Study Agent Discontinued?", COL9 = "Was Study Participation Discontinued Prematurely?" @@ -129,6 +159,8 @@ result <- rlistings::as_listing( df = lsting, key_cols = key_cols, disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -141,6 +173,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 20, 67, 33, 20, 28, 12, 20, 25, 39) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 67, 18, 23, 33, 20, 20, 25, 39) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsids04.R b/tests/testthat/source_code/lsids04.R index b5eac9d3..6eca225f 100644 --- a/tests/testthat/source_code/lsids04.R +++ b/tests/testthat/source_code/lsids04.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsids04.R -## R version: 4.2.1 -## Short Description: Create LSIDS04: Listing of Subjects Who Were -## Randomized but Never Treated -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-17 -## Input: ADSL -## Output: lsids04.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -39,6 +13,7 @@ tblid <- "LSIDS04" fileid <- write_path(opath, tblid) trtvar <- "TRT01P" key_cols <- c("COL0", "COL1") +sort_cols <- c("COL0", "COL1") disp_cols <- paste0("COL", 0:3) concat_sep <- " / " tab_titles <- list( @@ -52,20 +27,61 @@ tab_titles <- list( # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(RANDFL == "Y" & SAFFL == "N") - -lsting <- adsl %>% +adsl <- adsl_jnj |> + filter(RANDFL == "Y" & SAFFL == "N") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male" + ), + levels = c("Female", "Male") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) + +lsting <- adsl |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), # Optional Column: COL3/DCTREAS COL3 = explicit_na(DCTREAS, ""), - ) %>% + ) |> arrange(COL0, COL1) lsting <- var_relabel( @@ -74,7 +90,7 @@ lsting <- var_relabel( COL1 = "Subject ID", COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), # Optional Column: COL3/DCTREAS - COL3 = "Primary Reason for no Treatment" + COL3 = "Primary Reason Not Treated" ) ############################################################################### @@ -84,7 +100,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -97,6 +115,5 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 18, 23) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsids05.R b/tests/testthat/source_code/lsids05.R index 5f3f6dd8..719758d0 100644 --- a/tests/testthat/source_code/lsids05.R +++ b/tests/testthat/source_code/lsids05.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsids05.R -## R version: 4.2.1 -## Short Description: Create LSIDS05: Listing of Overall Study Start -## and End Dates -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-17 -## Input: ADSL -## Output: lsids05.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -39,7 +13,8 @@ tblid <- "LSIDS05" fileid <- write_path(opath, tblid) popfl <- "SCRNFL" key_cols <- c("COL1") -disp_cols <- paste0("COL", 1:3) +sort_cols <- c("COL1") +disp_cols <- paste0("COL", 1:2) tab_titles <- list( title = "Dummy Title", subtitles = NULL, @@ -50,31 +25,23 @@ tab_titles <- list( # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> summarise( rficdt_min = toupper(format(min(RFICDT, na.rm = TRUE), "%d%b%Y")), - lstsvdt_max = toupper(format(max(LSTSVDT, na.rm = TRUE), "%d%b%Y")), - rfpendtc_max = toupper(format( - max(as.Date(RFPENDTC), na.rm = TRUE), - "%d%b%Y" - )) + lstsvdt_max = toupper(format(max(LASTCTDT, na.rm = TRUE), "%d%b%Y")) ) -lsting <- adsl %>% +lsting <- adsl |> mutate( COL1 = rficdt_min, COL2 = lstsvdt_max, - # Optional Column: COL3/rfpendtc_max - COL3 = rfpendtc_max ) lsting <- var_relabel( lsting, COL1 = "First Contact in the Study~[super a]", - COL2 = "Last Visit in the Study~[super b]", - # Optional Column: COL3/rfpendtc_max - COL3 = "Last Contact in the Study~[super c]" + COL2 = "Last Contact/Visit in the Study~[super b]" ) ############################################################################### @@ -84,7 +51,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -97,6 +66,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(20, 23, 23) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(20, 23) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsiex01.R b/tests/testthat/source_code/lsiex01.R index 3f0ddac1..6d9ec74f 100644 --- a/tests/testthat/source_code/lsiex01.R +++ b/tests/testthat/source_code/lsiex01.R @@ -1,32 +1,7 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsiex01.R -## R version: 4.2.1 -## Short Description: Create LSIEX01: Listing of Study Treatment -## Administration -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-18 -## Input: ADEX -## Output: lsiex01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) +library(tidyr) library(rtables) library(rlistings) library(junco) @@ -40,7 +15,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2") -disp_cols <- paste0("COL", 0:10) +sort_cols <- c("COL0", "COL1", "COL2") +disp_cols <- paste0("COL", 0:11) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -53,14 +29,59 @@ tab_titles <- list( # Process data ############################################################################### -adex <- adex_jnj %>% - filter(!!rlang::sym(popfl) == "Y") +adex <- adex_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) -lsting <- adex %>% +lsting <- adex |> + mutate( + across(matches("^ADECOD\\d+$"), stringr::str_to_sentence) + ) |> + unite( + "decod", + matches("^ADECOD\\d+$"), + sep = ", ", + na.rm = TRUE, + remove = FALSE + ) |> mutate( + decod = ifelse(decod == "", NA, decod), AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), ASTDT = ifelse( !is.na(ASTDT) & nchar(as.character(ASTDT)) == 10, toupper(format(ASTDT, "%d%b%Y")), @@ -76,72 +97,84 @@ lsting <- adex %>% ), AENTM = ifelse(!is.na(AENDTM), substr(as.character(AENDTM), 12, 16), ""), AENDY = ifelse(!is.na(AENDY), AENDY, ""), - AREASOC = explicit_na(AREASOC, ""), - AREASOO = explicit_na(AREASOO, ""), - AADJ = explicit_na(AADJ, ""), - AADJOTH = explicit_na(AADJOTH, ""), + PRDOSE = ifelse(is.na(ASCHDOSE), "", paste(ASCHDOSE, ASCHDOSU)), + preas = case_when( + toupper(AADJP) == "ADVERSE EVENT" ~ paste0(stringr::str_to_sentence(AADJP), " (AE: ", decod, ")"), + toupper(AADJP) == "OTHER" ~ paste0(stringr::str_to_sentence(AADJP), ": ", stringr::str_to_sentence(AADJPOTH)), + !is.na(AADJP) ~ stringr::str_to_sentence(AADJP), + TRUE ~ "" + ), + dreas = case_when( + toupper(AADJ) == "ADVERSE EVENT" ~ paste0(stringr::str_to_sentence(AADJ), " (AE: ", decod, ")"), + toupper(AADJ) == "OTHER" ~ paste0(stringr::str_to_sentence(AADJ), ": ", stringr::str_to_sentence(AADJOTH)), + !is.na(AADJ) ~ stringr::str_to_sentence(AADJ), + TRUE ~ "" + ), + dly_reas = case_when( + toupper(ARSDOSD) == "OTHER" ~ paste0(stringr::str_to_sentence(ARSDOSD), ": ", stringr::str_to_sentence(ARSDSDO)), + !is.na(ARSDOSD) ~ stringr::str_to_sentence(ARSDOSD), + TRUE ~ "" + ), + ACTDOSE = ifelse(is.na(ADOSE), "", paste(ADOSE, ADOSU)), + ADOSFRQ = explicit_na(ADOSFRQ, ""), + ADOSFRQP = explicit_na(ADOSFRQP, ""), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - # Optional Column: COL3/AVISIT - COL3 = explicit_na(AVISIT, ""), - # Optional Column: COL4/ASCHDOSE/ASCHDOSU - COL4 = ifelse(is.na(ASCHDOSE), "", paste(ASCHDOSE, ASCHDOSU)), - COL5 = ifelse(is.na(ADOSE), "", paste(ADOSE, ADOSU)), - # Optional Column: COL6/ADOSFRM/ADOSFRQ/AROUTE - COL6 = paste( + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), + # Optional Column: COL3/ATPT + COL3 = explicit_na(stringr::str_to_sentence(ATPT), ""), + COL4 = paste( + PRDOSE, + ADOSFRQP, + sep = concat_sep + ), + # Optional Column: COL5/ADOSFRM/AROUTE + COL5 = paste( stringr::str_to_sentence(ADOSFRM), - ADOSFRQ, stringr::str_to_sentence(AROUTE), sep = concat_sep ), - # Optional Variable: ASTTM + # Optional Column: COL6/AACTPR/AADJP/AADJPOTH/AEDECODy(if Adverse Event) + COL6 = case_when( + !is.na(AACTPR) & preas != "" ~ paste(stringr::str_to_sentence(AACTPR), preas, sep = concat_sep), + !is.na(AACTPR) & preas == "" ~ paste(stringr::str_to_sentence(AACTPR), "", sep = concat_sep), + TRUE ~ "" + ), + # Optional column: COL7/ADOSDLY/ARSDOSD/ARSDSDO (Add when it is collected on study) COL7 = case_when( - ASTDT == "" ~ "", - ASTDT != "" & ASTTM != "" & ASTDY != "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), - ASTDT != "" & ASTTM == "" & ASTDY != "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), - ASTDT != "" & ASTTM != "" & ASTDY == "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (-)"), - ASTDT != "" & ASTTM == "" & ASTDY == "" ~ - paste0(ASTDT, concat_sep, "--:--", " (-)"), + !is.na(ADOSDLY) & dly_reas != "" ~ paste(stringr::str_to_sentence(ADOSDLY), dly_reas, sep = concat_sep), + !is.na(ADOSDLY) & ADOSDLY == "Y" & dly_reas == "" ~ paste( + stringr::str_to_sentence(ADOSDLY), + "", + sep = concat_sep + ), + !is.na(ADOSDLY) & dly_reas == "" ~ stringr::str_to_sentence(ADOSDLY), + TRUE ~ "" ), - # Optional Variable: AENTM COL8 = case_when( - AENDT == "" ~ "", - AENDT != "" & AENTM != "" & AENDY != "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), - AENDT != "" & AENTM == "" & AENDY != "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), - AENDT != "" & AENTM != "" & AENDY == "" ~ - paste0(AENDT, concat_sep, AENTM, " (-)"), - AENDT != "" & AENTM == "" & AENDY == "" ~ - paste0(AENDT, concat_sep, "--:--", " (-)"), + !is.na(AACTDU) & dreas != "" ~ paste(stringr::str_to_sentence(AACTDU), dreas, sep = concat_sep), + !is.na(AACTDU) & dreas == "" ~ paste(stringr::str_to_sentence(AACTDU), "", sep = concat_sep), + TRUE ~ "" ), - # Optional Column: COL9/AREASOC/AREASOO - COL9 = case_when( - toupper(AREASOC) == "OTHER" ~ - paste( - stringr::str_to_sentence(AREASOC), - stringr::str_to_sentence(AREASOO), - sep = ": " - ), - !is.na(AREASOC) ~ stringr::str_to_sentence(AREASOC), - is.na(AREASOC) ~ "" + COL9 = paste( + stringr::str_to_sentence(ACTDOSE), + ADOSFRQ, + sep = concat_sep ), - # Optional Column: COL10/AADJ/AADJOTH COL10 = case_when( - toupper(AADJ) == "OTHER" ~ - paste( - stringr::str_to_sentence(AADJ), - stringr::str_to_sentence(AADJOTH), - sep = ": " - ), - !is.na(AADJ) ~ stringr::str_to_sentence(AADJ), - is.na(AADJ) ~ "" + ASTDT == "" ~ "", + ASTDT != "" & ASTTM != "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + ASTDT != "" & ASTTM == "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + ASTDT != "" & ASTTM != "" & ASTDY == "" ~ paste0(ASTDT, concat_sep, ASTTM, " (-)"), + ASTDT != "" & ASTTM == "" & ASTDY == "" ~ paste0(ASTDT, concat_sep, "--:--", " (-)"), + ), + # Optional column: COL11/AENDT/AENDY + COL11 = case_when( + AENDT == "" ~ "", + AENDT != "" & AENDY != "" ~ paste0(AENDT, concat_sep, " (", AENDY, ")"), + AENDT != "" & AENDY == "" ~ paste0(AENDT, concat_sep, " (-)"), ) - ) %>% + ) |> arrange(COL0, COL1, COL2, !is.na(ASTDYN), ASTDYN, ASTDTM, AVISITN) lsting <- var_relabel( @@ -149,21 +182,20 @@ lsting <- var_relabel( COL0 = "Treatment Group", COL1 = "Subject ID", COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), - # Optional Column: COL3/AVISIT - COL3 = "Visit", - # Optional Column: COL4/ASCHDOSE/ASCHDOSU - COL4 = "Prescribed Dose Level (unit)", - COL5 = "Dose (unit)", - # Optional Column: COL6/ADOSFRM/ADOSFRQ/AROUTE - COL6 = paste("Formulation", "Frequency", "Route", sep = concat_sep), - # Optional Variable: ASTTM - COL7 = paste("Start Date", "Time (Study Day~[super a])", sep = concat_sep), - # Optional Variable: AENTM - COL8 = paste("End Date", "Time (Study Day~[super a])", sep = concat_sep), - # Optional Column: COL9/AREASOC/AREASOO - COL9 = "Reason Dose Not Administered, if Applicable", - # Optional Column: COL10/AADJ/AADJOTH - COL10 = "Reason Dose Adjusted, if Applicable" + # Optional Column: COL3/ATPT + COL3 = "Time Point", + COL4 = paste("Prescribed Dose (unit)", "Frequency", sep = concat_sep), + # Optional Column: COL5/ADOSFRM/AROUTE + COL5 = paste("Formulation", "Route", sep = concat_sep), + # Optional Column: COL6/AACTPR/AADJP/AADJPOTH/AEDECODy(if Adverse Event) + COL6 = paste("Action Taken to Prescribed Dose~[super a]", "Reason", sep = concat_sep), + # Optional column: COL7/ADOSDLY/ARSDOSD/ARSDSDO (Add when it is collected on study) + COL7 = paste("Dose Delayed?", "Reason", sep = concat_sep), + COL8 = paste("Action Taken With Study Treatment", "Reason", sep = concat_sep), + COL9 = paste("Actual Dose (unit)", "Frequency", sep = concat_sep), + COL10 = paste("Start Date", "Time (Study Day~[super a])", sep = concat_sep), + # Optional column: COL11/AENDT/AENDY + COL11 = paste("End Date", "(Study Day~[super a])", sep = concat_sep) ) ############################################################################### @@ -173,7 +205,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + sort_cols = sort_cols, + disp_cols = disp_cols, + round_type = "sas" ) ############################################################################### @@ -186,6 +220,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 18, 21, 19, 10, 73, 25, 25, 28, 21) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 18, 15, 21, 23, 39, 32, 33, 20, 25, 25) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsiex02.R b/tests/testthat/source_code/lsiex02.R index 8eee795f..e053bb36 100644 --- a/tests/testthat/source_code/lsiex02.R +++ b/tests/testthat/source_code/lsiex02.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsiex02.R -## R version: 4.2.1 -## Short Description: Create LSIEX02: Listing of Study Treatment -## Batch Lot Number -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-18 -## Input: ADEX -## Output: lsiex02.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -41,6 +15,7 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1") +sort_cols <- c("COL0", "COL1") disp_cols <- paste0("COL", 0:6) tab_titles <- list( title = "Dummy Title", @@ -53,10 +28,16 @@ tab_titles <- list( # Process data ############################################################################### -adex <- adex_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & ADOSE > 0) +adex <- adex_jnj |> + filter(!!rlang::sym(popfl) == "Y" & ADOSE > 0) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) -lsting <- adex %>% +lsting <- adex |> mutate( DAEXPDT = as.Date(DAEXPDTC, format = "%Y-%m-%d"), DAEXPYR = ifelse( @@ -79,7 +60,7 @@ lsting <- adex %>% substr(sub("T.*", "", DAEXPDTC), 9, 10), NA ), - ) %>% + ) |> unite( "DAEXPDTL", DAEXPDAY, @@ -88,19 +69,20 @@ lsting <- adex %>% sep = "", na.rm = TRUE, remove = FALSE - ) %>% + ) |> mutate( COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), # Optional Column: COL2/AVISIT - COL2 = explicit_na(AVISIT, ""), + COL2 = explicit_na(stringr::str_to_sentence(AVISIT), ""), # Optional Column: COL3/ASTDT COL3 = ifelse(!is.na(ASTDT), paste0(toupper(format(ASTDT, "%d%b%Y"))), ""), # Optional Column: COL4/ASTDTM COL4 = ifelse(!is.na(ASTDTM), substr(ASTDTM, 12, 16), ""), COL5 = explicit_na(EXLOT, ""), + # Optional Column: COL6/DAEXPDTC COL6 = explicit_na(DAEXPDTL, "") - ) %>% + ) |> arrange( COL0, COL1, @@ -127,6 +109,7 @@ lsting <- var_relabel( # COL4 = "Time Dispensed", COL4 = "Time Administered", COL5 = "Batch Lot Number", + # Optional Column: COL6/DAEXPDTC COL6 = "Batch Lot Expiration Date" ) @@ -137,7 +120,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + sort_cols = sort_cols, + disp_cols = disp_cols, + round_type = "sas" ) ############################################################################### @@ -150,6 +135,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(46, 63, 21, 23, 23, 65, 23) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(71, 63, 17, 23, 23, 65, 23) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/lsiex03.R b/tests/testthat/source_code/lsiex03.R index 7549d9e8..49cabb25 100644 --- a/tests/testthat/source_code/lsiex03.R +++ b/tests/testthat/source_code/lsiex03.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsiex03.R -## R version: 4.2.1 -## Short Description: Create LSIEX03: Listing of Study Treatment -## Administration for Infusions -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-01-19 -## Input: ADEX -## Output: lsiex03.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -41,7 +15,8 @@ fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2") -disp_cols <- paste0("COL", 0:11) +sort_cols <- c("COL0", "COL1", "COL2") +disp_cols <- paste0("COL", 0:15) concat_sep <- " / " tab_titles <- list( title = "Dummy Title", @@ -54,33 +29,73 @@ tab_titles <- list( # Process data ############################################################################### -adex <- adex_jnj %>% - filter(!!rlang::sym(popfl) == "Y") +adex <- adex_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + AVISIT = factor( + .data[["AVISIT"]], + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) + -lsting <- adex %>% +lsting <- adex |> mutate( - AACTDU1 = stringr::str_to_sentence(AACTDU1), - AACTDU2 = stringr::str_to_sentence(AACTDU2), - AACTDU3 = stringr::str_to_sentence(AACTDU3), - AACTDU4 = stringr::str_to_sentence(AACTDU4), - AACTDU5 = stringr::str_to_sentence(AACTDU5) - ) %>% + across(matches("^AACTDU\\d+$"), stringr::str_to_sentence), + across(matches("^ADECOD\\d+$"), stringr::str_to_sentence) + ) |> unite( "dact", - AACTDU1, - AACTDU2, - AACTDU3, - AACTDU4, - AACTDU5, + matches("^AACTDU\\d+$"), sep = ", ", na.rm = TRUE, remove = FALSE - ) %>% + ) |> + unite( + "decod", + matches("^ADECOD\\d+$"), + sep = ", ", + na.rm = TRUE, + remove = FALSE + ) |> mutate( dact = ifelse(dact == "", NA, dact), + decod = ifelse(decod == "", NA, decod), AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), ASTDT = ifelse( !is.na(ASTDT) & nchar(as.character(ASTDT)) == 10, toupper(format(ASTDT, "%d%b%Y")), @@ -98,72 +113,73 @@ lsting <- adex %>% AENDYN = ifelse(!is.na(AENDY), AENDY, NA), AENDY = ifelse(!is.na(AENDY), AENDY, ""), preas = case_when( - toupper(AADJP) == "ADVERSE EVENT" ~ stringr::str_to_sentence(AADJP), - toupper(AADJP) == "OTHER" ~ - paste0( - stringr::str_to_sentence(AADJP), - ": ", - stringr::str_to_sentence(AADJPOTH) - ), - is.na(AADJP) & !is.na(AACTPR) ~ "N/A" + toupper(AADJP) == "ADVERSE EVENT" ~ paste0(stringr::str_to_sentence(AADJP), " (AE: ", decod, ")"), + toupper(AADJP) == "OTHER" ~ paste0(stringr::str_to_sentence(AADJP), ": ", stringr::str_to_sentence(AADJPOTH)), + !is.na(AADJP) ~ stringr::str_to_sentence(AADJP), + TRUE ~ "" ), dreas = case_when( - toupper(AADJ) == "ADVERSE EVENT" ~ stringr::str_to_sentence(AADJ), - toupper(AADJ) == "OTHER" ~ - paste0( - stringr::str_to_sentence(AADJ), - ": ", - stringr::str_to_sentence(AADJOTH) - ), - is.na(AADJ) & !is.na(dact) ~ "N/A" + toupper(AADJ) == "ADVERSE EVENT" ~ paste0(stringr::str_to_sentence(AADJ), " (AE: ", decod, ")"), + toupper(AADJ) == "OTHER" ~ paste0(stringr::str_to_sentence(AADJ), ": ", stringr::str_to_sentence(AADJOTH)), + !is.na(AADJ) ~ stringr::str_to_sentence(AADJ), + TRUE ~ "" + ), + dly_reas = case_when( + !is.na(ARSDOSD) ~ stringr::str_to_sentence(ARSDOSD), + TRUE ~ "" ), COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), # Optional Column: COL3/AVISIT COL3 = explicit_na(AVISIT, ""), - # Optional Column: COL4/ASCHDOSE/ASCHDOSU COL4 = ifelse(is.na(ASCHDOSE), "", paste(ASCHDOSE, ASCHDOSU)), - COL5 = ifelse(is.na(ADOSE), "", paste(ADOSE, ADOSU)), - # Optional Column: COL6/ATVINF/ATVINFU - COL6 = ifelse(is.na(ATVINF), "", paste(ATVINF, ATVINFU)), - # Optional Column: COL7/AINFRAT/AINFRAU - COL7 = ifelse(is.na(AINFRAT), "", paste(AINFRAT, AINFRAU)), - COL8 = case_when( - ASTDT == "" ~ "", - ASTDT != "" & ASTTM != "" & ASTDY != "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), - ASTDT != "" & ASTTM == "" & ASTDY != "" ~ - paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), - ASTDT != "" & ASTTM != "" & ASTDY == "" ~ - paste0(ASTDT, concat_sep, ASTTM, " (-)"), - ASTDT != "" & ASTTM == "" & ASTDY == "" ~ - paste0(ASTDT, concat_sep, "--:--", " (-)"), - ), - COL9 = case_when( - AENDT == "" ~ "", - AENDT != "" & AENTM != "" & AENDY != "" ~ - paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), - AENDT != "" & AENTM == "" & AENDY != "" ~ - paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), - AENDT != "" & AENTM != "" & AENDY == "" ~ - paste0(AENDT, concat_sep, AENTM, " (-)"), - AENDT != "" & AENTM == "" & AENDY == "" ~ - paste0(AENDT, concat_sep, "--:--", " (-)"), + COL5 = case_when( + !is.na(AACTPR) & preas != "" ~ paste(stringr::str_to_sentence(AACTPR), preas, sep = concat_sep), + !is.na(AACTPR) & preas == "" ~ paste(stringr::str_to_sentence(AACTPR), "", sep = concat_sep), + TRUE ~ "" ), - # Optional Column: COL10/AACTPR/AADJP/AADJPOTH - COL10 = case_when( - !is.na(AACTPR) ~ paste(AACTPR_DECODE, preas, sep = concat_sep), - is.na(AACTPR) & !is.na(preas) ~ paste("", preas, sep = concat_sep), + # Optional Column: COL6/ADOSFRQP + COL6 = explicit_na(ADOSFRQP, ""), + # Optional Column: COL7/ADOSDLY/ARSDOSD + COL7 = case_when( + !is.na(ADOSDLY) & dly_reas != "" ~ paste(stringr::str_to_sentence(ADOSDLY), dly_reas, sep = concat_sep), + !is.na(ADOSDLY) & toupper(ADOSDLY) == "Y" & dly_reas == "" ~ paste( + stringr::str_to_sentence(ADOSDLY), + "", + sep = concat_sep + ), + !is.na(ADOSDLY) & dly_reas == "" ~ stringr::str_to_sentence(ADOSDLY), TRUE ~ "" ), - # Optional Column: COL11/AACTDU1-AACTDU5/AADJ/AADJOTH - COL11 = case_when( - !is.na(dact) ~ paste(dact, dreas, sep = concat_sep), - is.na(dact) & !is.na(dreas) ~ paste("", dreas, sep = concat_sep), + # Optional Column: COL8/ATDPRP/ATDPRPU + COL8 = ifelse(is.na(ATDPRP), "", paste(ATDPRP, ATDPRPU)), + COL9 = case_when( + !is.na(dact) & dreas != "" ~ paste(dact, dreas, sep = concat_sep), + !is.na(dact) & dreas == "" ~ paste(stringr::str_to_sentence(dact), "", sep = concat_sep), TRUE ~ "" - ) - ) %>% + ), + COL10 = ifelse(is.na(ACDOSE), "", ACDOSE), + # Optional Column: COL11/AINFRAT/AINFRAU + COL11 = ifelse(is.na(AINFRAT), "", paste(AINFRAT, AINFRAU)), + COL12 = ifelse(is.na(ADOSE), "", paste(ADOSE, ADOSU)), + COL13 = case_when( + ASTDT == "" ~ "", + ASTDT != "" & ASTTM != "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, ASTTM, " (", ASTDY, ")"), + ASTDT != "" & ASTTM == "" & ASTDY != "" ~ paste0(ASTDT, concat_sep, "--:--", " (", ASTDY, ")"), + ASTDT != "" & ASTTM != "" & ASTDY == "" ~ paste0(ASTDT, concat_sep, ASTTM, " (-)"), + ASTDT != "" & ASTTM == "" & ASTDY == "" ~ paste0(ASTDT, concat_sep, "--:--", " (-)"), + ), + COL14 = case_when( + AENDT == "" ~ "", + AENDT != "" & AENTM != "" & AENDY != "" ~ paste0(AENDT, concat_sep, AENTM, " (", AENDY, ")"), + AENDT != "" & AENTM == "" & AENDY != "" ~ paste0(AENDT, concat_sep, "--:--", " (", AENDY, ")"), + AENDT != "" & AENTM != "" & AENDY == "" ~ paste0(AENDT, concat_sep, AENTM, " (-)"), + AENDT != "" & AENTM == "" & AENDY == "" ~ paste0(AENDT, concat_sep, "--:--", " (-)"), + ), + # Optional Column: COL15/ADURC + COL15 = explicit_na(ADURC, "") + ) |> arrange( COL0, COL1, @@ -183,29 +199,43 @@ lsting <- var_relabel( COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), # Optional Column: COL3/AVISIT COL3 = "Visit", - # Optional Column: COL4/ASCHDOSE/ASCHDOSU COL4 = "Prescribed Dose Level (unit)", - COL5 = "Dose (unit)", - # Optional Column: COL6/ATVINF/ATVINFU - COL6 = "Total Volume Infused (unit)", - # Optional Column: COL7/AINFRAT/AINFRAU - COL7 = "Infusion Rate (unit)", - COL8 = paste("Start Date", "Time (Study Day~[super a])", sep = concat_sep), - COL9 = paste("End Date", "Time (Study Day~[super a])", sep = concat_sep), - # Optional Column: COL10/AACTPR/AADJP/AADJPOTH - COL10 = paste("Action Taken", "Reason Prior to Infusion", sep = concat_sep), - # Optional Column: COL11/AACTDU1-AACTDU5/AADJ/AADJOTH - COL11 = paste("Action Taken", "Reason During Infusion", sep = concat_sep) + COL5 = paste("Action Taken~[super a]", "Reason", sep = concat_sep), + # Optional Column: COL6/ADOSFRQP + COL6 = "Schedule Change New Dosing Frequency", + # Optional Column: COL7/ADOSDLY/ARSDOSD + COL7 = paste("Dose Delayed?", "Reason", sep = concat_sep), + # Optional Column: COL8/ATDPRP/ATDPRPU + COL8 = "Total Dose to be Administered (unit)", + COL9 = paste("Action Taken", "Reason", sep = concat_sep), + COL10 = "Total Volume of Investigational Product Infused (mL)", + # Optional Column: COL11/AINFRAT/AINFRAU + COL11 = "Infusion Rate (unit)", + COL12 = "Actual Dose Administered (unit)", + COL13 = paste("Start Date", "Time (Study Day~[super a])", sep = concat_sep), + COL14 = paste("End Date", "Time (Study Day~[super a])", sep = concat_sep), + # Optional Column: COL15/ADURC + COL15 = "Duration (hh:mm)" ) ############################################################################### # Build listing ############################################################################### +spanning_headers <- data.frame( + span_level = c(1L, 1L), + label = c("Prior to Infusion Start", "During Infusion"), + start = c(5L, 9L), + span = c(2L, 1L) +) + result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + sort_cols = sort_cols, + disp_cols = disp_cols, + spanning_col_labels = spanning_headers, + round_type = "sas" ) ############################################################################### @@ -218,6 +248,16 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 18, 21, 19, 10, 22, 15, 25, 25, 71, 25) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 17, 17, 18, 32, 18, 32, 23, 33, 25, 15, 23, 25, 25, 16) + +tt_to_tlgrtf( + result, + file = fileid, + orientation = "landscape", + border_fns = list( + tidytlg::no_borders, + tidytlg::spanning_borders(1), + tidytlg::row_border(2) + ) +) diff --git a/tests/testthat/source_code/lsiex04.R b/tests/testthat/source_code/lsiex04.R new file mode 100644 index 00000000..10d822a1 --- /dev/null +++ b/tests/testthat/source_code/lsiex04.R @@ -0,0 +1,249 @@ +library(envsetup) +library(tern) +library(dplyr) +library(tidyr) +library(rtables) +library(rlistings) +library(junco) + +############################################################################### +# Define script level parameters +############################################################################### + +tblid <- "LSIEX04" +fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +trtvar <- "TRT01A" +key_cols <- c("COL0", "COL1", "COL2") +sort_cols <- c("COL0", "COL1", "COL2") +disp_cols <- paste0("COL", 0:13) +concat_sep <- " / " +end_time <- TRUE +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +############################################################################### +# Process data +############################################################################### + +adex <- adex_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + case_when( + SEX == "M" ~ "Male", + SEX == "F" ~ "Female", + TRUE ~ SEX + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) |> + filter(!!rlang::sym(popfl) == "Y") + +lsting <- adex |> + mutate( + across(matches("^ADECOD\\d+$"), stringr::str_to_sentence) + ) |> + unite( + "decod", + matches("^ADECOD\\d+$"), + sep = ", ", + na.rm = TRUE, + remove = FALSE + ) |> + mutate( + decod = ifelse(decod == "", NA, decod), + AGE = explicit_na(as.character(AGE), ""), + SEX = explicit_na(SEX, ""), + RACE = explicit_na(RACE, ""), + ASCHDOSU = explicit_na(ASCHDOSU, ""), + AVAMTU = explicit_na(AVAMTU, ""), + ACDOSU = explicit_na(ACDOSU, ""), + ADOSU = explicit_na(ADOSU, ""), + ASTDT = ifelse( + !is.na(ASTDT) & nchar(as.character(ASTDT)) == 10, + toupper(format(ASTDT, "%d%b%Y")), + "" + ), + ASTDY = ifelse(!is.na(ASTDY), ASTDY, ""), + ASTDYL = ifelse(!is.na(ASTDT) & is.na(ASTDY), "-", as.character(ASTDY)), + ASTTM = ifelse(!is.na(ASTDTM), substr(as.character(ASTDTM), 12, 16), ""), + AENTM = if_else(end_time & !is.na(AENDTM), substr(as.character(AENDTM), 12, 16), ""), + preas = case_when( + toupper(AADJP) == "ADVERSE EVENT" ~ paste0(stringr::str_to_sentence(AADJP), " (AE: ", decod, ")"), + toupper(AADJP) == "OTHER" ~ + paste0( + stringr::str_to_sentence(AADJP), + ": ", + stringr::str_to_sentence(AADJPOTH) + ), + !is.na(AADJP) ~ stringr::str_to_sentence(AADJP), + TRUE ~ "" + ), + dreas = case_when( + toupper(AADJ) == "ADVERSE EVENT" ~ paste0(stringr::str_to_sentence(AADJ), " (AE: ", decod, ")"), + toupper(AADJ) == "OTHER" ~ + paste0( + stringr::str_to_sentence(AADJ), + ": ", + stringr::str_to_sentence(AADJOTH) + ), + !is.na(AADJ) ~ stringr::str_to_sentence(AADJ), + TRUE ~ "" + ), + dly_reas = case_when( + !is.na(ARSDOSD) ~ stringr::str_to_sentence(ARSDOSD), + TRUE ~ "" + ), + COL0 = explicit_na(.data[[trtvar]], ""), + COL1 = explicit_na(USUBJID, ""), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), + # Optional Column: COL3/AVISIT + COL3 = explicit_na(stringr::str_to_sentence(AVISIT), ""), + # Prescribed: COL4/ASCHDOSE/ASCHDOSU + COL4 = ifelse(is.na(ASCHDOSE), "", paste(ASCHDOSE, ASCHDOSU)), + # Prescribed: COL5/ADOSE/ADOSU (Injection Volume) + COL5 = ifelse(is.na(AVAMT), "", AVAMT), + # Prior to Injection Start: COL6/AACTPR/AADJP/AADJPOTH (Action Taken / Reason) + COL6 = case_when( + !is.na(AACTPR) ~ paste(stringr::str_to_sentence(AACTPR), preas, sep = concat_sep), + !is.na(AACTPR) & is.na(preas) ~ paste(stringr::str_to_sentence(AACTPR), "", sep = concat_sep), + TRUE ~ "" + ), + # Optional column Prior to Injection Start: COL7/Schedule Change New Dosing Frequency + COL7 = explicit_na(ADOSFRQP, ""), + # Optional Prior to Injection Start: COL8/Dose Delayed? / Reason + COL8 = case_when( + !is.na(ADOSDLY) & dly_reas != "" ~ paste(stringr::str_to_sentence(ADOSDLY), dly_reas, sep = concat_sep), + !is.na(ADOSDLY) & dly_reas == "" ~ paste(stringr::str_to_sentence(ADOSDLY)), + TRUE ~ "" + ), + # During Injection: COL9/AACTDU1-AACTDU5/AADJ/AADJOTH (Action Taken / Reason) + COL9 = case_when( + !is.na(AACTDU) & dreas != "" ~ paste(stringr::str_to_sentence(AACTDU), dreas, sep = concat_sep), + !is.na(AACTDU) & dreas == "" ~ paste(stringr::str_to_sentence(AACTDU), "", sep = concat_sep), + TRUE ~ "" + ), + COL10 = ifelse(is.na(ACDOSE), "", ACDOSE), + COL11 = ifelse(is.na(ADOSE), "", paste(ADOSE, ADOSU)), + # Start Date (Study Day) + COL12 = case_when( + !is.na(ASTDT) & !is.na(ASTDYL) ~ paste0(toupper(ASTDT), " (", ASTDYL, ")"), + !is.na(ASTDT) & is.na(ASTDYL) ~ toupper(ASTDT), + TRUE ~ "" + ), + COL13 = case_when( + !end_time & ASTTM != "" ~ ASTTM, + !end_time ~ "", + ASTTM == "" & AENTM == "" ~ "", + ASTTM != "" & AENTM != "" ~ paste0(ASTTM, concat_sep, AENTM), + ASTTM != "" & AENTM == "" ~ paste0(ASTTM, concat_sep, "--:--"), + ASTTM == "" & AENTM != "" ~ paste0("--:--", concat_sep, AENTM), + TRUE ~ "" + ) + ) |> + arrange( + COL0, + COL1, + COL2 + ) + +lsting <- var_relabel( + lsting, + COL0 = "Treatment Group", + COL1 = "Subject ID", + COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), + # Optional Column: COL3/AVISIT + COL3 = "Visit", + COL4 = "Dose [Level] (unit)", + COL5 = "Injection Volume (mL)", + COL6 = paste("Action Taken~[super a]", "Reason", sep = concat_sep), + # Optional Prior to Injection Start: Schedule Change New Dosing Frequency + COL7 = "Schedule Change New Dosing Frequency", + # Optional Prior to Injection Start: Dose Delayed? / Reason + COL8 = paste("Dose Delayed?", "Reason", sep = concat_sep), + COL9 = paste("Action Taken", "Reason", sep = concat_sep), + COL10 = "Volume of Investigation Product Injected (mL)", + COL11 = "Actual Dose Administered (unit)", + COL12 = "Start Date (Study Day~[super b])", + COL13 = if (end_time) paste("Start Time", "End Time", sep = concat_sep) else "Start Time" +) + +############################################################################### +# Build listing +############################################################################### + +spanning_labels <- data.frame( + span_level = 1L, + label = c("Prescribed", "Prior to Injection Start", "During Injection"), + start = c(5L, 7L, 10L), + span = c(2L, 2L, 1L) +) + +result <- rlistings::as_listing( + df = lsting, + key_cols = key_cols, + disp_cols = disp_cols, + spanning_col_labels = spanning_labels, + sort_cols = sort_cols, + round_type = "sas" +) + +############################################################################### +# Add titles and footnotes +############################################################################### + +result <- set_titles(result, tab_titles) + +############################################################################### +# Output listing +############################################################################### + + +colwidth <- c(21, 13, 17, 17, 18, 18, 32, 18, 32, 33, 22, 23, 23, 13) + +tt_to_tlgrtf( + result, + file = fileid, + orientation = "landscape", + border_fns = list( + tidytlg::no_borders, + tidytlg::spanning_borders(1), + tidytlg::row_border(2) + ) +) diff --git a/tests/testthat/source_code/lsimh01.R b/tests/testthat/source_code/lsimh01.R index e2630b76..4addbc4f 100644 --- a/tests/testthat/source_code/lsimh01.R +++ b/tests/testthat/source_code/lsimh01.R @@ -1,29 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: lsimh01.R -## R version: 4.2.1 -## Short Description: Create LSIMH01: Listing of [Medical -## History/Medical History of Interest] -## Author: Johnson & Johnson Innovative Medicine -## Date: 2024-02-09 -## Input: ADSL, MH -## Output: lsimh01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -39,8 +13,9 @@ library(junco) tblid <- "LSIMH01" fileid <- write_path(opath, tblid) popfl <- "FASFL" -trtvar <- "TRT01P" +trtvar <- "TRT01A" key_cols <- c("COL0", "COL1", "COL2") +sort_cols <- c("COL0", "COL1", "COL2", "MHSTDTC", "MHBODSYS", "MHDECOD") disp_cols <- paste0("COL", 0:8) concat_sep <- " / " tab_titles <- list( @@ -54,30 +29,78 @@ tab_titles <- list( # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") - -mh <- mh_jnj - -adsl_mh <- adsl %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male" + ), + levels = c("Male", "Female") + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ) + ) + +mh <- mh_jnj |> + # user can filter appropriate value of MHCAT for medical histrory of intreset and MHOCCUR + filter(stringr::str_to_upper(MHCAT) == "GENERAL MEDICAL HISTORY") + + +adsl_mh <- adsl |> inner_join(mh, by = c("STUDYID", "USUBJID")) -lsting <- adsl_mh %>% +lsting <- adsl_mh |> mutate( AGE = explicit_na(as.character(AGE), ""), SEX = explicit_na(SEX, ""), - RACE_DECODE = explicit_na(RACE_DECODE, ""), + RACE = explicit_na(RACE, ""), MHDECOD = case_when( - MHDECOD == "" ~ paste0("Uncoded: ", MHTERM), + MHDECOD == "" | is.na(MHDECOD) ~ paste0("Uncoded: ", MHTERM), .default = MHDECOD ), MHBODSYS = case_when( - MHBODSYS == "" ~ "Uncoded", + MHBODSYS == "" | is.na(MHBODSYS) ~ "Uncoded", .default = MHBODSYS ), MHDECOD = explicit_na(MHDECOD, ""), MHTERM = explicit_na(MHTERM, ""), - MHENRTPTL = ifelse(MHENRTPT == "ONGOING", "Yes", "No"), + MHENRTPTL = case_when( + MHENRTPT == "ONGOING" ~ "Yes", + MHENRTPT == "BEFORE" ~ "No", + TRUE ~ NA_character_ + ), MHSTDT = as.Date(MHSTDTC, format = "%Y-%m-%d"), MHSTYR = ifelse( stringr::str_length(MHSTDTC) >= 4, @@ -124,7 +147,7 @@ lsting <- adsl_mh %>% is.na(MHENDY) & !is.na(MHENDT) ~ "-", TRUE ~ NA ), - ) %>% + ) |> unite( "MHSTDTL", MHSTDAY, @@ -133,7 +156,7 @@ lsting <- adsl_mh %>% sep = "", na.rm = TRUE, remove = FALSE - ) %>% + ) |> unite( "MHENDTL", MHENDAY, @@ -142,31 +165,27 @@ lsting <- adsl_mh %>% sep = "", na.rm = TRUE, remove = FALSE - ) %>% + ) |> mutate( COL0 = explicit_na(.data[[trtvar]], ""), COL1 = explicit_na(USUBJID, ""), - COL2 = paste(AGE, SEX, RACE_DECODE, sep = concat_sep), - COL3 = explicit_na(MHBODSYS, ""), - COL4 = paste(MHDECOD, MHTERM, sep = concat_sep), + COL2 = paste(AGE, SEX, RACE, sep = concat_sep), + COL3 = stringr::str_to_sentence(explicit_na(MHBODSYS, "")), + COL4 = stringr::str_to_sentence(paste(MHDECOD, MHTERM, sep = concat_sep)), COL5 = case_when( - MHSTDTL != "" & !is.na(MHSTDYL) ~ - paste0(toupper(MHSTDTL), " (", MHSTDYL, ")"), - MHSTDTL != "" & is.na(MHSTDYL) ~ - paste0(toupper(MHSTDTL), ""), + (MHSTDTL != "" | !is.na(MHSTDTL)) & !is.na(MHSTDYL) ~ paste0(toupper(MHSTDTL), " (", MHSTDYL, ")"), + MHSTDTL != "" & is.na(MHSTDYL) ~ paste0(toupper(MHSTDTL), ""), TRUE ~ "" ), COL6 = case_when( - MHENDTL != "" & !is.na(MHENDYL) ~ - paste0(toupper(MHENDTL), " (", MHENDYL, ")"), - MHENDTL != "" & is.na(MHENDYL) ~ - paste0(toupper(MHENDTL), ""), + (MHENDTL != "" | !is.na(MHENDTL)) & !is.na(MHENDYL) ~ paste0(toupper(MHENDTL), " (", MHENDYL, ")"), + MHENDTL != "" & is.na(MHENDYL) ~ paste0(toupper(MHENDTL), ""), TRUE ~ "" ), COL7 = explicit_na(MHENRTPTL, ""), # Optional Column: COL8/MHTOXGR COL8 = explicit_na(MHTOXGR, ""), - ) %>% + ) |> arrange(COL0, COL1, COL2, MHSTDTC, MHBODSYS, MHDECOD) lsting <- var_relabel( @@ -175,7 +194,7 @@ lsting <- var_relabel( COL1 = "Subject ID", COL2 = paste("Age (years)", "Sex", "Race", sep = concat_sep), COL3 = "System Organ Class", - COL4 = paste("[Preferred Term", "Reported Term]", sep = concat_sep), + COL4 = paste("Preferred Term", "Reported Term", sep = concat_sep), COL5 = "Start Date (Study Day)~[super a]", COL6 = "End Date (Study Day)~[super a]", COL7 = "Ongoing?", @@ -190,7 +209,9 @@ lsting <- var_relabel( result <- rlistings::as_listing( df = lsting, key_cols = key_cols, - disp_cols = disp_cols + disp_cols = disp_cols, + sort_cols = sort_cols, + round_type = "sas" ) ############################################################################### @@ -203,6 +224,7 @@ result <- set_titles(result, tab_titles) # Output listing ############################################################################### -colwidth <- c(21, 13, 18, 91, 64, 23, 23, 17, 15) -tt_to_tlgrtf(colwidths = colwidth, head(result, 100), file = fileid, orientation = "landscape") +colwidth <- c(21, 13, 54, 78, 41, 23, 23, 17, 15) + +tt_to_tlgrtf(head(result, 100), file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/markedlyabnormal.xlsx b/tests/testthat/source_code/markedlyabnormal.xlsx index c4ace718..cb463260 100644 Binary files a/tests/testthat/source_code/markedlyabnormal.xlsx and b/tests/testthat/source_code/markedlyabnormal.xlsx differ diff --git a/tests/testthat/source_code/tcrae01.R b/tests/testthat/source_code/tcrae01.R new file mode 100644 index 00000000..63f3b684 --- /dev/null +++ b/tests/testthat/source_code/tcrae01.R @@ -0,0 +1,211 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +# - Define how to create combined treatment columns (if required) +################################################################################ + +tblid <- "TCRAE01" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +trtvar <- "TRT01A" +popfl <- "SAFFL" +subjFilterText <- "Subjects with >=1 non-serious AE" + +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +################################################################################ +# Process Data: +################################################################################ + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & AESER == "N") |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AESER) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +# join data together +ae <- adae |> right_join(adsl, by = c("USUBJID")) + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = "Placebo", + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +################################################################################ +# Define layout and build table: +################################################################################ + +extra_args_1 <- list( + denom = "n_altdf", + .stats = c("count_unique_fraction") +) + + +lyt <- rtables::basic_table( + top_level_section_div = " ", + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +lyt <- lyt |> + analyze( + "TRTEMFL", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_1, + list(label = subjFilterText, val = "Y") + ) + ) |> + split_rows_by( + "AEBODSYS", + child_labels = "hidden", + split_label = "System Organ Class", + label_pos = "topleft", + split_fun = trim_levels_in_group("AEDECOD"), + section_div = c(" "), + indent_mod = 0L + ) |> + summarize_row_groups( + "AEBODSYS", + cfun = a_freq_j, + extra_args = extra_args_1 + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) |> + append_topleft(" Preferred Term, n (%)") + +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") + +# If there is no data remove top row and display "No data to display" text +if (length(adae$TRTEMFL) == 0) { + result <- safe_prune_table( + result, + prune_func = remove_rows(removerowtext = subjFilterText) + ) +} + +######################################################################################### +# Post-Processing step to sort by descending count on chosen active treatment columns. +# Default is the last treatment (inc. Combined if applicable) under the active treatment +# spanning header (defaulted to colspan_trt variable). See function documentation for +# jj_complex_scorefun should your require a different sorting behavior. +######################################################################################### + +if (length(adae$TRTEMFL) != 0) { + result <- sort_at_path( + result, + c("root", "AEBODSYS"), + scorefun = jj_complex_scorefun() + ) + result <- sort_at_path( + result, + c("root", "AEBODSYS", "*", "AEDECOD"), + scorefun = jj_complex_scorefun() + ) + + ################################################################################ + # Prune table to only keep those that meet x% criteria, but top row is not subject to pruning + ################################################################################ + result <- safe_prune_table( + result, + prune_func = bspt_pruner( + fraction = 0.05, + keeprowtext = subjFilterText, + cols = c(trtvar) + ) + ) +} + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tirada01.R b/tests/testthat/source_code/tirada01.R new file mode 100644 index 00000000..2231f2ef --- /dev/null +++ b/tests/testthat/source_code/tirada01.R @@ -0,0 +1,435 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRADA01" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "IMFL" # Immunogenicity Analysis Set flag +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +parqual_value <- "XANOMELINE" +combined_colspan_trt <- TRUE +include_ctrl_grp <- FALSE # set to FALSE to exclude control group (e.g. Placebo) from the table +study_agent <- "active study agent" +agent_antibody_label <- sprintf("antibodies to %s", study_agent) + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + select( + USUBJID, + all_of(trtvar), + colspan_trt + ) + +adishum_raw <- adishum_jnj + +adishum <- adishum_raw |> + filter( + toupper(PARQUAL) == toupper(parqual_value) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + +# left join from adsl to include all eligible subjects +# colspan_trt and trtvar (with factor levels) come from adsl +adishum <- adsl |> + left_join( + adishum |> + select(-all_of(trtvar)), + by = "USUBJID" + ) + +# Section --- Auxilary Datasets Needed For Final Dataset ------------ + +# each has a flag PARAMCD and a titer PARAMCD +ada_sections <- list( + list(flag = "ADABL", flag_col = "adabl_flag", titer = "ADABLT", titer_col = "adablt_titer"), + list(flag = "ADATRB", flag_col = "adatrb_flag", titer = "ADATRBT", titer_col = "adatrbt_titer"), + list(flag = "ADANTRB", flag_col = "adantrb_flag", titer = "ADANTRBT", titer_col = "adantrbt_titer"), + list(flag = "ADATRI", flag_col = "adatri_flag", titer = "ADATRIPT", titer_col = "adatript_titer"), + list(flag = "ADATRE", flag_col = "adatre_flag", titer = "ADATREPT", titer_col = "adatrept_titer"), + list(flag = "ADANTRE", flag_col = "adantre_flag", titer = NULL, titer_col = NULL) +) + +# join all flag and titer columns onto one subject-level dataset +for (section in ada_sections) { + flag_df <- adishum |> + filter(PARAMCD == section$flag) |> + select(USUBJID, !!section$flag_col := AVALC) + + adishum <- adishum |> + left_join(flag_df, by = "USUBJID") + + if (!is.null(section$titer)) { + titer_df <- adishum |> + filter(PARAMCD == section$titer) |> + select(USUBJID, !!section$titer_col := AVALC) + + adishum <- adishum |> + left_join(titer_df, by = "USUBJID") + } +} + +# convert all titer values in an ordered factor +adishum <- adishum |> + mutate( + across( + ends_with("_flag"), + ~ dplyr::if_else(is.na(.), "N", as.character(.)) + ), + across( + ends_with("_titer"), + ~ { + vals <- unique(.[!is.na(.)]) + vals_matched <- vals[grepl(":(\\d+)", vals)] + nums <- vals_matched |> + sub( + pattern = ".*:(\\d+).*", + replacement = "\\1" + ) |> + as.numeric() + ordered_levels <- vals_matched[order(nums)] + factor(., levels = ordered_levels) + } + ) + ) + +# peak titer group from AVALCAT1 (not AVALC) +adatrept_cat_df <- adishum |> + filter(PARAMCD == "ADATREPT") |> + select(USUBJID, adatrept_cat = AVALCAT1) + +adishum <- adishum |> + left_join(adatrept_cat_df, by = "USUBJID") |> + mutate( + adatrept_cat = case_when( + adatre_flag == "Y" & !is.na(adatrept_cat) ~ as.character(adatrept_cat), + adatre_flag == "Y" & is.na(adatrept_cat) ~ "No titer", + TRUE ~ NA_character_ + ), + adatrept_cat = factor( + adatrept_cat, + levels = c("<10", "10 to <100", "100 to <1000", ">=1000", "No titer") + ) + ) + +# programming note 3: check if any subjects positive per section +has_adabl <- any(adishum$adabl_flag == "Y", na.rm = TRUE) +has_adatrb <- any(adishum$adatrb_flag == "Y", na.rm = TRUE) +has_adantrb <- any(adishum$adantrb_flag == "Y", na.rm = TRUE) +has_adatri <- any(adishum$adatri_flag == "Y", na.rm = TRUE) +has_adatre <- any(adishum$adatre_flag == "Y", na.rm = TRUE) + +# final output needs only these columns +adishum <- adishum |> + select( + USUBJID, + all_of(trtvar), # TRT01A + colspan_trt, # column split + # flag columns + adabl_flag, + adatrb_flag, + adantrb_flag, + adatri_flag, + adatre_flag, + adantre_flag, + # titer columns + adablt_titer, + adatrbt_titer, + adantrbt_titer, + adatript_titer, + adatrept_titer, + # peak titer group + adatrept_cat + ) |> + unique() + +# Section --- Prepare Rtables Helpers ------------ +# add the Combined column via split function +if (combined_colspan_trt) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline Low Dose", "Xanomeline High Dose") # UPDATE + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +# colspan map built from adsl, not adishum +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar +) + +if (!include_ctrl_grp) { + colspan_trt_map <- colspan_trt_map |> + filter(.data[[trtvar]] != ctrl_grp) +} + +################################################################################ +# Define layout and build table: +################################################################################ +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + append_topleft( + c("Antibody Status", indent_string("Titer", 1L)) + ) |> + # define column splits + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) |> + split_cols_by(trtvar, split_fun = mysplit) |> + # define analysis variable + # Section 1: baseline positive flag row + analyze( + "adabl_flag", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects positive for %s at baseline~[super a], n (%%)", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique_fraction") + ) + ) + +# programming note 3: titer rows only if positives exist +if (has_adabl) { + lyt <- lyt |> + analyze( + "adablt_titer", + afun = a_freq_j, + show_labels = "visible", + var_labels = "Baseline titers", + indent_mod = 1L, + section_div = " ", + extra_args = list(.stats = c("count_unique")) + ) +} + +lyt <- lyt |> + # Section 2: treatment-boosted flag row + analyze( + "adatrb_flag", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects positive for %s at baseline who were treatment-boosted for %s~[super b], n (%%)", + agent_antibody_label, + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique_fraction") + ) + ) + +if (has_adatrb) { + lyt <- lyt |> + analyze( + "adatrbt_titer", + afun = a_freq_j, + show_labels = "visible", + var_labels = "Baseline titers", + indent_mod = 1L, + section_div = " ", + extra_args = list(.stats = c("count_unique")) + ) +} + +lyt <- lyt |> + # Section 3: not treatment-boosted flag row + analyze( + "adantrb_flag", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects positive for %s at baseline who were not treatment-boosted for %s~[super c], n (%%)", + agent_antibody_label, + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique_fraction") + ) + ) + +if (has_adantrb) { + lyt <- lyt |> + analyze( + "adantrbt_titer", + afun = a_freq_j, + show_labels = "visible", + var_labels = "Baseline titers", + section_div = " ", + indent_mod = 1L, + extra_args = list(.stats = c("count_unique")) + ) +} + +lyt <- lyt |> + # Section 4: treatment-induced flag row + analyze( + "adatri_flag", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects positive for treatment-induced %s~[super d], n (%%)", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique_fraction") + ) + ) + +if (has_adatri) { + lyt <- lyt |> + analyze( + "adatript_titer", + afun = a_freq_j, + show_labels = "visible", + var_labels = "Peak titers", + section_div = " ", + indent_mod = 1L, + extra_args = list(.stats = c("count_unique")) + ) +} + +lyt <- lyt |> + # Section 5: treatment-emergent flag row + analyze( + "adatre_flag", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects positive for treatment-emergent %s~[super e], n (%%)", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique_fraction") + ) + ) + +if (has_adatre) { + lyt <- lyt |> + analyze( + "adatrept_titer", + afun = a_freq_j, + show_labels = "visible", + var_labels = "Peak titers", + section_div = " ", + indent_mod = 1L, + extra_args = list(.stats = c("count_unique")) + ) +} + +lyt <- lyt |> + # Section 6: peak titer group — always shown + analyze( + "adatrept_cat", + afun = a_freq_j, + show_labels = "visible", + var_labels = "Peak titer group~[super f]", + section_div = " ", + indent_mod = 1L, + extra_args = list( + .stats = c("count_unique_fraction"), + denom = "n_df", + excl_levels = "No titer" + ) + ) |> + # Section 7: negative for treatment-emergent flag row + analyze( + "adantre_flag", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects negative for treatment-emergent %s~[super g], n (%%)", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique_fraction") + ) + ) + +# Section --- Create Table Shell ------------ + +result <- build_table(lyt, adishum, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 23, 23, 25) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirada02.R b/tests/testthat/source_code/tirada02.R new file mode 100644 index 00000000..48de001e --- /dev/null +++ b/tests/testthat/source_code/tirada02.R @@ -0,0 +1,535 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRADA02" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "SAFFL" # Safety Analysis Set flag +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +parqual_value <- "XANOMELINE" +ae_filter_exp <- expr(toupper(AESCAT) == toupper("infusion related reaction")) # user sets this to match ADAE.AESCAT +sev_grade_fl <- "AESEV" +# sev_grade_fl <- "AETOXGRN" +sev_grade_lbl <- "severe" +# sev_grade_lbl <- ">=grade 3" +adexsum_tnumd_paramcd <- "TNUMDOS" # set to TNUMDSSx as needed +dosedt_var <- "DOSEDT" # set to DOSSxDT as needed +combined_colspan_trt <- TRUE +include_ctrl_grp <- FALSE # set to FALSE to exclude control group (e.g. Placebo) from the table +study_agent <- "active study agent" +agent_antibody_label <- sprintf("antibodies to %s", study_agent) + +################################################################################ +# Process data: +################################################################################ + +# create filter for severity +sev_filter_exp <- if (sev_grade_fl == "AESEV") { + expr(toupper(!!sym(sev_grade_fl)) == toupper(sev_grade_lbl)) +} else { + expr(!!sym(sev_grade_fl) >= 3) +} + +# Read all raw datasets once; apply only population/key filters here +adsl_raw <- adsl_jnj |> + filter(.data[[popfl]] == "Y") + +adishum_raw <- adishum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARQUAL) == toupper(parqual_value) + ) + +adae_raw <- adae_jnj |> + filter( + .data[[popfl]] == "Y", + !!ae_filter_exp + ) + +adexsum_raw <- adexsum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARAMCD) == toupper(adexsum_tnumd_paramcd) + ) |> + select(USUBJID, INFUSAN = AVAL) + +# ADSL: Derive analysis-ready adsl with colspan variable +adsl <- adsl_raw |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + select( + USUBJID, + all_of(trtvar), + colspan_trt + ) + +# ADISHUM: one row per subject; derive antibody status flags and carry IMEVFL +adishum <- adishum_raw |> + select(USUBJID, ADATRES, IMEVFL) |> + filter(!is.na(ADATRES)) |> + distinct(USUBJID, .keep_all = TRUE) |> + mutate( + adatre_flg = if_else(toupper(ADATRES) == "POSITIVE", "Y", "N"), + adantre_flg = if_else(toupper(ADATRES) == "NEGATIVE", "Y", "N") + ) |> + select(USUBJID, adatre_flg, adantre_flg, IMEVFL) + +# ADAE: subject-level flags (distinct USUBJID per flag) +# NOTE: always count distinct subjects after subsetting on AESCAT + ADATRES + applicable attribute +adae_irr <- adae_raw |> + distinct(USUBJID) |> + mutate(infureact_flg = "Y") # any infusion-related reaction + +# Purpose: flag subjects meeting severity/grade threshold per sev_filter_exp +adae_sev <- adae_raw |> + filter(!!sev_filter_exp) |> + distinct(USUBJID) |> + mutate(sev_flg = "Y") + +adae_ser <- adae_raw |> + filter(toupper(AESER) == "Y") |> + distinct(USUBJID) |> + mutate(ser_flg = "Y") # AESER=Y + +adae_treat_discon <- adae_raw |> + filter(toupper(TRDISCFL) == "Y") |> + distinct(USUBJID) |> + mutate(treat_discon_flg = "Y") # TRDISCFL=Y + +adae_dosct <- adexsum_raw |> + select(USUBJID) |> + left_join( + adae_raw |> + group_by(USUBJID) |> + summarise( + n_dosedt_num = n_distinct(.data[[dosedt_var]], na.rm = TRUE), + .groups = "drop" + ), + by = "USUBJID" + ) |> + mutate(n_dosedt_num = if_else(is.na(n_dosedt_num), 0, n_dosedt_num)) + +# Final join: adsl -> adishum -> imevfl -> all adae flags -> adexsum +# Each auxiliary dataset has one row per subject — no many-to-many +join_list <- list( + adae_irr, + adae_sev, + adae_ser, + adae_treat_discon, + adae_dosct, + adexsum_raw +) + +adishum <- adsl |> + left_join(adishum, by = "USUBJID") |> + purrr::reduce(join_list, ~ left_join(.x, .y, by = "USUBJID"), .init = _) |> + distinct(USUBJID, .keep_all = TRUE) |> + mutate( + across( + c(infureact_flg, sev_flg, ser_flg, treat_discon_flg), + ~ if_else(is.na(.), "N", as.character(.)) + ) + ) + +# Section --- Build analysis flags from joined columns ------------ +# Section 1 --- Adatre Positive (Treatment-Emergent Antibody Positive) ------------ +adishum <- adishum |> + mutate( + # infureact_pos_flg: any infusion-related reaction in adae (AESCAT filter already applied) + infureact_pos_flg = case_when( + adatre_flg == "Y" & infureact_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # sev_pos_flg: per sev_filter_exp + sev_pos_flg = case_when( + adatre_flg == "Y" & sev_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # ser_pos_flg: AESER=Y + ser_pos_flg = case_when( + adatre_flg == "Y" & ser_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # treat_discon_pos_flg: TRDISCFL=Y + treat_discon_pos_flg = case_when( + adatre_flg == "Y" & treat_discon_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # infusan_pos_flg: total infusions from ADEXSUM for positive subjects (denominator for footnote e) + infusan_pos_flg = if_else(adatre_flg == "Y", INFUSAN, NA_real_), + # infusarn_pos_flg: distinct IRR infusion dates for positive subjects (numerator for footnote e) + infusarn_pos_flg = if_else(adatre_flg == "Y", as.numeric(n_dosedt_num), NA_real_) + ) + +# Section 2 --- Adantre Negative (Treatment-Emergent Antibody Negative) ------------ +adishum <- adishum |> + mutate( + # infureact_neg_flg: any infusion-related reaction in adae + infureact_neg_flg = case_when( + adantre_flg == "Y" & infureact_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # sev_neg_flg: per sev_filter_exp + sev_neg_flg = case_when( + adantre_flg == "Y" & sev_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # ser_neg_flg: AESER=Y + ser_neg_flg = case_when( + adantre_flg == "Y" & ser_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # treat_discon_neg_flg: TRDISCFL=Y + treat_discon_neg_flg = case_when( + adantre_flg == "Y" & treat_discon_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # infusan_neg_flg: total infusions from ADEXSUM for negative subjects (denominator for footnote e) + infusan_neg_flg = if_else( + adantre_flg == "Y", + INFUSAN, + NA_real_ + ), + # infusarn_neg_flg: distinct IRR infusion dates for negative subjects (numerator for footnote e) + infusarn_neg_flg = if_else( + adantre_flg == "Y", + as.numeric(n_dosedt_num), + NA_real_ + ) + ) + +# final output needs only these columns +adishum <- adishum |> + select( + USUBJID, + all_of(trtvar), + colspan_trt, + IMEVFL, + adatre_flg, + adantre_flg, + infureact_pos_flg, + sev_pos_flg, + ser_pos_flg, + treat_discon_pos_flg, + infusan_pos_flg, + infusarn_pos_flg, + infureact_neg_flg, + sev_neg_flg, + ser_neg_flg, + treat_discon_neg_flg, + infusan_neg_flg, + infusarn_neg_flg + ) |> + unique() + +# Section --- Prepare Rtables Helpers ------------ +# add the Combined column via split function +if (combined_colspan_trt) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline Low Dose", "Xanomeline High Dose") # UPDATE + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +# colspan map built from adsl, not adishum +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar +) + +if (!include_ctrl_grp) { + colspan_trt_map <- colspan_trt_map |> + filter(.data[[trtvar]] != ctrl_grp) +} + +################################################################################ +# Define layout and build table: +################################################################################ +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map( + map = colspan_trt_map + ) + ) |> + split_cols_by( + trtvar, + split_fun = mysplit + ) |> + analyze( + "IMEVFL", + afun = a_freq_j, + show_labels = "hidden", + section_div = " ", + extra_args = list( + label = "Subjects with evaluable samples~[super a]", + val = "Y", + .stats = c("count_unique") + ) + ) |> + # Section 1 --- Adatre Positive (Treatment-Emergent Antibody Positive) ------------ + analyze( + "adatre_flg", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects positive for treatment-emergent %s~[super b,d]", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "infureact_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion-related reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "sev_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = sprintf( + "Subjects with %s infusion-related reaction, n (%%)", + sev_grade_lbl + ), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "ser_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with serious infusion-related reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "treat_discon_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion-related reaction leading to treatment discontinuation, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "infusan_pos_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + .stats = "sum_unique", + .labels = c( + sum_unique = sprintf( + "Total number of %s infusions", + study_agent + ) + ), + id_var = "USUBJID" + ) + ) |> + analyze( + "infusarn_pos_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 2L, + section_div = " ", + extra_args = list( + .stats = "ratio_unique", + .labels = c( + ratio_unique = "Infusions with infusion-related reactions~[super e], n (%)" + ), + denom_by = "infusan_pos_flg", + id_var = "USUBJID" + ) + ) |> + # Section 2 --- Adantre Negative (Treatment-Emergent Antibody Negative) ------------ + analyze( + "adantre_flg", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects negative for treatment-emergent %s~[super c,d]", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "infureact_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion-related reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "sev_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = sprintf( + "Subjects with %s infusion-related reaction, n (%%)", + sev_grade_lbl + ), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "ser_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with serious infusion-related reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "treat_discon_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion-related reaction leading to treatment discontinuation, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "infusan_neg_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + .stats = "sum_unique", + .labels = c( + sum_unique = sprintf( + "Total number of %s infusions", + study_agent + ) + ), + id_var = "USUBJID" + ) + ) |> + analyze( + "infusarn_neg_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 2L, + section_div = " ", + extra_args = list( + .stats = "ratio_unique", + .labels = c( + ratio_unique = "Infusions with infusion-related reactions~[super e], n (%)" + ), + denom_by = "infusan_neg_flg", + id_var = "USUBJID" + ) + ) + +# Section --- Create Table Shell ------------ + +result <- build_table(lyt, adishum, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirada02b.R b/tests/testthat/source_code/tirada02b.R new file mode 100644 index 00000000..fcbf5a3e --- /dev/null +++ b/tests/testthat/source_code/tirada02b.R @@ -0,0 +1,535 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRADA02b" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "SAFFL" # Safety Analysis Set flag +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +parqual_value <- "XANOMELINE" +ae_filter_exp <- expr(toupper(AESCAT) == toupper("infusion site reaction")) # user sets this to match ADAE.AESCAT +sev_grade_fl <- "AESEV" +# sev_grade_fl <- "AETOXGRN" +sev_grade_lbl <- "severe" +# sev_grade_lbl <- ">=grade 3" +adexsum_tnumd_paramcd <- "TNUMDOS" # set to TNUMDSSx as needed +dosedt_var <- "DOSEDT" # set to DOSSxDT as needed +combined_colspan_trt <- TRUE +include_ctrl_grp <- FALSE # set to FALSE to exclude control group (e.g. Placebo) from the table +study_agent <- "active study agent" +agent_antibody_label <- sprintf("antibodies to %s", study_agent) + +################################################################################ +# Process data: +################################################################################ + +# create filter for severity +sev_filter_exp <- if (sev_grade_fl == "AESEV") { + expr(toupper(!!sym(sev_grade_fl)) == toupper(sev_grade_lbl)) +} else { + expr(!!sym(sev_grade_fl) >= 3) +} + +# Read all raw datasets once; apply only population/key filters here +adsl_raw <- adsl_jnj |> + filter(.data[[popfl]] == "Y") + +adishum_raw <- adishum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARQUAL) == toupper(parqual_value) + ) + +adae_raw <- adae_jnj |> + filter( + .data[[popfl]] == "Y", + !!ae_filter_exp + ) + +adexsum_raw <- adexsum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARAMCD) == toupper(adexsum_tnumd_paramcd) + ) |> + select(USUBJID, INFUSAN = AVAL) + +# ADSL: Derive analysis-ready adsl with colspan variable +adsl <- adsl_raw |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + select( + USUBJID, + all_of(trtvar), + colspan_trt + ) + +# ADISHUM: one row per subject; derive antibody status flags and carry IMEVFL +adishum <- adishum_raw |> + select(USUBJID, ADATRES, IMEVFL) |> + filter(!is.na(ADATRES)) |> + distinct(USUBJID, .keep_all = TRUE) |> + mutate( + adatre_flg = if_else(toupper(ADATRES) == "POSITIVE", "Y", "N"), + adantre_flg = if_else(toupper(ADATRES) == "NEGATIVE", "Y", "N") + ) |> + select(USUBJID, adatre_flg, adantre_flg, IMEVFL) + +# ADAE: subject-level flags (distinct USUBJID per flag) +# NOTE: always count distinct subjects after subsetting on AESCAT + ADATRES + applicable attribute +adae_irr <- adae_raw |> + distinct(USUBJID) |> + mutate(infureact_flg = "Y") # any infusion site reaction + +# Purpose: flag subjects meeting severity/grade threshold per sev_filter_exp +adae_sev <- adae_raw |> + filter(!!sev_filter_exp) |> + distinct(USUBJID) |> + mutate(sev_flg = "Y") + +adae_ser <- adae_raw |> + filter(toupper(AESER) == "Y") |> + distinct(USUBJID) |> + mutate(ser_flg = "Y") # AESER=Y + +adae_treat_discon <- adae_raw |> + filter(toupper(TRDISCFL) == "Y") |> + distinct(USUBJID) |> + mutate(treat_discon_flg = "Y") # TRDISCFL=Y + +adae_dosct <- adexsum_raw |> + select(USUBJID) |> + left_join( + adae_raw |> + group_by(USUBJID) |> + summarise( + n_dosedt_num = n_distinct(.data[[dosedt_var]], na.rm = TRUE), + .groups = "drop" + ), + by = "USUBJID" + ) |> + mutate(n_dosedt_num = if_else(is.na(n_dosedt_num), 0, n_dosedt_num)) + +# Final join: adsl -> adishum -> imevfl -> all adae flags -> adexsum +# Each auxiliary dataset has one row per subject — no many-to-many +join_list <- list( + adae_irr, + adae_sev, + adae_ser, + adae_treat_discon, + adae_dosct, + adexsum_raw +) + +adishum <- adsl |> + left_join(adishum, by = "USUBJID") |> + purrr::reduce(join_list, ~ left_join(.x, .y, by = "USUBJID"), .init = _) |> + distinct(USUBJID, .keep_all = TRUE) |> + mutate( + across( + c(infureact_flg, sev_flg, ser_flg, treat_discon_flg), + ~ if_else(is.na(.), "N", as.character(.)) + ) + ) + +# Section --- Build analysis flags from joined columns ------------ +# Section 1 --- Adatre Positive (Treatment-Emergent Antibody Positive) ------------ +adishum <- adishum |> + mutate( + # infureact_pos_flg: any infusion site reaction in adae (AESCAT filter already applied) + infureact_pos_flg = case_when( + adatre_flg == "Y" & infureact_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # sev_pos_flg: per sev_filter_exp + sev_pos_flg = case_when( + adatre_flg == "Y" & sev_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # ser_pos_flg: AESER=Y + ser_pos_flg = case_when( + adatre_flg == "Y" & ser_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # treat_discon_pos_flg: TRDISCFL=Y + treat_discon_pos_flg = case_when( + adatre_flg == "Y" & treat_discon_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # infusan_pos_flg: total infusions from ADEXSUM for positive subjects (denominator for footnote e) + infusan_pos_flg = if_else(adatre_flg == "Y", INFUSAN, NA_real_), + # infusarn_pos_flg: distinct infusion site reaction infusion dates for positive subjects (numerator for footnote e) + infusarn_pos_flg = if_else(adatre_flg == "Y", as.numeric(n_dosedt_num), NA_real_) + ) + +# Section 2 --- Adantre Negative (Treatment-Emergent Antibody Negative) ------------ +adishum <- adishum |> + mutate( + # infureact_neg_flg: any infusion site reaction in adae + infureact_neg_flg = case_when( + adantre_flg == "Y" & infureact_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # sev_neg_flg: per sev_filter_exp + sev_neg_flg = case_when( + adantre_flg == "Y" & sev_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # ser_neg_flg: AESER=Y + ser_neg_flg = case_when( + adantre_flg == "Y" & ser_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # treat_discon_neg_flg: TRDISCFL=Y + treat_discon_neg_flg = case_when( + adantre_flg == "Y" & treat_discon_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # infusan_neg_flg: total infusions from ADEXSUM for negative subjects (denominator for footnote e) + infusan_neg_flg = if_else( + adantre_flg == "Y", + INFUSAN, + NA_real_ + ), + # infusarn_neg_flg: distinct infusion site reaction infusion dates for negative subjects (numerator for footnote e) + infusarn_neg_flg = if_else( + adantre_flg == "Y", + as.numeric(n_dosedt_num), + NA_real_ + ) + ) + +# final output needs only these columns +adishum <- adishum |> + select( + USUBJID, + all_of(trtvar), + colspan_trt, + IMEVFL, + adatre_flg, + adantre_flg, + infureact_pos_flg, + sev_pos_flg, + ser_pos_flg, + treat_discon_pos_flg, + infusan_pos_flg, + infusarn_pos_flg, + infureact_neg_flg, + sev_neg_flg, + ser_neg_flg, + treat_discon_neg_flg, + infusan_neg_flg, + infusarn_neg_flg + ) |> + unique() + +# Section --- Prepare Rtables Helpers ------------ +# add the Combined column via split function +if (combined_colspan_trt) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline Low Dose", "Xanomeline High Dose") # UPDATE + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +# colspan map built from adsl, not adishum +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar +) + +if (!include_ctrl_grp) { + colspan_trt_map <- colspan_trt_map |> + filter(.data[[trtvar]] != ctrl_grp) +} + +################################################################################ +# Define layout and build table: +################################################################################ +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map( + map = colspan_trt_map + ) + ) |> + split_cols_by( + trtvar, + split_fun = mysplit + ) |> + analyze( + "IMEVFL", + afun = a_freq_j, + show_labels = "hidden", + section_div = " ", + extra_args = list( + label = "Subjects with evaluable samples~[super a]", + val = "Y", + .stats = c("count_unique") + ) + ) |> + # Section 1 --- Adatre Positive (Treatment-Emergent Antibody Positive) ------------ + analyze( + "adatre_flg", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects positive for treatment-emergent %s~[super b,d]", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "infureact_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "sev_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = sprintf( + "Subjects with %s infusion site reaction, n (%%)", + sev_grade_lbl + ), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "ser_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with serious infusion site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "treat_discon_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion site reaction leading to treatment discontinuation, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "infusan_pos_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + .stats = "sum_unique", + .labels = c( + sum_unique = sprintf( + "Total number of %s infusions", + study_agent + ) + ), + id_var = "USUBJID" + ) + ) |> + analyze( + "infusarn_pos_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 2L, + section_div = " ", + extra_args = list( + .stats = "ratio_unique", + .labels = c( + ratio_unique = "Infusions with infusion site reactions~[super e], n (%)" + ), + denom_by = "infusan_pos_flg", + id_var = "USUBJID" + ) + ) |> + # Section 2 --- Adantre Negative (Treatment-Emergent Antibody Negative) ------------ + analyze( + "adantre_flg", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects negative for treatment-emergent %s~[super c,d]", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "infureact_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "sev_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = sprintf( + "Subjects with %s infusion site reaction, n (%%)", + sev_grade_lbl + ), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "ser_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with serious infusion site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "treat_discon_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion site reaction leading to treatment discontinuation, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "infusan_neg_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + .stats = "sum_unique", + .labels = c( + sum_unique = sprintf( + "Total number of %s infusions", + study_agent + ) + ), + id_var = "USUBJID" + ) + ) |> + analyze( + "infusarn_neg_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 2L, + section_div = " ", + extra_args = list( + .stats = "ratio_unique", + .labels = c( + ratio_unique = "Infusions with infusion site reactions~[super e], n (%)" + ), + denom_by = "infusan_neg_flg", + id_var = "USUBJID" + ) + ) + +# Section --- Create Table Shell ------------ + +result <- build_table(lyt, adishum, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirada02btiter.R b/tests/testthat/source_code/tirada02btiter.R new file mode 100644 index 00000000..c12917ec --- /dev/null +++ b/tests/testthat/source_code/tirada02btiter.R @@ -0,0 +1,332 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRADA02b_titer" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "SAFFL" # Safety Analysis Set flag +parqual_value <- "XANOMELINE" +ae_filter_exp <- expr(toupper(AESCAT) == toupper("infusion site reaction")) # user sets this to match ADAE.AESCAT +sev_grade_fl <- "AESEV" +# sev_grade_fl <- "AETOXGRN" +sev_grade_lbl <- "severe" +# sev_grade_lbl <- ">=grade 3" +adexsum_tnumd_paramcd <- "TNUMDOS" # set to TNUMDSSx as needed +dosedt_var <- "DOSEDT" # set to DOSSxDT as needed +study_agent <- "active study agent" + +################################################################################ +# Process data: +################################################################################ + +# create filter for severity +sev_filter_exp <- if (sev_grade_fl == "AESEV") { + expr(toupper(!!sym(sev_grade_fl)) == toupper(sev_grade_lbl)) +} else { + expr(!!sym(sev_grade_fl) >= 3) +} + +adsl_raw <- adsl_jnj |> + filter(.data[[popfl]] == "Y") + +adishum_raw <- adishum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARQUAL) == toupper(parqual_value) + ) + +adae_raw <- adae_jnj |> + filter( + .data[[popfl]] == "Y", + !!ae_filter_exp + ) + +adexsum_raw <- adexsum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARAMCD) == toupper(adexsum_tnumd_paramcd) + ) |> + select(USUBJID, INFUSAN = AVAL) + +# defining column labels and levels +neg_lbl <- sprintf( + "Negative for Treatment-emergent Antibodies to %s~[super a]", + study_agent +) +pos_lbl <- sprintf( + "Positive for Treatment-emergent Antibodies to %s~[super b]", + study_agent +) +titer_lbl <- sprintf( + "Peak Titers for Subjects Positive for Treatment-emergent Antibodies to %s", + study_agent +) +adatrept_lvl <- c("<10", "10 to <100", "100 to <1000", ">=1000") + +# Section --- Build column split variables ------------ + +# Subjects negative for treatment-emergent antibodies +neg_col_df <- adishum_raw |> + filter(toupper(ADATRES) == "NEGATIVE") |> + select(USUBJID) |> + mutate(neg_col = neg_lbl) |> + unique() + +# Subjects positive for treatment-emergent antibodies +pos_col_df <- adishum_raw |> + filter(toupper(ADATRES) == "POSITIVE") |> + select(USUBJID) |> + mutate(pos_col = pos_lbl) |> + unique() + +# Peak titer category column format +titer_col_df <- adishum_raw |> + select(USUBJID, ADATREPT) |> + mutate( + titer_col = if_else(!is.na(ADATREPT), titer_lbl, NA_character_), + ADATREPT = factor(ADATREPT, levels = adatrept_lvl) + ) |> + distinct(USUBJID, .keep_all = TRUE) + +# ADSL: attach col split vars for column layout; used as alt_counts_df +adsl <- adsl_raw |> + select(USUBJID) |> + left_join(neg_col_df, by = "USUBJID") |> + left_join(pos_col_df, by = "USUBJID") |> + left_join(titer_col_df, by = "USUBJID") + +# Section --- ADISHUM: one row per subject; carry IMEVFL ------------ +adishum <- adishum_raw |> + select(USUBJID, IMEVFL) |> + filter(IMEVFL == "Y") |> + distinct(USUBJID, .keep_all = TRUE) + +# Section --- ADAE: subject-level flags (distinct USUBJID per flag) ------------ +# NOTE: always count distinct subjects after subsetting on AESCAT + applicable attribute +adae_irr <- adae_raw |> + distinct(USUBJID) |> + mutate(infureact_flg = "Y") # any infusion site reaction + +# Purpose: flag subjects meeting severity/grade threshold per sev_filter_exp +adae_sev <- adae_raw |> + filter(!!sev_filter_exp) |> + distinct(USUBJID) |> + mutate(sev_flg = "Y") + +adae_ser <- adae_raw |> + filter(toupper(AESER) == "Y") |> + distinct(USUBJID) |> + mutate(ser_flg = "Y") # AESER=Y + +adae_treat_discon <- adae_raw |> + filter(toupper(TRDISCFL) == "Y") |> + distinct(USUBJID) |> + mutate(treat_discon_flg = "Y") # TRDISCFL=Y + +adae_dosct <- adexsum_raw |> + select(USUBJID) |> + left_join( + adae_raw |> + group_by(USUBJID) |> + summarise( + n_dosedt_num = n_distinct(.data[[dosedt_var]], na.rm = TRUE), + .groups = "drop" + ), + by = "USUBJID" + ) |> + mutate(n_dosedt_num = if_else(is.na(n_dosedt_num), 0, n_dosedt_num)) + +# Section --- Final join: adsl -> adishum -> adae flags -> adexsum ------------ +# Each auxiliary dataset is already one row per subject — no many-to-many risk +# adishum: distinct(USUBJID) above; adae_*: distinct(USUBJID) per flag; +# adae_dosct: one row per subject from adexsum_raw spine; adexsum_raw: select(USUBJID, INFUSAN) +join_list <- list( + adishum, + adae_irr, + adae_sev, + adae_ser, + adae_treat_discon, + adae_dosct, + adexsum_raw +) + +adishum <- adsl |> + purrr::reduce( + join_list, + ~ left_join(.x, .y, by = "USUBJID"), + .init = _ + ) |> + mutate( + across( + c(infureact_flg, sev_flg, ser_flg, treat_discon_flg), + ~ if_else(is.na(.), "N", as.character(.)) + ), + # infusan_num_flg: total active agent infusions from adexsum (denominator footnote e) + infusan_num_flg = INFUSAN, + # infusarn_num_flg: distinct infusion site reaction infusion dates (numerator footnote e) + infusarn_num_flg = as.numeric(n_dosedt_num) + ) |> + select( + USUBJID, + IMEVFL, + infureact_flg, + sev_flg, + ser_flg, + treat_discon_flg, + infusan_num_flg, + infusarn_num_flg, + neg_col, + pos_col, + titer_col, + ADATREPT + ) |> + unique() + +################################################################################ +# Define layout and build table: +################################################################################ +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + var = "neg_col", + split_fun = keep_split_levels(only = neg_lbl), + nested = FALSE + ) |> + split_cols_by( + var = "pos_col", + split_fun = keep_split_levels(only = pos_lbl), + nested = FALSE + ) |> + split_cols_by( + var = "titer_col", + split_fun = keep_split_levels(only = titer_lbl), + nested = FALSE + ) |> + split_cols_by( + var = "ADATREPT" + ) |> + analyze( + "IMEVFL", + afun = a_freq_j, + show_labels = "hidden", + section_div = " ", + extra_args = list( + label = "Subjects with evaluable samples~[super c]", + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "infureact_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion site reaction~[super d], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "sev_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = sprintf( + "Subjects with %s infusion site reaction~[super d], n (%%)", + sev_grade_lbl + ), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "ser_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with serious infusion site reaction~[super d], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "treat_discon_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion site reaction leading to treatment discontinuation~[super d], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "infusan_num_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + .stats = "sum_unique", + .labels = c( + sum_unique = sprintf( + "Total number of %s infusions", + study_agent + ) + ), + id_var = "USUBJID" + ) + ) |> + analyze( + "infusarn_num_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 2L, + extra_args = list( + .stats = "ratio_unique", + .labels = c( + ratio_unique = "Infusions with infusion site reactions~[super e], n (%)" + ), + denom_by = "infusan_num_flg", + id_var = "USUBJID" + ) + ) + +# Section --- Create Table Shell ------------ + +result <- build_table(lyt, adishum, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirada02titer.R b/tests/testthat/source_code/tirada02titer.R new file mode 100644 index 00000000..00fba14c --- /dev/null +++ b/tests/testthat/source_code/tirada02titer.R @@ -0,0 +1,332 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRADA02titer" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "SAFFL" # Safety Analysis Set flag +parqual_value <- "XANOMELINE" +ae_filter_exp <- expr(toupper(AESCAT) == toupper("infusion related reaction")) # user sets this to match ADAE.AESCAT +sev_grade_fl <- "AESEV" +# sev_grade_fl <- "AETOXGRN" +sev_grade_lbl <- "severe" +# sev_grade_lbl <- ">=grade 3" +adexsum_tnumd_paramcd <- "TNUMDOS" # set to TNUMDSSx as needed +dosedt_var <- "DOSEDT" # set to DOSSxDT as needed +study_agent <- "active study agent" + +################################################################################ +# Process data: +################################################################################ + +# create filter for severity +sev_filter_exp <- if (sev_grade_fl == "AESEV") { + expr(toupper(!!sym(sev_grade_fl)) == toupper(sev_grade_lbl)) +} else { + expr(!!sym(sev_grade_fl) >= 3) +} + +adsl_raw <- adsl_jnj |> + filter(.data[[popfl]] == "Y") + +adishum_raw <- adishum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARQUAL) == toupper(parqual_value) + ) + +adae_raw <- adae_jnj |> + filter( + .data[[popfl]] == "Y", + !!ae_filter_exp + ) + +adexsum_raw <- adexsum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARAMCD) == toupper(adexsum_tnumd_paramcd) + ) |> + select(USUBJID, INFUSAN = AVAL) + +# defining column labels and levels +neg_lbl <- sprintf( + "Negative for Treatment-emergent Antibodies to %s~[super a]", + study_agent +) +pos_lbl <- sprintf( + "Positive for Treatment-emergent Antibodies to %s~[super b]", + study_agent +) +titer_lbl <- sprintf( + "Peak Titers for Subjects Positive for Treatment-emergent Antibodies to %s", + study_agent +) +adatrept_lvl <- c("<10", "10 to <100", "100 to <1000", ">=1000") + +# Section --- Build column split variables ------------ + +# Subjects negative for treatment-emergent antibodies +neg_col_df <- adishum_raw |> + filter(toupper(ADATRES) == "NEGATIVE") |> + select(USUBJID) |> + mutate(neg_col = neg_lbl) |> + unique() + +# Subjects positive for treatment-emergent antibodies +pos_col_df <- adishum_raw |> + filter(toupper(ADATRES) == "POSITIVE") |> + select(USUBJID) |> + mutate(pos_col = pos_lbl) |> + unique() + +# Peak titer category column format +titer_col_df <- adishum_raw |> + select(USUBJID, ADATREPT) |> + mutate( + titer_col = if_else(!is.na(ADATREPT), titer_lbl, NA_character_), + ADATREPT = factor(ADATREPT, levels = adatrept_lvl) + ) |> + distinct(USUBJID, .keep_all = TRUE) + +# ADSL: attach col split vars for column layout; used as alt_counts_df +adsl <- adsl_raw |> + select(USUBJID) |> + left_join(neg_col_df, by = "USUBJID") |> + left_join(pos_col_df, by = "USUBJID") |> + left_join(titer_col_df, by = "USUBJID") + +# Section --- ADISHUM: one row per subject; carry IMEVFL ------------ +adishum <- adishum_raw |> + select(USUBJID, IMEVFL) |> + filter(IMEVFL == "Y") |> + distinct(USUBJID, .keep_all = TRUE) + +# Section --- ADAE: subject-level flags (distinct USUBJID per flag) ------------ +# NOTE: always count distinct subjects after subsetting on AESCAT + applicable attribute +adae_irr <- adae_raw |> + distinct(USUBJID) |> + mutate(infureact_flg = "Y") # any infusion-related reaction + +# Purpose: flag subjects meeting severity/grade threshold per sev_filter_exp +adae_sev <- adae_raw |> + filter(!!sev_filter_exp) |> + distinct(USUBJID) |> + mutate(sev_flg = "Y") + +adae_ser <- adae_raw |> + filter(toupper(AESER) == "Y") |> + distinct(USUBJID) |> + mutate(ser_flg = "Y") # AESER=Y + +adae_treat_discon <- adae_raw |> + filter(toupper(TRDISCFL) == "Y") |> + distinct(USUBJID) |> + mutate(treat_discon_flg = "Y") # TRDISCFL=Y + +adae_dosct <- adexsum_raw |> + select(USUBJID) |> + left_join( + adae_raw |> + group_by(USUBJID) |> + summarise( + n_dosedt_num = n_distinct(.data[[dosedt_var]], na.rm = TRUE), + .groups = "drop" + ), + by = "USUBJID" + ) |> + mutate(n_dosedt_num = if_else(is.na(n_dosedt_num), 0, n_dosedt_num)) + +# Section --- Final join: adsl -> adishum -> adae flags -> adexsum ------------ +# Each auxiliary dataset is already one row per subject — no many-to-many risk +# adishum: distinct(USUBJID) above; adae_*: distinct(USUBJID) per flag; +# adae_dosct: one row per subject from adexsum_raw spine; adexsum_raw: select(USUBJID, INFUSAN) +join_list <- list( + adishum, + adae_irr, + adae_sev, + adae_ser, + adae_treat_discon, + adae_dosct, + adexsum_raw +) + +adishum <- adsl |> + purrr::reduce( + join_list, + ~ left_join(.x, .y, by = "USUBJID"), + .init = _ + ) |> + mutate( + across( + c(infureact_flg, sev_flg, ser_flg, treat_discon_flg), + ~ if_else(is.na(.), "N", as.character(.)) + ), + # infusan_num_flg: total active agent infusions from adexsum (denominator footnote e) + infusan_num_flg = INFUSAN, + # infusarn_num_flg: distinct IRR infusion dates (numerator footnote e) + infusarn_num_flg = as.numeric(n_dosedt_num) + ) |> + select( + USUBJID, + IMEVFL, + infureact_flg, + sev_flg, + ser_flg, + treat_discon_flg, + infusan_num_flg, + infusarn_num_flg, + neg_col, + pos_col, + titer_col, + ADATREPT + ) |> + unique() + +################################################################################ +# Define layout and build table: +################################################################################ +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + var = "neg_col", + split_fun = keep_split_levels(only = neg_lbl), + nested = FALSE + ) |> + split_cols_by( + var = "pos_col", + split_fun = keep_split_levels(only = pos_lbl), + nested = FALSE + ) |> + split_cols_by( + var = "titer_col", + split_fun = keep_split_levels(only = titer_lbl), + nested = FALSE + ) |> + split_cols_by( + var = "ADATREPT" + ) |> + analyze( + "IMEVFL", + afun = a_freq_j, + show_labels = "hidden", + section_div = " ", + extra_args = list( + label = "Subjects with evaluable samples~[super c]", + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "infureact_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion-related reaction~[super d], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "sev_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = sprintf( + "Subjects with %s infusion-related reaction~[super d], n (%%)", + sev_grade_lbl + ), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "ser_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with serious infusion-related reaction~[super d], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "treat_discon_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with infusion-related reaction leading to treatment discontinuation~[super d], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "infusan_num_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + .stats = "sum_unique", + .labels = c( + sum_unique = sprintf( + "Total number of %s infusions", + study_agent + ) + ), + id_var = "USUBJID" + ) + ) |> + analyze( + "infusarn_num_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 2L, + extra_args = list( + .stats = "ratio_unique", + .labels = c( + ratio_unique = "Infusions with infusion-related reactions~[super e], n (%)" + ), + denom_by = "infusan_num_flg", + id_var = "USUBJID" + ) + ) + +# Section --- Create Table Shell ------------ + +result <- build_table(lyt, adishum, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirada03.R b/tests/testthat/source_code/tirada03.R new file mode 100644 index 00000000..02e5da7d --- /dev/null +++ b/tests/testthat/source_code/tirada03.R @@ -0,0 +1,553 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRADA03" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "SAFFL" # Safety Analysis Set flag +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +parqual_value <- "XANOMELINE" +ae_filter_exp <- expr(toupper(AESCAT) == toupper("injection site reaction")) # user sets this to match ADAE.AESCAT +sev_grade_fl <- "AESEV" +# sev_grade_fl <- "AETOXGRN" +sev_grade_lbl <- "severe" +# sev_grade_lbl <- ">=grade 3" +adexsum_tnumd_paramcd <- "TNUMDOS" # set to TNUMDSSx as needed +dosedt_var <- "DOSEDT" # set to DOSSxDT as needed +combined_colspan_trt <- TRUE +include_ctrl_grp <- FALSE # set to FALSE to exclude control group (e.g. Placebo) from the table +study_agent <- "active study agent" +agent_antibody_label <- sprintf("antibodies to %s", study_agent) + +################################################################################ +# Process data: +################################################################################ + +# create filter for severity +sev_filter_exp <- if (sev_grade_fl == "AESEV") { + expr(toupper(!!sym(sev_grade_fl)) == toupper(sev_grade_lbl)) +} else { + expr(!!sym(sev_grade_fl) >= 3) +} + +# Read all raw datasets once; apply only population/key filters here +adsl_raw <- adsl_jnj |> + filter(.data[[popfl]] == "Y") + +adishum_raw <- adishum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARQUAL) == toupper(parqual_value) + ) + +adae_raw <- adae_jnj |> + filter( + .data[[popfl]] == "Y", + !!ae_filter_exp + ) + +adexsum_raw <- adexsum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARAMCD) == toupper(adexsum_tnumd_paramcd) + ) |> + select(USUBJID, INJECAN = AVAL) + +# ADSL: Derive analysis-ready adsl with colspan variable +adsl <- adsl_raw |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + select( + USUBJID, + all_of(trtvar), + colspan_trt + ) + +# ADISHUM: one row per subject; derive antibody status flags and carry IMEVFL +adishum <- adishum_raw |> + select(USUBJID, ADATRES, IMEVFL) |> + filter(!is.na(ADATRES)) |> + distinct(USUBJID, .keep_all = TRUE) |> + mutate( + adatre_flg = if_else(toupper(ADATRES) == "POSITIVE", "Y", "N"), + adantre_flg = if_else(toupper(ADATRES) == "NEGATIVE", "Y", "N") + ) |> + select(USUBJID, adatre_flg, adantre_flg, IMEVFL) + +# ADAE: subject-level flags (distinct USUBJID per flag) +# NOTE: always count distinct subjects after subsetting on AESCAT + applicable attribute +adae_irr <- adae_raw |> + distinct(USUBJID) |> + mutate(injureact_flg = "Y") # any injection site reaction + +# Purpose: flag subjects meeting severity/grade threshold per sev_filter_exp +adae_sev <- adae_raw |> + filter(!!sev_filter_exp) |> + distinct(USUBJID) |> + mutate(sev_flg = "Y") + +adae_ser <- adae_raw |> + filter(toupper(AESER) == "Y") |> + distinct(USUBJID) |> + mutate(ser_flg = "Y") # AESER=Y + +adae_treat_discon <- adae_raw |> + filter(toupper(TRDISCFL) == "Y") |> + distinct(USUBJID) |> + mutate(treat_discon_flg = "Y") # TRDISCFL=Y + +adae_dosct <- adexsum_raw |> + select(USUBJID) |> + left_join( + adae_raw |> + group_by(USUBJID) |> + summarise( + n_dosedt_num = n_distinct(.data[[dosedt_var]], na.rm = TRUE), + .groups = "drop" + ), + by = "USUBJID" + ) |> + mutate(n_dosedt_num = if_else(is.na(n_dosedt_num), 0, n_dosedt_num)) + +# Final join: adsl -> adishum -> all adae flags -> adexsum +# Each auxiliary dataset has one row per subject — no many-to-many +join_list <- list( + adae_irr, + adae_sev, + adae_ser, + adae_treat_discon, + adae_dosct, + adexsum_raw +) + +adishum <- adsl |> + left_join(adishum, by = "USUBJID") |> + purrr::reduce(join_list, ~ left_join(.x, .y, by = "USUBJID"), .init = _) |> + distinct(USUBJID, .keep_all = TRUE) |> + mutate( + across( + c(injureact_flg, sev_flg, ser_flg, treat_discon_flg), + ~ if_else(is.na(.), "N", as.character(.)) + ) + ) + +# Section --- Build analysis flags from joined columns ------------ +# Section 1 --- Adatre Positive (Treatment-Emergent Antibody Positive) ------------ +adishum <- adishum |> + mutate( + # injureact_pos_flg: any injection site reaction in adae (AESCAT filter already applied) + injureact_pos_flg = case_when( + adatre_flg == "Y" & injureact_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # sev_pos_flg: per sev_filter_exp + sev_pos_flg = case_when( + adatre_flg == "Y" & sev_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # ser_pos_flg: AESER=Y + ser_pos_flg = case_when( + adatre_flg == "Y" & ser_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # treat_discon_pos_flg: TRDISCFL=Y + treat_discon_pos_flg = case_when( + adatre_flg == "Y" & treat_discon_flg == "Y" ~ "Y", + adatre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # injecan_pos_num_flg: total injections from ADEXSUM for positive subjects (denominator for footnote e) + injecan_pos_num_flg = if_else( + adatre_flg == "Y", + INJECAN, + NA_real_ + ), + # injecarn_pos_num_flg: distinct injection site reaction dates for positive subjects (numerator for footnote e) + injecarn_pos_num_flg = if_else( + adatre_flg == "Y", + as.numeric(n_dosedt_num), + NA_real_ + ) + ) + +# Section 2 --- Adantre Negative (Treatment-Emergent Antibody Negative) ------------ +adishum <- adishum |> + mutate( + # injureact_neg_flg: any injection site reaction in adae + injureact_neg_flg = case_when( + adantre_flg == "Y" & injureact_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # sev_neg_flg: per sev_filter_exp + sev_neg_flg = case_when( + adantre_flg == "Y" & sev_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # ser_neg_flg: AESER=Y + ser_neg_flg = case_when( + adantre_flg == "Y" & ser_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # treat_discon_neg_flg: TRDISCFL=Y + treat_discon_neg_flg = case_when( + adantre_flg == "Y" & treat_discon_flg == "Y" ~ "Y", + adantre_flg == "Y" ~ "N", + TRUE ~ NA_character_ + ), + # injecan_neg_num_flg: total injections from ADEXSUM for negative subjects (denominator for footnote e) + injecan_neg_num_flg = if_else( + adantre_flg == "Y", + INJECAN, + NA_real_ + ), + # injecarn_neg_num_flg: distinct injection site reaction dates for negative subjects (numerator for footnote e) + injecarn_neg_num_flg = if_else( + adantre_flg == "Y", + as.numeric(n_dosedt_num), + NA_real_ + ) + ) + +# final output needs only these columns +adishum <- adishum |> + select( + USUBJID, + all_of(trtvar), + colspan_trt, + IMEVFL, + # positive section flags + adatre_flg, + injureact_pos_flg, + sev_pos_flg, + ser_pos_flg, + treat_discon_pos_flg, + injecan_pos_num_flg, + injecarn_pos_num_flg, + # negative section flags + adantre_flg, + injureact_neg_flg, + sev_neg_flg, + ser_neg_flg, + treat_discon_neg_flg, + injecan_neg_num_flg, + injecarn_neg_num_flg + ) |> + unique() + +# Section --- Prepare Rtables Helpers ------------ +# add the Combined column via split function +if (combined_colspan_trt) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline Low Dose", "Xanomeline High Dose") # UPDATE + ) + + # remove Combined from Placebo spanning header + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun( + post = list(add_combo, rm_combo_from_placebo) + ) +} + +# colspan map built from adsl, not adishum +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar +) + +# remove control group from map if not needed +if (!include_ctrl_grp) { + colspan_trt_map <- colspan_trt_map |> + filter(.data[[trtvar]] != ctrl_grp) +} + +################################################################################ +# Define layout and build table: +################################################################################ +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + # first level header: Active Study Agent vs Placebo + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map( + map = colspan_trt_map + ) + ) |> + # second level header: individual treatment groups + Combined + split_cols_by( + trtvar, + split_fun = mysplit + ) |> + # evaluable samples row: N only, no percentage + analyze( + "IMEVFL", + afun = a_freq_j, + show_labels = "hidden", + section_div = " ", + extra_args = list( + label = "Subjects with evaluable samples~[super a]", + val = "Y", + .stats = c("count_unique") + ) + ) |> + # Section 1 --- Adatre Positive (Treatment-Emergent Antibody Positive) ------------ + analyze( + "adatre_flg", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects positive for treatment-emergent %s~[super b,d]", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "injureact_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with injection site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "sev_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = sprintf( + "Subjects with %s injection site reaction, n (%%)", + sev_grade_lbl + ), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "ser_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with serious injection site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "treat_discon_pos_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with injection site reaction leading to treatment discontinuation, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "injecan_pos_num_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + .stats = "sum_unique", + .labels = c( + sum_unique = sprintf( + "Total number of %s injections", + study_agent + ) + ), + id_var = "USUBJID" + ) + ) |> + analyze( + "injecarn_pos_num_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 2L, + section_div = " ", + extra_args = list( + .stats = "ratio_unique", + .labels = c( + ratio_unique = "Injections with injection site reactions~[super e], n (%)" + ), + denom_by = "injecan_pos_num_flg", + id_var = "USUBJID" + ) + ) |> + # Section 2 --- Adantre Negative (Treatment-Emergent Antibody Negative) ------------ + analyze( + "adantre_flg", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects negative for treatment-emergent %s~[super c,d]", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "injureact_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with injection site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "sev_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = sprintf( + "Subjects with %s injection site reaction, n (%%)", + sev_grade_lbl + ), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "ser_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with serious injection site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "treat_discon_neg_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with injection site reaction leading to treatment discontinuation, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + # injection counts: denominator = total injections in respective column + analyze( + "injecan_neg_num_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + .stats = "sum_unique", + .labels = c( + sum_unique = sprintf( + "Total number of %s injections", + study_agent + ) + ), + id_var = "USUBJID" + ) + ) |> + analyze( + "injecarn_neg_num_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 2L, + section_div = " ", + extra_args = list( + .stats = "ratio_unique", + .labels = c( + ratio_unique = "Injections with injection site reactions~[super e], n (%)" + ), + denom_by = "injecan_neg_num_flg", + id_var = "USUBJID" + ) + ) + +# Section --- Create Table Shell ------------ + +result <- build_table(lyt, adishum, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirada03titer.R b/tests/testthat/source_code/tirada03titer.R new file mode 100644 index 00000000..931b7c4a --- /dev/null +++ b/tests/testthat/source_code/tirada03titer.R @@ -0,0 +1,332 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRADA03titer" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "SAFFL" # Safety Analysis Set flag +parqual_value <- "XANOMELINE" +ae_filter_exp <- expr(toupper(AESCAT) == toupper("injection site reaction")) # user sets this to match ADAE.AESCAT +sev_grade_fl <- "AESEV" +# sev_grade_fl <- "AETOXGRN" +sev_grade_lbl <- "severe" +# sev_grade_lbl <- ">=grade 3" +adexsum_tnumd_paramcd <- "TNUMDOS" # set to TNUMDSSx as needed +dosedt_var <- "DOSEDT" # set to DOSSxDT as needed +study_agent <- "active study agent" + +################################################################################ +# Process data: +################################################################################ + +# create filter for severity +sev_filter_exp <- if (sev_grade_fl == "AESEV") { + expr(toupper(!!sym(sev_grade_fl)) == toupper(sev_grade_lbl)) +} else { + expr(!!sym(sev_grade_fl) >= 3) +} + +adsl_raw <- adsl_jnj |> + filter(.data[[popfl]] == "Y") + +adishum_raw <- adishum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARQUAL) == toupper(parqual_value) + ) + +adae_raw <- adae_jnj |> + filter( + .data[[popfl]] == "Y", + !!ae_filter_exp + ) + +adexsum_raw <- adexsum_jnj |> + filter( + .data[[popfl]] == "Y", + toupper(PARAMCD) == toupper(adexsum_tnumd_paramcd) + ) |> + select(USUBJID, INJECAN = AVAL) + +# defining column labels and levels +neg_lbl <- sprintf( + "Negative for Treatment-emergent Antibodies to %s~[super a]", + study_agent +) +pos_lbl <- sprintf( + "Positive for Treatment-emergent Antibodies to %s~[super b]", + study_agent +) +titer_lbl <- sprintf( + "Peak Titers for Subjects Positive for Treatment-emergent Antibodies to %s", + study_agent +) +adatrept_lvl <- c("<10", "10 to <100", "100 to <1000", ">=1000") + +# Section --- Build column split variables ------------ + +# Subjects negative for treatment-emergent antibodies +neg_col_df <- adishum_raw |> + filter(toupper(ADATRES) == "NEGATIVE") |> + select(USUBJID) |> + mutate(neg_col = neg_lbl) |> + unique() + +# Subjects positive for treatment-emergent antibodies +pos_col_df <- adishum_raw |> + filter(toupper(ADATRES) == "POSITIVE") |> + select(USUBJID) |> + mutate(pos_col = pos_lbl) |> + unique() + +# Peak titer category column format +titer_col_df <- adishum_raw |> + select(USUBJID, ADATREPT) |> + mutate( + titer_col = if_else(!is.na(ADATREPT), titer_lbl, NA_character_), + ADATREPT = factor(ADATREPT, levels = adatrept_lvl) + ) |> + distinct(USUBJID, .keep_all = TRUE) + +# ADSL: attach col split vars for column layout; used as alt_counts_df +adsl <- adsl_raw |> + select(USUBJID) |> + left_join(neg_col_df, by = "USUBJID") |> + left_join(pos_col_df, by = "USUBJID") |> + left_join(titer_col_df, by = "USUBJID") + +# Section --- ADISHUM: one row per subject; carry IMEVFL ------------ +adishum <- adishum_raw |> + select(USUBJID, IMEVFL) |> + filter(IMEVFL == "Y") |> + distinct(USUBJID, .keep_all = TRUE) + +# Section --- ADAE: subject-level flags (distinct USUBJID per flag) ------------ +# NOTE: always count distinct subjects after subsetting on AESCAT + applicable attribute +adae_irr <- adae_raw |> + distinct(USUBJID) |> + mutate(injureact_flg = "Y") # any injection site reaction + +# Purpose: flag subjects meeting severity/grade threshold per sev_filter_exp +adae_sev <- adae_raw |> + filter(!!sev_filter_exp) |> + distinct(USUBJID) |> + mutate(sev_flg = "Y") + +adae_ser <- adae_raw |> + filter(toupper(AESER) == "Y") |> + distinct(USUBJID) |> + mutate(ser_flg = "Y") # AESER=Y + +adae_treat_discon <- adae_raw |> + filter(toupper(TRDISCFL) == "Y") |> + distinct(USUBJID) |> + mutate(treat_discon_flg = "Y") # TRDISCFL=Y + +adae_dosct <- adexsum_raw |> + select(USUBJID) |> + left_join( + adae_raw |> + group_by(USUBJID) |> + summarise( + n_dosedt_num = n_distinct(.data[[dosedt_var]], na.rm = TRUE), + .groups = "drop" + ), + by = "USUBJID" + ) |> + mutate(n_dosedt_num = if_else(is.na(n_dosedt_num), 0, n_dosedt_num)) + +# Section --- Final join: adsl -> adishum -> adae flags -> adexsum ------------ +# Each auxiliary dataset is already one row per subject — no many-to-many risk +# adishum: distinct(USUBJID) above; adae_*: distinct(USUBJID) per flag; +# adae_dosct: one row per subject from adexsum_raw spine; adexsum_raw: select(USUBJID, INJECAN) +join_list <- list( + adishum, + adae_irr, + adae_sev, + adae_ser, + adae_treat_discon, + adae_dosct, + adexsum_raw +) + +adishum <- adsl |> + purrr::reduce( + join_list, + ~ left_join(.x, .y, by = "USUBJID"), + .init = _ + ) |> + mutate( + across( + c(injureact_flg, sev_flg, ser_flg, treat_discon_flg), + ~ if_else(is.na(.), "N", as.character(.)) + ), + # injecan_num_flg: total active agent injections from adexsum (denominator footnote e) + injecan_num_flg = INJECAN, + # injecarn_num_flg: distinct injection site reaction dates (numerator footnote e) + injecarn_num_flg = as.numeric(n_dosedt_num) + ) |> + select( + USUBJID, + IMEVFL, + injureact_flg, + sev_flg, + ser_flg, + treat_discon_flg, + injecan_num_flg, + injecarn_num_flg, + neg_col, + pos_col, + titer_col, + ADATREPT + ) |> + unique() + +################################################################################ +# Define layout and build table: +################################################################################ +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + var = "neg_col", + split_fun = keep_split_levels(only = neg_lbl), + nested = FALSE + ) |> + split_cols_by( + var = "pos_col", + split_fun = keep_split_levels(only = pos_lbl), + nested = FALSE + ) |> + split_cols_by( + var = "titer_col", + split_fun = keep_split_levels(only = titer_lbl), + nested = FALSE + ) |> + split_cols_by( + var = "ADATREPT" + ) |> + analyze( + "IMEVFL", + afun = a_freq_j, + show_labels = "hidden", + section_div = " ", + extra_args = list( + label = "Subjects with evaluable samples~[super c]", + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "injureact_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with injection site reaction~[super d], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "sev_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = sprintf( + "Subjects with %s injection site reaction~[super d], n (%%)", + sev_grade_lbl + ), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "ser_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with serious injection site reaction~[super d], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "treat_discon_flg", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with injection site reaction leading to treatment discontinuation~[super d], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_df" + ) + ) |> + analyze( + "injecan_num_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + .stats = "sum_unique", + .labels = c( + sum_unique = sprintf( + "Total number of %s injections", + study_agent + ) + ), + id_var = "USUBJID" + ) + ) |> + analyze( + "injecarn_num_flg", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 2L, + extra_args = list( + .stats = "ratio_unique", + .labels = c( + ratio_unique = "Injections with injection site reactions~[super e], n (%)" + ), + denom_by = "injecan_num_flg", + id_var = "USUBJID" + ) + ) + +# Section --- Create Table Shell ------------ + +result <- build_table(lyt, adishum, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirada06.R b/tests/testthat/source_code/tirada06.R new file mode 100644 index 00000000..9a69c5df --- /dev/null +++ b/tests/testthat/source_code/tirada06.R @@ -0,0 +1,339 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRADA06" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "IMFL" # Immunogenicity Analysis Set flag +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +parqual_value <- "XANOMELINE" +combined_colspan_trt <- TRUE +include_ctrl_grp <- FALSE # set to FALSE to exclude control group (e.g. Placebo) from the table +study_agent <- "active study agent" # study-specific name of the active study agent +agent_antibody_label <- sprintf("antibodies to %s", study_agent) + +# optional row flags: set to FALSE to hide the corresponding row(s) +add_adapsp_row <- TRUE # subjects with persistent ADA response (section 2) +add_adatsp_row <- TRUE # subjects with transient ADA response (section 3) +add_adaund_row <- TRUE # subjects with undetermined ADA response (section 4) +add_pspdurw_section <- TRUE # duration of persistent treatment-induced ADA (section 7) +add_cv <- TRUE # cv (%) row in all continuous summary sections +add_interquartile_range <- TRUE # interquartile range row in all continuous summary sections + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + select( + USUBJID, + all_of(trtvar), + colspan_trt + ) + +adishum_raw <- adishum_jnj + +adishum <- adishum_raw |> + filter( + toupper(PARQUAL) == toupper(parqual_value) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + +# left join from adsl to include all eligible subjects +# colspan_trt and trtvar (with factor levels) come from adsl +adishum <- adsl |> + left_join( + adishum |> + select(-all_of(trtvar)), + by = "USUBJID" + ) + +# Section --- Auxilary Datasets Needed For Final Dataset ------------ +# extract flag columns (one row per subject) and join onto adishum +flag_paramcds <- c("ADATRI", "ADAPSP", "ADATSP", "ADAUND") + +for (p in flag_paramcds) { + col_name <- tolower(p) + flag_df <- adishum |> + filter(PARAMCD == p) |> + select(USUBJID, !!col_name := AVALC) + + adishum <- adishum |> + left_join(flag_df, by = "USUBJID") |> + mutate( + !!col_name := if_else( + is.na(.data[[col_name]]), + "N", + .data[[col_name]] + ) + ) +} + +# continuous variables: one row per subject per PARAMCD, join AVAL onto adishum +cont_paramcds <- c("TMOSADAW", "ADADURW", "PSPDURW") + +for (p in cont_paramcds) { + col_name <- tolower(p) + cont_df <- adishum |> + filter(PARAMCD == p) |> + select(USUBJID, !!col_name := AVAL) + + adishum <- adishum |> + left_join(cont_df, by = "USUBJID") +} + +adishum <- adishum |> + select( + USUBJID, + all_of(trtvar), + colspan_trt, + adatri, + adapsp, + adatsp, + adaund, + tmosadaw, + adadurw, + pspdurw + ) |> + # remove all complete duplicate rows + unique() + +# Section --- Prepare Rtables Helpers ------------ +# add the Combined column via split function +if (combined_colspan_trt) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline Low Dose", "Xanomeline High Dose") # UPDATE + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +# colspan map built from adsl, not adishum +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar +) + +if (!include_ctrl_grp) { + colspan_trt_map <- colspan_trt_map |> + filter(.data[[trtvar]] != ctrl_grp) +} + +################################################################################ +# Define layout and build table: +################################################################################ +# shared extra_args for all continuous summary sections (sections 5, 6, 7) +# base stats always shown: n, mean (sd), median, min/max +cont_stats <- c("n", "mean_sd", "median", "range", if (add_cv) "cv", if (add_interquartile_range) "quantiles") + +# indent levels for each stat row (0 = flush with section header, 1 = indented) +cont_indent_mods <- c("n" = 0L, "mean_sd" = 1L, "median" = 1L, "range" = 1L, "cv" = 1L, "quantiles" = 1L) + +# display labels for stat rows that differ from rtables defaults +cont_labels <- c("n" = "N", "range" = "Min, max", "quantiles" = "Interquartile range") + +dp <- 1 +.formats_all <- junco:::fmt_spec_single_d( + d = dp, + stats_in = cont_stats, + fmt_d_def = junco_def_d_all, + fmt_d_in = NULL +) +fmt_details <- get_fmt_details(.formats_all, as_tibble = TRUE) + +multi_stat_summary_args <- list( + .stats = cont_stats, + .labels = cont_labels, + .formats = .formats_all, + .indent_mods = cont_indent_mods, + control = control_analyze_vars( + quantiles = c(0.25, 0.75), + quantile_type = 2 + ) +) + +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + # define column splits + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map( + map = colspan_trt_map + ) + ) |> + split_cols_by( + trtvar, + split_fun = mysplit + ) |> + # Section 1: treatment-induced flag row + analyze( + "adatri", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = sprintf( + "Subjects positive for treatment-induced %s~[super a]", + agent_antibody_label + ), + val = "Y", + .stats = c("count_unique") + ) + ) + +# Section 2: persistent ADA response +if (add_adapsp_row) { + lyt <- lyt |> + analyze( + "adapsp", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with persistent ADA response~[super b]", + val = "Y", + .stats = c("count_unique_fraction") + ) + ) +} + +# Section 3: transient ADA response +if (add_adatsp_row) { + lyt <- lyt |> + analyze( + "adatsp", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + label = "Subjects with transient ADA response~[super c]", + val = "Y", + .stats = c("count_unique_fraction") + ) + ) +} + +# Section 4: undetermined ADA response +if (add_adaund_row) { + lyt <- lyt |> + analyze( + "adaund", + afun = a_freq_j, + show_labels = "hidden", + indent_mod = 1L, + section_div = " ", + extra_args = list( + label = "Subjects with undetermined ADA response~[super d]", + val = "Y", + .stats = c("count_unique_fraction") + ) + ) +} + +lyt <- lyt |> + # Section 5: time to onset of treatment-induced ADA + analyze( + "tmosadaw", + afun = a_summary, + show_labels = "visible", + section_div = " ", + var_labels = "Time to onset of treatment-induced ADA~[super e], (weeks)", + extra_args = multi_stat_summary_args + ) |> + # Section 6: duration of treatment-induced ADA + analyze( + "adadurw", + afun = a_summary, + show_labels = "visible", + section_div = " ", + var_labels = "Duration of treatment-induced ADA~[super f], (weeks)", + extra_args = multi_stat_summary_args + ) + +# Section 7: duration of persistent treatment-induced ADA +if (add_pspdurw_section) { + lyt <- lyt |> + analyze( + "pspdurw", + afun = a_summary, + show_labels = "visible", + section_div = " ", + var_labels = "Duration of persistent treatment-induced ADA~[super b,f], (weeks)", + extra_args = multi_stat_summary_args + ) +} + +# Section --- Create Table Shell ------------ + +result <- build_table(lyt, adishum, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 31, 31, 31) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirada07.R b/tests/testthat/source_code/tirada07.R new file mode 100644 index 00000000..1a5b2dbb --- /dev/null +++ b/tests/testthat/source_code/tirada07.R @@ -0,0 +1,288 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRADA07" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "IMFL" # Immunogenicity Analysis Set flag +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +parqual_value <- "XANOMELINE" +combined_colspan_trt <- TRUE +include_ctrl_grp <- FALSE # set to FALSE to exclude control group (e.g. Placebo) from the table +study_specific_critical_var <- "AVAL" # continuous response variable (update per SAP) +study_agent <- "active study agent" + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = "Y", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + select( + USUBJID, + all_of(trtvar), + colspan_trt + ) + +adishum_raw <- adishum_jnj + +adishum <- adishum_raw |> + filter( + toupper(PARQUAL) == toupper(parqual_value) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + +# left join from adsl to include all eligible subjects +# colspan_trt and trtvar (with factor levels) come from adsl +adishum <- adsl |> + left_join( + adishum |> + select(-all_of(trtvar)), + by = "USUBJID" + ) + +# Section --- Auxilary Datasets Needed For Final Dataset ------------ + +# ordered time point levels from AVISIT + ATPT +avisit_atpt_lvls <- adishum |> + filter(!is.na(AVISIT), !is.na(ATPT)) |> + arrange(AVISITN, ATPTN) |> + mutate(AVISIT_ATPT = paste(AVISIT, ATPT, sep = " - ")) |> + pull(AVISIT_ATPT) |> + unique() + +# derive visit-level numerator and denominator vars masked to positive subgroup +adishum <- adishum |> + mutate( + AVISIT_ATPT = factor( + if_else(!is.na(AVISIT) & !is.na(ATPT), paste(AVISIT, ATPT, sep = " - "), NA_character_), + levels = avisit_atpt_lvls + ) + ) + +# Section 2 --- Subjects positive for treatment-emergent antibodies (ADATRI OR ADATRB) ------------ +# flag subjects with ADATRI=Y or ADATRB=Y (treatment-induced or treatment-boosted) +pos_subj <- adishum |> + filter( + (PARAMCD == "ADATRI" & AVALC == "Y") | + (PARAMCD == "ADATRB" & AVALC == "Y") + ) |> + select(USUBJID) |> + distinct() |> + mutate(adatri_b_flag = "Y") + +adishum <- adishum |> + left_join(pos_subj, by = "USUBJID") |> + mutate(adatri_b_flag = if_else(is.na(adatri_b_flag), "N", adatri_b_flag)) + +# Section ---- for calculating time point +time_point_filtered <- adishum |> + filter( + PARAMCD == "SUADAST" & AVALC == "POSITIVE" + ) |> + select(USUBJID, AVISIT, ATPT) |> + distinct() |> + mutate(pos_time_point_flag = factor("Y")) + +imevfl_pos_filtered <- adishum |> + filter( + IMEVFL == "Y" + ) |> + select(USUBJID, AVISIT, ATPT) |> + distinct() |> + mutate(imevfl_pos = factor("Y")) + +adishum <- adishum |> + left_join( + imevfl_pos_filtered, + by = c("USUBJID", "AVISIT", "ATPT") + ) |> + left_join( + time_point_filtered, + by = c("USUBJID", "AVISIT", "ATPT") + ) |> + mutate( + imevfl_pos = if_else(is.na(imevfl_pos), "N", "Y") |> + factor(levels = c("Y", "N")), + pos_time_point_flag = if_else(is.na(pos_time_point_flag), "N", " ") |> + factor(levels = c(" ", "N")) + ) + +# final output needs only these columns +adishum <- adishum |> + select( + USUBJID, + all_of(trtvar), # TRT01A + colspan_trt, # column split + adatri_b_flag, + pos_time_point_flag, + imevfl_pos, + AVISIT_ATPT + ) |> + unique() + +# Section --- Prepare Rtables Helpers ------------ +# add the Combined column via split function +if (combined_colspan_trt) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline Low Dose", "Xanomeline High Dose") # UPDATE + ) + + # remove Combined from Placebo spanning header + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = "Y", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +# colspan map built from adsl, not adishum +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = "Y", + active_grp_span_lbl = study_agent |> + stringi::stri_trans_totitle(), + colspan_var = "colspan_trt", + trt_var = trtvar +) + +# remove control group from map if not needed +if (!include_ctrl_grp) { + colspan_trt_map <- colspan_trt_map |> + filter(.data[[trtvar]] != ctrl_grp) +} + +################################################################################ +# Define layout and build table: +################################################################################ +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + append_topleft(c("Visit")) |> + # first level header: Active Study Agent vs Placebo + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map( + map = colspan_trt_map + ) + ) |> + # second level header: individual treatment groups + Combined + split_cols_by( + trtvar, + split_fun = mysplit + ) |> + # Section 2 --- Subjects positive for treatment-emergent antibodies ------------ + analyze( + "adatri_b_flag", + afun = a_freq_j, + show_labels = "hidden", + section_div = " ", + extra_args = list( + label = sprintf( + "Subjects positive for treatment-emergent antibodies to %s~[super a]", + study_agent + ), + val = "Y", + .stats = "count_unique" + ) + ) |> + # Section 3 --- Time points: n/N(%) per visit ------------ + split_rows_by( + "AVISIT_ATPT", + child_labels = "hidden" + ) |> + split_rows_by( + "imevfl_pos", + split_fun = keep_split_levels("Y"), + label_pos = "hidden", + child_labels = "hidden" + ) |> + analyze( + "pos_time_point_flag", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + drop_levels = FALSE, + val = " ", + denom = "n_df", + .stats = "count_unique_denom_fraction" + ) + ) + +# Section --- Create Table Shell ------------ + +result <- build_table(lyt, adishum, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Post-Processing: +################################################################################ + +# Section --- Move visit labels onto data rows ------------ +for (v in levels(adishum$AVISIT_ATPT)) { + label_at_path( + result, + path = c("AVISIT_ATPT", v, "imevfl_pos", "Y", "pos_time_point_flag", "count_unique_denom_fraction. ") + ) <- v +} + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 23, 23, 25) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirnab01.R b/tests/testthat/source_code/tirnab01.R new file mode 100644 index 00000000..979d476b --- /dev/null +++ b/tests/testthat/source_code/tirnab01.R @@ -0,0 +1,204 @@ +library(envsetup) +library(tern) +library(dplyr) +library(tidyr) +library(rtables) +library(junco) +library(forcats) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRNAB01" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "IMFL" +trtvar <- "TRT01A" +combined_colspan_trt <- TRUE +parqual <- "XANOMELINE" +# addon_filter <- expr(.data[[trtvar]] != "Placebo") # To be used with ADISHUM. If no filter needed +addon_filter <- expr(TRUE) +agt_antiagt_lbl <- "antibodies to active study agent" + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y", .data[[trtvar]] != "Placebo") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ), + {{ trtvar }} := fct_drop(.data[[trtvar]]) + ) |> + mutate(colspan_trt = "Active Study Agent") |> + select(USUBJID, all_of(trtvar), all_of(popfl), colspan_trt) + +adishum <- adishum_jnj |> + filter(.data[[popfl]] == "Y", PARQUAL == parqual, !!addon_filter) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ), + {{ trtvar }} := fct_drop(.data[[trtvar]]) + ) |> + select(USUBJID, all_of(trtvar), all_of(popfl), PARAMCD, AVALC) + +adishum_pivot <- adishum |> + filter(PARAMCD %in% c("ADATRE", "NABPOS", "NABNEG")) |> + pivot_wider( + id_cols = USUBJID, + names_from = PARAMCD, + values_from = AVALC + ) |> + mutate(NAB = ifelse(ADATRE == "Y" & (NABPOS == "Y" | NABNEG == "Y"), "Y", NA)) + +adishum <- adishum_pivot |> + right_join(adsl, by = "USUBJID") + +# programming note 3: check if any subjects positive per section + +has_adatre <- any(adishum$ADATRE == "Y", na.rm = TRUE) + +################################################################################ +# Create Layout: +################################################################################ + +lyt <- basic_table() |> + split_cols_by( + "colspan_trt", + split_fun = drop_split_levels + ) |> + append_topleft("NAb Status") + +if (combined_colspan_trt) { + lyt <- lyt |> + split_cols_by( + var = trtvar, + show_colcounts = TRUE, + colcount_format = "N=xx", + split_fun = add_overall_level("Combined", first = FALSE) + ) +} else { + lyt <- lyt |> + split_cols_by( + var = trtvar, + show_colcounts = TRUE, + colcount_format = "N=xx" + ) +} + +lyt <- lyt |> + analyze( + "ADATRE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = paste("Subjects positive for treatment-emergent", agt_antiagt_lbl, "at any time~[super a]"), + val = "Y", + .stats = c("count_unique") + ) + ) |> + split_rows_by("NAB", split_fun = remove_split_levels(c("N")), child_labels = "hidden") |> + analyze( + "NAB", + indent_mod = 1L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects evaluable for neutralizing antibodies~[super b]", + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "NABPOS", + indent_mod = 2L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects positive for neutralizing antibodies~[super c], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NAB" + ) + ) |> + analyze( + "NABNEG", + indent_mod = 2L, + afun = a_freq_j, + show_labels = "hidden", + section_div = " ", + extra_args = list( + label = "Subjects negative for neutralizing antibodies~[super d], n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NAB" + ) + ) |> + analyze( + "NABPOS", + table_names = "Overall_positive", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Overall incidence of subjects positive for neutralizing antibodies~[super e], n (%)", + val = "Y", + .stats = c("count_unique_fraction") + ) + ) |> + analyze( + "NABNEG", + table_names = "Overall_negative", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Overall incidence of subjects negative for neutralizing antibodies~[super e], n (%)", + val = "Y", + .stats = c("count_unique_fraction") + ) + ) + +################################################################################ +# Create Table Shell: +################################################################################ + +result <- build_table(lyt, adishum, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Post-Processing: +################################################################################ + +result <- safe_prune_table(result, prune_func = prune_empty_level) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirnab02.R b/tests/testthat/source_code/tirnab02.R new file mode 100644 index 00000000..397c6da5 --- /dev/null +++ b/tests/testthat/source_code/tirnab02.R @@ -0,0 +1,434 @@ +library(envsetup) +library(tern) +library(dplyr) +library(tidyr) +library(rtables) +library(junco) +library(forcats) +library(tidyselect) +library(purrr) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRNAB02" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "SAFFL" +trtvar <- "TRT01A" +combined_colspan_trt <- TRUE + +################################################################################ +# ADISHUM parameters/ filter criteria: +################################################################################ +parqual <- "XANOMELINE" +addon_filter <- expr(.data[[trtvar]] != "Placebo") # To be used with ADISHUM. +# addon_filter <- expr(TRUE) # If no filter required +agent_name <- "active study agent" +agt_antiagt_lbl <- "antibodies to active study agent" +sev_grade_fl <- "AESEV" +# sev_grade_fl <- "AETOXGRN" +sev_grade_lbl <- "severe" +# sev_grade_lbl <- ">=grade 3" + +ae_filter <- expr(SAFFL == "Y" & AESCAT == "Infusion related reaction") +aedosdtvar <- "DOSEDT" + +adexsum_filter <- expr(SAFFL == "Y") +adexsumprmcd <- "TNUMDOS" + +################################################################################ +# Process data: +################################################################################ + +# Pre-process ADSL + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y", .data[[trtvar]] != "Placebo") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ), + {{ trtvar }} := fct_drop(.data[[trtvar]]) + ) |> + mutate(colspan_trt = "Active Study Agent") |> + select(USUBJID, all_of(trtvar), all_of(popfl), colspan_trt) + +# Pre-process ADISHUM + +adishum <- adishum_jnj |> + filter(.data[[popfl]] == "Y", PARQUAL == parqual, !!addon_filter) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ), + {{ trtvar }} := fct_drop(.data[[trtvar]]) + ) |> + select( + USUBJID, + all_of(trtvar), + all_of(popfl), + PARAMCD, + AVALC + ) + +adishum_pivot <- adishum |> + filter(PARAMCD %in% c("ADATRE", "NABPOS", "NABNEG")) |> + pivot_wider( + id_cols = c(USUBJID), + names_from = PARAMCD, + values_from = AVALC + ) |> + mutate(NAB = ifelse(NABPOS == "Y" | NABNEG == "Y", "Y", NA)) + +adishum <- adishum_pivot |> + right_join(adsl, by = "USUBJID") |> + distinct(USUBJID, .keep_all = TRUE) + +# Pre-process ADAE + +adae_base <- adae_jnj |> + filter(!!ae_filter) + +adae_nabstat <- adae_base |> + filter(NABSTAT %in% c("POSITIVE", "NEGATIVE")) |> + distinct(USUBJID, NABSTAT) + +adae_sev <- adae_base |> + filter(toupper(AESEV) == "SEVERE") |> + mutate(SEVFL = "Y") |> + distinct(USUBJID, SEVFL) + +adae_tox <- adae_base |> + group_by(USUBJID) |> + summarise( + TOXFL = if_else(any(AETOXGRN >= 3, na.rm = TRUE), "Y", NA_character_), + .groups = "drop" + ) |> + filter(TOXFL == "Y") + +adae_ser <- adae_base |> + filter(AESER == "Y") |> + distinct(USUBJID, AESER) + +adae_dct <- adae_base |> + filter(TRDISCFL == "Y") |> + distinct(USUBJID, TRDISCFL) + +adae_dosct <- adae_base |> + group_by(USUBJID) |> + summarise( + NDOSDT = n_distinct(!!sym(aedosdtvar), na.rm = TRUE), + .groups = "drop" + ) + +# Pre-process ADEXSUM + +adexsum_base <- adexsum_jnj |> + filter(!!adexsum_filter, PARAMCD == adexsumprmcd) |> + select(USUBJID, AVAL) |> + rename(TINFUS = AVAL) + +# Join all data together + +join_df <- list(adae_nabstat, adae_sev, adae_tox, adae_ser, adae_dct, adae_dosct, adexsum_base) + +adishum_f1 <- purrr::reduce( + join_df, + ~ left_join(.x, .y, by = "USUBJID"), + .init = adishum +) + +adishum_f <- adishum_f1 |> + left_join( + adae_base |> + distinct(USUBJID) |> + mutate(AEFL = "Y"), + by = "USUBJID" + ) + +sg_var <- if (sev_grade_fl == "AESEV") { + "SEVFL" +} else if (sev_grade_fl == "AETOXGRN") { + "TOXFL" +} + +adishum_final <- adishum_f |> + mutate( + P1FL = ifelse(NABSTAT == "POSITIVE" & AEFL == "Y", "Y", NA), + P2FL = ifelse(NABSTAT == "POSITIVE" & !!sym(sg_var) == "Y", "Y", NA), + P3FL = ifelse(NABSTAT == "POSITIVE" & AESER == "Y", "Y", NA), + P4FL = ifelse(NABSTAT == "POSITIVE" & TRDISCFL == "Y", "Y", NA), + PNDOSDT = ifelse(NABSTAT == "POSITIVE", NDOSDT, NA), + PTINFUS = ifelse(NABSTAT == "POSITIVE", TINFUS, NA), + N1FL = ifelse(NABSTAT == "NEGATIVE" & AEFL == "Y", "Y", NA), + N2FL = ifelse(NABSTAT == "NEGATIVE" & !!sym(sg_var) == "Y", "Y", NA), + N3FL = ifelse(NABSTAT == "NEGATIVE" & AESER == "Y", "Y", NA), + N4FL = ifelse(NABSTAT == "NEGATIVE" & TRDISCFL == "Y", "Y", NA), + NNDOSDT = ifelse(NABSTAT == "NEGATIVE", NDOSDT, NA), + NTINFUS = ifelse(NABSTAT == "NEGATIVE", TINFUS, NA) + ) + + +################################################################################ +# Create Layout: +################################################################################ + +lyt <- basic_table() |> + split_cols_by( + "colspan_trt", + split_fun = drop_split_levels + ) + +if (combined_colspan_trt) { + lyt <- lyt |> + split_cols_by( + var = trtvar, + show_colcounts = TRUE, + colcount_format = "N=xx", + split_fun = add_overall_level("Combined", first = FALSE) + ) +} else { + lyt <- lyt |> + split_cols_by( + var = trtvar, + show_colcounts = TRUE, + colcount_format = "N=xx" + ) +} + +lyt <- lyt |> + analyze( + "ADATRE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = paste("Subjects positive for treatment-emergent", agt_antiagt_lbl, "at any time~[super a]"), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "NAB", + indent_mod = 1L, + afun = a_freq_j, + show_labels = "hidden", + section_div = " ", + extra_args = list( + label = "Subjects evaluable for neutralizing antibodies ~[super b]", + val = "Y", + .stats = c("count_unique") + ) + ) |> + split_rows_by("NABPOS", split_fun = keep_split_levels("Y"), child_labels = "hidden") |> + analyze( + "NABPOS", + indent_mod = 2L, + afun = a_freq_j, + table_names = "nabp", + show_labels = "hidden", + extra_args = list( + label = paste("Subjects positive for neutralizing", agt_antiagt_lbl, "~[super c,e]"), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "P1FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with infusion-related reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABPOS" + ) + ) |> + analyze( + "P2FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = paste("Subjects with", sev_grade_lbl, "infusion-related reaction, n (%)"), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABPOS" + ) + ) |> + analyze( + "P3FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with serious infusion-related reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABPOS" + ) + ) |> + analyze( + "P4FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with infusion-related reaction leading to treatment discontinuation, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABPOS" + ) + ) |> + analyze( + "PTINFUS", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 3L, + extra_args = list( + .stats = "sum_unique", + .labels = c(sum_unique = paste("Total number of", agent_name, "infusions")), + id_var = "USUBJID" + ) + ) |> + analyze( + "PNDOSDT", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 4L, + section_div = " ", + extra_args = list( + .stats = "ratio_unique", + denom_by = "PTINFUS", + .labels = c(ratio_unique = "Infusions with infusion-related reactions~[super f], n (%)"), + id_var = "USUBJID" + ) + ) |> + split_rows_by("NABNEG", nested = FALSE, split_fun = keep_split_levels("Y"), child_labels = "hidden") |> + analyze( + "NABNEG", + table_names = "nabn", + indent_mod = 2L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = paste("Subjects negative for neutralizing", agt_antiagt_lbl, "~[super d,e]"), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "N1FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with infusion-related reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABNEG" + ) + ) |> + analyze( + "N2FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = paste("Subjects with", sev_grade_lbl, "infusion-related reaction, n (%)"), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABNEG" + ) + ) |> + analyze( + "N3FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with serious infusion-related reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABNEG" + ) + ) |> + analyze( + "N4FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with infusion-related reaction leading to treatment discontinuation, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABNEG" + ) + ) |> + analyze( + "NTINFUS", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 3L, + extra_args = list( + .stats = "sum_unique", + .labels = c(sum_unique = paste("Total number of", agent_name, "infusions")), + id_var = "USUBJID" + ) + ) |> + analyze( + "NNDOSDT", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 4L, + extra_args = list( + .stats = "ratio_unique", + denom_by = "NTINFUS", + .labels = c(ratio_unique = "Infusions with infusion-related reactions~[super f], n (%)"), + id_var = "USUBJID" + ) + ) + +################################################################################ +# Create Table Shell: +################################################################################ + +result <- build_table(lyt, adishum_final, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tirnab03.R b/tests/testthat/source_code/tirnab03.R new file mode 100644 index 00000000..fbe94c97 --- /dev/null +++ b/tests/testthat/source_code/tirnab03.R @@ -0,0 +1,433 @@ +library(envsetup) +library(tern) +library(dplyr) +library(tidyr) +library(rtables) +library(junco) +library(forcats) +library(tidyselect) +library(purrr) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TIRNAB03" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "SAFFL" +trtvar <- "TRT01A" +combined_colspan_trt <- TRUE + +################################################################################ +# ADISHUM parameters/ filter criteria: +################################################################################ +parqual <- "XANOMELINE" +addon_filter <- expr(.data[[trtvar]] != "Placebo") # To be used with ADISHUM. +# addon_filter <- expr(TRUE) # If no filter required +agent_name <- "active study agent" +agt_antiagt_lbl <- "antibodies to active study agent" +sev_grade_fl <- "AESEV" +# sev_grade_fl <- "AETOXGRN" +sev_grade_lbl <- "severe" +# sev_grade_lbl <- ">=grade 3" + +ae_filter <- expr(SAFFL == "Y" & AESCAT == "Injection site reaction") +aedosdtvar <- "DOSEDT" + +adexsum_filter <- expr(SAFFL == "Y") +adexsumprmcd <- "TNUMDOS" + +################################################################################ +# Process data: +################################################################################ + +# Pre-process ADSL + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y", .data[[trtvar]] != "Placebo") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ), + {{ trtvar }} := fct_drop(.data[[trtvar]]) + ) |> + mutate(colspan_trt = "Active Study Agent") |> + select(USUBJID, all_of(trtvar), all_of(popfl), colspan_trt) + +# Pre-process ADISHUM + +adishum <- adishum_jnj |> + filter(.data[[popfl]] == "Y", PARQUAL == parqual, !!addon_filter) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ), + {{ trtvar }} := fct_drop(.data[[trtvar]]) + ) |> + select( + USUBJID, + all_of(trtvar), + all_of(popfl), + PARAMCD, + AVALC + ) + +adishum_pivot <- adishum |> + filter(PARAMCD %in% c("ADATRE", "NABPOS", "NABNEG")) |> + pivot_wider( + id_cols = c(USUBJID), + names_from = PARAMCD, + values_from = AVALC + ) |> + mutate(NAB = ifelse(NABPOS == "Y" | NABNEG == "Y", "Y", NA)) + +adishum <- adishum_pivot |> + right_join(adsl, by = "USUBJID") |> + distinct(USUBJID, .keep_all = TRUE) + + +# Pre-process ADAE + +adae_base <- adae_jnj |> + filter(!!ae_filter) + +adae_nabstat <- adae_base |> + filter(NABSTAT %in% c("POSITIVE", "NEGATIVE")) |> + distinct(USUBJID, NABSTAT) + +adae_sev <- adae_base |> + filter(toupper(AESEV) == "SEVERE") |> + mutate(SEVFL = "Y") |> + distinct(USUBJID, SEVFL) + +adae_tox <- adae_base |> + group_by(USUBJID) |> + summarise( + TOXFL = if_else(any(AETOXGRN >= 3, na.rm = TRUE), "Y", NA_character_), + .groups = "drop" + ) |> + filter(TOXFL == "Y") + +adae_ser <- adae_base |> + filter(AESER == "Y") |> + distinct(USUBJID, AESER) + +adae_dct <- adae_base |> + filter(TRDISCFL == "Y") |> + distinct(USUBJID, TRDISCFL) + +adae_dosct <- adae_base |> + group_by(USUBJID) |> + summarise( + NDOSDT = n_distinct(!!sym(aedosdtvar), na.rm = TRUE), + .groups = "drop" + ) + +# Pre-process ADEXSUM + +adexsum_base <- adexsum_jnj |> + filter(!!adexsum_filter, PARAMCD == adexsumprmcd) |> + select(USUBJID, AVAL) |> + rename(TINFUS = AVAL) + +# Join all data together + +join_df <- list(adae_nabstat, adae_sev, adae_tox, adae_ser, adae_dct, adae_dosct, adexsum_base) + +adishum_f1 <- purrr::reduce( + join_df, + ~ left_join(.x, .y, by = "USUBJID"), + .init = adishum +) + +adishum_f <- adishum_f1 |> + left_join( + adae_base |> + distinct(USUBJID) |> + mutate(AEFL = "Y"), + by = "USUBJID" + ) + +sg_var <- if (sev_grade_fl == "AESEV") { + "SEVFL" +} else if (sev_grade_fl == "AETOXGRN") { + "TOXFL" +} + +adishum_final <- adishum_f |> + mutate( + P1FL = ifelse(NABSTAT == "POSITIVE" & AEFL == "Y", "Y", NA), + P2FL = ifelse(NABSTAT == "POSITIVE" & !!sym(sg_var) == "Y", "Y", NA), + P3FL = ifelse(NABSTAT == "POSITIVE" & AESER == "Y", "Y", NA), + P4FL = ifelse(NABSTAT == "POSITIVE" & TRDISCFL == "Y", "Y", NA), + PNDOSDT = ifelse(NABSTAT == "POSITIVE", NDOSDT, NA), + PTINFUS = ifelse(NABSTAT == "POSITIVE", TINFUS, NA), + N1FL = ifelse(NABSTAT == "NEGATIVE" & AEFL == "Y", "Y", NA), + N2FL = ifelse(NABSTAT == "NEGATIVE" & !!sym(sg_var) == "Y", "Y", NA), + N3FL = ifelse(NABSTAT == "NEGATIVE" & AESER == "Y", "Y", NA), + N4FL = ifelse(NABSTAT == "NEGATIVE" & TRDISCFL == "Y", "Y", NA), + NNDOSDT = ifelse(NABSTAT == "NEGATIVE", NDOSDT, NA), + NTINFUS = ifelse(NABSTAT == "NEGATIVE", TINFUS, NA) + ) + + +################################################################################ +# Create Layout: +################################################################################ + +lyt <- basic_table() |> + split_cols_by( + "colspan_trt", + split_fun = drop_split_levels + ) + +if (combined_colspan_trt) { + lyt <- lyt |> + split_cols_by( + var = trtvar, + show_colcounts = TRUE, + colcount_format = "N=xx", + split_fun = add_overall_level("Combined", first = FALSE) + ) +} else { + lyt <- lyt |> + split_cols_by( + var = trtvar, + show_colcounts = TRUE, + colcount_format = "N=xx" + ) +} + +lyt <- lyt |> + analyze( + "ADATRE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = paste("Subjects positive for treatment-emergent", agt_antiagt_lbl, "at any time~[super a]"), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "NAB", + indent_mod = 1L, + afun = a_freq_j, + show_labels = "hidden", + section_div = " ", + extra_args = list( + label = "Subjects evaluable for neutralizing antibodies ~[super b]", + val = "Y", + .stats = c("count_unique") + ) + ) |> + split_rows_by("NABPOS", split_fun = keep_split_levels("Y"), child_labels = "hidden") |> + analyze( + "NABPOS", + indent_mod = 2L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = paste("Subjects positive for neutralizing", agt_antiagt_lbl, "~[super c,e]"), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "P1FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with injection site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABPOS" + ) + ) |> + analyze( + "P2FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = paste("Subjects with", sev_grade_lbl, "injection site reaction, n (%)"), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABPOS" + ) + ) |> + analyze( + "P3FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with serious injection site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABPOS" + ) + ) |> + analyze( + "P4FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with injection site reaction leading to treatment discontinuation, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABPOS" + ) + ) |> + analyze( + "PTINFUS", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 3L, + extra_args = list( + .stats = "sum_unique", + .labels = c(sum_unique = paste("Total number of", agent_name, "injections")), + id_var = "USUBJID" + ) + ) |> + analyze( + "PNDOSDT", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 4L, + section_div = " ", + extra_args = list( + .stats = "ratio_unique", + denom_by = "PTINFUS", + .labels = c(ratio_unique = "Injections with injection site reactions~[super f], n (%)"), + id_var = "USUBJID" + ) + ) |> + split_rows_by("NABNEG", nested = FALSE, split_fun = keep_split_levels("Y"), child_labels = "hidden") |> + analyze( + "NABNEG", + indent_mod = 2L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = paste("Subjects negative for neutralizing", agt_antiagt_lbl, "~[super d,e]"), + val = "Y", + .stats = c("count_unique") + ) + ) |> + analyze( + "N1FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with injection site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABNEG" + ) + ) |> + analyze( + "N2FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = paste("Subjects with", sev_grade_lbl, "injection site reaction, n (%)"), + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABNEG" + ) + ) |> + analyze( + "N3FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with serious injection site reaction, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABNEG" + ) + ) |> + analyze( + "N4FL", + indent_mod = 3L, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + label = "Subjects with injection site reaction leading to treatment discontinuation, n (%)", + val = "Y", + .stats = c("count_unique_fraction"), + denom = "n_parentdf", + denom_by = "NABNEG" + ) + ) |> + analyze( + "NTINFUS", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 3L, + extra_args = list( + .stats = "sum_unique", + .labels = c(sum_unique = paste("Total number of", agent_name, "injections")), + id_var = "USUBJID" + ) + ) |> + analyze( + "NNDOSDT", + afun = a_sum_ratio_j, + show_labels = "hidden", + indent_mod = 4L, + extra_args = list( + .stats = "ratio_unique", + denom_by = "NTINFUS", + .labels = c(ratio_unique = "Injections with injection site reactions~[super f], n (%)"), + id_var = "USUBJID" + ) + ) + +################################################################################ +# Create Table Shell: +################################################################################ + +result <- build_table(lyt, adishum_final, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tpk01a.R b/tests/testthat/source_code/tpk01a.R index d26ab487..a7bd5459 100644 --- a/tests/testthat/source_code/tpk01a.R +++ b/tests/testthat/source_code/tpk01a.R @@ -1,29 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tpk01a -## R version: 4.4.2 -## Short Description: Program to create tpk01a: -## [Matrix] [Active Study Agent/Analyte] -## Concentrations ([units]) Over Time; -## Pharmacokinetics Analysis Set (Study jjcs - core) -## Author: Johnson & Johnson Innovative Medicine -## Date: 12AUG2025 -## Input: adpc.rds, adsl.rds -## Output: tpk01a.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(dplyr) library(forcats) @@ -37,58 +11,75 @@ library(junco) tblid <- "TPK01a" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) popfl <- "PKFL" trtvar <- "TRT01A" +paramcd <- "XAN" + # Flags indicating whether to include certain statistics in the table add_geometric_mean <- TRUE add_cv <- TRUE add_interquartile_range <- TRUE +# flag to indicate if ATPT is present in the study +# if TRUE, time point is concatenation of AVISIT and ATPT +# if FALSE, time point is AVISIT only +use_atpt <- TRUE + ################################################################################ # Process data: ################################################################################ adsl <- adsl_jnj |> filter(.data[[popfl]] == "Y") |> - select(USUBJID, all_of(trtvar), PKFL) |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> # Drop the control group filter(.data[[trtvar]] != "Placebo") |> mutate({{ trtvar }} := fct_drop(.data[[trtvar]])) |> - mutate(colspan_trt = "Active Study Agent") + mutate(colspan_trt = "Active Study Agent") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ) + ) + adpc <- adpc_jnj |> - filter(PARAMCD == "XAN") |> - select(USUBJID, all_of(trtvar), AVISIT, ATPT, AVAL) |> - inner_join(adsl) |> - # Concatenate and reorder time points - mutate(AVISIT_ATPT = factor(paste(AVISIT, ATPT, sep = " - "), levels = c( - "Day 1 - Pre-dose", - "Day 1 - 5 Min Post-dose", - "Day 1 - 30 Min Post-dose", - "Day 1 - 1h Post-dose", - "Day 1 - 1.5h Post-dose", - "Day 1 - 2h Post-dose", - "Day 1 - 4h Post-dose", - "Day 1 - 0-6h Post-dose", - "Day 1 - 6h Post-dose", - "Day 1 - 8h Post-dose", - "Day 1 - 6-12h Post-dose", - "Day 1 - 12h Post-dose", - "Day 1 - 16h Post-dose", - "Day 1 - 12-24h Post-dose", - "Day 2 - 24h Post-dose", - "Day 2 - Pre-dose", - "Day 2 - 36h Post-dose", - "Day 2 - 24-48h Post-dose", - "Day 3 - 48h Post-dose", - "Day 3 - Pre-dose" - ))) + filter(PARAMCD == paramcd) |> # If not required this filter can be removed + select(STUDYID, USUBJID, AVISIT, AVISITN, any_of(c("ATPT", "ATPTN")), AVAL) |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) + +# derive selvisit from data, ordered by AVISITN then ATPTN +selvisit <- if (use_atpt) { + adpc |> + arrange(AVISITN, ATPTN) |> + distinct(AVISIT, ATPT) |> + mutate(AVISIT_ATPT = paste(AVISIT, ATPT, sep = ", ")) |> + pull(AVISIT_ATPT) +} else { + adpc |> + arrange(AVISITN) |> + distinct(AVISIT) |> + pull(AVISIT) +} + + +adpc <- adpc |> + mutate( + AVISIT_ATPT = factor( + if (use_atpt) paste(AVISIT, ATPT, sep = ", ") else as.character(AVISIT), + levels = selvisit + ) + ) ################################################################################ # Define layout and build table: @@ -135,12 +126,16 @@ lyt <- basic_table() |> ), .formats = c( n = jjcsformat_xx("xx"), - mean_sd = jjcsformat_xx("xx.xx (xx.xx)"), - median = jjcsformat_xx("xx.xx"), - geom_mean = jjcsformat_xx("xx.xx"), - range = jjcsformat_xx("xx.xx, xx.xx"), + mean_sd = format_sigfig_j(3, format = "xx (xx)"), + median = format_sigfig_j(3, format = "xx"), + geom_mean = format_sigfig_j(3, format = "xx"), + range = format_sigfig_j(3, format = "(xx, xx)"), cv = jjcsformat_xx("xx.x"), - quantiles = jjcsformat_xx("xx.xx, xx.xx") + quantiles = format_sigfig_j(3, format = "(xx, xx)") + ), + control = control_analyze_vars( + quantiles = c(0.25, 0.75), + quantile_type = 2 ), .indent_mods = c( n = 0, @@ -154,18 +149,19 @@ lyt <- basic_table() |> ) ) -result <- build_table(lyt, df = adpc, alt_counts_df = adsl) +result <- build_table(lyt, df = adpc, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table: ################################################################################ -colwidth <- c(44, 23, 23, 23) + +colwidth <- c(41, 29, 29, 29) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tpk01b.R b/tests/testthat/source_code/tpk01b.R index 2c001ad8..baf13e69 100644 --- a/tests/testthat/source_code/tpk01b.R +++ b/tests/testthat/source_code/tpk01b.R @@ -1,31 +1,6 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tpk01b -## R version: 4.4.2 -## Short Description: Program to create tpk01b: -## [Matrix] [Active Study Agent/Analyte] -## Concentrations ([units]) Over Time; -## Pharmacokinetics Analysis Set (Study jjcs - core) -## Author: Johnson & Johnson Innovative Medicine -## Date: 19AUG2025 -## Input: adpc.rds, adsl.rds -## Output: tpk01b.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(dplyr) +library(forcats) library(rtables) library(tern) library(junco) @@ -36,123 +11,132 @@ library(junco) tblid <- "TPK01b" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) popfl <- "PKFL" trtvar <- "TRT01A" +add_geometric_mean <- TRUE +add_cv <- TRUE +paramcd <- "XAN" -trt_grps <- c("Xanomeline High Dose", "Xanomeline Low Dose") - -for (i in seq_along(trt_grps)) { - trt_grp <- trt_grps[i] - path <- paste0(fileid, "part", i, "of", length(trt_grps)) - - ############################################################################## - # Process data: - ############################################################################## - - adsl <- adsl_jnj |> - filter(.data[[popfl]] == "Y") |> - select(USUBJID, all_of(trtvar), PKFL) |> - filter(.data[[trtvar]] == trt_grp) |> - mutate(colspan = "Observed") - - adpc <- adpc_jnj |> - filter(PARAMCD == "XAN") |> - select(USUBJID, all_of(trtvar), AVISIT, ATPT, AVAL) |> - filter(.data[[trtvar]] == trt_grp) |> - inner_join(adsl) |> - # Concatenate and reorder time points - mutate(AVISIT_ATPT = factor(paste(AVISIT, ATPT, sep = " - "), levels = c( - "Day 1 - Pre-dose", - "Day 1 - 5 Min Post-dose", - "Day 1 - 30 Min Post-dose", - "Day 1 - 1h Post-dose", - "Day 1 - 1.5h Post-dose", - "Day 1 - 2h Post-dose", - "Day 1 - 4h Post-dose", - "Day 1 - 0-6h Post-dose", - "Day 1 - 6h Post-dose", - "Day 1 - 8h Post-dose", - "Day 1 - 6-12h Post-dose", - "Day 1 - 12h Post-dose", - "Day 1 - 16h Post-dose", - "Day 1 - 12-24h Post-dose", - "Day 2 - 24h Post-dose", - "Day 2 - Pre-dose", - "Day 2 - 36h Post-dose", - "Day 2 - 24-48h Post-dose", - "Day 3 - 48h Post-dose", - "Day 3 - Pre-dose" - ))) - - ############################################################################## - # Define layout and build table: - ############################################################################## - - lyt <- basic_table() |> - split_cols_by( - var = trtvar, - show_colcounts = TRUE, - colcount_format = "N=xx", - split_fun = drop_split_levels - ) |> - split_cols_by("colspan") |> - split_rows_by( - var = "AVISIT_ATPT", - split_label = "Time Point", - label_pos = "topleft", - child_labels = "hidden" - ) |> - analyze_vars_in_cols( - vars = "AVAL", - .stats = c( - "n", - "mean", - "sd", - "median", - "min", - "max", - "cv", - "geom_mean" - ), - .labels = c( - n = "N", - mean = "Mean", - sd = "SD", - median = "Med", - min = "Min", - max = "Max", - cv = "% CV", - geom_mean = "Geometric Mean" - ), - .formats = c( - n = jjcsformat_xx("xx"), - mean = jjcsformat_xx("xx.xx"), - sd = jjcsformat_xx("xx.xx"), - median = jjcsformat_xx("xx.xx"), - min = jjcsformat_xx("xx.xx"), - max = jjcsformat_xx("xx.xx"), - cv = jjcsformat_xx("xx.x"), - geom_mean = jjcsformat_xx("xx.xx") - ) - ) - result <- build_table(lyt, df = adpc, alt_counts_df = adsl) +# flag to indicate if ATPT is present in the study +# if TRUE, time point is concatenation of AVISIT and ATPT +# if FALSE, time point is AVISIT only +use_atpt <- TRUE - ############################################################################## - # Add titles and footnotes: - ############################################################################## - result <- set_titles(result, titles) +trt_grps <- c("Xanomeline Low Dose", "Xanomeline High Dose") - colwidth <- c(44, 11, 16, 14, 16, 16, 16, 16, 16) - ############################################################################## - # Convert to tbl file and output table: - ############################################################################## +################################################################################ +# Process data: +################################################################################ - tt_to_tlgrtf(colwidths = colwidth, result, file = path, orientation = "landscape") +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + filter(.data[[trtvar]] == trt_grps) |> + select(STUDYID, USUBJID, all_of(trtvar), PKFL) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = trt_grps + ) + ) + +adpc <- adpc_jnj |> + filter(PARAMCD == paramcd) |> # If not required this filter can be removed + select(STUDYID, USUBJID, AVISIT, AVISITN, any_of(c("ATPT", "ATPTN")), AVAL) |> + inner_join(adsl, by = c("USUBJID", "STUDYID")) + +# derive selvisit from data, ordered by AVISITN then ATPTN +selvisit <- if (use_atpt) { + adpc |> + arrange(AVISITN, ATPTN) |> + distinct(AVISIT, ATPT) |> + mutate(AVISIT_ATPT = paste(AVISIT, ATPT, sep = ", ")) |> + pull(AVISIT_ATPT) +} else { + adpc |> + arrange(AVISITN) |> + distinct(AVISIT) |> + pull(AVISIT) } + +adpc <- adpc |> + mutate( + AVISIT_ATPT = factor( + if (use_atpt) paste(AVISIT, ATPT, sep = ", ") else as.character(AVISIT), + levels = selvisit + ) + ) + +################################################################################ +# Define layout and build table: +################################################################################ + +lyt <- basic_table() |> + split_cols_by( + var = trtvar, + show_colcounts = TRUE, + colcount_format = "N=xx", + split_fun = drop_split_levels + ) |> + split_rows_by( + var = "AVISIT_ATPT", + split_label = "Time Point", + label_pos = "topleft", + child_labels = "hidden" + ) |> + analyze_vars_in_cols( + vars = "AVAL", + .stats = c( + "n", + "mean", + "sd", + "median", + "min", + "max", + if (add_cv) "cv" else NULL, + if (add_geometric_mean) "geom_mean" else NULL + ), + .labels = c( + n = "N", + mean = "Mean", + sd = "SD", + median = "Med", + min = "Min", + max = "Max", + cv = "% CV", + geom_mean = "Geometric Mean" + ), + .formats = c( + n = jjcsformat_xx("xx"), + mean = format_sigfig_j(3, format = "xx"), + sd = format_sigfig_j(3, format = "xx"), + median = format_sigfig_j(3, format = "xx"), + min = format_sigfig_j(3, format = "xx"), + max = format_sigfig_j(3, format = "xx"), + cv = jjcsformat_xx("xx.x"), + geom_mean = format_sigfig_j(3, format = "xx") + ) + ) + +result <- build_table(lyt, df = adpc, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(42, 7, 16, 16, 16, 16, 16, 12, 16, 7, 16, 16, 16, 16, 16, 12, 16) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape", combined_rtf = TRUE, nosplitin = list(cols = trtvar)) diff --git a/tests/testthat/source_code/tpk02.R b/tests/testthat/source_code/tpk02.R index c63cc534..ca5fe812 100644 --- a/tests/testthat/source_code/tpk02.R +++ b/tests/testthat/source_code/tpk02.R @@ -1,32 +1,6 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tpk02 -## R version: 4.4.2 -## Short Description: Program to create tpk02: -## [Matrix] [Active Study Agent/Analyte] -## Concentrations ([units]) Over Time by -## [Body Weight] [Quartiles]; Pharmacokinetics -## Analysis Set (Study jjcs - core) -## Author: Johnson & Johnson Innovative Medicine -## Date: 20AUG2025 -## Input: adpc.rds, adsl.rds -## Output: tpk02.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(dplyr) +library(forcats) library(rtables) library(tern) library(junco) @@ -37,139 +11,162 @@ library(junco) tblid <- "TPK02" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) popfl <- "PKFL" trtvar <- "TRT01A" +paramcd <- "XAN" + +# Subset variable: "WGTGR1" (body weight quartiles) or "BMIGR1" (BMI quartiles) +# or study-specific category variable (refer to SAP) +subgrpvar <- "WGTGR1" +subgrp_label <- "Body Weight (kg)" # Flags indicating whether to include certain statistics in the table add_geometric_mean <- TRUE add_cv <- TRUE add_interquartile_range <- TRUE -trt_grps <- c("Xanomeline High Dose", "Xanomeline Low Dose") - -for (i in seq_along(trt_grps)) { - trt_grp <- trt_grps[i] - path <- paste0(fileid, "part", i, "of", length(trt_grps)) - - ############################################################################## - # Process data: - ############################################################################## - - adsl <- adsl_jnj |> - filter(.data[[popfl]] == "Y") |> - filter(.data[[trtvar]] == trt_grp) |> - select(USUBJID, all_of(trtvar), WGTGR1, PKFL) |> - mutate(colspan = "[Body Weight (kg)] [Quartiles]") - - adpc <- adpc_jnj |> - filter(PARAMCD == "XAN") |> - filter(.data[[trtvar]] == trt_grp) |> - select(USUBJID, all_of(trtvar), AVISIT, ATPT, AVAL) |> - inner_join(adsl) |> - # Concatenate and reorder time points - mutate(AVISIT_ATPT = factor(paste(AVISIT, ATPT, sep = " - "), levels = c( - "Day 1 - Pre-dose", - "Day 1 - 5 Min Post-dose", - "Day 1 - 30 Min Post-dose", - "Day 1 - 1h Post-dose", - "Day 1 - 1.5h Post-dose", - "Day 1 - 2h Post-dose", - "Day 1 - 4h Post-dose", - "Day 1 - 0-6h Post-dose", - "Day 1 - 6h Post-dose", - "Day 1 - 8h Post-dose", - "Day 1 - 6-12h Post-dose", - "Day 1 - 12h Post-dose", - "Day 1 - 16h Post-dose", - "Day 1 - 12-24h Post-dose", - "Day 2 - 24h Post-dose", - "Day 2 - Pre-dose", - "Day 2 - 36h Post-dose", - "Day 2 - 24-48h Post-dose", - "Day 3 - 48h Post-dose", - "Day 3 - Pre-dose" - ))) - - ############################################################################## - # Define layout and build table: - ############################################################################## - - lyt <- basic_table() |> - split_cols_by( - var = trtvar, - show_colcounts = TRUE, - colcount_format = "N=xx", - split_fun = drop_split_levels - ) |> - split_cols_by("colspan") |> - split_cols_by("WGTGR1") |> - split_rows_by( - var = "AVISIT_ATPT", - split_label = "Time Point", - label_pos = "topleft", - section_div = " " - ) |> - analyze( - vars = "AVAL", - afun = a_summary, - extra_args = list( - .stats = c( - "n", - "mean_sd", - "median", - if (add_geometric_mean) "geom_mean" else NULL, - "range", - if (add_cv) "cv" else NULL, - if (add_interquartile_range) "quantiles" else NULL - ), - .labels = c( - n = "N", - mean_sd = "Mean (SD)", - median = "Median", - geom_mean = "Geometric mean", - range = "Min, max", - cv = "CV (%)", - quantiles = "Interquartile range" - ), - .formats = c( - n = jjcsformat_xx("xx"), - mean_sd = jjcsformat_xx("xx.xx (xx.xx)"), - median = jjcsformat_xx("xx.xx"), - geom_mean = jjcsformat_xx("xx.xx"), - range = jjcsformat_xx("xx.xx, xx.xx"), - cv = jjcsformat_xx("xx.x"), - quantiles = jjcsformat_xx("xx.xx, xx.xx") - ), - .indent_mods = c( - n = 0, - mean_sd = 1, - median = 1, - geom_mean = 1, - range = 1, - cv = 1, - quantiles = 1 - ) + +# flag to indicate if ATPT is present in the study +# if TRUE, time point is concatenation of AVISIT and ATPT +# if FALSE, time point is AVISIT only +use_atpt <- TRUE + +trt_grps <- c("Xanomeline Low Dose", "Xanomeline High Dose") + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + filter(.data[[trtvar]] == trt_grps) |> + select(STUDYID, USUBJID, all_of(c(trtvar, popfl, subgrpvar))) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = trt_grps + ), + colspan = subgrp_label + ) + +adpc <- adpc_jnj |> + filter(PARAMCD == paramcd) |> # If not required this filter can be removed + select(STUDYID, USUBJID, AVISIT, AVISITN, any_of(c("ATPT", "ATPTN")), AVAL) |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) + +# derive selvisit from data, ordered by AVISITN then ATPTN +selvisit <- if (use_atpt) { + adpc |> + arrange(AVISITN, ATPTN) |> + distinct(AVISIT, ATPT) |> + mutate(AVISIT_ATPT = paste(AVISIT, ATPT, sep = ", ")) |> + pull(AVISIT_ATPT) +} else { + adpc |> + arrange(AVISITN) |> + distinct(AVISIT) |> + pull(AVISIT) +} + +adpc <- adpc |> + mutate( + AVISIT_ATPT := factor( + if (use_atpt) paste(AVISIT, ATPT, sep = ", ") else as.character(AVISIT), + levels = selvisit + ) + ) + +################################################################################ +# Define layout and build table: +################################################################################ + +lyt <- basic_table() |> + split_cols_by( + var = trtvar, + show_colcounts = TRUE, + colcount_format = "N=xx", + split_fun = drop_split_levels + ) |> + split_cols_by( + var = "colspan", + split_fun = drop_split_levels + ) |> + split_cols_by( + var = subgrpvar, + split_fun = drop_split_levels + ) |> + split_rows_by( + var = "AVISIT_ATPT", + split_label = "Time Point", + label_pos = "topleft", + section_div = " ", + split_fun = drop_split_levels + ) |> + analyze( + vars = "AVAL", + afun = a_summary, + extra_args = list( + .stats = c( + "n", + "mean_sd", + "median", + if (add_geometric_mean) "geom_mean" else NULL, + "range", + if (add_cv) "cv" else NULL, + if (add_interquartile_range) "quantiles" else NULL + ), + .labels = c( + n = "N", + mean_sd = "Mean (SD)", + median = "Median", + geom_mean = "Geometric mean", + range = "Min, max", + cv = "CV (%)", + quantiles = "Interquartile range" + ), + .formats = c( + n = jjcsformat_xx("xx"), + mean_sd = format_sigfig_j(3, format = "xx (xx)"), + median = format_sigfig_j(3, format = "xx"), + geom_mean = format_sigfig_j(3, format = "xx"), + range = format_sigfig_j(3, format = "(xx, xx)"), + cv = jjcsformat_xx("xx.x"), + quantiles = format_sigfig_j(3, format = "(xx, xx)") + ), + control = control_analyze_vars( + quantiles = c(0.25, 0.75), + quantile_type = 2 + ), + .indent_mods = c( + n = 0L, + mean_sd = 1L, + median = 1L, + geom_mean = 1L, + range = 1L, + cv = 1L, + quantiles = 1L ) ) + ) - result <- build_table(lyt, df = adpc, alt_counts_df = adsl) +result <- build_table(lyt, df = adpc, alt_counts_df = adsl, round_type = "sas") - ############################################################################## - # Add titles and footnotes: - ############################################################################## +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) - result <- set_titles(result, titles) +################################################################################ +# Convert to tbl file and output table: +################################################################################ - colwidth <- c(44, 23, 23, 23, 23) - ############################################################################## - # Convert to tbl file and output table: - ############################################################################## +colwidth <- c(41, 31, 29, 31, 29, 31, 31, 29, 29) - tt_to_tlgrtf(colwidths = colwidth, result, file = path, orientation = "portrait") -} +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait", combined_rtf = TRUE, nosplitin = list(cols = trtvar)) diff --git a/tests/testthat/source_code/tpk03.R b/tests/testthat/source_code/tpk03.R index 940bc06d..3a058260 100644 --- a/tests/testthat/source_code/tpk03.R +++ b/tests/testthat/source_code/tpk03.R @@ -1,31 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tpk03 -## R version: 4.4.2 -## Short Description: Program to create tpk03: -## Subjects With [Matrix] -## [Active Study Agent/Analyte] Concentrations Below -## the Lowest Quantification Level ([LLOQ/LLOQxMRD -## and units]) Over Time; Pharmacokinetics Analysis -## Set (Study jjcs - core) -## Author: Johnson & Johnson Innovative Medicine -## Date: 22AUG2025 -## Input: adpc.rds, adsl.rds -## Output: tpk03.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(dplyr) library(forcats) @@ -39,13 +11,24 @@ library(junco) tblid <- "TPK03" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) popfl <- "PKFL" trtvar <- "TRT01A" +paramcd <- "XAN" + +# flag to indicate if ATPT is present in the study +# if TRUE, time point is concatenation of AVISIT and ATPT +# if FALSE, time point is AVISIT only +use_atpt <- TRUE + +# lloq_label: the threshold term to display in the label +# e.g. "LLOQxMRD" or "LLOQ" +lloq_label <- "LLOQxMRD" + ################################################################################ # Process data: @@ -53,39 +36,53 @@ trtvar <- "TRT01A" adsl <- adsl_jnj |> filter(.data[[popfl]] == "Y") |> - select(USUBJID, all_of(trtvar), PKFL) |> + select(STUDYID, USUBJID, all_of(c(trtvar, popfl))) |> # Drop the control group filter(.data[[trtvar]] != "Placebo") |> mutate({{ trtvar }} := fct_drop(.data[[trtvar]])) |> - mutate(colspan_trt = "Active Study Agent") + mutate(colspan_trt = "Active Study Agent") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ) + ) + + +# IF ATPT not present user can remove it from select statement adpc <- adpc_jnj |> - filter(PARAMCD == "XAN") |> - select(USUBJID, all_of(trtvar), AVISIT, ATPT, CRIT1FL) |> - inner_join(adsl) |> - # Concatenate and reorder time points - mutate(AVISIT_ATPT = factor(paste(AVISIT, ATPT, sep = " - "), levels = c( - "Day 1 - Pre-dose", - "Day 1 - 5 Min Post-dose", - "Day 1 - 30 Min Post-dose", - "Day 1 - 1h Post-dose", - "Day 1 - 1.5h Post-dose", - "Day 1 - 2h Post-dose", - "Day 1 - 4h Post-dose", - "Day 1 - 0-6h Post-dose", - "Day 1 - 6h Post-dose", - "Day 1 - 8h Post-dose", - "Day 1 - 6-12h Post-dose", - "Day 1 - 12h Post-dose", - "Day 1 - 16h Post-dose", - "Day 1 - 12-24h Post-dose", - "Day 2 - 24h Post-dose", - "Day 2 - Pre-dose", - "Day 2 - 36h Post-dose", - "Day 2 - 24-48h Post-dose", - "Day 3 - 48h Post-dose", - "Day 3 - Pre-dose" - ))) + filter(PARAMCD == paramcd) |> # If not required this filter can be removed + select(STUDYID, USUBJID, AVISIT, AVISITN, any_of(c("ATPT", "ATPTN")), CRIT1FL) |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) + + +# derive selvisit from data, ordered by AVISITN then ATPTN +selvisit <- if (use_atpt) { + adpc |> + arrange(AVISITN, ATPTN) |> + distinct(AVISIT, ATPT) |> + mutate(AVISIT_ATPT = paste(AVISIT, ATPT, sep = ", ")) |> + pull(AVISIT_ATPT) +} else { + adpc |> + arrange(AVISITN) |> + distinct(AVISIT) |> + pull(AVISIT) +} + + +adpc <- adpc |> + # Concatenate or use AVISIT only depending on use_atpt + mutate( + AVISIT_ATPT = factor( + if (use_atpt) paste(AVISIT, ATPT, sep = ", ") else as.character(AVISIT), + levels = selvisit + ) + ) ################################################################################ # Define layout and build table: @@ -124,24 +121,25 @@ lyt <- basic_table() |> afun = a_freq_j, extra_args = list( val = "Y", - label = "Number of subjects with values below LLOQxMRD, n (%)", + label = paste0("Number of subjects with values below ", lloq_label, ", n (%)"), .stats = "count_unique_fraction", .indent_mods = 1 ) ) -result <- build_table(lyt, df = adpc, alt_counts_df = adsl) +result <- build_table(lyt, df = adpc, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table: ################################################################################ + colwidth <- c(64, 23, 23, 25) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tpkada01.R b/tests/testthat/source_code/tpkada01.R new file mode 100644 index 00000000..f49257de --- /dev/null +++ b/tests/testthat/source_code/tpkada01.R @@ -0,0 +1,209 @@ +library(envsetup) +library(dplyr) +library(tidyr) +library(forcats) +library(rtables) +library(tern) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TPKADA01" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +popfl <- "PKFL" +trtvar <- "TRT01A" +paramcd <- "XAN" +treatment_label <- "Antibodies to Active Study Agent" + +# flag to indicate if ATPT is present in the study +# if TRUE, time point is concatenation of AVISIT and ATPT +# if FALSE, time point is AVISIT only +use_atpt <- TRUE + +# Flags indicating whether to include certain statistics in the table +add_cv <- TRUE +add_interquartile_range <- TRUE + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + select(STUDYID, USUBJID, all_of(c(trtvar, popfl))) |> + filter(.data[[trtvar]] != "Placebo") |> + mutate({{ trtvar }} := fct_drop(.data[[trtvar]])) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ) + ) + + +adpc <- adpc_jnj |> + filter(PARAMCD == paramcd) |> # If not required this filter can be removed + select(STUDYID, USUBJID, AVISIT, AVISITN, any_of(c("ATPT", "ATPTN")), AVAL) + +ada_status_levels <- c( + paste0("Positive for Treatment-emergent", treatment_label, "~[super b]"), + paste0("Negative for Treatment-emergent", treatment_label, "~[super c]") +) + +adishum <- adishum_jnj |> + filter(PARAMCD %in% c("ADATRE", "ADANTRE") & IMEVFL == "Y") |> + select(STUDYID, USUBJID, AVALC, IMEVFL, PARAMCD) |> + tidyr::pivot_wider( + id_cols = c(STUDYID, USUBJID, IMEVFL), + names_from = PARAMCD, + values_from = AVALC + ) |> + mutate( + ADA_STATUS = factor( + dplyr::case_when( + ADATRE == "Y" ~ paste0("Positive for Treatment-emergent", treatment_label, "~[super b]"), + ADANTRE == "Y" ~ paste0("Negative for Treatment-emergent", treatment_label, "~[super c]"), + TRUE ~ NA_character_ + ), + levels = ada_status_levels + ) + ) |> + filter(!is.na(ADA_STATUS)) + +adpc_final <- adpc |> + inner_join(adishum, by = c("STUDYID", "USUBJID")) |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) + + +# derive selvisit from data, ordered by AVISITN then ATPTN +selvisit <- if (use_atpt) { + adpc_final |> + arrange(AVISITN, ATPTN) |> + distinct(AVISIT, ATPT) |> + mutate(AVISIT_ATPT = paste(AVISIT, ATPT, sep = " - ")) |> + pull(AVISIT_ATPT) +} else { + adpc_final |> + arrange(AVISITN) |> + distinct(AVISIT) |> + pull(AVISIT) +} + +adpc_final <- adpc_final |> + mutate( + AVISIT_ATPT = factor( + if (use_atpt) paste(AVISIT, ATPT, sep = " - ") else as.character(AVISIT), + levels = selvisit + ) + ) + + +# trick for alt_counts_df to work with col splitting +# add ADA_STATUS to adsl, assign all to extra level "N" (column will be used for N counts) +adslx <- adsl |> + mutate( + ADA_STATUS = factor("N", levels = c("N", ada_status_levels)) + ) + +################################################################################ +# Define layout and build table: +################################################################################ + +lyt <- basic_table() |> + split_cols_by( + var = trtvar, + show_colcounts = TRUE, + colcount_format = "N=xx" + ) |> + split_cols_by( + var = "ADA_STATUS", + split_fun = drop_split_levels + ) |> + analyze( + vars = "IMEVFL", + show_labels = "hidden", + section_div = " ", + afun = a_freq_j, + extra_args = list( + val = "Y", + label = "Subjects with evaluable samples~[super a]", + .stats = "count_unique" + ) + ) |> + split_rows_by( + var = "AVISIT_ATPT", + split_label = "Time Point", + label_pos = "topleft", + section_div = " ", + indent_mod = 1L + ) |> + analyze( + vars = "AVAL", + afun = a_summary, + extra_args = list( + .stats = c( + "n", + "mean_sd", + "median", + "range", + if (add_cv) "cv" else NULL, + if (add_interquartile_range) "quantiles" else NULL + ), + .labels = c( + n = "N", + mean_sd = "Mean (SD)", + median = "Median", + range = "Min, max", + cv = "CV (%)", + quantiles = "Interquartile range" + ), + .formats = c( + n = jjcsformat_xx("xx"), + mean_sd = format_sigfig_j(3, format = "xx (xx)"), + median = format_sigfig_j(3, format = "xx"), + range = format_sigfig_j(3, format = "(xx, xx)"), + cv = jjcsformat_xx("xx.x"), + quantiles = format_sigfig_j(3, format = "(xx, xx)") + ), + control = control_analyze_vars( + quantiles = c(0.25, 0.75), + quantile_type = 2 + ), + .indent_mods = c( + n = 0, + mean_sd = 1, + median = 1, + range = 1, + cv = 1, + quantiles = 1 + ) + ) + ) + + +result <- build_table(lyt, df = adpc_final, alt_counts_df = adslx, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 29, 31, 29, 29) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tpkada01titer.R b/tests/testthat/source_code/tpkada01titer.R new file mode 100644 index 00000000..5947d05f --- /dev/null +++ b/tests/testthat/source_code/tpkada01titer.R @@ -0,0 +1,326 @@ +library(envsetup) +library(dplyr) +library(forcats) +library(rtables) +library(tern) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TPKADA01titer" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +popfl <- "PKFL" +trtvar <- "TRT01A" +paramcd <- "XAN" +treatment_label <- "Antibodies to Active Study Agent" + +# flag to indicate if ATPT is present in the study +# if TRUE, time point is concatenation of AVISIT and ATPT +# if FALSE, time point is AVISIT only +use_atpt <- TRUE + +# Flags indicating whether to include certain statistics in the table +add_interquartile_range <- TRUE + +# Titer category levels from ADISHUM AVALCAT1 (PARAMCD = ADATREPT) +# Order should match the mock shell: <10, 10 to <100, 100 to <1000, >=1000 +titer_levels <- c("<10", "10 to <100", "100 to <1000", ">=1000") + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + select(STUDYID, USUBJID, all_of(c(trtvar, popfl))) |> + filter(.data[[trtvar]] != "Placebo") |> + mutate({{ trtvar }} := fct_drop(.data[[trtvar]])) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ) + ) + +adpc <- adpc_jnj |> + filter(is.null(paramcd) | PARAMCD == paramcd) |> # If not required this filter can be removed + select(STUDYID, USUBJID, AVISIT, AVISITN, any_of(c("ATPT", "ATPTN")), AVAL) + +ada_status_levels <- c( + paste0("Negative for Treatment-emergent ", treatment_label, "~[super a]"), + paste0("Positive for Treatment-emergent ", treatment_label, "~[super b]") +) + +# ADA status columns: ADANTRE (Negative) and ADATRE (Positive) +adishum_ada <- adishum_jnj |> + filter(PARAMCD %in% c("ADATRE", "ADANTRE") & IMEVFL == "Y") |> + select(STUDYID, USUBJID, AVALC, IMEVFL, PARAMCD) |> + tidyr::pivot_wider( + id_cols = c(STUDYID, USUBJID, IMEVFL), + names_from = PARAMCD, + values_from = AVALC, + values_fn = dplyr::first + ) |> + mutate( + ADA_STATUS = factor( + dplyr::case_when( + ADATRE == "Y" ~ paste0("Positive for Treatment-emergent ", treatment_label, "~[super b]"), + ADANTRE == "Y" ~ paste0("Negative for Treatment-emergent ", treatment_label, "~[super a]"), + TRUE ~ NA_character_ + ), + levels = ada_status_levels + ) + ) |> + filter(!is.na(ADA_STATUS)) + +# Titer columns: ADATREPT with AVALCAT1 categories — only Positive subjects +adishum_titer <- adishum_jnj |> + filter(PARAMCD == "ADATREPT" & IMEVFL == "Y") |> + select(STUDYID, USUBJID, AVALC, AVALCAT1, IMEVFL) |> + mutate( + TITER_CAT = factor( + AVALCAT1, + levels = titer_levels + ) + ) |> + filter(!is.na(TITER_CAT)) + +# Spanning header for titer columns +titer_header <- paste( + "Peak Titers for Subjects Positive for Treatment-emergent", + treatment_label +) + +# Join adpc with ADA status (many-to-many: one row per ADA status per PK record) +adpc_ada <- adpc |> + inner_join(adishum_ada, by = c("STUDYID", "USUBJID")) |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) |> + mutate( + ADA_STATUS = factor(as.character(ADA_STATUS), levels = ada_status_levels) + ) + +# Join adpc with titer categories (only Positive subjects with titer data) +adpc_titer <- adpc |> + inner_join(adishum_titer, by = c("STUDYID", "USUBJID")) |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) |> + mutate( + ADA_STATUS = factor(as.character(TITER_CAT), levels = titer_levels), + TITER_HEADER = factor(titer_header, levels = titer_header) + ) |> + select(-TITER_CAT) + +# derive selvisit from combined data, ordered by AVISITN then ATPTN +selvisit <- if (use_atpt) { + bind_rows(adpc_ada, adpc_titer) |> + arrange(AVISITN, ATPTN) |> + distinct(AVISIT, ATPT) |> + mutate(AVISIT_ATPT = paste(AVISIT, ATPT, sep = ", ")) |> + pull(AVISIT_ATPT) +} else { + bind_rows(adpc_ada, adpc_titer) |> + arrange(AVISITN) |> + distinct(AVISIT) |> + pull(AVISIT) +} + +adpc_ada <- adpc_ada |> + mutate( + AVISIT_ATPT = factor( + if (use_atpt) paste(AVISIT, ATPT, sep = ", ") else as.character(AVISIT), + levels = selvisit + ), + BLANK_HEADER = factor(" ", levels = " ") + ) + +adpc_titer <- adpc_titer |> + mutate( + AVISIT_ATPT = factor( + if (use_atpt) paste(AVISIT, ATPT, sep = ", ") else as.character(AVISIT), + levels = selvisit + ) + ) + +# alt_counts_df for ADA status table — one row per subject per ADA status level +adslx_ada <- adishum_ada |> + select(STUDYID, USUBJID, ADA_STATUS) |> + distinct() |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) |> + mutate(BLANK_HEADER = factor(" ", levels = " ")) + +# alt_counts_df for titer table — one row per subject per titer level +adslx_titer <- adishum_titer |> + select(STUDYID, USUBJID, TITER_CAT) |> + distinct() |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) |> + mutate( + ADA_STATUS = factor(as.character(TITER_CAT), levels = titer_levels), + TITER_HEADER = factor(titer_header, levels = titer_header) + ) |> + select(-TITER_CAT) + + +# Table 1: ADA status columns (Negative + Positive) — blank top-level span to match tbl_titer header depth +# adpc_ada <- adpc_ada |> mutate(BLANK_HEADER = factor(" ", levels = " ")) +# adslx_ada <- adslx_ada |> mutate(BLANK_HEADER = factor(" ", levels = " ")) + +################################################################################ +# Define layout and build table: +################################################################################ + +# Shared analyze layout helper (reused for both tables) +lyt_analyze <- function(lyt) { + lyt |> + analyze( + vars = "IMEVFL", + show_labels = "hidden", + section_div = " ", + afun = a_freq_j, + extra_args = list( + val = "Y", + label = "Subjects with evaluable samples~[super c]", + .stats = "count_unique" + ) + ) |> + split_rows_by( + var = "AVISIT_ATPT", + split_label = "Time Point", + label_pos = "topleft", + section_div = " " + ) |> + analyze( + vars = "AVAL", + afun = a_summary, + extra_args = list( + .stats = c( + "n", + "mean_sd", + "median", + "range", + if (add_interquartile_range) "quantiles" else NULL + ), + .labels = c( + n = "N", + mean_sd = "Mean (SD)", + median = "Median", + range = "Min, max", + quantiles = "Interquartile range" + ), + .formats = c( + n = jjcsformat_xx("xx"), + mean_sd = format_sigfig_j(3, format = "xx (xx)"), + median = format_sigfig_j(3, format = "xx"), + range = format_sigfig_j(3, format = "(xx, xx)"), + quantiles = format_sigfig_j(3, format = "(xx, xx)") + ), + control = control_analyze_vars( + quantiles = c(0.25, 0.75), + quantile_type = 2 + ), + .indent_mods = c( + n = 0, + mean_sd = 1, + median = 1, + range = 1, + quantiles = 1 + ) + ) + ) +} + + +lyt_ada <- basic_table() |> + split_cols_by( + var = "BLANK_HEADER", + nested = FALSE + ) |> + split_cols_by( + var = "ADA_STATUS", + split_fun = keep_split_levels(ada_status_levels), + show_colcounts = TRUE, + colcount_format = "N=xx" + ) |> + lyt_analyze() + +tbl_ada <- build_table(lyt_ada, df = adpc_ada, alt_counts_df = adslx_ada, round_type = "sas") + +# Table 2: Titer columns under spanning header +lyt_titer <- basic_table() |> + split_cols_by( + var = "TITER_HEADER", + nested = FALSE + ) |> + split_cols_by( + var = "ADA_STATUS", + split_fun = keep_split_levels(titer_levels), + show_colcounts = TRUE, + colcount_format = "N=xx" + ) |> + lyt_analyze() + +tbl_titer <- build_table(lyt_titer, df = adpc_titer, alt_counts_df = adslx_titer, round_type = "sas") + +# Combine both tables +result <- cbind_rtables(tbl_ada, tbl_titer) + +# Post-cbind: fix indentation lost during cbind +# Bump each AVISIT_ATPT subtree (time point label + its children) by 1 +for (lv in levels(adpc_ada$AVISIT_ATPT)) { + tryCatch( + { + path <- c("AVISIT_ATPT", lv) + indent_mod(tt_at_path(result, path)) <- indent_mod(tt_at_path(result, path)) + 1L + }, + error = function(e) NULL + ) + # N row should be one level less indented than the other stats + tryCatch( + { + path <- c("AVISIT_ATPT", lv, "AVAL", "n") + indent_mod(tt_at_path(result, path)) <- indent_mod(tt_at_path(result, path)) - 1L + }, + error = function(e) NULL + ) + # N row should be one level less indented than the other stats + tryCatch( + { + path <- c("AVISIT_ATPT", lv, "AVAL") + indent_mod(tt_at_path(result, path)) <- indent_mod(tt_at_path(result, path)) + 1L + }, + error = function(e) NULL + ) +} + +# Create section dividers for each timepoint. Due to cbind intial section division removed. +section_div_at_path(result, "IMEVFL") <- " " +for (lv in levels(adpc_ada$AVISIT_ATPT)) { + tryCatch( + section_div_at_path(result, c("AVISIT_ATPT", lv)) <- " ", + error = function(e) NULL + ) +} + + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 31, 31, 31, 31, 31, 31) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae01a.R b/tests/testthat/source_code/tsfae01a.R index 41ae763f..2c05f1e1 100644 --- a/tests/testthat/source_code/tsfae01a.R +++ b/tests/testthat/source_code/tsfae01a.R @@ -1,32 +1,9 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae01a -## R version: 4.2.1 -## Short Description: Program to create tsfae01a: Overall Summary of -## Adverse Events -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adae.RDS -## Output: tsfae01a.rtf -## Remarks: This variant includes summary of AEs by max severity. -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(stringr) ################################################################################ # Define script level parameters: @@ -41,38 +18,86 @@ tab_titles <- list( subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) +combined_colspan_trt <- TRUE +risk_diff <- TRUE +ctrl_grp <- "Placebo" +combination_trt <- FALSE # Provide whether this is a combination treatments study + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc + comb_acnvars <- paste0("AEACNS", seq_len(n_comb_trt)) # This will create a variable list like AEACNS1, AEACNS2 etc + comb_suffix <- seq_len(n_comb_trt) +} else if (!combination_trt) { + comb_trtvars <- trtvar + comb_relvars <- "AEREL" + comb_acnvars <- "AEACN" + comb_suffix <- "" +} ################################################################################ # Process data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> create_colspan_var( - non_active_grp = "Placebo", + non_active_grp = ctrl_grp, non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% - mutate( - rrisk_header = "Risk Difference (%) (95% CI)", - rrisk_label = paste(!!rlang::sym(trtvar), "vs Placebo") - ) %>% + ) |> select( USUBJID, !!rlang::sym(popfl), !!rlang::sym(trtvar), - colspan_trt, - rrisk_header, - rrisk_label + colspan_trt ) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +if (risk_diff == TRUE) { + adsl$rrisk_header <- "Risk Difference (%) (95% CI)" + adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) +} + + +adae <- adae_jnj |> + filter(TRTEMFL == "Y") |> select( USUBJID, + all_of(comb_trtvars), AESER, AESDTH, AESLIFE, @@ -80,15 +105,74 @@ adae <- adae_jnj %>% AESDISAB, AESCONG, AESMIE, - AEACN_DECODE, - AESEV - ) %>% - group_by(USUBJID) %>% - mutate(maxsev = max(as.character(AESEV), na.rm = TRUE)) %>% - ungroup() %>% - mutate(maxsev = ifelse(is.na(maxsev), "Missing", maxsev)) %>% + all_of(comb_acnvars), + AESEV, + ASEVN, + all_of(comb_relvars), + TRDISCFL, + AEOUT, + AOCCIFL, + TRTEMFL + ) |> + group_by(USUBJID) |> + mutate(maxsev = ASEVN[which(AOCCIFL == "Y")][1]) |> + ungroup() |> + mutate(maxsev = ifelse(is.na(maxsev), "Missing", maxsev)) |> + mutate( + maxsev = factor( + maxsev, + levels = c( + "1", + "2", + "3", + "Missing" + ), + labels = c( + "Mild", + "Moderate", + "Severe", + "Missing" + ) + ) + ) |> + (\(z) { + df <- z + + df |> + mutate( + !!!setNames( + lapply(comb_relvars, function(x) { + if_else( + df$AESER == "Y" & df[[x]] == "RELATED", + "Y", + NA_character_ + ) + }), + paste0("Rel_SAEs", comb_suffix) + ), + !!!setNames( + lapply(comb_relvars, function(x) { + if_else( + df$AEOUT == "FATAL" & df[[x]] == "RELATED", + "Y", + NA_character_ + ) + }), + paste0("Rel_AE_Death", comb_suffix) + ) + ) + })() |> mutate( - maxsev = factor(maxsev, levels = c("Mild", "Moderate", "Severe", "Missing")) + across( + all_of(comb_acnvars), + ~ { + levels(.) <- str_to_sentence(levels(.)) + . + } + ) + ) |> + select( + -any_of(trtvar) ) adae <- inner_join(adae, adsl, by = c("USUBJID")) @@ -97,9 +181,36 @@ adae <- inner_join(adae, adsl, by = c("USUBJID")) # Define layout and build table: ################################################################################ +if (combination_trt) { + comb_rel_ae_labels <- paste(sapply(comb_trtvars, \(x) unique(adae[[x]])[1]), "related AEs") + + comb_rel_sae_vars <- paste0("Rel_SAEs", seq_len(n_comb_trt)) + comb_rel_sae_labels <- paste(sapply(comb_trtvars, \(x) unique(adae[[x]])[1]), "related SAEs") + + comb_rel_aedth_vars <- paste0("Rel_AE_Death", seq_len(n_comb_trt)) + comb_rel_aedth_labels <- paste(sapply(comb_trtvars, \(x) unique(adae[[x]])[1]), "related AEs leading to death") + + comb_acn_labels <- paste( + "AE leading to dose modification of study treatment", + sapply(comb_trtvars, \(x) tolower(unique(adae[[x]])[1])), + "~[super a,b]" + ) +} else if (!combination_trt) { + comb_rel_ae_labels <- "Related AEs" + + comb_rel_sae_vars <- "Rel_SAEs" + comb_rel_sae_labels <- "Related SAEs" + + comb_rel_aedth_vars <- "Rel_AE_Death" + comb_rel_aedth_labels <- "Related AEs leading to death" + + comb_acn_labels <- "AE leading to dose modification of study treatment~[super a,b]" +} + + colspan_trt_map <- create_colspan_map( adsl, - non_active_grp = "Placebo", + non_active_grp = ctrl_grp, non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", @@ -107,40 +218,37 @@ colspan_trt_map <- create_colspan_map( ) ################################## -# Check the levels of AEACN_DECODE +# Check the levels of AEACN ################################## -aeacn_levels <- levels(adae$AEACN_DECODE) +aeacn_levels <- adae |> + select(all_of(comb_acnvars)) |> + lapply(levels) |> + unlist(use.names = FALSE) |> + unique() |> + str_to_sentence() + # Here we are not considering "Drug Withdrawn", "Dose Not Changed", "Not Applicable" -excl_aeacn_levels <- c("Drug Withdrawn", "Dose Not Changed", "Not Applicable") +excl_aeacn_levels <- c("Drug withdrawn", "Dose not changed", "Not applicable", "Unknown") dosemod_lvls <- aeacn_levels[!(aeacn_levels %in% excl_aeacn_levels)] -## rearrange levels for AEACN_DECODE +## rearrange levels for AEACN -newsort_AEACN_DECODE <- unique(c( - "Drug Interrupted", - "Dose Reduced", - "Dose Rate Reduced", - "Dose Increased", - "Unknown", +newsort_AEACN <- unique(c( + "Drug interrupted", + "Dose reduced", + "Dose rate reduced", + "Dose increased", aeacn_levels )) -adae$AEACN_DECODE <- forcats::fct_relevel( - adae$AEACN_DECODE, - newsort_AEACN_DECODE -) - -## mapping table for label updates -dosemod_lblmap <- tibble(value = dosemod_lvls, label = dosemod_lvls) %>% +adae <- adae |> mutate( - label = case_when( - value == "Dose Increased" ~ label, - value == "Dose Reduced" ~ "Reduction of study treatment", - value == "Drug Interrupted" ~ "Interruption of study treatment", - TRUE ~ label + across( + all_of(comb_acnvars), + ~ forcats::fct_relevel(., newsort_AEACN) ) ) @@ -149,22 +257,27 @@ dosemod_spf <- make_combo_splitfun( nm = "modified", label = "AE leading to dose modification of study", levels = c( - "Dose Reduced", - "Dose Increased", - "Drug Interrupted", - "Dose Rate Reduced", - "Unknown" + "Dose reduced", + "Dose increased", + "Drug interrupted", + "Dose rate reduced" ) ) aesevall_spf <- make_combo_splitfun( nm = "AESEV_ALL", - label = "Any AE~[super a]", + label = "Worst severity", levels = NULL ) +sae_class <- make_combo_splitfun( + nm = "SAE_CLASS", + label = "SAE classification~[super b]", + levels = "Y" +) + rr_method <- "wald" -ref_path <- c("colspan_trt", " ", trtvar, "Placebo") +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) extra_args_rr <- list( method = rr_method, ref_path = ref_path, @@ -175,43 +288,153 @@ lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx", top_level_section_div = " " -) %>% - append_topleft(c(" ", " ", "Event, n (%)")) %>% +) |> + append_topleft(c(" ", " ", "Event, n (%)")) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (risk_diff == TRUE) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels("Placebo") + ) +} + +lyt <- lyt |> split_rows_by( - "AESER", + "TRTEMFL", split_fun = keep_split_levels("Y"), section_div = " " - ) %>% + ) |> summarize_row_groups( - "AESER", + "TRTEMFL", cfun = a_freq_j, extra_args = list( - label = "SAE", + label = "AEs", method = rr_method, ref_path = ref_path, .stats = c("count_unique_fraction") ) - ) %>% + ) |> + analyze( + "AESER", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "SAEs", val = "Y", NULL) + ) + ) + +for (i in seq_along(comb_relvars)) { + lyt <- lyt |> + analyze( + comb_relvars[i], + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = comb_rel_ae_labels[i], val = toupper("Related"), NULL) + ) + ) |> + analyze( + comb_rel_sae_vars[i], + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = comb_rel_sae_labels[i], val = "Y", NULL) + ) + ) +} + +lyt <- lyt |> + analyze( + "TRDISCFL", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "AE leading to permanent discontinuation of study treatment", val = "Y", NULL) + ) + ) + +for (i in seq_along(comb_rel_aedth_vars)) { + lyt <- lyt |> + analyze( + comb_rel_aedth_vars[i], + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = comb_rel_aedth_labels[i], val = "Y", NULL) + ) + ) +} + +lyt <- lyt |> + split_rows_by("maxsev", split_fun = aesevall_spf) |> + analyze("maxsev", afun = a_freq_j, extra_args = append(extra_args_rr, NULL)) + + +for (i in seq_along(comb_acnvars)) { + lyt <- lyt |> + split_rows_by(comb_acnvars[i], split_fun = dosemod_spf, section_div = " ") |> + summarize_row_groups( + comb_acnvars[i], + cfun = a_freq_j, + extra_args = list( + label = comb_acn_labels[i], + method = rr_method, + ref_path = ref_path, + .stats = c("count_unique_fraction") + ) + ) |> + analyze( + comb_acnvars[i], + table_names = comb_acnvars[i], + a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list( + excl_levels = excl_aeacn_levels, + # label_map = dosemod_lblmap, + drop_levels = TRUE + ) + ) + ) +} + + +lyt <- lyt |> + split_rows_by( + "AESER", + split_fun = sae_class, + section_div = " ", + ) |> analyze( "AESDTH", afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list(label = "With fatal outcome", val = "Y", NULL) + list(label = "Death", val = "Y", NULL) ) - ) %>% + ) |> analyze( "AESLIFE", afun = a_freq_j, @@ -220,16 +443,16 @@ lyt <- basic_table( extra_args_rr, list(label = "Life-threatening", val = "Y", NULL) ) - ) %>% + ) |> analyze( "AESHOSP", afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list(label = "Requiring or prolonging hospitalization", val = "Y", NULL) + list(label = "Requires or prolongs hospitalization", val = "Y", NULL) ) - ) %>% + ) |> analyze( "AESDISAB", afun = a_freq_j, @@ -237,12 +460,12 @@ lyt <- basic_table( extra_args = append( extra_args_rr, list( - label = "Resulting in persistent or significant disability/incapacity", + label = "Persistent or significant disability/incapacity", val = "Y", NULL ) ) - ) %>% + ) |> analyze( "AESCONG", afun = a_freq_j, @@ -251,66 +474,16 @@ lyt <- basic_table( extra_args_rr, list(label = "Congenital anomaly or birth defect", val = "Y", NULL) ) - ) %>% + ) |> analyze( "AESMIE", afun = a_freq_j, show_labels = "hidden", - extra_args = append(extra_args_rr, list(label = "Other", val = "Y", NULL)) - ) %>% - analyze( - "AEACN_DECODE", - afun = a_freq_j, - nested = FALSE, - extra_args = append( - extra_args_rr, - list( - label = "AE leading to permanent discontinuation of study treatment", - val = "Drug Withdrawn", - NULL - ) - ) - ) %>% - split_rows_by("AEACN_DECODE", split_fun = dosemod_spf, section_div = " ") %>% - summarize_row_groups( - "AEACN_DECODE", - cfun = a_freq_j, - extra_args = list( - label = "AE leading to dose modification of study treatment", - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") - ) - ) %>% - analyze( - "AEACN_DECODE", - table_names = "AEACN_DECODE", - a_freq_j, - show_labels = "hidden", - extra_args = append( - extra_args_rr, - list( - excl_levels = excl_aeacn_levels, - label_map = dosemod_lblmap, - drop_levels = TRUE - ) - ) - ) %>% - split_rows_by("maxsev", split_fun = aesevall_spf) %>% - summarize_row_groups( - "maxsev", - cfun = a_freq_j, - extra_args = list( - label = "Any AE~[super a]", - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") - ) - ) %>% - analyze("maxsev", afun = a_freq_j, extra_args = append(extra_args_rr, NULL)) + extra_args = append(extra_args_rr, list(label = "Other medically important event", val = "Y", NULL)) + ) -result <- build_table(lyt, adae, alt_counts_df = adsl) +result <- build_table(lyt, adae, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: @@ -323,12 +496,16 @@ result <- suppressWarnings(safe_prune_table( result, prune_func = count_pruner( cat_exclude = c( - "With fatal outcome", - "Life-threatening", - "Requiring or prolonging hospitalization", - "Resulting in persistent or significant disability/incapacity", - "Congenital anomaly or birth defect", - "Other" + "AEs", + "SAEs", + comb_rel_ae_labels, + comb_rel_sae_labels, + "AE leading to permanent discontinuation of any study treatment", + comb_rel_aedth_labels, + "Mild", + "Moderate", + "Severe", + comb_acn_labels ) ) )) @@ -343,6 +520,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table: ################################################################################ -colwidth <- c(64, 21, 21, 21, 30, 31) + +colwidth <- c(64, 21, 21, 21, 21, 33, 31) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae01b.R b/tests/testthat/source_code/tsfae01b.R index e666032a..ca3872f5 100644 --- a/tests/testthat/source_code/tsfae01b.R +++ b/tests/testthat/source_code/tsfae01b.R @@ -1,32 +1,9 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae01b -## R version: 4.2.1 -## Short Description: Program to create tsfae01b: Overall Summary of -## Adverse Events -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adae.RDS -## Output: tsfae01b.rtf -## Remarks: This variant includes summary of AEs by max tox grade. -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(stringr) ################################################################################ # Define script level parameters: @@ -41,52 +18,107 @@ tab_titles <- list( subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) +combined_colspan_trt <- TRUE +risk_diff <- TRUE +ctrl_grp <- "Placebo" +combination_trt <- FALSE # Provide whether this is a combination treatments study + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc + comb_acnvars <- paste0("AEACNS", seq_len(n_comb_trt)) # This will create a variable list like AEACNS1, AEACNS2 etc + comb_suffix <- seq_len(n_comb_trt) +} else if (!combination_trt) { + comb_trtvars <- trtvar + comb_relvars <- "AEREL" + comb_acnvars <- "AEACN" + comb_suffix <- "" +} ################################################################################ # Process data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> create_colspan_var( - non_active_grp = "Placebo", + non_active_grp = ctrl_grp, non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% - mutate( - rrisk_header = "Risk Difference (%) (95% CI)", - rrisk_label = paste(!!rlang::sym(trtvar), "vs Placebo") - ) %>% + ) |> select( USUBJID, !!rlang::sym(popfl), !!rlang::sym(trtvar), - colspan_trt, - rrisk_header, - rrisk_label + colspan_trt ) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +if (risk_diff == TRUE) { + adsl$rrisk_header <- "Risk Difference (%) (95% CI)" + adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) +} + +adae <- adae_jnj |> + filter(TRTEMFL == "Y") |> select( USUBJID, + all_of(comb_trtvars), + all_of(comb_acnvars), + all_of(comb_relvars), + TRTEMFL, AESER, + AESMIE, + AETOXGR, + AETOXGRN, + AEACN, + AEOUT, + AOCTIFL, + TRDISCFL, AESDTH, AESLIFE, AESHOSP, AESDISAB, AESCONG, - AESMIE, - AEACN_DECODE, - AETOXGR - ) %>% - group_by(USUBJID) %>% - mutate(maxtox = max(as.character(AETOXGR), na.rm = TRUE)) %>% - ungroup() %>% - mutate(maxtox = ifelse(is.na(maxtox), "Missing", paste("Grade", maxtox))) %>% + AESMIE + ) |> + group_by(USUBJID) |> + mutate(maxtox = AETOXGRN[which(AOCTIFL == "Y")][1], maxtoxcm = ifelse(maxtox >= "3", "Y", NA)) |> + ungroup() |> + mutate(maxtox = ifelse(is.na(maxtox), "Missing", paste("Grade", maxtox))) |> mutate( maxtox = factor( maxtox, @@ -99,6 +131,45 @@ adae <- adae_jnj %>% "Missing" ) ) + ) |> + (\(z) { + df <- z + + df |> + mutate( + !!!setNames( + lapply(comb_relvars, function(x) { + if_else( + df$AESER == "Y" & df[[x]] == "RELATED", + "Y", + NA_character_ + ) + }), + paste0("Rel_SAEs", comb_suffix) + ), + !!!setNames( + lapply(comb_relvars, function(x) { + if_else( + df$AEOUT == "FATAL" & df[[x]] == "RELATED", + "Y", + NA_character_ + ) + }), + paste0("Rel_AE_Death", comb_suffix) + ) + ) + })() |> + mutate( + across( + all_of(comb_acnvars), + ~ { + levels(.) <- str_to_sentence(levels(.)) + . + } + ) + ) |> + select( + -any_of(trtvar) ) @@ -108,9 +179,36 @@ adae <- inner_join(adae, adsl, by = c("USUBJID")) # Define layout and build table: ################################################################################ +if (combination_trt) { + comb_rel_ae_labels <- paste(sapply(comb_trtvars, \(x) unique(adae[[x]])[1]), "related AEs") + + comb_rel_sae_vars <- paste0("Rel_SAEs", seq_len(n_comb_trt)) + comb_rel_sae_labels <- paste(sapply(comb_trtvars, \(x) unique(adae[[x]])[1]), "related SAEs") + + comb_rel_aedth_vars <- paste0("Rel_AE_Death", seq_len(n_comb_trt)) + comb_rel_aedth_labels <- paste(sapply(comb_trtvars, \(x) unique(adae[[x]])[1]), "related AEs leading to death") + + comb_acn_labels <- paste( + "AE leading to dose modification of study treatment", + sapply(comb_trtvars, \(x) tolower(unique(adae[[x]])[1])), + "~[super b,c]" + ) +} else if (!combination_trt) { + comb_rel_ae_labels <- "Related AEs" + + comb_rel_sae_vars <- "Rel_SAEs" + comb_rel_sae_labels <- "Related SAEs" + + comb_rel_aedth_vars <- "Rel_AE_Death" + comb_rel_aedth_labels <- "Related AEs leading to death" + + comb_acn_labels <- "AE leading to dose modification of study treatment~[super b,c]" +} + + colspan_trt_map <- create_colspan_map( adsl, - non_active_grp = "Placebo", + non_active_grp = ctrl_grp, non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", @@ -118,39 +216,49 @@ colspan_trt_map <- create_colspan_map( ) ################################## -# Check the levels of AEACN_DECODE +# Check the levels of AEACN ################################## -aeacn_levels <- levels(adae$AEACN_DECODE) +aeacn_levels <- adae |> + select(all_of(comb_acnvars)) |> + lapply(levels) |> + unlist(use.names = FALSE) |> + unique() |> + str_to_sentence() + # Here we are not considering "Drug Withdrawn", "Dose Not Changed", "Not Applicable" -excl_aeacn_levels <- c("Drug Withdrawn", "Dose Not Changed", "Not Applicable") +excl_aeacn_levels <- c("Drug withdrawn", "Dose not changed", "Not applicable", "Unknown") dosemod_lvls <- aeacn_levels[!(aeacn_levels %in% excl_aeacn_levels)] ## rearrange levels for AEACN_DECODE -newsort_AEACN_DECODE <- unique(c( - "Drug Interrupted", - "Dose Reduced", - "Dose Rate Reduced", - "Dose Increased", - "Unknown", +newsort_AEACN <- unique(c( + "Drug interrupted", + "Dose reduced", + "Dose rate reduced", + "Dose increased", aeacn_levels )) -adae$AEACN_DECODE <- forcats::fct_relevel( - adae$AEACN_DECODE, - newsort_AEACN_DECODE -) + +adae <- adae |> + mutate( + across( + all_of(comb_acnvars), + ~ forcats::fct_relevel(., newsort_AEACN) + ) + ) + ## mapping table for label updates -dosemod_lblmap <- tibble(value = dosemod_lvls, label = dosemod_lvls) %>% +dosemod_lblmap <- tibble(value = dosemod_lvls, label = dosemod_lvls) |> mutate( label = case_when( - value == "Dose Increased" ~ label, - value == "Dose Reduced" ~ "Reduction of study treatment", - value == "Drug Interrupted" ~ "Interruption of study treatment", + value == "Dose increased" ~ label, + value == "Dose reduced" ~ "Reduction of study treatment", + value == "Drug interrupted" ~ "Interruption of study treatment", TRUE ~ label ) ) @@ -159,20 +267,26 @@ dosemod_lblmap <- tibble(value = dosemod_lvls, label = dosemod_lvls) %>% dosemod_spf <- make_combo_splitfun( nm = "modified", label = "AE leading to dose modification of study", - levels = c("Dose Reduced", "Dose Increased", "Drug Interrupted", "Unknown") + levels = c("Dose reduced", "Dose increased", "Drug interrupted", "Dose rate reduced") ) aesevall_spf <- make_combo_splitfun( nm = "AESEV_ALL", - label = "Any AE~[super a]", + label = "Worst toxicity grade~[super a]", levels = NULL ) +aeserall_spf <- make_combo_splitfun( + nm = "AESER_ALL", + label = "SAE classification~[super c]", + levels = "Y" +) + ################################################################################ # Define layout and build table: ################################################################################ rr_method <- "wald" -ref_path <- c("colspan_trt", " ", trtvar, "Placebo") +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) extra_args_rr <- list( method = rr_method, ref_path = ref_path, @@ -183,142 +297,218 @@ lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx", top_level_section_div = " " -) %>% - append_topleft(c(" ", " ", "Event, n (%)")) %>% +) |> + append_topleft(c(" ", " ", "Event, n (%)")) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (risk_diff == TRUE) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels("Placebo") + ) +} + +lyt <- lyt |> split_rows_by( - "AESER", + "TRTEMFL", split_fun = keep_split_levels("Y"), section_div = " " - ) %>% + ) |> summarize_row_groups( - "AESER", + "TRTEMFL", cfun = a_freq_j, extra_args = list( - label = "SAE", + label = "AEs", method = rr_method, ref_path = ref_path, .stats = c("count_unique_fraction") ) - ) %>% + ) |> analyze( - "AESDTH", + "AESER", afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list(label = "With fatal outcome", val = "Y", NULL) + list(label = "SAEs", val = "Y", NULL) + ) + ) + +for (i in seq_along(comb_relvars)) { + lyt <- lyt |> + analyze( + comb_relvars[i], + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = comb_rel_ae_labels[i], val = toupper("Related"), NULL) + ) + ) |> + analyze( + comb_rel_sae_vars[i], + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = comb_rel_sae_labels[i], val = "Y", NULL) + ) ) - ) %>% +} + +lyt <- lyt |> analyze( - "AESLIFE", + "TRDISCFL", afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list(label = "Life-threatening", val = "Y", NULL) + list(label = "AE leading to permanent discontinuation of study treatment", val = "Y", NULL) + ) + ) + +for (i in seq_along(comb_rel_aedth_vars)) { + lyt <- lyt |> + analyze( + comb_rel_aedth_vars[i], + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = comb_rel_aedth_labels[i], val = "Y", NULL) + ) ) - ) %>% +} + +lyt <- lyt |> + split_rows_by( + "maxtox", + split_fun = aesevall_spf, + section_div = " " + ) |> analyze( - "AESHOSP", + "maxtox", + show_labels = "hidden", + afun = a_freq_j, + extra_args = append(extra_args_rr, NULL) + ) |> + analyze( + "maxtoxcm", afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list(label = "Requiring or prolonging hospitalization", val = "Y", NULL) + list(label = ">= Grade 3", val = "Y", NULL) + ) + ) + +for (i in seq_along(comb_acnvars)) { + lyt <- lyt |> + split_rows_by(comb_acnvars[i], split_fun = dosemod_spf, section_div = " ") |> + summarize_row_groups( + comb_acnvars[i], + cfun = a_freq_j, + extra_args = list( + label = comb_acn_labels[i], + method = rr_method, + ref_path = ref_path, + .stats = c("count_unique_fraction") + ) + ) |> + analyze( + comb_acnvars[i], + table_names = comb_acnvars[i], + a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list( + excl_levels = excl_aeacn_levels, + # label_map = dosemod_lblmap, + drop_levels = TRUE + ) + ) ) - ) %>% +} + +lyt <- lyt |> + split_rows_by( + "AESER", + split_fun = aeserall_spf, + section_div = " " + ) |> analyze( - "AESDISAB", + "AESDTH", afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list( - label = "Resulting in persistent or significant disability/incapacity", - val = "Y", - NULL - ) + list(label = "Death", val = "Y", NULL) ) - ) %>% + ) |> analyze( - "AESCONG", + "AESLIFE", afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list(label = "Congenital anomaly or birth defect", val = "Y", NULL) + list(label = "Life-threatening", val = "Y", NULL) ) - ) %>% + ) |> analyze( - "AESMIE", + "AESHOSP", afun = a_freq_j, show_labels = "hidden", - extra_args = append(extra_args_rr, list(label = "Other", val = "Y", NULL)) - ) %>% + extra_args = append( + extra_args_rr, + list(label = "Requires or prolongs hospitalization", val = "Y", NULL) + ) + ) |> analyze( - "AEACN_DECODE", + "AESDISAB", afun = a_freq_j, - nested = FALSE, + show_labels = "hidden", extra_args = append( extra_args_rr, list( - label = "AE leading to permanent discontinuation of study treatment", - val = "Drug Withdrawn", + label = "Persistent or significant disability/incapacity", + val = "Y", NULL ) ) - ) %>% - split_rows_by("AEACN_DECODE", split_fun = dosemod_spf, section_div = " ") %>% - summarize_row_groups( - "AEACN_DECODE", - cfun = a_freq_j, - extra_args = list( - label = "AE leading to dose modification of study treatment", - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") - ) - ) %>% + ) |> analyze( - "AEACN_DECODE", - table_names = "AEACN_DECODE", - a_freq_j, + "AESCONG", + afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list( - excl_levels = excl_aeacn_levels, - label_map = dosemod_lblmap, - drop_levels = TRUE - ) - ) - ) %>% - split_rows_by("maxtox", split_fun = aesevall_spf) %>% - summarize_row_groups( - "maxtox", - cfun = a_freq_j, - extra_args = list( - label = "Any AE~[super a]", - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") + list(label = "Congenital anomaly or birth defect", val = "Y", NULL) ) - ) %>% - analyze("maxtox", afun = a_freq_j, extra_args = append(extra_args_rr, NULL)) + ) |> + analyze( + "AESMIE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append(extra_args_rr, list(label = "Other medically important event", val = "Y", NULL)) + ) -result <- build_table(lyt, adae, alt_counts_df = adsl) +result <- build_table(lyt, adae, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: @@ -331,12 +521,19 @@ result <- suppressWarnings(safe_prune_table( result, prune_func = count_pruner( cat_exclude = c( - "With fatal outcome", - "Life-threatening", - "Requiring or prolonging hospitalization", - "Resulting in persistent or significant disability/incapacity", - "Congenital anomaly or birth defect", - "Other" + "AEs", + "SAEs", + comb_rel_ae_labels, + comb_rel_sae_labels, + "AE leading to permanent discontinuation of any study treatment", + comb_rel_aedth_labels, + "Grade 1", + "Grade 2", + "Grade 3", + "Grade 4", + "Grade 5", + ">= Grade 3", + comb_acn_labels ) ) )) @@ -351,6 +548,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table: ################################################################################ -colwidth <- c(64, 21, 21, 21, 33, 33) + +colwidth <- c(64, 21, 21, 21, 21, 30, 30) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae02.R b/tests/testthat/source_code/tsfae02.R index a9227449..693d5c2f 100644 --- a/tests/testthat/source_code/tsfae02.R +++ b/tests/testthat/source_code/tsfae02.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae02.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae02: AE table by SOC/PT - TEAEs -## Author: Johnson & Johnson Innovative Medicine -## Date: 10 Nov 2023 -## Input: ADSL, ADAE. -## Output: TSFAE02.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -82,12 +58,32 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD) adsl$colspan_trt <- factor( @@ -101,7 +97,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -134,23 +130,23 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -158,7 +154,7 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% +lyt <- lyt |> analyze( "TRTEMFL", afun = a_freq_j, @@ -166,7 +162,7 @@ lyt <- lyt %>% extra_args_rr2, list(val = "Y", label = "Subjects with >=1 AE") ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", @@ -174,16 +170,16 @@ lyt <- lyt %>% label_pos = "topleft", section_div = c(" "), nested = FALSE - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, extra_args = extra_args_rr2 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_rr2) %>% + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_rr2) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ## Remove the N=xx column headers for the risk difference columns result <- remove_col_count(result) @@ -226,6 +222,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 23, 21, 31, 33) + +colwidth <- c(64, 21, 21, 21, 21, 35, 31) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae02a.R b/tests/testthat/source_code/tsfae02a.R index a4af9a05..ee8c9582 100644 --- a/tests/testthat/source_code/tsfae02a.R +++ b/tests/testthat/source_code/tsfae02a.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae02a.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae02a: AE table by SOC/PT and Subgroup - TEAEs -## Author: Johnson & Johnson Innovative Medicine -## Date: 23 Nov 2023 -## Input: ADSL, ADAE. -## Output: TSFAE02a.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -88,12 +64,36 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl), all_of(subgrpvar)) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl), all_of(subgrpvar)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + AGEGR1 = factor( + AGEGR1, + levels = c(">=18 to <65", ">=65 to <75", ">=75") + ) + ) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD) adsl$colspan_trt <- factor( @@ -107,7 +107,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -145,23 +145,23 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -169,7 +169,7 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% +lyt <- lyt |> split_rows_by( subgrpvar, split_label = "", @@ -177,44 +177,39 @@ lyt <- lyt %>% indent_mod = -1L, section_div = c(" "), page_by = TRUE - ) %>% # Set page_by = FALSE if you do not wish to start a new page after a new subgroup + ) |> # Set page_by = FALSE if you do not wish to start a new page after a new subgroup summarize_row_groups( subgrpvar, cfun = a_freq_j, extra_args = append(extra_args_rr, list(label_fstr = subgrpvar_f)) - ) %>% - split_rows_by( - "TRTEMFL", - split_fun = keep_split_levels("Y"), - indent_mod = -1L, - section_div = c(" ") - ) %>% - summarize_row_groups( + ) |> + analyze( "TRTEMFL", - cfun = a_freq_j, + afun = a_freq_j, extra_args = append( extra_args_rr2, - list(label = "Subjects with >=1 AE", extrablankline = TRUE) + list(val = "Y", label = "Subjects with >=1 AE", extrablankline = TRUE) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", split_fun = trim_levels_in_group("AEDECOD"), label_pos = "topleft", indent_mod = 0L, - section_div = c(" ") - ) %>% + section_div = c(" "), + at_sibling = "TRTEMFL" + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, extra_args = extra_args_rr2 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_rr2) %>% + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_rr2) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ## Remove the N=xx column headers for the risk difference columns result <- remove_col_count(result) @@ -229,12 +224,12 @@ result <- remove_col_count(result) if (length(adae$TRTEMFL) != 0) { result <- sort_at_path( result, - c(subgrpvar, "*", "TRTEMFL", "*", "AEBODSYS"), + c(subgrpvar, "*", "AEBODSYS"), scorefun = jj_complex_scorefun() ) result <- sort_at_path( result, - c(subgrpvar, "*", "TRTEMFL", "*", "AEBODSYS", "*", "AEDECOD"), + c(subgrpvar, "*", "AEBODSYS", "*", "AEDECOD"), scorefun = jj_complex_scorefun() ) } @@ -249,6 +244,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 23, 21, 23, 21, 35, 35) + +colwidth <- c(64, 21, 21, 21, 21, 35, 35) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae03a.R b/tests/testthat/source_code/tsfae03a.R index 02ad274e..45fb8c80 100644 --- a/tests/testthat/source_code/tsfae03a.R +++ b/tests/testthat/source_code/tsfae03a.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae03a.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae03a: AE table by SOC/PT and Subgroup - SAEs -## Author: Johnson & Johnson Innovative Medicine -## Date: 23 Feb 2024 -## Input: ADSL, ADAE. -## Output: TSFAE03a.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -36,7 +12,6 @@ library(junco) # - Define output ID and file location # - Define treatment variable used (default=TRT01A) # - Define population flag used (default=SAFFL) -# - subgroup variable required from ADSL, and subgroup text you want as a prefix to appear in the table, and any subgroup unit needed # - Choose whether or not you want to present a combined active treatment column (default=TRUE) # - Choose whether or not you want to present the risk difference columns (default=TRUE) # - Choose which risk difference method you would like (default=Wald) @@ -55,11 +30,6 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" - -subgrpvar <- "AGEGR1" -subgrptxt <- "Age Group" -subgrpunit <- "years" - combined_colspan_trt <- TRUE risk_diff <- TRUE rr_method <- "wald" @@ -88,29 +58,33 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> mutate( - subgrpdisplay = as.factor(paste0( - subgrptxt, - ": ", - !!as.name(subgrpvar), - " ", - subgrpunit - )) - ) %>% - select( - STUDYID, - USUBJID, - all_of(trtvar), - all_of(popfl), - all_of(subgrpvar), - subgrpdisplay - ) + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & AESER == "Y") %>% - select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD) +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & AEREL == "RELATED") |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AEREL) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -123,7 +97,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- left_join(adsl, adae, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -138,104 +112,85 @@ colspan_trt_map <- create_colspan_map( # Define layout and build table: ################################################################################ -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") - +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) extra_args_rr <- list( - denom = "n_altdf", - denom_by = "subgrpdisplay", - riskdiff = FALSE, - extrablankline = TRUE, - .stats = c("n_altdf") -) - -extra_args_rr2 <- list( - denom = "n_altdf", - denom_by = "subgrpdisplay", - riskdiff = TRUE, + method = rr_method, ref_path = ref_path, - method = "wald", .stats = c("count_unique_fraction") ) + lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( - trtvar, + "TRT01A", labels_var = "rrisk_label", split_fun = remove_split_levels("Placebo") ) } -lyt <- lyt %>% - split_rows_by( - "subgrpdisplay", - split_label = "", - split_fun = trim_levels_in_group("STUDYID"), - indent_mod = -1L, - section_div = c(" "), - page_by = TRUE - ) %>% # Set page_by = FALSE if you do not wish to start a new page after a new subgroup - summarize_row_groups( - "subgrpdisplay", - cfun = a_freq_j, - indent_mod = 0L, - extra_args = extra_args_rr - ) %>% - split_rows_by( - "TRTEMFL", - split_fun = keep_split_levels("Y"), - indent_mod = -1L, - section_div = c(" ") - ) %>% - summarize_row_groups( +lyt <- lyt |> + analyze( "TRTEMFL", - cfun = a_freq_j, - indent_mod = 0L, + afun = a_freq_j, + show_labels = "hidden", extra_args = append( - extra_args_rr2, - list(label = "Subjects with >=1 SAE", extrablankline = TRUE) + extra_args_rr, + list(label = "Subjects with >=1 related AE", NULL) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", split_fun = trim_levels_in_group("AEDECOD"), label_pos = "topleft", - indent_mod = 0L, - section_div = c(" ") - ) %>% + section_div = c(" "), + nested = FALSE + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, - extra_args = extra_args_rr2 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_rr2) %>% + extra_args = append(extra_args_rr, NULL) + ) |> + analyze( + "AEDECOD", + afun = a_freq_j, + extra_args = append(extra_args_rr, NULL) + ) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ## Remove the N=xx column headers for the risk difference columns result <- remove_col_count(result) +# If there is no data remove top row and display "No data to display" text +if (length(adae$TRTEMFL) == 0) { + result <- safe_prune_table( + result, + prune_func = remove_rows(removerowtext = "Subjects with >=1 related AE") + ) +} + ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. # Default is the last treatment (inc. Combined if applicable) under the active treatment @@ -246,12 +201,12 @@ result <- remove_col_count(result) if (length(adae$TRTEMFL) != 0) { result <- sort_at_path( result, - c("subgrpdisplay", "*", "TRTEMFL", "*", "AEBODSYS"), + c("root", "AEBODSYS"), scorefun = jj_complex_scorefun() ) result <- sort_at_path( result, - c("subgrpdisplay", "*", "TRTEMFL", "*", "AEBODSYS", "*", "AEDECOD"), + c("root", "AEBODSYS", "*", "AEDECOD"), scorefun = jj_complex_scorefun() ) } @@ -266,6 +221,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 21, 35, 35) + +colwidth <- c(64, 21, 21, 21, 21, 31, 31) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae03.R b/tests/testthat/source_code/tsfae03b.R similarity index 79% rename from tests/testthat/source_code/tsfae03.R rename to tests/testthat/source_code/tsfae03b.R index 79842b7e..466b2b6e 100644 --- a/tests/testthat/source_code/tsfae03.R +++ b/tests/testthat/source_code/tsfae03b.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae03.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae03: AE table by SOC/PT - Serious TEAEs -## Author: Johnson & Johnson Innovative Medicine -## Date: 19 Jan 2024 -## Input: ADSL, ADAE. -## Output: TSFAE03.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -43,7 +19,7 @@ library(junco) # - Define how to create combined treatment columns (if required) ################################################################################ -tblid <- "TSFAE03" +tblid <- "TSFAE03b" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -82,13 +58,33 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & AESER == "Y") %>% - select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD) +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & AESER == "Y") |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AESER) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -101,7 +97,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -127,23 +123,23 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -151,7 +147,7 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% +lyt <- lyt |> analyze( "TRTEMFL", show_labels = "hidden", @@ -160,7 +156,7 @@ lyt <- lyt %>% extra_args_rr, list(label = "Subjects with >=1 SAE", NULL) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", @@ -168,20 +164,20 @@ lyt <- lyt %>% label_pos = "topleft", section_div = c(" "), nested = FALSE - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> analyze( "AEDECOD", afun = a_freq_j, extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ## Remove the N=xx column headers for the risk difference columns result <- remove_col_count(result) @@ -224,6 +220,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ + colwidth <- c(64, 21, 21, 21, 21, 31, 31) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae03c.R b/tests/testthat/source_code/tsfae03c.R new file mode 100644 index 00000000..5d649f76 --- /dev/null +++ b/tests/testthat/source_code/tsfae03c.R @@ -0,0 +1,228 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +# - Choose whether or not you want to present the risk difference columns (default=TRUE) +# - Choose which risk difference method you would like (default=Wald) +# - Define what the control treatment group is for your study (e.g Placebo) +# - Define how to create combined treatment columns (if required) +################################################################################ + +tblid <- "TSFAE03c" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +trtvar <- "TRT01A" +popfl <- "SAFFL" +combined_colspan_trt <- TRUE +risk_diff <- TRUE +rr_method <- "wald" +ctrl_grp <- "Placebo" + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +################################################################################ +# Process Data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) + +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & AESER == "Y" & AEREL == "RELATED") |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AEREL, AESER) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +if (risk_diff == TRUE) { + adsl$rrisk_header <- "Risk Difference (%) (95% CI)" + adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) +} + +# join data together +ae <- adae |> right_join(adsl, by = c("USUBJID")) + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +################################################################################ +# Define layout and build table: +################################################################################ + +extra_args_rr2 <- list( + denom = "n_altdf", + riskdiff = TRUE, + ref_path = ref_path, + method = "wald", + .stats = c("count_unique_fraction"), + .formats = c( + "rr_ci_3d" = jjcsformat_xx("xx.x (xx.x, xx.x)"), + "n_df" = "xx", + "aaa" = "xx" + ) +) +lyt <- basic_table( + top_level_section_div = " ", + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (risk_diff == TRUE) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels("Placebo") + ) +} + +lyt <- lyt |> + analyze( + "TRTEMFL", + afun = a_freq_j, + extra_args = append( + extra_args_rr2, + list(val = "Y", label = "Subjects with >= 1 related SAE") + ) + ) |> + split_rows_by( + "AEBODSYS", + split_label = "System Organ Class", + split_fun = trim_levels_in_group("AEDECOD"), + label_pos = "topleft", + section_div = c(" "), + nested = FALSE + ) |> + summarize_row_groups( + "AEBODSYS", + cfun = a_freq_j, + extra_args = extra_args_rr2 + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_rr2) |> + append_topleft(" Preferred Term, n (%)") + +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +# If there is no data remove top row and display "No data to display" text +if (length(adae$TRTEMFL) == 0) { + result <- safe_prune_table( + result, + prune_func = remove_rows(removerowtext = "Subjects with >= 1 related SAE") + ) +} + +######################################################################################### +# Post-Processing step to sort by descending count on chosen active treatment columns. +# Default is the last treatment (inc. Combined if applicable) under the active treatment +# spanning header (defaulted to colspan_trt variable). See function documentation for +# jj_complex_scorefun should your require a different sorting behavior. +######################################################################################### + +if (length(adae$TRTEMFL) != 0) { + result <- sort_at_path( + result, + c("root", "AEBODSYS"), + scorefun = jj_complex_scorefun() + ) + result <- sort_at_path( + result, + c("root", "AEBODSYS", "*", "AEDECOD"), + scorefun = jj_complex_scorefun() + ) +} + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21, 31, 30) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae04.R b/tests/testthat/source_code/tsfae03d.R similarity index 77% rename from tests/testthat/source_code/tsfae04.R rename to tests/testthat/source_code/tsfae03d.R index c416e74e..8c9303e3 100644 --- a/tests/testthat/source_code/tsfae04.R +++ b/tests/testthat/source_code/tsfae03d.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae04.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae04: TEAEs leading to treatment discontinuation -## Author: Johnson & Johnson Innovative Medicine -## Date: 19 Jan 2024 -## Input: ADSL, ADAE. -## Output: TSFAE04.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -43,7 +19,7 @@ library(junco) # - Define how to create combined treatment columns (if required) ################################################################################ -tblid <- "TSFAE04" +tblid <- "TSFAE03d" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -81,13 +57,33 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & AEACN == "DRUG WITHDRAWN") %>% - select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD) +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & AEACN == "DRUG WITHDRAWN") |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AEACN) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -100,7 +96,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -127,23 +123,23 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -151,16 +147,16 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% +lyt <- lyt |> analyze( "TRTEMFL", afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list(label = "Subjects with >=1 AE leading to discontinuation", NULL) + list(label = "Subjects with >=1 AE leading to treatment discontinuation", NULL) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", @@ -168,20 +164,20 @@ lyt <- lyt %>% label_pos = "topleft", section_div = c(" "), nested = FALSE - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> analyze( "AEDECOD", afun = a_freq_j, extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ## Remove the N=xx column headers for the risk difference columns result <- remove_col_count(result) @@ -191,7 +187,7 @@ if (length(adae$TRTEMFL) == 0) { result <- safe_prune_table( result, prune_func = remove_rows( - removerowtext = "Subjects with >=1 AE leading to discontinuation" + removerowtext = "Subjects with >=1 AE leading to treatment discontinuation" ) ) } @@ -226,6 +222,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 21, 29, 31) + +colwidth <- c(64, 21, 21, 21, 21, 29, 30) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae03e.R b/tests/testthat/source_code/tsfae03e.R new file mode 100644 index 00000000..7164898f --- /dev/null +++ b/tests/testthat/source_code/tsfae03e.R @@ -0,0 +1,228 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +# - Choose whether or not you want to present the risk difference columns (default=TRUE) +# - Choose which risk difference method you would like (default=Wald) +# - Define what the control treatment group is for your study (e.g Placebo) +# - Define how to create combined treatment columns (if required) +################################################################################ + +tblid <- "TSFAE03e" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +trtvar <- "TRT01A" +popfl <- "SAFFL" +combined_colspan_trt <- TRUE +risk_diff <- TRUE +rr_method <- "wald" +ctrl_grp <- "Placebo" + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +################################################################################ +# Process Data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) + +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & AETOXGRN >= 3) |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AETOXGRN) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +if (risk_diff == TRUE) { + adsl$rrisk_header <- "Risk Difference (%) (95% CI)" + adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) +} + +# join data together +ae <- adae |> right_join(adsl, by = c("USUBJID")) + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +################################################################################ +# Define layout and build table: +################################################################################ + +extra_args_rr2 <- list( + denom = "n_altdf", + riskdiff = TRUE, + ref_path = ref_path, + method = "wald", + .stats = c("count_unique_fraction"), + .formats = c( + "rr_ci_3d" = jjcsformat_xx("xx.x (xx.x, xx.x)"), + "n_df" = "xx", + "aaa" = "xx" + ) +) +lyt <- basic_table( + top_level_section_div = " ", + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (risk_diff == TRUE) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels("Placebo") + ) +} + +lyt <- lyt |> + analyze( + "TRTEMFL", + afun = a_freq_j, + extra_args = append( + extra_args_rr2, + list(val = "Y", label = "Subjects with >= 1 AEs >= Grade 3") + ) + ) |> + split_rows_by( + "AEBODSYS", + split_label = "System Organ Class", + split_fun = trim_levels_in_group("AEDECOD"), + label_pos = "topleft", + section_div = c(" "), + nested = FALSE + ) |> + summarize_row_groups( + "AEBODSYS", + cfun = a_freq_j, + extra_args = extra_args_rr2 + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_rr2) |> + append_topleft(" Preferred Term, n (%)") + +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +# If there is no data remove top row and display "No data to display" text +if (length(adae$TRTEMFL) == 0) { + result <- safe_prune_table( + result, + prune_func = remove_rows(removerowtext = "Subjects with >= 1 AEs >= Grade 3") + ) +} + +######################################################################################### +# Post-Processing step to sort by descending count on chosen active treatment columns. +# Default is the last treatment (inc. Combined if applicable) under the active treatment +# spanning header (defaulted to colspan_trt variable). See function documentation for +# jj_complex_scorefun should your require a different sorting behavior. +######################################################################################### + +if (length(adae$TRTEMFL) != 0) { + result <- sort_at_path( + result, + c("root", "AEBODSYS"), + scorefun = jj_complex_scorefun() + ) + result <- sort_at_path( + result, + c("root", "AEBODSYS", "*", "AEDECOD"), + scorefun = jj_complex_scorefun() + ) +} + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21, 33, 31) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae12.R b/tests/testthat/source_code/tsfae03f.R similarity index 73% rename from tests/testthat/source_code/tsfae12.R rename to tests/testthat/source_code/tsfae03f.R index 0ea10bc7..db39e32d 100644 --- a/tests/testthat/source_code/tsfae12.R +++ b/tests/testthat/source_code/tsfae03f.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae12.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae12: AE table by SOC/PT - TEAEs -## Author: Johnson & Johnson Innovative Medicine -## Date: 12 Dec 2023 -## Input: ADSL, ADAE. -## Output: TSFAE12.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -43,7 +19,7 @@ library(junco) # - Define how to create combined treatment columns (if required) ################################################################################ -tblid <- "TSFAE12" +tblid <- "TSFAE03f" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -82,24 +58,33 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% - filter( - TRTEMFL == "Y" & - !(AEACN %in% - c( - "", - NA_character_, - "DRUG WITHDRAWN", - "DOSE NOT CHANGED", - "UNKNOWN", - "NOT APPLICABLE" - )) - ) %>% - select(USUBJID, TRTEMFL, AEACN, AEBODSYS, AEDECOD) +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & toupper(AESCAT) == "INFUSION RELATED REACTION") |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AESCAT) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -112,7 +97,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -123,39 +108,45 @@ colspan_trt_map <- create_colspan_map( trt_var = trtvar ) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + ################################################################################ # Define layout and build table: ################################################################################ -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) -extra_args_rr <- list( - method = rr_method, +extra_args_rr2 <- list( + denom = "n_altdf", + riskdiff = TRUE, ref_path = ref_path, - .stats = c("count_unique_fraction") + method = "wald", + .stats = c("count_unique_fraction"), + .formats = c( + "rr_ci_3d" = jjcsformat_xx("xx.x (xx.x, xx.x)"), + "n_df" = "xx", + "aaa" = "xx" + ) ) - - lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -163,16 +154,15 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% +lyt <- lyt |> analyze( "TRTEMFL", afun = a_freq_j, - show_labels = "hidden", extra_args = append( - extra_args_rr, - list(label = "Subjects with >=1 AE", NULL) + extra_args_rr2, + list(val = "Y", label = "Subjects with >=1 infusion-related reactions") ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", @@ -180,20 +170,27 @@ lyt <- lyt %>% label_pos = "topleft", section_div = c(" "), nested = FALSE - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% + extra_args = extra_args_rr2 + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_rr2) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +# If there is no data remove top row and display "No data to display" text +if (length(adae$TRTEMFL) == 0) { + result <- safe_prune_table( + result, + prune_func = remove_rows(removerowtext = "Subjects with >=1 infusion-related reactions") + ) +} ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -215,17 +212,6 @@ if (length(adae$TRTEMFL) != 0) { ) } -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -# If there is no data remove top row and display "No data to display" text -if (length(adae$TRTEMFL) == 0) { - result <- safe_prune_table( - result, - prune_func = remove_rows(removerowtext = "Subjects with >=1 AE") - ) -} - ################################################################################ # Add titles and footnotes: ################################################################################ @@ -236,6 +222,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 21, 30, 31) + +colwidth <- c(64, 21, 21, 21, 21, 31, 29) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae04a.R b/tests/testthat/source_code/tsfae04a.R index cf32fbbd..b8adce3a 100644 --- a/tests/testthat/source_code/tsfae04a.R +++ b/tests/testthat/source_code/tsfae04a.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae04a.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae04a: AE table by SOC/PT and Subgroup - AEs leading to disc. of study trt. -## Author: Johnson & Johnson Innovative Medicine -## Date: 23 Feb 2024 -## Input: ADSL, ADAE. -## Output: TSFAE04a.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -36,7 +12,6 @@ library(junco) # - Define output ID and file location # - Define treatment variable used (default=TRT01A) # - Define population flag used (default=SAFFL) -# - subgroup variable required from ADSL, and subgroup text you want as a prefix to appear in the table, and any subgroup unit needed # - Choose whether or not you want to present a combined active treatment column (default=TRUE) # - Choose whether or not you want to present the risk difference columns (default=TRUE) # - Choose which risk difference method you would like (default=Wald) @@ -55,11 +30,6 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" - -subgrpvar <- "AGEGR1" -subgrptxt <- "Age Group" -subgrpunit <- "years" - combined_colspan_trt <- TRUE risk_diff <- TRUE rr_method <- "wald" @@ -88,29 +58,29 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> mutate( - subgrpdisplay = as.factor(paste0( - subgrptxt, - ": ", - !!as.name(subgrpvar), - " ", - subgrpunit - )) - ) %>% - select( - STUDYID, - USUBJID, - all_of(trtvar), - all_of(popfl), - all_of(subgrpvar), - subgrpdisplay - ) + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & AEACN == "DRUG WITHDRAWN") %>% - select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD) +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> + select(USUBJID, TRTEMFL, AEDECOD) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -123,7 +93,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- left_join(adsl, adae, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -139,22 +109,9 @@ colspan_trt_map <- create_colspan_map( ################################################################################ ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") - - extra_args_rr <- list( - denom = "n_altdf", - denom_by = "subgrpdisplay", - riskdiff = FALSE, - extrablankline = TRUE, - .stats = c("n_altdf") -) - -extra_args_rr2 <- list( - denom = "n_altdf", - denom_by = "subgrpdisplay", - riskdiff = TRUE, + method = rr_method, ref_path = ref_path, - method = "wald", .stats = c("count_unique_fraction") ) @@ -162,23 +119,23 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -186,59 +143,16 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% - split_rows_by( - "subgrpdisplay", - split_label = "", - split_fun = trim_levels_in_group("STUDYID"), - indent_mod = -1L, - section_div = c(" "), - page_by = TRUE - ) %>% # Set page_by = FALSE if you do not wish to start a new page after a new subgroup - summarize_row_groups( - "subgrpdisplay", - cfun = a_freq_j, - indent_mod = 0L, - extra_args = extra_args_rr - ) %>% - split_rows_by( - "TRTEMFL", - split_fun = keep_split_levels("Y"), - indent_mod = -1L, - section_div = c(" ") - ) %>% - summarize_row_groups( - "TRTEMFL", - cfun = a_freq_j, - indent_mod = 0L, - extra_args = append( - extra_args_rr2, - list( - label = "Subjects with >=1 AE leading to discontinuation", - extrablankline = TRUE - ) - ) - ) %>% - split_rows_by( - "AEBODSYS", - split_label = "System Organ Class", - split_fun = trim_levels_in_group("AEDECOD"), - label_pos = "topleft", - indent_mod = 0L, - section_div = c(" ") - ) %>% - summarize_row_groups( - "AEBODSYS", - cfun = a_freq_j, - extra_args = extra_args_rr2 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_rr2) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, ae, alt_counts_df = adsl) +lyt <- lyt |> + analyze( + "AEDECOD", + afun = a_freq_j, + extra_args = append(extra_args_rr, NULL), + indent_mod = 0L + ) |> + append_topleft("Preferred Term, n (%)") -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -248,18 +162,31 @@ result <- remove_col_count(result) ######################################################################################### if (length(adae$TRTEMFL) != 0) { - result <- sort_at_path( - result, - c("subgrpdisplay", "*", "TRTEMFL", "*", "AEBODSYS"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("subgrpdisplay", "*", "TRTEMFL", "*", "AEBODSYS", "*", "AEDECOD"), - scorefun = jj_complex_scorefun() + result <- sort_at_path(result, c("AEDECOD"), scorefun = jj_complex_scorefun()) + + ################################################################################ + # Prune table to only keep those that meet x% criteria for any treatment column + ################################################################################ + + more_than_x_percent <- has_fraction_in_any_col( + atleast = 0.05, + col_names = c( + "Active Study Agent.Xanomeline High Dose", + "Active Study Agent.Xanomeline Low Dose", + " .Placebo" + ) ) + + result <- safe_prune_table(result, keep_rows(more_than_x_percent)) } +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +## Remove any rogue null rows +result <- result |> + safe_prune_table(prune_func = keep_rows(keep_non_null_rows)) + ################################################################################ # Add titles and footnotes: ################################################################################ @@ -270,6 +197,6 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 19, 21, 21, 19, 32, 31) +colwidth <- c(52, 21, 21, 21, 19, 35, 31) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae06b.R b/tests/testthat/source_code/tsfae04b.R similarity index 77% rename from tests/testthat/source_code/tsfae06b.R rename to tests/testthat/source_code/tsfae04b.R index 23f29984..a74ea54a 100644 --- a/tests/testthat/source_code/tsfae06b.R +++ b/tests/testthat/source_code/tsfae04b.R @@ -1,28 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae06b.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae06b: AE table by PT - TEAEs≥[x]% in Drug-Treated Group and -## ≥[y]% More Often in Drug-Treated Group Than Placebo-Treated Group -## Author: Johnson & Johnson Innovative Medicine -## Date: 01 Feb 2024 -## Input: ADSL, ADAE. -## Output: TSFAE06b.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -44,7 +19,7 @@ library(junco) # - Define how to create combined treatment columns (if required) ################################################################################ -tblid <- "TSFAE06b" +tblid <- "TSFAE04b" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -83,12 +58,28 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> select(USUBJID, TRTEMFL, AEDECOD) adsl$colspan_trt <- factor( @@ -102,7 +93,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -128,23 +119,23 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -152,16 +143,16 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% +lyt <- lyt |> analyze( "AEDECOD", afun = a_freq_j, extra_args = append(extra_args_rr, NULL), indent_mod = 0L - ) %>% + ) |> append_topleft("Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -192,7 +183,7 @@ if (length(adae$TRTEMFL) != 0) { result <- remove_col_count(result) ## Remove any rogue null rows -result <- result %>% +result <- result |> safe_prune_table(prune_func = keep_rows(keep_non_null_rows)) ################################################################################ @@ -204,6 +195,7 @@ result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(59, 21, 21, 21, 19, 30, 29) + +colwidth <- c(43, 21, 21, 21, 19, 33, 28) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae11.R b/tests/testthat/source_code/tsfae04c.R similarity index 79% rename from tests/testthat/source_code/tsfae11.R rename to tests/testthat/source_code/tsfae04c.R index fb111545..0ab790b9 100644 --- a/tests/testthat/source_code/tsfae11.R +++ b/tests/testthat/source_code/tsfae04c.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae11.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae11: AE table by SOC/PT with >x% Frequency -## Author: Johnson & Johnson Innovative Medicine -## Date: 12 Dec 2023 -## Input: ADSL, ADAE. -## Output: TSFAE11.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -43,7 +19,7 @@ library(junco) # - Define how to create combined treatment columns (if required) ################################################################################ -tblid <- "TSFAE11" +tblid <- "TSFAE04c" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -81,12 +57,32 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD) adsl$colspan_trt <- factor( @@ -100,7 +96,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -127,23 +123,23 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -151,27 +147,27 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% +lyt <- lyt |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", split_fun = trim_levels_in_group("AEDECOD"), label_pos = "topleft", section_div = c(" ") - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> analyze( "AEDECOD", afun = a_freq_j, extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -220,6 +216,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 21, 31, 33) + +colwidth <- c(64, 21, 21, 21, 21, 35, 31) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae05.R b/tests/testthat/source_code/tsfae05.R index 6dbae34f..c2cddeeb 100644 --- a/tests/testthat/source_code/tsfae05.R +++ b/tests/testthat/source_code/tsfae05.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae05.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae05: AE table by SOC/PT - Related AEs -## Author: Johnson & Johnson Innovative Medicine -## Date: 19 Jan 2024 -## Input: ADSL, ADAE. -## Output: TSFAE05.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -37,9 +13,6 @@ library(junco) # - Define treatment variable used (default=TRT01A) # - Define population flag used (default=SAFFL) # - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) # - Define how to create combined treatment columns (if required) ################################################################################ @@ -51,13 +24,11 @@ tab_titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) - trtvar <- "TRT01A" popfl <- "SAFFL" +subjFilterText <- "Subjects with >=1 non-serious AE" + combined_colspan_trt <- TRUE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" if (combined_colspan_trt == TRUE) { # Set up levels and label for the required combined columns @@ -82,30 +53,45 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & AEREL == "RELATED") %>% - select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD) +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & AESER == "N") |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AESER) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), levels = c("Active Study Agent", " ") ) -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) -} - # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, - non_active_grp = ctrl_grp, + non_active_grp = "Placebo", non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", @@ -116,82 +102,64 @@ colspan_trt_map <- create_colspan_map( # Define layout and build table: ################################################################################ -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, +extra_args_1 <- list( + denom = "n_altdf", .stats = c("count_unique_fraction") ) -lyt <- basic_table( +lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - "TRT01A", - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) -} - -lyt <- lyt %>% +lyt <- lyt |> analyze( "TRTEMFL", afun = a_freq_j, show_labels = "hidden", extra_args = append( - extra_args_rr, - list(label = "Subjects with >=1 related AE", NULL) + extra_args_1, + list(label = subjFilterText, val = "Y") ) - ) %>% + ) |> split_rows_by( "AEBODSYS", + child_labels = "hidden", split_label = "System Organ Class", - split_fun = trim_levels_in_group("AEDECOD"), label_pos = "topleft", + split_fun = trim_levels_in_group("AEDECOD"), section_div = c(" "), - nested = FALSE - ) %>% + indent_mod = 0L + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% + extra_args = extra_args_1 + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") # If there is no data remove top row and display "No data to display" text if (length(adae$TRTEMFL) == 0) { result <- safe_prune_table( result, - prune_func = remove_rows(removerowtext = "Subjects with >=1 related AE") + prune_func = remove_rows(removerowtext = subjFilterText) ) } @@ -213,6 +181,18 @@ if (length(adae$TRTEMFL) != 0) { c("root", "AEBODSYS", "*", "AEDECOD"), scorefun = jj_complex_scorefun() ) + + ################################################################################ + # Prune table to only keep those that meet x% criteria, but top row is not subject to pruning + ################################################################################ + result <- safe_prune_table( + result, + prune_func = bspt_pruner( + fraction = 0.05, + keeprowtext = subjFilterText, + cols = c(trtvar) + ) + ) } ################################################################################ @@ -225,6 +205,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 19, 31, 31) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(64, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tsfae05a.R b/tests/testthat/source_code/tsfae05a.R deleted file mode 100644 index afdfdb74..00000000 --- a/tests/testthat/source_code/tsfae05a.R +++ /dev/null @@ -1,271 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae05a.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae05a: AE table by SOC/PT and Subgroup - Related AEs -## Author: Johnson & Johnson Innovative Medicine -## Date: 23 Feb 2024 -## Input: ADSL, ADAE. -## Output: TSFAE05a.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - subgroup variable required from ADSL, and subgroup text you want as a prefix to appear in the table, and any subgroup unit needed -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE05a" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" - -subgrpvar <- "AGEGR1" -subgrptxt <- "Age Group" -subgrpunit <- "years" - -combined_colspan_trt <- TRUE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - mutate( - subgrpdisplay = as.factor(paste0( - subgrptxt, - ": ", - !!as.name(subgrpvar), - " ", - subgrpunit - )) - ) %>% - select( - STUDYID, - USUBJID, - all_of(trtvar), - all_of(popfl), - all_of(subgrpvar), - subgrpdisplay - ) - -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & AEREL == "RELATED") %>% - select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) -} - -# join data together -ae <- left_join(adsl, adae, by = c("USUBJID")) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") - - -extra_args_rr <- list( - denom = "n_altdf", - denom_by = "subgrpdisplay", - riskdiff = FALSE, - extrablankline = TRUE, - .stats = c("n_altdf") -) - -extra_args_rr2 <- list( - denom = "n_altdf", - denom_by = "subgrpdisplay", - riskdiff = TRUE, - ref_path = ref_path, - method = "wald", - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) -} - -lyt <- lyt %>% - split_rows_by( - "subgrpdisplay", - split_label = "", - split_fun = trim_levels_in_group("STUDYID"), - indent_mod = -1L, - section_div = c(" "), - page_by = TRUE - ) %>% # Set page_by = FALSE if you do not wish to start a new page after a new subgroup - summarize_row_groups( - "subgrpdisplay", - cfun = a_freq_j, - indent_mod = 0L, - extra_args = extra_args_rr - ) %>% - split_rows_by( - "TRTEMFL", - split_fun = keep_split_levels("Y"), - indent_mod = -1L, - section_div = c(" ") - ) %>% - summarize_row_groups( - "TRTEMFL", - cfun = a_freq_j, - indent_mod = 0L, - extra_args = append( - extra_args_rr2, - list(label = "Subjects with >=1 related AE", extrablankline = TRUE) - ) - ) %>% - split_rows_by( - "AEBODSYS", - split_label = "System Organ Class", - split_fun = trim_levels_in_group("AEDECOD"), - label_pos = "topleft", - indent_mod = 0L, - section_div = c(" ") - ) %>% - summarize_row_groups( - "AEBODSYS", - cfun = a_freq_j, - extra_args = extra_args_rr2 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_rr2) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, ae, alt_counts_df = adsl) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (length(adae$TRTEMFL) != 0) { - # result <- sort_at_path( - # result, - # c("subgrpdisplay", "*", "TRTEMFL", "*", "AEBODSYS"), - # scorefun = jj_complex_scorefun() - # ) - result <- sort_at_path( - result, - c("subgrpdisplay", "*", "TRTEMFL", "*", "AEBODSYS", "*", "AEDECOD"), - scorefun = jj_complex_scorefun() - ) -} - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 19, 21, 21, 19, 32, 33) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae06a.R b/tests/testthat/source_code/tsfae06.R similarity index 65% rename from tests/testthat/source_code/tsfae06a.R rename to tests/testthat/source_code/tsfae06.R index 6d6c060a..ddb15286 100644 --- a/tests/testthat/source_code/tsfae06a.R +++ b/tests/testthat/source_code/tsfae06.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae06a.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae06a: AE table by PT - TEAEs≥[x]% in Drug-Treated Group -## Author: Johnson & Johnson Innovative Medicine -## Date: 04 Dec 2023 -## Input: ADSL, ADAE. -## Output: TSFAE06a.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -43,7 +19,7 @@ library(junco) # - Define how to create combined treatment columns (if required) ################################################################################ -tblid <- "TSFAE06a" +tblid <- "TSFAE06" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -82,13 +58,29 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% - select(USUBJID, TRTEMFL, AEDECOD) +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & AEOUT == "FATAL") |> + select(USUBJID, TRTEMFL, AEDECOD, AEOUT) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -101,7 +93,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -112,38 +104,45 @@ colspan_trt_map <- create_colspan_map( trt_var = trtvar ) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + ################################################################################ # Define layout and build table: ################################################################################ -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") -extra_args_rr <- list( - method = rr_method, +extra_args_rr2 <- list( + denom = "n_altdf", + riskdiff = TRUE, ref_path = ref_path, - .stats = c("count_unique_fraction") + method = "wald", + .stats = c("count_unique_fraction"), + .formats = c( + "rr_ci_3d" = jjcsformat_xx("xx.x (xx.x, xx.x)"), + "n_df" = "xx", + "aaa" = "xx" + ) ) - lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -151,16 +150,21 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% +lyt <- lyt |> analyze( "AEDECOD", afun = a_freq_j, - extra_args = append(extra_args_rr, NULL), - indent_mod = 0L - ) %>% + extra_args = extra_args_rr2 + ) |> append_topleft("Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +## Remove Null rows +result <- safe_prune_table(result) ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -170,31 +174,13 @@ result <- build_table(lyt, ae, alt_counts_df = adsl) ######################################################################################### if (length(adae$TRTEMFL) != 0) { - result <- sort_at_path(result, c("AEDECOD"), scorefun = jj_complex_scorefun()) - - ################################################################################ - # Prune table to only keep those that meet x% criteria for any treatment column - ################################################################################ - - more_than_x_percent <- has_fraction_in_any_col( - atleast = 0.05, - col_names = c( - "Active Study Agent.Xanomeline High Dose", - "Active Study Agent.Xanomeline Low Dose", - " .Placebo" - ) + result <- sort_at_path( + result, + c("root", "AEDECOD"), + scorefun = jj_complex_scorefun() ) - - result <- safe_prune_table(result, keep_rows(more_than_x_percent)) } -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -## Remove any rogue null rows -result <- result %>% - safe_prune_table(prune_func = keep_rows(keep_non_null_rows)) - ################################################################################ # Add titles and footnotes: ################################################################################ @@ -204,6 +190,8 @@ result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 19, 31, 33) + + +colwidth <- c(35, 5, 5, 5, 17, 29, 29) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae07a.R b/tests/testthat/source_code/tsfae07a.R index 77285dac..3099a7f8 100644 --- a/tests/testthat/source_code/tsfae07a.R +++ b/tests/testthat/source_code/tsfae07a.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae07a.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae07a: AE table of special interest - severity version -## Author: Johnson & Johnson Innovative Medicine -## Date: 27 Nov 2023 -## Input: ADSL, ADAE, ADLB (optional) -## Output: TSFAE07a.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -58,14 +34,14 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" -special_interest_var <- "CQ01NAM" -aerelvar <- "AEREL" -aeactionvar <- "AEACN" +special_interest_var <- "CQ02NAM" +special_interest_fl <- "AOCS02FL" combined_colspan_trt <- TRUE risk_diff <- TRUE rr_method <- "wald" ctrl_grp <- "Placebo" +combination_trt <- FALSE # Provide whether this is a combination treatments study if (combined_colspan_trt == TRUE) { # Set up levels and label for the required combined columns @@ -86,6 +62,17 @@ if (combined_colspan_trt == TRUE) { mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) } +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc +} else if (!combination_trt) { + comb_trtvars <- trtvar + comb_relvars <- "AEREL" +} + # Optional lab section parameters labsection <- TRUE lab_params <- c("AST", "ALT") @@ -97,9 +84,19 @@ lab_vals <- c("2,3", "2,3") # Note both character or numeric values can be enclo # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) lbdata <- NULL @@ -108,31 +105,31 @@ if (labsection == TRUE) { for (i in 1:length(lab_params)) { filter_val <- unlist(strsplit(lab_vals[[i]], ",")) - adlb <- adlb_jnj %>% + adlb <- adlb_jnj |> filter( TRTEMFL == "Y" & PARAMCD == lab_params[[i]] & !!rlang::sym(lab_var[[i]]) %in% filter_val - ) %>% - mutate(criteria = lab_labels[[i]]) %>% + ) |> + mutate(criteria = lab_labels[[i]]) |> select(USUBJID, TRTEMFL, PARAMCD, all_of(lab_var[[i]]), criteria) lbdata <- bind_rows(adlb, lbdata) } - adlb <- lbdata %>% - group_by(USUBJID, TRTEMFL, PARAMCD, criteria) %>% - slice(1) %>% + adlb <- lbdata |> + group_by(USUBJID, TRTEMFL, PARAMCD, criteria) |> + slice(1) |> ungroup() # Create flag variable for each parameter that met the condition to merge back onto adsl # Overall row - adlbparamall <- adlb %>% - filter(PARAMCD %in% lab_params) %>% - mutate(lab_flag = "Y") %>% - group_by(USUBJID) %>% - slice(1) %>% - ungroup() %>% + adlbparamall <- adlb |> + filter(PARAMCD %in% lab_params) |> + mutate(lab_flag = "Y") |> + group_by(USUBJID) |> + slice(1) |> + ungroup() |> select(USUBJID, lab_flag) adsl <- left_join(adsl, adlbparamall, by = c("USUBJID")) @@ -141,30 +138,47 @@ if (labsection == TRUE) { for (i in 1:length(lab_params)) { flagvar <- paste0("lab_flag", i) - adlbparam <- adlb %>% - filter(PARAMCD == lab_params[[i]] & criteria == lab_labels[[i]]) %>% - mutate(!!flagvar := lab_labels[[i]]) %>% - group_by(USUBJID) %>% - slice(1) %>% - ungroup() %>% + adlbparam <- adlb |> + filter(PARAMCD == lab_params[[i]] & criteria == lab_labels[[i]]) |> + mutate(!!flagvar := lab_labels[[i]]) |> + group_by(USUBJID) |> + slice(1) |> + ungroup() |> select(USUBJID, all_of(flagvar)) adsl <- left_join(adsl, adlbparam, by = c("USUBJID")) } } -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & !is.na(!!rlang::sym(special_interest_var))) %>% +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & !is.na(!!rlang::sym(special_interest_var))) |> select( USUBJID, TRTEMFL, - AEBODSYS, + all_of(comb_trtvars), AEDECOD, AESEV, + ASEVN, all_of(special_interest_var), + all_of(special_interest_fl), AESER, AEOUT, - all_of(aeactionvar), - all_of(aerelvar) + all_of(comb_relvars), + AESDTH, + AESLIFE, + AESHOSP, + AESDISAB, + AESCONG, + AESMIE, + TRDISCFL + ) |> + select( + -any_of(trtvar) ) adsl$colspan_trt <- factor( @@ -178,25 +192,45 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> inner_join(adsl, by = c("USUBJID")) # Keep only maximum severity for the particular AESI -ae <- ae %>% + +ae <- ae |> + group_by(USUBJID, .data[[special_interest_var]]) |> + mutate(ASEV = ASEVN[which(.data[[special_interest_fl]] == "Y")][1]) |> + ungroup() |> + mutate(ASEV = ifelse(is.na(ASEV), "Missing", as.character(ASEV))) |> mutate( ASEV = factor( - ifelse(is.na(AESEV), "Missing", as.character(AESEV)), - levels = c("Severe", "Moderate", "Mild", "Missing") + ASEV, + levels = c( + "3", + "2", + "1", + "Missing" + ), + labels = c( + "Severe", + "Moderate", + "Mild", + "Missing" + ) ), - rowhead = "Maximum severity" - ) %>% - arrange(USUBJID, special_interest_var, ASEV) %>% - group_by(USUBJID, .data[[special_interest_var]]) %>% - slice(1) %>% - ungroup() + rowhead = "Worst severity" + ) + # Remove Missing as a level since not required in table levels(ae$ASEV)[levels(ae$ASEV) == "Missing"] <- NA + +if (combination_trt) { + comb_rel_ae_labels <- paste(sapply(comb_trtvars, \(x) unique(adae[[x]])[1]), "related~[super b]") +} else if (!combination_trt) { + comb_rel_ae_labels <- "Related~[super b]" +} + colspan_trt_map <- create_colspan_map( adsl, non_active_grp = ctrl_grp, @@ -221,23 +255,23 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -245,7 +279,7 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% +lyt <- lyt |> split_rows_by( special_interest_var, split_label = "", @@ -253,95 +287,147 @@ lyt <- lyt %>% label_pos = "topleft", indent_mod = 0, section_div = c(" ") - ) %>% + ) |> summarize_row_groups( special_interest_var, cfun = a_freq_j, extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> analyze( "AEDECOD", - var_labels = "Preferred Term", + var_labels = "Preferred term", afun = a_freq_j, indent_mod = 0, show_labels = "visible", extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> split_rows_by( "rowhead", split_label = "", - # ,split_fun = trim_levels_in_group("ASEV") label_pos = "topleft", indent_mod = 0, section_div = c(" ") - ) %>% + ) |> analyze( "ASEV", afun = a_freq_j, indent_mod = 0, extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> split_rows_by( "AESER", split_fun = keep_split_levels("Y"), section_div = c(" ") - ) %>% + ) |> summarize_row_groups( "AESER", cfun = a_freq_j, - extra_args = append(extra_args_rr, list(label = "Serious", NULL)) - ) %>% + extra_args = append(extra_args_rr, list(label = "SAE classification~[super a]", NULL)) + ) |> analyze( - "AEOUT", + "AESDTH", afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list(label = "Deaths", val = "FATAL", NULL) + list(label = "Death", val = "Y", NULL) ) - ) %>% + ) |> analyze( - aeactionvar, + "AESLIFE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Life-threatening", val = "Y", NULL) + ) + ) |> + analyze( + "AESHOSP", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Requires or prolongs hospitalization", val = "Y", NULL) + ) + ) |> + analyze( + "AESDISAB", afun = a_freq_j, show_labels = "hidden", - nested = FALSE, extra_args = append( extra_args_rr, list( - label = "Resulting in treatment discontinuation", - val = "DRUG WITHDRAWN", + label = "Persistent or significant disability/incapacity", + val = "Y", NULL ) ) - ) %>% + ) |> + analyze( + "AESCONG", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Congenital anomaly or birth defect", val = "Y", NULL) + ) + ) |> analyze( - aerelvar, + "AESMIE", afun = a_freq_j, show_labels = "hidden", - nested = FALSE, extra_args = append( extra_args_rr, - list(label = "Related~[super a]", val = "RELATED", NULL) + list(label = "Other medically important event", val = "Y", NULL) + ) + ) |> + analyze( + "TRDISCFL", + afun = a_freq_j, + show_labels = "hidden", + at_sibling = "AESER", + extra_args = append( + extra_args_rr, + list( + label = "Leading to permanent discontinuation of study treatment", + val = "Y", + NULL + ) ) ) +for (i in seq_along(comb_relvars)) { + lyt <- lyt |> + analyze( + comb_relvars[i], + afun = a_freq_j, + show_labels = "hidden", + at_sibling = if (i == 1) "TRDISCFL" else NULL, + extra_args = append( + extra_args_rr, + list(label = comb_rel_ae_labels[i], val = toupper("Related"), NULL) + ) + ) +} + if (labsection == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> analyze( "lab_flag", afun = a_freq_j, show_labels = "hidden", - nested = FALSE, + at_sibling = comb_relvars[1], extra_args = append( extra_args_rr, - list(label = "Laboratory assessment~[super b]", NULL) + list(label = "Laboratory assessment~[super c]", NULL) ) ) for (i in 1:length(lab_params)) { aflagvar <- paste0("lab_flag", i) - lyt <- lyt %>% + lyt <- lyt |> analyze( aflagvar, afun = a_freq_j, @@ -353,17 +439,25 @@ if (labsection == TRUE) { } } -lyt <- lyt %>% - append_topleft("AESI Assessment, n (%)") +lyt <- lyt |> + append_topleft("AE of Interest Assessment, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ## Remove the N=xx column headers for the risk difference columns result <- remove_col_count(result) ## Remove any rogue null rows -result <- result %>% - safe_prune_table(prune_func = keep_rows(keep_non_null_rows)) +result <- suppressWarnings(safe_prune_table( + result, + prune_func = count_pruner( + cat_exclude = c( + "Mild", + "Moderate", + "Severe" + ) + ) +)) ################################################################################ # Add titles and footnotes: @@ -375,6 +469,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 23, 21, 31, 35) + +colwidth <- c(64, 21, 21, 21, 21, 33, 30) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae07b.R b/tests/testthat/source_code/tsfae07b.R index b6fa0f62..0aa3b4fe 100644 --- a/tests/testthat/source_code/tsfae07b.R +++ b/tests/testthat/source_code/tsfae07b.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae07b.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae07b: AE table of special interest - toxicity version -## Author: Johnson & Johnson Innovative Medicine -## Date: 16 Feb 2024 -## Input: ADSL, ADAE, ADLB (optional) -## Output: TSFAE07b.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -58,14 +34,14 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" -special_interest_var <- "CQ01NAM" -aerelvar <- "AEREL" -aeactionvar <- "AEACN" +special_interest_var <- "CQ02NAM" +special_interest_fl <- "AOCT02FL" combined_colspan_trt <- TRUE risk_diff <- TRUE rr_method <- "wald" ctrl_grp <- "Placebo" +combination_trt <- FALSE # Provide whether this is a combination treatments study if (combined_colspan_trt == TRUE) { # Set up levels and label for the required combined columns @@ -86,6 +62,17 @@ if (combined_colspan_trt == TRUE) { mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) } +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc +} else if (!combination_trt) { + comb_trtvars <- trtvar + comb_relvars <- "AEREL" +} + # Optional lab section parameters labsection <- TRUE lab_params <- c("AST", "ALT") @@ -97,9 +84,20 @@ lab_vals <- c("2,3", "2,3") # Note both character or numeric values can be enclo # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + lbdata <- NULL @@ -108,31 +106,31 @@ if (labsection == TRUE) { for (i in 1:length(lab_params)) { filter_val <- unlist(strsplit(lab_vals[[i]], ",")) - adlb <- adlb_jnj %>% + adlb <- adlb_jnj |> filter( TRTEMFL == "Y" & PARAMCD == lab_params[[i]] & !!rlang::sym(lab_var[[i]]) %in% filter_val - ) %>% - mutate(criteria = lab_labels[[i]]) %>% + ) |> + mutate(criteria = lab_labels[[i]]) |> select(USUBJID, TRTEMFL, PARAMCD, all_of(lab_var[[i]]), criteria) lbdata <- bind_rows(adlb, lbdata) } - adlb <- lbdata %>% - group_by(USUBJID, TRTEMFL, PARAMCD, criteria) %>% - slice(1) %>% + adlb <- lbdata |> + group_by(USUBJID, TRTEMFL, PARAMCD, criteria) |> + slice(1) |> ungroup() # Create flag variable for each parameter that met the condition to merge back onto adsl # Overall row - adlbparamall <- adlb %>% - filter(PARAMCD %in% lab_params) %>% - mutate(lab_flag = "Y") %>% - group_by(USUBJID) %>% - slice(1) %>% - ungroup() %>% + adlbparamall <- adlb |> + filter(PARAMCD %in% lab_params) |> + mutate(lab_flag = "Y") |> + group_by(USUBJID) |> + slice(1) |> + ungroup() |> select(USUBJID, lab_flag) adsl <- left_join(adsl, adlbparamall, by = c("USUBJID")) @@ -141,30 +139,47 @@ if (labsection == TRUE) { for (i in 1:length(lab_params)) { flagvar <- paste0("lab_flag", i) - adlbparam <- adlb %>% - filter(PARAMCD == lab_params[[i]] & criteria == lab_labels[[i]]) %>% - mutate(!!flagvar := lab_labels[[i]]) %>% - group_by(USUBJID) %>% - slice(1) %>% - ungroup() %>% + adlbparam <- adlb |> + filter(PARAMCD == lab_params[[i]] & criteria == lab_labels[[i]]) |> + mutate(!!flagvar := lab_labels[[i]]) |> + group_by(USUBJID) |> + slice(1) |> + ungroup() |> select(USUBJID, all_of(flagvar)) adsl <- left_join(adsl, adlbparam, by = c("USUBJID")) } } -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & !is.na(!!rlang::sym(special_interest_var))) %>% +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & !is.na(!!rlang::sym(special_interest_var))) |> select( USUBJID, TRTEMFL, - AEBODSYS, + all_of(comb_trtvars), AEDECOD, AETOXGR, + AETOXGRN, all_of(special_interest_var), + all_of(special_interest_fl), AESER, AEOUT, - all_of(aeactionvar), - all_of(aerelvar) + all_of(comb_relvars), + AESDTH, + AESLIFE, + AESHOSP, + AESDISAB, + AESCONG, + AESMIE, + TRDISCFL + ) |> + select( + -any_of(trtvar) ) adsl$colspan_trt <- factor( @@ -178,17 +193,17 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> inner_join(adsl, by = c("USUBJID")) # Keep only maximum toxicity for the particular AESI -ae <- ae %>% +ae <- ae |> + group_by(USUBJID, .data[[special_interest_var]]) |> + mutate(ATOXGR = AETOXGRN[which(.data[[special_interest_fl]] == "Y")][1]) |> + ungroup() |> + mutate(ATOXGR = ifelse(is.na(ATOXGR), "Missing", paste("Grade", ATOXGR))) |> mutate( ATOXGR = factor( - ifelse( - is.na(AETOXGR), - "Missing", - as.character(paste0("Grade ", AETOXGR)) - ), + ATOXGR, levels = c( "Grade 5", "Grade 4", @@ -198,16 +213,18 @@ ae <- ae %>% "Missing" ) ), - rowhead = "Maximum toxicity" - ) %>% - arrange(USUBJID, special_interest_var, ATOXGR) %>% - group_by(USUBJID, .data[[special_interest_var]]) %>% - slice(1) %>% - ungroup() + rowhead = "Worst toxicity" + ) # Remove Missing as a level since not required in table levels(ae$ATOXGR)[levels(ae$ATOXGR) == "Missing"] <- NA +if (combination_trt) { + comb_rel_ae_labels <- paste(sapply(comb_trtvars, \(x) unique(adae[[x]])[1]), "related~[super b]") +} else if (!combination_trt) { + comb_rel_ae_labels <- "Related~[super b]" +} + colspan_trt_map <- create_colspan_map( adsl, non_active_grp = ctrl_grp, @@ -232,23 +249,23 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -256,7 +273,7 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% +lyt <- lyt |> split_rows_by( special_interest_var, split_label = "", @@ -264,95 +281,144 @@ lyt <- lyt %>% label_pos = "topleft", indent_mod = 0, section_div = c(" ") - ) %>% + ) |> summarize_row_groups( special_interest_var, cfun = a_freq_j, extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> analyze( "AEDECOD", - var_labels = "Preferred Term", + var_labels = "Preferred term", afun = a_freq_j, indent_mod = 0, show_labels = "visible", extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> split_rows_by( "rowhead", split_label = "", - # ,split_fun = trim_levels_in_group("ATOXGR") label_pos = "topleft", indent_mod = 0, section_div = c(" ") - ) %>% + ) |> analyze( "ATOXGR", afun = a_freq_j, indent_mod = 0, extra_args = append(extra_args_rr, NULL) - ) %>% + ) |> split_rows_by( "AESER", split_fun = keep_split_levels("Y"), section_div = " " - ) %>% + ) |> summarize_row_groups( "AESER", cfun = a_freq_j, - extra_args = append(extra_args_rr, list(label = "Serious", NULL)) - ) %>% + extra_args = append(extra_args_rr, list(label = "SAE classification~[super a]", NULL)) + ) |> + analyze( + "AESDTH", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Death", val = "Y", NULL) + ) + ) |> + analyze( + "AESLIFE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Life-threatening", val = "Y", NULL) + ) + ) |> analyze( - "AEOUT", + "AESHOSP", afun = a_freq_j, show_labels = "hidden", extra_args = append( extra_args_rr, - list(label = "Deaths", val = "FATAL", NULL) + list(label = "Requires or prolongs hospitalization", val = "Y", NULL) ) - ) %>% + ) |> analyze( - aeactionvar, + "AESDISAB", afun = a_freq_j, show_labels = "hidden", - nested = FALSE, extra_args = append( extra_args_rr, list( - label = "Resulting in treatment discontinuation", - val = "DRUG WITHDRAWN", + label = "Persistent or significant disability/incapacity", + val = "Y", NULL ) ) - ) %>% + ) |> analyze( - aerelvar, + "AESCONG", afun = a_freq_j, show_labels = "hidden", - nested = FALSE, extra_args = append( extra_args_rr, - list(label = "Related~[super a]", val = "RELATED", NULL) + list(label = "Congenital anomaly or birth defect", val = "Y", NULL) + ) + ) |> + analyze( + "AESMIE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append(extra_args_rr, list(label = "Other medically important event", val = "Y", NULL)) + ) |> + analyze( + "TRDISCFL", + afun = a_freq_j, + show_labels = "hidden", + at_sibling = "AESER", + extra_args = append( + extra_args_rr, + list( + label = "Leading to permanent discontinuation of study treatment", + val = "Y", + NULL + ) ) ) +for (i in seq_along(comb_relvars)) { + lyt <- lyt |> + analyze( + comb_relvars[i], + afun = a_freq_j, + show_labels = "hidden", + at_sibling = if (i == 1) "TRDISCFL" else NULL, + extra_args = append( + extra_args_rr, + list(label = comb_rel_ae_labels[i], val = toupper("Related"), NULL) + ) + ) +} + if (labsection == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> analyze( "lab_flag", afun = a_freq_j, show_labels = "hidden", - nested = FALSE, + at_sibling = comb_relvars[1], extra_args = append( extra_args_rr, - list(label = "Laboratory assessment~[super b]", NULL) + list(label = "Laboratory assessment~[super c]", NULL) ) ) for (i in 1:length(lab_params)) { aflagvar <- paste0("lab_flag", i) - lyt <- lyt %>% + lyt <- lyt |> analyze( aflagvar, afun = a_freq_j, @@ -364,17 +430,27 @@ if (labsection == TRUE) { } } -lyt <- lyt %>% - append_topleft("AESI Assessment, n (%)") +lyt <- lyt |> + append_topleft("AE of Interest Assessment, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ## Remove the N=xx column headers for the risk difference columns result <- remove_col_count(result) ## Remove any rogue null rows -result <- result %>% - safe_prune_table(prune_func = keep_rows(keep_non_null_rows)) +result <- suppressWarnings(safe_prune_table( + result, + prune_func = count_pruner( + cat_exclude = c( + "Grade 1", + "Grade 2", + "Grade 3", + "Grade 4", + "Grade 5" + ) + ) +)) ################################################################################ # Add titles and footnotes: @@ -386,6 +462,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 23, 21, 31, 35) + +colwidth <- c(64, 21, 21, 21, 21, 33, 29) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae14.R b/tests/testthat/source_code/tsfae07c.R similarity index 56% rename from tests/testthat/source_code/tsfae14.R rename to tests/testthat/source_code/tsfae07c.R index be86bb39..aceb0f63 100644 --- a/tests/testthat/source_code/tsfae14.R +++ b/tests/testthat/source_code/tsfae07c.R @@ -1,28 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae14.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Serious Adverse Events -## by Organ System and OCMQ (Narrow) -## Author: Johnson & Johnson Innovative Medicine -## Date: 2025-07-21 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE14.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored cpct_relrisk_fact to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -44,7 +19,7 @@ library(junco) # - Define how to create combined treatment columns (if required) ################################################################################ -tblid <- "TSFAE14" +tblid <- "TSFAE07c" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -52,8 +27,10 @@ tab_titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) + trtvar <- "TRT01A" popfl <- "SAFFL" +special_interest_var <- c("CQ01NAM", "CQ02NAM", "CQ03NAM") combined_colspan_trt <- TRUE risk_diff <- TRUE rr_method <- "wald" @@ -82,13 +59,23 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adaeocmq_jnj %>% - filter(TRTEMFL == "Y" & AESER == "Y" & OCMQCLSS == "Narrow") %>% - select(USUBJID, TRTEMFL, OCMQSOC, OCMQNAM) +adae <- adae_jnj |> + filter(TRTEMFL == "Y" & if_any(all_of(special_interest_var), ~ !is.na(.))) |> + select(USUBJID, TRTEMFL, all_of(special_interest_var)) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -101,7 +88,7 @@ if (risk_diff == TRUE) { } # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -112,38 +99,45 @@ colspan_trt_map <- create_colspan_map( trt_var = trtvar ) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + ################################################################################ # Define layout and build table: ################################################################################ -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") -extra_args_rr <- list( - method = rr_method, +extra_args_rr2 <- list( + denom = "n_altdf", + riskdiff = TRUE, ref_path = ref_path, - .stats = c("count_unique_fraction") + method = "wald", + .stats = c("count_unique_fraction"), + .formats = c( + "rr_ci_3d" = jjcsformat_xx("xx.x (xx.x, xx.x)"), + "n_df" = "xx", + "aaa" = "xx" + ) ) - lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -151,57 +145,21 @@ if (risk_diff == TRUE) { ) } -lyt <- lyt %>% - split_rows_by( - "OCMQSOC", - split_label = "Organ System~[super a]", - split_fun = trim_levels_in_group("OCMQNAM"), - label_pos = "topleft", - section_div = c(" "), - nested = FALSE - ) %>% - summarize_row_groups( - "OCMQSOC", - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% +lyt <- lyt |> analyze( - "OCMQNAM", + special_interest_var, afun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - append_topleft(" OCMQ (Narrow), n (%)") + section_div = " ", + show_labels = "hidden", + extra_args = extra_args_rr2 + ) |> + append_topleft("AE of Interest Assessment, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ## Remove the N=xx column headers for the risk difference columns result <- remove_col_count(result) -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - result <- sort_at_path( - result, - c("root", "OCMQSOC"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("root", "OCMQSOC", "*", "OCMQNAM"), - scorefun = jj_complex_scorefun() - ) -} - ################################################################################ # Add titles and footnotes: ################################################################################ @@ -212,6 +170,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 21, 31, 31) + +colwidth <- c(29, 21, 21, 21, 21, 28, 28) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae07d.R b/tests/testthat/source_code/tsfae07d.R new file mode 100644 index 00000000..489f3551 --- /dev/null +++ b/tests/testthat/source_code/tsfae07d.R @@ -0,0 +1,472 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Define the customized query variable (CQzzNAM) for the AEs of special interest +# - Define the ADaM Variable to choose the AE related variable(s) and Action taken variable(s) +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +# - Choose whether or not you want to present the risk difference columns (default=TRUE) +# - Choose which risk difference method you would like (default=Wald) +# - Define what the control treatment group is for your study (e.g Placebo) +# - Define how to create combined treatment columns (if required) +# - Define lab parameters that are required for the optional section of the table +################################################################################ + +tblid <- "TSFAE07d" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +trtvar <- "TRT01A" +popfl <- "SAFFL" + +interest_var <- "CQ02NAM" # Change to the variable needed for analysis +interest_fl <- "AOCS02FL" # Change to the variable needed for analysis + +combined_colspan_trt <- TRUE +risk_diff <- TRUE +rr_method <- "wald" +ctrl_grp <- "Placebo" +combination_trt <- FALSE # Provide whether this is a combination treatments study + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc +} else if (!combination_trt) { + comb_trtvars <- trtvar + comb_relvars <- "AEREL" +} + +# Optional lab section parameters +labsection <- TRUE +lab_params <- c("AST", "ALT") +lab_labels <- c("AST>5xULN", "ALT>5xULN") +lab_var <- c("MCRIT1MN", "MCRIT1MN") +lab_vals <- c("2,3", "2,3") # Note both character or numeric values can be enclosed within in one set of double quotations here + +################################################################################ +# Process Data: +################################################################################ + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + +lbdata <- NULL + +# Optional lab section +if (labsection == TRUE) { + for (i in 1:length(lab_params)) { + filter_val <- unlist(strsplit(lab_vals[[i]], ",")) + + adlb <- adlb_jnj |> + filter( + TRTEMFL == "Y" & + PARAMCD == lab_params[[i]] & + !!rlang::sym(lab_var[[i]]) %in% filter_val + ) |> + mutate(criteria = lab_labels[[i]]) |> + select(USUBJID, TRTEMFL, PARAMCD, all_of(lab_var[[i]]), criteria) + + lbdata <- bind_rows(adlb, lbdata) + } + + adlb <- lbdata |> + group_by(USUBJID, TRTEMFL, PARAMCD, criteria) |> + slice(1) |> + ungroup() + + # Create flag variable for each parameter that met the condition to merge back onto adsl + # Overall row + adlbparamall <- adlb |> + filter(PARAMCD %in% lab_params) |> + mutate(lab_flag = "Y") |> + group_by(USUBJID) |> + slice(1) |> + ungroup() |> + select(USUBJID, lab_flag) + + adsl <- left_join(adsl, adlbparamall, by = c("USUBJID")) + + # Loop through each parameter that the user has specified and merge flag variable onto adsl + for (i in 1:length(lab_params)) { + flagvar <- paste0("lab_flag", i) + + adlbparam <- adlb |> + filter(PARAMCD == lab_params[[i]] & criteria == lab_labels[[i]]) |> + mutate(!!flagvar := lab_labels[[i]]) |> + group_by(USUBJID) |> + slice(1) |> + ungroup() |> + select(USUBJID, all_of(flagvar)) + adsl <- left_join(adsl, adlbparam, by = c("USUBJID")) + } +} + +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & !is.na(!!rlang::sym(interest_var))) |> + select( + USUBJID, + TRTEMFL, + all_of(comb_trtvars), + AEDECOD, + AESEV, + ASEVN, + all_of(interest_var), + all_of(interest_fl), + AESER, + AEOUT, + all_of(comb_relvars), + AESDTH, + AESLIFE, + AESHOSP, + AESDISAB, + AESCONG, + AESMIE, + TRDISCFL + ) |> + select( + -any_of(trtvar) + ) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +if (risk_diff == TRUE) { + adsl$rrisk_header <- "Risk Difference (%) (95% CI)" + adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) +} + +# join data together +ae <- adae |> inner_join(adsl, by = c("USUBJID")) + +# Keep only maximum severity for the particular AESI +ae <- ae |> + group_by(USUBJID, .data[[interest_var]]) |> + mutate(ASEV = ASEVN[which(.data[[interest_fl]] == "Y")][1]) |> + ungroup() |> + mutate(ASEV = ifelse(is.na(ASEV), "Missing", as.character(ASEV))) |> + mutate( + ASEV = factor( + ASEV, + levels = c( + "3", + "2", + "1", + "Missing" + ), + labels = c( + "Severe", + "Moderate", + "Mild", + "Missing" + ) + ), + rowhead = "Worst severity" + ) + +# Remove Missing as a level since not required in table +levels(ae$ASEV)[levels(ae$ASEV) == "Missing"] <- NA + +if (combination_trt) { + comb_rel_ae_labels <- paste(sapply(comb_trtvars, \(x) unique(adae[[x]])[1]), "related~[super b]") +} else if (!combination_trt) { + comb_rel_ae_labels <- "Related~[super b]" +} + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +################################################################################ +# Define layout and build table: +################################################################################ + +ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") +extra_args_rr <- list( + method = rr_method, + ref_path = ref_path, + .stats = c("count_unique_fraction") +) + +lyt <- basic_table( + top_level_section_div = " ", + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (risk_diff == TRUE) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels("Placebo") + ) +} + +lyt <- lyt |> + split_rows_by( + interest_var, + split_label = "", + split_fun = trim_levels_in_group("AEDECOD"), + label_pos = "topleft", + indent_mod = 0, + section_div = c(" ") + ) |> + summarize_row_groups( + interest_var, + cfun = a_freq_j, + extra_args = append(extra_args_rr, NULL) + ) |> + analyze( + "AEDECOD", + var_labels = "Preferred term", + afun = a_freq_j, + indent_mod = 0, + show_labels = "visible", + extra_args = append(extra_args_rr, NULL) + ) |> + split_rows_by( + "rowhead", + split_label = "", + label_pos = "topleft", + indent_mod = 0, + section_div = c(" ") + ) |> + analyze( + "ASEV", + afun = a_freq_j, + indent_mod = 0, + extra_args = append(extra_args_rr, NULL) + ) |> + split_rows_by( + "AESER", + split_fun = keep_split_levels("Y"), + section_div = c(" ") + ) |> + summarize_row_groups( + "AESER", + cfun = a_freq_j, + extra_args = append(extra_args_rr, list(label = "SAE classification~[super a]", NULL)) + ) |> + analyze( + "AESDTH", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Death", val = "Y", NULL) + ) + ) |> + analyze( + "AESLIFE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Life-threatening", val = "Y", NULL) + ) + ) |> + analyze( + "AESHOSP", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Requires or prolongs hospitalization", val = "Y", NULL) + ) + ) |> + analyze( + "AESDISAB", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list( + label = "Persistent or significant disability/incapacity", + val = "Y", + NULL + ) + ) + ) |> + analyze( + "AESCONG", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Congenital anomaly or birth defect", val = "Y", NULL) + ) + ) |> + analyze( + "AESMIE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Other medically important event", val = "Y", NULL) + ) + ) |> + analyze( + "TRDISCFL", + afun = a_freq_j, + show_labels = "hidden", + at_sibling = "AESER", + extra_args = append( + extra_args_rr, + list( + label = "Leading to permanent discontinuation of study treatment", + val = "Y", + NULL + ) + ) + ) + +for (i in seq_along(comb_relvars)) { + lyt <- lyt |> + analyze( + comb_relvars[i], + afun = a_freq_j, + show_labels = "hidden", + at_sibling = if (i == 1) "TRDISCFL" else NULL, + extra_args = append( + extra_args_rr, + list(label = comb_rel_ae_labels[i], val = toupper("Related"), NULL) + ) + ) +} + +if (labsection == TRUE) { + lyt <- lyt |> + analyze( + "lab_flag", + afun = a_freq_j, + show_labels = "hidden", + at_sibling = comb_relvars[1], + extra_args = append( + extra_args_rr, + list(label = "Laboratory assessment~[super c]", NULL) + ) + ) + + for (i in 1:length(lab_params)) { + aflagvar <- paste0("lab_flag", i) + + lyt <- lyt |> + analyze( + aflagvar, + afun = a_freq_j, + indent_mod = 1, + show_labels = "hidden", + nested = TRUE, + extra_args = append(extra_args_rr, NULL) + ) + } +} + +lyt <- lyt |> + append_topleft("AE of Interest Assessment, n (%)") + +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +## Remove any rogue null rows +result <- suppressWarnings(safe_prune_table( + result, + prune_func = count_pruner( + cat_exclude = c( + "Mild", + "Moderate", + "Severe" + ) + ) +)) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21, 33, 30) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae07e.R b/tests/testthat/source_code/tsfae07e.R new file mode 100644 index 00000000..a2f1af3a --- /dev/null +++ b/tests/testthat/source_code/tsfae07e.R @@ -0,0 +1,468 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Define the customized query variable (CQzzNAM) for the AEs of special interest +# - Define the ADaM Variable to choose the AE related variable(s) and Action taken variable(s) +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +# - Choose whether or not you want to present the risk difference columns (default=TRUE) +# - Choose which risk difference method you would like (default=Wald) +# - Define what the control treatment group is for your study (e.g Placebo) +# - Define how to create combined treatment columns (if required) +# - Define lab parameters that are required for the optional section of the table +################################################################################ + +tblid <- "TSFAE07e" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +trtvar <- "TRT01A" +popfl <- "SAFFL" + +interest_var <- "CQ02NAM" # Change to the variable needed for analysis +interest_fl <- "AOCT02FL" # Change to the variable needed for analysis + +combined_colspan_trt <- TRUE +risk_diff <- TRUE +rr_method <- "wald" +ctrl_grp <- "Placebo" +combination_trt <- FALSE # Provide whether this is a combination treatments study + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +if (combination_trt) { + comb_trtvars <- c("AEDRGS1", "AEDRGS2") # Provide the variables containing combination treatment information in sequence + + n_comb_trt <- length(comb_trtvars) + + comb_relvars <- paste0("AERELS", seq_len(n_comb_trt)) # This will create a variable list like AERELS1, AERELS2 etc +} else if (!combination_trt) { + comb_trtvars <- trtvar + comb_relvars <- "AEREL" +} + +# Optional lab section parameters +labsection <- TRUE +lab_params <- c("AST", "ALT") +lab_labels <- c("AST>5xULN", "ALT>5xULN") +lab_var <- c("MCRIT1MN", "MCRIT1MN") +lab_vals <- c("2,3", "2,3") # Note both character or numeric values can be enclosed within in one set of double quotations here + +################################################################################ +# Process Data: +################################################################################ + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + + +lbdata <- NULL + +# Optional lab section +if (labsection == TRUE) { + for (i in 1:length(lab_params)) { + filter_val <- unlist(strsplit(lab_vals[[i]], ",")) + + adlb <- adlb_jnj |> + filter( + TRTEMFL == "Y" & + PARAMCD == lab_params[[i]] & + !!rlang::sym(lab_var[[i]]) %in% filter_val + ) |> + mutate(criteria = lab_labels[[i]]) |> + select(USUBJID, TRTEMFL, PARAMCD, all_of(lab_var[[i]]), criteria) + + lbdata <- bind_rows(adlb, lbdata) + } + + adlb <- lbdata |> + group_by(USUBJID, TRTEMFL, PARAMCD, criteria) |> + slice(1) |> + ungroup() + + # Create flag variable for each parameter that met the condition to merge back onto adsl + # Overall row + adlbparamall <- adlb |> + filter(PARAMCD %in% lab_params) |> + mutate(lab_flag = "Y") |> + group_by(USUBJID) |> + slice(1) |> + ungroup() |> + select(USUBJID, lab_flag) + + adsl <- left_join(adsl, adlbparamall, by = c("USUBJID")) + + # Loop through each parameter that the user has specified and merge flag variable onto adsl + for (i in 1:length(lab_params)) { + flagvar <- paste0("lab_flag", i) + + adlbparam <- adlb |> + filter(PARAMCD == lab_params[[i]] & criteria == lab_labels[[i]]) |> + mutate(!!flagvar := lab_labels[[i]]) |> + group_by(USUBJID) |> + slice(1) |> + ungroup() |> + select(USUBJID, all_of(flagvar)) + adsl <- left_join(adsl, adlbparam, by = c("USUBJID")) + } +} + +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & !is.na(!!rlang::sym(interest_var))) |> + select( + USUBJID, + TRTEMFL, + all_of(comb_trtvars), + AEDECOD, + AETOXGR, + AETOXGRN, + all_of(interest_var), + all_of(interest_fl), + AESER, + AEOUT, + all_of(comb_relvars), + AESDTH, + AESLIFE, + AESHOSP, + AESDISAB, + AESCONG, + AESMIE, + TRDISCFL + ) |> + select( + -any_of(trtvar) + ) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +if (risk_diff == TRUE) { + adsl$rrisk_header <- "Risk Difference (%) (95% CI)" + adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) +} + +# join data together +ae <- adae |> inner_join(adsl, by = c("USUBJID")) + +# Keep only maximum toxicity for the particular AESI +ae <- ae |> + group_by(USUBJID, .data[[interest_var]]) |> + mutate(ATOXGR = AETOXGRN[which(.data[[interest_fl]] == "Y")][1]) |> + ungroup() |> + mutate(ATOXGR = ifelse(is.na(ATOXGR), "Missing", paste("Grade", ATOXGR))) |> + mutate( + ATOXGR = factor( + ATOXGR, + levels = c( + "Grade 5", + "Grade 4", + "Grade 3", + "Grade 2", + "Grade 1", + "Missing" + ) + ), + rowhead = "Worst toxicity" + ) + +# Remove Missing as a level since not required in table +levels(ae$ATOXGR)[levels(ae$ATOXGR) == "Missing"] <- NA + +if (combination_trt) { + comb_rel_ae_labels <- paste(sapply(comb_trtvars, \(x) unique(adae[[x]])[1]), "related~[super b]") +} else if (!combination_trt) { + comb_rel_ae_labels <- "Related~[super b]" +} + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +################################################################################ +# Define layout and build table: +################################################################################ + +ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") +extra_args_rr <- list( + method = rr_method, + ref_path = ref_path, + .stats = c("count_unique_fraction") +) + +lyt <- basic_table( + top_level_section_div = " ", + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (risk_diff == TRUE) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels("Placebo") + ) +} + +lyt <- lyt |> + split_rows_by( + interest_var, + split_label = "", + split_fun = trim_levels_in_group("AEDECOD"), + label_pos = "topleft", + indent_mod = 0, + section_div = c(" ") + ) |> + summarize_row_groups( + interest_var, + cfun = a_freq_j, + extra_args = append(extra_args_rr, NULL) + ) |> + analyze( + "AEDECOD", + var_labels = "Preferred term", + afun = a_freq_j, + indent_mod = 0, + show_labels = "visible", + extra_args = append(extra_args_rr, NULL) + ) |> + split_rows_by( + "rowhead", + split_label = "", + label_pos = "topleft", + indent_mod = 0, + section_div = c(" ") + ) |> + analyze( + "ATOXGR", + afun = a_freq_j, + indent_mod = 0, + extra_args = append(extra_args_rr, NULL) + ) |> + split_rows_by( + "AESER", + split_fun = keep_split_levels("Y"), + section_div = " " + ) |> + summarize_row_groups( + "AESER", + cfun = a_freq_j, + extra_args = append(extra_args_rr, list(label = "SAE classification~[super a]", NULL)) + ) |> + analyze( + "AESDTH", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Death", val = "Y", NULL) + ) + ) |> + analyze( + "AESLIFE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Life-threatening", val = "Y", NULL) + ) + ) |> + analyze( + "AESHOSP", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Requires or prolongs hospitalization", val = "Y", NULL) + ) + ) |> + analyze( + "AESDISAB", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list( + label = "Persistent or significant disability/incapacity", + val = "Y", + NULL + ) + ) + ) |> + analyze( + "AESCONG", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append( + extra_args_rr, + list(label = "Congenital anomaly or birth defect", val = "Y", NULL) + ) + ) |> + analyze( + "AESMIE", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append(extra_args_rr, list(label = "Other medically important event", val = "Y", NULL)) + ) |> + analyze( + "TRDISCFL", + afun = a_freq_j, + show_labels = "hidden", + at_sibling = "AESER", + extra_args = append( + extra_args_rr, + list( + label = "Leading to permanent discontinuation of study treatment", + val = "Y", + NULL + ) + ) + ) + +for (i in seq_along(comb_relvars)) { + lyt <- lyt |> + analyze( + comb_relvars[i], + afun = a_freq_j, + show_labels = "hidden", + at_sibling = if (i == 1) "TRDISCFL" else NULL, + extra_args = append( + extra_args_rr, + list(label = comb_rel_ae_labels[i], val = toupper("Related"), NULL) + ) + ) +} + +if (labsection == TRUE) { + lyt <- lyt |> + analyze( + "lab_flag", + afun = a_freq_j, + show_labels = "hidden", + at_sibling = comb_relvars[1], + extra_args = append( + extra_args_rr, + list(label = "Laboratory assessment~[super c]", NULL) + ) + ) + + for (i in 1:length(lab_params)) { + aflagvar <- paste0("lab_flag", i) + + lyt <- lyt |> + analyze( + aflagvar, + afun = a_freq_j, + indent_mod = 1, + show_labels = "hidden", + nested = TRUE, + extra_args = append(extra_args_rr, NULL) + ) + } +} + +lyt <- lyt |> + append_topleft("AE of Interest Assessment, n (%)") + +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +## Remove any rogue null rows +result <- suppressWarnings(safe_prune_table( + result, + prune_func = count_pruner( + cat_exclude = c( + "Grade 1", + "Grade 2", + "Grade 3", + "Grade 4", + "Grade 5" + ) + ) +)) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21, 33, 29) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae08.R b/tests/testthat/source_code/tsfae08.R index 049c1b59..dcba7bac 100644 --- a/tests/testthat/source_code/tsfae08.R +++ b/tests/testthat/source_code/tsfae08.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae08.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae08: AE table by SOC/PT (excl. serious AEs) - TEAEs > x% -## Author: Johnson & Johnson Innovative Medicine -## Date: 12 Dec 2023 -## Input: ADSL, ADAE. -## Output: TSFAE08.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -37,6 +13,9 @@ library(junco) # - Define treatment variable used (default=TRT01A) # - Define population flag used (default=SAFFL) # - Choose whether or not you want to present a combined active treatment column (default=TRUE) +# - Choose whether or not you want to present the risk difference columns (default=TRUE) +# - Choose which risk difference method you would like (default=Wald) +# - Define what the control treatment group is for your study (e.g Placebo) # - Define how to create combined treatment columns (if required) ################################################################################ @@ -48,9 +27,16 @@ tab_titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) + trtvar <- "TRT01A" popfl <- "SAFFL" +subjFilterText <- "Subjects with >=1 AE leading to [dose modification]" combined_colspan_trt <- TRUE +risk_diff <- TRUE +rr_method <- "wald" +ctrl_grp <- "Placebo" +combination_trt <- FALSE # Provide whether this is a combination treatments study + if (combined_colspan_trt == TRUE) { # Set up levels and label for the required combined columns @@ -71,29 +57,75 @@ if (combined_colspan_trt == TRUE) { mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) } +if (combination_trt) { + comb_trtvars <- "AEDRGS1" # Provide the variable containing combination treatment information to use +} + +if (combination_trt) { + comb_acnvars <- paste0("AEACNS", sub(".*?(\\d+)$", "\\1", comb_trtvars)) # This will create a variable like AEACNS1/ AEACNS2 +} else if (!combination_trt) { + comb_acnvars <- "AEACN" +} + ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & AESER == "N") %>% - select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD) +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter( + TRTEMFL == "Y" & + !(.data[[comb_acnvars]] %in% + c( + "", + NA_character_, + "DRUG WITHDRAWN", + "DOSE NOT CHANGED", + "UNKNOWN", + "NOT APPLICABLE" + )) + ) |> + select(USUBJID, TRTEMFL, all_of(comb_acnvars), AEBODSYS, AEDECOD) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), levels = c("Active Study Agent", " ") ) +if (risk_diff == TRUE) { + adsl$rrisk_header <- "Risk Difference (%) (95% CI)" + adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) +} + # join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +ae <- adae |> right_join(adsl, by = c("USUBJID")) colspan_trt_map <- create_colspan_map( adsl, - non_active_grp = "Placebo", + non_active_grp = ctrl_grp, non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", @@ -104,66 +136,73 @@ colspan_trt_map <- create_colspan_map( # Define layout and build table: ################################################################################ -extra_args_1 <- list( - denom = "n_altdf", +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) +extra_args_rr <- list( + method = rr_method, + ref_path = ref_path, .stats = c("count_unique_fraction") ) -lyt <- rtables::basic_table( +lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +if (risk_diff == TRUE) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels("Placebo") + ) +} + +lyt <- lyt |> analyze( "TRTEMFL", afun = a_freq_j, show_labels = "hidden", extra_args = append( - extra_args_1, - list(label = "Subjects with >=1 AE", val = "Y") + extra_args_rr, + list(label = subjFilterText, NULL) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", - child_labels = "hidden", split_label = "System Organ Class", - label_pos = "topleft", split_fun = trim_levels_in_group("AEDECOD"), + label_pos = "topleft", section_div = c(" "), - indent_mod = 0L - ) %>% + nested = FALSE + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, - extra_args = extra_args_1 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) %>% + extra_args = append(extra_args_rr, NULL) + ) |> + analyze( + "AEDECOD", + afun = a_freq_j, + extra_args = append(extra_args_rr, NULL) + ) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) - -# If there is no data remove top row and display "No data to display" text -if (length(adae$TRTEMFL) == 0) { - result <- safe_prune_table( - result, - prune_func = remove_rows(removerowtext = "Subjects with >=1 AE") - ) -} +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -183,17 +222,16 @@ if (length(adae$TRTEMFL) != 0) { c("root", "AEBODSYS", "*", "AEDECOD"), scorefun = jj_complex_scorefun() ) +} + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) - ################################################################################ - # Prune table to only keep those that meet x% criteria, but top row is not subject to pruning - ################################################################################ +# If there is no data remove top row and display "No data to display" text +if (length(adae$TRTEMFL) == 0) { result <- safe_prune_table( result, - prune_func = bspt_pruner( - fraction = 0.05, - keeprowtext = "Subjects with >=1 AE", - cols = c(trtvar) - ) + prune_func = remove_rows(removerowtext = subjFilterText) ) } @@ -207,6 +245,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 21) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") +colwidth <- c(64, 21, 21, 21, 21, 33, 33) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae09.R b/tests/testthat/source_code/tsfae09.R index 500f7e13..68ca0b65 100644 --- a/tests/testthat/source_code/tsfae09.R +++ b/tests/testthat/source_code/tsfae09.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae09.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae09: AE table by SOC - TEAEs -## Author: Johnson & Johnson Innovative Medicine -## Date: 01 Dec 2023 -## Input: ADSL, ADAE. -## Output: TSFAE09.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -32,158 +8,153 @@ library(junco) # Define script level parameters: ################################################################################ -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - tblid <- "TSFAE09" fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) -trtvar <- "TRT01A" -popfl <- "SAFFL" -combined_colspan_trt <- TRUE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" +eair_stats <- "n_eair" # current shell +# eair_stats <- "eair_n_py" # alternative shell -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +# for sorting function +# sorting should be performed on values of eair, +# which are second values in cellvalue +# set the appropriate cellvalue_index for usage in jj_complex_scorefun +cv_index <- 1 +if (eair_stats == "n_eair") { + cv_index <- 2 } + ################################################################################ -# Process Data: +# Process data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% - select(USUBJID, TRTEMFL, AEBODSYS) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) +adexsum <- adexsum_jnj |> + filter(!!rlang::sym(popfl) == "Y" & PARAMCD == "TRTDURY") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + mutate( + rrisk_header = "Incidence Rate Difference (95% CI)", + rrisk_label = paste(!!rlang::sym(trtvar), "vs", ctrl_grp), + TRTDURY = AVAL + ) |> + select( + USUBJID, + !!rlang::sym(trtvar), + colspan_trt, + rrisk_header, + rrisk_label, + TRTDURY + ) -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) -} +adae <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y" & AOCCPFL == "Y") |> + select(USUBJID, AEDECOD, ASTDY, AOCCPFL) -# join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) +# join -- -- subjects without ae will be handled via alt_counts_df dataframe +aefup <- right_join(adae, adexsum, by = "USUBJID") colspan_trt_map <- create_colspan_map( - adsl, + adexsum, non_active_grp = ctrl_grp, non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar ) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) ################################################################################ # Define layout and build table: ################################################################################ -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - - lyt <- basic_table( - top_level_section_div = " ", show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% + colcount_format = "N=xx", + top_level_section_div = " " +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) + ) |> + split_cols_by(trtvar) |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels(ctrl_grp) + ) |> + analyze( + "TRTDURY", + nested = FALSE, + show_labels = "hidden", + afun = a_patyrs_j, + extra_args = list(.labels = c(patyrs = "Subject years~[super a]")) + ) |> + analyze( + vars = "AEDECOD", + nested = FALSE, + afun = a_eair100_j, + extra_args = list( + fup_var = "TRTDURY", + occ_var = "AOCCPFL", + occ_dy = "ASTDY", + ref_path = ref_path, + .stats = eair_stats, + drop_levels = TRUE, + row_labels_adj = TRUE + ) + ) |> + append_topleft("Preferred Term, n (EAIR Per 100 SY)") -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) -} +result <- build_table(lyt, aefup, alt_counts_df = adexsum) -lyt <- lyt %>% - analyze( - "AEBODSYS", - afun = a_freq_j, - extra_args = append(extra_args_rr, list(drop_levels = TRUE)), - indent_mod = 0L - ) %>% - append_topleft("System Organ Class, n (%)") - -result <- build_table(lyt, ae, alt_counts_df = adsl) - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (length(adae$TRTEMFL) != 0) { - result <- sort_at_path( - result, - c("AEBODSYS"), - scorefun = jj_complex_scorefun() + +################################################################################ +# Post-Processing: +# - Remove Ns from Risk cols +# - Sort by descending AEDECOD in the combined Xanomeline High Dose column +################################################################################ +result <- result |> + sort_at_path( + path = c("AEDECOD"), + scorefun = jj_complex_scorefun( + colpath = "Xanomeline High Dose", + cellvalue_index = cv_index + ) ) -} -## Remove the N=xx column headers for the risk difference columns result <- remove_col_count(result) -## Remove any rogue null rows -result <- result %>% - safe_prune_table(prune_func = keep_rows(keep_non_null_rows)) - ################################################################################ # Add titles and footnotes: ################################################################################ @@ -191,9 +162,10 @@ result <- result %>% result <- set_titles(result, tab_titles) ################################################################################ -# Convert to tbl file and output table +# Convert to tbl file and output table: ################################################################################ -colwidth <- c(64, 21, 21, 21, 21, 31, 31) + +colwidth <- c(52, 18, 18, 16, 39, 37) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae10.R b/tests/testthat/source_code/tsfae10.R deleted file mode 100644 index 20693ac0..00000000 --- a/tests/testthat/source_code/tsfae10.R +++ /dev/null @@ -1,216 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae10.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae10: AE table of Related TEAEs ≥[X]% by Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 01 Dec 2023 -## Input: ADSL, ADAE. -## Output: TSFAE10.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Define the ADaM Variable to choose the AE related variable(s) -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE10" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - - -trtvar <- "TRT01A" -popfl <- "SAFFL" - -aerelvar <- "AEREL" - -combined_colspan_trt <- TRUE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -# define criteria for related AE -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & !!rlang::sym(aerelvar) == "RELATED") %>% - select(USUBJID, TRTEMFL, AEDECOD) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) -} - -# join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) - - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) -} - -lyt <- lyt %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = append(extra_args_rr, NULL), - show_labels = "hidden" - ) %>% - append_topleft("Preferred Term, n (%)") - -result <- build_table(lyt, ae, alt_counts_df = adsl) - -if (length(adae$TRTEMFL) != 0) { - ######################################################################################### - # Post-Processing step to sort by descending count on chosen active treatment columns. - # Default is the last treatment (inc. Combined if applicable) under the active treatment - # spanning header (defaulted to colspan_trt variable). See function documentation for - # jj_complex_scorefun should your require a different sorting behavior. - ######################################################################################### - - result <- sort_at_path(result, c("AEDECOD"), scorefun = jj_complex_scorefun()) - - ################################################################################ - # Prune table to only keep those that meet x% criteria on any treatment column - ################################################################################ - more_than_x_percent <- has_fraction_in_any_col( - atleast = 0.05, - col_names = c( - "Active Study Agent.Xanomeline High Dose", - "Active Study Agent.Xanomeline Low Dose", - " .Placebo" - ) - ) - - result <- safe_prune_table(result, keep_rows(more_than_x_percent)) -} - -## Remove any rogue null rows -result <- result %>% - safe_prune_table(prune_func = keep_rows(keep_non_null_rows)) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 17, 17, 17, 17, 31, 31) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae10a.R b/tests/testthat/source_code/tsfae10a.R new file mode 100644 index 00000000..90df219a --- /dev/null +++ b/tests/testthat/source_code/tsfae10a.R @@ -0,0 +1,261 @@ +library(envsetup) +library(tern) +library(forcats) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFAE10a" +titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +trtvar <- "TRT01A" +subjFilterText <- "AE" +ctrl_grp <- "Placebo" + +################################################################################ +# Process Data +# - Sub-setting performed on a subject-level; certain tables may require a more +# granular, column-based sub-setting. +# - Factor for Active Treatment spanning header added below. +# - Additional factor reformatting added below. +################################################################################ + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + # Canonical demographics decoding (replace * usage) + SEX = factor( + dplyr::case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male", + SEX == "U" ~ "Unknown", + SEX == "INTERSEX" ~ "Intersex" + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + AGEGR1 = factor( + AGEGR1, + levels = c(">=18 to <65", ">=65 to <75", ">=75") + ), + RACE = factor( + dplyr::case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + ETHNIC = factor( + dplyr::case_when( + ETHNIC == "HISPANIC OR LATINO" ~ "Hispanic or Latino", + ETHNIC == "NOT HISPANIC OR LATINO" ~ "Not Hispanic or Latino", + ETHNIC == "NOT REPORTED" ~ "Not reported", + ETHNIC == "UNKNOWN" ~ "Unknown" + ), + levels = c("Hispanic or Latino", "Not Hispanic or Latino", "Not reported", "Unknown") + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + select( + USUBJID, + !!rlang::sym(popfl), + !!rlang::sym(trtvar), + SEX, + AGEGR1, + RACE, + ETHNIC, + colspan_trt + ) + + +# Factor reformatting (e.g., Include missing in the "Unknown" category). +adsl$SEX <- forcats::fct_na_value_to_level( + adsl$SEX, + level = "Unknown" +) + +adsl$AGEGR1 <- forcats::fct_na_value_to_level( + adsl$AGEGR1, + level = "Unknown" +) + +adsl$RACE <- forcats::fct_collapse( + forcats::fct_na_value_to_level(adsl$RACE, level = "Unknown"), + "Not reported or unknown" = c("Not reported", "Unknown") +) + +adsl$ETHNIC <- forcats::fct_collapse( + forcats::fct_na_value_to_level(adsl$ETHNIC, level = "Unknown"), + "Not reported or unknown" = c("Not reported", "Unknown") +) + +had_ae <- adae_jnj |> + filter(TRTEMFL == "Y") |> + select(USUBJID, TRTEMFL) |> + distinct(USUBJID, .keep_all = TRUE) + +adsl <- adsl |> + left_join(had_ae) |> + mutate(TRTEMFL = ifelse(is.na(TRTEMFL), "N", "Y")) + +################################################################################ +# Define layout and build table +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +add_active_combo <- make_split_fun( + post = list( + add_combo_facet( + name = "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ), + cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + ) +) + +extra_args_rr <- list( + riskdiff = FALSE +) + +extra_args_rr2 <- append( + extra_args_rr, + list(resp_var = "TRTEMFL", drop_levels = TRUE) +) + +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx", + top_level_section_div = " " +) |> + append_topleft("Characteristic") |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) |> + split_cols_by(trtvar, split_fun = add_active_combo) + +lyt <- lyt |> + analyze( + "TRTEMFL", + afun = a_freq_j, + extra_args = append( + extra_args_rr, + list( + label = paste("Subjects with >= 1", subjFilterText), + val = "Y", + .stats = c("count_unique_fraction") + ) + ), + show_labels = "hidden" + ) |> + analyze( + vars = "SEX", + var_labels = "Sex, n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) |> + analyze( + vars = "AGEGR1", + var_labels = "Age group (years), n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) |> + analyze( + vars = "RACE", + var_labels = "Race, n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) |> + analyze( + vars = "ETHNIC", + var_labels = "Ethnicity, n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) + +result <- build_table(lyt, adsl, round_type = "sas") + +################################################################################ +# Post-Processing: +# Prune any categories with all zeros: +################################################################################ + +result <- safe_prune_table(result, prune_func = count_pruner()) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 27, 27, 29, 27) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae10b.R b/tests/testthat/source_code/tsfae10b.R new file mode 100644 index 00000000..5bc9ada9 --- /dev/null +++ b/tests/testthat/source_code/tsfae10b.R @@ -0,0 +1,257 @@ +library(envsetup) +library(tern) +library(forcats) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFAE10b" +titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +trtvar <- "TRT01A" +subjFilterText <- "SAE" +ctrl_grp <- "Placebo" + +################################################################################ +# Process Data +# - Sub-setting performed on a subject-level; certain tables may require a more +# granular, column-based sub-setting. +# - Factor for Active Treatment spanning header added below. +# - Additional factor reformatting added below. +################################################################################ + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + AGEGR1 = factor( + AGEGR1, + levels = c(">=18 to <65", ">=65 to <75", ">=75") + ), + SEX = factor( + dplyr::case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male", + SEX == "U" ~ "Unknown", + SEX == "INTERSEX" ~ "Intersex" + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + dplyr::case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + ETHNIC = factor( + dplyr::case_when( + ETHNIC == "HISPANIC OR LATINO" ~ "Hispanic or Latino", + ETHNIC == "NOT HISPANIC OR LATINO" ~ "Not Hispanic or Latino", + ETHNIC == "NOT REPORTED" ~ "Not reported", + ETHNIC == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Hispanic or Latino", + "Not Hispanic or Latino", + "Not reported", + "Unknown" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + select( + USUBJID, + !!rlang::sym(popfl), + !!rlang::sym(trtvar), + SEX, + AGEGR1, + RACE, + ETHNIC, + colspan_trt + ) + +# Factor reformatting (e.g., Include missing in the "Unknown" category). +adsl$SEX <- forcats::fct_na_value_to_level( + adsl$SEX, + level = "Unknown" +) + +adsl$AGEGR1 <- forcats::fct_na_value_to_level( + adsl$AGEGR1, + level = "Unknown" +) + +adsl$RACE <- forcats::fct_collapse( + forcats::fct_na_value_to_level(adsl$RACE, level = "Unknown"), + "Not reported or unknown" = c("Not reported", "Unknown") +) + +adsl$ETHNIC <- forcats::fct_collapse( + forcats::fct_na_value_to_level(adsl$ETHNIC, level = "Unknown"), + "Not reported or unknown" = c("Not reported", "Unknown") +) + +had_ae <- adae_jnj |> + filter(TRTEMFL == "Y" & AESER == "Y") |> + select(USUBJID, TRTEMFL, AESER) |> + distinct(USUBJID, .keep_all = TRUE) + +adsl <- adsl |> + left_join(had_ae) |> + mutate(TRTEMFL = ifelse(is.na(TRTEMFL), "N", "Y")) + + +################################################################################ +# Define layout and build table +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +add_active_combo <- make_split_fun( + post = list( + add_combo_facet( + name = "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ), + cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + ) +) + +extra_args_rr <- list( + riskdiff = FALSE +) + +extra_args_rr2 <- append( + extra_args_rr, + list(resp_var = "TRTEMFL", drop_levels = TRUE) +) + +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx", + top_level_section_div = " " +) |> + append_topleft("Characteristic") |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) |> + split_cols_by(trtvar, split_fun = add_active_combo) + +lyt <- lyt |> + analyze( + "TRTEMFL", + afun = a_freq_j, + extra_args = append( + extra_args_rr, + list( + label = paste("Subjects with >= 1", subjFilterText), + val = "Y", + .stats = c("count_unique_fraction") + ) + ), + show_labels = "hidden" + ) |> + analyze( + vars = "SEX", + var_labels = "Sex, n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) |> + analyze( + vars = "AGEGR1", + var_labels = "Age group (years), n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) |> + analyze( + vars = "RACE", + var_labels = "Race, n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) |> + analyze( + vars = "ETHNIC", + var_labels = "Ethnicity, n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) + +result <- build_table(lyt, adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 27, 27, 27, 27) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae10c.R b/tests/testthat/source_code/tsfae10c.R new file mode 100644 index 00000000..1e72c07f --- /dev/null +++ b/tests/testthat/source_code/tsfae10c.R @@ -0,0 +1,236 @@ +library(envsetup) +library(tern) +library(forcats) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFAE10c" +titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +trtvar <- "TRT01A" +subjFilterText <- "dizziness" +varname <- "AEDECOD" +ctrl_grp <- "Placebo" + +################################################################################ +# Process Data +# - Sub-setting performed on a subject-level; certain tables may require a more +# granular, column-based sub-setting. +# - Factor for Active Treatment spanning header added below. +# - Additional factor reformatting added below. +################################################################################ + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ), + SEX = factor( + dplyr::case_when( + SEX == "F" ~ "Female", + SEX == "M" ~ "Male", + SEX == "U" ~ "Unknown", + SEX == "INTERSEX" ~ "Intersex" + ), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + RACE = factor( + dplyr::case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + ETHNIC = factor( + dplyr::case_when( + ETHNIC == "HISPANIC OR LATINO" ~ "Hispanic or Latino", + ETHNIC == "NOT HISPANIC OR LATINO" ~ "Not Hispanic or Latino", + ETHNIC == "NOT REPORTED" ~ "Not reported", + ETHNIC == "UNKNOWN" ~ "Unknown" + ), + levels = c("Hispanic or Latino", "Not Hispanic or Latino", "Not reported", "Unknown") + ), + AGEGR1 = factor( + AGEGR1, + levels = c(">=18 to <65", ">=65 to <75", ">=75") + ), + # Age Group: include Unknown + AGEGR1 = forcats::fct_na_value_to_level( + AGEGR1, + level = "Unknown" + ) + ) |> + create_colspan_var( + non_active_grp = "Placebo", + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + select( + USUBJID, + !!rlang::sym(popfl), + !!rlang::sym(trtvar), + SEX, + AGEGR1, + RACE, + ETHNIC, + colspan_trt + ) + +had_ae <- adaeocmq_jnj |> + filter(TRTEMFL == "Y" & tolower(.data[[varname]]) == tolower(subjFilterText)) |> + select(USUBJID, TRTEMFL) |> + distinct(USUBJID, .keep_all = TRUE) + +adsl <- adsl |> + left_join(had_ae) |> + mutate(TRTEMFL = ifelse(is.na(TRTEMFL), "N", "Y")) + +################################################################################ +# Define layout and build table +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +add_active_combo <- make_split_fun( + post = list( + add_combo_facet( + name = "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ), + cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + ) +) + +extra_args_rr <- list( + riskdiff = FALSE +) + +extra_args_rr2 <- append( + extra_args_rr, + list(resp_var = "TRTEMFL", drop_levels = TRUE) +) + +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx", + top_level_section_div = " " +) |> + append_topleft("Characteristic") |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) |> + split_cols_by(trtvar, split_fun = add_active_combo) + +lyt <- lyt |> + analyze( + "TRTEMFL", + afun = a_freq_j, + extra_args = append( + extra_args_rr, + list( + label = paste("Subjects with >= 1", subjFilterText), + val = "Y", + .stats = c("count_unique_fraction") + ) + ), + show_labels = "hidden" + ) |> + analyze( + vars = "SEX", + var_labels = "Sex, n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) |> + analyze( + vars = "AGEGR1", + var_labels = "Age group (years), n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) |> + analyze( + vars = "RACE", + var_labels = "Race, n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) |> + analyze( + vars = "ETHNIC", + var_labels = "Ethnicity, n/Ns (%)", + show_labels = "visible", + afun = a_freq_resp_var_j, + extra_args = extra_args_rr2, + nested = FALSE + ) + +result <- build_table(lyt, adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 25, 25, 27, 23) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae21a.R b/tests/testthat/source_code/tsfae11a.R similarity index 76% rename from tests/testthat/source_code/tsfae21a.R rename to tests/testthat/source_code/tsfae11a.R index 9d427806..3e7abc7b 100644 --- a/tests/testthat/source_code/tsfae21a.R +++ b/tests/testthat/source_code/tsfae11a.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae21a.R -## R version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae21a: TEAEs by severity (SOC / PT) - Variant 1 -## Author: Johnson & Johnson Innovative Medicine -## Date: 18 Dec 2023 -## Input: ADSL, ADAE. -## Output: TSFAE21a.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -40,7 +16,7 @@ library(junco) # - Define how to create combined treatment columns (if required) ################################################################################ -tblid <- "TSFAE21a" +tblid <- "TSFAE11a" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -75,31 +51,51 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> filter(TRTEMFL == "Y") # Take maximum severity - per PT -adaemaxpt <- adae %>% - filter(AESEV %in% c("Mild", "Moderate", "Severe")) %>% +adaemaxpt <- adae |> + filter(AESEV %in% c("Mild", "Moderate", "Severe")) |> mutate( AESEVN = case_when( toupper(AESEV) == "MILD" ~ 3, toupper(AESEV) == "MODERATE" ~ 2, toupper(AESEV) == "SEVERE" ~ 1 ) - ) %>% - arrange(USUBJID, AEBODSYS, AEDECOD, AESEVN) %>% - group_by(USUBJID, AEBODSYS, AEDECOD) %>% - slice(1) %>% + ) |> + arrange(USUBJID, AEBODSYS, AEDECOD, AESEVN) |> + group_by(USUBJID, AEBODSYS, AEDECOD) |> + slice(1) |> ungroup() # Take maximum severity - per SOC -adaemaxsoc <- adae %>% - filter(AESEV %in% c("Mild", "Moderate", "Severe")) %>% +adaemaxsoc <- adae |> + filter(AESEV %in% c("Mild", "Moderate", "Severe")) |> mutate( AESEVN = case_when( toupper(AESEV) == "MILD" ~ 3, @@ -107,11 +103,11 @@ adaemaxsoc <- adae %>% toupper(AESEV) == "SEVERE" ~ 1 ), AEBODSYSx = AEBODSYS - ) %>% - arrange(USUBJID, AEBODSYS, AESEVN) %>% - group_by(USUBJID, AEBODSYS) %>% - slice(1) %>% - ungroup() %>% + ) |> + arrange(USUBJID, AEBODSYS, AESEVN) |> + group_by(USUBJID, AEBODSYS) |> + slice(1) |> + ungroup() |> select(USUBJID, AEBODSYS, AESEV, AEBODSYSx) # Merge back in an create a new SOC variable that is only populated for max severity SOC rows @@ -122,24 +118,24 @@ adaemax <- left_join( ) # Add total -adaetot <- adae %>% +adaetot <- adae |> mutate( AESEV = "Total", AEBODSYSx = AEBODSYS - ) %>% - arrange(USUBJID, AEBODSYS, AEDECOD) %>% - group_by(USUBJID, AEBODSYS, AEDECOD) %>% - slice(1) %>% + ) |> + arrange(USUBJID, AEBODSYS, AEDECOD) |> + group_by(USUBJID, AEBODSYS, AEDECOD) |> + slice(1) |> ungroup() # Set data together -adaeall <- bind_rows(adaemax, adaetot) %>% +adaeall <- bind_rows(adaemax, adaetot) |> mutate( ASEV = factor( as.character(AESEV), levels = c("Total", "Mild", "Moderate", "Severe") ) - ) %>% + ) |> select(USUBJID, TRTEMFL, ASEV, AEBODSYS, AEBODSYSx, AEDECOD) adsl$colspan_trt <- factor( @@ -157,10 +153,10 @@ colspan_trt_map <- create_colspan_map( ) # join data together -ae <- adaeall %>% inner_join(., adsl, by = c("USUBJID")) +ae <- adaeall |> inner_join(adsl, by = c("USUBJID")) if (length(adae$TRTEMFL) == 0) { - ae <- adaeall %>% right_join(., adsl, by = c("USUBJID")) + ae <- adaeall |> right_join(adsl, by = c("USUBJID")) } ae$spanheader <- factor( @@ -168,10 +164,10 @@ ae$spanheader <- factor( levels = c(" ", "Severity") ) -adsl1 <- adsl %>% +adsl1 <- adsl |> mutate(AESEV = "Total") -adsl <- adsl1 %>% +adsl <- adsl1 |> mutate( ASEV = factor( as.character(AESEV), @@ -197,23 +193,23 @@ extra_args_1 <- list( lyt <- basic_table( top_level_section_div = " ", colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit, show_colcounts = TRUE) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, show_colcounts = TRUE) } -lyt <- lyt %>% - split_cols_by("spanheader", split_fun = trim_levels_in_group("ASEV")) %>% - split_cols_by("ASEV", show_colcounts = FALSE) %>% +lyt <- lyt |> + split_cols_by("spanheader", split_fun = trim_levels_in_group("ASEV")) |> + split_cols_by("ASEV", show_colcounts = FALSE) |> analyze( "TRTEMFL", afun = a_freq_j, @@ -226,23 +222,23 @@ lyt <- lyt %>% restr_columns = "Total" ) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", split_fun = trim_levels_in_group("AEDECOD"), label_pos = "topleft", section_div = c(" ") - ) %>% + ) |> summarize_row_groups( "AEBODSYSx", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) %>% + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -301,12 +297,12 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 21, 21, 21, 17, 23, 21, 21, 17, 21, 21, 19, 17) + +colwidth <- c(64, 21, 21, 21, 17, 21, 21, 21, 17, 21, 21, 21, 17, 21, 19, 17, 17) tt_to_tlgrtf( - colwidths = colwidth, result, file = fileid, - orientation = "portrait", + orientation = "landscape", nosplitin = list(cols = c(trtvar)) ) diff --git a/tests/testthat/source_code/tsfae21b.R b/tests/testthat/source_code/tsfae11b.R similarity index 78% rename from tests/testthat/source_code/tsfae21b.R rename to tests/testthat/source_code/tsfae11b.R index 179bd87f..8ea78ea0 100644 --- a/tests/testthat/source_code/tsfae21b.R +++ b/tests/testthat/source_code/tsfae11b.R @@ -1,27 +1,3 @@ -############################################################################################### -## Original Reporting Effort: Standards -## Program Name: tsfae21b.R -## R Version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae21b: TEAEs by toxicity (SOC / PT) - Variant 1 -## Author: Johnson & Johnson Innovative Medicine -## Date: 26 Feb 2024 -## Input: ADSL, ADAE. -## Output: TSFAE21b.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting effort: -## Date: -## Description: -############################################################################################### - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -42,7 +18,7 @@ library(junco) # - Option to exclude Grade 5 columns if there are none (default = TRUE but set to FALSE if you want this column regardless) ################################################################################ -tblid <- "TSFAE21b" +tblid <- "TSFAE11b" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -80,29 +56,49 @@ exclude_G5_if_none <- TRUE # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> filter(TRTEMFL == "Y") # Take maximum toxicity - per PT -adaemaxpt <- adae %>% - filter(AETOXGR %in% c("1", "2", "3", "4", "5")) %>% - arrange(USUBJID, AEBODSYS, AEDECOD, AETOXGRN) %>% - group_by(USUBJID, AEBODSYS, AEDECOD) %>% - slice_tail() %>% +adaemaxpt <- adae |> + filter(AETOXGR %in% c("1", "2", "3", "4", "5")) |> + arrange(USUBJID, AEBODSYS, AEDECOD, AETOXGRN) |> + group_by(USUBJID, AEBODSYS, AEDECOD) |> + slice_tail() |> ungroup() # Take maximum toxicity - per SOC -adaemaxsoc <- adae %>% - filter(AETOXGR %in% c("1", "2", "3", "4", "5")) %>% - mutate(AEBODSYSx = AEBODSYS) %>% - arrange(USUBJID, AEBODSYS, AETOXGRN) %>% - group_by(USUBJID, AEBODSYS) %>% - slice_tail() %>% - ungroup() %>% +adaemaxsoc <- adae |> + filter(AETOXGR %in% c("1", "2", "3", "4", "5")) |> + mutate(AEBODSYSx = AEBODSYS) |> + arrange(USUBJID, AEBODSYS, AETOXGRN) |> + group_by(USUBJID, AEBODSYS) |> + slice_tail() |> + ungroup() |> select(USUBJID, AEBODSYS, AETOXGR, AEBODSYSx) # Merge back in an create a new SOC variable that is only populated for max toxicity SOC rows @@ -113,24 +109,24 @@ adaemax <- left_join( ) # Add total -adaetot <- adae %>% +adaetot <- adae |> mutate( AETOXGR = "Total", AEBODSYSx = AEBODSYS - ) %>% - arrange(USUBJID, AEBODSYS, AEDECOD) %>% - group_by(USUBJID, AEBODSYS, AEDECOD) %>% - slice(1) %>% + ) |> + arrange(USUBJID, AEBODSYS, AEDECOD) |> + group_by(USUBJID, AEBODSYS, AEDECOD) |> + slice(1) |> ungroup() # Set data together -adaeall <- bind_rows(adaemax, adaetot) %>% +adaeall <- bind_rows(adaemax, adaetot) |> mutate( AETOXGR = factor( as.character(AETOXGR), levels = c("Total", "1", "2", "3", "4", "5") ) - ) %>% + ) |> select(USUBJID, TRTEMFL, AETOXGR, AEBODSYS, AEBODSYSx, AEDECOD) adsl$colspan_trt <- factor( @@ -148,10 +144,10 @@ colspan_trt_map <- create_colspan_map( ) # join data together -ae <- adaeall %>% inner_join(., adsl, by = c("USUBJID")) +ae <- adaeall |> inner_join(adsl, by = c("USUBJID")) if (length(adae$TRTEMFL) == 0) { - ae <- adaeall %>% right_join(., adsl, by = c("USUBJID")) + ae <- adaeall |> right_join(adsl, by = c("USUBJID")) } ae$spanheader <- factor( @@ -159,10 +155,10 @@ ae$spanheader <- factor( levels = c(" ", "Toxicity Grade") ) -adsl1 <- adsl %>% +adsl1 <- adsl |> mutate(AETOXGR = "Total") -adsl <- adsl1 %>% +adsl <- adsl1 |> mutate( AETOXGR = factor( as.character(AETOXGR), @@ -189,7 +185,7 @@ grademap <- data.frame( ) # If there are no grade 5 and user has asked to exclude column then update factors -anyG5 <- ae %>% +anyG5 <- ae |> filter(AETOXGR == "5") if (exclude_G5_if_none == TRUE && length(anyG5$AETOXGR) == 0) { @@ -220,26 +216,26 @@ extra_args_1 <- list( lyt <- basic_table( top_level_section_div = " ", colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit, show_colcounts = TRUE) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, show_colcounts = TRUE) } -lyt <- lyt %>% +lyt <- lyt |> split_cols_by( "spanheader", split_fun = trim_levels_to_map(map = grademap) - ) %>% - split_cols_by("AETOXGR", show_colcounts = FALSE) %>% + ) |> + split_cols_by("AETOXGR", show_colcounts = FALSE) |> analyze( "TRTEMFL", afun = a_freq_j, @@ -252,23 +248,23 @@ lyt <- lyt %>% restr_columns = "Total" ) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", split_fun = trim_levels_in_group("AEDECOD"), label_pos = "topleft", section_div = c(" ") - ) %>% + ) |> summarize_row_groups( "AEBODSYSx", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) %>% + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -327,10 +323,10 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 17, 19, 17, 21, 21, 21, 17, 17, 17, 21, 19, 23, 17, 19, 17, 21, 21, 21, 17, 17, 17, 17, 17) + +colwidth <- c(64, 21, 17, 17, 17, 19, 21, 21, 17, 19, 17, 19, 19, 21, 17, 19, 17, 19, 21, 21, 17, 17, 17, 17, 19) tt_to_tlgrtf( - colwidths = colwidth, result, file = fileid, orientation = "landscape", diff --git a/tests/testthat/source_code/tsfae21c.R b/tests/testthat/source_code/tsfae11c.R similarity index 80% rename from tests/testthat/source_code/tsfae21c.R rename to tests/testthat/source_code/tsfae11c.R index 088ac80e..1fa99033 100644 --- a/tests/testthat/source_code/tsfae21c.R +++ b/tests/testthat/source_code/tsfae11c.R @@ -1,27 +1,3 @@ -############################################################################################### -## Original Reporting Effort: Standards -## Program Name: tsfae21c.R -## R Version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae21c: TEAEs by severity (SOC / PT) - Variant 1 Alternative format -## Author: Johnson & Johnson Innovative Medicine -## Date: 26 Feb 2024 -## Input: ADSL, ADAE. -## Output: TSFAE21c.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting effort: -## Date: -## Description: -############################################################################################### - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -41,7 +17,7 @@ library(junco) # - Define column widths to help with desired page splitting ################################################################################ -tblid <- "TSFAE21c" +tblid <- "TSFAE11c" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -76,16 +52,36 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> select(USUBJID, AEBODSYS, AEDECOD, TRTEMFL, AESEV) # Take maximum severity -adaemax <- adae %>% +adaemax <- adae |> mutate( AESEVN = case_when( toupper(AESEV) == "MILD" ~ 3, @@ -93,10 +89,10 @@ adaemax <- adae %>% toupper(AESEV) == "SEVERE" ~ 1, .default = 99 ) - ) %>% - arrange(USUBJID, AEBODSYS, AEDECOD, AESEVN) %>% - group_by(USUBJID, AEBODSYS, AEDECOD) %>% - slice(1) %>% + ) |> + arrange(USUBJID, AEBODSYS, AEDECOD, AESEVN) |> + group_by(USUBJID, AEBODSYS, AEDECOD) |> + slice(1) |> ungroup() adsl$colspan_trt <- factor( @@ -116,13 +112,13 @@ colspan_trt_map <- create_colspan_map( # join data together ae <- inner_join(adaemax, adsl, by = c("USUBJID")) -ae <- ae %>% +ae <- ae |> mutate(AESEV2 = as.factor(ifelse(is.na(AESEV), "Missing", AESEV))) if (length(adae$TRTEMFL) == 0) { ae <- right_join(adaemax, adsl, by = c("USUBJID")) - ae <- ae %>% + ae <- ae |> mutate(AESEV2 = as.factor(ifelse(is.na(AESEV), "Missing", AESEV))) } @@ -141,21 +137,21 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> analyze( "TRTEMFL", afun = a_freq_j, @@ -164,7 +160,7 @@ lyt <- lyt %>% extra_args_1, list(label = "Subjects with >=1 AE", val = "Y") ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", @@ -172,27 +168,27 @@ lyt <- lyt %>% label_pos = "topleft", section_div = c(" "), nested = FALSE - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% + ) |> split_rows_by( "AEDECOD", split_label = "Preferred Term, n (%)", section_div = c(" "), nested = TRUE - ) %>% + ) |> summarize_row_groups( "AEDECOD", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% - analyze("AESEV2", afun = a_freq_j, extra_args = extra_args_1) %>% + ) |> + analyze("AESEV2", afun = a_freq_j, extra_args = extra_args_1) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -230,10 +226,10 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 23, 21) + +colwidth <- c(64, 21, 21, 21, 21) tt_to_tlgrtf( - colwidths = colwidth, result, file = fileid, orientation = "portrait", diff --git a/tests/testthat/source_code/tsfae21d.R b/tests/testthat/source_code/tsfae11d.R similarity index 80% rename from tests/testthat/source_code/tsfae21d.R rename to tests/testthat/source_code/tsfae11d.R index 92910805..a24ee7f5 100644 --- a/tests/testthat/source_code/tsfae21d.R +++ b/tests/testthat/source_code/tsfae11d.R @@ -1,27 +1,3 @@ -############################################################################################### -## Original Reporting Effort: Standards -## Program Name: tsfae21d.R -## R Version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae21d: TEAEs by toxicity (SOC / PT) - Variant 2 Alternative format -## Author: Johnson & Johnson Innovative Medicine -## Date: 26 Feb 2024 -## Input: ADSL, ADAE. -## Output: TSFAE21d.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting effort: -## Date: -## Description: -############################################################################################### - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -41,7 +17,7 @@ library(junco) # - Define column widths to help with desired page splitting ################################################################################ -tblid <- "TSFAE21d" +tblid <- "TSFAE11d" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -77,16 +53,36 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> select(USUBJID, AEBODSYS, AEDECOD, TRTEMFL, AETOXGR) # Take maximum toxicity -adaemax <- adae %>% +adaemax <- adae |> mutate( AETOXGRN = case_when( AETOXGR == "1" ~ 5, @@ -96,10 +92,10 @@ adaemax <- adae %>% AETOXGR == "5" ~ 1, .default = 99 ) - ) %>% - arrange(USUBJID, AEBODSYS, AEDECOD, AETOXGRN) %>% - group_by(USUBJID, AEBODSYS, AEDECOD) %>% - slice(1) %>% + ) |> + arrange(USUBJID, AEBODSYS, AEDECOD, AETOXGRN) |> + group_by(USUBJID, AEBODSYS, AEDECOD) |> + slice(1) |> ungroup() adsl$colspan_trt <- factor( @@ -117,7 +113,7 @@ colspan_trt_map <- create_colspan_map( ) # join data together, and Grade for table display -ae <- inner_join(adaemax, adsl, by = c("USUBJID")) %>% +ae <- inner_join(adaemax, adsl, by = c("USUBJID")) |> mutate( AETOXGRx = factor( as.character(paste0("Grade ", AETOXGR)), @@ -125,18 +121,18 @@ ae <- inner_join(adaemax, adsl, by = c("USUBJID")) %>% ) ) -ae <- ae %>% +ae <- ae |> mutate(AETOXGR2 = as.factor(ifelse(is.na(AETOXGRx), "Missing", AETOXGRx))) if (length(adae$TRTEMFL) == 0) { - ae <- right_join(adaemax, adsl, by = c("USUBJID")) %>% + ae <- right_join(adaemax, adsl, by = c("USUBJID")) |> mutate( AETOXGRx = factor( as.character(paste0("Grade ", AETOXGR)), levels = c("Grade 1", "Grade 2", "Grade 3", "Grade 4", "Grade 5") ) ) - ae <- ae %>% + ae <- ae |> mutate(AETOXGR2 = as.factor(ifelse(is.na(AETOXGRx), "Missing", AETOXGRx))) } @@ -155,21 +151,21 @@ lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> analyze( "TRTEMFL", afun = a_freq_j, @@ -178,7 +174,7 @@ lyt <- lyt %>% extra_args_1, list(label = "Subjects with >=1 AE", val = "Y") ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", @@ -186,27 +182,27 @@ lyt <- lyt %>% label_pos = "topleft", section_div = c(" "), nested = FALSE - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% + ) |> split_rows_by( "AEDECOD", split_label = "Preferred Term, n (%)", section_div = c(" "), nested = TRUE - ) %>% + ) |> summarize_row_groups( "AEDECOD", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% - analyze("AETOXGR2", afun = a_freq_j, extra_args = extra_args_1) %>% + ) |> + analyze("AETOXGR2", afun = a_freq_j, extra_args = extra_args_1) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -244,10 +240,10 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 23, 21) + +colwidth <- c(64, 21, 21, 21, 21) tt_to_tlgrtf( - colwidths = colwidth, result, file = fileid, orientation = "portrait", diff --git a/tests/testthat/source_code/tsfae22a.R b/tests/testthat/source_code/tsfae12a.R similarity index 81% rename from tests/testthat/source_code/tsfae22a.R rename to tests/testthat/source_code/tsfae12a.R index 4adcd56f..ee787a89 100644 --- a/tests/testthat/source_code/tsfae22a.R +++ b/tests/testthat/source_code/tsfae12a.R @@ -1,27 +1,3 @@ -############################################################################################### -## Original Reporting Effort: Standards -## Program Name: tsfae22a.R -## R Version: 4.2.1 -## junco Version: 1.0 -## Short Description: Program to create tsfae22a: TEAEs: SOC / PT by: Race -## Author: Johnson & Johnson Innovative Medicine -## Date: 18 Dec 2023 -## Input: ADSL, ADAE. -## Output: TSFAE22a.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting effort: -## Date: -## Description: -############################################################################################### - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -41,7 +17,7 @@ library(junco) # - Define column widths to help with desired page splitting ################################################################################ -tblid <- "TSFAE22a" +tblid <- "TSFAE12a" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -77,12 +53,32 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl), RACE) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, RACE) adsl$colspan_trt <- factor( @@ -100,23 +96,23 @@ colspan_trt_map <- create_colspan_map( ) # Add total for Race - adsl -totalrace1 <- adsl %>% - filter(RACE != "UNKNOWN" & !is.na(RACE)) %>% +totalrace1 <- adsl |> + filter(!RACE %in% c("UNKNOWN", "NOT REPORTED") & !is.na(RACE)) |> mutate(RACE = "Total") adsl <- bind_rows(totalrace1, adsl) -adsl <- adsl %>% +adsl <- adsl |> mutate( RACEcat = case_when( RACE == "Total" ~ "Total", RACE == "WHITE" ~ "White", RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black", RACE == "ASIAN" ~ "Asian", - RACE != "UNKNOWN" & !is.na(RACE) ~ "Other" + RACE == "OTHER" ~ "Other" ) - ) %>% - filter(RACEcat %in% c("Total", "White", "Black", "Asian", "Other")) %>% + ) |> + filter(RACEcat %in% c("Total", "White", "Black", "Asian", "Other")) |> select(-RACE) adsl$spanheader <- factor( @@ -130,23 +126,23 @@ adsl$RACEcat <- factor( ) # Add total for Race - adae -totalrace2 <- adae %>% - filter(RACE != "UNKNOWN" & !is.na(RACE)) %>% +totalrace2 <- adae |> + filter(!RACE %in% c("UNKNOWN", "NOT REPORTED") & !is.na(RACE)) |> mutate(RACE = "Total") adae <- bind_rows(totalrace2, adae) -adae <- adae %>% +adae <- adae |> mutate( RACEcat = case_when( RACE == "Total" ~ "Total", RACE == "WHITE" ~ "White", RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black", RACE == "ASIAN" ~ "Asian", - RACE != "UNKNOWN" & !is.na(RACE) ~ "Other" + RACE == "OTHER" ~ "Other" ) - ) %>% - filter(RACEcat %in% c("Total", "White", "Black", "Asian", "Other")) %>% + ) |> + filter(RACEcat %in% c("Total", "White", "Black", "Asian", "Other")) |> select(-RACE) adae$RACEcat <- factor( @@ -176,23 +172,23 @@ extra_args_2 <- list( lyt <- basic_table( top_level_section_div = " ", show_colcounts = FALSE -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% - split_cols_by("spanheader", split_fun = trim_levels_in_group("RACEcat")) %>% - split_cols_by("RACEcat") %>% +lyt <- lyt |> + split_cols_by("spanheader", split_fun = trim_levels_in_group("RACEcat")) |> + split_cols_by("RACEcat") |> analyze( popfl, afun = a_freq_j, @@ -206,7 +202,7 @@ lyt <- lyt %>% section_div = c(" ") ) ) - ) %>% + ) |> analyze( "TRTEMFL", afun = a_freq_j, @@ -219,7 +215,7 @@ lyt <- lyt %>% section_div = c(" ") ) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", @@ -227,16 +223,16 @@ lyt <- lyt %>% label_pos = "topleft", section_div = c(" "), nested = FALSE - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) %>% + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -293,10 +289,10 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 23, 21, 21, 19, 19, 19, 21, 21, 21, 19, 21, 21, 21, 19, 19, 19, 21) + +colwidth <- c(64, 21, 19, 19, 19, 19, 21, 21, 21, 21, 19, 21, 21, 19, 21, 19, 21, 19, 19, 19, 19) tt_to_tlgrtf( - colwidths = colwidth, result, file = fileid, orientation = "portrait", diff --git a/tests/testthat/source_code/tsfae22b.R b/tests/testthat/source_code/tsfae12b.R similarity index 80% rename from tests/testthat/source_code/tsfae22b.R rename to tests/testthat/source_code/tsfae12b.R index 07d2665e..f7420f1b 100644 --- a/tests/testthat/source_code/tsfae22b.R +++ b/tests/testthat/source_code/tsfae12b.R @@ -1,28 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae22b.R -## R version: 4.2.1 -## Short Description: TEAEs: SOC / PT by: Sex -## Author: Johnson & Johnson Innovative Medicine -## Date: 22 Jan 2024 -## Input: ADSL, ADAE. -## Output: TSFAE22b.rtf -## Remarks: Template R script version using rtables framework -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -42,7 +17,7 @@ library(junco) # - Define column widths to help with desired page splitting ################################################################################ -tblid <- "TSFAE22b" +tblid <- "TSFAE12b" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -78,12 +53,32 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl), SEX) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, SEX) adsl$colspan_trt <- factor( @@ -101,20 +96,20 @@ colspan_trt_map <- create_colspan_map( ) # Add total for Sex - adsl -totalsex1 <- adsl %>% +totalsex1 <- adsl |> mutate(SEX = "Total") adsl <- bind_rows(totalsex1, adsl) -adsl <- adsl %>% +adsl <- adsl |> mutate( SEXcat = case_when( SEX == "Total" ~ "Total", SEX == "M" ~ "Male", SEX == "F" ~ "Female" ) - ) %>% - filter(SEXcat %in% c("Total", "Male", "Female")) %>% + ) |> + filter(SEXcat %in% c("Total", "Male", "Female")) |> select(-SEX) adsl$spanheader <- factor( @@ -125,20 +120,20 @@ adsl$spanheader <- factor( adsl$SEXcat <- factor(adsl$SEXcat, levels = c("Total", "Male", "Female")) # Add total for Sex - adae -totalsex2 <- adae %>% +totalsex2 <- adae |> mutate(SEX = "Total") adae <- bind_rows(totalsex2, adae) -adae <- adae %>% +adae <- adae |> mutate( SEXcat = case_when( SEX == "Total" ~ "Total", SEX == "M" ~ "Male", SEX == "F" ~ "Female" ) - ) %>% - filter(SEXcat %in% c("Total", "Male", "Female")) %>% + ) |> + filter(SEXcat %in% c("Total", "Male", "Female")) |> select(-SEX) adae$SEXcat <- factor(adae$SEXcat, levels = c("Total", "Male", "Female")) @@ -164,23 +159,23 @@ extra_args_2 <- list( lyt <- basic_table( top_level_section_div = " ", show_colcounts = FALSE -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% - split_cols_by("spanheader", split_fun = trim_levels_in_group("SEXcat")) %>% - split_cols_by("SEXcat") %>% +lyt <- lyt |> + split_cols_by("spanheader", split_fun = trim_levels_in_group("SEXcat")) |> + split_cols_by("SEXcat") |> analyze( popfl, afun = a_freq_j, @@ -193,7 +188,7 @@ lyt <- lyt %>% val = "Y" ) ) - ) %>% + ) |> analyze( "TRTEMFL", afun = a_freq_j, @@ -205,7 +200,7 @@ lyt <- lyt %>% val = "Y" ) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", @@ -213,16 +208,16 @@ lyt <- lyt %>% label_pos = "topleft", section_div = c(" "), nested = FALSE - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) %>% + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -279,10 +274,10 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 21, 21, 21, 23, 21, 21, 21, 21, 21) + +colwidth <- c(64, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21) tt_to_tlgrtf( - colwidths = colwidth, result, file = fileid, orientation = "portrait", diff --git a/tests/testthat/source_code/tsfae22c.R b/tests/testthat/source_code/tsfae12c.R similarity index 81% rename from tests/testthat/source_code/tsfae22c.R rename to tests/testthat/source_code/tsfae12c.R index 567b7241..7b4c173c 100644 --- a/tests/testthat/source_code/tsfae22c.R +++ b/tests/testthat/source_code/tsfae12c.R @@ -1,28 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae22c.R -## R version: 4.2.1 -## Short Description: TEAEs: SOC / PT by: AGE -## Author: Johnson & Johnson Innovative Medicine -## Date: 22 Jan 2024 -## Input: ADSL, ADAE. -## Output: TSFAE22c.rtf -## Remarks: Template R script version using rtables framework -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -43,7 +18,7 @@ library(junco) # - Define column widths to help with desired page splitting ################################################################################ -tblid <- "TSFAE22c" +tblid <- "TSFAE12c" fileid <- write_path(opath, tblid) tab_titles <- list( title = "Dummy Title", @@ -81,17 +56,37 @@ if (combined_colspan_trt == TRUE) { ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl), all_of(agegrpvar)) -adsl_levels <- adsl %>% +adsl_levels <- adsl |> filter(!is.na(!!rlang::sym(agegrpvar))) agelevels <- c("Total", levels(adsl_levels[[agegrpvar]])) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, all_of(agegrpvar)) adsl$colspan_trt <- factor( @@ -109,12 +104,12 @@ colspan_trt_map <- create_colspan_map( ) # Add total for Age - adsl -totalage1 <- adsl %>% +totalage1 <- adsl |> mutate(!!agegrpvar := "Total") adsl <- bind_rows(totalage1, adsl) -adsl <- adsl %>% +adsl <- adsl |> filter(!!rlang::sym(agegrpvar) %in% agelevels) adsl$spanheader <- factor( @@ -125,12 +120,12 @@ adsl$spanheader <- factor( adsl[[agegrpvar]] <- factor(adsl[[agegrpvar]], levels = agelevels) # Add total for Age - adae -totalage2 <- adae %>% +totalage2 <- adae |> mutate(!!agegrpvar := "Total") adae <- bind_rows(totalage2, adae) -adae <- adae %>% +adae <- adae |> filter(!!rlang::sym(agegrpvar) %in% agelevels) adae[[agegrpvar]] <- factor(adae[[agegrpvar]], levels = agelevels) @@ -156,23 +151,23 @@ extra_args_2 <- list( lyt <- basic_table( top_level_section_div = " ", show_colcounts = FALSE -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% - split_cols_by("spanheader", split_fun = trim_levels_in_group(agegrpvar)) %>% - split_cols_by(agegrpvar) %>% +lyt <- lyt |> + split_cols_by("spanheader", split_fun = trim_levels_in_group(agegrpvar)) |> + split_cols_by(agegrpvar) |> analyze( popfl, afun = a_freq_j, @@ -185,7 +180,7 @@ lyt <- lyt %>% val = "Y" ) ) - ) %>% + ) |> analyze( "TRTEMFL", afun = a_freq_j, @@ -197,7 +192,7 @@ lyt <- lyt %>% val = "Y" ) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", @@ -205,16 +200,16 @@ lyt <- lyt %>% label_pos = "topleft", section_div = c(" "), nested = FALSE - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% - analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) %>% + ) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, ae, alt_counts_df = adsl) +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on chosen active treatment columns. @@ -271,10 +266,10 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 23, 21, 21, 21, 21, 23, 23, 21, 21, 21, 19, 21, 21) + +colwidth <- c(64, 21, 21, 21, 21, 21, 19, 21, 21, 21, 21, 21, 21, 21, 19, 19, 21) tt_to_tlgrtf( - colwidths = colwidth, result, file = fileid, orientation = "portrait", diff --git a/tests/testthat/source_code/tsfae12d.R b/tests/testthat/source_code/tsfae12d.R new file mode 100644 index 00000000..f1a16826 --- /dev/null +++ b/tests/testthat/source_code/tsfae12d.R @@ -0,0 +1,211 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) +library(stringr) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFAE12d" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +trtvar <- "TRT01A" +popfl <- "SAFFL" +combined_colspan_trt <- TRUE +risk_diff <- FALSE +rr_method <- "wald" +ctrl_grp <- "Placebo" + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +################################################################################ +# Process Data: +################################################################################ + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ), + AERELTOT = ifelse(AEREL %in% c("RELATED", "NOT RELATED"), stringr::str_to_title(AEREL), NA) + ) |> + filter(TRTEMFL == "Y" & !is.na(AERELTOT)) |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AEREL, AERELTOT) + +adaetot <- adae |> + mutate( + AERELTOT = "Total" + ) + +adaeall <- bind_rows(adae, adaetot) |> + mutate(AERELTOT = factor(as.character(AERELTOT), levels = c("Total", "Not Related", "Related"))) + + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +# join data together +ae <- adaeall |> inner_join(adsl, by = c("USUBJID")) + +ae$spanheader <- factor(ifelse(ae$AERELTOT == "Total", " ", "Relationship"), levels = c(" ", "Relationship")) + +adsl1 <- adsl |> + mutate(AERELTOT = "Total") + +adsl <- adsl1 |> + mutate(AERELTOT = factor(as.character(AERELTOT), levels = c("Total", "Not Related", "Related"))) +adsl$spanheader <- factor(ifelse(adsl$AERELTOT == "Total", " ", "Relationship"), levels = c(" ", "Relationship")) + + +if (risk_diff == TRUE) { + adsl$rrisk_header <- "Risk Difference (%) (95% CI)" + adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) +} + + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +################################################################################ +# Define layout and build table: +################################################################################ + +extra_args_1 <- list( + denom = "N_colgroup", + riskdiff = FALSE, + .stats = c("count_unique_fraction"), + colgroup = trtvar, + ref_path = ref_path +) + + +lyt <- basic_table( + top_level_section_div = " ", + colcount_format = "N=xx" +) |> + split_cols_by("colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map)) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit, show_colcounts = TRUE) +} else { + lyt <- lyt |> + split_cols_by(trtvar, show_colcounts = TRUE) +} + +lyt <- lyt |> + split_cols_by("spanheader", split_fun = trim_levels_in_group("AERELTOT")) |> + split_cols_by("AERELTOT", show_colcounts = FALSE) |> + analyze( + "TRTEMFL", + afun = a_freq_j, + show_labels = "hidden", + extra_args = append(extra_args_1, list(label = "Subjects with >=1 AE", val = "Y")) + ) |> + split_rows_by( + "AEBODSYS", + split_label = "System Organ Class", + split_fun = trim_levels_in_group("AEDECOD"), + label_pos = "topleft", + section_div = c(" "), + nested = FALSE + ) |> + summarize_row_groups("AEBODSYS", cfun = a_freq_j, extra_args = extra_args_1) |> + analyze("AEDECOD", afun = a_freq_j, extra_args = extra_args_1) |> + append_topleft(" Preferred Term, n (%)") + + +result <- build_table(lyt, ae, alt_counts_df = adsl, round_type = "sas") + +if (length(adae$TRTEMFL) != 0) { + result <- sort_at_path( + result, + c("root", "AEBODSYS"), + scorefun = jj_complex_scorefun( + colpath = c("colspan_trt", "Active Study Agent", trtvar, "Combined", "spanheader", " ", "AERELTOT", "Total") + ) + ) + result <- sort_at_path( + result, + c("root", "AEBODSYS", "*", "AEDECOD"), + scorefun = jj_complex_scorefun( + colpath = c("colspan_trt", "Active Study Agent", trtvar, "Combined", "spanheader", " ", "AERELTOT", "Total") + ) + ) +} + +################################################################################ +## Remove the N=xx column headers for the risk difference columns +################################################################################ + +result <- remove_col_count(result) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae13.R b/tests/testthat/source_code/tsfae13.R deleted file mode 100644 index 7e0cf21c..00000000 --- a/tests/testthat/source_code/tsfae13.R +++ /dev/null @@ -1,162 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae13.R -## R version: 4.2.1 -## Short Description: Program to create tsfae13: Exposure-adjusted Incidence -## Rate Analysis by Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 15FEB2024 -## Input: adsl.RDS, adae.RDS -## Output: tsfae13.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFAE13" -fileid <- write_path(opath, tblid) -popfl <- "SAFFL" -trtvar <- "TRT01A" -ctrl_grp <- "Placebo" -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - - -################################################################################ -# Process data: -################################################################################ - -adexsum <- adexsum_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & PARAMCD == "TRTDURY") %>% - create_colspan_var( - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar - ) %>% - mutate( - rrisk_header = "Risk Difference (95% CI)", - rrisk_label = paste(!!rlang::sym(trtvar), "vs", ctrl_grp), - TRTDURY = AVAL - ) %>% - select( - USUBJID, - !!rlang::sym(trtvar), - colspan_trt, - rrisk_header, - rrisk_label, - TRTDURY - ) - -adae <- adae_jnj %>% - filter(TRTEMFL == "Y" & AOCCPFL == "Y") %>% - select(USUBJID, AEDECOD, ASTDY, AOCCPFL) - -# join -- -- subjects without ae will be handled via alt_counts_df dataframe -aefup <- right_join(adae, adexsum, by = "USUBJID") - -colspan_trt_map <- create_colspan_map( - adexsum, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - -################################################################################ -# Define layout and build table: -################################################################################ - -lyt <- basic_table( - show_colcounts = TRUE, - colcount_format = "N=xx", - top_level_section_div = " " -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels(ctrl_grp) - ) %>% - analyze( - "TRTDURY", - nested = FALSE, - show_labels = "hidden", - afun = a_patyrs_j, - extra_args = list(.labels = c(patyrs = "Subject years~[super a]")) - ) %>% - analyze( - vars = "AEDECOD", - nested = FALSE, - afun = a_eair100_j, - extra_args = list( - fup_var = "TRTDURY", - occ_var = "AOCCPFL", - occ_dy = "ASTDY", - ref_path = ref_path, - drop_levels = TRUE, - row_labels_adj = TRUE - ) - ) %>% - append_topleft("Preferred Term, EAIR Per 100 SY") - - -result <- build_table(lyt, aefup, alt_counts_df = adexsum) - - -################################################################################ -# Post-Processing: -# - Remove Ns from Risk cols -# - Sort by descending AEDECOD in the combined Xanomeline High Dose column -################################################################################ -result <- result %>% - sort_at_path( - path = c("AEDECOD"), - scorefun = jj_complex_scorefun(colpath = "Xanomeline High Dose") - ) - -result <- remove_col_count(result) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table: -################################################################################ - -colwidth <- c(64, 10, 12, 10, 35, 37) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae23a.R b/tests/testthat/source_code/tsfae13a.R similarity index 77% rename from tests/testthat/source_code/tsfae23a.R rename to tests/testthat/source_code/tsfae13a.R index 182fd343..61f0a074 100644 --- a/tests/testthat/source_code/tsfae23a.R +++ b/tests/testthat/source_code/tsfae13a.R @@ -1,30 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: tsfae23a.R -## R Version: 4.2.1 -## Short Description: Create TSFAE23A: Subjects With -## Related Treatment-emergent Serious Adverse Events -## by Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 23Feb2024 -## Input: ADAE, ADSL -## Output: tsfae23a.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -35,7 +8,7 @@ library(junco) # Define script level parameters ############################################################################### -tblid <- "TSFAE23a" +tblid <- "TSFAE13a" fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" @@ -77,15 +50,25 @@ if (combined_colspan_trt == TRUE) { # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> create_colspan_var( non_active_grp = c("Placebo"), non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% + ) |> select( STUDYID, USUBJID, @@ -104,17 +87,23 @@ trt_map <- create_colspan_map( ) ref_path <- c("colspan_trt", " ", trtvar, "Placebo") -adae0 <- adae_jnj %>% +adae0 <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> filter( !!rlang::sym(popfl) == "Y" & !!rlang::sym(aerelvar) == "RELATED" & TRTEMFL == "Y" & AESER == "Y" - ) %>% + ) |> left_join( subset(adsl, select = c("STUDYID", "USUBJID", "colspan_trt")), by = c("STUDYID", "USUBJID") - ) %>% + ) |> select( STUDYID, USUBJID, @@ -128,13 +117,25 @@ adae0 <- adae_jnj %>% ) if (nrow(adae0) == 0) { - adae <- adae0 %>% - select(STUDYID, USUBJID, TRTEMFL, AEDECOD) %>% + adae <- adae0 |> + select(STUDYID, USUBJID, TRTEMFL, AEDECOD) |> right_join(adsl, by = c("STUDYID", "USUBJID")) } else { adae <- adae0 } +adae <- adae |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + ############################################################################### # Define layout and build table ############################################################################### @@ -143,18 +144,18 @@ lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx", top_level_section_div = " " -) %>% +) |> split_cols_by("colspan_trt", split_fun = trim_levels_to_map(map = trt_map)) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> analyze( vars = "TRTEMFL", show_labels = "hidden", @@ -168,21 +169,21 @@ lyt <- lyt %>% ) if (nrow(adae0) > 0) { - lyt <- lyt %>% + lyt <- lyt |> count_occurrences( vars = "AEDECOD", .stats = c("count_fraction_fixed_dp"), .indent_mods = c(count_fraction = -1L), .formats = c("count_fraction_fixed_dp" = jjcsformat_count_fraction), nested = FALSE - ) %>% + ) |> append_topleft("Preferred Term, n (%)") } else { - lyt <- lyt %>% + lyt <- lyt |> append_topleft("Preferred Term, n (%)") } -result <- build_table(lyt, df = adae, alt_counts_df = adsl) +result <- build_table(lyt, df = adae, alt_counts_df = adsl, round_type = "sas") ############################################################################### # Post-processing @@ -219,6 +220,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ############################################################################### -colwidth <- c(64, 17, 17, 19, 19) + +colwidth <- c(50, 21, 21, 21, 21) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfae23b.R b/tests/testthat/source_code/tsfae13b.R similarity index 74% rename from tests/testthat/source_code/tsfae23b.R rename to tests/testthat/source_code/tsfae13b.R index 8b426e3a..4e45419b 100644 --- a/tests/testthat/source_code/tsfae23b.R +++ b/tests/testthat/source_code/tsfae13b.R @@ -1,30 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: tsfae23b.R -## R Version: 4.2.1 -## Short Description: Create TSFAE23B: Subjects With Related Fatal -## Treatment-emergent Adverse Events by Preferred -## Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 23Feb2024 -## Input: ADAE, ADSL -## Output: tsfae23b.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -35,7 +8,7 @@ library(junco) # Define script level parameters ############################################################################### -tblid <- "TSFAE23b" +tblid <- "TSFAE13b" fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" @@ -77,15 +50,25 @@ if (combined_colspan_trt == TRUE) { # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> create_colspan_var( non_active_grp = c("Placebo"), non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% + ) |> select( STUDYID, USUBJID, @@ -104,17 +87,23 @@ trt_map <- create_colspan_map( ) ref_path <- c("colspan_trt", " ", trtvar, "Placebo") -adae0 <- adae_jnj %>% +adae0 <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> filter( !!rlang::sym(popfl) == "Y" & !!rlang::sym(aerelvar) == "RELATED" & TRTEMFL == "Y" & AEOUT == "FATAL" - ) %>% + ) |> left_join( subset(adsl, select = c("STUDYID", "USUBJID", "colspan_trt")), by = c("STUDYID", "USUBJID") - ) %>% + ) |> select( STUDYID, USUBJID, @@ -128,13 +117,25 @@ adae0 <- adae_jnj %>% ) if (nrow(adae0) == 0) { - adae <- adae0 %>% - select(STUDYID, USUBJID, TRTEMFL, AEDECOD) %>% + adae <- adae0 |> + select(STUDYID, USUBJID, TRTEMFL, AEDECOD) |> right_join(adsl, by = c("STUDYID", "USUBJID")) } else { adae <- adae0 } +adae <- adae |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + ############################################################################### # Define layout and build table ############################################################################### @@ -143,18 +144,18 @@ lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx", top_level_section_div = " " -) %>% +) |> split_cols_by("colspan_trt", split_fun = trim_levels_to_map(map = trt_map)) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> analyze( vars = "TRTEMFL", show_labels = "hidden", @@ -168,21 +169,21 @@ lyt <- lyt %>% ) if (nrow(adae0) > 0) { - lyt <- lyt %>% + lyt <- lyt |> count_occurrences( vars = "AEDECOD", .stats = c("count_fraction_fixed_dp"), .indent_mods = c(count_fraction = -1L), .formats = c("count_fraction_fixed_dp" = jjcsformat_count_fraction), nested = FALSE - ) %>% + ) |> append_topleft("Preferred Term, n (%)") } else { - lyt <- lyt %>% + lyt <- lyt |> append_topleft("Preferred Term, n (%)") } -result <- build_table(lyt, df = adae, alt_counts_df = adsl) +result <- build_table(lyt, df = adae, alt_counts_df = adsl, round_type = "sas") ############################################################################### # Post-processing @@ -201,16 +202,6 @@ if (nrow(adae0) > 0) { ) } -if (nrow(adae0) == 0) { - # Post-Processing step to remove 'Subjects with' row - result <- safe_prune_table( - result, - prune_func = remove_rows( - removerowtext = "Subjects with >=1 related fatal AE" - ) - ) -} - ############################################################################### # Retrieve titles and footnotes ############################################################################### @@ -221,6 +212,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ############################################################################### -colwidth <- c(41, 4, 4, 4, 4) + +colwidth <- c(56, 5, 5, 5, 17) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfae23c.R b/tests/testthat/source_code/tsfae13c.R similarity index 76% rename from tests/testthat/source_code/tsfae23c.R rename to tests/testthat/source_code/tsfae13c.R index 33d21aaf..dbed2efe 100644 --- a/tests/testthat/source_code/tsfae23c.R +++ b/tests/testthat/source_code/tsfae13c.R @@ -1,31 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: tsfae23c.R -## R Version: 4.2.1 -## Short Description: Create: TSFAE23C: Subjects With Related -## Treatment-emergent Adverse Events Leading to -## Discontinuation of Study Treatment by Preferred -## Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 23Feb2024 -## Input: ADAE, ADSL -## Output: tsfae23c.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -36,7 +8,7 @@ library(junco) # Define script level parameters ############################################################################### -tblid <- "TSFAE23c" +tblid <- "TSFAE13c" fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" @@ -78,15 +50,25 @@ if (combined_colspan_trt == TRUE) { # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> create_colspan_var( non_active_grp = c("Placebo"), non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% + ) |> select( STUDYID, USUBJID, @@ -105,17 +87,23 @@ trt_map <- create_colspan_map( ) ref_path <- c("colspan_trt", " ", trtvar, "Placebo") -adae0 <- adae_jnj %>% +adae0 <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> filter( !!rlang::sym(popfl) == "Y" & !!rlang::sym(aerelvar) == "RELATED" & TRTEMFL == "Y" & AEACN == "DRUG WITHDRAWN" - ) %>% + ) |> left_join( subset(adsl, select = c("STUDYID", "USUBJID", "colspan_trt")), by = c("STUDYID", "USUBJID") - ) %>% + ) |> select( STUDYID, USUBJID, @@ -129,13 +117,25 @@ adae0 <- adae_jnj %>% ) if (nrow(adae0) == 0) { - adae <- adae0 %>% - select(STUDYID, USUBJID, TRTEMFL, AEDECOD) %>% + adae <- adae0 |> + select(STUDYID, USUBJID, TRTEMFL, AEDECOD) |> right_join(adsl, by = c("STUDYID", "USUBJID")) } else { adae <- adae0 } +adae <- adae |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + ############################################################################### # Define layout and build table ############################################################################### @@ -144,18 +144,18 @@ lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx", top_level_section_div = " " -) %>% +) |> split_cols_by("colspan_trt", split_fun = trim_levels_to_map(map = trt_map)) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> analyze( vars = "TRTEMFL", show_labels = "hidden", @@ -169,21 +169,21 @@ lyt <- lyt %>% ) if (nrow(adae0) > 0) { - lyt <- lyt %>% + lyt <- lyt |> count_occurrences( vars = "AEDECOD", .stats = c("count_fraction_fixed_dp"), .indent_mods = c(count_fraction = -1L), .formats = c("count_fraction_fixed_dp" = jjcsformat_count_fraction), nested = FALSE - ) %>% + ) |> append_topleft("Preferred Term, n (%)") } else { - lyt <- lyt %>% + lyt <- lyt |> append_topleft("Preferred Term, n (%)") } -result <- build_table(lyt, df = adae, alt_counts_df = adsl) +result <- build_table(lyt, df = adae, alt_counts_df = adsl, round_type = "sas") ############################################################################### # Post-processing @@ -222,6 +222,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ############################################################################### -colwidth <- c(64, 17, 17, 17, 17) + +colwidth <- c(64, 21, 21, 21, 19) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfae23d.R b/tests/testthat/source_code/tsfae13d.R similarity index 77% rename from tests/testthat/source_code/tsfae23d.R rename to tests/testthat/source_code/tsfae13d.R index 57f1b291..c7a5dcfb 100644 --- a/tests/testthat/source_code/tsfae23d.R +++ b/tests/testthat/source_code/tsfae13d.R @@ -1,30 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: tsfae23d.R -## R Version: 4.2.1 -## Short Description: Create TSFAE23D: Subjects With Related -## Non-serious Treatment-emergent Adverse Events by -## Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 23Feb2024 -## Input: ADAE, ADSL -## Output: tsfae23d.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -35,7 +8,7 @@ library(junco) # Define script level parameters ############################################################################### -tblid <- "TSFAE23d" +tblid <- "TSFAE13d" fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" @@ -77,15 +50,25 @@ if (combined_colspan_trt == TRUE) { # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> create_colspan_var( non_active_grp = c("Placebo"), non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% + ) |> select( STUDYID, USUBJID, @@ -104,17 +87,23 @@ trt_map <- create_colspan_map( ) ref_path <- c("colspan_trt", " ", trtvar, "Placebo") -adae0 <- adae_jnj %>% +adae0 <- adae_jnj |> + mutate( + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> filter( !!rlang::sym(popfl) == "Y" & !!rlang::sym(aerelvar) == "RELATED" & TRTEMFL == "Y" & AESER == "N" - ) %>% + ) |> left_join( subset(adsl, select = c("STUDYID", "USUBJID", "colspan_trt")), by = c("STUDYID", "USUBJID") - ) %>% + ) |> select( STUDYID, USUBJID, @@ -128,13 +117,25 @@ adae0 <- adae_jnj %>% ) if (nrow(adae0) == 0) { - adae <- adae0 %>% - select(STUDYID, USUBJID, TRTEMFL, AEDECOD) %>% + adae <- adae0 |> + select(STUDYID, USUBJID, TRTEMFL, AEDECOD) |> right_join(adsl, by = c("STUDYID", "USUBJID")) } else { adae <- adae0 } +adae <- adae |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + ############################################################################### # Define layout and build table ############################################################################### @@ -143,18 +144,18 @@ lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx", top_level_section_div = " " -) %>% +) |> split_cols_by("colspan_trt", split_fun = trim_levels_to_map(map = trt_map)) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> analyze( vars = "TRTEMFL", show_labels = "hidden", @@ -168,21 +169,21 @@ lyt <- lyt %>% ) if (nrow(adae0) > 0) { - lyt <- lyt %>% + lyt <- lyt |> count_occurrences( vars = "AEDECOD", .stats = c("count_fraction_fixed_dp"), .indent_mods = c(count_fraction = -1L), .formats = c("count_fraction_fixed_dp" = jjcsformat_count_fraction), nested = FALSE - ) %>% + ) |> append_topleft("Preferred Term, n (%)") } else { - lyt <- lyt %>% + lyt <- lyt |> append_topleft("Preferred Term, n (%)") } -result <- build_table(lyt, df = adae, alt_counts_df = adsl) +result <- build_table(lyt, df = adae, alt_counts_df = adsl, round_type = "sas") ############################################################################### # Post-processing @@ -221,6 +222,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ############################################################################### -colwidth <- c(64, 21, 17, 21, 19) + +colwidth <- c(64, 21, 21, 21, 21) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfae15.R b/tests/testthat/source_code/tsfae15.R deleted file mode 100644 index 45413ea9..00000000 --- a/tests/testthat/source_code/tsfae15.R +++ /dev/null @@ -1,218 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae15.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Adverse Events Leading -## to Discontinuation of Study Treatment by Organ System -## and OCMQ (Narrow) -## Author: Johnson & Johnson Innovative Medicine -## Date: 2025-07-21 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE15.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored cpct_relrisk_fact to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE15" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" -combined_colspan_trt <- TRUE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adae <- adaeocmq_jnj %>% - filter(TRTEMFL == "Y" & TRDISCFL == "Y" & OCMQCLSS == "Narrow") %>% - select(USUBJID, TRTEMFL, OCMQSOC, OCMQNAM) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) -} - -# join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) -} - -lyt <- lyt %>% - split_rows_by( - "OCMQSOC", - split_label = "Organ System~[super a]", - split_fun = trim_levels_in_group("OCMQNAM"), - label_pos = "topleft", - section_div = c(" "), - nested = FALSE - ) %>% - summarize_row_groups( - "OCMQSOC", - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - analyze( - "OCMQNAM", - afun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - append_topleft(" OCMQ (Narrow), n (%)") - -result <- build_table(lyt, ae, alt_counts_df = adsl) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - result <- sort_at_path( - result, - c("root", "OCMQSOC"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("root", "OCMQSOC", "*", "OCMQNAM"), - scorefun = jj_complex_scorefun() - ) -} - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 19, 17, 21, 17, 31, 31) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae16.R b/tests/testthat/source_code/tsfae16.R deleted file mode 100644 index 951fc20d..00000000 --- a/tests/testthat/source_code/tsfae16.R +++ /dev/null @@ -1,268 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae16.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Adverse Events by System -## Organ Class and FDA Medical Query (Broad and Narrow) -## Author: Johnson & Johnson Innovative Medicine -## Date: 30 Apr 2025 -## Input: ADSL, ADAEFMQ -## Output: TSFAE16.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored cpct_relrisk_fact to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE16" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" - -combined_colspan_trt <- FALSE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -QVAR_CLASS <- "OCMQCLSS" -QVAR_SOC <- "OCMQSOC" -QVAR_NAM <- "OCMQNAM" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for ref group - rm_combo_from_ref <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_ref)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adsl0 <- adsl - -adsl <- rbind( - adsl0 %>% mutate(!!rlang::sym(QVAR_CLASS) := "Narrow"), - adsl0 %>% mutate(!!rlang::sym(QVAR_CLASS) := "Broad") -) -### label slightly differs from values in dataset -QVAR_CLASS2 <- "OCMQCLS2" -adsl[[QVAR_CLASS2]] <- paste(adsl[[QVAR_CLASS]], "OCMQs") - -adae <- adaeocmq_jnj %>% - filter(TRTEMFL == "Y") %>% - select(USUBJID, TRTEMFL, all_of(c(QVAR_CLASS, QVAR_NAM, QVAR_SOC))) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -# join data together -ae <- adae %>% inner_join(., adsl) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -if (risk_diff) { - ## risk difference columns are created by this split function for FMQ table - # to get risk diff column within FMQclass - mysplfun1 <- make_split_fun( - post = list( - add_combo_facet( - "RR_difference", - label = "Risk Difference (%) (95% CI)", - levels = c("Active Study Agent") - ) - ) - ) -} else { - mysplfun1 <- NULL -} - -# further split process to ensure only the required treatment columns remain in the layout -make_cond_rm_from_map <- function(map, diff_rm = "Placebo") { - outer_levs <- unique(map[[1]]) - fnlst <- list() - for (i in seq_along(outer_levs)) { - inner_levs <- map[map[[1]] == outer_levs[[i]], 2, drop = TRUE] - fnlst[[i]] <- cond_rm_facets( - facets = inner_levs, - ancestor_pos = -1, - value = outer_levs[i], - keep_matches = TRUE - ) - } - - # remove ref group column within RR columns - rr_rm_cond <- cond_rm_facets( - facets = diff_rm, - ancestor_pos = -1, - value = "RR_difference", - keep_matches = FALSE - ) - - # update label in risk diff column to include diff from reference in label - post_relabel <- function(splres, spl, fulldf, .spl_context) { - inrr <- grepl("difference", tail(.spl_context$value, 1)) - if (inrr) { - splres$labels <- paste(splres$labels, "vs", diff_rm) - } - splres - } - - make_split_fun(post = c(fnlst, rr_rm_cond, post_relabel)) -} - -cond_trt_splfun <- make_cond_rm_from_map(colspan_trt_map, diff_rm = ctrl_grp) - -################################################################################ -# Define layout and build table: -################################################################################ - -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - colgroup = "OCMQCLSS", - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by(QVAR_CLASS, labels_var = QVAR_CLASS2) %>% - split_cols_by("colspan_trt", split_fun = mysplfun1) %>% - split_cols_by(trtvar, split_fun = cond_trt_splfun) - -lyt <- lyt %>% - split_rows_by( - QVAR_SOC, - split_label = "Organ System Class", - split_fun = trim_levels_in_group(QVAR_NAM), - label_pos = "topleft", - section_div = c(" ") - ) %>% - summarize_row_groups( - QVAR_SOC, - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - analyze( - QVAR_NAM, - afun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - append_topleft(" OCMQ, n (%)") - -result <- build_table(lyt, ae, alt_counts_df = adsl) - - -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - # per guidance of DAS : sorting should be in Broad category - # this can be achieved by specifying colpath in jj_complex_scorefun - # see colpath argument -- category Broad is specified here - # this will result in sorting according first number of first column in Broad category - # ie sorting on decreasing frequency in Apa group in Broad category - # you can be more specific (eg specific single column) if you further specify the colpath to trial needs - cur_scorefun <- jj_complex_scorefun( - colpath = c(QVAR_CLASS, "Broad") - ) - - result <- sort_at_path(result, c(QVAR_SOC), scorefun = cur_scorefun) - result <- sort_at_path( - result, - c(QVAR_SOC, "*", QVAR_NAM), - scorefun = cur_scorefun - ) -} - -## Remove the N=xx column headers for the risk difference columns -### need to look at non-default level in the col_paths of the table - here at lvl 4 rather than 1 -result <- remove_col_count(result, span_label_var = "RR_difference") - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 21, 21, 21, 33, 31, 21, 21, 21, 33, 35) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae17a.R b/tests/testthat/source_code/tsfae17a.R deleted file mode 100644 index f0c43102..00000000 --- a/tests/testthat/source_code/tsfae17a.R +++ /dev/null @@ -1,243 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae17a.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Serious Adverse Events -## by Organ System, OCMQ (Narrow) and Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 2025-07-21 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE17a.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored cpct_relrisk_fact to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Define OCMQ Class used (default=Narrow) -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE17a" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - - -trtvar <- "TRT01A" -popfl <- "SAFFL" -ocmqclass <- "Narrow" -combined_colspan_trt <- TRUE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adae_full <- adaeocmq_jnj %>% - filter(TRTEMFL == "Y" & AESER == "Y" & OCMQCLSS == ocmqclass) %>% - select(USUBJID, TRTEMFL, OCMQSOC, OCMQNAM, AEDECOD) - -adae <- adae_full %>% - group_by(OCMQSOC) %>% - slice(1) %>% - ungroup() - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) -} - -# join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) -} - -lyt <- lyt %>% - split_rows_by( - "OCMQSOC", - split_label = "Organ System~[super a]", - split_fun = trim_levels_in_group("OCMQNAM"), - label_pos = "topleft", - section_div = c(" "), - nested = FALSE - ) %>% - summarize_row_groups( - "OCMQSOC", - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - split_rows_by( - "OCMQNAM", - split_label = paste0("OCMQ (", ocmqclass, ")"), - split_fun = trim_levels_in_group("AEDECOD"), - label_pos = "topleft", - nested = TRUE - ) %>% - summarize_row_groups( - "OCMQNAM", - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, ae, alt_counts_df = adsl) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - result <- sort_at_path( - result, - c("root", "OCMQSOC"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("root", "OCMQSOC", "*", "OCMQNAM"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("root", "OCMQSOC", "*", "OCMQNAM", "*", "AEDECOD"), - scorefun = jj_complex_scorefun() - ) -} - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 17, 17, 17, 17, 29, 29) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae17b.R b/tests/testthat/source_code/tsfae17b.R deleted file mode 100644 index 29cf8320..00000000 --- a/tests/testthat/source_code/tsfae17b.R +++ /dev/null @@ -1,242 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae17b.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Adverse Events Leading -## to Discontinuation of Study Treatment by Organ System, -## OCMQ (Narrow) and Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 2025-07-21 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE17b.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored cpct_relrisk_fact to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Define OCMQ Class used (default=Narrow) -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE17b" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" -ocmqclass <- "Narrow" -combined_colspan_trt <- TRUE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adae_full <- adaeocmq_jnj %>% - filter(TRTEMFL == "Y" & TRDISCFL == "Y" & OCMQCLSS == ocmqclass) %>% - select(USUBJID, TRTEMFL, OCMQSOC, OCMQNAM, AEDECOD) - -adae <- adae_full %>% - group_by(OCMQSOC) %>% - slice(1) %>% - ungroup() - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) -} - -# join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) -} - -lyt <- lyt %>% - split_rows_by( - "OCMQSOC", - split_label = "Organ System~[super a]", - split_fun = trim_levels_in_group("OCMQNAM"), - label_pos = "topleft", - section_div = c(" "), - nested = FALSE - ) %>% - summarize_row_groups( - "OCMQSOC", - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - split_rows_by( - "OCMQNAM", - split_label = paste0("OCMQ (", ocmqclass, ")"), - split_fun = trim_levels_in_group("AEDECOD"), - label_pos = "topleft", - nested = TRUE - ) %>% - summarize_row_groups( - "OCMQNAM", - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, ae, alt_counts_df = adsl) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - result <- sort_at_path( - result, - c("root", "OCMQSOC"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("root", "OCMQSOC", "*", "OCMQNAM"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("root", "OCMQSOC", "*", "OCMQNAM", "*", "AEDECOD"), - scorefun = jj_complex_scorefun() - ) -} - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 17, 17, 17, 17, 29, 29) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae17c.R b/tests/testthat/source_code/tsfae17c.R deleted file mode 100644 index 967bbde5..00000000 --- a/tests/testthat/source_code/tsfae17c.R +++ /dev/null @@ -1,241 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae17c.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Adverse Events by Organ -## System, OCMQ (Narrow) and Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 2025-07-21 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE17c.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored cpct_relrisk_fact to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Define OCMQ Class used (default=Narrow) -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE17c" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" -ocmqclass <- "Narrow" -combined_colspan_trt <- TRUE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adae_full <- adaeocmq_jnj %>% - filter(TRTEMFL == "Y" & OCMQCLSS == ocmqclass) %>% - select(USUBJID, TRTEMFL, OCMQSOC, OCMQNAM, AEDECOD) - -adae <- adae_full %>% - group_by(OCMQSOC) %>% - slice(1) %>% - ungroup() - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) -} - -# join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) -} - -lyt <- lyt %>% - split_rows_by( - "OCMQSOC", - split_label = "Organ System~[super a]", - split_fun = trim_levels_in_group("OCMQNAM"), - label_pos = "topleft", - section_div = c(" "), - nested = FALSE - ) %>% - summarize_row_groups( - "OCMQSOC", - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - split_rows_by( - "OCMQNAM", - split_label = paste0("OCMQ (", ocmqclass, ")"), - split_fun = trim_levels_in_group("AEDECOD"), - label_pos = "topleft", - nested = TRUE - ) %>% - summarize_row_groups( - "OCMQNAM", - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, ae, alt_counts_df = adsl) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - result <- sort_at_path( - result, - c("root", "OCMQSOC"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("root", "OCMQSOC", "*", "OCMQNAM"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("root", "OCMQSOC", "*", "OCMQNAM", "*", "AEDECOD"), - scorefun = jj_complex_scorefun() - ) -} - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 17, 17, 17, 17, 29, 29) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae17d.R b/tests/testthat/source_code/tsfae17d.R deleted file mode 100644 index 74903a96..00000000 --- a/tests/testthat/source_code/tsfae17d.R +++ /dev/null @@ -1,241 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae17d.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Adverse Events by Organ -## System, OCMQ (Broad) and Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 2025-07-21 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE17d.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored cpct_relrisk_fact to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Define OCMQ Class used (default=Narrow) -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE17d" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" -ocmqclass <- "Broad" -combined_colspan_trt <- TRUE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adae_full <- adaeocmq_jnj %>% - filter(TRTEMFL == "Y" & OCMQCLSS == ocmqclass) %>% - select(USUBJID, TRTEMFL, OCMQSOC, OCMQNAM, AEDECOD) - -adae <- adae_full %>% - group_by(OCMQSOC) %>% - slice(1) %>% - ungroup() - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) -} - -# join data together -ae <- adae %>% right_join(., adsl, by = c("USUBJID")) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -ref_path <- c("colspan_trt", " ", "TRT01A", "Placebo") -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) -} - -lyt <- lyt %>% - split_rows_by( - "OCMQSOC", - split_label = "Organ System~[super a]", - split_fun = trim_levels_in_group("OCMQNAM"), - label_pos = "topleft", - section_div = c(" "), - nested = FALSE - ) %>% - summarize_row_groups( - "OCMQSOC", - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - split_rows_by( - "OCMQNAM", - split_label = paste0("OCMQ (", ocmqclass, ")"), - split_fun = trim_levels_in_group("AEDECOD"), - label_pos = "topleft", - nested = TRUE - ) %>% - summarize_row_groups( - "OCMQNAM", - cfun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = append(extra_args_rr, NULL) - ) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, ae, alt_counts_df = adsl) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - result <- sort_at_path( - result, - c("root", "OCMQSOC"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("root", "OCMQSOC", "*", "OCMQNAM"), - scorefun = jj_complex_scorefun() - ) - result <- sort_at_path( - result, - c("root", "OCMQSOC", "*", "OCMQNAM", "*", "AEDECOD"), - scorefun = jj_complex_scorefun() - ) -} - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 17, 17, 17, 17, 29, 29) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae18a.R b/tests/testthat/source_code/tsfae18a.R new file mode 100644 index 00000000..ffbfb9d1 --- /dev/null +++ b/tests/testthat/source_code/tsfae18a.R @@ -0,0 +1,192 @@ +library(envsetup) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFAE18a" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +popfl <- "SAFFL" +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +combined_colspan_trt <- TRUE +risk_diff <- TRUE + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + mutate( + colspan_trt = factor( + if_else(.data[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") + ) + ) |> + mutate(rrisk_header = "Risk Difference (%) (95% CI)") |> + mutate(rrisk_label = factor(paste(.data[[trtvar]], "vs", ctrl_grp))) |> + select(USUBJID, all_of(trtvar), colspan_trt, rrisk_header, rrisk_label) + +adagocmq <- adagocmq_jnj |> + filter(.data[[popfl]] == "Y", ACAT1 == "Rhabdomyolysis", ANL01FL == "Y") |> + select(USUBJID, ATERM, ATERMN) |> + right_join(adsl) |> + mutate( + criterion = factor(if_else( + ATERMN %in% 41:44, + "Subjects with >=1 algorithmic criterion", + " " + )) + ) |> + mutate( + ATERM = factor( + ATERM, + unique(c( + "Any muscle injury OCMQ narrow term", + "Urine myoglobin >ULN", + "CPK >5x ULN", + "Myalgia + weakness + chromaturia", + levels(ATERM) + )) + ) + ) + +################################################################################ +# Define layout and build table: +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +if (combined_colspan_trt) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # Choose if any facets need to be removed + # e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +label_map <- tibble( + value = levels(adagocmq[["ATERM"]])[1:4], + label = c( + "Any muscle injury OCMQ narrow term", + "Urine myoglobin >ULN", + "CPK >5x ULN~[super a]", + "Myalgia + weakness + chromaturia~[super b]" + ) +) + +lyt <- + basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" + ) |> + append_topleft(c("Algorithmic OCMQ", " ", " Criterion, n (%)")) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (risk_diff) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels(ctrl_grp) + ) +} + +lyt <- lyt |> + split_rows_by( + "criterion", + split_fun = keep_split_levels("Subjects with >=1 algorithmic criterion") + ) |> + summarize_row_groups( + "criterion", + cfun = a_freq_j, + extra_args = list( + method = "wald", + .stats = "count_unique_fraction", + ref_path = ref_path + ) + ) |> + analyze( + "ATERM", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + method = "wald", + .stats = "count_unique_fraction", + ref_path = ref_path, + val = levels(adagocmq[["ATERM"]])[1:4], + label_map = label_map + ) + ) + +result <- build_table(lyt, adagocmq, alt_counts_df = adsl, round_type = "sas") + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 5, 5, 5, 17, 29, 29) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae18b.R b/tests/testthat/source_code/tsfae18b.R new file mode 100644 index 00000000..783c68c3 --- /dev/null +++ b/tests/testthat/source_code/tsfae18b.R @@ -0,0 +1,238 @@ +library(envsetup) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFAE18b" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +popfl <- "SAFFL" +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +combined_colspan_trt <- TRUE +risk_diff <- TRUE + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + mutate( + colspan_trt = factor( + if_else(.data[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") + ) + ) |> + mutate(rrisk_header = "Risk Difference (%) (95% CI)") |> + mutate(rrisk_label = factor(paste(.data[[trtvar]], "vs", ctrl_grp))) |> + select( + USUBJID, + all_of(trtvar), + DIABETFL, + colspan_trt, + rrisk_header, + rrisk_label + ) + +adagocmq <- adagocmq_jnj |> + filter(.data[[popfl]] == "Y", ACAT1 == "Hypoglycemia", ANL01FL == "Y") |> + select(USUBJID, ATERMN, ATERM) |> + right_join(adsl) |> + mutate( + DIABETFL = if_else( + DIABETFL == "Y", + "History of diabetes", + "No history of diabetes" + ), + DIABETFL = factor( + DIABETFL, + levels = c( + "No history of diabetes", + "History of diabetes" + ) + ) + ) |> + mutate( + criterion = factor(if_else( + ATERMN %in% 31:34, + "Subjects with >=1 algorithmic criterion", + " " + )) + ) |> + mutate( + ATERM = factor( + ATERM, + unique(c( + "Any hypoglycemia OCMQ narrow term", + if_else( + any(grepl("mg/dL", ATERM)), + "Plasma glucose <54 mg/dL", + "Plasma glucose <3.0 mmol/L" + ), + if_else( + any(grepl("mg/dL", ATERM)), + "Hypoglycemia term + plasma glucose <70 mg/dL", + "Hypoglycemia term + plasma glucose <3.885 mmol/L" + ), + if_else( + any(grepl("mg/dL", ATERM)), + ">=2 hypoglycemia terms + >=2 episodes of plasma glucose <70 mg/dL", + ">=2 hypoglycemia terms + >=2 episodes of plasma glucose <3.885 mmol/L" + ), + levels(ATERM) + )) + ) + ) + +################################################################################ +# Define layout and build table: +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +if (combined_colspan_trt) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # Choose if any facets need to be removed + # e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +label_map <- tibble( + value = levels(adagocmq[["ATERM"]])[1:4], + label = value +) + +label_map[["label"]][3] <- paste0( + gsub("term", "term~[super a]", label_map[["label"]][3]), + "~[super b]" +) + +label_map[["label"]][4] <- + gsub("terms", "terms~[super a]", label_map[["label"]][4]) + +lyt <- + basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" + ) |> + append_topleft(c("Population", " ", " Algorithmic OCMQ Criterion, n (%)")) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (risk_diff) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels(ctrl_grp) + ) +} + +lyt <- lyt |> + split_rows_by( + "DIABETFL", + split_fun = add_overall_level("All subjects"), + section_div = " " + ) |> + summarize_row_groups( + "DIABETFL", + cfun = a_freq_j, + extra_args = list(riskdiff = FALSE, .stats = "count_unique_fraction") + ) |> + split_rows_by( + "criterion", + split_fun = keep_split_levels("Subjects with >=1 algorithmic criterion") + ) |> + summarize_row_groups( + "criterion", + cfun = a_freq_j, + extra_args = list( + method = "wald", + .stats = "count_unique_fraction", + ref_path = ref_path + ) + ) |> + analyze( + "ATERM", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + method = "wald", + .stats = "count_unique_fraction", + ref_path = ref_path, + val = levels(adagocmq[["ATERM"]])[1:4], + label_map = label_map + ) + ) + +result <- build_table(lyt, adagocmq, alt_counts_df = adsl, round_type = "sas") + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 23, 23, 25, 23, 26, 24) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae18c.R b/tests/testthat/source_code/tsfae18c.R new file mode 100644 index 00000000..cc18450b --- /dev/null +++ b/tests/testthat/source_code/tsfae18c.R @@ -0,0 +1,233 @@ +library(envsetup) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFAE18c" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +popfl <- "SAFFL" +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +combined_colspan_trt <- TRUE +risk_diff <- TRUE + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + mutate( + colspan_trt = factor( + if_else(.data[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") + ) + ) |> + mutate(rrisk_header = "Risk Difference (%) (95% CI)") |> + mutate(rrisk_label = factor(paste(.data[[trtvar]], "vs", ctrl_grp))) |> + select( + USUBJID, + all_of(trtvar), + DIABETFL, + colspan_trt, + rrisk_header, + rrisk_label + ) + +adagocmq <- adagocmq_jnj |> + filter(.data[[popfl]] == "Y", ACAT1 == "Hyperglycemia", ANL01FL == "Y") |> + select(USUBJID, ATERMN, ATERM) |> + right_join(adsl) |> + mutate( + DIABETFL = if_else( + DIABETFL == "Y", + "History of diabetes", + "No history of diabetes" + ), + DIABETFL = factor( + DIABETFL, + levels = c( + "No history of diabetes", + "History of diabetes" + ) + ) + ) |> + mutate( + criterion = factor(if_else( + ATERMN %in% 21:27, + "Subjects with >=1 algorithmic criterion", + " " + )) + ) |> + mutate( + ATERM = factor( + ATERM, + unique(c( + "Any hyperglycemia OCMQ narrow term", + if_else( + any(grepl("mg/dL", ATERM)), + "Fasting plasma glucose >=126 mg/dL", + "Fasting plasma glucose >=6.993 mmol/L" + ), + if_else( + any(grepl("mg/dL", ATERM)), + ">=2 plasma glucoses >180 mg/dL", + ">=2 plasma glucoses >9.99 mmol/L" + ), + "Any new diabetes concomitant medication", + "Postbaseline HbA1c >=6.5%", + "HbA1c increase >=0.3% with postbaseline HbA1c >=5.7%", + if_else( + any(grepl("mg/dL", ATERM)), + paste( + "Change from baseline fasting plasma glucose >=20 mg/dL", + "with postbaseline fasting plasma glucose >100 mg/dL" + ), + paste( + "Change from baseline fasting plasma glucose >=1.11 mmol/L", + "with postbaseline fasting plasma glucose >5.55 mmol/L" + ) + ), + levels(ATERM) + )) + ) + ) + +################################################################################ +# Define layout and build table: +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +if (combined_colspan_trt) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # Choose if any facets need to be removed + # e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +lyt <- + basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" + ) |> + append_topleft(c("Population", " ", " Algorithmic OCMQ Criterion, n (%)")) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (risk_diff) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels(ctrl_grp) + ) +} + +lyt <- lyt |> + split_rows_by( + "DIABETFL", + split_fun = add_overall_level("All subjects"), + section_div = " " + ) |> + summarize_row_groups( + "DIABETFL", + cfun = a_freq_j, + extra_args = list(riskdiff = FALSE, .stats = "count_unique_fraction") + ) |> + split_rows_by( + "criterion", + split_fun = keep_split_levels("Subjects with >=1 algorithmic criterion") + ) |> + summarize_row_groups( + "criterion", + cfun = a_freq_j, + extra_args = list( + method = "wald", + .stats = "count_unique_fraction", + ref_path = ref_path + ) + ) |> + analyze( + "ATERM", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + method = "wald", + .stats = "count_unique_fraction", + ref_path = ref_path, + val = levels(adagocmq[["ATERM"]])[1:7] + ) + ) + +result <- build_table(lyt, adagocmq, alt_counts_df = adsl, round_type = "sas") + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 23, 23, 25, 23, 35, 33) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae18d.R b/tests/testthat/source_code/tsfae18d.R new file mode 100644 index 00000000..8c3b26d4 --- /dev/null +++ b/tests/testthat/source_code/tsfae18d.R @@ -0,0 +1,184 @@ +library(envsetup) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFAE18d" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +popfl <- "SAFFL" +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +combined_colspan_trt <- TRUE +risk_diff <- TRUE + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + mutate( + colspan_trt = factor( + if_else(.data[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") + ) + ) |> + mutate(rrisk_header = "Risk Difference (%) (95% CI)") |> + mutate(rrisk_label = factor(paste(.data[[trtvar]], "vs", ctrl_grp))) |> + select(USUBJID, all_of(trtvar), colspan_trt, rrisk_header, rrisk_label) + +adagocmq <- adagocmq_jnj |> + filter(.data[[popfl]] == "Y", ACAT1 == "Hypersensitivity", ANL01FL == "Y") |> + select(USUBJID, ATERM, ATERMN) |> + right_join(adsl) |> + mutate( + criterion = factor(if_else( + ATERMN %in% 11:14, + "Subjects with >=1 algorithmic criterion", + " " + )) + ) |> + mutate( + ATERM = factor( + ATERM, + unique(c( + "Any hypersensitivity OCMQ narrow term", + "Respiratory + skin reaction", + "Respiratory + systemic reaction", + "Skin + systemic reaction", + levels(ATERM) + )) + ) + ) + +################################################################################ +# Define layout and build table: +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +if (combined_colspan_trt) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # Choose if any facets need to be removed + # e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +lyt <- + basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" + ) |> + append_topleft(c("Algorithmic OCMQ", " ", " Criterion, n (%)")) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (risk_diff) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels(ctrl_grp) + ) +} + +lyt <- lyt |> + split_rows_by( + "criterion", + split_fun = keep_split_levels( + "Subjects with >=1 algorithmic criterion" + ) + ) |> + summarize_row_groups( + "criterion", + cfun = a_freq_j, + extra_args = list( + method = "wald", + .stats = "count_unique_fraction", + ref_path = ref_path, + label = "Subjects with >=1 algorithmic criterion~[super a]" + ) + ) |> + analyze( + "ATERM", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + method = "wald", + .stats = "count_unique_fraction", + ref_path = ref_path, + val = levels(adagocmq[["ATERM"]])[1:4] + ) + ) + +result <- build_table(lyt, adagocmq, alt_counts_df = adsl, round_type = "sas") + +## Remove the N=xx column headers for the risk difference columns +result <- remove_col_count(result) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 17, 5, 17, 17, 29, 29) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae19a.R b/tests/testthat/source_code/tsfae19a.R deleted file mode 100644 index 927b4efb..00000000 --- a/tests/testthat/source_code/tsfae19a.R +++ /dev/null @@ -1,249 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae19a.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Adverse Events by -## Male-specific OCMQ (Narrow) and Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 2025-07-21 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE19a.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored two_tier_cpct_relrisk to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Define sex to filter on (default=M) -# - Define the OCMQ class to filter on (default=Narrow) -# - Define the OCMQ gender flag to filter on (default=GENSPMFL) -# - Define the list of OCMQNAMs that must appear in the table -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE19a" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" -sex <- "M" -ocmqclass <- "Narrow" -ocmqflag <- "GENSPMFL" -ocmqnam_list <- c("Erectile Dysfunction", "Gynecomastia") -combined_colspan_trt <- FALSE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & SEX == sex) %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adae <- adaeocmq_jnj %>% - filter( - TRTEMFL == "Y" & OCMQCLSS == ocmqclass & (!!rlang::sym(ocmqflag) == "Y") - ) %>% - select(USUBJID, TRTEMFL, OCMQNAM, AEDECOD, !!rlang::sym(ocmqflag)) %>% - mutate( - OCMQNAM = factor(OCMQNAM, levels = union(levels(OCMQNAM), ocmqnam_list)), - ) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - ### to avoid problems with level of trtvar not observed in main domain - adsl$rrisk_label <- factor( - paste(adsl[[trtvar]], paste("vs", ctrl_grp)), - levels = paste(levels(adsl[[trtvar]]), paste("vs", ctrl_grp)) - ) -} - -# join data together -adae <- adae %>% inner_join(., adsl, by = intersect(names(adae), names(adsl))) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -# new approach to prevent label problems when treatment group not available in domain dataset -ctrl_grp2 <- paste(ctrl_grp, "vs", ctrl_grp) -ref_path <- c("colspan_trt", " ", "rrisk_label", ctrl_grp2) -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - # split_cols_by(trtvar, labels_var = "rrisk_label", split_fun = remove_split_levels("Placebo")) - ### do not use labels_var, but rrisk_label as variable - ### note updated level in remove_split_levels - split_cols_by("rrisk_label", split_fun = remove_split_levels(ctrl_grp2)) -} - -lyt <- lyt %>% - split_rows_by( - "OCMQNAM", - split_label = paste0("OCMQ (", ocmqclass, ")"), - split_fun = keep_split_levels(ocmqnam_list), - label_pos = "topleft", - section_div = c(" "), - child_labels = "hidden", - nested = FALSE - ) %>% - summarize_row_groups( - "OCMQNAM", - cfun = a_freq_j, - extra_args = extra_args_rr - ) %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = c(extra_args_rr, list(drop_levels = TRUE)) - ) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, adae, alt_counts_df = adsl) - -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - # result <- sort_at_path(result, c("OCMQNAM"), scorefun = jj_complex_scorefun()) - result <- sort_at_path( - result, - c("OCMQNAM", "*", "AEDECOD"), - scorefun = jj_complex_scorefun() - ) -} - -## note : perform this step after sorting, otherwise can result in errors (unable to find children AEDECOD) -## extra step : to remove lines with No data to report: note usage of trim_rows rather than prune_table -## this to ensure the content rows with empty levels are kept - -prune_empty_level_tablerow <- function(tt) { - if (is(tt, "ContentRow")) { - return(FALSE) - } - if (is(tt, "TableRow")) { - return(all_zero_or_na(tt)) - } - kids <- tree_children(tt) - length(kids) == 0 -} - -result <- result %>% trim_rows(prune_empty_level_tablerow) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(50, 17, 5, 17, 31, 31) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae19b.R b/tests/testthat/source_code/tsfae19b.R deleted file mode 100644 index 2f91ce6e..00000000 --- a/tests/testthat/source_code/tsfae19b.R +++ /dev/null @@ -1,249 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae19b.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Adverse Events by -## Male-specific OCMQ (Broad) and Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 2025-07-21 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE19b.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored two_tier_cpct_relrisk to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Define sex to filter on (default=M) -# - Define the OCMQ class to filter on (default=Broad) -# - Define the OCMQ gender flag to filter on (default=GENSPMFL) -# - Define the list of OCMQNAMs that must appear in the table -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE19b" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" -sex <- "M" -ocmqclass <- "Broad" -ocmqflag <- "GENSPMFL" -ocmqnam_list <- c("Erectile Dysfunction", "Gynecomastia") -combined_colspan_trt <- FALSE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & SEX == sex) %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adae <- adaeocmq_jnj %>% - filter( - TRTEMFL == "Y" & OCMQCLSS == ocmqclass & (!!rlang::sym(ocmqflag) == "Y") - ) %>% - select(USUBJID, TRTEMFL, OCMQNAM, AEDECOD, !!rlang::sym(ocmqflag)) %>% - mutate( - OCMQNAM = factor(OCMQNAM, levels = union(levels(OCMQNAM), ocmqnam_list)), - ) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - ### to avoid problems with level of trtvar not observed in main domain - adsl$rrisk_label <- factor( - paste(adsl[[trtvar]], paste("vs", ctrl_grp)), - levels = paste(levels(adsl[[trtvar]]), paste("vs", ctrl_grp)) - ) -} - -# join data together -adae <- adae %>% inner_join(., adsl, by = intersect(names(adae), names(adsl))) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -# new approach to prevent label problems when treatment group not available in domain dataset -ctrl_grp2 <- paste(ctrl_grp, "vs", ctrl_grp) -ref_path <- c("colspan_trt", " ", "rrisk_label", ctrl_grp2) -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - # split_cols_by(trtvar, labels_var = "rrisk_label", split_fun = remove_split_levels("Placebo")) - ### do not use labels_var, but rrisk_label as variable - ### note updated level in remove_split_levels - split_cols_by("rrisk_label", split_fun = remove_split_levels(ctrl_grp2)) -} - -lyt <- lyt %>% - split_rows_by( - "OCMQNAM", - split_label = paste0("OCMQ (", ocmqclass, ")"), - split_fun = keep_split_levels(ocmqnam_list), - label_pos = "topleft", - section_div = c(" "), - child_labels = "hidden", - nested = FALSE - ) %>% - summarize_row_groups( - "OCMQNAM", - cfun = a_freq_j, - extra_args = extra_args_rr - ) %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = c(extra_args_rr, list(drop_levels = TRUE)) - ) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, adae, alt_counts_df = adsl) - -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - # result <- sort_at_path(result, c("OCMQNAM"), scorefun = jj_complex_scorefun()) - result <- sort_at_path( - result, - c("OCMQNAM", "*", "AEDECOD"), - scorefun = jj_complex_scorefun() - ) -} - -## note : perform this step after sorting, otherwise can result in errors (unable to find children AEDECOD) -## extra step : to remove lines with No data to report: note usage of trim_rows rather than prune_table -## this to ensure the content rows with empty levels are kept - -prune_empty_level_tablerow <- function(tt) { - if (is(tt, "ContentRow")) { - return(FALSE) - } - if (is(tt, "TableRow")) { - return(all_zero_or_na(tt)) - } - kids <- tree_children(tt) - length(kids) == 0 -} - -result <- result %>% trim_rows(prune_empty_level_tablerow) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 5, 5, 17, 31, 31) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae19c.R b/tests/testthat/source_code/tsfae19c.R deleted file mode 100644 index 174c52d4..00000000 --- a/tests/testthat/source_code/tsfae19c.R +++ /dev/null @@ -1,255 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae19c.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Adverse Events by -## Female-specific OCMQ (Narrow) and Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 2025-07-21 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE19c.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored two_tier_cpct_relrisk to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Define sex to filter on (default=F) -# - Define the OCMQ class to filter on (default=Narrow) -# - Define the OCMQ gender flag to filter on (default=GENSPFFL) -# - Define the list of OCMQNAMs that must appear in the table -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE19c" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" -sex <- "F" -ocmqclass <- "Narrow" -ocmqflag <- "GENSPFFL" -ocmqnam_list <- c( - "Abnormal Uterine Bleeding", - "Amenorrhea", - "Bacterial Vaginosis", - "Decreased Menstrual Bleeding", - "Excessive Menstrual Bleeding" -) -combined_colspan_trt <- FALSE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & SEX == sex) %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adae <- adaeocmq_jnj %>% - filter( - TRTEMFL == "Y" & OCMQCLSS == ocmqclass & (!!rlang::sym(ocmqflag) == "Y") - ) %>% - select(USUBJID, TRTEMFL, OCMQNAM, AEDECOD, !!rlang::sym(ocmqflag)) %>% - mutate( - OCMQNAM = factor(OCMQNAM, levels = union(levels(OCMQNAM), ocmqnam_list)), - ) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - ### to avoid problems with level of trtvar not observed in main domain - adsl$rrisk_label <- factor( - paste(adsl[[trtvar]], paste("vs", ctrl_grp)), - levels = paste(levels(adsl[[trtvar]]), paste("vs", ctrl_grp)) - ) -} - -# join data together -adae <- adae %>% inner_join(., adsl, by = intersect(names(adae), names(adsl))) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -# new approach to prevent label problems when treatment group not available in domain dataset -ctrl_grp2 <- paste(ctrl_grp, "vs", ctrl_grp) -ref_path <- c("colspan_trt", " ", "rrisk_label", ctrl_grp2) -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - # split_cols_by(trtvar, labels_var = "rrisk_label", split_fun = remove_split_levels("Placebo")) - ### do not use labels_var, but rrisk_label as variable - ### note updated level in remove_split_levels - split_cols_by("rrisk_label", split_fun = remove_split_levels(ctrl_grp2)) -} - -lyt <- lyt %>% - split_rows_by( - "OCMQNAM", - split_label = paste0("OCMQ (", ocmqclass, ")"), - split_fun = keep_split_levels(ocmqnam_list), - label_pos = "topleft", - section_div = c(" "), - child_labels = "hidden", - nested = FALSE - ) %>% - summarize_row_groups( - "OCMQNAM", - cfun = a_freq_j, - extra_args = extra_args_rr - ) %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = c(extra_args_rr, list(drop_levels = TRUE)) - ) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, adae, alt_counts_df = adsl) - -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - # result <- sort_at_path(result, c("OCMQNAM"), scorefun = jj_complex_scorefun()) - result <- sort_at_path( - result, - c("OCMQNAM", "*", "AEDECOD"), - scorefun = jj_complex_scorefun() - ) -} - -## note : perform this step after sorting, otherwise can result in errors (unable to find children AEDECOD) -## extra step : to remove lines with No data to report: note usage of trim_rows rather than prune_table -## this to ensure the content rows with empty levels are kept - -prune_empty_level_tablerow <- function(tt) { - if (is(tt, "ContentRow")) { - return(FALSE) - } - if (is(tt, "TableRow")) { - return(all_zero_or_na(tt)) - } - kids <- tree_children(tt) - length(kids) == 0 -} - -result <- result %>% trim_rows(prune_empty_level_tablerow) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 17, 5, 5, 28, 24) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae19d.R b/tests/testthat/source_code/tsfae19d.R deleted file mode 100644 index 88b62c17..00000000 --- a/tests/testthat/source_code/tsfae19d.R +++ /dev/null @@ -1,255 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae19d.R -## R version: 4.4.1 -## junco Version: 1.0 -## Short Description: Subjects With Treatment-emergent Adverse Events by -## Female-specific OCMQ (Broad) and Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 28 Apr 2025 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE19d.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: Code Refactoring -## Date: 2025-08-13 -## Description: Refactored two_tier_cpct_relrisk to a_freq_j -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Define sex to filter on (default=F) -# - Define the OCMQ class to filter on (default=Broad) -# - Define the OCMQ gender flag to filter on (default=GENSPFFL) -# - Define the list of OCMQNAMs that must appear in the table -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Choose whether or not you want to present the risk difference columns (default=TRUE) -# - Choose which risk difference method you would like (default=Wald) -# - Define what the control treatment group is for your study (e.g Placebo) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSFAE19d" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" -sex <- "F" -ocmqclass <- "Broad" -ocmqflag <- "GENSPFFL" -ocmqnam_list <- c( - "Abnormal Uterine Bleeding", - "Amenorrhea", - "Bacterial Vaginosis", - "Decreased Menstrual Bleeding", - "Excessive Menstrual Bleeding" -) -combined_colspan_trt <- FALSE -risk_diff <- TRUE -rr_method <- "wald" -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & SEX == sex) %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adae <- adaeocmq_jnj %>% - filter( - TRTEMFL == "Y" & OCMQCLSS == ocmqclass & (!!rlang::sym(ocmqflag) == "Y") - ) %>% - select(USUBJID, TRTEMFL, OCMQNAM, AEDECOD, !!rlang::sym(ocmqflag)) %>% - mutate( - OCMQNAM = factor(OCMQNAM, levels = union(levels(OCMQNAM), ocmqnam_list)), - ) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - ### to avoid problems with level of trtvar not observed in main domain - adsl$rrisk_label <- factor( - paste(adsl[[trtvar]], paste("vs", ctrl_grp)), - levels = paste(levels(adsl[[trtvar]]), paste("vs", ctrl_grp)) - ) -} - -# join data together -adae <- adae %>% inner_join(., adsl, by = intersect(names(adae), names(adsl))) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ - -# new approach to prevent label problems when treatment group not available in domain dataset -ctrl_grp2 <- paste(ctrl_grp, "vs", ctrl_grp) -ref_path <- c("colspan_trt", " ", "rrisk_label", ctrl_grp2) -extra_args_rr <- list( - method = rr_method, - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - # split_cols_by(trtvar, labels_var = "rrisk_label", split_fun = remove_split_levels("Placebo")) - ### do not use labels_var, but rrisk_label as variable - ### note updated level in remove_split_levels - split_cols_by("rrisk_label", split_fun = remove_split_levels(ctrl_grp2)) -} - -lyt <- lyt %>% - split_rows_by( - "OCMQNAM", - split_label = paste0("OCMQ (", ocmqclass, ")"), - split_fun = keep_split_levels(ocmqnam_list), - label_pos = "topleft", - section_div = c(" "), - child_labels = "hidden", - nested = FALSE - ) %>% - summarize_row_groups( - "OCMQNAM", - cfun = a_freq_j, - extra_args = extra_args_rr - ) %>% - analyze( - "AEDECOD", - afun = a_freq_j, - extra_args = c(extra_args_rr, list(drop_levels = TRUE)) - ) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, adae, alt_counts_df = adsl) - -# If there is no data display "No data to display" text -if (nrow(adae) == 0) { - result <- safe_prune_table(result) -} - -######################################################################################### -# Post-Processing step to sort by descending count on chosen active treatment columns. -# Default is the last treatment (inc. Combined if applicable) under the active treatment -# spanning header (defaulted to colspan_trt variable). See function documentation for -# jj_complex_scorefun should your require a different sorting behavior. -######################################################################################### - -if (nrow(adae) != 0) { - # result <- sort_at_path(result, c("OCMQNAM"), scorefun = jj_complex_scorefun()) - result <- sort_at_path( - result, - c("OCMQNAM", "*", "AEDECOD"), - scorefun = jj_complex_scorefun() - ) -} - -## note : perform this step after sorting, otherwise can result in errors (unable to find children AEDECOD) -## extra step : to remove lines with No data to report: note usage of trim_rows rather than prune_table -## this to ensure the content rows with empty levels are kept - -prune_empty_level_tablerow <- function(tt) { - if (is(tt, "ContentRow")) { - return(FALSE) - } - if (is(tt, "TableRow")) { - return(all_zero_or_na(tt)) - } - kids <- tree_children(tt) - length(kids) == 0 -} - -result <- result %>% trim_rows(prune_empty_level_tablerow) - -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(53, 5, 17, 17, 29, 29) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae20a.R b/tests/testthat/source_code/tsfae20a.R index 60006417..721bbbe1 100644 --- a/tests/testthat/source_code/tsfae20a.R +++ b/tests/testthat/source_code/tsfae20a.R @@ -1,31 +1,5 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae20a.R -## R version: 4.2.1 -## Short Description: Program to create tsfae20a: Summary of Demographic -## Characteristics for Subjects With Treatment-emergent -## Adverse Events -## Author: Johnson & Johnson Innovative Medicine -## Date: 07 Dec 2023 -## Input: adsl.rds, adae.rds -## Output: tsfae20a.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) -library(forcats) library(dplyr) library(rtables) library(junco) @@ -35,194 +9,165 @@ library(junco) ################################################################################ tblid <- "TSFAE20a" -titles <- list( +fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +trtvar <- "TRT01A" +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) -fileid <- write_path(opath, tblid) -popfl <- "SAFFL" -trtvar <- "TRT01A" -subjFilterText <- "AE" -ctrl_grp <- "Placebo" ################################################################################ -# Process Data -# - Sub-setting performed on a subject-level; certain tables may require a more -# granular, column-based sub-setting. -# - Factor for Active Treatment spanning header added below. -# - Additional factor reformatting added below. +# Process data: +# Create variables for column spanning headers: +# - colspan_trt: Used to generate the "Active Study Agent" spanning header. +# - COLSPAN_REL: Set to "AEs" for all subjects. Used along with the add_combo_levels() +# split function to generate separate facets for AEs & Related AEs. ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + filter(!!rlang::sym(popfl) == "Y") |> create_colspan_var( - non_active_grp = ctrl_grp, + non_active_grp = "Placebo", non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% + ) |> + mutate(COLSPAN_REL = "AEs") |> select( USUBJID, !!rlang::sym(popfl), !!rlang::sym(trtvar), - SEX_DECODE, - AGEGR1, - RACE_DECODE, - ETHNIC_DECODE, - colspan_trt + colspan_trt, + COLSPAN_REL ) -# Factor reformatting (e.g., Include missing in the "Unknown" category). -adsl$SEX_DECODE <- forcats::fct_na_value_to_level( - adsl$SEX_DECODE, - level = "Unknown" -) - -adsl$AGEGR1_DECODE <- forcats::fct_na_value_to_level( - factor(stringr::str_replace(as.character(adsl$AGEGR1), ">=", "\u2265")), - level = "Unknown" -) +adae <- adae_jnj |> + filter(TRTEMFL == "Y") |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AEREL) -adsl$RACE_DECODE <- forcats::fct_collapse( - forcats::fct_na_value_to_level(adsl$RACE_DECODE, level = "Unknown"), - "Not reported or unknown" = c("Not reported", "Unknown") -) - -adsl$ETHNIC_DECODE <- forcats::fct_collapse( - forcats::fct_na_value_to_level(adsl$ETHNIC_DECODE, level = "Unknown"), - "Not reported or unknown" = c("Not reported", "Unknown") -) -had_ae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% - select(USUBJID, TRTEMFL) %>% - distinct(USUBJID, .keep_all = TRUE) +adae <- inner_join(adae, adsl, by = c("USUBJID")) -adsl <- adsl %>% - left_join(had_ae) %>% - mutate(TRTEMFL = ifelse(is.na(TRTEMFL), "N", "Y")) ################################################################################ -# Define layout and build table +# Define layout and build table: ################################################################################ colspan_trt_map <- create_colspan_map( adsl, - non_active_grp = ctrl_grp, + non_active_grp = "Placebo", non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar ) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - -add_active_combo <- make_split_fun( - post = list( - add_combo_facet( - name = "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ), - cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - ) -) -extra_args_rr <- list( - riskdiff = FALSE +combodf <- tribble( + ~valname, + ~label, + ~levelcombo, + ~exargs, + "RELATED", + "Related AEs", + c("AEs"), + list() ) -extra_args_rr2 <- append( - extra_args_rr, - list(resp_var = "TRTEMFL", drop_levels = TRUE) +extra_args1 <- list( + .stats = c("count_unique_fraction"), + subcol_split = "RELATED", + subcol_var = "AEREL", + subcol_val = "RELATED" ) + lyt <- basic_table( - show_colcounts = TRUE, colcount_format = "N=xx", top_level_section_div = " " -) %>% - append_topleft("Characteristic") %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar, split_fun = add_active_combo) - -lyt <- lyt %>% + ) |> + split_cols_by(trtvar, show_colcounts = TRUE) |> + split_cols_by("COLSPAN_REL", split_fun = add_combo_levels(combodf, trim = TRUE), show_colcounts = FALSE) |> analyze( "TRTEMFL", - afun = a_freq_j, + afun = a_freq_subcol_j, extra_args = append( - extra_args_rr, + extra_args1, list( - label = paste("Subjects with >= 1", subjFilterText), - val = "Y", - .stats = c("count_unique_fraction") + label = "Subjects with >= 1 AE", + val = "Y" ) - ), - show_labels = "hidden" - ) %>% - analyze( - vars = "SEX_DECODE", - var_labels = "Sex, n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, - nested = FALSE - ) %>% - analyze( - vars = "AGEGR1_DECODE", - var_labels = "Age group (years), n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, - nested = FALSE - ) %>% - analyze( - vars = "RACE_DECODE", - var_labels = "Race, n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, - nested = FALSE - ) %>% - analyze( - vars = "ETHNIC_DECODE", - var_labels = "Ethnicity, n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, + ) + ) |> + split_rows_by( + "AEBODSYS", + split_label = "System Organ Class", + label_pos = "topleft", + split_fun = trim_levels_in_group("AEDECOD"), + section_div = " ", nested = FALSE - ) + ) |> + summarize_row_groups( + "AEBODSYS", + cfun = a_freq_subcol_j, + extra_args = extra_args1 + ) |> + analyze("AEDECOD", afun = a_freq_subcol_j, extra_args = extra_args1) |> + append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, adsl) +result <- build_table(lyt, adae, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: -# Prune any categories with all zeros: -################################################################################ - -result <- safe_prune_table(result, prune_func = count_pruner()) +# Sort by descending AEBODSYS/AEDECOD in combined AE column +################################################################################ + +result <- result |> + sort_at_path( + path = c("AEBODSYS"), + scorefun = cont_n_onecol("Active Study Agent.Xanomeline High Dose.AEs") + ) |> + sort_at_path( + path = c("AEBODSYS", "*", "AEDECOD"), + scorefun = score_occurrences_cols( + "Active Study Agent.Xanomeline High Dose.AEs" + ) + ) ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ -# Convert to tbl file and output table +# Convert to tbl file and output table: ################################################################################ -colwidth <- c(64, 29, 27, 29, 27) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(64, 21, 21, 21, 21, 21, 21) + +tt_to_tlgrtf( + result, + file = fileid, + orientation = "landscape", + nosplitin = list(cols = c(trtvar)) +) diff --git a/tests/testthat/source_code/tsfae20b.R b/tests/testthat/source_code/tsfae20b.R index e9f6c072..ab35f53e 100644 --- a/tests/testthat/source_code/tsfae20b.R +++ b/tests/testthat/source_code/tsfae20b.R @@ -1,31 +1,5 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae20b.R -## R version: 4.2.1 -## Short Description: Program to create tsfae20b: Summary of Demographic -## Characteristics for Subjects With Serious -## Treatment-emergent Adverse Events -## Author: Johnson & Johnson Innovative Medicine -## Date: 17 Nov 2023 -## Input: adsl.rds, adae.rds -## Output: tsfae20b.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) -library(forcats) library(dplyr) library(rtables) library(junco) @@ -35,89 +9,81 @@ library(junco) ################################################################################ tblid <- "TSFAE20b" -titles <- list( +fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +trtvar <- "TRT01A" +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) -fileid <- write_path(opath, tblid) -popfl <- "SAFFL" -trtvar <- "TRT01A" -subjFilterText <- "SAE" -ctrl_grp <- "Placebo" + ################################################################################ -# Process Data -# - Sub-setting performed on a subject-level; certain tables may require a more -# granular, column-based sub-setting. -# - Factor for Active Treatment spanning header added below. -# - Additional factor reformatting added below. +# Process data: +# Create variables for column spanning headers: +# - colspan_trt: Used to generate the "Active Study Agent" spanning header. +# - COLSPAN_TOX: Set to "AEs" for all subjects. Used along with the add_combo_levels() +# split function to generate separate facets for AEs & AEs with TOXGR > 3. ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + filter(!!rlang::sym(popfl) == "Y") |> create_colspan_var( - non_active_grp = ctrl_grp, + non_active_grp = "Placebo", non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% + ) |> + mutate(COLSPAN_TOX = "AEs") |> select( USUBJID, !!rlang::sym(popfl), !!rlang::sym(trtvar), - SEX_DECODE, - AGEGR1, - RACE_DECODE, - ETHNIC_DECODE, - colspan_trt + colspan_trt, + COLSPAN_TOX ) -# Factor reformatting (e.g., Include missing in the "Unknown" category). -adsl$SEX_DECODE <- forcats::fct_na_value_to_level( - adsl$SEX_DECODE, - level = "Unknown" -) - -adsl$AGEGR1_DECODE <- forcats::fct_na_value_to_level( - factor(stringr::str_replace(as.character(adsl$AGEGR1), ">=", "\u2265")), - level = "Unknown" -) - -adsl$RACE_DECODE <- forcats::fct_collapse( - forcats::fct_na_value_to_level(adsl$RACE_DECODE, level = "Unknown"), - "Not reported or unknown" = c("Not reported", "Unknown") -) - -adsl$ETHNIC_DECODE <- forcats::fct_collapse( - forcats::fct_na_value_to_level(adsl$ETHNIC_DECODE, level = "Unknown"), - "Not reported or unknown" = c("Not reported", "Unknown") -) - -had_ae <- adae_jnj %>% - filter(TRTEMFL == "Y" & AESER == "Y") %>% - select(USUBJID, TRTEMFL) %>% - distinct(USUBJID, .keep_all = TRUE) - -adsl <- adsl %>% - left_join(had_ae) %>% - mutate(TRTEMFL = ifelse(is.na(TRTEMFL), "N", "Y")) +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> + mutate(TOXGE3 = ifelse(AETOXGRN == 3 | AETOXGRN > 3, ">= 3", "< 3")) |> + select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AETOXGR, TOXGE3) +adae <- inner_join(adae, adsl, by = c("USUBJID")) ################################################################################ -# Define layout and build table +# Define layout and build table: ################################################################################ colspan_trt_map <- create_colspan_map( adsl, - non_active_grp = ctrl_grp, + non_active_grp = "Placebo", non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar ) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) add_active_combo <- make_split_fun( post = list( @@ -135,93 +101,108 @@ add_active_combo <- make_split_fun( ) ) -extra_args_rr <- list( - riskdiff = FALSE +# Create "TOX > 3" facet. +add_tox_levels <- make_split_fun( + post = list(add_combo_facet( + name = "TOXGR", + label = ">= Grade 3 AEs", + levels = c("AEs") + )) ) -extra_args_rr2 <- append( - extra_args_rr, - list(resp_var = "TRTEMFL", drop_levels = TRUE) +extra_args1 <- list( + .stats = c("count_unique_fraction"), + subcol_split = "TOXGR", + subcol_var = "TOXGE3", + subcol_val = ">= 3" ) -lyt <- basic_table( - show_colcounts = TRUE, - colcount_format = "N=xx", - top_level_section_div = " " -) %>% - append_topleft("Characteristic") %>% +lyt <- basic_table(top_level_section_div = " ") |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar, split_fun = add_active_combo) - -lyt <- lyt %>% + ) |> + split_cols_by( + trtvar, + split_fun = add_active_combo, + show_colcounts = TRUE, + colcount_format = "N=xx" + ) |> + split_cols_by("COLSPAN_TOX", split_fun = add_tox_levels) |> analyze( "TRTEMFL", - afun = a_freq_j, + nested = FALSE, + afun = a_freq_subcol_j, extra_args = append( - extra_args_rr, + extra_args1, list( - label = paste("Subjects with >= 1", subjFilterText), - val = "Y", - .stats = c("count_unique_fraction") + label = "Subjects with >= 1 AE", + val = "Y" ) - ), - show_labels = "hidden" - ) %>% - analyze( - vars = "SEX_DECODE", - var_labels = "Sex, n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, - nested = FALSE - ) %>% - analyze( - vars = "AGEGR1_DECODE", - var_labels = "Age group (years), n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, - nested = FALSE - ) %>% - analyze( - vars = "RACE_DECODE", - var_labels = "Race, n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, - nested = FALSE - ) %>% - analyze( - vars = "ETHNIC_DECODE", - var_labels = "Ethnicity, n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, + ) + ) |> + split_rows_by( + "AEBODSYS", + split_label = "System Organ Class", + label_pos = "topleft", + split_fun = trim_levels_in_group("AEDECOD"), + section_div = " ", nested = FALSE - ) + ) |> + summarize_row_groups( + "AEBODSYS", + cfun = a_freq_subcol_j, + extra_args = extra_args1 + ) |> + analyze("AEDECOD", afun = a_freq_subcol_j, extra_args = extra_args1) |> + append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, adsl) +result <- build_table(lyt, adae, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: -# Prune any categories with all zeros: -################################################################################ +# Sort by descending AEBODSYS/AEDECOD in combined TOXGR AE column +# Prune table to only keep those that meet x% criteria +################################################################################ + +result <- result |> + sort_at_path( + path = c("AEBODSYS"), + scorefun = cont_n_onecol("Active Study Agent.Combined.TOXGR") + ) |> + sort_at_path( + path = c("AEBODSYS", "*", "AEDECOD"), + scorefun = score_occurrences_cols("Active Study Agent.Combined.TOXGR") + ) -result <- safe_prune_table(result, prune_func = count_pruner()) +row_condition <- has_fraction_in_any_col( + atleast = .02, + col_names = c( + "Active Study Agent.Xanomeline High Dose.TOXGR", + "Active Study Agent.Xanomeline Low Dose.TOXGR", + "Active Study Agent.Combined.TOXGR", + " .Placebo.TOXGR" + ) +) + +result <- safe_prune_table(result, keep_rows(row_condition)) ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ -# Convert to tbl file and output table +# Convert to tbl file and output table: ################################################################################ -colwidth <- c(64, 27, 27, 27, 27) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(64, 21, 21, 21, 21, 21, 21, 21, 21) + +tt_to_tlgrtf( + result, + file = fileid, + orientation = "landscape", + nosplitin = list(cols = c(trtvar)) +) diff --git a/tests/testthat/source_code/tsfae20c.R b/tests/testthat/source_code/tsfae20c.R index df68aeb7..efb86ab1 100644 --- a/tests/testthat/source_code/tsfae20c.R +++ b/tests/testthat/source_code/tsfae20c.R @@ -1,28 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae20c.R -## R version: 4.4.1 -## Short Description: Demographic Characteristics for Subjects With -## Treatment-emergent Adverse Events - [OCMQ of Interest / -## Preferred Term of Interest] -## Author: Johnson & Johnson Innovative Medicine -## Date: 21 Jul 2025 -## Input: ADSL, ADAEOCMQ -## Output: TSFAE20c.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(forcats) @@ -35,193 +10,307 @@ library(junco) ################################################################################ tblid <- "TSFAE20c" -titles <- list( +fileid <- write_path(opath, tblid) +popfl <- "SAFFL" +trtvar <- "TRT01A" +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) -fileid <- write_path(opath, tblid) -popfl <- "SAFFL" -trtvar <- "TRT01A" -subjFilterText <- "Abdominal Pain" -varname <- "OCMQNAM" -ctrl_grp <- "Placebo" + ################################################################################ -# Process Data -# - Sub-setting performed on a subject-level; certain tables may require a more -# granular, column-based sub-setting. -# - Factor for Active Treatment spanning header added below. -# - Additional factor reformatting added below. +# Process data: +# Create variables for column spanning headers: +# - colspan_trt: Used to generate the "Active Study Agent" spanning header. +# - ACAT1: Month category for treatment discontinuation/completion. +# Filter AE dataframe to include 1st occurence of a given PT. ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> create_colspan_var( non_active_grp = "Placebo", non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% + ) |> + mutate( + months = (TRTEDY + 30) / 30.4375, + ACAT1 = case_when( + months <= 3 ~ "Within 3 months", + months > 3 & months <= 6 ~ "4 to 6 months", + months > 6 & months <= 9 ~ "7 to 9 months", + months > 9 & months <= 12 ~ "10 to 12 months", + months > 12 ~ "Beyond 13 months", + .default = NA_character_ + ), + ACAT1 = factor( + ACAT1, + levels = c( + "Within 3 months", + "4 to 6 months", + "7 to 9 months", + "10 to 12 months", + "Beyond 13 months" + ) + ) + ) |> select( USUBJID, !!rlang::sym(popfl), !!rlang::sym(trtvar), - SEX_DECODE, - AGEGR1, - RACE_DECODE, - ETHNIC_DECODE, - colspan_trt + colspan_trt, + TRTEDY, + ACAT1 ) -# Factor reformatting (e.g., Include missing in the "Unknown" category). -adsl$SEX_DECODE <- forcats::fct_na_value_to_level( - adsl$SEX_DECODE, - level = "Unknown" -) - -adsl$AGEGR1_DECODE <- forcats::fct_na_value_to_level( - factor(stringr::str_replace(as.character(adsl$AGEGR1), ">=", "\u2265")), - level = "Unknown" -) - -adsl$RACE_DECODE <- forcats::fct_collapse( - forcats::fct_na_value_to_level(adsl$RACE_DECODE, level = "Unknown"), - "Not reported or unknown" = c("Not reported", "Unknown") -) +adae <- adae_jnj |> + filter(TRTEMFL == "Y") |> + select( + USUBJID, + TRTEMFL, + AEBODSYS, + AEDECOD, + AETERM, + ASTDT, + ACAT1, + AOCCFL, + AOCCPFL, + AOCCSFL + ) |> + mutate( + ACAT1 = forcats::fct_na_value_to_level(factor( + ACAT1, + levels = c( + "Within 3 months", + "4 to 6 months", + "7 to 9 months", + "10 to 12 months", + "Beyond 13 months" + ) + )) + ) |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + arrange(USUBJID, AEBODSYS, AEDECOD, ASTDT) -adsl$ETHNIC_DECODE <- forcats::fct_collapse( - forcats::fct_na_value_to_level(adsl$ETHNIC_DECODE, level = "Unknown"), - "Not reported or unknown" = c("Not reported", "Unknown") -) +adae <- inner_join(adae, adsl |> select(-ACAT1), by = c("USUBJID")) -had_ae <- adaeocmq_jnj %>% - filter(TRTEMFL == "Y" & CQ01NAM == "Seizure") %>% - select(USUBJID, TRTEMFL) %>% - distinct(USUBJID, .keep_all = TRUE) +adae$TRTEMFL <- factor(adae$TRTEMFL) -adsl <- adsl %>% - left_join(had_ae) %>% - mutate(TRTEMFL = ifelse(is.na(TRTEMFL), "N", "Y")) ################################################################################ -# Define layout and build table +# Define layout and build table: ################################################################################ colspan_trt_map <- create_colspan_map( adsl, - non_active_grp = ctrl_grp, + non_active_grp = "Placebo", non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar ) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - -add_active_combo <- make_split_fun( - post = list( - add_combo_facet( - name = "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ), - cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - ) -) -extra_args_rr <- list( - riskdiff = FALSE +# This df generates facets with cumulative counts for .N_col. Note: These extra +# records must then be removed from the numerator by a cpct_filter_combos function. +combodf <- tribble( + ~valname, + ~label, + ~levelcombo, + ~exargs, + "Total", + "Total", + c("Within 3 months", "4 to 6 months", "7 to 9 months", "10 to 12 months", "Beyond 13 months", "(Missing)"), + list(), + "Thru 3 months", + "Within 3 months", + c("Within 3 months", "4 to 6 months", "7 to 9 months", "10 to 12 months", "Beyond 13 months"), + list(), + "Thru 6 months", + "4 to 6 months", + c("4 to 6 months", "7 to 9 months", "10 to 12 months", "Beyond 13 months"), + list(), + "Thru 9 months", + "7 to 9 months", + c("7 to 9 months", "10 to 12 months", "Beyond 13 months"), + list(), + "Thru 12 months", + "10 to 12 months", + c("10 to 12 months", "Beyond 13 months"), + list(), + "Over 13 months", + "Beyond 13 months", + c("Beyond 13 months"), + list() ) -extra_args_rr2 <- append( - extra_args_rr, - list(resp_var = "TRTEMFL", drop_levels = TRUE) + +extra_args1 <- list( + combosdf = combodf, + filter_var = "ACAT1", + do_not_filter = "Total", + .stats = "count_unique_fraction" ) -lyt <- basic_table( - show_colcounts = TRUE, - colcount_format = "N=xx", - top_level_section_div = " " -) %>% - append_topleft("Characteristic") %>% +lyt <- basic_table(top_level_section_div = " ") |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar, split_fun = add_active_combo) - -lyt <- lyt %>% + ) |> + split_cols_by(trtvar) |> + split_cols_by( + "ACAT1", + split_fun = add_combo_levels( + combosdf = combodf, + trim = FALSE, + keep_levels = combodf$valname + ) + ) |> analyze( - "TRTEMFL", + popfl, + show_labels = "hidden", afun = a_freq_j, + extra_args = list( + label = "Analysis set: Safety", + .stats = "n_altdf" + ) + ) |> + analyze( + "TRTEMFL", + nested = FALSE, + show_labels = "hidden", + afun = a_freq_combos_j, extra_args = append( - extra_args_rr, + extra_args1, list( - label = paste("Subjects with >= 1", subjFilterText), val = "Y", - .stats = c("count_unique_fraction") + label = "Subjects with >= 1 AE", + flag_var = "AOCCFL" ) - ), - show_labels = "hidden" - ) %>% - analyze( - vars = "SEX_DECODE", - var_labels = "Sex, n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, - nested = FALSE - ) %>% - analyze( - vars = "AGEGR1_DECODE", - var_labels = "Age group (years), n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, - nested = FALSE - ) %>% - analyze( - vars = "RACE_DECODE", - var_labels = "Race, n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, - nested = FALSE - ) %>% + ) + ) |> + split_rows_by( + "AEBODSYS", + split_label = "System Organ Class", + label_pos = "topleft", + split_fun = trim_levels_in_group("AEDECOD"), + section_div = c(" ") + ) |> + summarize_row_groups( + "AEBODSYS", + cfun = a_freq_combos_j, + extra_args = append( + extra_args1, + list(flag_var = "AOCCSFL") + ) + ) |> analyze( - vars = "ETHNIC_DECODE", - var_labels = "Ethnicity, n/Ns (%)", - show_labels = "visible", - afun = a_freq_resp_var_j, - extra_args = extra_args_rr2, - nested = FALSE + "AEDECOD", + afun = a_freq_combos_j, + extra_args = append( + extra_args1, + list(flag_var = "AOCCPFL") + ) + ) |> + append_topleft(" Preferred Term, n (%)") + +result <- build_table(lyt, adae, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Prune & sort results +################################################################################ + +result <- safe_prune_table(result, prune_func = bspt_pruner()) + +result <- result |> + sort_at_path( + path = c("root", "AEBODSYS"), + # Provide the entire path below in colpath argument. The paths can be identified using col_paths(result). + scorefun = jj_complex_scorefun( + colpath = c("colspan_trt", "Active Study Agent", "TRT01A", "Xanomeline High Dose", "ACAT1", "Total") + ) + ) |> + sort_at_path( + path = c("root", "AEBODSYS", "*", "AEDECOD"), + # Provide the entire path below in colpath argument. The paths can be identified using col_paths(result). + scorefun = jj_complex_scorefun( + colpath = c("colspan_trt", "Active Study Agent", "TRT01A", "Xanomeline High Dose", "ACAT1", "Total") + ) ) -result <- build_table(lyt, adsl) ################################################################################ -# Post-Processing: -# Prune any categories with all zeros: +# Post-Processing ################################################################################ -result <- safe_prune_table(result, prune_func = count_pruner()) +# to remove undesired % +force_format_on_tree <- function(tt, target_cols) { + if (methods::.hasSlot(tt, "content")) { + tt@content <- force_format_on_tree(tt@content, target_cols) + } + + if (methods::.hasSlot(tt, "children")) { + tt@children <- lapply(tt@children, force_format_on_tree, target_cols = target_cols) + } + + if (inherits(tt, "TableRow") && methods::.hasSlot(tt, "leaf_value")) { + for (i in seq_along(tt@leaf_value)) { + if (i %in% target_cols) { + raw_flattened <- unlist(tt@leaf_value[[i]]) + count_only <- as.numeric(raw_flattened[1]) + tt@leaf_value[[i]] <- rtables::rcell(count_only, format = "xx") + } + } + } + + return(tt) +} + +# Find the columns that isn't "Total" +col_names <- rtables::make_col_df(result)$name +cols_to_strip <- which(col_names != "Total") + +result <- force_format_on_tree(result, cols_to_strip) + ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ -# Convert to tbl file and output table +# Convert to tbl file and output table: ################################################################################ -colwidth <- c(64, 27, 27, 27, 27) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(64, 21, 7, 7, 7, 7, 7, 21, 7, 7, 7, 7, 7, 21, 7, 7, 7, 7, 7) + +tt_to_tlgrtf( + result, + file = fileid, + orientation = "landscape", + nosplitin = list(cols = c(trtvar)) +) diff --git a/tests/testthat/source_code/tsfae24f.R b/tests/testthat/source_code/tsfae20d.R similarity index 68% rename from tests/testthat/source_code/tsfae24f.R rename to tests/testthat/source_code/tsfae20d.R index 37b782cc..5e6de678 100644 --- a/tests/testthat/source_code/tsfae24f.R +++ b/tests/testthat/source_code/tsfae20d.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae24f.R -## R version: 4.2.1 -## Short Description: Program to create tsfae24f: Subjects with Treatment-emergent -## Adverse Events by SOC/PT and Onset Time -## Author: Johnson & Johnson Innovative Medicine -## Date: 26JAN2024 -## Input: adsl.RDS, adae.RDS -## Output: tsfae24f.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(tern) library(forcats) @@ -33,7 +9,7 @@ library(junco) # Define script level parameters: ################################################################################ -tblid <- "TSFAE24f" +tblid <- "TSFAE20d" fileid <- write_path(opath, tblid) popfl <- "SAFFL" trtvar <- "TRT01A" @@ -52,15 +28,25 @@ tab_titles <- list( # Filter AE dataframe to include 1st occurenace of a given PT. ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> create_colspan_var( non_active_grp = "Placebo", non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% + ) |> mutate( months = (TRTEDY + 30) / 30.4375, ACAT1 = case_when( @@ -81,7 +67,7 @@ adsl <- adsl_jnj %>% "Beyond 13 months" ) ) - ) %>% + ) |> select( USUBJID, !!rlang::sym(popfl), @@ -91,8 +77,18 @@ adsl <- adsl_jnj %>% ACAT1 ) -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% +adae <- adae_jnj |> + mutate( + AEBODSYS = case_when( + AEBODSYS == "" ~ "Uncoded", + .default = AEBODSYS + ), + AEDECOD = case_when( + AEDECOD == "" ~ paste0("Uncoded: ", AETERM), + .default = AEDECOD + ) + ) |> + filter(TRTEMFL == "Y") |> select( USUBJID, TRTEMFL, @@ -103,7 +99,7 @@ adae <- adae_jnj %>% AOCCFL, AOCCPFL, AOCCSFL - ) %>% + ) |> mutate( ACAT1 = forcats::fct_na_value_to_level(factor( ACAT1, @@ -115,10 +111,10 @@ adae <- adae_jnj %>% "Beyond 13 months" ) )) - ) %>% + ) |> arrange(USUBJID, AEBODSYS, AEDECOD, ASTDT) -adae <- inner_join(adae, adsl %>% select(-ACAT1), by = c("USUBJID")) +adae <- inner_join(adae, adsl |> select(-ACAT1), by = c("USUBJID")) adae$TRTEMFL <- factor(adae$TRTEMFL) @@ -138,13 +134,34 @@ colspan_trt_map <- create_colspan_map( # This df generates facets with cumulative counts for .N_col. Note: These extra # records must then be removed from the numerator by a_freq_combos_j function. combodf <- tribble( - ~valname, ~label, ~levelcombo, ~exargs, - "Total", "Total", c("Within 3 months", "4 to 6 months", "7 to 9 months", "10 to 12 months", "Beyond 13 months", "(Missing)"), list(), - "Thru 3 months", "Within 3 months", c("Within 3 months", "4 to 6 months", "7 to 9 months", "10 to 12 months", "Beyond 13 months"), list(), - "Thru 6 months", "4 to 6 months", c("4 to 6 months", "7 to 9 months", "10 to 12 months", "Beyond 13 months"), list(), - "Thru 9 months", "7 to 9 months", c("7 to 9 months", "10 to 12 months", "Beyond 13 months"), list(), - "Thru 12 months", "10 to 12 months", c("10 to 12 months", "Beyond 13 months"), list(), - "Over 13 months", "Beyond 13 months", c("Beyond 13 months"), list() + ~valname, + ~label, + ~levelcombo, + ~exargs, + "Total", + "Total", + c("Within 3 months", "4 to 6 months", "7 to 9 months", "10 to 12 months", "Beyond 13 months", "(Missing)"), + list(), + "Thru 3 months", + "Within 3 months", + c("Within 3 months", "4 to 6 months", "7 to 9 months", "10 to 12 months", "Beyond 13 months"), + list(), + "Thru 6 months", + "4 to 6 months", + c("4 to 6 months", "7 to 9 months", "10 to 12 months", "Beyond 13 months"), + list(), + "Thru 9 months", + "7 to 9 months", + c("7 to 9 months", "10 to 12 months", "Beyond 13 months"), + list(), + "Thru 12 months", + "10 to 12 months", + c("10 to 12 months", "Beyond 13 months"), + list(), + "Over 13 months", + "Beyond 13 months", + c("Beyond 13 months"), + list() ) @@ -155,12 +172,12 @@ extra_args1 <- list( .stats = "count_unique_fraction" ) -lyt <- basic_table(top_level_section_div = " ") %>% +lyt <- basic_table(top_level_section_div = " ") |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% + ) |> + split_cols_by(trtvar) |> split_cols_by( "ACAT1", split_fun = add_combo_levels( @@ -168,7 +185,7 @@ lyt <- basic_table(top_level_section_div = " ") %>% trim = FALSE, keep_levels = combodf$valname ) - ) %>% + ) |> analyze( popfl, show_labels = "hidden", @@ -177,7 +194,7 @@ lyt <- basic_table(top_level_section_div = " ") %>% label = "Analysis set: Safety", .stats = "n_altdf" ) - ) %>% + ) |> analyze( "TRTEMFL", nested = FALSE, @@ -191,14 +208,14 @@ lyt <- basic_table(top_level_section_div = " ") %>% flag_var = NULL ) ) - ) %>% + ) |> split_rows_by( "AEBODSYS", split_label = "System Organ Class", label_pos = "topleft", split_fun = trim_levels_in_group("AEDECOD"), section_div = c(" ") - ) %>% + ) |> summarize_row_groups( "AEBODSYS", cfun = a_freq_combos_j, @@ -206,7 +223,7 @@ lyt <- basic_table(top_level_section_div = " ") %>% extra_args1, list(flag_var = NULL) ) - ) %>% + ) |> analyze( "AEDECOD", afun = a_freq_combos_j, @@ -214,10 +231,10 @@ lyt <- basic_table(top_level_section_div = " ") %>% extra_args1, list(flag_var = NULL) ) - ) %>% + ) |> append_topleft(" Preferred Term, n (%)") -result <- build_table(lyt, adae, alt_counts_df = adsl) +result <- build_table(lyt, adae, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Prune & sort results @@ -225,14 +242,20 @@ result <- build_table(lyt, adae, alt_counts_df = adsl) result <- safe_prune_table(result, prune_func = bspt_pruner()) -result <- result %>% +result <- result |> sort_at_path( path = c("root", "AEBODSYS"), - scorefun = jj_complex_scorefun(colpath = "Total") - ) %>% + # Provide the entire path below in colpath argument. The paths can be identified using col_paths(result). + scorefun = jj_complex_scorefun( + colpath = c("colspan_trt", "Active Study Agent", "TRT01A", "Xanomeline High Dose", "ACAT1", "Total") + ) + ) |> sort_at_path( path = c("root", "AEBODSYS", "*", "AEDECOD"), - scorefun = jj_complex_scorefun(colpath = "Total") + # Provide the entire path below in colpath argument. The paths can be identified using col_paths(result). + scorefun = jj_complex_scorefun( + colpath = c("colspan_trt", "Active Study Agent", "TRT01A", "Xanomeline High Dose", "ACAT1", "Total") + ) ) ################################################################################ @@ -245,10 +268,10 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table: ################################################################################ -colwidth <- c(64, 21, 17, 21, 19, 21, 23, 21, 21, 21, 21, 21, 19, 21, 19, 17, 19, 21, 19) + +colwidth <- c(64, 21, 19, 21, 21, 19, 21, 21, 19, 19, 19, 19, 21, 21, 19, 17, 21, 19, 19) tt_to_tlgrtf( - colwidths = colwidth, result, file = fileid, orientation = "landscape", diff --git a/tests/testthat/source_code/tsfae24a.R b/tests/testthat/source_code/tsfae24a.R deleted file mode 100644 index 96a364bf..00000000 --- a/tests/testthat/source_code/tsfae24a.R +++ /dev/null @@ -1,144 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae24a.R -## R version: 4.2.1 -## Short Description: Program to create tsfae24a: Overall Summary of -## Treatment-emergent Adverse Events by Severity -## Author: Johnson & Johnson Innovative Medicine -## Date: 13DEC2023 -## Input: adsl.RDS, adae.RDS -## Output: tsfae24a.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFAE24a" -fileid <- write_path(opath, tblid) -popfl <- "SAFFL" -trtvar <- "TRT01A" -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - - -################################################################################ -# Process data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - create_colspan_var( - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar - ) %>% - select(USUBJID, !!rlang::sym(trtvar), colspan_trt) - -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% - mutate( - ASEV = factor( - ifelse(is.na(AESEV), "Missing", as.character(AESEV)), - levels = c("Severe", "Moderate", "Mild", "Missing") - ) - ) %>% - select(USUBJID, TRTEMFL, ASEV) - -ae <- inner_join(adae, adsl, by = c("USUBJID")) - -# Keep maximum severity per subject. -ae <- ae %>% - arrange(USUBJID, ASEV) %>% - group_by(USUBJID) %>% - slice(1) %>% - ungroup() - -################################################################################ -# Define layout and build table: -################################################################################ -extra_args_1 <- list(.stats = c("count_unique_fraction")) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - - -lyt <- basic_table( - show_colcounts = TRUE, - colcount_format = "N=xx", - top_level_section_div = " " -) %>% - append_topleft("n (%)") %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - analyze_num_patients( - vars = "USUBJID", - .stats = "unique", - .formats = c("unique" = jjcsformat_count_fraction), - .labels = "Subjects with >= 1 AE" - ) %>% - analyze( - "ASEV", - afun = a_freq_j, - extra_args = extra_args_1, - var_labels = "Severity", - nested = FALSE, - show_labels = "visible", - ) - -result <- build_table(lyt, ae, alt_counts_df = adsl) - -################################################################################ -# Prune missing category if all zeros: -################################################################################ - -result <- safe_prune_table( - result, - prune_func = count_pruner(cat_include = "Missing") -) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table: -################################################################################ - -colwidth <- c(37, 21, 21, 21) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfae24b.R b/tests/testthat/source_code/tsfae24b.R deleted file mode 100644 index debb5afa..00000000 --- a/tests/testthat/source_code/tsfae24b.R +++ /dev/null @@ -1,160 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae24b.R -## R version: 4.2.1 -## Short Description: Program to create tsfae24b: Overall Summary of -## Treatment-emergent Adverse Events by Toxicity Grade -## Author: Johnson & Johnson Innovative Medicine -## Date: 13DEC2023 -## Input: adsl.RDS, adae.RDS -## Output: tsfae24b.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFAE24b" -fileid <- write_path(opath, tblid) -popfl <- "SAFFL" -trtvar <- "TRT01A" -exclude_G5_if_none <- FALSE -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - - -################################################################################ -# Process data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - create_colspan_var( - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar - ) %>% - select(USUBJID, !!rlang::sym(trtvar), colspan_trt) - -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% - mutate( - ATOXGR = factor( - ifelse(is.na(AETOXGR), "Missing", paste("Grade", as.character(AETOXGR))), - levels = c( - "Grade 5", - "Grade 4", - "Grade 3", - "Grade 2", - "Grade 1", - "Missing" - ) - ) - ) %>% - select(USUBJID, TRTEMFL, ATOXGR) - -ae <- inner_join(adae, adsl, by = c("USUBJID")) - -# Keep maximum toxicity per subject. -ae <- ae %>% - arrange(USUBJID, ATOXGR) %>% - group_by(USUBJID) %>% - slice(1) %>% - ungroup() - -################################################################################ -# Define layout and build table: -################################################################################ - -extra_args_1 <- list(.stats = c("count_unique_fraction")) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -lyt <- basic_table( - show_colcounts = TRUE, - colcount_format = "N=xx", - top_level_section_div = " " -) %>% - append_topleft("n (%)") %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - analyze_num_patients( - vars = "USUBJID", - .stats = "unique", - .formats = c("unique" = jjcsformat_count_fraction), - .labels = "Subjects with >= 1 AE" - ) %>% - analyze( - "ATOXGR", - afun = a_freq_j, - extra_args = extra_args_1, - var_labels = "Toxicity grade", - nested = FALSE, - show_labels = "visible", - ) - - -result <- build_table(lyt, ae, alt_counts_df = adsl) - -################################################################################ -# Prune missing category if all zeros: -################################################################################ - -if (exclude_G5_if_none == TRUE) { - result <- safe_prune_table( - result, - prune_func = count_pruner(cat_include = c("Grade 5", "Missing")) - ) -} else { - result <- safe_prune_table( - result, - prune_func = count_pruner(cat_include = c("Missing")) - ) -} - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table: -################################################################################ - -colwidth <- c(37, 21, 21, 21) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfae24c.R b/tests/testthat/source_code/tsfae24c.R deleted file mode 100644 index c8579afa..00000000 --- a/tests/testthat/source_code/tsfae24c.R +++ /dev/null @@ -1,176 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae24c.R -## R version: 4.2.1 -## Short Description: Program to create tsfae24c: Subjects with -## Treatment-emergent Adverse Events and Related -## Treatment-emergent Adverse Events by SOC/PT -## Author: Johnson & Johnson Innovative Medicine -## Date: 19DEC2023 -## Input: adsl.RDS, adae.RDS -## Output: tsfae24c.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFAE24c" -fileid <- write_path(opath, tblid) -popfl <- "SAFFL" -trtvar <- "TRT01A" -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - - -################################################################################ -# Process data: -# Create variables for column spanning headers: -# - colspan_trt: Used to generate the "Active Study Agent" spanning header. -# - COLSPAN_REL: Set to "AEs" for all subjects. Used along with the add_combo_levels() -# split function to generate separate facets for AEs & Related AEs. -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - create_colspan_var( - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar - ) %>% - mutate(COLSPAN_REL = "AEs") %>% - select( - USUBJID, - !!rlang::sym(popfl), - !!rlang::sym(trtvar), - colspan_trt, - COLSPAN_REL - ) - -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% - select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AEREL) - -adae <- inner_join(adae, adsl, by = c("USUBJID")) - -################################################################################ -# Define layout and build table: -################################################################################ - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -combodf <- tribble( - ~valname, ~label, ~levelcombo, ~exargs, - "RELATED", "Related AEs", c("AEs"), list() -) - -extra_args1 <- list( - .stats = c("count_unique_fraction"), - subcol_split = "RELATED", - subcol_var = "AEREL", - subcol_val = "RELATED" -) - -lyt <- basic_table( - show_colcounts = TRUE, - colcount_format = "N=xx", - top_level_section_div = " " -) %>% - split_cols_by( - "COLSPAN_REL", - split_fun = add_combo_levels(combodf, trim = TRUE) - ) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - analyze( - "TRTEMFL", - afun = a_freq_subcol_j, - extra_args = append( - extra_args1, - list( - label = "Subjects with >= 1 AE", - val = "Y" - ) - ) - ) %>% - split_rows_by( - "AEBODSYS", - split_label = "System Organ Class", - label_pos = "topleft", - split_fun = trim_levels_in_group("AEDECOD"), - section_div = " ", - nested = FALSE - ) %>% - summarize_row_groups( - "AEBODSYS", - cfun = a_freq_subcol_j, - extra_args = extra_args1 - ) %>% - analyze("AEDECOD", afun = a_freq_subcol_j, extra_args = extra_args1) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, adae, alt_counts_df = adsl) - -################################################################################ -# Post-Processing: -# Sort by descending AEBODSYS/AEDECOD in combined AE column -################################################################################ - -result <- result %>% - sort_at_path( - path = c("AEBODSYS"), - scorefun = cont_n_onecol("AEs.Active Study Agent.Xanomeline High Dose") - ) %>% - sort_at_path( - path = c("AEBODSYS", "*", "AEDECOD"), - scorefun = score_occurrences_cols( - "AEs.Active Study Agent.Xanomeline High Dose" - ) - ) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table: -################################################################################ - -colwidth <- c(64, 21, 21, 21, 21, 21, 19) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfae24d.R b/tests/testthat/source_code/tsfae24d.R deleted file mode 100644 index 1f0fc4c1..00000000 --- a/tests/testthat/source_code/tsfae24d.R +++ /dev/null @@ -1,212 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfae24d.R -## R version: 4.2.1 -## Short Description: Program to create tsfae24d: Subjects with Treatment-emergent -## Adverse Events Toxicity Grade 3 or Greater by SOC/PT -## Author: Johnson & Johnson Innovative Medicine -## Date: 27DEC2023 -## Input: adsl.RDS, adae.RDS -## Output: tsfae24d.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFAE24d" -fileid <- write_path(opath, tblid) -popfl <- "SAFFL" -trtvar <- "TRT01A" -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - - -################################################################################ -# Process data: -# Create variables for column spanning headers: -# - colspan_trt: Used to generate the "Active Study Agent" spanning header. -# - COLSPAN_TOX: Set to "AEs" for all subjects. Used along with the add_combo_levels() -# split function to generate separate facets for AEs & AEs with TOXGR > 3. -################################################################################ - -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - create_colspan_var( - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar - ) %>% - mutate(COLSPAN_TOX = "AEs") %>% - select( - USUBJID, - !!rlang::sym(popfl), - !!rlang::sym(trtvar), - colspan_trt, - COLSPAN_TOX - ) - -adae <- adae_jnj %>% - filter(TRTEMFL == "Y") %>% - mutate(TOXGE3 = ifelse(AETOXGRN == 3 | AETOXGRN > 3, ">= 3", "< 3")) %>% - select(USUBJID, TRTEMFL, AEBODSYS, AEDECOD, AETOXGR, TOXGE3) - -adae <- inner_join(adae, adsl, by = c("USUBJID")) - -################################################################################ -# Define layout and build table: -################################################################################ - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -add_active_combo <- make_split_fun( - post = list( - add_combo_facet( - name = "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ), - cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - ) -) - -# Create "TOX > 3" facet. -add_tox_levels <- make_split_fun( - post = list(add_combo_facet( - name = "TOXGR", - label = ">= Grade 3 AEs", - levels = c("AEs") - )) -) - -extra_args1 <- list( - .stats = c("count_unique_fraction"), - subcol_split = "TOXGR", - subcol_var = "TOXGE3", - subcol_val = ">= 3" -) - -lyt <- basic_table(top_level_section_div = " ") %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by( - trtvar, - split_fun = add_active_combo, - show_colcounts = TRUE, - colcount_format = "N=xx" - ) %>% - split_cols_by("COLSPAN_TOX", split_fun = add_tox_levels) %>% - analyze( - "TRTEMFL", - nested = FALSE, - afun = a_freq_subcol_j, - extra_args = append( - extra_args1, - list( - label = "Subjects with >= 1 AE", - val = "Y" - ) - ) - ) %>% - split_rows_by( - "AEBODSYS", - split_label = "System Organ Class", - label_pos = "topleft", - split_fun = trim_levels_in_group("AEDECOD"), - section_div = " ", - nested = FALSE - ) %>% - summarize_row_groups( - "AEBODSYS", - cfun = a_freq_subcol_j, - extra_args = extra_args1 - ) %>% - analyze("AEDECOD", afun = a_freq_subcol_j, extra_args = extra_args1) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, adae, alt_counts_df = adsl) - -################################################################################ -# Post-Processing: -# Sort by descending AEBODSYS/AEDECOD in combined TOXGR AE column -# Prune table to only keep those that meet x% criteria -################################################################################ - -result <- result %>% - sort_at_path( - path = c("AEBODSYS"), - scorefun = cont_n_onecol("Active Study Agent.Combined.TOXGR") - ) %>% - sort_at_path( - path = c("AEBODSYS", "*", "AEDECOD"), - scorefun = score_occurrences_cols("Active Study Agent.Combined.TOXGR") - ) - -row_condition <- has_fraction_in_any_col( - atleast = .02, - col_names = c( - "Active Study Agent.Xanomeline High Dose.TOXGR", - "Active Study Agent.Xanomeline Low Dose.TOXGR", - "Active Study Agent.Combined.TOXGR", - " .Placebo.TOXGR" - ) -) - -result <- safe_prune_table(result, keep_rows(row_condition)) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table: -################################################################################ - -colwidth <- c(64, 21, 21, 21, 21, 23, 21, 21, 21) - -tt_to_tlgrtf( - colwidths = colwidth, - result, - file = fileid, - orientation = "landscape", - nosplitin = list(cols = c(trtvar)) -) diff --git a/tests/testthat/source_code/tsfdth01.R b/tests/testthat/source_code/tsfdth01.R index 487f0aab..b197a20b 100644 --- a/tests/testthat/source_code/tsfdth01.R +++ b/tests/testthat/source_code/tsfdth01.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfdth01.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsfdth01: Table of deaths -## Author: Johnson & Johnson Innovative Medicine -## Date: 15 Jan 2024 -## Input: ADSL -## Output: TSFDTH01.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -59,6 +35,9 @@ popfl <- "SAFFL" days <- 30 dthcausevar <- "DTHCAUS" +# Either Combined column or highest JnJ Dose level based on study +sort_colpath <- "Combined" + combined_colspan_trt <- TRUE risk_diff <- TRUE rr_method <- "wald" @@ -87,8 +66,8 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> # remove DTHB60FL variable from below if Deaths within 60 days section is not required select( STUDYID, @@ -97,40 +76,45 @@ adsl <- adsl_jnj %>% all_of(popfl), DTHFL, DTHTRTFL, - DTHB60FL, DTHAFTFL, + DTHB60FL, all_of(dthcausevar) - ) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -if (risk_diff == TRUE) { - adsl$rrisk_header <- "Risk Difference (%) (95% CI)" - adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) -} - -adsl <- adsl %>% + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = "Placebo", + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) |> + mutate( + rrisk_header = "Risk Difference (%) (95% CI)", + rrisk_label = paste(!!rlang::sym(trtvar), "vs Placebo") + ) |> mutate( - DTHVAR = !!as.name(dthcausevar), - DTHVAR = as.factor(DTHVAR) + DTHVAR = !!as.name(dthcausevar) ) -# re-order so OTHER becomes the last category in the table (if there is an OTHER) -is_other <- adsl %>% - filter(DTHVAR == "OTHER") - -if (length(is_other$DTHVAR) != 0) { - adsl <- adsl %>% - mutate(DTHVAR = forcats::fct_relevel(DTHVAR, "OTHER", after = Inf)) -} # Convert Reasons to sentence case adsl$DTHVAR <- stringr::str_to_sentence(adsl$DTHVAR) adsl$DTHVAR <- as.factor(adsl$DTHVAR) + +################################################################################ +# Define layout and build table: +################################################################################ + colspan_trt_map <- create_colspan_map( adsl, non_active_grp = ctrl_grp, @@ -139,11 +123,9 @@ colspan_trt_map <- create_colspan_map( colspan_var = "colspan_trt", trt_var = trtvar ) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) -################################################################################ -# Define layout and build table: -################################################################################ + +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) extra_args_rr <- list( method = rr_method, @@ -154,30 +136,30 @@ extra_args_rr <- list( ) # check if we actually have any deaths so this can be used for the layout -anydth <- adsl %>% +anydth <- adsl |> filter(DTHFL == "Y") lyt <- basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } if (risk_diff == TRUE) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", @@ -186,19 +168,19 @@ if (risk_diff == TRUE) { } if (length(anydth$DTHFL) != 0) { - lyt <- lyt %>% + lyt <- lyt |> split_rows_by( "DTHFL", split_fun = keep_split_levels("Y"), split_label = "Deaths", label_pos = "topleft", section_div = " " - ) %>% + ) |> summarize_row_groups( "DTHFL", cfun = a_freq_j, extra_args = append(extra_args_rr, list(label = "Total deaths")) - ) %>% + ) |> analyze( "DTHVAR", var_labels = " ", @@ -206,12 +188,12 @@ if (length(anydth$DTHFL) != 0) { extra_args = extra_args_rr, indent_mod = 0, show_labels = "hidden" - ) %>% + ) |> split_rows_by( "DTHTRTFL", split_fun = keep_split_levels("Y"), section_div = " " - ) %>% + ) |> summarize_row_groups( "DTHTRTFL", cfun = a_freq_j, @@ -219,7 +201,7 @@ if (length(anydth$DTHFL) != 0) { extra_args_rr, list(label = paste0("Deaths within ", days, " days of last dose")) ) - ) %>% + ) |> analyze( "DTHVAR", var_labels = " ", @@ -227,12 +209,12 @@ if (length(anydth$DTHFL) != 0) { extra_args = extra_args_rr, indent_mod = 0, show_labels = "hidden" - ) %>% + ) |> split_rows_by( "DTHAFTFL", split_fun = keep_split_levels("Y"), section_div = " " - ) %>% + ) |> summarize_row_groups( "DTHAFTFL", cfun = a_freq_j, @@ -240,7 +222,7 @@ if (length(anydth$DTHFL) != 0) { extra_args_rr, list(label = paste0("Deaths beyond ", days, " days of last dose")) ) - ) %>% + ) |> analyze( "DTHVAR", var_labels = " ", @@ -248,13 +230,13 @@ if (length(anydth$DTHFL) != 0) { extra_args = extra_args_rr, indent_mod = 0, show_labels = "hidden" - ) %>% + ) |> # Remove below section if the Deaths within 60 days section is not required split_rows_by( "DTHB60FL", split_fun = keep_split_levels("Y"), section_div = " " - ) %>% + ) |> summarize_row_groups( "DTHB60FL", cfun = a_freq_j, @@ -262,7 +244,7 @@ if (length(anydth$DTHFL) != 0) { extra_args_rr, list(label = "Deaths within 60 days of first dose") ) - ) %>% + ) |> analyze( "DTHVAR", var_labels = " ", @@ -272,7 +254,7 @@ if (length(anydth$DTHFL) != 0) { show_labels = "hidden" ) } else { - lyt <- lyt %>% + lyt <- lyt |> analyze( "DTHFL", a_freq_j, @@ -281,10 +263,10 @@ if (length(anydth$DTHFL) != 0) { ) } -lyt <- lyt %>% - append_topleft(" Cause of Death, n (%)") +lyt <- lyt |> + append_topleft(" Primary Cause of Death, n (%)") -result <- build_table(lyt, adsl, alt_counts_df = adsl) +result <- build_table(lyt, adsl, alt_counts_df = adsl, round_type = "sas") ## Remove the N=xx column headers for the risk difference columns result <- remove_col_count(result) @@ -308,22 +290,22 @@ if (length(anydth$DTHFL) != 0) { result <- sort_at_path( result, c("root", "DTHFL", "*", "DTHVAR"), - scorefun = jj_complex_scorefun() + scorefun = jj_complex_scorefun(colpath = sort_colpath, lastcat = "count_unique_fraction.Other") ) result <- sort_at_path( result, c("root", "DTHTRTFL", "*", "DTHVAR"), - scorefun = jj_complex_scorefun() + scorefun = jj_complex_scorefun(colpath = sort_colpath, lastcat = "count_unique_fraction.Other") ) result <- sort_at_path( result, c("root", "DTHAFTFL", "*", "DTHVAR"), - scorefun = jj_complex_scorefun() + scorefun = jj_complex_scorefun(colpath = sort_colpath, lastcat = "count_unique_fraction.Other") ) result <- sort_at_path( result, c("root", "DTHB60FL", "*", "DTHVAR"), - scorefun = jj_complex_scorefun() + scorefun = jj_complex_scorefun(colpath = sort_colpath, lastcat = "count_unique_fraction.Other") ) } @@ -337,6 +319,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(57, 5, 17, 17, 17, 29, 29) + +colwidth <- c(57, 17, 17, 17, 17, 29, 29) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfecg01.R b/tests/testthat/source_code/tsfecg01.R index 4eff1e98..083bfaca 100644 --- a/tests/testthat/source_code/tsfecg01.R +++ b/tests/testthat/source_code/tsfecg01.R @@ -1,40 +1,27 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfecg01 -## R version: 4.2.1 -## Short Description: Program to create tsfecg01: Mean Change From Baseline -## for ECG Data Over Time -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adeg.RDS -## Output: tsfecg01.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(haven) +library(stringr) ################################################################################ # Define script level parameters: ################################################################################ +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Define control group label +# - Define ECG parameters and non-baseline visits to include +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +################################################################################ + tblid <- "TSFECG01" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" @@ -44,23 +31,18 @@ popfl <- "SAFFL" trtvar <- "TRT01A" ctrl_grp <- "Placebo" -# Note on ancova parameter -# when ancova = TRUE -# ancova model will be used to calculate all mean/mean change columns -# not just those from the Difference column -# model specification -summ_vars <- list(arm = trtvar, covariates = NULL) - -# when ancova = FALSE, all mean/mean change columns will be from descriptive stats -# for the difference column descriptive stats will be based upon two-sample t-test -ancova <- FALSE +# Add Active Study Agent Combined column? +combined_colspan_trt <- TRUE +# Flag to enable comparison between treatment groups (e.g., mean difference vs. placebo). comp_btw_group <- TRUE -selparamcd <- c("EGHRMN", "PRAG", "QRSAG", "QTC", "QTCBAG", "QTCFAG", "RRAG") -# see further, an alternative method to identify all non-unscheduled visits based upon data -selvisit <- c( - "Baseline", +# ECG parameters of interest (PARAMCD values) + +selparamcd <- c("EGHRMN", "QTC", "QTCBAG", "QTCFAG", "RRAG", "QRSAG", "PRAG") + +# Non-baseline visits of interest (AVISIT values, excluding Baseline) +nonbl_visits <- c( "Month 1", "Month 3", "Month 6", @@ -71,292 +53,406 @@ selvisit <- c( "Month 24" ) + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select( - STUDYID, - USUBJID, - all_of(c(popfl, trtvar)), - SEX, - AGEGR1, - RACE, - ETHNIC, - AGE +adsl <- adsl_jnj |> + select(STUDYID, USUBJID, all_of(c(popfl, trtvar))) |> + filter( + toupper(.data[[popfl]]) == "Y", + !is.na(.data[[trtvar]]) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar ) -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) +adeg <- adeg_jnj -adsl$rrisk_header <- "Difference in Mean Change (95% CI)" -adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) +### available ECG parameters in study +selparamcd <- intersect(selparamcd, unique(adeg$PARAMCD)) -adeg00 <- adeg_jnj %>% +adeg <- adeg |> select( + STUDYID, USUBJID, + all_of(c(popfl, trtvar)), AVISITN, AVISIT, PARAMCD, PARAM, + PARAMN, AVAL, BASE, CHG, starts_with("ANL"), ABLFL, - APOBLFL - # ,EGSTAT - ) %>% - inner_join(adsl) - -# selection of all non-unscheduled visits from data -visits <- adeg00 %>% - select(AVISIT) %>% - filter(!grepl("UNSCHEDULED", toupper(AVISIT))) - -visits$AVISIT <- droplevels(visits$AVISIT) -selvisit_data <- levels(visits$AVISIT) - -### if preferred to get it from data, rather than hardcoded list of visits -# selvisit <- selvisit_data - -## retrieve the precision of AVAL on the input dataset -## review outcome and make updates manually if needed -## the precision variable will be used for the parameter-based formats in layout - -## decimal = 4 is a cap in this derivation: if decimal precision of variable > decimal, the result will end up as decimal -## eg if AVAL has precision of 6 for parameter x, and decimal = 4, the resulting decimal value for parameter x is 4 - -## note that precision is on the raw values, as we are presenting mean/ci, and extra digit will be added -## eg precision = 2 will result in mean/ci format xx.xxx (xx.xxx, xx.xxx) + APOBLFL, + DTYPE + ) |> + filter( + !is.na(USUBJID), + .data[[popfl]] == "Y", + !is.na(.data[[trtvar]]), + PARAMCD %in% selparamcd + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) -eg_precision <- tidytlg:::make_precision_data( - df = adeg00, - decimal = 4, - precisionby = "PARAMCD", - precisionon = "AVAL" +# restrict to these - ordered by PARAMN +selparamcd <- as.character( + adeg |> arrange(PARAMN) |> pull(PARAMCD) |> unique() ) -### data preparation - -filtered_adeg <- adeg00 %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) +adeg <- adeg |> + mutate( + ABLFL := factor(ifelse(!is.na(ABLFL) & ABLFL == "Y", "Y", "N")), + APOBLFL := factor(ifelse(!is.na(APOBLFL) & APOBLFL == "Y", "Y", "N")), + PARAMCD := factor(PARAMCD, levels = selparamcd), + PARAM := factor(PARAM), + # Baseline records: label AVISIT as "Baseline" using ABLFL flag + AVISIT := factor( + ifelse(ABLFL == "Y" & !is.na(ABLFL), "Baseline", as.character(AVISIT)), + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) -## issue with sysntethic data for Xanomeline Low Dose : 600 records rather than 300 -check1 <- filtered_adeg %>% - group_by(TRT01A, PARAM, AVISIT) %>% - summarize(n_rec = n(), n_sub = n_distinct(USUBJID)) +nonbl_visits <- unique(as.character(adeg$AVISIT[adeg$AVISIT %in% nonbl_visits])) +adeg <- inner_join(adsl, adeg, by = c("STUDYID", "USUBJID", popfl, trtvar)) -#### perform check on unique record per subject/param/timepoint -check_unique <- filtered_adeg %>% - group_by(USUBJID, PARAMCD, AVISIT) %>% - mutate(n_recsub = n()) %>% +# Safety check: unique record per subject/parameter/visit +adeg_check_unique <- adeg |> + filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) |> + group_by(USUBJID, PARAMCD, AVISIT) |> + mutate(n_recsub = n()) |> filter(n_recsub > 1) -if (nrow(check_unique) > 0) { +if (nrow(adeg_check_unique) > 0) { stop( "Your input dataset needs extra attention, as some subjects have more than one record per parameter/visit" ) - ### you will run into issues with fraction portion in count_denom_fraction, as count > denom, and fraction > 1 if you don't adjust your input dataset - - # Possible extra derivation - just to ensure program can run without issues - ### Study team is responsible for adding this derivation onto ADaM dataset and ensure proper derivation rule for ANL02FL is implemented !!!!!!!!!! - filtered_adegx <- adeg00 %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) %>% - group_by(USUBJID, PARAM, AVISIT) %>% - mutate(n_sub = n()) %>% - arrange(USUBJID, PARAM, AVISIT, ADT) %>% - mutate(i = vctrs::vec_group_id(ADT)) %>% - mutate( - ANL02FL = case_when( - n_sub == 1 ~ "Y", - i == 1 ~ "Y" - ) - ) %>% - select(-c(i, n_sub)) %>% - ungroup() - - filtered_adeg <- filtered_adegx %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) - - ## now your data should contain 1 record per subject per parameter } -### for denominator per timepoint: all records from adeg on this timepoint: ignoring anl01fl/anl02fl/param -filtered_adeg_timepoints <- unique( - adeg00 %>% - filter(AVISIT %in% selvisit) %>% - select(USUBJID, AVISITN, AVISIT) -) %>% - inner_join(adsl) - -params <- unique(filtered_adeg %>% select(PARAMCD, PARAM)) +adeg_checked <- adeg |> + filter( + toupper(.data[[popfl]]) == "Y", + toupper(ANL01FL) == "Y", + toupper(ANL02FL) == "Y" + ) |> + mutate( + flag = if_else(is.na(AVAL), 1L, 0L), + flag1 = if_else(toupper(APOBLFL) == "Y" & is.na(BASE), 1L, 0L) + ) -filtered_adeg_timepoints <- filtered_adeg_timepoints %>% - mutate(dummy_join = 1) %>% - full_join( - params %>% mutate(dummy_join = 1), - relationship = "many-to-many" - ) %>% - select(-dummy_join) +if (nrow(filter(adeg_checked, flag == 1)) > 0) { + stop("Pay attention: There are tests with missing AVAL: ") +} -### identify subjects in filtered_advs_timepoints and not in filtered_advs +if (nrow(filter(adeg_checked, flag1 == 1)) > 0) { + stop("Pay attention: There are postbaseline tests without baseline: ") +} -extra_sub <- anti_join(filtered_adeg_timepoints, filtered_adeg) +# Keep only records with non-missing AVAL +adeg <- filter(adeg, !is.na(AVAL)) -### only add these extra_sub to -### this will ensure we still meet the one record per subject per timepoint -### this will ensure length(x) can be used for the denominator derivation inside summarize_aval_chg_diff function -filtered_adeg <- bind_rows(filtered_adeg, extra_sub) %>% - arrange(USUBJID, PARAM, AVISITN) +################################################################################ +# Formats for decimal precision control +################################################################################ -filtered_adeg <- filtered_adeg %>% - inner_join(eg_precision, by = "PARAMCD") +# manual setup example for user +prec <- dplyr::tibble(PARAMCD = selparamcd, d = 1) +prec$d[prec$PARAMCD == "EGHRMN"] <- 0 + +# alternative: use tidytlg make_precision function +# cutoff for decimal is defined in function and if DTYPE="AVERAGE" those records excluded from precison + +# adeg_avg <- adeg |> filter(!DTYPE=="AVERAGE") + +# prec2 <- tidytlg:::make_precision_data( +# df = adeg_avg, +# decimal = 4, +# precisionby = "PARAMCD", +# precisionon = "AVAL" +# ) |> +# rename(c(d = "decimal")) + +.stats_all <- c("n", "mean_sd", "median_range", "diff_means_est_ci") +# add d-based formats for all required stats onto precision dataset +prec <- fmt_spec_df_d( + prec, # If using alternative method of precison add that dataset here + d_column = "d", + fmt_column = "fmt_d", + stats_in = .stats_all, + fmt_d_def = junco_def_d_all, + fmt_d_in = NULL +) -### important: previous actions lost the label of variables -### in order to be able to use obj_label(filtered_advs$PARAM) in layout, need to redefine the label -filtered_adeg <- var_relabel_list(filtered_adeg, var_labels(adeg00, fill = T)) +# If user wanted to review d-based formats below code should be used -check1 <- filtered_adeg %>% - group_by(TRT01A, PARAM, AVISIT) %>% - summarize(n_rec = n(), n_sub = n_distinct(USUBJID)) +# fmt_d_details <- lapply(prec$PARAMCD, +# FUN = function(x) { +# fmt <- prec[prec$PARAMCD == x,][["fmt_d"]][[1]] +# get_fmt_details( +# fmt, +# as_tibble = TRUE) +# } +# ) +# names(fmt_d_details) <- prec$PARAMCD +# fmt_d_details -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) +# add precision specific format to adeg input dataset +adeg <- adeg |> + left_join(prec) ################################################################################ # Define layout and build table: ################################################################################ -summ_vars <- list(arm = trtvar, covariates = NULL) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) -multivars <- c("AVAL", "AVAL", "CHG") - -extra_args_3col <- list( - format_na_str = rep("NA", 3), - d = "decimal", - variables = summ_vars, - ref_path = ref_path, - ancova = ancova, - comp_btw_group = comp_btw_group, - multivars = multivars -) +colspan_trt_map <- if (!is.null(ctrl_grp)) { + create_colspan_map( + adeg, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) +} else { + tibble( + colspan_trt = "Active Study Agent", + !!trtvar := levels(adeg[[trtvar]]) + ) +} + +# Common stats for Baseline / Timepoint / Change sections +stats <- c("n", "mean_sd", "median_range") +labels <- junco_get_labels_from_stats(stats, labels_in = c(n = "N")) +indent_mods <- c(n = 1L, mean_sd = 2L, median_range = 2L) + +# Dynamic "Change from baseline to " section label +a_chg_label <- function(x, .spl_context) { + last_split <- length(.spl_context$split) + label <- paste("Change from baseline to", .spl_context$value[last_split]) + rtables::rcell(NULL, label = label) +} + +# Difference in means parameters. +CI_cl <- tern::control_analyze_vars()$conf_level +a_diff_means_args <- list( + ref_path = c("colspan_trt", " ", trtvar, ctrl_grp), + conf.level = CI_cl, + .stats = "diff_means_est_ci", + .formats = "default", + # .formats = c(diff_means_est_ci = jjcsformat_xx("xx.xx (xx.xx, xx.xx)")), + .labels = c( + diff_means_est_ci = paste0( + "Difference in mean [vs. ", + str_to_lower(ctrl_grp), + "]", + " (", + tern::f_conf_level(CI_cl), + ")" + ) + ) +) -lyt <- basic_table(show_colcounts = FALSE, colcount_format = "N=xx") %>% - ### first columns +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx", + top_level_section_div = " " +) |> + append_topleft("Parameter") |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar, show_colcounts = TRUE, colcount_format = "N=xx") %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +# Row split by PARAM (PARAM/PARAMN label per mock annotation) +lyt <- lyt |> split_rows_by( - "PARAM", - label_pos = "topleft", - split_label = obj_label(filtered_adeg$PARAM), - section_div = " ", - split_fun = drop_split_levels - ) %>% - ## note the child_labels = hidden for AVISIT, these labels will be taken care off by - ## applying function summarize_aval_chg_diff further in the layout + "PARAMCD", + split_fun = keep_split_levels(selparamcd), + labels_var = "PARAM", + child_labels = "visible" + ) |> + # ── Baseline section (ABLFL = "Y") ────────────────────────────────────────── + summarize_row_groups( + "AVAL", + cfun = c_summary_subset_label, + extra_args = list( + filter_expr = expression(ABLFL == "Y"), + .stats = stats, + .formats = "default", + formats_var = "fmt_d", + .labels = labels, + .indent_mods = indent_mods, + label = "Baseline" + ) + ) |> + # ── Non-baseline timepoints (APOBLFL = "Y" & ANL02FL = "Y") ───────────────── split_rows_by( "AVISIT", - label_pos = "topleft", - split_label = "Study Visit", - split_fun = drop_split_levels, - child_labels = "hidden" - ) %>% - ## set up a 3 column split - split_cols_by_multivar( - multivars, - varlabels = c( - "n/N (%)", - "Mean (95% CI)", - "Mean Change From Baseline (95% CI)" - ) - ) %>% - ### restart for the rrisk_header columns - note the nested = FALSE option - ### also note the child_labels = "hidden" in both PARAM and AVISIT - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - split_fun = remove_split_levels(ctrl_grp), - labels_var = "rrisk_label", - show_colcounts = TRUE, - colcount_format = "N=xx" - ) %>% - ### difference columns : just 1 column & analysis needs to be done on change - split_cols_by_multivar(multivars[3], varlabels = c(" ")) %>% - ### the variable passed here in analyze is not used (STUDYID), it is a dummy var passing, - ### the function summarize_aval_chg_diff grabs the required vars from cols_by_multivar calls + split_fun = keep_split_levels(nonbl_visits), + indent_mod = -1, + section_div = " " + ) |> + # Timepoint: Mean (SD) and Median (min, max) of AVAL + analyze( + "AVAL", + afun = tern::a_summary, + extra_args = list( + .stats = stats, + .formats = "default", + .labels = labels, + .indent_mods = indent_mods - 1L, + na_rm = TRUE + ), + formats_var = "fmt_d", + show_labels = "hidden", + section_div = " " + ) |> + # Change from baseline section label (dynamic: "Change from baseline to ") + analyze( + "CHG", + afun = a_chg_label, + table_names = "chg_bl_label", + show_labels = "hidden", + indent_mod = -1L + ) |> + # N for change (subjects with non-missing CHG) analyze( - "STUDYID", - afun = a_summarize_aval_chg_diff_j, - extra_args = extra_args_3col + "CHG", + afun = tern::a_summary, + extra_args = list( + .stats = "n", + .formats = "default", + .labels = labels, + na_rm = TRUE + ), + formats_var = "fmt_d", + show_labels = "hidden" + ) |> + # Baseline mean (SD) — among subjects with non-missing CHG + analyze( + "BASE", + afun = a_summary_subset, + extra_args = list( + filter_expr = expression(!is.na(CHG)), + na_rm = TRUE, + .stats = "mean_sd", + .formats = "default", + .labels = c(mean_sd = "Baseline mean (SD)") + ), + table_names = "chg_bl_mean", + show_labels = "hidden", + indent_mod = 1L, + formats_var = "fmt_d" + ) |> + # Mean (SD) and Median (min, max) of CHG + analyze( + "CHG", + afun = tern::a_summary, + extra_args = list( + .stats = c("mean_sd", "median_range"), + .formats = "default", + .labels = labels, + na_rm = TRUE + ), + formats_var = "fmt_d", + table_names = "chg_mm", + show_labels = "hidden", + indent_mod = 1L ) -result <- build_table(lyt, filtered_adeg, alt_counts_df = adsl) - -################################################################################ -# Post-Processing: -# - Remove the N=xx column headers for the difference vs PBO columns -################################################################################ +if (comp_btw_group) { + lyt <- lyt |> + # Difference in mean [vs placebo] (95% CI) — active arms only + analyze( + "CHG", + afun = a_diff_means, + extra_args = a_diff_means_args, + formats_var = "fmt_d", + table_names = "chg_diff_means", + show_labels = "hidden", + indent_mod = 1L + ) +} -remove_col_count2 <- function(result, string = paste("vs", ctrl_grp)) { - mcdf <- make_col_df(result, visible_only = FALSE) - mcdfsel <- mcdf %>% - filter(stringr::str_detect(toupper(label), toupper(string))) %>% - pull(path) +result <- build_table(lyt, adeg, alt_counts_df = adsl, round_type = "sas") - for (i in seq_along(mcdfsel)) { - facet_colcount(result, mcdfsel[[i]]) <- NA - } - return(result) -} +# Add empty line after each Baseline section (workaround for missing section_div +# in summarize_row_groups; see https://github.com/insightsengineering/rtables/issues/1083) +section_div_at_path(result, c("PARAMCD", "*", "@content", last(stats))) <- " " -result <- remove_col_count2(result) ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(56, 29, 36, 39, 29, 36, 41, 29, 36, 37, 41, 41) -tt_to_tlgrtf( - colwidths = colwidth, - result, - file = fileid, - nosplitin = list(cols = c(trtvar, "rrisk_header")), - orientation = "landscape" -) +colwidth <- c(64, 40, 43, 38, 39) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfecg01a.R b/tests/testthat/source_code/tsfecg01a.R index 53e311c2..9a8a5929 100644 --- a/tests/testthat/source_code/tsfecg01a.R +++ b/tests/testthat/source_code/tsfecg01a.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfecg01 -## R version: 4.2.1 -## Short Description: Program to create tsfecg01: Mean Change From Baseline -## for ECG Data Over Time by [Subgroup] -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adeg.RDS -## Output: tsfecg01.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -437,10 +413,10 @@ result <- set_titles(result, titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(56, 29, 36, 41, 29, 36, 41, 29, 36, 41, 41, 41) + +colwidth <- c(56, 29, 38, 41, 29, 36, 41, 29, 36, 37, 41, 41) tt_to_tlgrtf( - colwidths = colwidth, result, file = fileid, nosplitin = list(cols = c(trtvar, "rrisk_header")), diff --git a/tests/testthat/source_code/tsfecg02.R b/tests/testthat/source_code/tsfecg02.R index 1b52f03d..a0eae20b 100644 --- a/tests/testthat/source_code/tsfecg02.R +++ b/tests/testthat/source_code/tsfecg02.R @@ -1,40 +1,25 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfecg02 -## R version: 4.2.1 -## Short Description: Program to create tsfecg02: Categorized Corrected -## QT Interval Values Over Time -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adeg.RDS -## Output: tsfecg02.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(haven) ################################################################################ # Define script level parameters: ################################################################################ +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Define control group label +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +################################################################################ + tblid <- "TSFECG02" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" @@ -44,7 +29,12 @@ popfl <- "SAFFL" trtvar <- "TRT01A" ctrl_grp <- "Placebo" -selparamcd <- c("QTC", "QTCBAG", "QTCFAG") +# Add Active Study Agent Combined column? +combined_colspan_trt <- TRUE + +selparamcd <- c("QTCFAG", "QTCBAG", "QTCS") + + selvisit <- c( "Baseline", "Month 1", @@ -54,46 +44,115 @@ selvisit <- c( "Month 12" ) +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> select( + STUDYID, USUBJID, - all_of(c(popfl, trtvar)), - SEX_DECODE, - AGEGR1, - RACE_DECODE, - ETHNIC_DECODE + all_of(c(popfl, trtvar)) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) + +filtered_adeg <- adeg_jnj + +### available QT Interval parameters in study +selparamcd <- intersect(selparamcd, unique(filtered_adeg$PARAMCD)) + +filtered_adeg <- filtered_adeg |> + filter( + !is.na(USUBJID), + .data[[popfl]] == "Y", + !is.na(.data[[trtvar]]), + PARAMCD %in% selparamcd, + AVISIT %in% selvisit, + !is.na(AVALCAT1), + ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y") + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) ) -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) +# restrict to these - ordered by PARAMN +selparamcd <- as.character( + filtered_adeg |> arrange(PARAMN) |> pull(PARAMCD) |> unique() +) -filtered_adeg <- adeg_jnj %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - filter(ANL02FL == "Y") %>% - filter(!is.na(AVALCAT1)) %>% +filtered_adeg <- filtered_adeg |> + mutate( + ABLFL := factor(ifelse(!is.na(ABLFL) & ABLFL == "Y", "Y", "N")), + APOBLFL := factor(ifelse(!is.na(APOBLFL) & APOBLFL == "Y", "Y", "N")), + PARAMCD := factor(PARAMCD, levels = selparamcd), + PARAM := factor(PARAM), + AVISIT = factor( + ifelse(ABLFL == "Y" & !is.na(ABLFL), "Baseline", as.character(AVISIT)), + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) |> select( STUDYID, USUBJID, PARAMCD, PARAM, + PARAMN, AVALCAT1, AVALCA1N, AVISIT, ANL02FL, APOBLFL, ABLFL, - ONTRTFL - ) %>% - inner_join(adsl) + ONTRTFL, + all_of(c(popfl, trtvar)), + ) |> + inner_join(adsl, by = c("STUDYID", "USUBJID", popfl, trtvar)) + +selvisit <- unique(as.character(filtered_adeg$AVISIT[filtered_adeg$AVISIT %in% selvisit])) ## main analysis variable is AVALCAT1 : these have the same levels for all selected parameters ## no need to create an map dataframe for usage in layout @@ -107,7 +166,6 @@ colspan_trt_map <- create_colspan_map( trt_var = trtvar ) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) ################################################################################ # Define layout and build table: @@ -118,26 +176,35 @@ extra_args_rr <- list( denom = "n_df", .stats = c("denom", "count_unique_fraction") ) -# extra_args_rr2 <- list(method = "wald", denom = "n_df", .stats = c("denom", "count_unique_denom_fraction")) # version with explicit denominator (usefull for testing purpose) lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +lyt <- lyt |> split_rows_by( - "PARAM", + "PARAMCD", + labels_var = "PARAM", label_pos = "topleft", child_labels = "default", split_label = "QTc Interval", section_div = " ", ## ensure only selected params are included split_fun = drop_split_levels - ) %>% + ) |> split_rows_by( "AVISIT", label_pos = "topleft", @@ -146,18 +213,19 @@ lyt <- basic_table( section_div = " ", ## ensure only the selected visits are included split_fun = drop_split_levels - ) %>% + ) |> analyze( "AVALCAT1", a_freq_j, extra_args = extra_args_rr, show_labels = "hidden", indent_mod = 0L - ) %>% - append_topleft(c(" Criteria, n (%)")) + ) |> + append_topleft(c(" Criteria, n (%)")) -result <- build_table(lyt, filtered_adeg, alt_counts_df = adsl) +result <- build_table(lyt, filtered_adeg, alt_counts_df = adsl, round_type = "sas") + ################################################################################ # Post-Processing: @@ -166,17 +234,17 @@ result <- build_table(lyt, filtered_adeg, alt_counts_df = adsl) result <- remove_col_count(result) - ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(54, 21, 21, 21) + +colwidth <- c(51, 21, 21, 21, 21) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfecg03.R b/tests/testthat/source_code/tsfecg03.R index b0ba71cc..2a7895fc 100644 --- a/tests/testthat/source_code/tsfecg03.R +++ b/tests/testthat/source_code/tsfecg03.R @@ -1,32 +1,9 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfecg03 -## R version: 4.2.1 -## Short Description: Program to create tsfecg03: Categorized Change From -## Baseline to Maximum On-treatment Corrected QT Interval -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adeg.RDS -## Output: tsfecg03.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(haven) ################################################################################ # Define script level parameters: @@ -34,7 +11,7 @@ library(junco) tblid <- "TSFECG03" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" @@ -44,90 +21,107 @@ popfl <- "SAFFL" trtvar <- "TRT01A" ctrl_grp <- "Placebo" -ad_domain <- "adeg" - -selvisit <- c( - "Baseline", - "Month 1", - "Month 3", - "Month 6", - "Month 9", - "Month 12", - "Month 15", - "Month 18", - "Month 24" -) +# Add Active Study Agent Combined column? +combined_colspan_trt <- TRUE ## selection of QTC parameters -selparamcd <- c("QTCFAG", "QTCBAG", "QTCS", "QTCLAG") - -################################################################################ -# initial read of data -################################################################################ +selparamcd <- c("QTCBAG", "QTCFAG", "QTCS", "QTCLAG") -adeg_complete <- adeg_jnj -### available QTC parameters in study -selparamcd <- intersect(selparamcd, unique(adeg_complete$PARAMCD)) +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) -catvar <- "CHGCAT1" -## all parameters have the same levels for CHGCAT1 -- there is no need to create a map dataframe + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select(USUBJID, all_of(c(popfl, trtvar))) - - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -adsl$rrisk_header <- "Risk Difference (%) (95% CI)" -adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) - - -adeg <- adeg_complete %>% - filter(PARAMCD %in% selparamcd) %>% - # filter(AVISIT %in% selvisit) %>% - ### Maximum On-treatment - ### note: by filter ANL03FL, this table is restricted to On-treatment values, per definition of ANL03FL - ### therefor, no need to add ONTRTFL in filter - ### if derivation of ANL03FL is not restricted to ONTRTFL records, adding ONTRTFL here will not give the correct answer either - ### as mixing worst with other period is not giving the proper selection !!! - filter(ANL03FL == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> select( + STUDYID, + USUBJID, + all_of(c(popfl, trtvar)) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) + +adeg <- adeg_jnj + +### available QT Interval parameters in study +selparamcd <- intersect(selparamcd, unique(adeg$PARAMCD)) + +adeg <- adeg |> + filter( + !is.na(USUBJID), + .data[[popfl]] == "Y", + !is.na(.data[[trtvar]]), + PARAMCD %in% selparamcd, + ### Maximum On-treatment + ### note: by filter ANL03FL, this table is restricted to On-treatment values, per definition of ANL03FL + ANL03FL == "Y" + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select( + STUDYID, USUBJID, - ONTRTFL, - TRTEMFL, PARAM, + PARAMN, PARAMCD, - AVISITN, - AVISIT, - AVAL, - BASE, - CHG, - CRIT1, - CRIT1FL, - CRIT2, - CRIT2FL, - all_of(catvar), - ONTRTFL, - TRTEMFL, - ANL01FL, - ANL02FL - ) %>% - inner_join(., adsl) - - -check1 <- adeg %>% - group_by(TRT01A, PARAMCD, AVISIT) %>% - summarize(n = n_distinct(USUBJID)) + CHGCAT1, + ANL03FL + ) + +# restrict to these - ordered by PARAMN +selparamcd <- as.character( + adeg |> arrange(PARAMN) |> pull(PARAMCD) |> unique() +) + +adeg <- adeg |> + mutate( + PARAMCD := factor(PARAMCD, levels = selparamcd), + PARAM := factor(PARAM) + ) |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) colspan_trt_map <- create_colspan_map( adsl, @@ -138,8 +132,6 @@ colspan_trt_map <- create_colspan_map( trt_var = trtvar ) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - ################################################################################ # Define layout and build table: ################################################################################ @@ -150,48 +142,64 @@ extra_args_rr <- list( ) -lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by( - trtvar - # , split_fun = add_combo_levels(combodf) - ) %>% - ### if risk diff columns are wanted - re-enable next 2 split_cols_by lines - # split_cols_by("rrisk_header", nested = FALSE) %>% - # split_cols_by(trtvar, labels_var = "rrisk_label", - # split_fun = remove_split_levels(ctrl_grp)) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +lyt <- lyt |> split_rows_by( - "PARAM", + "PARAMCD", + labels_var = "PARAM", split_label = "QTc Interval", label_pos = "topleft", split_fun = drop_split_levels, section_div = " " - ) %>% + ) |> analyze( c("CHGCAT1"), a_freq_j, extra_args = extra_args_rr, show_labels = "hidden", - indent_mod = 1L - ) %>% - append_topleft(" Criteria, n (%)") + indent_mod = 0L + ) |> + append_topleft(" Criteria, n (%)") + +result <- build_table(lyt, adeg, alt_counts_df = adsl, round_type = "sas") -result <- build_table(lyt, adeg, alt_counts_df = adsl) + +################################################################################ +# Post-Processing: +# - remove unwanted colcounts +# - adjust Combined column N if combined_colspan_trt = TRUE +################################################################################ + +result <- remove_col_count(result) ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(54, 21, 21, 21) + +colwidth <- c(51, 21, 21, 21, 21) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfecg04.R b/tests/testthat/source_code/tsfecg04.R index 5474c489..85457df7 100644 --- a/tests/testthat/source_code/tsfecg04.R +++ b/tests/testthat/source_code/tsfecg04.R @@ -1,32 +1,9 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfecg04 -## R version: 4.2.1 -## Short Description: Program to create tsfecg04: Shift From Baseline to -## Maximum On-treatment Corrected QT Interval -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adeg.RDS -## Output: tsfecg04.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(haven) library(rlang) ################################################################################ @@ -35,7 +12,7 @@ library(rlang) tblid <- "TSFECG04" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" @@ -44,81 +21,94 @@ titles <- list( popfl <- "SAFFL" trtvar <- "TRT01A" ctrl_grp <- "Placebo" -demogvars <- c("SEX", "AGEGR1", "RACE", "ETHNIC", "AGE") - -ad_domain <- "ADEG" ## selection of QTC parameters -selparamcd <- c("QTCFAG", "QTCBAG", "QTCS", "QTCLAG") +selparamcd <- c("QTCBAG", "QTCFAG", "QTCS", "QTCLAG") ################################################################################ # initial read of data ################################################################################ -adeg_complete <- adeg_jnj - -### available QTC parameters in study -selparamcd <- intersect(selparamcd, unique(adeg_complete$PARAMCD)) - -catvar <- "AVALCAT1" ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(c(trtvar, popfl, demogvars))) - -adsl <- adsl %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + select(STUDYID, USUBJID, all_of(c(trtvar, popfl))) |> mutate( - colspan_trt = factor( - ifelse(!!sym(trtvar) == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar ) -## to ensure the same order as on other outputs -trt_order <- as.character((unique( - adsl %>% select("colspan_trt", all_of(trtvar)) -) %>% - arrange(colspan_trt, !!sym(trtvar)))[[trtvar]]) -adsl[[trtvar]] <- factor(as.character(adsl[[trtvar]]), levels = trt_order) - -adeg <- adeg_complete %>% - filter(PARAMCD %in% selparamcd) %>% + +adeg_complete <- adeg_jnj + +### available QTC parameters in study +selparamcd <- intersect(selparamcd, unique(adeg_complete$PARAMCD)) + + +adeg <- adeg_complete |> + filter(!is.na(USUBJID), .data[[popfl]] == "Y", !is.na(.data[[trtvar]]), PARAMCD %in% selparamcd, ANL03FL == "Y") |> ### Maximum On-treatment ### note: by filter ANL03FL, this table is restricted to On-treatment values, per definition of ANL03FL ### therefor, no need to add ONTRTFL in filter ### if derivation of ANL03FL is not restricted to ONTRTFL records, adding ONTRTFL here will not give the correct answer either ### as mixing worst with other period is not giving the proper selection !!! - filter(ANL03FL == "Y") %>% select( + STUDYID, USUBJID, - ONTRTFL, - TRTEMFL, PARAM, + PARAMN, PARAMCD, - AVISITN, AVISIT, AVAL, BASE, - CHG, AVALCAT1, BASECAT1, ONTRTFL, - TRTEMFL, - ANL01FL, - ANL02FL, - ANL03FL - ) %>% - inner_join(., adsl) + ANL03FL, + all_of(trtvar) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) -adeg$AVISIT <- factor("Maximum Corrected QT Interval") +# restrict to these - ordered by PARAMN +selparamcd <- as.character( + adeg |> arrange(PARAMN) |> pull(PARAMCD) |> unique() +) + +adeg <- adeg |> + mutate( + PARAMCD := factor(PARAMCD, levels = selparamcd), + PARAM := factor(PARAM), + AVISIT = factor("Maximum corrected QT interval, n", levels = c("Maximum corrected QT interval, n")) + ) |> + inner_join(adsl, by = c("STUDYID", "USUBJID", trtvar)) -## if also over time is needed, append these to above dataset -## see ecg05 as example -check1 <- adeg %>% - group_by(TRT01A, PARAMCD, AVISIT) %>% +check1 <- adeg |> + group_by(TRT01A, PARAMCD, AVISIT) |> summarize(n = n_distinct(USUBJID)) @@ -133,7 +123,7 @@ AVALCAT1_levels <- levels(adeg$AVALCAT1) ## add extra level N to Basecat1 -adeg <- adeg %>% +adeg <- adeg |> mutate( BASECAT1 = factor(as.character(BASECAT1), levels = c("N", AVALCAT1_levels)) ) @@ -141,8 +131,8 @@ adeg <- adeg %>% ## trick for alt_counts_df to work with col splitting # add BASECAT1 to adsl, all assign to extra level N (column will be used for N counts) -adslx <- adsl %>% - mutate(BASECAT1 = "N") %>% +adslx <- adsl |> + mutate(BASECAT1 = "N") |> mutate(BASECAT1 = factor(BASECAT1, levels = c("N", AVALCAT1_levels))) @@ -150,18 +140,19 @@ adslx$BASECAT1_header <- "Baseline Corrected QT Interval" adslx$BASECAT1_header2 <- " " adslx$BASECAT1_header3 <- " " ## extra to allow for additional topleft material + ################################################################################ # Define layout and build table: ################################################################################ -lyt <- basic_table(show_colcounts = FALSE) %>% - split_cols_by("BASECAT1_header3") %>% +lyt <- basic_table(show_colcounts = FALSE) |> + split_cols_by("BASECAT1_header3") |> ## to ensure N column is not under the Baseline column span header - split_cols_by("BASECAT1_header2") %>% - split_cols_by("BASECAT1", split_fun = keep_split_levels("N")) %>% + split_cols_by("BASECAT1_header2") |> + split_cols_by("BASECAT1", split_fun = keep_split_levels("N")) |> ## restart column split (Nested = False) ## Combined levels will be made, and the N column should not appear - split_cols_by("BASECAT1_header", nested = FALSE) %>% + split_cols_by("BASECAT1_header", nested = FALSE) |> split_cols_by( "BASECAT1", split_fun = make_split_fun( @@ -170,7 +161,7 @@ lyt <- basic_table(show_colcounts = FALSE) %>% add_overall_facet("TOTAL", "Total") ) ) - ) %>% + ) |> #### replace split_rows and summarize by single analyze call ### a_freq_j only works due to ### special arguments can do the trick : denomf = adslx & .stats = count_unique @@ -185,25 +176,26 @@ lyt <- basic_table(show_colcounts = FALSE) %>% extrablankline = TRUE ), indent_mod = -1L - ) %>% + ) |> # ## main part of table split_rows_by( - "PARAM", + "PARAMCD", + labels_var = "PARAM", nested = FALSE, label_pos = "topleft", child_labels = "visible", split_label = "QTc Interval", split_fun = drop_split_levels, section_div = " " - ) %>% + ) |> split_rows_by( trtvar, label_pos = "topleft", - indent_mod = -1L, + indent_mod = 0L, child_labels = "hidden", split_label = "Treatment Group", section_div = " " - ) %>% + ) |> ### a_freq_j ### the special statistic "n_rowdf" option does the trick here of getting the proper value for the N column summarize_row_groups( @@ -212,16 +204,17 @@ lyt <- basic_table(show_colcounts = FALSE) %>% extra_args = list( .stats = "n_rowdf", restr_columns = c("N") - ) - ) %>% + ), + indent_mod = 0L + ) |> split_rows_by( "AVISIT", label_pos = "hidden", - indent_mod = 1L, + indent_mod = 0L, split_label = " ", child_labels = "visible", section_div = " " - ) %>% + ) |> ## add extra level TOTAL using new_levels, rather than earlier technique ## advantage for denominator derivation -- n_rowdf can be used, if we'd like to present fraction as well ## switch .stats to count_unique_denom_fraction or count_unique_fraction @@ -233,23 +226,21 @@ lyt <- basic_table(show_colcounts = FALSE) %>% denom = "n_rowdf", new_levels = list(c("Total"), list(AVALCAT1_levels)), new_levels_after = TRUE, - .indent_mods = 1L, + .indent_mods = 0L, restr_columns = c( toupper(AVALCAT1_levels), "TOTAL" ) ) - ) %>% - append_topleft(" Criteria, n") + ) -result <- build_table(lyt, adeg, alt_counts_df = adslx) -# head(result, 20) +result <- build_table(lyt, adeg, alt_counts_df = adslx, round_type = "sas") ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table @@ -272,6 +263,7 @@ colwidths <- def_colwidths( acolwidths <- colwidths acolwidths[3:length(acolwidths)] <- 12 -acolwidths <- c(58, 11, 12, 12, 12, 12, 12) -tt_to_tlgrtf(result, file = fileid, colwidths = acolwidths) +colwidth <- c(60, 7, 7, 5, 5, 5, 7) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfecg05.R b/tests/testthat/source_code/tsfecg05.R index 211eb40e..b74baf23 100644 --- a/tests/testthat/source_code/tsfecg05.R +++ b/tests/testthat/source_code/tsfecg05.R @@ -1,34 +1,9 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfecg05 -## R version: 4.2.1 -## Short Description: Program to create tsfecg05: Subjects With ECG Values -## Outside Specified Limits Based on -## On-treatment Value and Over Time -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adeg.RDS -## Output: tsfecg05.rtf -## Remarks: carefully review factor levels of variables CRIT1/CRIT2 on your input adeg.rds dataset -## check consistency in order CRIT1 and CRIT2 : here: CRIT2 (low), CRIT1 (high) -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(haven) ################################################################################ # Define script level parameters: @@ -36,7 +11,7 @@ library(junco) tblid <- "TSFECG05" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" @@ -46,7 +21,12 @@ popfl <- "SAFFL" trtvar <- "TRT01A" ctrl_grp <- "Placebo" -ad_domain <- "adeg" +## if the option TRTEMFL needs to be added to the TLF +trtemfl <- TRUE + +# flag to indclude timepoint rows +over_time <- TRUE + selvisit <- c( "Month 1", @@ -59,38 +39,82 @@ selvisit <- c( "Month 24" ) -selvisit <- c("Month 1", "Month 3") -catvar <- c("CRIT1", "CRIT2") +# Add Active Study Agent Combined column? +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + ################################################################################ # initial read of data ################################################################################ +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + select(STUDYID, USUBJID, all_of(c(trtvar, popfl))) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) + + adeg_complete <- adeg_jnj ## check parameters that have CRIT1,CRIT2 defined in data -levels_data <- unique(adeg_complete %>% select(PARAMCD, PARAM, CRIT1, CRIT2)) - -# restrict to these -selparamcd <- as.character(unique( - levels_data %>% filter(!(is.na(CRIT1) | is.na(CRIT2))) %>% pull(PARAMCD) -)) +levels_data <- unique(adeg_complete |> select(PARAMCD, PARAM, PARAMN, CRIT1, CRIT2)) + +# restrict to these - ordered by PARAMN +selparamcd <- as.character( + levels_data |> + filter(!(is.na(CRIT1) | is.na(CRIT2))) |> + arrange(PARAMN) |> + pull(PARAMCD) |> + unique() +) -## if the option TRTEMFL needs to be added to the TLF -trtemfl <- TRUE ################################################################################ # Mapping for CRIT1/2 ################################################################################ -xlabel_map <- levels_data %>% +xlabel_map <- levels_data |> tidyr::pivot_longer( cols = c("CRIT1", "CRIT2"), names_to = "var", values_to = "label" - ) %>% - filter(!is.na(label)) %>% + ) |> + filter(!is.na(label)) |> mutate( label = as.character(label), var = paste0(var, "FL"), @@ -101,26 +125,23 @@ xlabel_map <- levels_data %>% ## for both EGHRMN & PRAG: crit1 and crit2 are reversed ## crit1 and crit2 on data are consistent with the order specified in the shell : low/high -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select(USUBJID, all_of(c(trtvar, popfl))) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -adsl$rrisk_header <- "Risk Difference (%) (95% CI)" -adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) - - -adeg <- adeg_complete %>% - filter(PARAMCD %in% selparamcd) %>% +adeg <- adeg_complete |> + filter( + !is.na(USUBJID), + .data[[popfl]] == "Y", + !is.na(.data[[trtvar]]), + PARAMCD %in% selparamcd + ) |> + mutate( + CRIT1FL = ifelse(!is.na(CRIT1FL) & CRIT1FL == "Y", "Y", "N"), + CRIT2FL = ifelse(!is.na(CRIT2FL) & CRIT2FL == "Y", "Y", "N"), + PARAMCD := factor(PARAMCD, levels = selparamcd), + PARAM := factor(PARAM), + # Baseline records: label AVISIT as "Baseline" using ABLFL flag + AVISIT := factor(as.character(AVISIT), levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))]) + ) |> select( + STUDYID, USUBJID, PARAM, PARAMCD, @@ -132,11 +153,11 @@ adeg <- adeg_complete %>% CRIT2FL, starts_with("ANL") & ends_with("FL"), ONTRTFL, - TRTEMFL, - APOBLFL - ) %>% - inner_join(., adsl) + TRTEMFL + ) |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) +selvisit <- unique(as.character(adeg$AVISIT[adeg$AVISIT %in% selvisit])) ################################################################################ ##### filter data @@ -145,10 +166,10 @@ adeg <- adeg_complete %>% ### alert on trtemfl, do not apply it as a filter, as this would lead to incorrect denominators adeg_crit_any <- unique( - adeg %>% + adeg |> # synthetic data is missing the ANL04FL variable, however, this wouldn't be sufficient either, unless it flags both CRIT1 and CRIT2 - filter(ONTRTFL == "Y") %>% - mutate(AVISIT = factor("On-treatment")) %>% + filter(ONTRTFL == "Y") |> + mutate(AVISIT = factor("On-treatment")) |> select(-c(AVAL, ANL01FL, ANL02FL, ANL03FL)) ) @@ -157,30 +178,37 @@ adeg_crit_any <- unique( ### a subject can have crit1fl=Y at one visit, and crit2fl=Y at another visit, and crit1fl=N&crit2fl=N at another ### as long as the analysis function deals with multiple records per subject correctly, this is not an issue -check_dup_sub <- adeg_crit_any %>% - group_by(USUBJID, PARAMCD, AVISIT) %>% - mutate(n_rec = n()) %>% +check_dup_sub <- adeg_crit_any |> + group_by(USUBJID, PARAMCD, AVISIT) |> + mutate(n_rec = n()) |> filter(n_rec > 1) # Over time is also restricted to on treatment value -adeg_crit_overtime <- adeg %>% - filter(ANL02FL == "Y" & AVISIT %in% selvisit & ONTRTFL == "Y") %>% - select(-c(AVAL, ANL01FL, ANL02FL, ANL03FL)) +if (over_time) { + adeg_crit_overtime <- adeg |> + filter(ANL02FL == "Y" & AVISIT %in% selvisit & ONTRTFL == "Y") |> + select(-c(AVAL, ANL01FL, ANL02FL, ANL03FL)) |> + mutate(AVISIT = factor(as.character(AVISIT), levels = selvisit)) -adeg_crit_comb <- rbind(adeg_crit_any, adeg_crit_overtime) %>% - mutate( - AVISIT = factor( - as.character(AVISIT), - levels = c("On-treatment", levels(adeg_crit_overtime$AVISIT)) - ) - ) %>% - inner_join(., adsl) + adeg_crit_comb <- rbind(adeg_crit_any, adeg_crit_overtime) |> + mutate( + AVISIT = factor( + as.character(AVISIT), + levels = c("On-treatment", levels(adeg_crit_overtime$AVISIT)) + ) + ) |> + inner_join(adsl) +} else { + adeg_crit_comb <- adeg_crit_any |> + mutate(AVISIT = factor(as.character(AVISIT), levels = "On-treatment")) |> + inner_join(adsl) +} #### DO NOT USE TRTEMFL = Y in filter, as this will remove subjects from both numerator and denominator #### instead : set "CRIT2FL","CRIT1FL" to a non-reportable value (ie N) and keep in dataset if (trtemfl) { - adeg_crit_comb <- adeg_crit_comb %>% + adeg_crit_comb <- adeg_crit_comb |> mutate( CRIT1FL = case_when( is.na(TRTEMFL) | TRTEMFL != "Y" ~ "N", @@ -193,7 +221,7 @@ if (trtemfl) { ) } -adeg_crit_comb <- adeg_crit_comb %>% +adeg_crit_comb <- adeg_crit_comb |> mutate( CRIT1FL = factor(CRIT1FL, levels = c("Y", "N")), CRIT2FL = factor(CRIT2FL, levels = c("Y", "N")) @@ -219,40 +247,42 @@ extra_args_rr2 <- list( .stats = c("count_unique_fraction") ) -lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% +lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by( - trtvar - # , split_fun = add_combo_levels(combodf) - ) %>% - # re-enable the below if relative risk columns are wanted - # split_cols_by("rrisk_header", nested = FALSE) %>% - # split_cols_by(trtvar, labels_var = "rrisk_label", - # split_fun = remove_split_levels(ctrl_grp)) %>% - # + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +lyt <- lyt |> split_rows_by( - "PARAM", + "PARAMCD", + labels_var = "PARAM", split_label = "Parameter", label_pos = "topleft", split_fun = drop_split_levels - ) %>% + ) |> split_rows_by( "AVISIT", split_label = "Study Visit", label_pos = "topleft", section_div = " ", split_fun = drop_split_levels - ) %>% + ) |> analyze( c("CRIT1"), a_freq_j, extra_args = extra_args_rr1, show_labels = "hidden", indent_mod = 0L - ) %>% + ) |> # denominators are varying per test, no need to show as N is shown in line above # revise order to first present low then high analyze( @@ -267,22 +297,23 @@ lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% ), show_labels = "hidden", indent_mod = 1L - ) %>% + ) |> append_topleft(" Criteria, n (%)") -result <- build_table(lyt, adeg_crit_comb, alt_counts_df = adsl) +result <- build_table(lyt, adeg_crit_comb, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(56, 23, 23, 23) + +colwidth <- c(56, 21, 23, 23, 21) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfecg06.R b/tests/testthat/source_code/tsfecg06.R new file mode 100644 index 00000000..603d8708 --- /dev/null +++ b/tests/testthat/source_code/tsfecg06.R @@ -0,0 +1,264 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) +library(haven) + +################################################################################ +# Define script level parameters: +################################################################################ + +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Define control group label +# - PARAMCD=INTP: ECG Overall Interpretation parameter +# - AVALC categories: Abnormal, CS / Abnormal, NCS / Normal +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +# - Records selected: ANL02FL="Y" and (ABLFL="Y" or APOBLFL="Y") +################################################################################ + +tblid <- "TSFECG06" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "SAFFL" +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" + +# Add Active Study Agent Combined column? +combined_colspan_trt <- TRUE + +# ECG Overall Interpretation parameter +selparamcd <- "INTP" + +# AVALC levels for ECG interpretation (order as shown in mock) +avalc_levels <- c("Abnormal, CS", "Abnormal, NCS", "Normal") + +# All visits of interest (Baseline + post-baseline timepoints) +selvisit <- c( + "Baseline", + "Month 1", + "Month 3", + "Month 6", + "Month 9", + "Month 12", + "Month 15", + "Month 18", + "Month 24" +) + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +################################################################################ +# Process Data: +################################################################################ + +adsl <- adsl_jnj |> + select(STUDYID, USUBJID, all_of(c(popfl, trtvar))) |> + filter( + toupper(.data[[popfl]]) == "Y", + !is.na(.data[[trtvar]]) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) + +adeg <- adeg_jnj + +### available Interpretation parameters in study +selparamcd <- intersect(selparamcd, unique(adeg$PARAMCD)) + +adeg <- adeg |> + select( + STUDYID, + USUBJID, + all_of(c(popfl, trtvar)), + AVISITN, + AVISIT, + PARAMCD, + PARAM, + PARAMN, + AVALC, + starts_with("ANL"), + ABLFL, + APOBLFL + ) |> + filter( + !is.na(USUBJID), + .data[[popfl]] == "Y", + !is.na(.data[[trtvar]]), + PARAMCD %in% selparamcd, + AVISIT %in% selvisit + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + +selparamcd <- as.character( + adeg |> arrange(PARAMN) |> pull(PARAMCD) |> unique() +) + +adeg <- adeg |> + mutate( + ABLFL := factor(ifelse(!is.na(ABLFL) & ABLFL == "Y", "Y", "N")), + APOBLFL := factor(ifelse(!is.na(APOBLFL) & APOBLFL == "Y", "Y", "N")), + PARAMCD := factor(PARAMCD, levels = selparamcd), + PARAM := factor(PARAM), + # Baseline records: label AVISIT as "Baseline" using ABLFL flag + AVISIT = factor( + ifelse(ABLFL == "Y" & !is.na(ABLFL), "Baseline", as.character(AVISIT)), + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ), + # Apply ordered levels to AVALC for consistent display + AVALC := factor( + dplyr::case_when( + toupper(AVALC) == "ABNORMAL, CS" ~ "Abnormal, CS", + toupper(AVALC) == "ABNORMAL, NCS" ~ "Abnormal, NCS", + toupper(AVALC) == "NORMAL" ~ "Normal", + TRUE ~ NA_character_ + ), + levels = avalc_levels + ) + ) + +selvisit <- unique(as.character(adeg$AVISIT[adeg$AVISIT %in% selvisit])) + +adeg <- inner_join(adsl, adeg, by = c("STUDYID", "USUBJID", popfl, trtvar)) + +# Filter to records of interest: Baseline (ABLFL=Y) and post-baseline (APOBLFL=Y), +# both requiring ANL02FL=Y, restricted to selected visits +adeg <- adeg |> + filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) |> + filter(AVISIT %in% selvisit) |> + mutate( + AVISIT = factor(as.character(AVISIT), levels = selvisit) + ) + +################################################################################ +# Define layout and build table: +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + + +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx", + top_level_section_div = " " +) |> + append_topleft("Study Visit") |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +lyt <- lyt |> + # ── Visit split: Baseline + post-baseline timepoints ──────────────────────── + split_rows_by( + "AVISIT", + split_fun = keep_split_levels(selvisit), + label_pos = "topleft", + split_label = " Overall Interpretation, n (%)", + section_div = " " + ) |> + # N count per visit (subjects with a record at this timepoint) + analyze( + "AVALC", + afun = a_freq_j, + extra_args = list( + .stats = "n_df", + denom = "N_col" + ), + show_labels = "hidden", + indent_mod = 0L + ) |> + # AVALC category counts: Abnormal CS, Abnormal NCS, Normal — n (%) + analyze( + "AVALC", + afun = a_freq_j, + extra_args = list( + .stats = "count_unique_fraction", + denom = "n_df" + ), + table_names = "avalc_freq", + show_labels = "hidden", + indent_mod = 1L + ) + +result <- build_table(lyt, adeg, alt_counts_df = adsl, round_type = "sas") + + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(30, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab01.R b/tests/testthat/source_code/tsflab01.R deleted file mode 100644 index 3f258854..00000000 --- a/tests/testthat/source_code/tsflab01.R +++ /dev/null @@ -1,605 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab01 -## R version: 4.2.1 -## Short Description: Program to create tsflab01: Mean Change From Baseline -## for [Laboratory Category] Laboratory Data Over Time -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab01.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFLAB01" -titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) -fileid <- write_path(opath, tblid) - -popfl <- "SAFFL" -trtvar <- "TRT01A" -ctrl_grp <- "Placebo" - - -# Note on ancova parameter -# when ancova = TRUE -# ancova model will be used to calculate all mean/mean change columns -# not just those from the Difference column -# model specification -summ_vars <- list(arm = trtvar, covariates = NULL) - -# when ancova = FALSE, all mean/mean change columns will be from descriptive stats -# for the difference column descriptive stats will be based upon two-sample t-test -ancova <- FALSE - - -comp_btw_group <- TRUE - - -## For analysis on SI units: use adlb dataset -## For analysis on Conventional units: use adlbc dataset -- shell is in conventional units - -ad_domain <- "ADLB" - -# see further, an alternative method to identify all non-unscheduled visits based upon data -selvisit <- c("Screening", "Baseline", "Cycle 02", "Cycle 03", "Cycle 04") - - -### note : this shell covers multiple tables depending on parcat3 selections - -## allowed PARCAT3 selections - -# parcat3sel <- "General chemistry" -# parcat3sel <- "Kidney function" -# parcat3sel <- "Liver biochemistry" -# parcat3sel <- "Lipids" -# -# ### Hematology (HM) : has 3 subcategories that should be included on one table -# parcat3sel <- c("Complete blood count","WBC differential","Coagulation studies") - -# per DPS specifications, the output identifier should include the abbreviation for the category - -# 1. Present laboratory tests using separate outputs for each category as follows: -# General chemistry (GC): Sodium, Potassium, Chloride, Bicarbonate, Urea Nitrogen, Glucose, Calcium, Magnesium, Phosphate, Protein, Albumin, Creatine Kinase, Amylase, Lipase -# Kidney function (KF): Creatinine, GFR from Creatinine -# Liver biochemistry (LV): Alkaline Phosphatase, Alanine Aminotransferase, Aspartate Aminotransferase, Bilirubin, Prothrombin Intl. Normalized Ratio, Gamma Glutamyl Transferase -# Lipids (LP): Cholesterol, HDL Cholesterol, LDL Cholesterol, Triglycerides -# Hematology (HM): Subcategory rows should be included for Complete Blood Count, White Blood Cell Differential and for Coagulation Studies -# Complete blood count: Leukocytes, Hemoglobin, Platelets; -# WBC differential: Lymphocytes, Neutrophils, Eosinophils; -# Coagulation studies: Prothrombin Time, Activated Partial Thromboplastin Time. - -# The output identifier should include the abbreviation for the laboratory category (eg, TSFLAB02GC for General Chemistry) - -# In current template program, only 1 version is created, without the proper abbreviation appended -# The reason for this is that TSFLAB02GC is not included in the DPS system - only the core version TSFLAB02 - -get_abbreviation <- function(parcat3sel) { - parcat3sel <- toupper(parcat3sel) - abbr <- NULL - if (length(parcat3sel) == 1) { - if (parcat3sel == toupper("General chemistry")) { - abbr <- "GC" - } - # the following line should be removed for a true study, global jjcs standards in DPS system does not include the abbreviation - if (parcat3sel == toupper("General chemistry")) { - abbr <- "" - } - # - if (parcat3sel == toupper("Kidney function")) { - abbr <- "KF" - } - if (parcat3sel == toupper("Liver biochemistry")) { - abbr <- "LV" - } - if (parcat3sel == toupper("Lipids")) abbr <- "LP" - } - if (length(parcat3sel) > 1) { - if ( - all( - parcat3sel %in% - toupper(c( - "Complete blood count", - "WBC differential", - "Coagulation studies" - )) - ) - ) { - abbr <- "HM" - } - } - - if (is.null(abbr)) { - message("Incorrect specification of parcat3sel") - } - - abbr -} - -get_tblid <- function(tblid, parcat3sel, method = c("after", "inbetween")) { - abbr <- get_abbreviation(parcat3sel) - - method <- match.arg(method) - # when inbetween, the abbreviation will be added prior to the number part of the table identifier - # when after (default), the abbreviation will be added at the end of the table identifier - - x <- 0 - if (method == "inbetween") { - x <- regexpr(pattern = "[0-9]", tblid)[1] - } - - if (x > 0) { - tblid1 <- substr(tblid, 1, x - 1) - tblid2 <- substring(tblid, x) - tblid_new <- paste0(tblid1, abbr, tblid2) - } else { - tblid_new <- paste0(tblid, abbr) - } - - return(tblid_new) -} - -## parcat3 options : -# current data: Liver biochemistry, General chemistry, Lipids, Kidney function, Complete blood count, WBC differential -# according shell: General chemistry, Kidney function, Liver biochemistry, Lipids, Hematology - -## not in shell: Complete blood count, WBC differential -## not in data: Hematology - -availparcat3 <- c( - "General chemistry", - "Kidney function", - "Liver biochemistry", - "Lipids", - "Complete blood count", - "WBC differential", - "" -) - - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select( - STUDYID, - USUBJID, - all_of(c(popfl, trtvar)), - SEX, - AGEGR1, - RACE, - ETHNIC, - AGE - ) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -adsl$rrisk_header <- "Difference in Mean Change (95% CI)" -adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) - - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - -adlb_complete <- adlb_jnj - -# selection of all non-unscheduled visits from data -visits <- adlb_complete %>% - select(AVISIT) %>% - filter(!grepl("UNSCHEDULED", toupper(AVISIT))) - -visits$AVISIT <- droplevels(visits$AVISIT) -selvisit_data <- levels(visits$AVISIT) - -### if preferred to get it from data, rather than hardcoded list of visits -# selvisit <- selvisit_data - -adlb00 <- adlb_complete %>% - select( - USUBJID, - AVISITN, - AVISIT, - starts_with("PAR"), - AVAL, - BASE, - CHG, - PCHG, - starts_with("ANL"), - ABLFL, - APOBLFL - ) %>% - inner_join(adsl) %>% - relocate(USUBJID, PARAMCD, AVISIT, ANL02FL, ABLFL, APOBLFL) - -parcat <- unique(adlb00 %>% select(starts_with("PARCAT"), PARAMCD, PARAM)) - -## retrieve the precision of AVAL on the input dataset -## review outcome and make updates manually if needed -## the precision variable will be used for the parameter-based formats in layout - -## decimal = 4 is a cap in this derivation: if decimal precision of variable > decimal, the result will end up as decimal -## eg if AVAL has precision of 6 for parameter x, and decimal = 4, the resulting decimal value for parameter x is 4 - -## note that precision is on the raw values, as we are presenting mean/ci, and extra digit will be added -## eg precision = 2 will result in mean/ci format xx.xxx (xx.xxx, xx.xxx) - -lb_precision <- tidytlg:::make_precision_data( - df = adlb00, - decimal = 3, - precisionby = "PARAMCD", - precisionon = "AVAL" -) - -### data preparation - -filtered_adlb <- adlb00 %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) - -#### perform check on unique record per subject/param/timepoint -check_unique <- filtered_adlb %>% - group_by(USUBJID, PARAMCD, AVISIT) %>% - mutate(n_recsub = n()) %>% - filter(n_recsub > 1) - -if (nrow(check_unique) > 0) { - stop( - "Your input dataset needs extra attention, as some subjects have more than one record per parameter/visit" - ) - ### you will run into issues with fraction portion in count_denom_fraction, as count > denom, and fraction > 1 if you don't adjust your input dataset - - # Possible extra derivation - just to ensure program can run without issues - ### Study team is responsible for adding this derivation onto ADaM dataset and ensure proper derivation rule for ANL02FL is implemented !!!!!!!!!! - filtered_adlbx <- adlb00 %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) %>% - group_by(USUBJID, PARAM, AVISIT) %>% - mutate(n_sub = n()) %>% - arrange(USUBJID, PARAM, AVISIT, ADT) %>% - mutate(i = vctrs::vec_group_id(ADT)) %>% - mutate( - ANL02FL = case_when( - n_sub == 1 ~ "Y", - i == 1 ~ "Y" - ) - ) %>% - select(-c(i, n_sub)) %>% - ungroup() - - filtered_adlb <- filtered_adlbx %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) - - ## now your data should contain 1 record per subject per parameter -} - - -### for denominator per timepoint: all records from adlb on this timepoint: ignoring anl01fl/anl02fl/param -filtered_adlb_timepoints <- unique( - adlb00 %>% - filter(AVISIT %in% selvisit) %>% - select(USUBJID, AVISITN, AVISIT) -) %>% - inner_join(adsl) - -################################################################################ -# Define layout and build table: -################################################################################ - -################################################################################ -# Core function to produce shell for specific parcat3 selection -################################################################################ - -build_result_parcat3 <- function( - df = filtered_adlb, - df_timepoints = filtered_adlb_timepoints, - df_orig = adlb00, - PARCAT3sel = NULL, - .adsl = adsl, - tblid, - save2rtf = TRUE, - .summ_vars = summ_vars, - .trtvar = trtvar, - .ref_path = ref_path -) { - tblidx <- get_tblid(tblid, PARCAT3sel) - titles2 <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" - ) - - .ctrl_grp <- utils::tail(.ref_path, n = 1) - - multivars <- c("AVAL", "AVAL", "CHG") - extra_args_3col <- list( - format_na_str = rep("NA", 3), - d = "decimal", - variables = .summ_vars, - ancova = ancova, - comp_btw_group = comp_btw_group, - ref_path = .ref_path, - multivars = multivars - ) - - if (!is.null(PARCAT3sel)) { - df <- df %>% - filter(PARCAT3 %in% PARCAT3sel) - } - - ### continue with data preparation - params <- unique(df %>% select(PARAMCD, PARAM)) - - df_timepoints <- df_timepoints %>% - mutate(dummy_join = 1) %>% - full_join( - params %>% mutate(dummy_join = 1), - relationship = "many-to-many" - ) %>% - select(-dummy_join) - - ### identify subjects in df_timepoints and not in df - - extra_sub <- anti_join(df_timepoints, df) - - ### only add these extra_sub to - ### this will ensure we still meet the one record per subject per timepoint - ### this will ensure length(x) can be used for the denominator derivation inside summarize_aval_chg_diff function - - df <- bind_rows(df, extra_sub) %>% - arrange(USUBJID, PARAM, AVISITN) - - df <- df %>% - inner_join(lb_precision, by = "PARAMCD") - - ### important: previous actions lost the label of variables - ### in order to be able to use obj_label(filtered_adlb$PARAM) in layout, need to redefine the label - df <- var_relabel_list(df, var_labels(df_orig, fill = T)) - - ################################################################################ - # Define layout and build table: - ################################################################################ - - lyt <- basic_table(show_colcounts = FALSE, colcount_format = "N=xx") %>% - ### first columns - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(.trtvar, show_colcounts = TRUE, colcount_format = "N=xx") %>% - split_rows_by( - "PARAM", - label_pos = "topleft", - split_label = "Laboratory Test", - section_div = " ", - split_fun = drop_split_levels - ) %>% - ## note the child_labels = hidden for AVISIT, these labels will be taken care off by - ## applying function summarize_aval_chg_diff further in the layout - split_rows_by( - "AVISIT", - label_pos = "topleft", - split_label = "Study Visit", - split_fun = drop_split_levels, - child_labels = "hidden" - ) %>% - ## set up a 3 column split - split_cols_by_multivar( - multivars, - varlabels = c( - "n/N (%)", - "Mean (95% CI)", - "Mean Change From Baseline (95% CI)" - ) - ) %>% - ### restart for the rrisk_header columns - note the nested = FALSE option - ### also note the child_labels = "hidden" in both PARAM and AVISIT - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - .trtvar, - split_fun = remove_split_levels(.ctrl_grp), - labels_var = "rrisk_label", - show_colcounts = TRUE, - colcount_format = "N=xx" - ) %>% - ### difference columns : just 1 column & analysis needs to be done on change - split_cols_by_multivar(multivars[3], varlabels = c(" ")) %>% - ### the variable passed here in analyze is not used (STUDYID), it is a dummy var passing, - ### the function summarize_aval_chg_diff grabs the required vars from cols_by_multivar calls - analyze( - "STUDYID", - afun = a_summarize_aval_chg_diff_j, - extra_args = extra_args_3col - ) - - if (nrow(df) > 0) { - result <- build_table(lyt, df, alt_counts_df = .adsl) - - ################################################################################ - # Post-Processing: - # - Prune table to remove when n = 0 in all columns - # - Remove the N=xx column headers for the difference vs PBO columns - ################################################################################ - - ### alhtough this is not really likely to occur in real data, this is a problem in the current synthetic data - ### also here, try to remove this issue - - # rps_result <- row_paths_summary(result) - - ### below code is based upon tern pruning function has_count_in_any_col, with updates to internal function h_row_first_values for the 3 column - format we are using here - - my_has_count_in_any_col <- function(atleast, ...) { - checkmate::assert_count(atleast) - CombinationFunction(function(table_row) { - row_counts <- my_h_row_counts(table_row, ...) - ### small update compared to tern::has_count_in_any_col - ## > vs >= - any(row_counts > atleast) - }) - } - - my_h_row_counts <- - function(table_row, col_names = NULL, col_indices = NULL) { - ## no updates compared to tern::h_row_counts, beyond using the customized my_h_row_first_values function - counts <- my_h_row_first_values(table_row, col_names, col_indices) - checkmate::assert_integerish(counts) - counts - } - - my_h_row_first_values <- function(table_row, - col_names = NULL, - col_indices = NULL) { - col_indices <- tern:::check_names_indices( - table_row, - col_names, - col_indices - ) - checkmate::assert_integerish(col_indices) - checkmate::assert_subset(col_indices, seq_len(ncol(table_row))) - - # Main values are extracted - row_vals <- row_values(table_row)[col_indices] - - ### specific updates to current situation -- 3 column layout, I want to grab the information from the n/N column, which is in first analysis of AVAL - specific_cols <- names(row_vals) - specific_cols <- specific_cols[stringr::str_ends(specific_cols, "AVAL")] - - row_vals <- row_vals[specific_cols] - - # Main return - vapply( - row_vals, - function(rv) { - if (is.null(rv)) { - NA_real_ - } else { - rv[1L] - } - }, - FUN.VALUE = numeric(1) - ) - } - - more_than_0 <- my_has_count_in_any_col(atleast = 0) - - ## seem to work ok, not clear why it goes through each row twice? - result <- prune_table(result, keep_rows(more_than_0)) - - ## Remove the N=xx column headers for the difference vs PBO columns - remove_col_count2 <- function(result, string = paste("vs", ctrl_grp)) { - mcdf <- make_col_df(result, visible_only = FALSE) - mcdfsel <- mcdf %>% - filter(stringr::str_detect(toupper(label), toupper(string))) %>% - pull(path) - - for (i in seq_along(mcdfsel)) { - facet_colcount(result, mcdfsel[[i]]) <- NA - } - - return(result) - } - - result <- remove_col_count2(result) - } else { - result <- NULL - message(paste0( - "Parcat3 [", - PARCAT3sel, - "] is not present on input dataset" - )) - return(result) - } - - ################################################################################ - # Set title - ################################################################################ - - result <- set_titles(result, titles2) - - if (save2rtf) { - ################################################################################ - # Convert to tbl file and output table - ################################################################################ - ### add the proper abbreviation to the tblid, and add opath path - fileid <- write_path(opath, tblidx) - - tt_to_tlgrtf( - colwidths = colwidth, - result, - file = fileid, - orientation = "landscape", - nosplitin = list(cols = c(trtvar, "rrisk_header")) - ) - } - - return(result) -} - - -################################################################################ -# Apply core function to all specified levels of parcat3 selection -# - General Chemistry (GC) -# - Kidney Function (KF) -# - Liver Biochemistry (LV) -# - Lipids (LP) -# - Hematology (HM) : -# Complete Blood Count -# WBC Differential -# Coagulation Studies -################################################################################ - -### note : the same core tblid (TSFLAB01) will be used for all, inside the core function build_result_parcat3 the proper abbreviation will be added - -result <- build_result_parcat3(PARCAT3sel = "General chemistry", tblid = tblid, save2rtf = FALSE) - -colwidth <- c(34, 27, 42, 47, 27, 42, 47, 27, 42, 49, 47, 47) - -tt_to_tlgrtf( - colwidths = colwidth, - result, - file = fileid, - orientation = "landscape", - nosplitin = list(cols = c(trtvar, "rrisk_header")) -) diff --git a/tests/testthat/source_code/tsflab01a.R b/tests/testthat/source_code/tsflab01a.R deleted file mode 100644 index aaff3455..00000000 --- a/tests/testthat/source_code/tsflab01a.R +++ /dev/null @@ -1,731 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab01a -## R version: 4.2.1 -## Short Description: Program to create tsflab01: Mean Change From Baseline -## for [Laboratory Category] Laboratory Data Over Time -## by [Subgroup] -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab01a.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFLAB01a" -fileid <- write_path(opath, tblid) -titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -popfl <- "SAFFL" -trtvar <- "TRT01A" -ctrl_grp <- "Placebo" - -# Note on ancova parameter -# when ancova = TRUE -# ancova model will be used to calculate all mean/mean change columns -# not just those from the Difference column -# model specification -summ_vars <- list(arm = trtvar, covariates = NULL) - -# when ancova = FALSE, all mean/mean change columns will be from descriptive stats -# for the difference column descriptive stats will be based upon two-sample t-test -ancova <- FALSE - - -comp_btw_group <- TRUE - - -subgrpvar <- "AGEGR1" -subgrplbl <- "Age: %s years" - -page_by <- TRUE # Set page_by TRUE/FALSE if you (do not) wish to start a new page after a new subgroup -indent_adj <- 0L -if (page_by) { - indent_adj <- 1L -} - -## For analysis on SI units: use adlb dataset -## For analysis on Conventional units: use adlbc dataset -- shell is in conventional units - -ad_domain <- "ADLB" - -# see further, an alternative method to identify all non-unscheduled visits based upon data -selvisit <- c("Screening", "Baseline", "Cycle 02", "Cycle 03", "Cycle 04") - -### note : this shell covers multiple tables depending on parcat3 selections - -## allowed PARCAT3 selections - -# parcat3sel <- "General chemistry" -# parcat3sel <- "Kidney function" -# parcat3sel <- "Liver biochemistry" -# parcat3sel <- "Lipids" -# -# ### Hematology (HM) : has 3 subcategories that should be included on one table -# parcat3sel <- c("Complete blood count","WBC differential","Coagulation studies") - -# per DPS specifications, the output identifier should include the abbreviation for the category - -# 1. Present laboratory tests using separate outputs for each category as follows: -# General chemistry (GC): Sodium, Potassium, Chloride, Bicarbonate, Urea Nitrogen, Glucose, Calcium, Magnesium, Phosphate, Protein, Albumin, Creatine Kinase, Amylase, Lipase -# Kidney function (KF): Creatinine, GFR from Creatinine -# Liver biochemistry (LV): Alkaline Phosphatase, Alanine Aminotransferase, Aspartate Aminotransferase, Bilirubin, Prothrombin Intl. Normalized Ratio, Gamma Glutamyl Transferase -# Lipids (LP): Cholesterol, HDL Cholesterol, LDL Cholesterol, Triglycerides -# Hematology (HM): Subcategory rows should be included for Complete Blood Count, White Blood Cell Differential and for Coagulation Studies -# Complete blood count: Leukocytes, Hemoglobin, Platelets; -# WBC differential: Lymphocytes, Neutrophils, Eosinophils; -# Coagulation studies: Prothrombin Time, Activated Partial Thromboplastin Time. - -# The output identifier should include the abbreviation for the laboratory category (eg, TSFLAB02GC for General Chemistry) - -# In current template program, only 1 version is created, without the proper abbreviation appended -# The reason for this is that TSFLAB02GC is not included in the DPS system - only the core version TSFLAB02 - -get_abbreviation <- function(parcat3sel) { - parcat3sel <- toupper(parcat3sel) - abbr <- NULL - if (length(parcat3sel) == 1) { - if (parcat3sel == toupper("General chemistry")) { - abbr <- "GC" - } - # the following line should be removed for a true study, global jjcs standards in DPS system does not include the abbreviation - if (parcat3sel == toupper("General chemistry")) { - abbr <- "" - } - # - if (parcat3sel == toupper("Kidney function")) { - abbr <- "KF" - } - if (parcat3sel == toupper("Liver biochemistry")) { - abbr <- "LV" - } - if (parcat3sel == toupper("Lipids")) abbr <- "LP" - } - if (length(parcat3sel) > 1) { - if ( - all( - parcat3sel %in% - toupper(c( - "Complete blood count", - "WBC differential", - "Coagulation studies" - )) - ) - ) { - abbr <- "HM" - } - } - - if (is.null(abbr)) { - message("Incorrect specification of parcat3sel") - } - - abbr -} - -get_tblid <- function(tblid, parcat3sel, method = c("after", "inbetween")) { - abbr <- get_abbreviation(parcat3sel) - - method <- match.arg(method) - # when inbetween, the abbreviation will be added prior to the number part of the table identifier - # when after (default), the abbreviation will be added at the end of the table identifier - - x <- 0 - if (method == "inbetween") { - x <- regexpr(pattern = "[0-9]", tblid)[1] - } - - if (x > 0) { - tblid1 <- substr(tblid, 1, x - 1) - tblid2 <- substring(tblid, x) - tblid_new <- paste0(tblid1, abbr, tblid2) - } else { - tblid_new <- paste0(tblid, abbr) - } - - return(tblid_new) -} - -## parcat3 options : -# current data: Liver biochemistry, General chemistry, Lipids, Kidney function, Complete blood count, WBC differential -# according shell: General chemistry, Kidney function, Liver biochemistry, Lipids, Hematology - -## not in shell: Complete blood count, WBC differential -## not in data: Hematology - -availparcat3 <- c( - "General chemistry", - "Kidney function", - "Liver biochemistry", - "Lipids", - "Complete blood count", - "WBC differential", - "" -) - - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select( - STUDYID, - USUBJID, - all_of(c(popfl, trtvar, subgrpvar)), - SEX, - AGEGR1, - RACE, - ETHNIC, - AGE - ) - -msubgrp <- adsl %>% - group_by(across(all_of(c(trtvar, subgrpvar)))) %>% - summarize(count = n()) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -adsl$rrisk_header <- "Difference in Mean Change (95% CI)" -adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) - - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - - -## For analysis on SI units: use adlb dataset -adlb_complete <- adlb_jnj - -# selection of all non-unscheduled visits from data -visits <- adlb_complete %>% - select(AVISIT) %>% - filter(!grepl("UNSCHEDULED", toupper(AVISIT))) - -visits$AVISIT <- droplevels(visits$AVISIT) -selvisit_data <- levels(visits$AVISIT) - -### if preferred to get it from data, rather than hardcoded list of visits -# selvisit <- selvisit_data - -adlb00 <- adlb_complete %>% - select( - USUBJID, - AVISITN, - AVISIT, - starts_with("PAR"), - AVAL, - BASE, - CHG, - PCHG, - starts_with("ANL"), - ABLFL, - APOBLFL - ) %>% - mutate(inlbdata = "Y") %>% - inner_join(adsl) %>% - relocate(USUBJID, PARAMCD, AVISIT, ANL02FL, ABLFL, APOBLFL) - -parcat <- unique(adlb00 %>% select(starts_with("PARCAT"), PARAMCD, PARAM)) - -## retrieve the precision of AVAL on the input dataset -## review outcome and make updates manually if needed -## the precision variable will be used for the parameter-based formats in layout - -## decimal = 4 is a cap in this derivation: if decimal precision of variable > decimal, the result will end up as decimal -## eg if AVAL has precision of 6 for parameter x, and decimal = 4, the resulting decimal value for parameter x is 4 - -## note that precision is on the raw values, as we are presenting mean/ci, and extra digit will be added -## eg precision = 2 will result in mean/ci format xx.xxx (xx.xxx, xx.xxx) - -lb_precision <- tidytlg:::make_precision_data( - df = adlb00, - decimal = 3, - precisionby = "PARAMCD", - precisionon = "AVAL" -) - -### data preparation - -filtered_adlb_00 <- adlb00 %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) - -#### perform check on unique record per subject/param/timepoint -check_unique <- filtered_adlb_00 %>% - group_by(USUBJID, PARAMCD, AVISIT) %>% - mutate(n_recsub = n()) %>% - filter(n_recsub > 1) - -#### perform check on unique record per subject/param/timepoint -check_unique <- filtered_adlb_00 %>% - group_by(USUBJID, PARAMCD, AVISIT) %>% - mutate(n_recsub = n()) %>% - filter(n_recsub > 1) - -if (nrow(check_unique) > 0) { - stop( - "Your input dataset needs extra attention, as some subjects have more than one record per parameter/visit" - ) - ### you will run into issues with fraction portion in count_denom_fraction, as count > denom, and fraction > 1 if you don't adjust your input dataset - - # Possible extra derivation - just to ensure program can run without issues - ### Study team is responsible for adding this derivation onto ADaM dataset and ensure proper derivation rule for ANL02FL is implemented !!!!!!!!!! - filtered_adlb_00x <- adlb00 %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) %>% - group_by(USUBJID, PARAM, AVISIT) %>% - mutate(n_sub = n()) %>% - arrange(USUBJID, PARAM, AVISIT, ADT) %>% - mutate(i = vctrs::vec_group_id(ADT)) %>% - mutate( - ANL02FL = case_when( - n_sub == 1 ~ "Y", - i == 1 ~ "Y" - ) - ) %>% - select(-c(i, n_sub)) %>% - ungroup() - - filtered_adlb_00 <- filtered_adlb_00x %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) - - ## now your data should contain 1 record per subject per parameter -} - -### for denominator per timepoint: all records from adlb on this timepoint: ignoring anl01fl/anl02fl/param -filtered_adlb_timepoints <- unique( - adlb00 %>% - filter(AVISIT %in% selvisit) %>% - select(USUBJID, AVISITN, AVISIT, inlbdata) -) %>% - inner_join(adsl) - - -################################################################################ -# Core function to produce shell for specific parcat3 selection -################################################################################ - -build_result_parcat3 <- function( - df = filtered_adlb_00, - df_timepoints = filtered_adlb_timepoints, - df_timepoints_subgroups = adlb_timepoints_subgroups, - df_orig = adlb00, - PARCAT3sel = NULL, - .adsl = adsl, - tblid, - save2rtf = TRUE, - .summ_vars = summ_vars, - .trtvar = trtvar, - .ref_path = ref_path, - .ctrl_grp = ctrl_grp, - .subgrpvar = subgrpvar, - .subgrplbl = subgrplbl, - .page_by = page_by, - .selvisit = selvisit -) { - tblidx <- get_tblid(tblid, PARCAT3sel) - titles2 <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" - ) - - .ctrl_grp <- utils::tail(.ref_path, n = 1) - multivars <- c("AVAL", "AVAL", "CHG") - - extra_args_3col <- list( - format_na_str = rep("NA", 3), - d = "decimal", - ref_path = .ref_path, - ancova = ancova, - comp_btw_group = comp_btw_group, - indatavar = "inlbdata", - multivars = multivars - ) - - ### continue with data preparation - if (!is.null(PARCAT3sel)) { - df <- df %>% - filter(PARCAT3 %in% PARCAT3sel) - } - - params <- unique(df %>% select(PARAMCD, PARAM)) - selparamcd <- params$PARAMCD - sel_param <- params$PARAM - - df_timepoints <- df_timepoints %>% - mutate(dummy_join = 1) %>% - full_join( - params %>% mutate(dummy_join = 1), - relationship = "many-to-many" - ) %>% - select(-dummy_join) - - ### identify subjects in df_timepoints and not in df - - extra_sub <- anti_join(df_timepoints, df) %>% - mutate(extra_sub = "Y") - - attr(extra_sub$extra_sub, "label") <- "Extra Subject step 1" - - ### only add these extra_sub to - ### this will ensure we still meet the one record per subject per timepoint - ### this will ensure length(x) can be used for the denominator derivation inside summarize_aval_chg_diff function - - df <- bind_rows(df, extra_sub) %>% - arrange(USUBJID, PARAM, AVISITN) - - df <- df %>% - inner_join(lb_precision, by = "PARAMCD") - - #### Only In case we want the subgroup N to come from ADSL, and not just from ADVS - - ### also add adsl subjects that have no vs data --- for subgroup counts from adsl - - adlb_timepoints_subgroups <- - .adsl %>% - select(USUBJID) %>% - # define factor PARAMCD/AVISIT with one category, all levels we need - mutate( - PARAMCD = factor(selparamcd[1], levels = selparamcd), - AVISIT = factor(.selvisit[1], levels = .selvisit) - ) %>% - # expand dataset to show all levels - tidyr::complete(., USUBJID, PARAMCD, AVISIT) - - extra_sub2 <- - anti_join( - df_timepoints_subgroups, - df %>% select(USUBJID, AVISITN, AVISIT, PARAMCD, PARAM) - ) %>% - left_join( - ., - unique(df_orig %>% select(AVISITN, AVISIT, PARAMCD, PARAM)) - ) %>% - anti_join(., extra_sub) %>% - inner_join(.adsl) %>% - mutate(extra_sub2 = "Y") - - attr(extra_sub2$extra_sub2, "label") <- "Extra Subject step 2" - - ### add these extra_sub dataframe as well - ### this will ensure we still meet the one record per subject per timepoint - ### However, by adding also subjects without data in vs, we can no longer use length(x) for the denominator derivation inside summarize_aval_chg_diff function - df <- bind_rows(df, extra_sub2) %>% - arrange(USUBJID, PARAM, AVISITN) - - ### important: previous actions lost the label of variables - ### in order to be able to use obj_label(filtered_adlb$PARAM) in layout, need to redefine the label - - ## do these 2 manually, as these are not available on advs00 - attr(df$extra_sub, "label") <- "Extra Subject step 1" - attr(df$extra_sub2, "label") <- "Extra Subject step 2" - - df <- var_relabel_list(df, var_labels(df_orig, fill = T)) %>% - relocate(USUBJID, PARAMCD, PARAM, AVISIT, AGEGR1, AVAL, CHG) - - df$PARAM <- factor(as.character(df$PARAM), levels = sel_param) - - ### important: previous actions lost the label of variables - ### in order to be able to use obj_label(filtered_adlb$PARAM) in layout, need to redefine the label - df <- var_relabel_list(df, var_labels(df_orig, fill = T)) - - ################################################################################ - # Define layout and build table: - ################################################################################ - - lyt <- basic_table(show_colcounts = FALSE, colcount_format = "N=xx") %>% - ### first columns - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(.trtvar, show_colcounts = TRUE, colcount_format = "N=xx") %>% - split_rows_by( - .subgrpvar, - label_pos = "hidden", - section_div = " ", - split_fun = drop_split_levels, - page_by = .page_by - ) %>% - ### just show number of subjects in current level of subgrpvar - ### only show this number in the first AVAL column - summarize_row_groups( - var = .subgrpvar, - cfun = a_freq_j, - extra_args = list( - label_fstr = .subgrplbl, - extrablankline = TRUE, - restr_columns = "AVAL", - .stats = c("n_altdf"), - riskdiff = FALSE, - denom_by = subgrpvar - ) - ) %>% - split_rows_by( - "PARAM", - label_pos = "topleft", - split_label = "Laboratory Test", - section_div = " ", - split_fun = drop_split_levels - ) %>% - ## note the child_labels = hidden for AVISIT, these labels will be taken care off by - ## applying function summarize_aval_chg_diff further in the layout - split_rows_by( - "AVISIT", - label_pos = "topleft", - split_label = "Study Visit", - split_fun = drop_split_levels, - child_labels = "hidden" - ) %>% - ## set up a 3 column split - split_cols_by_multivar( - multivars, - varlabels = c( - "n/N (%)", - "Mean (95% CI)", - "Mean Change From Baseline (95% CI)" - ) - ) %>% - ### restart for the rrisk_header columns - note the nested = FALSE option - ### also note the child_labels = "hidden" in both PARAM and AVISIT - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - .trtvar, - split_fun = remove_split_levels(.ctrl_grp), - labels_var = "rrisk_label", - show_colcounts = TRUE, - colcount_format = "N=xx" - ) %>% - ### difference columns : just 1 column & analysis needs to be done on change - split_cols_by_multivar(multivars[3], varlabels = c(" ")) %>% - ### the variable passed here in analyze is not used (STUDYID), it is a dummy var passing, - ### the function summarize_aval_chg_diff grabs the required vars from cols_by_multivar calls - analyze( - "STUDYID", - afun = a_summarize_aval_chg_diff_j, - extra_args = extra_args_3col - ) - - if (nrow(df) > 0) { - result <- build_table(lyt, df, alt_counts_df = .adsl) - - ################################################################################ - # Post-Processing: - # - Prune table to remove when n = 0 in all columns - # - Remove the N=xx column headers for the difference vs PBO columns - ################################################################################ - - ### alhtough this is not really likely to occur in real data, this is a problem in the current synthetic data - ### also here, try to remove this issue - - # rps_result <- row_paths_summary(result) - - ### below code is based upon tern pruning function has_count_in_any_col, with updates to internal function h_row_first_values for the 3 column - format we are using here - - my_has_count_in_any_col <- function(atleast, ...) { - checkmate::assert_count(atleast) - CombinationFunction(function(table_row) { - row_counts <- my_h_row_counts(table_row, ...) - ### small update compared to tern::has_count_in_any_col - ## > vs >= - any(row_counts > atleast) - }) - } - - my_h_row_counts <- - function(table_row, col_names = NULL, col_indices = NULL) { - ## no updates compared to tern::h_row_counts, beyond using the customized my_h_row_first_values function - counts <- my_h_row_first_values(table_row, col_names, col_indices) - checkmate::assert_integerish(counts) - counts - } - - my_h_row_first_values <- function(table_row, - col_names = NULL, - col_indices = NULL) { - col_indices <- tern:::check_names_indices( - table_row, - col_names, - col_indices - ) - checkmate::assert_integerish(col_indices) - checkmate::assert_subset(col_indices, seq_len(ncol(table_row))) - - # Main values are extracted - row_vals <- row_values(table_row)[col_indices] - - ### specific updates to current situation -- 3 column layout, I want to grab the information from the n/N column, which is in first analysis of AVAL - specific_cols <- names(row_vals) - specific_cols <- specific_cols[stringr::str_ends(specific_cols, "AVAL")] - - row_vals <- row_vals[specific_cols] - - # Main return - vapply( - row_vals, - function(rv) { - if (is.null(rv)) { - NA_real_ - } else { - rv[1L] - } - }, - FUN.VALUE = numeric(1) - ) - } - - more_than_0 <- my_has_count_in_any_col(atleast = 0) - - ## seem to work ok, not clear why it goes through each row twice? - result <- prune_table(result, keep_rows(more_than_0)) - - ## Remove the N=xx column headers for the difference vs PBO columns - remove_col_count2 <- function(result, string = paste("vs", ctrl_grp)) { - mcdf <- make_col_df(result, visible_only = FALSE) - mcdfsel <- mcdf %>% - filter(stringr::str_detect(toupper(label), toupper(string))) %>% - pull(path) - - for (i in seq_along(mcdfsel)) { - facet_colcount(result, mcdfsel[[i]]) <- NA - } - - return(result) - } - - result <- remove_col_count2(result) - } else { - result <- NULL - message(paste0( - "Parcat3 [", - PARCAT3sel, - "] is not present on input dataset" - )) - return(result) - } - - ################################################################################ - # Set title - ################################################################################ - - result <- set_titles(result, titles2) - - if (save2rtf) { - ################################################################################ - # Convert to tbl file and output table - ################################################################################ - ### add the proper abbreviation to the tblid, and add opath path - fileid <- write_path(opath, tblidx) - - tt_to_tlgrtf( - colwidths = colwidth, - result, - file = fileid, - orientation = "landscape", - nosplitin = list(cols = c(.trtvar, "rrisk_header")) - ) - } - - return(result) -} - - -################################################################################ -# Apply core function to all specified levels of parcat3 selection -# - General Chemistry (GC) -# - Kidney Function (KF) -# - Liver Biochemistry (LV) -# - Lipids (LP) -# - Hematology (HM) : -# Complete Blood Count -# WBC Differential -# Coagulation Studies -################################################################################ - -### note : the same core tblid (TSFLAB01a) will be used for all, inside the core function build_result_parcat3 the proper abbreviation will be added - -### titles will not be retrieved for these, as the table identifiers are not in the DPS system -### study teams will have to ensure all versions that are needed are included in DPS system -# result1 <- build_result_parcat3( -# PARCAT3sel = "Liver biochemistry", -# tblid = tblid, -# save2rtf = TRUE -# ) -# result2 <- build_result_parcat3( -# PARCAT3sel = "Kidney function", -# tblid = tblid, -# save2rtf = TRUE -# ) -# result3 <- build_result_parcat3( -# PARCAT3sel = "Lipids", -# tblid = tblid, -# save2rtf = TRUE -# ) -# -# result4 <- build_result_parcat3( -# PARCAT3sel = c( -# "Complete blood count", -# "WBC differential", -# "Coagulation studies" -# ), -# tblid = tblid, -# save2rtf = TRUE -# ) - -### if a certain category is not present, no rtf will be generated - -result <- build_result_parcat3(PARCAT3sel = "General chemistry", tblid = tblid, save2rtf = FALSE) - -colwidth <- c(39, 29, 46, 47, 29, 46, 47, 29, 46, 48, 47, 49) - -tt_to_tlgrtf( - colwidths = colwidth, - result, - file = fileid, - orientation = "landscape", - nosplitin = list(cols = c(trtvar, "rrisk_header")) -) diff --git a/tests/testthat/source_code/tsflab01b.R b/tests/testthat/source_code/tsflab01b.R new file mode 100644 index 00000000..68286df4 --- /dev/null +++ b/tests/testthat/source_code/tsflab01b.R @@ -0,0 +1,414 @@ +library(envsetup) +library(dplyr) +library(rtables) +library(junco) +library(haven) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFLAB01b" +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +# Population flag (default=SAFFL). +popfl <- "SAFFL" + +# Actual treatment variable (default=TRT01A). +trtvar <- "TRT01A" + +# Control arm name (one of the levels of the treatment variable). +ctrl_grp <- "Placebo" + +# Lab parameters Category of interest on PARCAT1 (name = file suffix). +param_cat <- c(chm = "CHEMISTRY") # , hem = "HEMATOLOGY") + +# Lab sign parameters of interest. +param_cd <- NULL + +# Non-baseline visits of interest. +nonbl_visits <- c("Cycle 02", "Cycle 04", "Cycle 03") + +# Flag to enable comparison between treatment groups (e.g., mean difference vs. control). +comp_btw_group <- TRUE + +# Add Active Study Agent Combined column +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +################################################################################ +# Process data: +################################################################################ + +adsl <- pharmaverseadamjnj::adsl |> + select(USUBJID, all_of(c(popfl, trtvar))) |> + filter( + toupper(.data[[popfl]]) == "Y", + !is.na(.data[[trtvar]]) + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) + +adlb <- pharmaverseadamjnj::adlb |> + select( + USUBJID, + all_of(c(popfl, trtvar)), + AVISITN, + AVISIT, + ATPT, + PARAMCD, + PARAM, + PARAMN, + PARCAT1, + PARCAT3, + PARCAT3N, + AVAL, + BASE, + CHG, + starts_with("ANL"), + ABLFL, + APOBLFL + ) |> + filter( + (.data[[popfl]] == "Y"), + !is.na(.data[[trtvar]]), + if (!is.null(param_cat)) PARCAT1 %in% param_cat else TRUE, + if (!is.null(param_cd)) PARAMCD %in% param_cd else TRUE + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + ABLFL := factor(ifelse(ABLFL == "Y" & !is.na(ABLFL), "Y", "N")), + APOBLFL := factor(ifelse(APOBLFL == "Y" & !is.na(APOBLFL), "Y", "N")), + PARAMCD := ordered(PARAMCD, levels = { + # Sort by PARCAT3N then PARAMCD and PARCAT3 not displayed used only for sorting + unique(PARAMCD[order(PARCAT3N, PARAM)]) + }), + PARAM := ordered(PARAM, levels = { + # Sort by PARCAT3N then PARAM and PARCAT3 not displayed used only for sorting + unique(PARAM[order(PARCAT3N, PARAM)]) + }), + AVISIT = factor( + ifelse(ABLFL == "Y" & !is.na(ABLFL), "Baseline", as.character(AVISIT)), + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) + +# Reordered nonlbl_visits +nonbl_visits <- unique(as.character(adlb$AVISIT[adlb$AVISIT %in% nonbl_visits])) + +adlb <- inner_join(adsl, adlb, by = c("USUBJID", popfl, trtvar)) + +# Safety checks on the data. +adlb_checks_unique <- adlb |> + filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) |> + group_by(USUBJID, PARCAT1, PARAMCD, AVISIT) |> + mutate(n_recsub = n()) |> + filter(n_recsub > 1) + +if (nrow(adlb_checks_unique) > 0) { + stop( + "Your input dataset needs extra attention, as some subjects have more than one record per parameter/visit" + ) +} + +adlb_checked <- adlb |> + filter( + toupper(.data[[popfl]]) == "Y", + toupper(ANL01FL) == "Y", + toupper(ANL02FL) == "Y" + ) |> + mutate( + flag = if_else(is.na(AVAL), 1L, 0L), + flag1 = if_else(toupper(APOBLFL) == "Y" & is.na(BASE), 1L, 0L) + ) + +if (nrow(filter(adlb_checked, flag == 1)) > 0) { + message("Pay attention: There are tests with missing AVAL: ") +} + +if (nrow(filter(adlb_checked, flag1 == 1)) > 0) { + message("Pay attention: There are postbaseline tests without baseline: those will be removed") +} + +# Keep only records with non-missing AVAL +adlb <- filter(adlb, !is.na(AVAL)) + +# varying decimal precision ---- +# manual setup example +prec <- dplyr::tibble(PARAMCD = unique(adlb$PARAMCD), d = 1) +prec$d[prec$PARAMCD %in% c("ALB", "CA")] <- 2 + +# alternative: use tidytlg make_precision function +# DTYPE='AVERAGE' records are excluded from decimal precision +# adlb_avg <- adlb |> filter(!DTYPE=="AVERAGE") + +# prec2 <- tidytlg:::make_precision_data( +# df = adlb_avg, +# decimal = 4, +# precisionby = "PARAMCD", +# precisionon = "AVAL" +# ) |> +# rename(c(d = "decimal")) + +.stats_all <- c("n", "mean_sd", "median_range", "diff_means_est_ci") +# add d-based formats for all required stats onto precision dataset +prec <- fmt_spec_df_d( + prec, + d_column = "d", + fmt_column = "fmt_d", + stats_in = .stats_all, + fmt_d_def = junco_def_d_all, + fmt_d_in = NULL +) + +# review d-based formats +fmt_d_details <- lapply(prec$PARAMCD, FUN = function(x) { + fmt <- prec[prec$PARAMCD == x, ][["fmt_d"]][[1]] + get_fmt_details( + fmt, + as_tibble = TRUE + ) +}) +names(fmt_d_details) <- prec$PARAMCD +# fmt_d_details + +# add precision specific format to adlb input dataset +adlb <- adlb |> + left_join(prec) + +################################################################################ +# Define layout and build table (loop over categories): +################################################################################ + +cat_suffix <- param_cat +adlb_cat <- filter(adlb, PARCAT1 == param_cat[[1]]) |> + filter(ABLFL == "Y" | ANL02FL == "Y" | APOBLFL == "Y") +fileid <- write_path(opath, paste0(tblid)) + +colspan_trt_map <- if (!is.null(ctrl_grp)) { + create_colspan_map( + adlb_cat, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) +} else { + tibble( + colspan_trt = "Active Study Agent", + !!trtvar := levels(adlb[[trtvar]]) + ) +} + +# Common stats for time point / change from baseline to time point. +stats <- c("n", "mean_sd", "median_range") +formats <- junco_get_formats_from_stats(stats) +labels <- junco_get_labels_from_stats(stats, labels_in = c(n = "N")) +indent_mods <- c(n = 1L, mean_sd = 2L, median_range = 2L) + +# Dynamic label for the "Change from baseline ..." sections. +a_chg_label <- function(x, .spl_context) { + last_split <- length(.spl_context$split) + label <- paste("Change from baseline to", .spl_context$value[last_split]) + rtables::rcell(NULL, label = label) +} + +# Difference in means parameters. +CI_cl <- tern::control_analyze_vars()$conf_level +a_diff_means_args <- list( + ref_path = c("colspan_trt", " ", trtvar, ctrl_grp), + conf.level = CI_cl, + .stats = "diff_means_est_ci", + .formats = "default", + .labels = c( + diff_means_est_ci = paste0( + "Difference in mean vs. ", + tolower(ctrl_grp), + " (", + tern::f_conf_level(CI_cl), + ")" + ) + ) +) + +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx", + top_level_section_div = " " +) |> + append_topleft("Laboratory Test") |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +lyt <- lyt |> + split_rows_by( + "PARAMCD", + split_fun = if (!is.null(param_cd)) keep_split_levels(param_cd) else drop_split_levels, + labels_var = "PARAM", + child_labels = "visible" + ) |> + summarize_row_groups( + "AVAL", + cfun = c_summary_subset_label, + extra_args = list( + filter_expr = expression(ABLFL == "Y"), + .stats = stats, + .formats = "default", + formats_var = "fmt_d", + .labels = labels, + .indent_mods = indent_mods, + label = "Baseline" + ) + ) |> + split_rows_by( + "AVISIT", + split_fun = if (!is.null(nonbl_visits)) keep_split_levels(nonbl_visits) else drop_split_levels, + indent_mod = -1, + section_div = " ", + ) |> + analyze( + "AVAL", + afun = tern::a_summary, + extra_args = list( + .stats = stats, + .formats = "default", + .labels = labels, + .indent_mods = indent_mods - 1, + na_rm = TRUE + ), + formats_var = "fmt_d", + show_labels = "hidden", + section_div = " " + ) |> + analyze( + "CHG", + afun = a_chg_label, + table_names = "chg_bl_label", + show_labels = "hidden", + indent_mod = -1L + ) |> + analyze( + "CHG", + afun = tern::a_summary, + extra_args = list( + .stats = "n", + .formats = "default", + .labels = labels, + na_rm = TRUE # Subjects with non-missing values at both baseline and the postbaseline time point. + ), + formats_var = "fmt_d", + show_labels = "hidden" + ) |> + analyze( + "BASE", + afun = a_summary_subset, + extra_args = list( + filter_expr = expression(!is.na(CHG)), + na_rm = TRUE, + .stats = "mean_sd", + .formats = "default", + .labels = c(mean_sd = "Baseline mean (SD)") + ), + formats_var = "fmt_d", + table_names = "chg_bl_mean", + show_labels = "hidden", + indent_mod = 1L + ) |> + analyze( + "CHG", + afun = tern::a_summary, + extra_args = list( + .stats = c("mean_sd", "median_range"), + .formats = "default", + .labels = labels, + na_rm = TRUE + ), + formats_var = "fmt_d", + table_names = "chg_mm", + show_labels = "hidden", + indent_mod = 1L + ) + +if (comp_btw_group) { + lyt <- lyt |> + analyze( + "CHG", + afun = a_diff_means, + extra_args = a_diff_means_args, + formats_var = "fmt_d", + table_names = "chg_diff_means", + show_labels = "hidden", + indent_mod = 1L + ) +} + +result <- build_table(lyt, adlb_cat, alt_counts_df = adsl, round_type = "sas") + +# Add an empty line after each "Screening" section. +# Use `section_div_at_path()` as a workaround for the missing +# `section_div` argument in `summarize_row_groups()`. +# (Feature request: https://github.com/insightsengineering/rtables/issues/1083) +# The path below is determined from `rtables::row_paths_summary(result)`. +section_div_at_path(result, c("PARAMCD", "*", "@content", last(stats))) <- " " + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 37, 37, 37, 34) + +x <- tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab02.R b/tests/testthat/source_code/tsflab02.R index c91a596d..d679b8f7 100644 --- a/tests/testthat/source_code/tsflab02.R +++ b/tests/testthat/source_code/tsflab02.R @@ -1,50 +1,9 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab02 -## R version: 4.2.1 -## Short Description: Program to create tsflab02: Subjects With ≥1 [Laboratory Category] -## Laboratory Values With Elevated or Low Values -## Meeting Specified Levels Based on Worst On-treatment Value -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab02.rtf -## Multiple tables are generated using this script -## These tables should be defined in Autocode (or titles file) as separate tables -## -tsflab02gc General chemistry -## -tsflab02kf Kidney function -## -tsflab02lv Liver biochemistry -## -tsflab02lp Lipids -## -tsflab02hm Hematology -## -## Remarks: Should only be used when abnormalities are based upon markedly abnormal file -## carefully review factor levels of variables MCRIT1/MCRIT2 and MCRIT1ML/MCRIT2ML on your input adlb.rds dataset -## Pay special attention to the following tests: -## Especially check if N is correct (review ADaM derivation for these params) -## GLUC : Glucose, high : LBFAST is part of condition -## HDL : separate levels for male/female -## HGB : separate levels for male/female -## -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Define script level parameters: -################################################################################ - ################################################################################ # Prep Environment ################################################################################ library(envsetup) library(tern) -library(tern) library(dplyr) library(rtables) library(tidytlg) @@ -58,120 +17,57 @@ library(junco) tblid <- "TSFLAB02" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) +# Population flag variable (default=SAFFL). popfl <- "SAFFL" +# Actual treatment variable (default=TRT01A). trtvar <- "TRT01A" -ctrl_grp <- "Placebo" - - -### note : this shell covers multiple tables depending on parcat3 selections - -## allowed PARCAT3 selections - -# parcat3sel <- "General chemistry" -# parcat3sel <- "Kidney function" -# parcat3sel <- "Liver biochemistry" -# parcat3sel <- "Lipids" -# -# ### Hematology (HM) : has 3 subcategories that should be included on one table -# parcat3sel <- c("Complete blood count","WBC differential","Coagulation studies") - -# per DPS specifications, the output identifier should include the abbreviation for the category - -# 1. Present laboratory tests using separate outputs for each category as follows: -# General chemistry (GC): Sodium, Potassium, Chloride, Bicarbonate, Urea Nitrogen, Glucose, Calcium, Magnesium, Phosphate, Protein, Albumin, Creatine Kinase, Amylase, Lipase -# Kidney function (KF): Creatinine, GFR from Creatinine -# Liver biochemistry (LV): Alkaline Phosphatase, Alanine Aminotransferase, Aspartate Aminotransferase, Bilirubin, Prothrombin Intl. Normalized Ratio, Gamma Glutamyl Transferase -# Lipids (LP): Cholesterol, HDL Cholesterol, LDL Cholesterol, Triglycerides -# Hematology (HM): Subcategory rows should be included for Complete Blood Count, White Blood Cell Differential and for Coagulation Studies -# Complete blood count: Leukocytes, Hemoglobin, Platelets; -# WBC differential: Lymphocytes, Neutrophils, Eosinophils; -# Coagulation studies: Prothrombin Time, Activated Partial Thromboplastin Time. - -# The output identifier should include the abbreviation for the laboratory category (eg, TSFLAB02GC for General Chemistry) - -# In current template program, only 1 version is created, without the proper abbreviation appended -# The reason for this is that TSFLAB02GC is not included in the DPS system - only the core version TSFLAB02 - -get_abbreviation <- function(parcat3sel) { - parcat3sel <- toupper(parcat3sel) - abbr <- NULL - if (length(parcat3sel) == 1) { - if (parcat3sel == toupper("General chemistry")) { - abbr <- "GC" - } - # the following line should be removed for a true study, global jjcs standards in DPS system does not include the abbreviation - if (parcat3sel == toupper("General chemistry")) { - abbr <- "" - } - # - if (parcat3sel == toupper("Kidney function")) { - abbr <- "KF" - } - if (parcat3sel == toupper("Liver biochemistry")) { - abbr <- "LV" - } - if (parcat3sel == toupper("Lipids")) abbr <- "LP" - } - if (length(parcat3sel) > 1) { - if ( - all( - parcat3sel %in% - toupper(c( - "Complete blood count", - "WBC differential", - "Coagulation studies" - )) - ) - ) { - abbr <- "HM" - } - } - - if (is.null(abbr)) { - message("Incorrect specification of parcat3sel") - } - - abbr -} -get_tblid <- function(tblid, parcat3sel, method = c("after", "inbetween")) { - abbr <- get_abbreviation(parcat3sel) +ctrl_grp <- "Placebo" - method <- match.arg(method) - # when inbetween, the abbreviation will be added prior to the number part of the table identifier - # when after (default), the abbreviation will be added at the end of the table identifier +# Add Active Study Agent Combined column +combined_colspan_trt <- TRUE - x <- 0 - if (method == "inbetween") { - x <- regexpr(pattern = "[0-9]", tblid)[1] - } +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) - if (x > 0) { - tblid1 <- substr(tblid, 1, x - 1) - tblid2 <- substring(tblid, x) - tblid_new <- paste0(tblid1, abbr, tblid2) - } else { - tblid_new <- paste0(tblid, abbr) - } + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) - return(tblid_new) + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) } - -### the varying fileid will be handled at the end of the program, as this program will generate all levels +# PARCAT1 categories to produce: CHEMISTRY -> CHM, HEMATOLOGY -> HM +parcat1_categories <- list( + chm = "CHEMISTRY", + hem = "HEMATOLOGY" +) ad_domain <- "adlb" - ## if the option TRTEMFL needs to be added to the TLF -- ensure the same setting as in tsflab04 trtemfl <- TRUE +## ANL flag variable for low grade +anl_low_fl <- "ANL04FL" + +## ANL flag variable for high grade +anl_high_fl <- "ANL05FL" + + ################################################################################ # Initial processing of data + check if table is valid for trial: ################################################################################ @@ -184,29 +80,31 @@ adlb_complete <- adlb_jnj ### Markedly Abnormal spreadsheet -markedlyabnormal_file <- file.path(datapath, "markedlyabnormal.xlsx") +markedlyabnormal_file <- read_path(datapath, "markedlyabnormal.xlsx") + +markedlyabnormal_sheets <- readxl::excel_sheets(markedlyabnormal_file) lbmarkedlyabnormal_defs <- readxl::read_excel( markedlyabnormal_file, sheet = toupper(ad_domain) -) %>% +) |> filter(PARAMCD != "Parameter Code") MCRITs <- unique( - lbmarkedlyabnormal_defs %>% - filter(!stringr::str_ends(VARNAME, "ML")) %>% + lbmarkedlyabnormal_defs |> + filter(!stringr::str_ends(VARNAME, "ML")) |> pull(VARNAME) ) MCRITs_def <- unique( - lbmarkedlyabnormal_defs %>% - filter(VARNAME %in% MCRITs) %>% + lbmarkedlyabnormal_defs |> + filter(VARNAME %in% MCRITs) |> select(PARAMCD, VARNAME, CRIT, SEX) -) %>% - mutate(VARNAME = paste0(VARNAME, "ML")) %>% - rename(CRITNAME = CRIT) %>% +) |> + mutate(VARNAME = paste0(VARNAME, "ML")) |> + rename(CRITNAME = CRIT) |> mutate( CRITDIR = case_when( VARNAME == "MCRIT1ML" ~ "DIR1", @@ -215,25 +113,25 @@ MCRITs_def <- unique( ) -MCRITs_def2 <- lbmarkedlyabnormal_defs %>% - filter(VARNAME %in% paste0(MCRITs, "ML")) %>% +MCRITs_def2 <- lbmarkedlyabnormal_defs |> + filter(VARNAME %in% paste0(MCRITs, "ML")) |> mutate(CRITn = as.character(4 - as.numeric(ORDER))) -MCRITs_def3 <- MCRITs_def2 %>% - left_join(., MCRITs_def, relationship = "many-to-one") %>% - select(PARAMCD, CRITNAME, CRITDIR, SEX, VARNAME, CRIT, CRITn) %>% - arrange(PARAMCD, VARNAME, CRITDIR, SEX, CRITn) %>% +MCRITs_def3 <- MCRITs_def2 |> + left_join(MCRITs_def, relationship = "many-to-one") |> + select(PARAMCD, CRITNAME, CRITDIR, SEX, VARNAME, CRIT, CRITn) |> + arrange(PARAMCD, VARNAME, CRITDIR, SEX, CRITn) |> select(-SEX) ### convert dataframe into label_map that can be used with the a_freq_j afun function -xlabel_map <- MCRITs_def3 %>% - rename(var = VARNAME, label = CRIT) %>% +xlabel_map <- MCRITs_def3 |> + rename(var = VARNAME, label = CRIT) |> select(PARAMCD, CRITNAME, CRITDIR, var, label) -xlabel_map2 <- xlabel_map %>% +xlabel_map2 <- xlabel_map |> mutate( MCRIT12 = CRITNAME, MCRIT12ML = label @@ -244,8 +142,14 @@ xlabel_map2 <- xlabel_map %>% # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> select(USUBJID, all_of(c(popfl, trtvar))) adsl$colspan_trt <- factor( @@ -271,16 +175,18 @@ obs_mcrit12 <- unique(c( unique(adlb_complete$MCRIT2) )) -adlb00 <- adlb_complete %>% +adlb00 <- adlb_complete |> filter( - SAFFL == "Y" & - PARCAT2 == "Test with FDA abnormality criteria defined" - ) %>% + .data[[popfl]] == "Y" & + PARCAT2 == "Test with FDA abnormality criteria defined" & + toupper(PARCAT1) %in% toupper(unlist(parcat1_categories)) + ) |> select( USUBJID, PARCAT1, PARCAT2, PARCAT3, + PARCAT3N, ONTRTFL, TRTEMFL, PARAM, @@ -292,89 +198,93 @@ adlb00 <- adlb_complete %>% MCRIT1ML, MCRIT2, MCRIT2ML, - ONTRTFL, - TRTEMFL, LVOTFL, ANL01FL, ANL02FL, - ANL04FL, - ANL05FL + all_of(c(anl_low_fl, anl_high_fl)) ### if per period/phase is needed, use below flag variables # ,ANL07FL,ANL08FL,ANL09FL,ANL10FL - ) %>% + ) |> + arrange(PARCAT1, PARCAT3N, PARCAT3, PARAM) |> + mutate(PARAM = factor(as.character(PARAM), levels = unique(as.character(PARAM)))) |> inner_join(adsl) -combodf <- tribble( - ~valname, ~label, ~levelcombo, ~exargs, - "xan-comb", "Xanomeline Combined", c("Xanomeline High Dose", "Xanomeline Low Dose"), list() -) - ################################################################################ -##### vertical approach for analyzing MCRIT1/MCRIT2: +##### Vertical approach for analyzing MCRIT1/MCRIT2: # filtering is easier, as well as the analyze/layout setup ################################################################################ -adlb_mcrit1 <- adlb00 %>% - filter(!is.na(MCRIT1)) %>% +adlb_mcrit1 <- adlb00 |> + filter(!is.na(MCRIT1)) |> mutate( MCRIT12 = MCRIT1, MCRIT12ML = MCRIT1ML, CRITDIR = "DIR1", - ANL045FL = ANL04FL + ANLHLFL = .data[[anl_low_fl]] ) -adlb_mcrit2 <- adlb00 %>% - filter(!is.na(MCRIT2)) %>% +adlb_mcrit2 <- adlb00 |> + filter(!is.na(MCRIT2)) |> mutate( MCRIT12 = MCRIT2, MCRIT12ML = MCRIT2ML, CRITDIR = "DIR2", - ANL045FL = ANL05FL + ANLHLFL = .data[[anl_high_fl]] ) -### note: by filter ANL04FL/ANL05FL, this table is restricted to On-treatment values, per definition of ANL04FL/ANL05FL +### note: by filter ANL04FL/ANL05FL (controlled by anl04fl/anl05fl parameters), this table is restricted to On-treatment values, per definition of ANL04FL/ANL05FL ### therefor, no need to add ONTRTFL in filter ### if derivation of ANL04FL/ANL05FL is not restricted to ONTRTFL records, adding ONTRTFL here will not give the correct answer either ### as mixing worst with other period is not giving the proper selection !!! -adlb_mcrit <- rbind(adlb_mcrit1, adlb_mcrit2) %>% - filter(ANL045FL == "Y") %>% - inner_join(., adsl) +adlb_mcrit <- rbind(adlb_mcrit1, adlb_mcrit2) |> + filter(ANLHLFL == "Y") |> + mutate( + PARAMCD := ordered(PARAMCD, levels = { + # Sort by PARCAT3N then PARAMCD and PARCAT3 not displayed used only for sorting + unique(PARAMCD[order(PARCAT3N, PARAM)]) + }), + AVISIT = factor( + .data[["AVISIT"]], + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) |> + inner_join(adsl) #### DO NOT USE TRTEMFL = Y in filter, as this will remove subjects from both numerator and denominator #### instead : set MCRIT12ML to a non-reportable value (ie Level 0) and keep in dataset if (trtemfl) { origlevs <- levels(adlb_mcrit$MCRIT12ML) - adlb_mcrit <- adlb_mcrit %>% + adlb_mcrit <- adlb_mcrit |> mutate( MCRIT12ML = case_when( !is.na(MCRIT12ML) & is.na(TRTEMFL) | TRTEMFL != "Y" ~ "Level 0", TRUE ~ MCRIT12ML ) - ) %>% + ) |> mutate(MCRIT12ML = factor(MCRIT12ML, levels = origlevs)) } ################################################################################ -##### finalize mapping dataframe based upon abnormal spreadsheet +##### Finalize mapping dataframe based upon abnormal spreadsheet ################################################################################ -xlabel_map3 <- xlabel_map2 %>% - right_join(., unique(adlb_mcrit %>% select(PARAMCD, PARCAT3))) %>% - arrange(PARCAT3, PARAMCD, CRITDIR, MCRIT12, MCRIT12ML) %>% - mutate_if(is.factor, as.character) %>% +xlabel_map3 <- xlabel_map2 |> + right_join(unique(adlb_mcrit |> select(PARAMCD, PARCAT1, PARCAT3, PARCAT3N))) |> + arrange(PARCAT1, PARCAT3N, PARAMCD, CRITDIR, MCRIT12, MCRIT12ML) |> + mutate_if(is.factor, as.character) |> #### get rid of mapping defined in spreadsheet but not present in data filter(MCRIT12 %in% obs_mcrit12) ### this will ensure alphabetical sorting on abnormality ### within a test LOW needs to come prior to High ### for this reason, split a test like 'Calcium, low' and 'Calcium, High' in 2 -xlabel_map3 <- xlabel_map3 %>% - mutate(MCRIT12x = stringr::str_split_i(MCRIT12, ",", 1)) %>% - arrange(MCRIT12x, CRITDIR, MCRIT12ML) +xlabel_map3 <- xlabel_map3 |> + mutate(MCRIT12x = stringr::str_split_i(MCRIT12, ",", 1)) |> + arrange(PARCAT1, PARCAT3N, MCRIT12x, CRITDIR, MCRIT12ML) # MCRIT12ML needs to be a factor, with all levels (also unobserved), @@ -395,112 +305,91 @@ adlb_mcrit$MCRIT12ML <- factor( method = "wald", denom = "n_df", ref_path = ref_path, - .stats = c("denom", "count_unique_fraction") + .stats = c("denom", "count_unique_fraction"), + na_str = "-" ) ################################################################################ -# Core function to produce shell for specific parcat3 selection +# Core function to produce table for a specific PARCAT1 selection +# Data sorted by PARCAT1 -> PARCAT3N -> PARAM ################################################################################ -build_result_parcat3 <- function( +build_result_parcat1 <- function( df = adlb_mcrit, - PARCAT3sel = NULL, + PARCAT1sel = NULL, + tblid, .adsl = adsl, map = xlabel_map3, - tblid, - save2rtf = TRUE, extra_args_rr = .extra_args_rr, .trtvar = trtvar, .ctrl_grp = ctrl_grp, - .ref_path = ref_path + .combined_colspan_trt = combined_colspan_trt ) { - ### !!!! Map dataframe should not contain more tests than in data - ### as we need to split by PARCAT3, need to have a function for lty with the appropriate PARCAT3 selection - ### filter of the data, original factor levels can remain, no need to drop these levels - - tblidx <- get_tblid(tblid, PARCAT3sel) - titles2 <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" - ) - - lyt_filter <- function(PARCAT3sel = NULL, map) { - if (!is.null(PARCAT3sel)) { - map <- map %>% - filter(PARCAT3 %in% PARCAT3sel) - } - - lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by( - .trtvar - # , split_fun = add_combo_levels(combodf) - ) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - .trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels(.ctrl_grp) - ) %>% - split_rows_by( - "PARAMCD", - split_label = "Laboratory Test", - label_pos = "topleft", - child_labels = "hidden", - split_fun = trim_levels_to_map(map) - ) %>% - # Low prior to High - split_rows_by( - "CRITDIR", - label_pos = "hidden", - child_labels = "hidden", - split_fun = trim_levels_to_map(map) - ) %>% - split_rows_by( - "MCRIT12", - split_label = "Threshold Level, n (%)", - label_pos = "topleft", - split_fun = trim_levels_to_map(map), - section_div = " " - ) %>% - # denominators are varying per test, therefor show denom (not yet in shell) - analyze( - c("MCRIT12ML"), - a_freq_j, - extra_args = append(extra_args_rr, NULL), - show_labels = "hidden", - indent_mod = 0L - ) + if (!is.null(PARCAT1sel)) { + map <- map |> filter(toupper(PARCAT1) %in% toupper(PARCAT1sel)) + df <- df |> filter(toupper(PARCAT1) %in% toupper(PARCAT1sel)) } - lyt <- lyt_filter(PARCAT3sel = PARCAT3sel, map = map) - - if (!is.null(PARCAT3sel)) { - df <- df %>% - filter(PARCAT3 %in% PARCAT3sel) + if (nrow(df) == 0) { + message(paste0("PARCAT1 [", PARCAT1sel, "] is not present on input dataset")) + return(NULL) } - if (nrow(df) > 0) { - result <- build_table(lyt, df, alt_counts_df = .adsl) + lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + + if (.combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(.trtvar, split_fun = mysplit) } else { - result <- NULL - message(paste0( - "Parcat3 [", - PARCAT3sel, - "] is not present on input dataset" - )) - return(result) + lyt <- lyt |> split_cols_by(.trtvar) } + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + .trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels(.ctrl_grp) + ) |> + split_rows_by( + "PARAMCD", + split_label = "Laboratory Test", + label_pos = "topleft", + child_labels = "hidden", + split_fun = trim_levels_to_map(map) + ) |> + # Low prior to High + split_rows_by( + "CRITDIR", + label_pos = "hidden", + child_labels = "hidden", + split_fun = trim_levels_to_map(map) + ) |> + split_rows_by( + "MCRIT12", + split_label = "Threshold Level, n (%)", + label_pos = "topleft", + split_fun = trim_levels_to_map(map), + section_div = " " + ) |> + # denominators are varying per test, therefor show denom (not yet in shell) + analyze( + c("MCRIT12ML"), + a_freq_j, + extra_args = append(extra_args_rr, NULL), + show_labels = "hidden", + indent_mod = 0L + ) + + result <- build_table(lyt, df, alt_counts_df = .adsl, round_type = "sas") + ################################################################################ - # Remove Level 0 line + # Post-Processing: ################################################################################ - remove_grade0 <- function(tr) { if (is(tr, "DataRow") & (tr@label == "Level 0")) { return(FALSE) @@ -511,81 +400,31 @@ build_result_parcat3 <- function( } } - result <- result %>% prune_table(prune_func = keep_rows(remove_grade0)) - - ################################################################################ - # Remove unwanted column counts - ################################################################################ - + result <- result |> prune_table(prune_func = keep_rows(remove_grade0)) result <- remove_col_count(result) ################################################################################ - # Set title + # Add titles and footnotes: ################################################################################ - - result <- set_titles(result, titles2) - - if (save2rtf) { - ################################################################################ - # Convert to tbl file and output table - ################################################################################ - ### add the proper abbreviation to the tblid, and add opath path - fileid <- write_path(opath, tblidx) - - tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") - } + result <- set_titles(result, tab_titles) return(result) } - ################################################################################ -# Apply core function to all specified levels of parcat3 selection -# - General Chemistry (GC) -# - Kidney Function (KF) -# - Liver Biochemistry (LV) -# - Lipids (LP) -# - Hematology (HM) : -# Complete Blood Count -# WBC Differential -# Coagulation Studies +# Define layout and build table: ################################################################################ -### note : the same core tblid (TSFLAB02) will be used for all, inside the core function build_result_parcat3 the proper abbreviation will be added - -### titles will not be retrieved for these, as the table identifiers are not in the DPS system -### study teams will have to ensure all versions that are needed are included in DPS system -# result1 <- build_result_parcat3( -# PARCAT3sel = "Liver biochemistry", -# tblid = tblid, -# save2rtf = TRUE -# ) -# result2 <- build_result_parcat3( -# PARCAT3sel = "Kidney function", -# tblid = tblid, -# save2rtf = TRUE -# ) -# result3 <- build_result_parcat3( -# PARCAT3sel = "Lipids", -# tblid = tblid, -# save2rtf = TRUE -# ) -# -# result4 <- build_result_parcat3( -# PARCAT3sel = c( -# "Complete blood count", -# "WBC differential", -# "Coagulation studies" -# ), -# tblid = tblid, -# save2rtf = TRUE -# ) - -### if a certain category is not present, no rtf will be generated - -result <- build_result_parcat3(PARCAT3sel = "General chemistry", tblid = tblid, save2rtf = FALSE) - - -colwidth <- c(45, 21, 21, 21, 30, 30) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +result <- build_result_parcat1( + PARCAT1sel = parcat1_categories[["hem"]], + tblid = tblid +) + +colwidth <- c(42, 19, 19, 21, 21, 33, 35) + +tt_to_tlgrtf( + colwidths = colwidth, + result, + file = fileid, + orientation = "landscape" +) diff --git a/tests/testthat/source_code/tsflab02a.R b/tests/testthat/source_code/tsflab02a.R deleted file mode 100644 index d51c01b2..00000000 --- a/tests/testthat/source_code/tsflab02a.R +++ /dev/null @@ -1,642 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab02a -## R version: 4.2.1 -## Short Description: Program to create tsflab02a: Subjects With ≥1 [Laboratory Category] -## Laboratory Values With Elevated or Low Values -## Meeting Specified Levels Based on Worst On-treatment Value -## by [Subgroup] -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab02a.rtf -## Multiple tables are generated using this script -## These tables should be defined in Autocode (or titles file) as separate tables -## -tsflab02agc General chemistry -## -tsflab02akf Kidney function -## -tsflab02alv Liver biochemistry -## -tsflab02alp Lipids -## -tsflab02ahm Hematology - -## Remarks: Should only be used when abnormalities are based upon markedly abnormal file -## carefully review factor levels of variables MCRIT1/MCRIT2 and MCRIT1ML/MCRIT2ML on your input adlb.rds dataset -## Pay special attention to the following tests: -## Especially check if N is correct (review ADaM derivation for these params) -## GLUC : Glucose, high : LBFAST is part of condition -## HDL : separate levels for male/female -## HGB : separate levels for male/female -## -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFLAB02a" -fileid <- write_path(opath, tblid) -titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -popfl <- "SAFFL" -trtvar <- "TRT01A" -ctrl_grp <- "Placebo" - -subgrpvar <- "AGEGR1" -subgrplbl <- "Age: %s years" - -page_by <- TRUE # Set page_by TRUE/FALSE if you (do not) wish to start a new page after a new subgroup -indent_adj <- -1L -if (page_by) { - indent_adj <- 0L -} - -### note : this shell covers multiple tables depending on parcat3 selections - -## allowed PARCAT3 selections - -# parcat3sel <- "General chemistry" -# parcat3sel <- "Kidney function" -# parcat3sel <- "Liver biochemistry" -# parcat3sel <- "Lipids" -# -# ### Hematology (HM) : has 3 subcategories that should be included on one table -# parcat3sel <- c("Complete blood count","WBC differential","Coagulation studies") - -# per DPS specifications, the output identifier should include the abbreviation for the category - -# 1. Present laboratory tests using separate outputs for each category as follows: -# General chemistry (GC): Sodium, Potassium, Chloride, Bicarbonate, Urea Nitrogen, Glucose, Calcium, Magnesium, Phosphate, Protein, Albumin, Creatine Kinase, Amylase, Lipase -# Kidney function (KF): Creatinine, GFR from Creatinine -# Liver biochemistry (LV): Alkaline Phosphatase, Alanine Aminotransferase, Aspartate Aminotransferase, Bilirubin, Prothrombin Intl. Normalized Ratio, Gamma Glutamyl Transferase -# Lipids (LP): Cholesterol, HDL Cholesterol, LDL Cholesterol, Triglycerides -# Hematology (HM): Subcategory rows should be included for Complete Blood Count, White Blood Cell Differential and for Coagulation Studies -# Complete blood count: Leukocytes, Hemoglobin, Platelets; -# WBC differential: Lymphocytes, Neutrophils, Eosinophils; -# Coagulation studies: Prothrombin Time, Activated Partial Thromboplastin Time. - -# The output identifier should include the abbreviation for the laboratory category (eg, TSFLAB02GC for General Chemistry) - -# In current template program, only 1 version is created, without the proper abbreviation appended -# The reason for this is that TSFLAB02GC is not included in the DPS system - only the core version TSFLAB02 - -get_abbreviation <- function(parcat3sel) { - parcat3sel <- toupper(parcat3sel) - abbr <- NULL - if (length(parcat3sel) == 1) { - if (parcat3sel == toupper("General chemistry")) { - abbr <- "GC" - } - # the line below should be removed for a true study, global jjcs standards in DPS system does not include the abbreviation - if (parcat3sel == toupper("General chemistry")) { - abbr <- "" - } - # - if (parcat3sel == toupper("Kidney function")) { - abbr <- "KF" - } - if (parcat3sel == toupper("Liver biochemistry")) { - abbr <- "LV" - } - if (parcat3sel == toupper("Lipids")) abbr <- "LP" - } - if (length(parcat3sel) > 1) { - if ( - all( - parcat3sel %in% - toupper(c( - "Complete blood count", - "WBC differential", - "Coagulation studies" - )) - ) - ) { - abbr <- "HM" - } - } - - if (is.null(abbr)) { - message("Incorrect specification of parcat3sel") - } - - abbr -} - -get_tblid <- function(tblid, parcat3sel, method = c("after", "inbetween")) { - abbr <- get_abbreviation(parcat3sel) - - method <- match.arg(method) - # when inbetween, the abbreviation will be added prior to the number part of the table identifier - # when after (default), the abbreviation will be added at the end of the table identifier - - x <- 0 - if (method == "inbetween") { - x <- regexpr(pattern = "[0-9]", tblid)[1] - } - - if (x > 0) { - tblid1 <- substr(tblid, 1, x - 1) - tblid2 <- substring(tblid, x) - tblid_new <- paste0(tblid1, abbr, tblid2) - } else { - tblid_new <- paste0(tblid, abbr) - } - - return(tblid_new) -} - - -### the varying fileid will be handled at the end of the program, as this program will generate all levels -ad_domain <- "adlb" - - -## if the option TRTEMFL needs to be added to the TLF -- ensure the same setting as in tsflab04 -trtemfl <- TRUE - -################################################################################ -# Initial processing of data + check if table is valid for trial: -################################################################################ -adlb_complete <- adlb_jnj - - -################################################################################ -# Process markedly abnormal values from spreadsheet: -################################################################################ - -### Markedly Abnormal spreadsheet - -markedlyabnormal_file <- file.path(datapath, "markedlyabnormal.xlsx") - - - -lbmarkedlyabnormal_defs <- readxl::read_excel( - markedlyabnormal_file, - sheet = toupper(ad_domain) -) %>% - filter(PARAMCD != "Parameter Code") - -MCRITs <- unique( - lbmarkedlyabnormal_defs %>% - filter(!stringr::str_ends(VARNAME, "ML")) %>% - pull(VARNAME) -) - -MCRITs_def <- unique( - lbmarkedlyabnormal_defs %>% - filter(VARNAME %in% MCRITs) %>% - select(PARAMCD, VARNAME, CRIT, SEX) -) %>% - mutate(VARNAME = paste0(VARNAME, "ML")) %>% - rename(CRITNAME = CRIT) %>% - mutate( - CRITDIR = case_when( - VARNAME == "MCRIT1ML" ~ "DIR1", - VARNAME == "MCRIT2ML" ~ "DIR2" - ) - ) - - -MCRITs_def2 <- lbmarkedlyabnormal_defs %>% - filter(VARNAME %in% paste0(MCRITs, "ML")) %>% - mutate(CRITn = as.character(4 - as.numeric(ORDER))) - - -MCRITs_def3 <- MCRITs_def2 %>% - left_join(., MCRITs_def, relationship = "many-to-one") %>% - select(PARAMCD, CRITNAME, CRITDIR, SEX, VARNAME, CRIT, CRITn) %>% - arrange(PARAMCD, VARNAME, CRITDIR, SEX, CRITn) %>% - select(-SEX) - - -### convert dataframe into label_map that can be used with the a_freq_j afun function -xlabel_map <- MCRITs_def3 %>% - rename(var = VARNAME, label = CRIT) %>% - select(PARAMCD, CRITNAME, CRITDIR, var, label) - - -xlabel_map2 <- xlabel_map %>% - mutate( - MCRIT12 = CRITNAME, - MCRIT12ML = label - ) - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select(USUBJID, all_of(c(popfl, trtvar, subgrpvar))) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -adsl$rrisk_header <- "Risk Difference (%) (95% CI)" -adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - - -obs_mcrit12 <- unique(c( - unique(adlb_complete$MCRIT1), - unique(adlb_complete$MCRIT2) -)) - -adlb00 <- adlb_complete %>% - filter(PARCAT2 == "Test with FDA abnormality criteria defined") %>% - select( - USUBJID, - PARCAT1, - PARCAT2, - PARCAT3, - ONTRTFL, - TRTEMFL, - PARAM, - PARAMCD, - AVISITN, - AVISIT, - AVAL, - MCRIT1, - MCRIT1ML, - MCRIT2, - MCRIT2ML, - ONTRTFL, - TRTEMFL, - LVOTFL, - ANL01FL, - ANL02FL, - ANL04FL, - ANL05FL - ### if per period/phase is needed, use below flag variables - # ,ANL07FL,ANL08FL,ANL09FL,ANL10FL - ) %>% - inner_join(adsl) - - -combodf <- tribble( - ~valname, ~label, ~levelcombo, ~exargs, - "xan-comb", "Xanomeline Combined", c("Xanomeline High Dose", "Xanomeline Low Dose"), list() -) - -################################################################################ -##### vertical approach for analyzing MCRIT1/MCRIT2: -# filtering is easier, as well as the analyze/layout setup -################################################################################ - -adlb_mcrit1 <- adlb00 %>% - filter(!is.na(MCRIT1)) %>% - mutate( - MCRIT12 = MCRIT1, - MCRIT12ML = MCRIT1ML, - CRITDIR = "DIR1", - ANL045FL = ANL04FL - ) - -adlb_mcrit2 <- adlb00 %>% - filter(!is.na(MCRIT2)) %>% - mutate( - MCRIT12 = MCRIT2, - MCRIT12ML = MCRIT2ML, - CRITDIR = "DIR2", - ANL045FL = ANL05FL - ) - -### note: by filter ANL04FL/ANL05FL, this table is restricted to On-treatment values, per definition of ANL04FL/ANL05FL -### therefor, no need to add ONTRTFL in filter -### if derivation of ANL04FL/ANL05FL is not restricted to ONTRTFL records, adding ONTRTFL here will not give the correct answer either -### as mixing worst with other period is not giving the proper selection !!! -adlb_mcrit <- rbind(adlb_mcrit1, adlb_mcrit2) %>% - filter(ANL045FL == "Y") %>% - inner_join(., adsl) - -#### DO NOT USE TRTEMFL = Y in filter, as this will remove subjects from both numerator and denominator -#### instead : set MCRIT12ML to a non-reportable value (ie Level 0) and keep in dataset -if (trtemfl) { - origlevs <- levels(adlb_mcrit$MCRIT12ML) - - adlb_mcrit <- adlb_mcrit %>% - mutate( - MCRIT12ML = case_when( - !is.na(MCRIT12ML) & is.na(TRTEMFL) | TRTEMFL != "Y" ~ "Level 0", - TRUE ~ MCRIT12ML - ) - ) %>% - mutate(MCRIT12ML = factor(MCRIT12ML, levels = origlevs)) -} - -################################################################################ -##### finalize mapping dataframe based upon abnormal spreadsheet -################################################################################ - -xlabel_map3 <- xlabel_map2 %>% - right_join(., unique(adlb_mcrit %>% select(PARAMCD, PARCAT3))) %>% - arrange(PARCAT3, PARAMCD, CRITDIR, MCRIT12, MCRIT12ML) %>% - mutate_if(is.factor, as.character) %>% - #### get rid of mapping defined in spreadsheet but not present in data - filter(MCRIT12 %in% obs_mcrit12) - -### this will ensure alphabetical sorting on abnormality -### within a test LOW needs to come prior to High -### for this reason, split a test like 'Calcium, low' and 'Calcium, High' in 2 -xlabel_map3 <- xlabel_map3 %>% - mutate(MCRIT12x = stringr::str_split_i(MCRIT12, ",", 1)) %>% - arrange(MCRIT12x, CRITDIR, MCRIT12ML) - - -# MCRIT12ML needs to be a factor, with all levels (also unobserved), -# as these levels are not available on the metadata files, only in markedly abnormal -# we need to update the factor levels -# these are present in the markedly abnormal file processing, ie we can use xlabel_map3 -adlb_mcrit$MCRIT12ML <- factor( - as.character(adlb_mcrit$MCRIT12ML), - levels = unique(xlabel_map3$MCRIT12ML) -) - - -################################################################################ -# Define layout and build table: -################################################################################ - -################################################################################ -# Core function to produce shell for specific parcat3 selection -################################################################################ -build_result_parcat3 <- function( - df = adlb_mcrit, - PARCAT3sel = NULL, - .adsl = adsl, - map = xlabel_map3, - tblid, - save2rtf = TRUE, - subgroup = NULL, - label_fstr = NULL, - .trtvar = trtvar, - .ctrl_grp = ctrl_grp, - .ref_path = ref_path, - .page_by = page_by, - .indent_adj = indent_adj -) { - tblidx <- get_tblid(tblid, PARCAT3sel) - titles2 <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" - ) - - .extra_args_rr <- list( - method = "wald", - denom = "n_df", - ref_path = .ref_path, - .stats = c("denom", "count_unique_fraction"), - denom_by = subgroup - ) - - .extra_args_rr2 <- list( - denom = "n_altdf", - denom_by = subgroup, - riskdiff = FALSE, - extrablankline = TRUE, - .stats = c("n_altdf"), - label_fstr = label_fstr - ) - - ### !!!! Map dataframe should not contain more tests than in data - ### as we need to split by PARCAT3, need to have a function for lty with the appropriate PARCAT3 selection - ### filter of the data, original factor levels can remain, no need to drop these levels - - lyt_filter <- function( - PARCAT3sel = NULL, - map, - subgroup = NULL, - label_fstr = NULL - ) { - if (!is.null(PARCAT3sel)) { - map <- map %>% - filter(PARCAT3 %in% PARCAT3sel) - } - - lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by( - .trtvar - # , split_fun = add_combo_levels(combodf) - ) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - .trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels(.ctrl_grp) - ) - - if (!is.null(subgroup)) { - lyt <- lyt %>% - split_rows_by( - subgroup, - label_pos = "hidden", - section_div = " ", - split_fun = drop_split_levels, - page_by = .page_by - ) %>% - ### - summarize_row_groups( - var = subgroup, - cfun = a_freq_j, - extra_args = .extra_args_rr2 - ) - } - - lyt <- lyt %>% - split_rows_by( - "PARAMCD", - split_label = "Laboratory Test", - label_pos = "topleft", - child_labels = "hidden", - split_fun = trim_levels_to_map(map), - indent_mod = .indent_adj - ) %>% - ## Low prior to High - split_rows_by( - "CRITDIR", - label_pos = "hidden", - child_labels = "hidden", - split_fun = trim_levels_to_map(map) - ) %>% - split_rows_by( - "MCRIT12", - split_label = "Threshold Level, n (%)", - label_pos = "topleft", - split_fun = trim_levels_to_map(map), - section_div = " " - ) %>% - # denominators are varying per test, therefor show denom (not yet in shell) - analyze( - c("MCRIT12ML"), - a_freq_j, - extra_args = append(.extra_args_rr, NULL), - show_labels = "hidden", - indent_mod = 0L - ) - - return(lyt) - } - - lyt <- lyt_filter( - PARCAT3sel = PARCAT3sel, - map = map, - subgroup = subgroup, - label_fstr = label_fstr - ) - - if (!is.null(PARCAT3sel)) { - df <- df %>% - filter(PARCAT3 %in% PARCAT3sel) - } - - if (nrow(df) > 0) { - result <- build_table(lyt, df, alt_counts_df = .adsl) - } else { - result <- NULL - message(paste0( - "Parcat3 [", - PARCAT3sel, - "] is not present on input dataset" - )) - return(result) - } - - ################################################################################ - # Remove Level 0 line - ################################################################################ - - remove_grade0 <- function(tr) { - if (is(tr, "DataRow") & (tr@label == "Level 0")) { - return(FALSE) - } else if (is(tr, "DataRow") & (tr@label == no_data_to_report_str)) { - return(FALSE) - } else { - return(TRUE) - } - } - - result <- result %>% prune_table(prune_func = keep_rows(remove_grade0)) - - ################################################################################ - # Remove unwanted column counts - ################################################################################ - - result <- remove_col_count(result) - ################################################################################ - # Set title - ################################################################################ - - result <- set_titles(result, titles2) - - if (save2rtf) { - ################################################################################ - # Convert to tbl file and output table - ################################################################################ - ### add the proper abbreviation to the tblid, and add opath path - fileid <- write_path(opath, tblidx) - - tt_to_tlgrtf(result, file = fileid, orientation = "landscape") - } - - return(result) -} - - -################################################################################ -# Apply core function to all specified levels of parcat3 selection -# - General Chemistry (GC) -# - Kidney Function (KF) -# - Liver Biochemistry (LV) -# - Lipids (LP) -# - Hematology (HM) : -# Complete Blood Count -# WBC Differential -# Coagulation Studies -################################################################################ - -### note : the same core tblid (TSFLAB02a) will be used for all, inside the core function build_result_parcat3 the proper abbreviation will be added - -### titles will not be retrieved for these, as the table identifiers are not in the DPS system -### study teams will have to ensure all versions that are needed are included in DPS system -# result1 <- build_result_parcat3( -# PARCAT3sel = "Liver biochemistry", -# tblid = tblid, -# subgroup = subgrpvar, -# label_fstr = subgrplbl, -# save2rtf = TRUE -# ) -# result2 <- build_result_parcat3( -# PARCAT3sel = "Kidney function", -# tblid = tblid, -# subgroup = subgrpvar, -# label_fstr = subgrplbl, -# save2rtf = TRUE -# ) -# result3 <- build_result_parcat3( -# PARCAT3sel = "Lipids", -# tblid = tblid, -# subgroup = subgrpvar, -# label_fstr = subgrplbl, -# save2rtf = TRUE -# ) -# -# -# result4 <- build_result_parcat3( -# PARCAT3sel = c( -# "Complete blood count", -# "WBC differential", -# "Coagulation studies" -# ), -# tblid = tblid, -# subgroup = subgrpvar, -# label_fstr = subgrplbl, -# save2rtf = TRUE -# ) - -### if a certain category is not present, no rtf will be generated - -result <- build_result_parcat3( - PARCAT3sel = "General chemistry", - tblid = tblid, - subgroup = subgrpvar, - label_fstr = subgrplbl, - save2rtf = FALSE -) - -colwidth <- c(47, 21, 21, 19, 35, 35) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab02b.R b/tests/testthat/source_code/tsflab02b.R index d3e10040..65ae8585 100644 --- a/tests/testthat/source_code/tsflab02b.R +++ b/tests/testthat/source_code/tsflab02b.R @@ -1,39 +1,4 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab02b -## R version: 4.2.1 -## Short Description: Program to create tsflab02b: Subjects With -## [Laboratory Category] Laboratory Abnormalities Over Time -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab02b.rtf -## Multiple tables are generated using this script -## These tables should be defined in Autocode (or titles file) as separate tables -## -tsflab02bgc General chemistry -## -tsflab02bkf Kidney function -## -tsflab02blv Liver biochemistry -## -tsflab02blp Lipids -## -tsflab02bhm Hematology -## -## Remarks: Should only be used when abnormalities are based upon markedly abnormal file -## carefully review factor levels of variables MCRIT1/MCRIT2 and MCRIT1ML/MCRIT2ML on your input adlb.rds dataset -## Pay special attention to the following tests: -## Especially check if N is correct (review ADaM derivation for these params) -## GLUC : Glucose, high : LBFAST is part of condition -## HDL : separate levels for male/female -## HGB : separate levels for male/female -## Pay special attention to the following tests: -## -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - +#### BEFORE YOU START USING THIS PROGRAM ENSURE THE FOLLOWING: For your trial you should EITHER use lab toxicity grading (lbtoxgrade file) or Abnormality criteria (markedly abnormal file) ################################################################################ # Prep Environment ################################################################################ @@ -49,120 +14,49 @@ library(junco) ################################################################################ tblid <- "TSFLAB02b" -fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) +# Population flag variable (default=SAFFL). popfl <- "SAFFL" +# Actual treatment variable (default=TRT01A). trtvar <- "TRT01A" -ctrl_grp <- "Placebo" -### note : this shell covers multiple tables depending on parcat3 selections - -## allowed PARCAT3 selections - -# parcat3sel <- "General chemistry" -# parcat3sel <- "Kidney function" -# parcat3sel <- "Liver biochemistry" -# parcat3sel <- "Lipids" -# -# ### Hematology (HM) : has 3 subcategories that should be included on one table -# parcat3sel <- c("Complete blood count","WBC differential","Coagulation studies") - -# per DPS specifications, the output identifier should include the abbreviation for the category - -# 1. Present laboratory tests using separate outputs for each category as follows: -# General chemistry (GC): Sodium, Potassium, Chloride, Bicarbonate, Urea Nitrogen, Glucose, Calcium, Magnesium, Phosphate, Protein, Albumin, Creatine Kinase, Amylase, Lipase -# Kidney function (KF): Creatinine, GFR from Creatinine -# Liver biochemistry (LV): Alkaline Phosphatase, Alanine Aminotransferase, Aspartate Aminotransferase, Bilirubin, Prothrombin Intl. Normalized Ratio, Gamma Glutamyl Transferase -# Lipids (LP): Cholesterol, HDL Cholesterol, LDL Cholesterol, Triglycerides -# Hematology (HM): Subcategory rows should be included for Complete Blood Count, White Blood Cell Differential and for Coagulation Studies -# Complete blood count: Leukocytes, Hemoglobin, Platelets; -# WBC differential: Lymphocytes, Neutrophils, Eosinophils; -# Coagulation studies: Prothrombin Time, Activated Partial Thromboplastin Time. - -# The output identifier should include the abbreviation for the laboratory category (eg, TSFLAB02GC for General Chemistry) - -# In current template program, only 1 version is created, without the proper abbreviation appended -# The reason for this is that TSFLAB02GC is not included in the DPS system - only the core version TSFLAB02 - -get_abbreviation <- function(parcat3sel) { - parcat3sel <- toupper(parcat3sel) - abbr <- NULL - if (length(parcat3sel) == 1) { - if (parcat3sel == toupper("General chemistry")) { - abbr <- "GC" - } - # the following line should be removed for a true study, global jjcs standards in DPS system does not include the abbreviation - if (parcat3sel == toupper("General chemistry")) { - abbr <- "" - } - # - if (parcat3sel == toupper("Kidney function")) { - abbr <- "KF" - } - if (parcat3sel == toupper("Liver biochemistry")) { - abbr <- "LV" - } - if (parcat3sel == toupper("Lipids")) abbr <- "LP" - } - if (length(parcat3sel) > 1) { - if ( - all( - parcat3sel %in% - toupper(c( - "Complete blood count", - "WBC differential", - "Coagulation studies" - )) - ) - ) { - abbr <- "HM" - } - } - - if (is.null(abbr)) { - message("Incorrect specification of parcat3sel") - } - - abbr -} - -get_tblid <- function(tblid, parcat3sel, method = c("after", "inbetween")) { - abbr <- get_abbreviation(parcat3sel) +ctrl_grp <- "Placebo" - method <- match.arg(method) - # when inbetween, the abbreviation will be added prior to the number part of the table identifier - # when after (default), the abbreviation will be added at the end of the table identifier +# Add Active Study Agent Combined column +combined_colspan_trt <- TRUE - x <- 0 - if (method == "inbetween") { - x <- regexpr(pattern = "[0-9]", tblid)[1] - } +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) - if (x > 0) { - tblid1 <- substr(tblid, 1, x - 1) - tblid2 <- substring(tblid, x) - tblid_new <- paste0(tblid1, abbr, tblid2) - } else { - tblid_new <- paste0(tblid, abbr) - } + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) - return(tblid_new) + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) } - -### the varying fileid will be handled at the end of the program, as this program will generate all levels +# PARCAT1 categories to produce: CHEMISTRY -> CHM, HEMATOLOGY -> HM +parcat1_categories <- list( + chm = "CHEMISTRY", + hem = "HEMATOLOGY" +) ad_domain <- "adlb" - selvisit <- c("Screening", "Cycle 02", "Cycle 03", "Cycle 04") -## if the option TRTEMFL needs to be added to the TLF -- ensure the same setting as in tsflab04 -trtemfl <- TRUE + ################################################################################ # Initial processing of data + check if table is valid for trial: @@ -170,35 +64,36 @@ trtemfl <- TRUE adlb_complete <- adlb_jnj + ################################################################################ # Process markedly abnormal values from spreadsheet: ################################################################################ ### Markedly Abnormal spreadsheet -markedlyabnormal_file <- file.path(datapath, "markedlyabnormal.xlsx") - +markedlyabnormal_file <- read_path(datapath, "markedlyabnormal.xlsx") +markedlyabnormal_sheets <- readxl::excel_sheets(markedlyabnormal_file) lbmarkedlyabnormal_defs <- readxl::read_excel( markedlyabnormal_file, sheet = toupper(ad_domain) -) %>% +) |> filter(PARAMCD != "Parameter Code") MCRITs <- unique( - lbmarkedlyabnormal_defs %>% - filter(!stringr::str_ends(VARNAME, "ML")) %>% + lbmarkedlyabnormal_defs |> + filter(!stringr::str_ends(VARNAME, "ML")) |> pull(VARNAME) ) MCRITs_def <- unique( - lbmarkedlyabnormal_defs %>% - filter(VARNAME %in% MCRITs) %>% + lbmarkedlyabnormal_defs |> + filter(VARNAME %in% MCRITs) |> select(PARAMCD, VARNAME, CRIT, SEX) -) %>% - mutate(VARNAME = paste0(VARNAME, "ML")) %>% - rename(CRITNAME = CRIT) %>% +) |> + mutate(VARNAME = paste0(VARNAME, "ML")) |> + rename(CRITNAME = CRIT) |> mutate( CRITDIR = case_when( VARNAME == "MCRIT1ML" ~ "DIR1", @@ -207,22 +102,22 @@ MCRITs_def <- unique( ) -MCRITs_def2 <- lbmarkedlyabnormal_defs %>% - filter(VARNAME %in% paste0(MCRITs, "ML")) %>% +MCRITs_def2 <- lbmarkedlyabnormal_defs |> + filter(VARNAME %in% paste0(MCRITs, "ML")) |> mutate(CRITn = as.character(4 - as.numeric(ORDER))) -MCRITs_def3 <- MCRITs_def2 %>% - left_join(., MCRITs_def, relationship = "many-to-one") %>% - select(PARAMCD, CRITNAME, CRITDIR, SEX, VARNAME, CRIT, CRITn) %>% - arrange(PARAMCD, VARNAME, CRITDIR, SEX, CRITn) %>% +MCRITs_def3 <- MCRITs_def2 |> + left_join(MCRITs_def, relationship = "many-to-one") |> + select(PARAMCD, CRITNAME, CRITDIR, SEX, VARNAME, CRIT, CRITn) |> + arrange(PARAMCD, VARNAME, CRITDIR, SEX, CRITn) |> select(-SEX) ### convert dataframe into label_map that can be used with the a_freq_j afun function -xlabel_map <- MCRITs_def3 %>% - rename(var = VARNAME, label = CRIT) %>% +xlabel_map <- MCRITs_def3 |> + rename(var = VARNAME, label = CRIT) |> select(PARAMCD, CRITNAME, CRITDIR, var, label) -xlabel_map2 <- xlabel_map %>% +xlabel_map2 <- xlabel_map |> mutate( MCRIT12 = CRITNAME, MCRIT12ML = label @@ -232,8 +127,14 @@ xlabel_map2 <- xlabel_map %>% # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> select(USUBJID, all_of(c(popfl, trtvar))) adsl$colspan_trt <- factor( @@ -259,15 +160,15 @@ obs_mcrit12 <- unique(c( unique(adlb_complete$MCRIT2) )) -adlb00 <- adlb_complete %>% - filter(PARCAT2 == "Test with FDA abnormality criteria defined") %>% +adlb00 <- adlb_complete |> + filter(!is.na(PARCAT2)) |> select( USUBJID, PARCAT1, PARCAT2, PARCAT3, + PARCAT3N, ONTRTFL, - TRTEMFL, PARAM, PARAMCD, AVISITN, @@ -277,8 +178,6 @@ adlb00 <- adlb_complete %>% MCRIT1ML, MCRIT2, MCRIT2ML, - ONTRTFL, - TRTEMFL, LVOTFL, ABLFL, ANL01FL, @@ -287,78 +186,59 @@ adlb00 <- adlb_complete %>% ANL05FL ### if per period/phase is needed, use below flag variables # ,ANL07FL,ANL08FL,ANL09FL,ANL10FL - ) %>% + ) |> inner_join(adsl) - -combodf <- tribble( - ~valname, ~label, ~levelcombo, ~exargs, - "xan-comb", "Xanomeline Combined", c("Xanomeline High Dose", "Xanomeline Low Dose"), list() -) - ################################################################################ ##### vertical approach for analyzing MCRIT1/MCRIT2: # filtering is easier, as well as the analyze/layout setup ################################################################################ -adlb_mcrit1 <- adlb00 %>% - filter(!is.na(MCRIT1)) %>% +adlb_mcrit1 <- adlb00 |> + filter(!is.na(MCRIT1)) |> mutate( MCRIT12 = MCRIT1, MCRIT12ML = MCRIT1ML, CRITDIR = "DIR1" ) -adlb_mcrit2 <- adlb00 %>% - filter(!is.na(MCRIT2)) %>% +adlb_mcrit2 <- adlb00 |> + filter(!is.na(MCRIT2)) |> mutate( MCRIT12 = MCRIT2, MCRIT12ML = MCRIT2ML, CRITDIR = "DIR2" ) -adlb_mcrit <- rbind(adlb_mcrit1, adlb_mcrit2) %>% - mutate(CRITDIR = factor(CRITDIR)) %>% - filter(AVISIT %in% selvisit) %>% +adlb_mcrit <- rbind(adlb_mcrit1, adlb_mcrit2) |> + mutate( + CRITDIR = factor(CRITDIR), + PARAMCD := ordered(PARAMCD, levels = { + # Sort by PARCAT3N then PARAMCD and PARCAT3 not displayed used only for sorting + unique(PARAMCD[order(PARCAT3N, PARAM)]) + }) + ) |> + filter(AVISIT %in% selvisit) |> ### unique record per timepoint: - filter(ANL02FL == "Y") %>% - # ### Restrict to On-treatment / not clear??? - # To be in line with Other over time tables - we do NOT filter on ONTRTFL - awaiting confirmation - # filter(ONTRTFL == "Y" | ABLFL == "Y") %>% - - inner_join(., adsl) - -#### DO NOT USE TRTEMFL = Y in filter, as this will remove subjects from both numerator and denominator -#### instead : set MCRIT12ML to a non-reportable value (ie Level 0) and keep in dataset -if (trtemfl) { - origlevs <- levels(adlb_mcrit$MCRIT12ML) - adlb_mcrit <- adlb_mcrit %>% - mutate( - MCRIT12ML = case_when( - !is.na(MCRIT12ML) & is.na(TRTEMFL) | TRTEMFL != "Y" ~ "Level 0", - TRUE ~ MCRIT12ML - ) - ) %>% - mutate(MCRIT12ML = factor(MCRIT12ML, levels = origlevs)) -} + filter(ANL02FL == "Y") ################################################################################ ##### finalize mapping dataframe based upon abnormal spreadsheet ################################################################################ -xlabel_map3 <- xlabel_map2 %>% - right_join(., unique(adlb_mcrit %>% select(PARAMCD, PARCAT3))) %>% - arrange(PARCAT3, PARAMCD, CRITDIR, MCRIT12, MCRIT12ML) %>% - mutate_if(is.factor, as.character) %>% +xlabel_map3 <- xlabel_map2 |> + right_join(unique(adlb_mcrit |> select(PARAMCD, PARCAT1, PARCAT3N, PARCAT3))) |> + arrange(PARCAT1, PARCAT3N, PARAMCD, CRITDIR, MCRIT12, MCRIT12ML) |> + mutate_if(is.factor, as.character) |> #### get rid of mapping defined in spreadsheet but not present in data filter(MCRIT12 %in% obs_mcrit12) ### this will ensure alphabetical sorting on abnormality ### within a test LOW needs to come prior to High ### for this reason, split a test like 'Calcium, low' and 'Calcium, High' in 2 -xlabel_map3 <- xlabel_map3 %>% - mutate(MCRIT12x = stringr::str_split_i(MCRIT12, ",", 1)) %>% - arrange(MCRIT12x, CRITDIR, MCRIT12ML) +xlabel_map3 <- xlabel_map3 |> + mutate(MCRIT12x = stringr::str_split_i(MCRIT12, ",", 1)) |> + arrange(PARCAT1, PARCAT3N, MCRIT12x, CRITDIR, MCRIT12ML) # MCRIT12ML needs to be a factor, with all levels (also unobserved), # as these levels are not available on the metadata files, only in markedly abnormal @@ -369,6 +249,10 @@ adlb_mcrit$MCRIT12ML <- factor( levels = unique(xlabel_map3$MCRIT12ML) ) +adlb_mcrit$AVISIT <- factor( + adlb_mcrit$AVISIT, + levels = unique(adlb_mcrit$AVISIT)[order(unique(adlb_mcrit$AVISITN))] +) ################################################################################ # Define layout and build table: @@ -378,137 +262,133 @@ adlb_mcrit$MCRIT12ML <- factor( method = "wald", denom = "n_df", ref_path = ref_path, - .stats = c("count_unique_fraction") + .stats = c("count_unique_fraction"), + na_str = "-" ) ################################################################################ # Core function to produce shell for specific parcat3 selection ################################################################################ -build_result_parcat3 <- function( +build_result_parcat1 <- function( df = adlb_mcrit, - PARCAT3sel = NULL, + PARCAT1sel = NULL, + tblid, .adsl = adsl, map = xlabel_map3, - tblid, save2rtf = TRUE, extra_args_rr = .extra_args_rr, .trtvar = trtvar, .ref_path = ref_path, - .ctrl_grp = ctrl_grp + .ctrl_grp = ctrl_grp, + .combined_colspan_trt = combined_colspan_trt ) { - ### !!!! Map dataframe should not contain more tests than in data - ### as we need to split by PARCAT3, need to have a function for lty with the appropriate PARCAT3 selection - ### filter of the data, original factor levels can remain, no need to drop these levels - - tblidx <- get_tblid(tblid, PARCAT3sel) - titles2 <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" - ) - - lyt_filter <- function(PARCAT3sel = NULL, map) { - if (!is.null(PARCAT3sel)) { - map <- map %>% - filter(PARCAT3 %in% PARCAT3sel) + lyt_filter <- function(PARCAT1sel = NULL, map) { + if (!is.null(PARCAT1sel)) { + map <- map |> + filter(toupper(PARCAT1) %in% toupper(PARCAT1sel)) } - lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% + lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by( - .trtvar - # , split_fun = add_combo_levels(combodf) - ) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + ) + + if (.combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(.trtvar, split_fun = mysplit) + } else { + lyt <- lyt |> split_cols_by(.trtvar) + } + + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( .trtvar, labels_var = "rrisk_label", split_fun = remove_split_levels(.ctrl_grp) ) - ### add in by avisit processing - lyt <- lyt %>% - split_rows_by( - "AVISIT", - label_pos = "topleft", - section_div = " ", - split_fun = drop_split_levels, - split_label = "Time Point" - ) %>% - summarize_row_groups( - var = "AVISIT", - cfun = a_freq_j, - extra_args = list( - .stats = "n_df", - riskdiff = FALSE - ), - indent_mod = -1L - ) - lyt <- lyt %>% + lyt <- lyt |> split_rows_by( "PARAMCD", - split_label = "Laboratory Test", - label_pos = "topleft", - indent_mod = 1L, + label_pos = "hidden", child_labels = "hidden", + indent_mod = 1L, split_fun = trim_levels_to_map(map) - ) %>% + ) |> ## Low prior to High split_rows_by( "CRITDIR", label_pos = "hidden", child_labels = "hidden", split_fun = trim_levels_to_map(map) - ) %>% + ) |> split_rows_by( "MCRIT12", - split_label = "Threshold Level, n (%)", + split_label = "Laboratory Test", label_pos = "topleft", split_fun = trim_levels_to_map(map), - child_labels = "visible", + child_labels = "hidden", section_div = " " - ) %>% + ) |> + summarize_row_groups( + var = "MCRIT12", + cfun = a_freq_j, + extra_args = list( + .stats = "n_df", + riskdiff = FALSE + ), + indent_mod = -1L + ) + + ### add in by avisit processing + lyt <- lyt |> + split_rows_by( + "AVISIT", + label_pos = "topleft", + section_div = " ", + child_labels = "visible", + split_fun = drop_split_levels, + split_label = "Study Visit" + ) |> ### to mimic layout if analyze would be used instead ### child_labels has been set to visible in previous step summarize_row_groups( - "MCRIT12", + "AVISIT", cfun = a_freq_j, extra_args = list( .stats = "n_df", label = "N", riskdiff = FALSE ) - ) %>% + ) |> + append_topleft(" Threshold Level, n (%)") |> # denominators are varying per test, no need to show as N is shown in line above analyze( c("MCRIT12ML"), a_freq_j, extra_args = extra_args_rr, - show_labels = "hidden", - indent_mod = 1L + show_labels = "hidden" ) return(lyt) } - lyt <- lyt_filter(PARCAT3sel = PARCAT3sel, map = map) + lyt <- lyt_filter(PARCAT1sel = PARCAT1sel, map = map) - if (!is.null(PARCAT3sel)) { - df <- df %>% - filter(PARCAT3 %in% PARCAT3sel) + if (!is.null(PARCAT1sel)) { + df <- df |> + filter(toupper(PARCAT1) %in% toupper(PARCAT1sel)) } if (nrow(df) > 0) { - result <- build_table(lyt, df, alt_counts_df = .adsl) + result <- build_table(lyt, df, alt_counts_df = .adsl, round_type = "sas") } else { result <- NULL message(paste0( - "Parcat3 [", - PARCAT3sel, + "PARCAT1 [", + PARCAT1sel, "] is not present on input dataset" )) return(result) @@ -528,7 +408,7 @@ build_result_parcat3 <- function( } } - result <- result %>% prune_table(prune_func = keep_rows(remove_grade0)) + result <- result |> prune_table(prune_func = keep_rows(remove_grade0)) ################################################################################ # Remove unwanted column counts @@ -536,129 +416,32 @@ build_result_parcat3 <- function( result <- remove_col_count(result) - ################################################################################ - # Prune table to remove when n = 0 in all columns - ################################################################################ - ### alhtough this is not really likely to occur in real data, this is a problem in the current synthetic data - ### also here, try to remove this issue - - ### below code is based upon - ### 1. tern pruning function all_zero_or_na - ### 2. tern CombinationFunction - ### 3a. tern pruning function h_content_first_row - ### 3b. tern pruning function keep_content_rows - - ### 1. similar to tern pruning function all_zero_or_na - my_all_zero_or_na <- function(tr) { - # Main values are extracted - row_vals <- row_values(tr) - - if (!is(tr, "TableRow") || is(tr, "LabelRow")) { - return(FALSE) - } - rvs <- unlist(unname(row_vals)) - - ### last condition is different versus all_zero_or_na - all(is.na(rvs) | rvs == 0 | rvs == "") - } - - ### 2. tern CombinationFunction - is_non_empty <- !CombinationFunction(my_all_zero_or_na) - - ### 3a. similar to tern pruning function h_content_first_row - h_content_second_row <- function(table) { - ct <- content_table(table) - tree_children(ct)[[2]] - } - - ### 3b. based uupon tern pruning function keep_content_rows - my_keep_content_rows <- function(content_row_condition) { - checkmate::assert_function(content_row_condition) - function(table_tree) { - if (tern:::is_leaf_table(table_tree)) { - ### take second row from the content rather than first - content_row <- h_content_first_row(table_tree) - return(!content_row_condition(content_row)) - } - if (inherits(table_tree, "DataRow")) { - return(FALSE) - } - children <- tree_children(table_tree) - identical(length(children), 0L) - } - } - - result <- prune_table(result, my_keep_content_rows(is_non_empty)) - ################################################################################ # Set title ################################################################################ - result <- set_titles(result, titles2) - - if (save2rtf) { - ################################################################################ - # Convert to tbl file and output table - ################################################################################ - ### add the proper abbreviation to the tblid, and add opath path - fileid <- write_path(opath, tblidx) - - tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") - } + result <- set_titles(result, tab_titles) return(result) } + ################################################################################ -# Apply core function to all specified levels of parcat3 selection -# - General Chemistry (GC) -# - Kidney Function (KF) -# - Liver Biochemistry (LV) -# - Lipids (LP) -# - Hematology (HM) : -# Complete Blood Count -# WBC Differential -# Coagulation Studies +# Define layout and build table: ################################################################################ -### note : the same core tblid (TSFLAB02) will be used for all, inside the core function build_result_parcat3 the proper abbreviation will be added - -### titles will not be retrieved for these, as the table identifiers are not in the DPS system -### study teams will have to ensure all versions that are needed are included in DPS system -# result1 <- build_result_parcat3( -# PARCAT3sel = "Liver biochemistry", -# tblid = tblid, -# save2rtf = TRUE -# ) -# result2 <- build_result_parcat3( -# PARCAT3sel = "Kidney function", -# tblid = tblid, -# save2rtf = TRUE -# ) -# result3 <- build_result_parcat3( -# PARCAT3sel = "Lipids", -# tblid = tblid, -# save2rtf = TRUE -# ) -# -# result4 <- build_result_parcat3( -# PARCAT3sel = c( -# "Complete blood count", -# "WBC differential", -# "Coagulation studies" -# ), -# tblid = tblid, -# save2rtf = TRUE -# ) - -### if a certain category is not present, no rtf will be generated - -result <- build_result_parcat3( - PARCAT3sel = "General chemistry", - tblid = tblid, - save2rtf = FALSE +result <- build_result_parcat1( + PARCAT1sel = parcat1_categories[["hem"]], + tblid = tblid ) -colwidth <- c(49, 19, 19, 19, 33, 33) +colwidth <- c(44, 21, 21, 21, 21, 35, 35) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +fileid <- write_path(opath, tblid) + +tt_to_tlgrtf( + colwidths = colwidth, + result, + file = fileid, + orientation = "landscape" +) diff --git a/tests/testthat/source_code/tsflab02c.R b/tests/testthat/source_code/tsflab02c.R new file mode 100644 index 00000000..82e03970 --- /dev/null +++ b/tests/testthat/source_code/tsflab02c.R @@ -0,0 +1,369 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFLAB02c" +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +# Population flag variable (default=SAFFL). +popfl <- "SAFFL" +# Actual treatment variable (default=TRT01A). +trtvar <- "TRT01A" + +ctrl_grp <- "Placebo" + +# Add Active Study Agent Combined column +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +# PARCAT1 categories to produce: CHEMISTRY -> CHM, HEMATOLOGY -> HM +parcat1_categories <- list( + chm = "CHEMISTRY", + hem = "HEMATOLOGY" +) + +ad_domain <- "adlb" + +# MCRIT indices to use (e.g. c(1, 2) for CRIT1/CRIT2, c(2, 3) for CRIT2/CRIT3) +crit_indices <- c(1, 2) + +## if the option TRTEMFL needs to be added to the TLF -- ensure the same setting as in tsflab04 +trtemfl <- TRUE + + +################################################################################ +# Initial processing of data + check if table is valid for trial: +################################################################################ +adlb_complete <- adlb_jnj + +################################################################################ +# Process markedly abnormal values from spreadsheet: +################################################################################ + +### Markedly Abnormal spreadsheet +markedlyabnormal_file <- read_path(datapath, "markedlyabnormal.xlsx") + +markedlyabnormal_sheets <- readxl::excel_sheets(markedlyabnormal_file) + +lbmarkedlyabnormal_defs <- readxl::read_excel( + markedlyabnormal_file, + sheet = toupper(ad_domain) +) |> + filter(PARAMCD != "Parameter Code") + +# Data Fix needed on abnormal file: This section should be removed on actual study data +# No criteria available on markedlyabnormal file — using manual values +crit_defs_data <- tibble::tribble( + ~PARAMCD, ~VARNAME, ~CRIT, + "ALT", "CRIT2", ">3xULN", + "ALT", "CRIT1", ">2xULN", + "AST", "CRIT2", ">3xULN", + "AST", "CRIT1", ">2xULN", + "BILI", "CRIT1", ">2xULN", + "BILI", "CRIT2", ">3xULN", + "CK", "CRIT1", ">2xULN", + "CK", "CRIT2", ">3xULN", + "CREAT", "CRIT1", ">2xULN", + "GGT", "CRIT1", ">2xULN", + "GGT", "CRIT2", ">3xULN", + "HGB", "CRIT1", ">2xULN", + "HGB", "CRIT2", ">3xULN", + "PROT", "CRIT1", ">2xULN", + "PROT", "CRIT2", ">3xULN", + "SODIUM", "CRIT2", ">3xULN", + "SODIUM", "CRIT1", ">2xULN", + "WBC", "CRIT1", ">2xULN", + "WBC", "CRIT2", ">3xULN" +) |> + mutate(CRITN = as.character(as.numeric(factor(CRIT))), SEX = NA_character_) + +lbmarkedlyabnormal_defs <- bind_rows(lbmarkedlyabnormal_defs, crit_defs_data) +# End of data fix: code should be removed if abnormal file have data + +CRITs <- paste0("CRIT", crit_indices) +CRITsFLs <- paste0("CRIT", crit_indices, "FL") + +CRITs_def <- unique( + lbmarkedlyabnormal_defs |> + filter(VARNAME %in% CRITs) |> + select(PARAMCD, VARNAME, CRIT, SEX) +) + +### convert dataframe into label_map that can be used with the a_freq_j afun function +xlabel_map <- CRITs_def |> + rename(var = VARNAME, label = CRIT) |> + select(PARAMCD, var, label) + +################################################################################ +# Process Data: +################################################################################ +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> + select(USUBJID, all_of(c(popfl, trtvar))) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +adsl$rrisk_header <- "Risk Difference (%) (95% CI)" +adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +adlb00 <- adlb_complete |> + filter(ONTRTFL == "Y") |> + # Filter to keep records where at least one of the specified CRIT flags is "Y" + filter(if_any(all_of(paste0("CRIT", crit_indices, "FL")), ~ . == "Y")) |> + select( + USUBJID, + PARCAT1, + PARCAT2, + PARCAT3, + PARCAT3N, + ONTRTFL, + TRTEMFL, + PARAM, + PARAMCD, + AVISITN, + AVISIT, + AVAL, + all_of(paste0("CRIT", crit_indices)), + all_of(paste0("CRIT", crit_indices, "FL")) + ) |> + inner_join(adsl) + +#### DO NOT filter by TRTEMFL == "Y" — that removes subjects from denominator +#### Instead: set CRIT_LABEL to NA when TRTEMFL != "Y", row stays for N count +if (trtemfl) { + adlb00 <- adlb00 |> + mutate( + across( + all_of(CRITsFLs), + ~ case_when( + . == "Y" & !is.na(TRTEMFL) & TRTEMFL == "Y" ~ "Y", + TRUE ~ "N" + ) + ) + ) +} + +# Filter to keep records where at least one of the specified CRIT flags is "Y" +adlb00 <- adlb00 |> + filter(if_any(all_of(paste0("CRIT", crit_indices, "FL")), ~ . == "Y")) + +adlb_crit_list <- lapply(crit_indices, function(idx) { + fl_var <- paste0("CRIT", idx, "FL") + crit_var <- paste0("CRIT", idx) + adlb00 |> + filter(.data[[fl_var]] == "Y") |> + mutate( + CRIT_IDX = idx, + CRIT_FL = fl_var, + CRIT_LABEL = .data[[crit_var]] + ) +}) + +# Derive PARAMCD sort order: PARCAT3N -> PARAM, from deduplicated reference +paramcd_order <- adlb00 |> + distinct(PARCAT1, PARCAT3N, PARCAT3, PARAM, PARAMCD) |> + arrange(PARCAT1, PARCAT3N, PARCAT3, PARAM) |> + pull(PARAMCD) + +adlb_crit <- bind_rows(adlb_crit_list) |> + mutate(PARAMCD = ordered(PARAMCD, levels = paramcd_order)) +################################################################################ +##### Build xlabel_map (CRIT_LABEL levels) from spreadsheet +################################################################################ + +xlabel_map_final <- xlabel_map |> + filter(var %in% CRITs) |> + inner_join( + unique(adlb00 |> select(PARAMCD, PARAM, PARCAT1, PARCAT3N, PARCAT3)), + by = "PARAMCD" + ) |> + arrange(PARCAT1, PARCAT3N, PARCAT3, PARAM, PARAMCD, var) + +# Set CRIT_LABEL factor levels from spreadsheet order (scoped per PARAMCD via label_map) +crit_label_levels <- unique(xlabel_map_final$label) +adlb_crit <- adlb_crit |> + mutate(CRIT_LABEL = factor(CRIT_LABEL, levels = crit_label_levels)) + +# Build label_map for a_freq_j: PARAMCD-conditional mapping of CRIT_LABEL levels +crit_label_map <- xlabel_map_final |> + rename(value = label) |> + select(PARAMCD, value) |> + mutate(label = value) + +################################################################################ +# Define layout and build table: +################################################################################ + +.extra_args_rr <- list( + method = "wald", + denom = "n_df", + ref_path = ref_path, + riskdiff = TRUE, + .stats = c("count_unique_fraction"), + label_map = crit_label_map +) + +################################################################################ +# Core function to produce shell for specific parcat3 selection +################################################################################ + +build_result_parcat1 <- function( + df = adlb_crit, + PARCAT1sel = NULL, + tblid, + .adsl = adsl, + map = xlabel_map_final, + extra_args_rr = .extra_args_rr, + .trtvar = trtvar, + .ref_path = ref_path, + .ctrl_grp = ctrl_grp, + .combined_colspan_trt = combined_colspan_trt, + .crit_indices = crit_indices +) { + lyt_filter <- function(PARCAT1sel = NULL, map, df) { + if (!is.null(PARCAT1sel)) { + map <- map |> + filter(toupper(PARCAT1) %in% toupper(PARCAT1sel)) + } + + lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + + if (.combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(.trtvar, split_fun = mysplit) + } else { + lyt <- lyt |> split_cols_by(.trtvar) + } + + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + .trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels(.ctrl_grp) + ) + + lyt <- lyt |> + split_rows_by( + "PARAMCD", + labels_var = "PARAM", + split_label = "Laboratory Test", + child_labels = "visible", + section_div = " ", + label_pos = "topleft", + split_fun = drop_split_levels + ) |> + append_topleft(" Criteria") |> + summarize_row_groups( + var = "PARAMCD", + cfun = a_freq_j, + extra_args = list( + .stats = "n_df", + label = "N", + riskdiff = FALSE + ) + ) |> + analyze( + "CRIT_LABEL", + a_freq_j, + extra_args = extra_args_rr, + show_labels = "hidden" + ) + + return(lyt) + } + + if (!is.null(PARCAT1sel)) { + df <- df |> + filter(toupper(PARCAT1) %in% toupper(PARCAT1sel)) + } + + lyt <- lyt_filter(PARCAT1sel = PARCAT1sel, map = map, df = df) + + result <- build_table(lyt, df, alt_counts_df = .adsl, round_type = "sas") + + ################################################################################ + # Post Processing + ################################################################################ + + # Remove unwanted column counts + result <- remove_col_count(result) + + ################################################################################ + # Set title + ################################################################################ + + result <- set_titles(result, tab_titles) + + fileid <<- write_path(opath, tblid) + + return(result) +} + +################################################################################ +# Define layout and build table: +################################################################################ + +result <- build_result_parcat1( + PARCAT1sel = parcat1_categories[["hem"]], + tblid = tblid +) + +colwidth <- c(34, 23, 23, 23, 23, 30, 33) + +fileid <- write_path(opath, tblid) + +tt_to_tlgrtf( + # colwidths = colwidth, + result, + file = fileid, + orientation = "landscape" +) diff --git a/tests/testthat/source_code/tsflab03.R b/tests/testthat/source_code/tsflab03.R index 3dc482ee..84f55f83 100644 --- a/tests/testthat/source_code/tsflab03.R +++ b/tests/testthat/source_code/tsflab03.R @@ -1,24 +1,4 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab03 -## R version: 4.2.1 -## Short Description: Program to create tsflab03: Subjects With -## ≥1 Laboratory Values With Elevated or Low Values -## Based on Worst On-treatment Value Using NCI-CTCAE Criteria -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab03.rtf -## Remarks: Should only be used when abnormalities are based upon lab toxicity grading -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - +#### BEFORE YOU START USING THIS PROGRAM ENSURE THE FOLLOWING: For your trial you should EITHER use lab toxicity grading (lbtoxgrade file) or Abnormality criteria (markedly abnormal file) ################################################################################ # Prep Environment ################################################################################ @@ -35,19 +15,46 @@ library(junco) tblid <- "TSFLAB03" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) popfl <- "SAFFL" + trtvar <- "TRT01A" + ctrl_grp <- "Placebo" +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + ## if the option TRTEMFL needs to be added to the TLF trtemfl <- TRUE +## ANL flag variable for worst on-treatment low grade +anl_low_fl <- "ANL04FL" + +## ANL flag variable for worst on-treatment high grade +anl_high_fl <- "ANL05FL" + ## For analysis on SI units: use adlb dataset ## For analysis on Conventional units: use adlbc dataset -- shell is in conventional units @@ -58,47 +65,35 @@ ad_domain <- "ADLB" ################################################################################ adlb_complete <- adlb_jnj - -## parcat5 and 6 options : - -availparcat56 <- c( - "Investigations", - "Metabolism and nutritional disorders", - "Renal and urinary disorders", - "Blood and lymphatic system disorders" -) - -## resrict to some -selparcat56 <- availparcat56[c(1, 2, 4)] - -## get all -selparcat56 <- availparcat56 - -lbtoxgrade_file <- file.path(datapath, "lbtoxgrade.xlsx") -lbtoxgrade_sheets <- readxl::excel_sheets(path = lbtoxgrade_file) +lbtoxgrade_file <- read_path(datapath, "lbtoxgrade.xlsx") ### CTC5 or DAIDS21c : default CTC5 lbtoxgrade_defs <- readxl::read_excel(lbtoxgrade_file, sheet = "CTC5") lbtoxgrade_defs <- unique( - lbtoxgrade_defs %>% + lbtoxgrade_defs |> select(TOXTERM, TOXGRD, INDICATR) -) %>% +) |> mutate( ATOXDSCLH = TOXTERM, ATOXGRLH = paste("Grade", TOXGRD) - ) %>% - rename(ATOXDIR = INDICATR) %>% + ) |> + rename(ATOXDIR = INDICATR) |> select(ATOXDSCLH, ATOXGRLH, ATOXDIR) - ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> select(USUBJID, all_of(c(popfl, trtvar))) adsl$colspan_trt <- factor( @@ -118,7 +113,7 @@ colspan_trt_map <- create_colspan_map( trt_var = trtvar ) -adlb00 <- adlb_complete %>% +adlb00 <- adlb_complete |> select( USUBJID, AVISITN, @@ -132,17 +127,16 @@ adlb00 <- adlb_complete %>% APOBLFL, ABLFL, LVOTFL - ) %>% - inner_join(adsl) %>% + ) |> + inner_join(adsl) |> mutate( ATOXGRL = as.character(ATOXGRL), ATOXGRH = as.character(ATOXGRH) - ) %>% + ) |> relocate( - ., USUBJID, - ANL04FL, - ANL05FL, + all_of(anl_low_fl), + all_of(anl_high_fl), ONTRTFL, TRTEMFL, AVISIT, @@ -157,38 +151,9 @@ adlb00 <- adlb_complete %>% ABLFL ) - -# adlb00 <- adlb00 #%>% -## APT comment on PARCAT6 : -## HGB and WBC : Set to "Blood and lymphatic system disorders". -## HGB and WBC parameter are in 2 categories, one for the high and another one for the low direction grading. -## Anemia (HGB low) and Leukocytosis (WBC high) are in the category "Blood and lymphatic system disorders". -## The grading in the opposite directions are categorized under "Investigations". -## Therefor, both PARCAT5 and PARCAT6 are populated for HGB abd WBC. -## Deal with what is needed at later level, when we have splitted low and high -# mutate(PARCAT56 = coalesce(PARCAT6,PARCAT5)) %>% -# mutate(PARCAT56 = factor(PARCAT56,levels=unique(c(levels(adlb_complete$PARCAT6),levels(adlb_complete$PARCAT5))))) - -# obj_label(adlb00$PARCAT56) <- "Combined PARCAT56" - -### important: previous actions lost the label of variables - -adlb00 <- var_relabel_list(adlb00, var_labels(adlb_complete, fill = T)) - -parcat <- unique( - adlb00 %>% - select(starts_with("PARCAT"), PARAMCD, PARAM, ATOXDSCL, ATOXDSCH) %>% - filter(!(is.na(PARCAT5) & is.na(PARCAT6))) -) - - -### data preparation - -if (all(selparcat56 != "")) { - filtered_adlb <- adlb00 %>% - filter((PARCAT5 %in% selparcat56) | (PARCAT6 %in% selparcat56)) -} - +# Filtered ADLB +filtered_adlb <- adlb00 |> + filter(PARCAT4 == "Graded tests" & ONTRTFL == "Y") ### low grades : ATOXDSCL ATOXGRL ANL04FL ### Note on Worst On-treatment @@ -197,25 +162,25 @@ if (all(selparcat56 != "")) { ### if derivation of ANL04FL/ANL05FL is not restricted to ONTRTFL records, adding ONTRTFL here will not give the correct answer either ### as mixing worst with other period is not giving the proper selection !!! -filtered_adlb_low <- filtered_adlb %>% - filter(ANL04FL == "Y" & !is.na(ATOXDSCL) & !is.na(ATOXGRL)) %>% +filtered_adlb_low <- filtered_adlb |> + filter(.data[[anl_low_fl]] == "Y" & !is.na(ATOXDSCL) & !is.na(ATOXGRL)) |> mutate( ATOXDSCLH = ATOXDSCL, ATOXGRLH = ATOXGRL, ATOXDIR = "LOW" - ) %>% - select(USUBJID, starts_with("PAR"), starts_with("ATOX"), TRTEMFL) %>% + ) |> + select(USUBJID, starts_with("PAR"), starts_with("ATOX"), TRTEMFL) |> select(-c(ATOXGRL, ATOXGRH, ATOXDSCL, ATOXDSCH)) ### high grades: ATOXDSCH ATOXGRH ANL05FL -filtered_adlb_high <- filtered_adlb %>% - filter(ANL05FL == "Y" & !is.na(ATOXDSCH) & !is.na(ATOXGRH)) %>% +filtered_adlb_high <- filtered_adlb |> + filter(.data[[anl_high_fl]] == "Y" & !is.na(ATOXDSCH) & !is.na(ATOXGRH)) |> mutate( ATOXDSCLH = ATOXDSCH, ATOXGRLH = ATOXGRH, ATOXDIR = "HIGH" - ) %>% - select(USUBJID, starts_with("PAR"), starts_with("ATOX"), TRTEMFL) %>% + ) |> + select(USUBJID, starts_with("PAR"), starts_with("ATOX"), TRTEMFL) |> select(-c(ATOXGRL, ATOXGRH, ATOXDSCL, ATOXDSCH)) ## combine Low and high into adlb_tox @@ -223,38 +188,14 @@ filtered_adlb_tox <- bind_rows( filtered_adlb_low, filtered_adlb_high - ) %>% - select(-c(ATOXGR, ATOXGRN)) %>% + ) |> + select(-c(ATOXGR, ATOXGRN)) |> inner_join(adsl) -### correction of proper category (PARCAT56) for HGB (LOW) and WBC (HIGH) -filtered_adlb_tox <- - filtered_adlb_tox %>% - mutate( - PARCAT56 = case_when( - PARAMCD == "HGB" & ATOXDIR == "LOW" ~ PARCAT6, - PARAMCD == "WBC" & ATOXDIR == "HIGH" ~ PARCAT6, - - ### fix on synthetic data !!!! - PARAMCD == "WBC" & ATOXDIR == "LOW" ~ "Investigations", - TRUE ~ PARCAT5 - ) - ) %>% - mutate( - PARCAT56 = factor( - PARCAT56, - levels = unique(c( - "Blood and lymphatic system disorders", - levels(adlb_complete$PARCAT5) - )) - ) - ) - - #### DO NOT USE TRTEMFL = Y in filter, as this will remove subjects from both numerator and denominator #### instead : set ATOXGRLH to a non-reportable value (ie Grade 0) and keep in dataset if (trtemfl) { - filtered_adlb_tox <- filtered_adlb_tox %>% + filtered_adlb_tox <- filtered_adlb_tox |> mutate( ATOXGRLH = case_when( is.na(TRTEMFL) | TRTEMFL != "Y" ~ "0", @@ -263,23 +204,21 @@ if (trtemfl) { ) } - ## convert some to factors -- lty will fail if these are not factors filtered_adlb_tox <- - filtered_adlb_tox %>% + filtered_adlb_tox |> mutate( ATOXGRLH = factor(paste("Grade", ATOXGRLH), levels = paste("Grade", 0:5)), ATOXDIR = factor(ATOXDIR, levels = c("LOW", "HIGH")) ) - filtered_adlb_tox <- unique( filtered_adlb_tox ) -check_non_unique_subject <- filtered_adlb_tox %>% - group_by(USUBJID, PARAMCD, ATOXDSCLH) %>% - summarize(n_subject = n()) %>% +check_non_unique_subject <- filtered_adlb_tox |> + group_by(USUBJID, PARAMCD, ATOXDSCLH) |> + summarize(n_subject = n()) |> filter(n_subject > 1) if (nrow(check_non_unique_subject)) { @@ -288,52 +227,33 @@ if (nrow(check_non_unique_subject)) { ) } - -params <- unique( - filtered_adlb_tox %>% select(PARCAT56, PARAMCD, PARAM, ATOXDSCLH, ATOXDIR) -) - -all_params <- unique( - adlb_complete %>% - filter(!(is.na(PARCAT5) & is.na(PARCAT6))) %>% - select(PARCAT5, PARCAT6, PARAMCD, PARAM, ATOXDSCL, ATOXDSCH) -) - - ### add relevant extra vars to lbtoxgrade_defs, only restrict to those actually in trial -lbtoxgrade_defs <- lbtoxgrade_defs %>% +lbtoxgrade_defs <- lbtoxgrade_defs |> inner_join( - ., unique( - filtered_adlb_tox %>% - select(PARAMCD, PARAM, ATOXDIR, ATOXDSCLH, PARCAT5, PARCAT6, PARCAT56) + filtered_adlb_tox |> + select(PARAMCD, PARAM, ATOXDIR, ATOXDSCLH) ), relationship = "many-to-many" ) ### Define param_map to be used in layout -param_map <- lbtoxgrade_defs %>% - select(PARCAT56, PARAM, PARAMCD, ATOXDIR, ATOXDSCLH, ATOXGRLH) %>% +param_map <- lbtoxgrade_defs |> + select(PARAM, PARAMCD, ATOXDIR, ATOXDSCLH, ATOXGRLH) |> ### for proper sorting: add factor levels to PARAMCD, ATOXDIR - mutate( - PARAMCD = factor(PARAMCD, levels = levels(adlb00$PARAMCD)), - ATOXDIR = factor(ATOXDIR, levels = c("LOW", "HIGH")) - ) %>% - # ### actual sorting - # arrange(PARCAT56,PARAMCD,ATOXDIR,ATOXGRLH) %>% - ### actual sorting -- all alphabetic on output - arrange(PARCAT56, ATOXDSCLH) %>% + mutate(ATOXDIR = factor(ATOXDIR, levels = c("LOW", "HIGH"))) |> + ### actual sorting -- alphabetic by base term, LOW before HIGH within same term + mutate(base_term = sub(", (low|high)$", "", as.character(ATOXDSCLH), ignore.case = TRUE)) |> + arrange(base_term, ATOXDIR) |> + select(-base_term) |> ### !!!! no factors are allowed in this split_fun map definition mutate( - PARCAT56 = as.character(PARCAT56), PARAMCD = as.character(PARAMCD), PARAM = as.character(PARAM), ATOXDIR = as.character(ATOXDIR), - ATOXDSCLH = as.character(ATOXDSCLH) - ) # %>% -### !!!! do not remove Grade 0 here, as this would lead to incorrect N and % derivation -### filter(ATOXGRLH != "Grade 0") -### Grade 0 will be removed as a post-processing step + ATOXDSCLH = as.character(ATOXDSCLH), + ATOXGRLH = as.character(ATOXGRLH) + ) ################################################################################ # Define layout and build table: @@ -346,35 +266,27 @@ extra_args_rr <- list( ref_path = ref_path, .stats = c("denom", "count_unique_fraction") ) -extra_args_rr2 <- list( - method = "wald", - denom = "n_df", - ref_path = ref_path, - .stats = c("denom", "count_unique_denom_fraction") -) -lyt0 <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% +lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> ### first columns split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> split_cols_by(trtvar) +} + +lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", split_fun = remove_split_levels(ctrl_grp) - ) %>% - split_rows_by( - "PARCAT56", - label_pos = "topleft", - child_labels = "visible", - split_label = "NCI-CTCAE Category", - ### trim_levels_to_map needs to be applied at ALL split_rows_by levels - split_fun = trim_levels_to_map(param_map), - section_div = " " - ) %>% + ) |> split_rows_by( "ATOXDSCLH", label_pos = "topleft", @@ -383,12 +295,8 @@ lyt0 <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% ### trim_levels_to_map needs to be applied at ALL split_rows_by levels split_fun = trim_levels_to_map(param_map), section_div = " " - ) %>% - append_topleft(" Grade, n (%)") - -# version without explicit denominator (as in shell) -lyt <- lyt0 %>% - # for testing, it is sometimes convenient to explicitely show the used denominator + ) |> + append_topleft(" Grade, n (%)") |> analyze( "ATOXGRLH", a_freq_j, @@ -397,22 +305,7 @@ lyt <- lyt0 %>% indent_mod = 0L ) -result <- build_table(lyt, filtered_adlb_tox, alt_counts_df = adsl) - - -# version with explicit denominator (for verification) -lyt2 <- lyt0 %>% - # for testing, it is sometimes convenient to explicitely show the used denominator - analyze( - "ATOXGRLH", - a_freq_j, - extra_args = extra_args_rr2, - show_labels = "visible", - indent_mod = 0L - ) - -### apply layout -result2 <- build_table(lyt2, filtered_adlb_tox, alt_counts_df = adsl) +result <- build_table(lyt, filtered_adlb_tox, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: @@ -428,26 +321,25 @@ remove_grade0 <- function(tr) { } } -result <- result %>% prune_table(prune_func = keep_rows(remove_grade0)) -result2 <- result2 %>% prune_table(prune_func = keep_rows(remove_grade0)) +result <- result |> prune_table(prune_func = keep_rows(remove_grade0)) ################################################################################ # Remove colcount from rrisk_header: ################################################################################ result <- remove_col_count(result) -result2 <- remove_col_count(result2) ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(62, 21, 21, 21, 33, 35) + +colwidth <- c(54, 19, 21, 21, 21, 35, 33) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab03a.R b/tests/testthat/source_code/tsflab03a.R deleted file mode 100644 index 523121d8..00000000 --- a/tests/testthat/source_code/tsflab03a.R +++ /dev/null @@ -1,493 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab03a -## R version: 4.2.1 -## Short Description: Program to create tsflab03a: Subjects With -## ≥1 Laboratory Values With Elevated or Low Values -## Based on Worst On-treatment Value Using NCI-CTCAE Criteria -## by [Subgroup] -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab03a.rtf -## Remarks: Should only be used when abnormalities are based upon lab toxicity grading -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFLAB03a" -fileid <- write_path(opath, tblid) -titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -popfl <- "SAFFL" -trtvar <- "TRT01A" -ctrl_grp <- "Placebo" - -subgrpvar <- "AGEGR1" -subgrplbl <- "Age: %s years" - -page_by <- TRUE # Set page_by TRUE/FALSE if you (do not) wish to start a new page after a new subgroup -indent_adj <- -1L -if (page_by) { - indent_adj <- 0L -} - -## if the option TRTEMFL needs to be added to the TLF -trtemfl <- FALSE - -## For analysis on SI units: use adlb dataset -## For analysis on Conventional units: use adlbc dataset -- shell is in conventional units - -ad_domain <- "ADLB" - -################################################################################ -# Initial processing of data + check if table is valid for trial: -################################################################################ -adlb_complete <- adlb_jnj - - -## parcat5 and 6 options : - -availparcat56 <- c( - "Investigations", - "Metabolism and nutritional disorders", - "Renal and urinary disorders", - "Blood and lymphatic system disorders" -) - -## resrict to some -selparcat56 <- availparcat56[c(1, 2, 4)] - -## get all -selparcat56 <- availparcat56 - -lbtoxgrade_file <- read_path(datapath, "lbtoxgrade.xlsx") -lbtoxgrade_sheets <- readxl::excel_sheets(path = lbtoxgrade_file) - -### CTC5 or DAIDS21c : default CTC5 - -lbtoxgrade_defs <- readxl::read_excel(lbtoxgrade_file, sheet = "CTC5") - -lbtoxgrade_defs <- unique( - lbtoxgrade_defs %>% - select(TOXTERM, TOXGRD, INDICATR) -) %>% - mutate( - ATOXDSCLH = TOXTERM, - ATOXGRLH = paste("Grade", TOXGRD) - ) %>% - rename(ATOXDIR = INDICATR) %>% - select(ATOXDSCLH, ATOXGRLH, ATOXDIR) - - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select(USUBJID, all_of(c(popfl, trtvar, subgrpvar))) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -adsl$rrisk_header <- "Risk Difference (%) (95% CI)" -adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - - -## for checking row_counts on AGEGR1 : should consist with counts from ADSL -adsl_agegr1 <- adsl %>% - select(all_of(c(trtvar, subgrpvar))) %>% - group_by(across(all_of(c(trtvar, subgrpvar)))) %>% - summarise(n = n()) - -adlb00 <- adlb_complete %>% - select( - USUBJID, - AVISITN, - AVISIT, - starts_with("PAR"), - starts_with("ATOX"), - starts_with("ANL"), - ONTRTFL, - TRTEMFL, - AVAL, - APOBLFL, - ABLFL, - LVOTFL - ) %>% - inner_join(adsl) %>% - mutate( - ATOXGRL = as.character(ATOXGRL), - ATOXGRH = as.character(ATOXGRH) - ) %>% - relocate( - ., - USUBJID, - all_of(subgrpvar), - ANL04FL, - ANL05FL, - ONTRTFL, - TRTEMFL, - AVISIT, - ATOXGRL, - ATOXGRH, - ATOXDSCL, - ATOXDSCH, - PARAMCD, - AVISIT, - AVAL, - APOBLFL, - ABLFL - ) - - -adlb00 <- adlb00 # %>% -## APT comment on PARCAT6 : -## HGB and WBC : Set to "Blood and lymphatic system disorders". -## HGB and WBC parameter are in 2 categories, one for the high and another one for the low direction grading. -## Anemia (HGB low) and Leukocytosis (WBC high) are in the category "Blood and lymphatic system disorders". -## The grading in the opposite directions are categorized under "Investigations". -## Therefor, both PARCAT5 and PARCAT6 are populated for HGB abd WBC. -## Deal with what is needed at later level, when we have splitted low and high -# mutate(PARCAT56 = coalesce(PARCAT6,PARCAT5)) %>% -# mutate(PARCAT56 = factor(PARCAT56,levels=unique(c(levels(adlb_complete$PARCAT6),levels(adlb_complete$PARCAT5))))) - -# obj_label(adlb00$PARCAT56) <- "Combined PARCAT56" - -### important: previous actions lost the label of variables - -adlb00 <- var_relabel_list(adlb00, var_labels(adlb_complete, fill = T)) - -parcat <- unique( - adlb00 %>% - select(starts_with("PARCAT"), PARAMCD, PARAM, ATOXDSCL, ATOXDSCH) %>% - filter(!(is.na(PARCAT5) & is.na(PARCAT6))) -) - - -### data preparation - -if (all(selparcat56 != "")) { - filtered_adlb <- adlb00 %>% - filter((PARCAT5 %in% selparcat56) | (PARCAT6 %in% selparcat56)) -} - - -### low grades : ATOXDSCL ATOXGRL ANL04FL -### Note on Worst On-treatment -### note: by filter ANL04FL/ANL05FL, this table is restricted to On-treatment values, per definition of ANL04FL/ANL05FL -### therefor, no need to add ONTRTFL in filter -### if derivation of ANL04FL/ANL05FL is not restricted to ONTRTFL records, adding ONTRTFL here will not give the correct answer either -### as mixing worst with other period is not giving the proper selection !!! - -filtered_adlb_low <- filtered_adlb %>% - filter(ANL04FL == "Y" & !is.na(ATOXDSCL) & !is.na(ATOXGRL)) %>% - mutate( - ATOXDSCLH = ATOXDSCL, - ATOXGRLH = ATOXGRL, - ATOXDIR = "LOW" - ) %>% - select(USUBJID, starts_with("PAR"), starts_with("ATOX"), TRTEMFL) %>% - select(-c(ATOXGRL, ATOXGRH, ATOXDSCL, ATOXDSCH)) - -### high grades: ATOXDSCH ATOXGRH ANL05FL -filtered_adlb_high <- filtered_adlb %>% - filter(ANL05FL == "Y" & !is.na(ATOXDSCH) & !is.na(ATOXGRH)) %>% - mutate( - ATOXDSCLH = ATOXDSCH, - ATOXGRLH = ATOXGRH, - ATOXDIR = "HIGH" - ) %>% - select(USUBJID, starts_with("PAR"), starts_with("ATOX"), TRTEMFL) %>% - select(-c(ATOXGRL, ATOXGRH, ATOXDSCL, ATOXDSCH)) - -## combine Low and high into adlb_tox -filtered_adlb_tox <- - bind_rows( - filtered_adlb_low, - filtered_adlb_high - ) %>% - select(-c(ATOXGR, ATOXGRN)) %>% - inner_join(adsl) - -### correction of proper category (PARCAT56) for HGB (LOW) and WBC (HIGH) -filtered_adlb_tox <- - filtered_adlb_tox %>% - mutate( - PARCAT56 = case_when( - PARAMCD == "HGB" & ATOXDIR == "LOW" ~ PARCAT6, - PARAMCD == "WBC" & ATOXDIR == "HIGH" ~ PARCAT6, - - ### fix on synthetic data !!!! - PARAMCD == "WBC" & ATOXDIR == "LOW" ~ "Investigations", - TRUE ~ PARCAT5 - ) - ) %>% - mutate( - PARCAT56 = factor( - PARCAT56, - levels = unique(c( - "Blood and lymphatic system disorders", - levels(adlb_complete$PARCAT5) - )) - ) - ) - - -#### DO NOT USE TRTEMFL = Y in filter, as this will remove subjects from both numerator and denominator -#### instead : set ATOXGRLH to a non-reportable value (ie Grade 0) and keep in dataset -if (trtemfl) { - filtered_adlb_tox <- filtered_adlb_tox %>% - mutate( - ATOXGRLH = case_when( - is.na(TRTEMFL) | TRTEMFL != "Y" ~ "0", - TRUE ~ ATOXGRLH - ) - ) -} - - -## convert some to factors -- lty will fail if these are not factors -filtered_adlb_tox <- - filtered_adlb_tox %>% - mutate( - ATOXGRLH = factor(paste("Grade", ATOXGRLH), levels = paste("Grade", 0:5)), - ATOXDIR = factor(ATOXDIR, levels = c("LOW", "HIGH")) - ) - - -filtered_adlb_tox <- unique( - filtered_adlb_tox -) - -check_non_unique_subject <- filtered_adlb_tox %>% - group_by(USUBJID, PARAMCD, ATOXDSCLH) %>% - summarize(n_subject = n()) %>% - filter(n_subject > 1) - -if (nrow(check_non_unique_subject)) { - message( - "Please review your data selection process, subject has multiple records" - ) -} - - -params <- unique( - filtered_adlb_tox %>% select(PARCAT56, PARAMCD, PARAM, ATOXDSCLH, ATOXDIR) -) - -all_params <- unique( - adlb_complete %>% - filter(!(is.na(PARCAT5) & is.na(PARCAT6))) %>% - select(PARCAT5, PARCAT6, PARAMCD, PARAM, ATOXDSCL, ATOXDSCH) -) - -### add relevant extra vars to lbtoxgrade_defs, only restrict to those actually in trial -### Neutrophil Count Decreased (NEUTSG NEUT) is causing for the many-to-many warning -lbtoxgrade_defs <- lbtoxgrade_defs %>% - inner_join( - ., - unique( - filtered_adlb_tox %>% - select(PARAMCD, PARAM, ATOXDIR, ATOXDSCLH, PARCAT5, PARCAT6, PARCAT56) - ) - ) - - -### Define param_map to be used in layout -param_map <- lbtoxgrade_defs %>% - select(PARCAT56, PARAM, PARAMCD, ATOXDIR, ATOXDSCLH, ATOXGRLH) %>% - ### for proper sorting: add factor levels to PARAMCD, ATOXDIR - mutate( - PARAMCD = factor(PARAMCD, levels = levels(adlb00$PARAMCD)), - ATOXDIR = factor(ATOXDIR, levels = c("LOW", "HIGH")) - ) %>% - # ### actual sorting - # arrange(PARCAT56,PARAMCD,ATOXDIR,ATOXGRLH) %>% - ### actual sorting -- all alphabetic on output - arrange(PARCAT56, ATOXDSCLH) %>% - ### !!!! no factors are allowed in this split_fun map definition - mutate( - PARCAT56 = as.character(PARCAT56), - PARAMCD = as.character(PARAMCD), - PARAM = as.character(PARAM), - ATOXDIR = as.character(ATOXDIR), - ATOXDSCLH = as.character(ATOXDSCLH) - ) # %>% -### !!!! do not remove Grade 0 here, as this would lead to incorrect N and % derivation -### filter(ATOXGRLH != "Grade 0") -### Grade 0 will be removed as a post-processing step - -################################################################################ -# Define layout and build table: -################################################################################ - -extra_args_rr <- list( - method = "wald", - denom = "n_df", - ref_path = ref_path, - .stats = c("denom", "count_unique_fraction"), - denom_by = subgrpvar -) -extra_args_rr2 <- list( - method = "wald", - denom = "n_df", - ref_path = ref_path, - .stats = c("denom", "count_unique_denom_fraction"), - denom_by = subgrpvar -) - - -lyt0 <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% - ### first columns - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels(ctrl_grp) - ) %>% - split_rows_by( - subgrpvar, - label_pos = "hidden", - section_div = " ", - split_fun = drop_split_levels, - page_by = page_by - ) %>% - ### - summarize_row_groups( - var = subgrpvar, - cfun = a_freq_j, - extra_args = list( - label_fstr = subgrplbl, - denom = "n_altdf", - denom_by = subgrpvar, - riskdiff = FALSE, - extrablankline = TRUE, - .stats = c("n_altdf") - ) - ) %>% - split_rows_by( - "PARCAT56", - label_pos = "topleft", - child_labels = "visible", - split_label = "NCI-CTCAE Category", - ### trim_levels_to_map needs to be applied at ALL split_rows_by levels - split_fun = trim_levels_to_map(param_map), - section_div = " ", - indent_mod = indent_adj, - ) %>% - split_rows_by( - "ATOXDSCLH", - label_pos = "topleft", - child_labels = "visible", - split_label = "Laboratory Test", - ### trim_levels_to_map needs to be applied at ALL split_rows_by levels - split_fun = trim_levels_to_map(param_map), - section_div = " " - ) %>% - append_topleft(" Grade, n (%)") - -# version without explicit denominator (as in shell) -lyt <- lyt0 %>% - # for testing, it is sometimes convenient to explicitely show the used denominator - analyze( - "ATOXGRLH", - a_freq_j, - extra_args = extra_args_rr, - show_labels = "hidden", - indent_mod = 0L - ) - -result <- build_table(lyt, filtered_adlb_tox, alt_counts_df = adsl) - -# version with explicit denominator (for verification) -lyt2 <- lyt0 %>% - # for testing, it is sometimes convenient to explicitely show the used denominator - analyze( - "ATOXGRLH", - a_freq_j, - extra_args = extra_args_rr2, - show_labels = "visible", - indent_mod = 0L - ) - -### apply layout -result2 <- build_table(lyt2, filtered_adlb_tox, alt_counts_df = adsl) - -################################################################################ -# Post-Processing: -# - Remove Grade 0 line -# - Remove colcount from rrisk_header -################################################################################ - -remove_grade0 <- function(tr) { - if (is(tr, "DataRow") & (tr@label == "Grade 0")) { - return(FALSE) - } else { - return(TRUE) - } -} - -result <- result %>% prune_table(prune_func = keep_rows(remove_grade0)) - -################################################################################ -# Remove colcount from rrisk_header: -################################################################################ - -result <- remove_col_count(result) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 21, 21, 21, 37, 37) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab04a.R b/tests/testthat/source_code/tsflab04a.R index 3496553e..084a4aaa 100644 --- a/tests/testthat/source_code/tsflab04a.R +++ b/tests/testthat/source_code/tsflab04a.R @@ -1,24 +1,4 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab04a -## R version: 4.2.1 -## Short Description: Program to create tsflab04a: -## Subjects With [Last/Any] On-treatment -## Chemistry Values [≥ Level 2] Criteria -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab04a.rtf -## Remarks: Should only be used when abnormalities are based upon markedly abnormal file -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - +#### BEFORE YOU START USING THIS PROGRAM ENSURE THE FOLLOWING: For your trial you should EITHER use lab toxicity grading (lbtoxgrade file) or Abnormality criteria (markedly abnormal file) ################################################################################ # Prep Environment ################################################################################ @@ -37,16 +17,38 @@ test_stop <- FALSE #### !!!! set to FALSE for actual study!! tblid <- "TSFLAB04a" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) popfl <- "SAFFL" + trtvar <- "TRT01A" + ctrl_grp <- "Placebo" +# Add Active Study Agent Combined column +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + level_threshold <- "2" ## For analysis on SI units: use adlb dataset @@ -69,73 +71,75 @@ trtemfl <- TRUE ################################################################################ adlb_complete <- adlb_jnj - ################################################################################ # Retrieve markedly abnormal values from spreadsheet: ################################################################################ ### Markedly Abnormal spreadsheet -markedlyabnormal_file <- file.path(datapath, "markedlyabnormal.xlsx") +markedlyabnormal_file <- read_path(datapath, "markedlyabnormal.xlsx") + + +markedlyabnormal_sheets <- readxl::excel_sheets(markedlyabnormal_file) lbmarkedlyabnormal_defs <- readxl::read_excel( markedlyabnormal_file, sheet = toupper(ad_domain) -) %>% +) |> filter(PARAMCD != "Parameter Code") MCRITs <- unique( - lbmarkedlyabnormal_defs %>% - filter(!stringr::str_ends(VARNAME, "ML")) %>% + lbmarkedlyabnormal_defs |> + filter(!stringr::str_ends(VARNAME, "ML")) |> pull(VARNAME) ) MCRITs_def <- unique( - lbmarkedlyabnormal_defs %>% - filter(VARNAME %in% MCRITs) %>% + lbmarkedlyabnormal_defs |> + filter(VARNAME %in% MCRITs) |> select(PARAMCD, VARNAME, CRIT, SEX) -) %>% - mutate(VARNAME = paste0(VARNAME, "ML")) %>% +) |> + mutate(VARNAME = paste0(VARNAME, "ML")) |> rename(CRITNAME = CRIT) -MCRITs_def2 <- lbmarkedlyabnormal_defs %>% +MCRITs_def2 <- lbmarkedlyabnormal_defs |> filter(VARNAME %in% paste0(MCRITs, "ML")) -MCRITs_def3 <- MCRITs_def2 %>% - left_join(., MCRITs_def, relationship = "many-to-one") %>% +MCRITs_def3 <- MCRITs_def2 |> + left_join(MCRITs_def, relationship = "many-to-one") |> mutate( CRITx = paste0("(", stringr::str_split_i(CRIT, stringr::fixed("("), 2)) - ) %>% - mutate(CRITx = paste(CRITNAME, CRITx)) %>% - select(PARAMCD, SEX, VARNAME, CRITx, ORDER) %>% - mutate(VARNAME = paste0(VARNAME, "x")) %>% + ) |> + mutate(CRITx = paste(CRITNAME, CRITx)) |> + select(PARAMCD, SEX, VARNAME, CRITx, ORDER) |> + mutate(VARNAME = paste0(VARNAME, "x")) |> mutate(CRITn = as.character(4 - as.numeric(ORDER))) ### the threshold value will be used for the label, eg if level 2 (also level 3 will be reported as met level 2) ### the label on the output will be the label from the chosen threshold -MCRITs_def4 <- MCRITs_def3 %>% +MCRITs_def4 <- MCRITs_def3 |> filter(CRITn == level_threshold) ### convert dataframe into label_map that can be used with the a_freq_j afun function -xlabel_map <- MCRITs_def4 %>% - rename(var = VARNAME, label = CRITx) %>% +xlabel_map <- MCRITs_def4 |> + rename(var = VARNAME, label = CRITx) |> mutate( var = stringr::str_replace(var, "MLx", "MNx"), value = "Y" - ) %>% + ) |> select(PARAMCD, var, value, label) #### extend xlabel_map to include both MCRIT1 and MCRIT2 for all parameters -params <- unique(xlabel_map %>% select(PARAMCD, var, value)) %>% +params <- unique(xlabel_map |> select(PARAMCD, var, value)) |> tidyr::expand(PARAMCD, var, value) -xlabel_map <- params %>% - left_join(., xlabel_map) %>% +xlabel_map <- params |> + left_join(xlabel_map) |> mutate( label = case_when( is.na(label) ~ "TO BE DELETED", @@ -156,8 +160,14 @@ xlabel_map$label_short <- stringr::str_split_i( # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> select(STUDYID, USUBJID, all_of(c(popfl, trtvar))) adsl$colspan_trt <- factor( @@ -181,8 +191,7 @@ ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) adlb_complete <- adlb_jnj - -adlb00 <- adlb_complete %>% +adlb00 <- adlb_complete |> select( USUBJID, AVISITN, @@ -194,8 +203,8 @@ adlb00 <- adlb_complete %>% TRTEMFL, LVOTFL, AVAL - ) %>% - inner_join(adsl) %>% + ) |> + inner_join(adsl) |> relocate( USUBJID, AVISITN, @@ -210,7 +219,6 @@ adlb00 <- adlb_complete %>% LVOTFL ) - ### previous actions on adlb lost the label of variables adlb00 <- var_relabel_list(adlb00, var_labels(adlb_complete, fill = T)) @@ -218,9 +226,9 @@ adlb00 <- var_relabel_list(adlb00, var_labels(adlb_complete, fill = T)) ### data preparation -filtered_adlb_0 <- adlb00 %>% - filter(PARAMCD %in% unique(MCRITs_def3$PARAMCD)) %>% - filter(toupper(PARCAT1) == "CHEMISTRY") %>% +filtered_adlb_0 <- adlb00 |> + filter(PARAMCD %in% unique(MCRITs_def3$PARAMCD)) |> + filter(toupper(PARCAT1) == "CHEMISTRY") |> select( USUBJID, AVISITN, @@ -241,13 +249,12 @@ filtered_adlb_0 <- adlb00 %>% MCRIT2, ANL04FL, ANL05FL - ) %>% + ) |> inner_join(adsl) - -filtered_adlb_1 <- filtered_adlb_0 # %>% -# ## On treatment -# filter(ONTRTFL == "Y") +filtered_adlb_1 <- filtered_adlb_0 |> + ## On treatment + filter(ONTRTFL == "Y") ### Note on On-treatment ### note: by filter ANL04FL/ANL05FL, this table is restricted to On-treatment values, per definition of ANL04FL/ANL05FL @@ -257,13 +264,13 @@ filtered_adlb_1 <- filtered_adlb_0 # %>% ### as mixing worst with other period is not giving the proper selection !!! if (toupper(last_any) == "ANY") { - filtered_adlb_1 <- filtered_adlb_1 %>% + filtered_adlb_1 <- filtered_adlb_1 |> ## Optional : Any : ensure to have one record per subject for direction filter(ANL04FL == "Y" | ANL05FL == "Y") } if (toupper(last_any) == "LAST") { - filtered_adlb_1 <- filtered_adlb_1 %>% + filtered_adlb_1 <- filtered_adlb_1 |> ## Optional : last on treatment record only filter(LVOTFL == "Y") } @@ -271,7 +278,7 @@ if (toupper(last_any) == "LAST") { #### DO NOT USE TRTEMFL = Y in filter, as this will remove subjects from both numerator and denominator #### instead : set MCRIT1MN to a non-reportable value (ie Level 0) and keep in dataset if (trtemfl) { - filtered_adlb_1 <- filtered_adlb_1 %>% + filtered_adlb_1 <- filtered_adlb_1 |> mutate( MCRIT1MN = case_when( !is.na(MCRIT1MN) & is.na(TRTEMFL) | TRTEMFL != "Y" ~ 0, @@ -293,37 +300,39 @@ if (trtemfl) { } -filtered_adlb_1 <- filtered_adlb_1 %>% +filtered_adlb_1 <- filtered_adlb_1 |> mutate( MCRIT1MLx = case_when( - !is.na(MCRIT1ML) ~ paste0( - "(", - stringr::str_split_i(MCRIT1ML, stringr::fixed("("), 2) - ), + !is.na(MCRIT1ML) ~ + paste0( + "(", + stringr::str_split_i(MCRIT1ML, stringr::fixed("("), 2) + ), TRUE ~ NA ) - ) %>% + ) |> mutate( MCRIT1MLx = case_when( !is.na(MCRIT1ML) ~ paste(MCRIT1, MCRIT1MLx), TRUE ~ NA ) - ) %>% + ) |> mutate( MCRIT2MLx = case_when( - !is.na(MCRIT2ML) ~ paste0( - "(", - stringr::str_split_i(MCRIT2ML, stringr::fixed("("), 2) - ), + !is.na(MCRIT2ML) ~ + paste0( + "(", + stringr::str_split_i(MCRIT2ML, stringr::fixed("("), 2) + ), TRUE ~ NA ) - ) %>% + ) |> mutate( MCRIT2MLx = case_when( !is.na(MCRIT2ML) ~ paste(MCRIT2, MCRIT2MLx), TRUE ~ NA ) - ) %>% + ) |> relocate( USUBJID, AVISITN, @@ -342,7 +351,7 @@ filtered_adlb_1 <- filtered_adlb_1 %>% ) -filtered_adlb_1 <- filtered_adlb_1 %>% +filtered_adlb_1 <- filtered_adlb_1 |> mutate( MCRIT1MNx = case_when( MCRIT1MN >= as.numeric(level_threshold) ~ "Y", @@ -352,44 +361,45 @@ filtered_adlb_1 <- filtered_adlb_1 %>% MCRIT2MN >= as.numeric(level_threshold) ~ "Y", !is.na(MCRIT2) ~ "N" ) - ) %>% + ) |> mutate( MCRIT1MNx = factor(MCRIT1MNx, levels = c("Y", "N")), MCRIT2MNx = factor(MCRIT2MNx, levels = c("Y", "N")) ) -paramcd_param <- unique(filtered_adlb_1 %>% select(PARAMCD, PARAM)) +paramcd_param <- unique(filtered_adlb_1 |> select(PARAMCD, PARAM)) -xlabel_map <- xlabel_map %>% - right_join(., paramcd_param) %>% +xlabel_map <- xlabel_map |> + right_join(paramcd_param) |> arrange(PARAM, var) ### to resolve a problem with HDL -- get from the data what MCRIT1 and MCRIT2 are being used xlabel_map_data <- unique( - filtered_adlb_1 %>% - select(PARAMCD, PARAM, MCRIT1, MCRIT2) %>% + filtered_adlb_1 |> + select(PARAMCD, PARAM, MCRIT1, MCRIT2) |> tidyr::pivot_longer(cols = (c("MCRIT1", "MCRIT2"))) -) %>% +) |> mutate( label_short_data = case_when( is.na(value) ~ "TO BE DELETED", TRUE ~ value ), var = paste0(name, "MNx") - ) %>% + ) |> select(PARAMCD, PARAM, var, label_short_data) ## actual fix for HDL female -xlabel_map <- xlabel_map %>% - right_join(., xlabel_map_data) %>% - arrange(PARAM, var) %>% +xlabel_map <- xlabel_map |> + right_join(xlabel_map_data) |> + arrange(PARAM, var) |> ## actual fix for not including HDL female if not derived on data mutate( label = case_when( label_short_data == "TO BE DELETED" & - label != "TO BE DELETED" ~ "TO BE DELETED", + label != "TO BE DELETED" ~ + "TO BE DELETED", TRUE ~ label ) ) @@ -406,27 +416,33 @@ extra_args_rr <- list( ref_path = ref_path ) -lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% +lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> ### first columns split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> split_cols_by(trtvar) +} + +lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", split_fun = remove_split_levels(ctrl_grp) - ) %>% + ) |> split_rows_by( "PARCAT3", - label_pos = "topleft", - child_labels = "visible", - split_label = "Laboratory Category", - split_fun = drop_split_levels, - section_div = " " - ) %>% + label_pos = "hidden", + child_labels = "hidden", + section_div = " ", + split_fun = drop_split_levels + ) |> split_rows_by( "PARAM", label_pos = "topleft", @@ -437,7 +453,7 @@ lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% ", n (%)" ), split_fun = drop_split_levels - ) %>% + ) |> # denominators are varying per test, therefor show denom (not yet in shell) analyze( c("MCRIT1MNx", "MCRIT2MNx"), @@ -453,7 +469,7 @@ lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% indent_mod = 0L ) -result <- build_table(lyt, filtered_adlb_1, alt_counts_df = adsl) +result <- build_table(lyt, filtered_adlb_1, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: @@ -463,8 +479,8 @@ result <- build_table(lyt, filtered_adlb_1, alt_counts_df = adsl) ### Issue: tests with only 1 direction (either low or high) get a line with label a_freq_j (analyze function) ### remove these lines here, as well as lines with label TO BE DELETED -result <- result %>% - prune_table(prune_func = keep_rows(keep_non_null_rows)) %>% +result <- result |> + prune_table(prune_func = keep_rows(keep_non_null_rows)) |> prune_table(prune_func = remove_rows(removerowtext = "TO BE DELETED")) ################################################################################ @@ -477,12 +493,13 @@ result <- remove_col_count(result) # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 27, 27, 27, 35, 37) + +colwidth <- c(64, 27, 27, 27, 27, 33, 33) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab04b.R b/tests/testthat/source_code/tsflab04b.R index 998ec680..3378738c 100644 --- a/tests/testthat/source_code/tsflab04b.R +++ b/tests/testthat/source_code/tsflab04b.R @@ -1,24 +1,4 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab04b -## R version: 4.2.1 -## Short Description: Program to create tsflab04b: -## Subjects With [Last/Any] On-treatment -## Hematology Values [= Level 2] Criteria -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab04b.rtf -## Remarks: Should only be used when abnormalities are based upon markedly abnormal file -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - +#### BEFORE YOU START USING THIS PROGRAM ENSURE THE FOLLOWING: For your trial you should EITHER use lab toxicity grading (lbtoxgrade file) or Abnormality criteria (markedly abnormal file) ################################################################################ # Prep Environment ################################################################################ @@ -37,16 +17,38 @@ test_stop <- FALSE #### !!!! set to FALSE for actual study!! tblid <- "TSFLAB04b" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) popfl <- "SAFFL" + trtvar <- "TRT01A" + ctrl_grp <- "Placebo" +# Add Active Study Agent Combined column +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + level_threshold <- "2" ## For analysis on SI units: use adlb dataset @@ -68,76 +70,73 @@ trtemfl <- TRUE ################################################################################ adlb_complete <- adlb_jnj - ################################################################################ # Retrieve markedly abnormal values from spreadsheet: ################################################################################ ### Markedly Abnormal spreadsheet -markedlyabnormal_file <- file.path(datapath, "markedlyabnormal.xlsx") - - +markedlyabnormal_file <- read_path(datapath, "markedlyabnormal.xlsx") +markedlyabnormal_sheets <- readxl::excel_sheets(markedlyabnormal_file) lbmarkedlyabnormal_defs <- readxl::read_excel( markedlyabnormal_file, sheet = toupper(ad_domain) -) %>% +) |> filter(PARAMCD != "Parameter Code") MCRITs <- unique( - lbmarkedlyabnormal_defs %>% - filter(!stringr::str_ends(VARNAME, "ML")) %>% + lbmarkedlyabnormal_defs |> + filter(!stringr::str_ends(VARNAME, "ML")) |> pull(VARNAME) ) MCRITs_def <- unique( - lbmarkedlyabnormal_defs %>% - filter(VARNAME %in% MCRITs) %>% + lbmarkedlyabnormal_defs |> + filter(VARNAME %in% MCRITs) |> select(PARAMCD, VARNAME, CRIT, SEX) -) %>% - mutate(VARNAME = paste0(VARNAME, "ML")) %>% +) |> + mutate(VARNAME = paste0(VARNAME, "ML")) |> rename(CRITNAME = CRIT) -MCRITs_def2 <- lbmarkedlyabnormal_defs %>% +MCRITs_def2 <- lbmarkedlyabnormal_defs |> filter(VARNAME %in% paste0(MCRITs, "ML")) -MCRITs_def3 <- MCRITs_def2 %>% - left_join(., MCRITs_def, relationship = "many-to-one") %>% +MCRITs_def3 <- MCRITs_def2 |> + left_join(MCRITs_def, relationship = "many-to-one") |> mutate( CRITx = paste0("(", stringr::str_split_i(CRIT, stringr::fixed("("), 2)) - ) %>% - mutate(CRITx = paste(CRITNAME, CRITx)) %>% - select(PARAMCD, SEX, VARNAME, CRITx, ORDER) %>% - mutate(VARNAME = paste0(VARNAME, "x")) %>% + ) |> + mutate(CRITx = paste(CRITNAME, CRITx)) |> + select(PARAMCD, SEX, VARNAME, CRITx, ORDER) |> + mutate(VARNAME = paste0(VARNAME, "x")) |> mutate(CRITn = as.character(4 - as.numeric(ORDER))) ### the threshold value will be used for the label, eg if level 2 (also level 3 will be reported as met level 2) ### the label on the output will be the label from the chosen threshold -MCRITs_def4 <- MCRITs_def3 %>% +MCRITs_def4 <- MCRITs_def3 |> filter(CRITn == level_threshold) ### convert dataframe into label_map that can be used with the a_freq_j afun function -xlabel_map <- MCRITs_def4 %>% - rename(var = VARNAME, label = CRITx) %>% +xlabel_map <- MCRITs_def4 |> + rename(var = VARNAME, label = CRITx) |> mutate( var = stringr::str_replace(var, "MLx", "MNx"), value = "Y" - ) %>% + ) |> select(PARAMCD, var, value, label) - #### extend xlabel_map to include both MCRIT1 and MCRIT2 for all parameters -params <- unique(xlabel_map %>% select(PARAMCD, var, value)) %>% +params <- unique(xlabel_map |> select(PARAMCD, var, value)) |> tidyr::expand(PARAMCD, var, value) -xlabel_map <- params %>% - left_join(., xlabel_map) %>% +xlabel_map <- params |> + left_join(xlabel_map) |> mutate( label = case_when( is.na(label) ~ "TO BE DELETED", @@ -154,13 +153,12 @@ xlabel_map$label_short <- stringr::str_split_i( 1 ) - #### extend xlabel_map to include both MCRIT1 and MCRIT2 for all parameters -params <- unique(xlabel_map %>% select(PARAMCD, var, value)) %>% +params <- unique(xlabel_map |> select(PARAMCD, var, value)) |> tidyr::expand(PARAMCD, var, value) -xlabel_map <- params %>% - left_join(., xlabel_map) %>% +xlabel_map <- params |> + left_join(xlabel_map) |> mutate( label = case_when( is.na(label) ~ "TO BE DELETED", @@ -181,8 +179,14 @@ xlabel_map$label_short <- stringr::str_split_i( # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> select(STUDYID, USUBJID, all_of(c(popfl, trtvar))) adsl$colspan_trt <- factor( @@ -203,9 +207,7 @@ colspan_trt_map <- create_colspan_map( ) ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) -adlb_complete <- adlb_jnj - -adlb00 <- adlb_complete %>% +adlb00 <- adlb_complete |> select( USUBJID, AVISITN, @@ -217,8 +219,8 @@ adlb00 <- adlb_complete %>% TRTEMFL, LVOTFL, AVAL - ) %>% - inner_join(adsl) %>% + ) |> + inner_join(adsl) |> relocate( USUBJID, AVISITN, @@ -240,9 +242,9 @@ adlb00 <- var_relabel_list(adlb00, var_labels(adlb_complete, fill = T)) ### data preparation -filtered_adlb_0 <- adlb00 %>% - filter(PARAMCD %in% unique(MCRITs_def3$PARAMCD)) %>% - filter(toupper(PARCAT1) == "HEMATOLOGY") %>% +filtered_adlb_0 <- adlb00 |> + filter(PARAMCD %in% unique(MCRITs_def3$PARAMCD)) |> + filter(toupper(PARCAT1) == "HEMATOLOGY") |> select( USUBJID, AVISITN, @@ -263,13 +265,13 @@ filtered_adlb_0 <- adlb00 %>% MCRIT2, ANL04FL, ANL05FL - ) %>% + ) |> inner_join(adsl) -filtered_adlb_1 <- filtered_adlb_0 # %>% -# ## On treatment -# filter(ONTRTFL == "Y") +filtered_adlb_1 <- filtered_adlb_0 |> + ## On treatment + filter(ONTRTFL == "Y") ### Note on On-treatment ### note: by filter ANL04FL/ANL05FL, this table is restricted to On-treatment values, per definition of ANL04FL/ANL05FL @@ -279,13 +281,13 @@ filtered_adlb_1 <- filtered_adlb_0 # %>% ### as mixing worst with other period is not giving the proper selection !!! if (toupper(last_any) == "ANY") { - filtered_adlb_1 <- filtered_adlb_1 %>% + filtered_adlb_1 <- filtered_adlb_1 |> ## Optional : Any : ensure to have one record per subject for direction filter(ANL04FL == "Y" | ANL05FL == "Y") } if (toupper(last_any) == "LAST") { - filtered_adlb_1 <- filtered_adlb_1 %>% + filtered_adlb_1 <- filtered_adlb_1 |> ## Optional : last on treatment record only filter(LVOTFL == "Y") } @@ -293,7 +295,7 @@ if (toupper(last_any) == "LAST") { #### DO NOT USE TRTEMFL = Y in filter, as this will remove subjects from both numerator and denominator #### instead : set MCRIT1MN to a non-reportable value (ie Level 0) and keep in dataset if (trtemfl) { - filtered_adlb_1 <- filtered_adlb_1 %>% + filtered_adlb_1 <- filtered_adlb_1 |> mutate( MCRIT1MN = case_when( !is.na(MCRIT1MN) & is.na(TRTEMFL) | TRTEMFL != "Y" ~ 0, @@ -315,37 +317,39 @@ if (trtemfl) { } -filtered_adlb_1 <- filtered_adlb_1 %>% +filtered_adlb_1 <- filtered_adlb_1 |> mutate( MCRIT1MLx = case_when( - !is.na(MCRIT1ML) ~ paste0( - "(", - stringr::str_split_i(MCRIT1ML, stringr::fixed("("), 2) - ), + !is.na(MCRIT1ML) ~ + paste0( + "(", + stringr::str_split_i(MCRIT1ML, stringr::fixed("("), 2) + ), TRUE ~ NA ) - ) %>% + ) |> mutate( MCRIT1MLx = case_when( !is.na(MCRIT1ML) ~ paste(MCRIT1, MCRIT1MLx), TRUE ~ NA ) - ) %>% + ) |> mutate( MCRIT2MLx = case_when( - !is.na(MCRIT2ML) ~ paste0( - "(", - stringr::str_split_i(MCRIT2ML, stringr::fixed("("), 2) - ), + !is.na(MCRIT2ML) ~ + paste0( + "(", + stringr::str_split_i(MCRIT2ML, stringr::fixed("("), 2) + ), TRUE ~ NA ) - ) %>% + ) |> mutate( MCRIT2MLx = case_when( !is.na(MCRIT2ML) ~ paste(MCRIT2, MCRIT2MLx), TRUE ~ NA ) - ) %>% + ) |> relocate( USUBJID, AVISITN, @@ -364,7 +368,7 @@ filtered_adlb_1 <- filtered_adlb_1 %>% ) -filtered_adlb_1 <- filtered_adlb_1 %>% +filtered_adlb_1 <- filtered_adlb_1 |> mutate( MCRIT1MNx = case_when( MCRIT1MN >= as.numeric(level_threshold) ~ "Y", @@ -374,44 +378,45 @@ filtered_adlb_1 <- filtered_adlb_1 %>% MCRIT2MN >= as.numeric(level_threshold) ~ "Y", !is.na(MCRIT2) ~ "N" ) - ) %>% + ) |> mutate( MCRIT1MNx = factor(MCRIT1MNx, levels = c("Y", "N")), MCRIT2MNx = factor(MCRIT2MNx, levels = c("Y", "N")) ) -paramcd_param <- unique(filtered_adlb_1 %>% select(PARAMCD, PARAM)) +paramcd_param <- unique(filtered_adlb_1 |> select(PARAMCD, PARAM)) -xlabel_map <- xlabel_map %>% - right_join(., paramcd_param) %>% +xlabel_map <- xlabel_map |> + right_join(paramcd_param) |> arrange(PARAM, var) ### to resolve a problem with HDL -- get from the data what MCRIT1 and MCRIT2 are being used xlabel_map_data <- unique( - filtered_adlb_1 %>% - select(PARAMCD, PARAM, MCRIT1, MCRIT2) %>% + filtered_adlb_1 |> + select(PARAMCD, PARAM, MCRIT1, MCRIT2) |> tidyr::pivot_longer(cols = (c("MCRIT1", "MCRIT2"))) -) %>% +) |> mutate( label_short_data = case_when( is.na(value) ~ "TO BE DELETED", TRUE ~ value ), var = paste0(name, "MNx") - ) %>% + ) |> select(PARAMCD, PARAM, var, label_short_data) ## actual fix for HDL female -xlabel_map <- xlabel_map %>% - right_join(., xlabel_map_data) %>% - arrange(PARAM, var) %>% +xlabel_map <- xlabel_map |> + right_join(xlabel_map_data) |> + arrange(PARAM, var) |> ## actual fix for not including HDL female if not derived on data mutate( label = case_when( label_short_data == "TO BE DELETED" & - label != "TO BE DELETED" ~ "TO BE DELETED", + label != "TO BE DELETED" ~ + "TO BE DELETED", TRUE ~ label ) ) @@ -429,27 +434,33 @@ extra_args_rr2 <- list( ) -lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% +lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> ### first columns split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> split_cols_by(trtvar) +} + +lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", split_fun = remove_split_levels(ctrl_grp) - ) %>% + ) |> split_rows_by( "PARCAT3", - label_pos = "topleft", - child_labels = "visible", - split_label = "Laboratory Category", - split_fun = drop_split_levels, - section_div = " " - ) %>% + label_pos = "hidden", + child_labels = "hidden", + section_div = " ", + split_fun = drop_split_levels + ) |> split_rows_by( "PARAM", label_pos = "topleft", @@ -460,7 +471,7 @@ lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% ", n (%)" ), split_fun = drop_split_levels - ) %>% + ) |> # denominators are varying per test, therefor show denom (not yet in shell) analyze( c("MCRIT1MNx", "MCRIT2MNx"), @@ -476,7 +487,7 @@ lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% indent_mod = 0L ) -result <- build_table(lyt, filtered_adlb_1, alt_counts_df = adsl) +result <- build_table(lyt, filtered_adlb_1, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: @@ -486,8 +497,8 @@ result <- build_table(lyt, filtered_adlb_1, alt_counts_df = adsl) ### Issue: tests with only 1 direction (either low or high) get a line with label a_freq_j (analyze function) ### remove these lines here, as well as lines with label TO BE DELETED -result <- result %>% - prune_table(prune_func = keep_rows(keep_non_null_rows)) %>% +result <- result |> + prune_table(prune_func = keep_rows(keep_non_null_rows)) |> prune_table(prune_func = remove_rows(removerowtext = "TO BE DELETED")) ################################################################################ @@ -500,12 +511,13 @@ result <- remove_col_count(result) # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(51, 27, 27, 27, 33, 35) + +colwidth <- c(52, 27, 27, 27, 27, 33, 33) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab05.R b/tests/testthat/source_code/tsflab05.R index e02b315c..4001a66c 100644 --- a/tests/testthat/source_code/tsflab05.R +++ b/tests/testthat/source_code/tsflab05.R @@ -1,24 +1,4 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab05 -## R version: 4.2.1 -## Short Description: Program to create tsflab05: -## Subjects With [Last/Any] On-treatment -## Hematology Values [= Level 2] Criteria -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab05.rtf -## Remarks: Should only be used when abnormalities are based upon lab toxicity file -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - +#### BEFORE YOU START USING THIS PROGRAM ENSURE THE FOLLOWING: For your trial you should EITHER use lab toxicity grading (lbtoxgrade file) or Abnormality criteria (markedly abnormal file) ################################################################################ # Prep Environment ################################################################################ @@ -34,17 +14,40 @@ library(junco) ################################################################################ tblid <- "TSFLAB05" -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) fileid <- write_path(opath, tblid) +# Population flag (default=SAFFL). popfl <- "SAFFL" + +# Actual treatment variable (default=TRT01A). trtvar <- "TRT01A" + ctrl_grp <- "Placebo" +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + grade_threshold <- "2" ## For toxicity grades, the units should not matter, work with adlb dataset as default @@ -60,34 +63,17 @@ last_any <- "ANY" ## if the option TRTEMFL needs to be added to the TLF -- ensure the same setting as in tsflabxxxx trtemfl <- TRUE -## parcat5 and 6 options : - -availparcat56 <- c( - "Investigations", - "Metabolism and nutritional disorders", - "Renal and urinary disorders", - "Blood and lymphatic system disorders" -) - -## resrict to some -selparcat56 <- availparcat56[c(1, 2, 4)] - -## get all -selparcat56 <- availparcat56 - ################################################################################ # Initial processing of data ################################################################################ adlb_complete <- adlb_jnj - - ################################################################################ # Process lab toxicity file ################################################################################ -lbtoxgrade_file <- file.path(datapath, "lbtoxgrade.xlsx") +lbtoxgrade_file <- read_path(datapath, "lbtoxgrade.xlsx") lbtoxgrade_sheets <- readxl::excel_sheets(path = lbtoxgrade_file) ### CTC5 or DAIDS21c : default CTC5 @@ -98,18 +84,17 @@ lbtoxgrade_defs <- readxl::read_excel(lbtoxgrade_file, sheet = "CTC5") lbtoxgrade_defs <- unique( unique( - lbtoxgrade_defs %>% + lbtoxgrade_defs |> select(all_of(lbvars), TOXTERM, TOXGRD, INDICATR) - ) %>% + ) |> mutate( ATOXDSCLH = TOXTERM, ATOXGRLH = paste("Grade", TOXGRD) - ) %>% - rename(ATOXDIR = INDICATR) %>% + ) |> + rename(ATOXDIR = INDICATR) |> select(all_of(lbvars), ATOXDSCLH, ATOXDIR) ) - ################################################################################ # Initial processing of data ################################################################################ @@ -117,66 +102,69 @@ lbtoxgrade_defs <- unique( ### be aware, there are toxicity terms that are based upon diff tests (example "Neutrophil Count Decreased": NEUT and NEUTSG) !!!!! ### if both tests are included in ADaM dataset, review your derivations carefully attention_terms <- - unique(lbtoxgrade_defs %>% select(ATOXDSCLH, all_of(lbvars))) %>% - group_by(ATOXDSCLH) %>% - mutate(n = n_distinct(LBTESTCD)) %>% + unique(lbtoxgrade_defs |> select(ATOXDSCLH, all_of(lbvars))) |> + group_by(ATOXDSCLH) |> + mutate(n = n_distinct(LBTESTCD)) |> filter(n > 1) ad_toxterms <- bind_rows( unique( - adlb_complete %>% - select(PARAMCD, ATOXDSCL) %>% + adlb_complete |> + select(PARAMCD, ATOXDSCL) |> mutate(TOXTERM = ATOXDSCL, TOXDIR = "LOW") ), unique( - adlb_complete %>% - select(PARAMCD, ATOXDSCH) %>% + adlb_complete |> + select(PARAMCD, ATOXDSCH) |> mutate(TOXTERM = ATOXDSCH, TOXDIR = "HIGH") ) -) %>% - select(PARAMCD, TOXTERM, TOXDIR) %>% - filter(!is.na(TOXTERM)) %>% +) |> + select(PARAMCD, TOXTERM, TOXDIR) |> + filter(!is.na(TOXTERM)) |> arrange(TOXTERM, TOXDIR, PARAMCD) - -attention_ad_toxterms <- ad_toxterms %>% - group_by(TOXTERM) %>% - mutate(n = n_distinct(PARAMCD)) %>% +attention_ad_toxterms <- ad_toxterms |> + group_by(TOXTERM) |> + mutate(n = n_distinct(PARAMCD)) |> filter(n > 1) #### From here onwards: avoid using PARAMCD, to ensure toxterm is combined - ### could also work with param_lookup and lbtoxgrade_defs ### ALERT: do not include PARAMCD here as some toxicity terms are based on more than one PARAMCD: here : NEUT and NEUTSG both have TOXTERM = Neutrophil Count Decreased toxterms <- unique( - adlb_complete %>% - filter(!(is.na(ATOXDSCL) & is.na(ATOXDSCH))) %>% + adlb_complete |> + filter(!(is.na(ATOXDSCL) & is.na(ATOXDSCH))) |> ### do not include PARAMCD here!!!! - select(ATOXDSCL, ATOXDSCH) %>% + select(ATOXDSCL, ATOXDSCH) |> tidyr::pivot_longer( - ., cols = c("ATOXDSCL", "ATOXDSCH"), names_to = "VARNAME", values_to = "ATOXDSCLH" ) -) %>% +) |> filter(!is.na(ATOXDSCLH)) ### convert dataframe into label_map that can be used with the a_freq_j afun function -xlabel_map <- toxterms %>% +xlabel_map <- toxterms |> mutate( var = "ATOXGRLHx", value = "Y", label = as.character(ATOXDSCLH) - ) %>% + ) |> select(ATOXDSCLH, value, label) ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> select(STUDYID, USUBJID, all_of(c(popfl, trtvar))) adsl$colspan_trt <- factor( @@ -199,7 +187,7 @@ colspan_trt_map <- create_colspan_map( ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) flagvars <- c("ONTRTFL", "TRTEMFL", "LVOTFL") -adlb00 <- adlb_complete %>% +adlb00 <- adlb_complete |> select( USUBJID, AVISITN, @@ -211,14 +199,13 @@ adlb00 <- adlb_complete %>% LBSEQ, AVAL, AVALC - ) %>% - inner_join(adsl) %>% + ) |> + inner_join(adsl) |> mutate( ATOXGRL = as.character(ATOXGRL), ATOXGRH = as.character(ATOXGRH) - ) %>% + ) |> relocate( - ., USUBJID, ANL04FL, ANL05FL, @@ -234,38 +221,18 @@ adlb00 <- adlb_complete %>% AVAL ) - -# adlb00 <- adlb00 #%>% -## APT comment on PARCAT6 : -## HGB and WBC : Set to "Blood and lymphatic system disorders". -## HGB and WBC parameter are in 2 categories, one for the high and another one for the low direction grading. -## Anemia (HGB low) and Leukocytosis (WBC high) are in the category "Blood and lymphatic system disorders". -## The grading in the opposite directions are categorized under "Investigations". -## Therefor, both PARCAT5 and PARCAT6 are populated for HGB abd WBC. -## Deal with what is needed at later level, when we have splitted low and high - -# obj_label(adlb00$PARCAT56) <- "Combined PARCAT56" - ### important: previous actions lost the label of variables - -adlb00 <- var_relabel_list(adlb00, var_labels(adlb_complete, fill = T)) - -if (all(selparcat56 != "")) { - filtered_adlb <- adlb00 %>% - filter((PARCAT5 %in% selparcat56) | (PARCAT6 %in% selparcat56)) -} else { - filtered_adlb <- adlb00 -} +filtered_adlb <- var_relabel_list(adlb00, var_labels(adlb_complete, fill = T)) ### low grades : ATOXDSCL ATOXGRL ANL04FL -filtered_adlb_low <- filtered_adlb %>% - filter(!is.na(ATOXDSCL) & !is.na(ATOXGRL)) %>% +filtered_adlb_low <- filtered_adlb |> + filter(!is.na(ATOXDSCL) & !is.na(ATOXGRL)) |> mutate( ATOXDSCLH = ATOXDSCL, ATOXGRLH = ATOXGRL, ATOXDIR = "LOW", ANL045FL = ANL04FL - ) %>% + ) |> select( USUBJID, starts_with("PAR"), @@ -277,18 +244,18 @@ filtered_adlb_low <- filtered_adlb %>% LBSEQ, AVAL, AVALC - ) %>% + ) |> select(-c(ATOXGRL, ATOXGRH, ATOXDSCL, ATOXDSCH)) ### high grades: ATOXDSCH ATOXGRH ANL05FL -filtered_adlb_high <- filtered_adlb %>% - filter(ANL05FL == "Y" & !is.na(ATOXDSCH) & !is.na(ATOXGRH)) %>% +filtered_adlb_high <- filtered_adlb |> + filter(!is.na(ATOXDSCH) & !is.na(ATOXGRH)) |> mutate( ATOXDSCLH = ATOXDSCH, ATOXGRLH = ATOXGRH, ATOXDIR = "HIGH", ANL045FL = ANL05FL - ) %>% + ) |> select( USUBJID, starts_with("PAR"), @@ -300,7 +267,7 @@ filtered_adlb_high <- filtered_adlb %>% LBSEQ, AVAL, AVALC - ) %>% + ) |> select(-c(ATOXGRL, ATOXGRH, ATOXDSCL, ATOXDSCH)) @@ -309,40 +276,18 @@ filtered_adlb_tox <- bind_rows( filtered_adlb_low, filtered_adlb_high - ) %>% - select(-c(ATOXGR, ATOXGRN)) %>% - mutate(ATOXGRLHN = as.numeric(ATOXGRLH)) %>% + ) |> + select(-c(ATOXGR, ATOXGRN)) |> + mutate(ATOXGRLHN = as.numeric(ATOXGRLH)) |> inner_join(adsl) - -### correction of proper category (PARCAT56) for HGB (LOW) and WBC (HIGH) -filtered_adlb_tox <- - filtered_adlb_tox %>% - mutate( - PARCAT56 = case_when( - PARAMCD == "HGB" & ATOXDIR == "LOW" ~ PARCAT6, - PARAMCD == "WBC" & ATOXDIR == "HIGH" ~ PARCAT6, - TRUE ~ PARCAT5 - ) - ) %>% - mutate( - PARCAT56 = factor( - PARCAT56, - levels = unique(c( - "Blood and lymphatic system disorders", - levels(adlb_complete$PARCAT5) - )) - ) - ) - - filtered_adlb_tox <- unique( filtered_adlb_tox ) -filtered_adlb_tox_1 <- filtered_adlb_tox # %>% -# ## On treatment -# filter(ONTRTFL == "Y") +filtered_adlb_tox_1 <- filtered_adlb_tox |> + ## On treatment + filter(ONTRTFL == "Y") ### Note on On-treatment ### note: by filter ANL04FL/ANL05FL, this table is restricted to On-treatment values, per definition of ANL04FL/ANL05FL @@ -352,13 +297,13 @@ filtered_adlb_tox_1 <- filtered_adlb_tox # %>% ### as mixing worst with other period is not giving the proper selection !!! if (toupper(last_any) == "ANY") { - filtered_adlb_tox_1 <- filtered_adlb_tox_1 %>% + filtered_adlb_tox_1 <- filtered_adlb_tox_1 |> ## Optional : Any : ensure to have one record per subject for direction filter(ANL04FL == "Y" | ANL05FL == "Y") } if (toupper(last_any) == "LAST") { - filtered_adlb_tox_1 <- filtered_adlb_tox_1 %>% + filtered_adlb_tox_1 <- filtered_adlb_tox_1 |> ## Optional : last on treatment record only filter(LVOTFL == "Y") } @@ -367,7 +312,7 @@ if (toupper(last_any) == "LAST") { #### DO NOT USE TRTEMFL = Y in filter, as this will remove subjects from both numerator and denominator #### instead : set ATOXGRLH to a non-reportable value (ie Grade 0) and keep in dataset if (trtemfl) { - filtered_adlb_tox_1 <- filtered_adlb_tox_1 %>% + filtered_adlb_tox_1 <- filtered_adlb_tox_1 |> mutate( ATOXGRLHN = case_when( is.na(TRTEMFL) | TRTEMFL != "Y" ~ 0, @@ -376,25 +321,32 @@ if (trtemfl) { ) } - -### Alphabetical sorting of toxicity terms -atoxdsclh_levels <- sort(as.character(unique(filtered_adlb_tox_1$ATOXDSCLH))) - -filtered_adlb_tox_1 <- filtered_adlb_tox_1 %>% +### Sorting: alphabetically by base term, LOW before HIGH within same term +atoxdsclh_levels <- filtered_adlb_tox_1 |> + distinct(ATOXDSCLH, ATOXDIR) |> + mutate( + base_term = sub(", (low|high)$", "", ATOXDSCLH, ignore.case = TRUE), + ATOXDIR_ord = factor(ATOXDIR, levels = c("LOW", "HIGH")) + ) |> + arrange(base_term, ATOXDIR_ord) |> + pull(ATOXDSCLH) |> + as.character() + +filtered_adlb_tox_1 <- filtered_adlb_tox_1 |> mutate( ATOXGRLHx = case_when( ATOXGRLHN >= as.numeric(grade_threshold) ~ "Y", TRUE ~ "N" ) - ) %>% - mutate(ATOXGRLHx = factor(ATOXGRLHx, levels = c("Y", "N"))) %>% + ) |> + mutate(ATOXGRLHx = factor(ATOXGRLHx, levels = c("Y", "N"))) |> mutate(ATOXDSCLH = factor(ATOXDSCLH, levels = atoxdsclh_levels)) # check uniqueness -check_non_unique_subject <- filtered_adlb_tox_1 %>% - group_by(USUBJID, ATOXDSCLH) %>% - mutate(n_subject = n()) %>% +check_non_unique_subject <- filtered_adlb_tox_1 |> + group_by(USUBJID, ATOXDSCLH) |> + mutate(n_subject = n()) |> filter(n_subject > 1) if (nrow(check_non_unique_subject)) { @@ -403,11 +355,6 @@ if (nrow(check_non_unique_subject)) { ) } -### syntethic data: no records for NEUT/NEUTSG for the further selection (ATOXGRL is never populated for these records) -xx <- adlb00 %>% - filter(ATOXDSCL == "Neutrophil Count Decreased" & !is.na(ATOXGRL)) - - ################################################################################ # Define layout and build table: ################################################################################ @@ -419,39 +366,37 @@ extra_args_rr <- list( ref_path = ref_path ) - -lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% +lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> ### first columns split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> split_cols_by(trtvar) +} + +lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> split_cols_by( trtvar, labels_var = "rrisk_label", split_fun = remove_split_levels(ctrl_grp) - ) %>% - split_rows_by( - "PARCAT56", - label_pos = "topleft", - child_labels = "visible", - split_label = "Laboratory Category", - split_fun = drop_split_levels, - section_div = " " - ) %>% + ) |> split_rows_by( "ATOXDSCLH", label_pos = "topleft", split_label = paste0( - "Laboratory Test \u2265 Grade ", + "Laboratory Test >= Grade ", grade_threshold, ", n (%)" ), child_labels = "hidden", split_fun = drop_split_levels - ) %>% + ) |> analyze( "ATOXGRLHx", afun = a_freq_j, @@ -466,17 +411,14 @@ lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") %>% indent_mod = 0L ) -result <- build_table(lyt, filtered_adlb_tox_1, alt_counts_df = adsl) +result <- build_table(lyt, filtered_adlb_tox_1, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: # - Remove colcount from rrisk_header ################################################################################ -### Issue: tests with only 1 direction (either low or high) get a line with label a_freq_j (analyze function) -### remove these lines here - -result <- result %>% prune_table(prune_func = keep_rows(keep_non_null_rows)) +result <- result |> prune_table(prune_func = keep_rows(keep_non_null_rows)) ################################################################################ # Remove colcount from rrisk_header: @@ -488,13 +430,14 @@ result <- remove_col_count(result) # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(62, 27, 27, 27, 33, 35) + +colwidth <- c(58, 27, 27, 29, 27, 33, 35) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab06.R b/tests/testthat/source_code/tsflab06.R index 9346cf58..2ff032e6 100644 --- a/tests/testthat/source_code/tsflab06.R +++ b/tests/testthat/source_code/tsflab06.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab06 -## R version: 4.2.1 -## Short Description: Program to create tsflab06: -## Shift in [Chemistry/Hematology] Laboratory Values From Baseline to [Time Point] -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab06.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -34,149 +10,60 @@ library(junco) tblid <- "TSFLAB06" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) popfl <- "SAFFL" + +# Actual treatment variable (default=TRT01A). trtvar <- "TRT01A" + ctrl_grp <- "Placebo" ad_domain <- "ADLB" -## select a Single time point only -selvisit <- c("Cycle 02") - - -### note : this shell covers multiple tables depending on parcat3 selections - -## allowed PARCAT3 selections - -# parcat3sel <- "General chemistry" -# parcat3sel <- "Kidney function" -# parcat3sel <- "Liver biochemistry" -# parcat3sel <- "Lipids" -# -# ### Hematology (HM) : has 3 subcategories that should be included on one table -# parcat3sel <- c("Complete blood count","WBC differential","Coagulation studies") - -# per DPS specifications, the output identifier should include the abbreviation for the category - -# 1. Present laboratory tests using separate outputs for each category as follows: -# General chemistry (GC): Sodium, Potassium, Chloride, Bicarbonate, Urea Nitrogen, Glucose, Calcium, Magnesium, Phosphate, Protein, Albumin, Creatine Kinase, Amylase, Lipase -# Kidney function (KF): Creatinine, GFR from Creatinine -# Liver biochemistry (LV): Alkaline Phosphatase, Alanine Aminotransferase, Aspartate Aminotransferase, Bilirubin, Prothrombin Intl. Normalized Ratio, Gamma Glutamyl Transferase -# Lipids (LP): Cholesterol, HDL Cholesterol, LDL Cholesterol, Triglycerides -# Hematology (HM): Subcategory rows should be included for Complete Blood Count, White Blood Cell Differential and for Coagulation Studies -# Complete blood count: Leukocytes, Hemoglobin, Platelets; -# WBC differential: Lymphocytes, Neutrophils, Eosinophils; -# Coagulation studies: Prothrombin Time, Activated Partial Thromboplastin Time. - -# The output identifier should include the abbreviation for the laboratory category (eg, TSFLAB02GC for General Chemistry) - -# In current template program, only 1 version is created, without the proper abbreviation appended -# The reason for this is that TSFLAB02GC is not included in the DPS system - only the core version TSFLAB02 - -get_abbreviation <- function(parcat3sel) { - parcat3sel <- toupper(parcat3sel) - abbr <- NULL - if (length(parcat3sel) == 1) { - if (parcat3sel == toupper("General chemistry")) { - abbr <- "GC" - } - # the following line should be removed for a true study, global jjcs standards in DPS system does not include the abbreviation - if (parcat3sel == toupper("General chemistry")) { - abbr <- "" - } - # - if (parcat3sel == toupper("Kidney function")) { - abbr <- "KF" - } - if (parcat3sel == toupper("Liver biochemistry")) { - abbr <- "LV" - } - if (parcat3sel == toupper("Lipids")) abbr <- "LP" - } - if (length(parcat3sel) > 1) { - if ( - all( - parcat3sel %in% - toupper(c( - "Complete blood count", - "WBC differential", - "Coagulation studies" - )) - ) - ) { - abbr <- "HM" - } - } - - if (is.null(abbr)) { - message("Incorrect specification of parcat3sel") - } - - abbr -} - -get_tblid <- function(tblid, parcat3sel, method = c("after", "inbetween")) { - abbr <- get_abbreviation(parcat3sel) +## select a Single time point only — set to NULL to include all visits +selvisit <- NULL # c("Cycle 02") - method <- match.arg(method) - # when inbetween, the abbreviation will be added prior to the number part of the table identifier - # when after (default), the abbreviation will be added at the end of the table identifier - - x <- 0 - if (method == "inbetween") { - x <- regexpr(pattern = "[0-9]", tblid)[1] - } - - if (x > 0) { - tblid1 <- substr(tblid, 1, x - 1) - tblid2 <- substring(tblid, x) - tblid_new <- paste0(tblid1, abbr, tblid2) - } else { - tblid_new <- paste0(tblid, abbr) - } - - return(tblid_new) -} +# PARCAT1 categories to produce: CHEMISTRY -> CHM, HEMATOLOGY -> HM +parcat1_categories <- list( + chm = "CHEMISTRY", + hem = "HEMATOLOGY" +) ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select(STUDYID, USUBJID, all_of(c(popfl, trtvar))) - -adsl <- adsl %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> mutate( - colspan_trt = factor( - ifelse(.data[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") ) - ) -## to ensure the same order as on other outputs -trt_order <- as.character((unique( - adsl %>% select("colspan_trt", all_of(trtvar)) -) %>% - arrange(colspan_trt, .data[[trtvar]]))[[trtvar]]) -adsl[[trtvar]] <- factor(as.character(adsl[[trtvar]]), levels = trt_order) - + ) |> + select(STUDYID, USUBJID, all_of(c(popfl, trtvar))) adlb_complete <- adlb_jnj - - flagvars <- c("ONTRTFL", "TRTEMFL", "LVOTFL") -adlb00 <- adlb_complete %>% - filter(ANL02FL == "Y") %>% - filter(!is.na(ANRIND)) %>% - filter(!is.na(BNRIND)) %>% - filter(AVISIT %in% selvisit) %>% +adlb00 <- adlb_complete |> + # Filter to CHEMISTRY and HEMATOLOGY only + filter(toupper(PARCAT1) %in% toupper(unlist(parcat1_categories))) |> + filter(ANL02FL == "Y", if (!is.null(selvisit)) AVISIT %in% selvisit else TRUE) |> + filter(!is.na(ANRIND)) |> + filter(!is.na(BNRIND)) |> + mutate(AVISIT = stringr::str_to_sentence(AVISIT)) |> + mutate( + AVISIT = factor( + .data[["AVISIT"]], + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) |> select( USUBJID, AVISITN, @@ -186,6 +73,7 @@ adlb00 <- adlb_complete %>% PARAMN, PARCAT1, PARCAT3, + PARCAT3N, ANRIND, BNRIND, ANRLO, @@ -197,28 +85,28 @@ adlb00 <- adlb_complete %>% AVALC ) +# Sort by PARCAT1, PARCAT3N, then PARAM alphabetically +adlb00 <- adlb00 |> + arrange(PARCAT1, PARCAT3N, PARCAT3, PARAM) -# ensure sorting on PARAM is alphabetical -params <- sort(unique(as.character(adlb00$PARAM))) +# Set PARAM factor levels in PARCAT1 -> PARCAT3N -> PARAM order +params_ordered <- unique(as.character(adlb00$PARAM)) -adlb00 <- adlb00 %>% - mutate(PARAM = factor(as.character(PARAM), levels = params)) %>% - # single level AVISIT - mutate(AVISIT = factor(as.character(AVISIT))) +adlb00 <- adlb00 |> + mutate(PARAM = factor(as.character(PARAM), levels = params_ordered)) adlb00 <- var_relabel_list(adlb00, var_labels(adlb_complete, fill = T)) -filtered_adlb <- adlb00 %>% - filter(ANL02FL == "Y") %>% - filter(!is.na(ANRIND)) %>% - filter(!is.na(BNRIND)) %>% - filter(AVISIT %in% selvisit) %>% +filtered_adlb <- adlb00 |> + filter(ANL02FL == "Y", if (!is.null(selvisit)) AVISIT %in% selvisit else TRUE) |> + filter(!is.na(ANRIND)) |> + filter(!is.na(BNRIND)) |> inner_join(adsl) ## trick for alt_counts_df to work with col splitting # add BNRIND to adsl, all assign to extra level N (column will be used for N counts) -adslx <- adsl %>% - mutate(BNRIND = "N") %>% +adslx <- adsl |> + mutate(BNRIND = "N") |> mutate( BNRIND = factor( BNRIND, @@ -228,14 +116,14 @@ adslx <- adsl %>% ) ### make factor var and add extra level to BNRIND to be used as N column -filtered_adlb <- filtered_adlb %>% +filtered_adlb <- filtered_adlb |> mutate( BNRIND = factor( as.character(BNRIND), levels = c("N", "LOW", "NORMAL", "HIGH"), labels = c("N", "Low", "Normal", "High") ) - ) %>% + ) |> mutate( ANRIND = factor( as.character(ANRIND), @@ -244,7 +132,6 @@ filtered_adlb <- filtered_adlb %>% ) ) - ## add variable for column split header filtered_adlb$BNRIND_header <- "Baseline" adslx$BNRIND_header <- "Baseline" @@ -252,46 +139,45 @@ adslx$BNRIND_header <- "Baseline" filtered_adlb$BNRIND_header2 <- " " ## first column N should not appear under Baseline column span adslx$BNRIND_header2 <- " " ## first column N should not appear under Baseline column span - ################################################################################ # define a mapping for low/normal/high, tests that do not have both directions are to be identified ################################################################################ low_high_map <- unique( - filtered_adlb %>% + filtered_adlb |> mutate( xANRLO = !is.na(ANRLO), xANRHI = !is.na(ANRHI) - ) %>% - select(PARCAT3, PARAMCD, PARAM, xANRLO, xANRHI) %>% - group_by(PARAMCD) %>% - mutate(xANRLO = any(xANRLO), xANRHI = any(xANRHI)) %>% + ) |> + select(PARCAT1, PARCAT3N, PARCAT3, PARAMCD, PARAM, xANRLO, xANRHI) |> + group_by(PARAMCD) |> + mutate(xANRLO = any(xANRLO), xANRHI = any(xANRHI)) |> ungroup() ) # check if there are tests that only have 1 direction lh_1 <- nrow( - low_high_map %>% + low_high_map |> filter(!(xANRLO & xANRHI)) ) > 0 if (lh_1) { - low_high <- low_high_map %>% - mutate(ANRIND = "LOW") %>% - mutate(ANRIND = factor(ANRIND, levels = c("LOW", "NORMAL", "HIGH"))) %>% - mutate(PARAMCD = droplevels(PARAMCD)) %>% + low_high <- low_high_map |> + mutate(ANRIND = "LOW") |> + mutate(ANRIND = factor(ANRIND, levels = c("LOW", "NORMAL", "HIGH"))) |> + mutate(PARAMCD = droplevels(PARAMCD)) |> tidyr::expand(., PARAMCD, ANRIND) - low_high_map <- low_high_map %>% - full_join(., low_high) %>% + low_high_map <- low_high_map |> + full_join(low_high) |> mutate( todel = case_when( ANRIND == "LOW" & !xANRLO ~ TRUE, ANRIND == "HIGH" & !xANRHI ~ TRUE, TRUE ~ FALSE ) - ) %>% - filter(!todel) %>% + ) |> + filter(!todel) |> select(-c(todel, xANRLO, xANRHI)) } @@ -302,48 +188,40 @@ if (lh_1) { ################################################################################ ################################################################################ -# Core function to produce shell for specific parcat3 selection +# Core function to produce shell for specific parcat1 selection ################################################################################ -build_result_parcat3 <- function( +build_result_parcat1 <- function( df = filtered_adlb, - PARCAT3sel = NULL, + PARCAT1sel = NULL, .adsl = adslx, map = low_high_map, tblid, - save2rtf = TRUE, .trtvar = trtvar ) { - tblidx <- get_tblid(tblid, PARCAT3sel) - titles2 <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" - ) - - lyt_filter <- function(PARCAT3sel = NULL, map) { - if (!is.null(PARCAT3sel)) { - map <- map %>% - filter(PARCAT3 %in% PARCAT3sel) + lyt_filter <- function(PARCAT1sel = NULL, map) { + if (!is.null(PARCAT1sel)) { + map <- map |> + filter(toupper(PARCAT1) %in% toupper(PARCAT1sel)) - df_filtered <- df %>% - filter(PARCAT3 %in% PARCAT3sel) + df_filtered <- df |> + filter(toupper(PARCAT1) %in% toupper(PARCAT1sel)) } else { df_filtered <- df } - lyt <- basic_table(show_colcounts = FALSE) %>% + lyt <- basic_table(show_colcounts = FALSE) |> ## to ensure N column is not under the Baseline column span header - split_cols_by("BNRIND_header2") %>% - split_cols_by("BNRIND", split_fun = keep_split_levels("N")) %>% - split_cols_by("BNRIND_header", nested = FALSE) %>% + split_cols_by("BNRIND_header2") |> + split_cols_by("BNRIND", split_fun = keep_split_levels("N")) |> + split_cols_by("BNRIND_header", nested = FALSE) |> split_cols_by( "BNRIND", split_fun = make_split_fun( pre = list(rm_levels(excl = "N")), post = list(add_overall_facet("TOTAL", "Total")) ) - ) %>% + ) |> #### replace split_rows and summarize by single analyze call ### a_freq_j only works due to ### special arguments can do the trick : denomf = adslx & .stats = count_unique @@ -358,7 +236,7 @@ build_result_parcat3 <- function( extrablankline = TRUE ), indent_mod = -1L - ) %>% + ) |> ## main part of table, restart row-split so nested = FALSE split_rows_by( "PARAM", @@ -368,19 +246,19 @@ build_result_parcat3 <- function( split_label = "Laboratory Test", split_fun = drop_split_levels, section_div = " " - ) %>% + ) |> split_rows_by( "AVISIT", label_pos = "topleft", split_label = "Study Visit", section_div = " " - ) %>% + ) |> split_rows_by( .trtvar, label_pos = "hidden", split_label = "Treatment Group", section_div = " " - ) %>% + ) |> ### a_freq_j ### the special statistic "n_rowdf" option does the trick here of getting the proper value for the N column summarize_row_groups( @@ -390,7 +268,7 @@ build_result_parcat3 <- function( .stats = "n_rowdf", restr_columns = c("N") ) - ) %>% + ) |> ## add extra level TOTAL using new_levels, rather than earlier technique ## advantage for denominator derivation -- n_rowdf can be used, if we'd like to present fraction as well ## switch .stats to count_unique_denom_fraction or count_unique_fraction @@ -410,20 +288,20 @@ build_result_parcat3 <- function( ) } - lyt <- lyt_filter(PARCAT3sel = PARCAT3sel, map = map) + lyt <- lyt_filter(PARCAT1sel = PARCAT1sel, map = map) - if (!is.null(PARCAT3sel)) { - df <- df %>% - filter(PARCAT3 %in% PARCAT3sel) + if (!is.null(PARCAT1sel)) { + df <- df |> + filter(toupper(PARCAT1) %in% toupper(PARCAT1sel)) } if (nrow(df) > 0) { - result <- build_table(lyt, df, alt_counts_df = .adsl) + result <- build_table(lyt, df, alt_counts_df = .adsl, round_type = "sas") } else { result <- NULL message(paste0( - "Parcat3 [", - PARCAT3sel, + "Parcat1 [", + PARCAT1sel, "] is not present on input dataset" )) return(result) @@ -433,72 +311,30 @@ build_result_parcat3 <- function( # Set title ################################################################################ - result <- set_titles(result, titles2) - - if (save2rtf) { - ################################################################################ - # Convert to tbl file and output table - ################################################################################ - ### add the proper abbreviation to the tblid, and add opath path - fileid <- write_path(opath, tblidx) - - tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") - } return(result) } +################################################################################ +# Apply core function: one RTF per PARCAT1 category +# - Chemistry (CHM) +# - Hematology (HM) +# Data sorted by PARCAT1 -> PARCAT3N -> PARAM (alphabetical) +################################################################################ +### note: the same core tblid (TSFLAB06) is used; abbreviation (CHM/HM) is appended via get_tblid +result_chm <- build_result_parcat1( + PARCAT1sel = parcat1_categories[["chm"]], + tblid = tblid +) + ################################################################################ -# Apply core function to all specified levels of parcat3 selection -# - General Chemistry (GC) -# - Kidney Function (KF) -# - Liver Biochemistry (LV) -# - Lipids (LP) -# - Hematology (HM) : -# Complete Blood Count -# WBC Differential -# Coagulation Studies +# Add titles and footnotes: ################################################################################ -### note : the same core tblid (TSFLAB06) will be used for all, inside the core function build_result_parcat3 the proper abbreviation will be added - -### titles will not be retrieved for these, as the table identifiers are not in the DPS system -### study teams will have to ensure all versions that are needed are included in DPS system -# result1 <- build_result_parcat3( -# PARCAT3sel = "Liver biochemistry", -# tblid = tblid, -# save2rtf = TRUE -# ) -# result2 <- build_result_parcat3( -# PARCAT3sel = "Kidney function", -# tblid = tblid, -# save2rtf = TRUE -# ) -# result3 <- build_result_parcat3( -# PARCAT3sel = "Lipids", -# tblid = tblid, -# save2rtf = TRUE -# ) -# -# result4 <- build_result_parcat3( -# PARCAT3sel = c( -# "Complete blood count", -# "WBC differential", -# "Coagulation studies" -# ), -# tblid = tblid, -# save2rtf = TRUE -# ) - -### if a certain category is not present, no rtf will be generated - -result <- build_result_parcat3( - PARCAT3sel = "General chemistry", - tblid = tblid, - save2rtf = FALSE -) -colwidth <- c(42, 7, 5, 7, 5, 7) +colwidth <- c(64, 7, 5, 7, 5, 7) + +result <- set_titles(result_chm, tab_titles) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +tt_to_tlgrtf(colwidths = colwidth, result, file = write_path(opath, tblid), orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab07.R b/tests/testthat/source_code/tsflab07.R index 37f22762..cfdbb2a7 100644 --- a/tests/testthat/source_code/tsflab07.R +++ b/tests/testthat/source_code/tsflab07.R @@ -1,24 +1,4 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsflab07 -## R version: 4.2.1 -## Short Description: Program to create tsflab07: -## Shift in [Chemistry/Hematology] Laboratory Values -## From Baseline to Worst NCI-CTCAE Grade [During Time Period] -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, adlb.RDS or adlbc.RDS -## Output: tsflab07.rtf -## Remarks: Only produce this table if your trial has used lbtoxgrade file for adlb -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - +#### BEFORE YOU START USING THIS PROGRAM ENSURE THE FOLLOWING: For your trial you should EITHER use lab toxicity grading (lbtoxgrade file) or Abnormality criteria (markedly abnormal file) ################################################################################ # Prep Environment ################################################################################ @@ -35,19 +15,28 @@ library(junco) tblid <- "TSFLAB07" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) - -ad_domain <- "ADLB" - popfl <- "SAFFL" + +# Actual treatment variable (default=TRT01A). trtvar <- "TRT01A" + ctrl_grp <- "Placebo" +ad_domain <- "ADLB" + +# Flag variable for worst low toxicity grade (default=ANL04FL). +anl_low_fl <- "ANL04FL" +# Flag variable for worst high toxicity grade (default=ANL05FL). +anl_high_fl <- "ANL05FL" + +# Show percentage alongside count (default=FALSE). +show_pct <- FALSE ################################################################################ # Initial processing of data @@ -55,42 +44,24 @@ ctrl_grp <- "Placebo" adlb_complete <- adlb_jnj - ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select(STUDYID, USUBJID, all_of(c(popfl, trtvar))) - -adsl <- adsl %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> mutate( - colspan_trt = factor( - ifelse(.data[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") ) - ) - -## to ensure the same order as on other outputs -trt_order <- as.character((unique( - adsl %>% select("colspan_trt", all_of(trtvar)) -) %>% - arrange(colspan_trt, .data[[trtvar]]))[[trtvar]]) -adsl[[trtvar]] <- factor(as.character(adsl[[trtvar]]), levels = trt_order) - - -availparcat56 <- c( - "Blood and lymphatic system disorders", - "Investigations", - "Metabolism and nutritional disorders", - "Renal and urinary disorders" -) + ) |> + select(STUDYID, USUBJID, all_of(c(popfl, trtvar))) flagvars <- c("ONTRTFL", "TRTEMFL", "LVOTFL", "ABLFL") -adlb00 <- adlb_complete %>% - filter(!is.na(ATOXGR)) %>% - filter(!is.na(BTOXGR)) %>% +adlb00 <- adlb_complete |> + filter(!is.na(ATOXGR)) |> + filter(!is.na(BTOXGR)) |> select( USUBJID, AVISITN, @@ -100,6 +71,7 @@ adlb00 <- adlb_complete %>% PARAMN, PARCAT1, PARCAT3, + PARCAT4, PARCAT5, PARCAT6, starts_with("ATOX"), @@ -109,13 +81,12 @@ adlb00 <- adlb_complete %>% LBSEQ, AVAL, AVALC - ) %>% - inner_join(adsl) %>% + ) |> + inner_join(adsl) |> relocate( - ., USUBJID, - ANL04FL, - ANL05FL, + all_of(anl_low_fl), + all_of(anl_high_fl), ONTRTFL, TRTEMFL, AVISIT, @@ -132,7 +103,6 @@ adlb00 <- adlb_complete %>% AVAL ) - adlb00 <- var_relabel_list(adlb00, var_labels(adlb_complete, fill = T)) filtered_adlb <- adlb00 @@ -140,27 +110,27 @@ filtered_adlb <- adlb00 ## similar to LAB03: separate low and high and then combine ## esp as for 2 tests PARCAT5/6 is not the same for low/high direction -filtered_adlb_low <- filtered_adlb %>% - filter(!is.na(ATOXDSCL) & !is.na(ATOXGRL)) %>% +filtered_adlb_low <- filtered_adlb |> + filter(!is.na(ATOXDSCL) & !is.na(ATOXGRL)) |> mutate( ATOXDSCLH = ATOXDSCL, ATOXGRLH = ATOXGRL, BTOXGRLH = BTOXGRL, ATOXDIR = "LOW", - ANL045FL = ANL04FL - ) %>% + ANLHLFL = .data[[anl_low_fl]] + ) |> select(-c(ATOXGRL, ATOXGRH, ATOXDSCL, ATOXDSCH, BTOXGRL, BTOXGRH)) ### high grades: ATOXDSCH ATOXGRH ANL05FL -filtered_adlb_high <- filtered_adlb %>% - filter(!is.na(ATOXDSCH) & !is.na(ATOXGRH)) %>% +filtered_adlb_high <- filtered_adlb |> + filter(!is.na(ATOXDSCH) & !is.na(ATOXGRH)) |> mutate( ATOXDSCLH = ATOXDSCH, ATOXGRLH = ATOXGRH, BTOXGRLH = BTOXGRH, ATOXDIR = "HIGH", - ANL045FL = ANL05FL - ) %>% + ANLHLFL = .data[[anl_high_fl]] + ) |> select(-c(ATOXGRL, ATOXGRH, ATOXDSCL, ATOXDSCH, BTOXGRL, BTOXGRH)) @@ -169,43 +139,20 @@ filtered_adlb_tox <- bind_rows( filtered_adlb_low, filtered_adlb_high - ) %>% - select(-c(ATOXGR, ATOXGRN)) %>% + ) |> + select(-c(ATOXGR, ATOXGRN)) |> inner_join(adsl) - -### correction of proper category (PARCAT56) for HGB (LOW) and WBC (HIGH) -filtered_adlb_tox <- - filtered_adlb_tox %>% - mutate( - PARCAT56 = case_when( - PARAMCD == "HGB" & ATOXDIR == "LOW" ~ PARCAT6, - PARAMCD == "WBC" & ATOXDIR == "HIGH" ~ PARCAT6, - TRUE ~ PARCAT5 - ) - ) %>% - mutate( - PARCAT56 = factor( - PARCAT56, - levels = unique(c( - "Blood and lymphatic system disorders", - levels(adlb_complete$PARCAT5) - )) - ) - ) - - ### filter for timepoints (either per visit or worst over a time period (overall,period,phase,...)) - -## here: use worst overall: ANL04FL/ANL05FL --- ANL045FL +## here: use worst overall: ANL04FL/ANL05FL --- ANLHLFL ## if worst per period/phase:use ANL07/8 and ANL9/10 --- and ensure to create a combined version ANL078FL, ANL0910FL in the above code filtered_adlb_tox <- - filtered_adlb_tox %>% - filter(ANL045FL == "Y") + filtered_adlb_tox |> + filter(ANLHLFL == "Y") -## add the word Grade to ATOXGRLH,BTOXGRLH, For BTOXGRLH add an extra level (for display purpose) +## add the worst Grade to ATOXGRLH,BTOXGRLH, For BTOXGRLH add an extra level (for display purpose) filtered_adlb_tox <- - filtered_adlb_tox %>% + filtered_adlb_tox |> mutate( ATOXGRLH = factor(paste("Grade", ATOXGRLH), levels = paste("Grade", 0:4)), BTOXGRLH = factor( @@ -214,10 +161,30 @@ filtered_adlb_tox <- ) ) +# Filter to non-missing PARCAT4 only +filtered_adlb_tox <- filtered_adlb_tox |> + filter(PARCAT4 == "Graded tests") + +# Sort ATOXDSCLH alphabetically +### Sorting: alphabetically by base term, LOW before HIGH within same term +atoxdsclh_levels <- filtered_adlb_tox |> + distinct(ATOXDSCLH, ATOXDIR) |> + mutate( + base_term = sub(", (low|high)$", "", ATOXDSCLH, ignore.case = TRUE), + ATOXDIR_ord = factor(ATOXDIR, levels = c("LOW", "HIGH")) + ) |> + arrange(base_term, ATOXDIR_ord) |> + pull(ATOXDSCLH) |> + as.character() + + +filtered_adlb_tox <- filtered_adlb_tox |> + mutate(ATOXDSCLH = factor(as.character(ATOXDSCLH), levels = atoxdsclh_levels)) + ## trick for alt_counts_df to work with col splitting # add BNRIND to adsl, all assign to extra level N (column will be used for N counts) -adsl <- adsl %>% - mutate(BTOXGRLH = "N") %>% +adsl <- adsl |> + mutate(BTOXGRLH = "N") |> mutate(BTOXGRLH = factor(BTOXGRLH, levels = c("N", paste("Grade", 0:4)))) ## add variable for column split header @@ -228,35 +195,28 @@ filtered_adlb_tox$BTOXGRLH_header2 <- " " ## first column N should not appear un adsl$BTOXGRLH_header2 <- " " ## first column N should not appear under Baseline column span -### Alphabetical sorting of toxicity terms -atoxdsclh_levels <- sort(as.character(unique(filtered_adlb_tox$ATOXDSCLH))) - -filtered_adlb_tox <- filtered_adlb_tox %>% - mutate(ATOXDSCLH = factor(as.character(ATOXDSCLH), levels = atoxdsclh_levels)) - - check_categories <- unique( - filtered_adlb_tox %>% select(PARCAT3, PARCAT56, ATOXDSCLH) -) %>% - arrange(PARCAT3, PARCAT56, ATOXDSCLH) + filtered_adlb_tox |> select(PARCAT4, ATOXDSCLH) +) |> + arrange(PARCAT4, ATOXDSCLH) ################################################################################ # Define layout and build table: ################################################################################ -lyt <- basic_table(show_colcounts = FALSE) %>% +lyt <- basic_table(show_colcounts = FALSE) |> ## to ensure N column is not under the Baseline column span header - split_cols_by("BTOXGRLH_header2") %>% - split_cols_by("BTOXGRLH", split_fun = keep_split_levels("N")) %>% - split_cols_by("BTOXGRLH_header", nested = FALSE) %>% + split_cols_by("BTOXGRLH_header2") |> + split_cols_by("BTOXGRLH", split_fun = keep_split_levels("N")) |> + split_cols_by("BTOXGRLH_header", nested = FALSE) |> split_cols_by( "BTOXGRLH", split_fun = make_split_fun( pre = list(rm_levels(excl = "N")), post = list(add_overall_facet("TOTAL", "Total")) ) - ) %>% + ) |> #### replace split_rows and summarize by single analyze call ### a_freq_j only works due to ### special arguments can do the trick : denomf = adslx & .stats = count_unique @@ -271,18 +231,9 @@ lyt <- basic_table(show_colcounts = FALSE) %>% extrablankline = TRUE ), indent_mod = -1L - ) %>% + ) |> ## main part of table, restart row-split so nested = FALSE - split_rows_by( - "PARCAT56", - nested = FALSE, - label_pos = "topleft", - child_labels = "visible", - split_label = "NCI-CTCAE Category", - split_fun = drop_split_levels, - section_div = " " - ) %>% split_rows_by( "ATOXDSCLH", label_pos = "topleft", @@ -290,13 +241,13 @@ lyt <- basic_table(show_colcounts = FALSE) %>% split_label = "Laboratory Test", split_fun = drop_split_levels, section_div = " " - ) %>% + ) |> split_rows_by( trtvar, label_pos = "hidden", split_label = "Treatment Group", section_div = " " - ) %>% + ) |> ### a_freq_j ### the special statistic "n_rowdf" option does the trick here of getting the proper value for the N column summarize_row_groups( @@ -306,18 +257,18 @@ lyt <- basic_table(show_colcounts = FALSE) %>% .stats = "n_rowdf", restr_columns = c("N") ), - ) %>% + ) |> ## add extra level TOTAL using new_levels, rather than earlier technique ## advantage for denominator derivation -- n_rowdf can be used, if we'd like to present fraction as well ## switch .stats to count_unique_denom_fraction or count_unique_fraction analyze( "ATOXGRLH", - var_labels = "Worst toxicity grade, n", + var_labels = if (show_pct) "Worst toxicity grade, n (%)" else "Worst toxicity grade, n", show_labels = "visible", indent_mod = 1L, afun = a_freq_j, extra_args = list( - .stats = "count_unique", + .stats = if (show_pct) "count_unique_fraction" else "count_unique", denom = "n_rowdf", new_levels = list( c("Total"), @@ -331,22 +282,23 @@ lyt <- basic_table(show_colcounts = FALSE) %>% ) ) - if (nrow(filtered_adlb_tox) > 0) { - result <- build_table(lyt, filtered_adlb_tox, alt_counts_df = adsl) + result <- build_table(lyt, filtered_adlb_tox, alt_counts_df = adsl, round_type = "sas") } else { result <- NULL } ################################################################################ -# Set title +# Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) + +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(62, 7, 7, 5, 5, 5, 5, 7) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(54, 7, 7, 7, 7, 5, 5, 7) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, label_width_ins = 2.4, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab08.R b/tests/testthat/source_code/tsflab08.R new file mode 100644 index 00000000..d3e9ffb2 --- /dev/null +++ b/tests/testthat/source_code/tsflab08.R @@ -0,0 +1,211 @@ +library(envsetup) +library(tern) +library(dplyr) +library(tidyr) +library(lubridate) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFLAB08" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +# Population flag variable (default=SAFFL). +popfl <- "SAFFL" +# Actual treatment variable (default=TRT01A). +trtvar <- "TRT01A" + +ctrl_grp <- "Placebo" + +alt_ast <- "both" # Enzyme selection: "both", "alt", or "ast" + +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + + +################################################################################ +# Process Data: +################################################################################ + +enzyme_label <- switch(alt_ast, + alt = "ALT", + ast = "AST", + "ALT or AST" +) + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> + select(STUDYID, USUBJID, all_of(trtvar)) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +addili <- addili_jnj |> + filter( + .data[[popfl]] == "Y", + PARAMCD == "HDILI", + !is.na(.data[[trtvar]]) + ) |> + mutate( + AVALCAT = reorder(factor(paste0(AVALCAT1, " (", AVALCAT2, ")")), AVALCA1N) + ) |> + left_join(adsl |> select(USUBJID, colspan_trt), by = "USUBJID") + + +# Labels +quad_levels <- levels(addili$AVALCAT) +crit_levels <- c( + unique(as.character(na.omit(addili$AVALC[addili$AVALCA1N == 1]))), + unique(as.character(na.omit(addili$AVALC[addili$AVALCA1N == 2]))), + unique(as.character(na.omit(addili$AVALC[addili$AVALCA1N == 3]))), + unique(as.character(na.omit(addili$AVALC[addili$AVALCA1N == 4]))) +) + +hdili_label <- paste0(unique(as.character(na.omit(addili$CRIT1))), "~[super a]") +if (alt_ast != "both") { + crit_levels <- gsub("ALT or AST|ALT and AST", enzyme_label, crit_levels) + hdili_label <- gsub("ALT or AST", enzyme_label, hdili_label) +} + +################################################################################ +# Define layout and build table: +################################################################################ + +extra_args <- list( + denom = "n_parentdf", + denom_by = "PARAMCD", + .stats = "count_unique_fraction" +) + +lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> split_cols_by(trtvar) +} + +lyt <- lyt |> + append_topleft(c(" ", "Quadrant, n (%)")) |> + split_rows_by( + "PARAMCD", + split_fun = keep_split_levels("HDILI"), + nested = FALSE, + child_labels = "hidden" + ) |> + analyze( + "PARAMCD", + afun = a_freq_j, + extra_args = list( + val = "HDILI", + .stats = "count", + label = paste0( + "Subjects with on-treatment ", + enzyme_label, + " and TBILI values" + ), + extrablankline = TRUE + ), + show_labels = "hidden" + ) |> + split_rows_by( + "AVALCAT", + parent_name = "q1", + split_fun = keep_split_levels(quad_levels[1]), + nested = FALSE + ) |> + analyze( + "PARAMCD", + afun = a_freq_j, + extra_args = append( + extra_args, + list(val = "HDILI", label = crit_levels[1]) + ), + show_labels = "hidden" + ) |> + analyze( + "CRIT1FL", + afun = a_freq_j, + extra_args = append(extra_args, list(val = "Y", label = hdili_label)), + show_labels = "hidden", + indent_mod = 1L + ) |> + split_rows_by( + "AVALCAT", + parent_name = "q2-q4", + split_fun = keep_split_levels(quad_levels[2:4]), + nested = FALSE + ) |> + analyze( + "AVALC", + afun = a_freq_j, + extra_args = append(extra_args, list(drop_levels = TRUE)), + show_labels = "hidden" + ) + +result <- build_table( + lyt, + addili, + alt_counts_df = adsl, + round_type = "sas" +) + +################################################################################ +# Titles and Footnotes +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Output +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, label_width_ins = 2.4, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab09.R b/tests/testthat/source_code/tsflab09.R new file mode 100644 index 00000000..f33ba4b5 --- /dev/null +++ b/tests/testthat/source_code/tsflab09.R @@ -0,0 +1,199 @@ +library(envsetup) +library(tern) +library(dplyr) +library(tidyr) +library(lubridate) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSFLAB09" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +# Population flag variable (default=SAFFL). +popfl <- "SAFFL" +# Actual treatment variable (default=TRT01A). +trtvar <- "TRT01A" + +ctrl_grp <- "Placebo" + +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + + +################################################################################ +# Process Data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> + select(STUDYID, USUBJID, all_of(trtvar)) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +addili <- addili_jnj |> + filter( + .data[[popfl]] == "Y", + PARAMCD == "CDILI", + !is.na(.data[[trtvar]]) + ) |> + mutate( + AVALCAT = reorder(factor(paste0(AVALC, " (", AVALCAT2, ")")), AVALCA2N) + ) |> + left_join(adsl |> select(USUBJID, colspan_trt), by = "USUBJID") + + +# Labels +quad_levels <- levels(addili$AVALCAT) +cdili_label <- paste0(unique(as.character(na.omit(addili$CRIT1))), "~[super a]") + + +################################################################################ +# Define layout and build table: +################################################################################ + +extra_args <- list( + denom = "n_parentdf", + denom_by = "PARAMCD", + .stats = "count_unique_fraction" +) + +lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> split_cols_by(trtvar) +} + +lyt <- lyt |> + append_topleft(c(" ", "Quadrant, n (%)")) |> + split_rows_by( + "PARAMCD", + split_fun = keep_split_levels("CDILI"), + nested = FALSE, + child_labels = "hidden" + ) |> + analyze( + "PARAMCD", + afun = a_freq_j, + extra_args = list( + val = "CDILI", + .stats = "count", + label = "Subjects with on-treatment ALP and TBILI values", + extrablankline = TRUE + ), + show_labels = "hidden" + ) |> + split_rows_by( + "AVALCAT", + parent_name = "q1", + split_fun = keep_split_levels(quad_levels[1]), + nested = FALSE, + child_labels = "hidden" + ) |> + analyze( + "PARAMCD", + afun = a_freq_j, + extra_args = append( + extra_args, + list(val = "CDILI", label = quad_levels[1]) + ), + show_labels = "hidden" + ) |> + analyze( + "CRIT1FL", + afun = a_freq_j, + extra_args = append( + extra_args, + list( + val = "Y", + label = cdili_label + ) + ), + show_labels = "hidden", + indent_mod = 1L + ) |> + split_rows_by( + "AVALCAT", + parent_name = "q2-q4", + split_fun = keep_split_levels(quad_levels[2:4]), + nested = FALSE, + child_labels = "hidden" + ) |> + analyze( + "AVALCAT", + afun = a_freq_j, + extra_args = append(extra_args, list(drop_levels = TRUE)), + show_labels = "hidden" + ) + + +result <- build_table( + lyt, + addili, + alt_counts_df = adsl, + round_type = "sas" +) + + +################################################################################ +# Titles and Footnotes +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Output +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, label_width_ins = 2.4, orientation = "landscape") diff --git a/tests/testthat/source_code/tsflab10.R b/tests/testthat/source_code/tsflab10.R new file mode 100644 index 00000000..9c21178d --- /dev/null +++ b/tests/testthat/source_code/tsflab10.R @@ -0,0 +1,418 @@ +library(envsetup) +library(tern) +library(dplyr) +library(tidyr) +library(lubridate) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters +################################################################################ + +tblid <- "TSFLAB10" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +# Population flag variable (default=SAFFL). +popfl <- "SAFFL" +# Actual treatment variable (default=TRT01A). +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" +alt_ast <- "both" # Enzyme selection option: "both", "alt", or "ast" + +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +# Selected visits to subset the data. set to NULL to include all visits +selvisit <- c("Cycle 02", "Cycle 05", "Cycle 04", "Cycle 03") + +################################################################################ +# Process markedly abnormal values from spreadsheet: +################################################################################ + +### Markedly Abnormal spreadsheet +markedlyabnormal_file <- read_path(datapath, "markedlyabnormal.xlsx") + +markedlyabnormal_sheets <- readxl::excel_sheets(markedlyabnormal_file) + +lbmarkedlyabnormal_defs <- readxl::read_excel( + markedlyabnormal_file, + sheet = toupper("ADDILI") +) |> + filter(PARAMCD != "Parameter Code") |> + filter(grepl("CRIT", VARNAME)) |> + separate_rows(PARAMCD, sep = "\\s*\\|\\s*") + +CRITs <- lbmarkedlyabnormal_defs |> + filter(grepl("CRIT", VARNAME)) |> + pull(VARNAME) |> + unique() +################################################################################ +# Process Data +################################################################################ + +enzyme_label <- switch(alt_ast, + alt = "ALT", + ast = "AST", + "ALT or AST" +) + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> + select(STUDYID, USUBJID, all_of(trtvar)) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +addili <- addili_jnj |> + filter( + .data[[popfl]] == "Y", + !is.na(.data[[trtvar]]) + ) |> + filter(is.null(selvisit) | AVISIT %in% selvisit) |> + filter( + (alt_ast == "both" & PARCAT1 == "ALT or AST") | + (alt_ast == "alt" & PARAMCD == "ALT") | + (alt_ast == "ast" & PARAMCD == "AST") | + PARCAT1 == "TBILI" | + PARAMCD == "ALP" + ) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> + mutate( + PARCAT1 = case_when( + PARCAT1 %in% c("ALT or AST", "ALT", "AST") ~ enzyme_label, + TRUE ~ as.character(PARCAT1) + ), + DENOMFL = case_when( + PARCAT1 == enzyme_label & ONTRTFL == "Y" ~ "Y", + PARCAT1 == "TBILI" & ONTRTFL == "Y" ~ "Y", + PARCAT1 == "ALP" & ONTRTFL == "Y" ~ "Y", + TRUE ~ NA_character_ + ) + ) |> + left_join(adsl |> select(USUBJID, colspan_trt), by = "USUBJID") + +addili <- addili |> + mutate(across( + all_of(paste0(CRITs, "FL")), + ~ factor(., levels = c("Y", "N")) + )) |> + mutate(DENOMFL = factor(DENOMFL, levels = (c("Y", NA_character_)))) + + +xlabel_map <- lbmarkedlyabnormal_defs |> + left_join(addili |> select(PARAMCD, PARCAT1) |> distinct(), by = c("PARAMCD")) |> + filter(!is.na(PARCAT1)) |> + mutate( + var = paste0(VARNAME, "FL"), + label = CRIT, + value = "Y" + ) |> + mutate(CRIT_ = as.numeric(stringr::str_extract(label, "\\d+"))) |> + arrange(PARCAT1, PARAMCD, CRIT_, label, VARNAME) |> + select(PARCAT1, var, value, label) |> + distinct() + +xlabel_map1 <- xlabel_map |> + filter(PARCAT1 == enzyme_label) +xlabel_map2 <- xlabel_map |> + filter(PARCAT1 == "TBILI") +xlabel_map3 <- xlabel_map |> + filter(PARCAT1 == "ALP") + +################################################################################ +# Layout and Build +################################################################################ + +extra_args <- list( + denom = "n_df", + .stats = "count_unique_fraction", + na_str = "0" +) + +lyt <- basic_table(show_colcounts = TRUE) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> split_cols_by(trtvar) +} + +# enzyme section +lyt <- lyt |> + split_rows_by( + "PARCAT1", + parent_name = "enzyme", + split_fun = keep_split_levels(enzyme_label), + child_labels = "visible", + nested = FALSE, + ) |> + split_rows_by( + "DENOMFL", + label_pos = "topleft", + split_fun = drop_split_levels, + child_labels = "hidden", + split_label = " ", + section_div = " " + ) |> + summarize_row_groups( + "DENOMFL", + cfun = a_freq_j, + extra_args = list( + .stats = "n_df", + label = "Any on-treatment value", + riskdiff = FALSE + ) + ) |> + analyze( + xlabel_map1$var, + afun = a_freq_j, + extra_args = append( + extra_args, + list( + val = "Y", + label_map = xlabel_map1 + ) + ), + show_labels = "hidden" + ) |> + split_rows_by( + "PARCAT1", + parent_name = "pc_av_enzyme", + split_fun = keep_split_levels(enzyme_label), + child_labels = "hidden" + ) |> + split_rows_by( + "AVISIT", + parent_name = "av_enzyme", + split_fun = drop_split_levels, + indent_mod = 1L, + section_div = " " + ) |> + summarize_row_groups( + "AVISIT", + cfun = a_freq_j, + extra_args = list( + .stats = "n_df", + riskdiff = FALSE + ) + ) |> + analyze( + xlabel_map1$var, + afun = a_freq_j, + extra_args = append( + extra_args, + list( + val = "Y", + label_map = xlabel_map1 + ) + ), + show_labels = "hidden" + ) + +# TBILI section +lyt <- lyt |> + split_rows_by( + "PARCAT1", + parent_name = "enzyme", + split_fun = keep_split_levels("TBILI"), + child_labels = "visible", + nested = FALSE, + ) |> + split_rows_by( + "DENOMFL", + label_pos = "topleft", + split_fun = drop_split_levels, + child_labels = "hidden", + split_label = " ", + section_div = " " + ) |> + summarize_row_groups( + "DENOMFL", + cfun = a_freq_j, + extra_args = list( + .stats = "n_df", + label = "Any on-treatment value", + riskdiff = FALSE + ) + ) |> + analyze( + xlabel_map2$var, + afun = a_freq_j, + extra_args = append( + extra_args, + list( + val = "Y", + label_map = xlabel_map2 + ) + ), + show_labels = "hidden" + ) |> + split_rows_by( + "PARCAT1", + parent_name = "pc_av_enzyme", + split_fun = keep_split_levels("TBILI"), + child_labels = "hidden" + ) |> + split_rows_by( + "AVISIT", + parent_name = "av_enzyme", + split_fun = drop_split_levels, + indent_mod = 1L, + section_div = " " + ) |> + summarize_row_groups( + "AVISIT", + cfun = a_freq_j, + extra_args = list( + .stats = "n_df", + riskdiff = FALSE + ) + ) |> + analyze( + xlabel_map2$var, + afun = a_freq_j, + extra_args = append( + extra_args, + list( + val = "Y", + label_map = xlabel_map2 + ) + ), + show_labels = "hidden" + ) + +# ALP section +lyt <- lyt |> + split_rows_by( + "PARCAT1", + parent_name = "enzyme", + split_fun = keep_split_levels("ALP"), + child_labels = "visible", + nested = FALSE, + ) |> + split_rows_by( + "DENOMFL", + label_pos = "topleft", + split_fun = drop_split_levels, + child_labels = "hidden", + split_label = " ", + section_div = " " + ) |> + summarize_row_groups( + "DENOMFL", + cfun = a_freq_j, + extra_args = list( + .stats = "n_df", + label = "Any on-treatment value", + riskdiff = FALSE + ) + ) |> + analyze( + xlabel_map3$var, + afun = a_freq_j, + extra_args = append( + extra_args, + list( + val = "Y", + label_map = xlabel_map3 + ) + ), + show_labels = "hidden" + ) |> + split_rows_by( + "PARCAT1", + parent_name = "pc_av_enzyme", + split_fun = keep_split_levels("ALP"), + child_labels = "hidden" + ) |> + split_rows_by( + "AVISIT", + parent_name = "av_enzyme", + split_fun = drop_split_levels, + indent_mod = 1L, + section_div = " " + ) |> + summarize_row_groups( + "AVISIT", + cfun = a_freq_j, + extra_args = list( + .stats = "n_df", + riskdiff = FALSE + ) + ) |> + analyze( + xlabel_map3$var, + afun = a_freq_j, + extra_args = append( + extra_args, + list( + val = "Y", + label_map = xlabel_map3 + ) + ), + show_labels = "hidden" + ) + +result <- build_table(lyt, addili, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Titles and Footnotes +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Output +################################################################################ + +colwidth <- c(46, 17, 17, 17, 17) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, label_width_ins = 2.4, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfvit01.R b/tests/testthat/source_code/tsfvit01.R index 4612379b..1e3d8b8f 100644 --- a/tests/testthat/source_code/tsfvit01.R +++ b/tests/testthat/source_code/tsfvit01.R @@ -1,32 +1,8 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfvit01 -## R version: 4.2.1 -## Short Description: Program to create tsfvit01: Mean Change From Baseline -## in Blood Pressure Over Time -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, advs.RDS -## Output: tsfvit01.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) -library(tern) library(dplyr) library(rtables) library(junco) +library(haven) ################################################################################ # Define script level parameters: @@ -34,328 +10,405 @@ library(junco) tblid <- "TSFVIT01" fileid <- write_path(opath, tblid) -titles <- list( +tab_titles <- list( title = "Dummy Title", subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) +# Safety population flag (default=SAFFL). popfl <- "SAFFL" -trtvar <- "TRT01A" -ctrl_grp <- "Placebo" +# Actual treatment variable (default=TRT01A). +trtvar <- "TRT01A" +# Actual treatment levels (required to order the columns). +trtlev <- c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") -# Note on ancova parameter -# when ancova = TRUE -# ancova model will be used to calculate all mean/mean change columns -# not just those from the Difference column -# model specification -summ_vars <- list(arm = trtvar, covariates = NULL) +# Control arm name (one of the levels of the treatment variable). +ctrl_grp <- "Placebo" -# when ancova = FALSE, all mean/mean change columns will be from descriptive stats -# for the difference column descriptive stats will be based upon two-sample t-test -ancova <- FALSE +# Flag to enable comparison between treatment groups (e.g., mean difference vs. control). +comp_btw_group <- TRUE +# Add Active Study Agent Combined column? +combined_colspan_trt <- FALSE -comp_btw_group <- TRUE +# Vital sign parameters of interest. +paramcd <- c("SYSBP", "DIABP") -selparamcd <- c("DIABP", "SYSBP") -# to Update the timepoints to what is relevant for your study -# For the trial used for the shell program, the screening timepoint is the timepoint considered as baseline -# see further, an alternative method to identify all non-unscheduled visits based upon data -selvisit <- c("Screening", "Cycle 02", "Cycle 03", "Cycle 04") - -### as in dataset, order is important for later processing -### not automated, hard coded approach for ease of reading -### ideally the datasets already contain the appropriate case, to ensure units are in proper case -sel_param <- c( - "Systolic Blood Pressure (mmHg)", - "Diastolic Blood Pressure (mmHg)" -) -sel_param_case <- c( - "Systolic blood pressure (mmHg)", - "Diastolic blood pressure (mmHg)" -) +# Non-baseline visits of interest. +nonbl_visits <- c("Cycle 02", "Cycle 03", "Cycle 04") ################################################################################ -# Process Data: +# Process data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select( - STUDYID, - USUBJID, - all_of(c(popfl, trtvar)), - SEX, - AGEGR1, - RACE, - ETHNIC, - AGE +adsl <- adsl_jnj |> + select(USUBJID, all_of(c(popfl, trtvar))) |> + filter( + toupper(.data[[popfl]]) == "Y", + !is.na(.data[[trtvar]]) + ) |> + mutate( + !!trtvar := ordered(.data[[trtvar]], levels = trtlev), + ) |> + create_colspan_var( + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar ) -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -adsl$rrisk_header <- "Difference in Mean Change (95% CI)" -adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -advs00 <- advs_jnj %>% +advs <- advs_jnj |> select( USUBJID, + all_of(c(popfl, trtvar)), AVISITN, AVISIT, + ATPT, PARAMCD, PARAM, + PARAMN, AVAL, BASE, CHG, starts_with("ANL"), ABLFL, - APOBLFL, - VSSTAT - ) %>% - inner_join(adsl) - -# selection of all non-unscheduled visits from data -visits <- advs00 %>% - select(AVISIT) %>% - filter(!grepl("UNSCHEDULED", toupper(AVISIT))) - -visits$AVISIT <- droplevels(visits$AVISIT) -selvisit_data <- levels(visits$AVISIT) - -### if preferred to get it from data, rather than hardcoded list of visits -# selvisit <- selvisit_data - -## retrieve the precision of AVAL on the input dataset -## review outcome and make updates manually if needed -## the precision variable will be used for the parameter-based formats in layout - -## decimal = 4 is a cap in this derivation: if decimal precision of variable > decimal, the result will end up as decimal -## eg if AVAL has precision of 6 for parameter x, and decimal = 4, the resulting decimal value for parameter x is 4 + APOBLFL + ) |> + filter( + !is.na(USUBJID), + (.data[[popfl]] == "Y"), + !is.na(.data[[trtvar]]), + PARAMCD %in% paramcd + ) |> + mutate( + !!trtvar := ordered(.data[[trtvar]], levels = trtlev), + ABLFL := factor(ifelse(ABLFL == "Y" & !is.na(ABLFL), "Y", "N")), + APOBLFL := factor(ifelse(APOBLFL == "Y" & !is.na(APOBLFL), "Y", "N")), + PARAMCD = factor( + .data$PARAMCD, + levels = unique(.data[["PARAMCD"]])[order(unique(.data[["PARAMN"]]))] + ), + PARAM = factor( + .data$PARAM, + levels = unique(.data[["PARAM"]])[order(unique(.data[["PARAMN"]]))] + ), + AVISIT = factor( + ifelse(ABLFL == "Y" & !is.na(ABLFL), "Baseline", as.character(AVISIT)), + levels = unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))] + ) + ) -## note that precision is on the raw values, as we are presenting mean/ci, and extra digit will be added -## eg precision = 2 will result in mean/ci format xx.xxx (xx.xxx, xx.xxx) +# Reordered nonlbl_visits +nonbl_visits <- levels(advs$AVISIT)[levels(advs$AVISIT) %in% nonbl_visits] -vs_precision <- tidytlg:::make_precision_data( - df = advs00, - decimal = 3, - precisionby = "PARAMCD", - precisionon = "AVAL" -) +advs <- inner_join(adsl, advs, by = c("USUBJID", popfl, trtvar)) -### data preparation +# Safety checks on the data. -filtered_advs <- advs00 %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) - -#### perform check on unique record per subject/param/timepoint -check_unique <- filtered_advs %>% - group_by(USUBJID, PARAMCD, AVISIT) %>% - mutate(n_recsub = n()) %>% +advs_checks_unique <- advs |> + filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) |> + group_by(USUBJID, PARAMCD, AVISIT) |> + mutate(n_recsub = n()) |> filter(n_recsub > 1) -if (nrow(check_unique) > 0) { - stop( +if (nrow(advs_checks_unique) > 0) { + message( "Your input dataset needs extra attention, as some subjects have more than one record per parameter/visit" ) - ### you will run into issues with fraction portion in count_denom_fraction, as count > denom, and fraction > 1 if you don't adjust your input dataset - - # Possible extra derivation - just to ensure program can run without issues - ### Study team is responsible for adding this derivation onto ADaM dataset and ensure proper derivation rule for ANL02FL is implemented !!!!!!!!!! - filtered_advsx <- advs00 %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) %>% - group_by(USUBJID, PARAM, AVISIT) %>% - mutate(n_sub = n()) %>% - arrange(USUBJID, PARAM, AVISIT, ADT) %>% - mutate(i = vctrs::vec_group_id(ADT)) %>% - mutate( - ANL02FL = case_when( - n_sub == 1 ~ "Y", - i == 1 ~ "Y" - ) - ) %>% - select(-c(i, n_sub)) %>% - ungroup() - - filtered_advs <- filtered_advsx %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) - - ## now your data should contain 1 record per subject per parameter } -### for denominator per timepoint: all records from advs on this timepoint: ignoring anl01fl/anl02fl/param -filtered_advs_timepoints <- unique( - advs00 %>% - filter(AVISIT %in% selvisit) %>% - select(USUBJID, AVISITN, AVISIT) -) %>% - inner_join(adsl) - -filtered_advs$PARAM <- factor( - as.character(filtered_advs$PARAM), - levels = sel_param, - labels = sel_param_case -) - -params <- unique(filtered_advs %>% select(PARAMCD, PARAM)) - -filtered_advs_timepoints <- filtered_advs_timepoints %>% - mutate(dummy_join = 1) %>% - full_join( - params %>% mutate(dummy_join = 1), - relationship = "many-to-many" - ) %>% - select(-dummy_join) - -### identify subjects in filtered_advs_timepoints and not in filtered_advs +advs_checked <- advs |> + filter( + toupper(.data[[popfl]]) == "Y", + toupper(ANL01FL) == "Y", + toupper(ANL02FL) == "Y" + ) |> + mutate( + flag = if_else(is.na(AVAL), 1L, 0L), + flag1 = if_else(toupper(APOBLFL) == "Y" & is.na(BASE), 1L, 0L) + ) -extra_sub <- anti_join(filtered_advs_timepoints, filtered_advs) +if (nrow(filter(advs_checked, flag == 1)) > 0) { + message("Pay attention: There are tests with missing AVAL: ") +} -### only add these extra_sub to -### this will ensure we still meet the one record per subject per timepoint -### this will ensure length(x) can be used for the denominator derivation inside summarize_aval_chg_diff function +if (nrow(filter(advs_checked, flag1 == 1)) > 0) { + message("Pay attention: There are postbaseline tests without baseline: ") +} -filtered_advs <- bind_rows(filtered_advs, extra_sub) %>% - arrange(USUBJID, PARAM, AVISITN) +# Keep only records with non-missing AVAL +advs <- filter(advs, !is.na(AVAL)) + +# varying decimal precision ---- +# manual setup example +prec <- dplyr::tibble(PARAMCD = unique(advs$PARAMCD), d = 1) +prec$d[prec$PARAMCD %in% c("DIABP")] <- 2 + +# alternative: use tidytlg make_precision function +# DTYPE='AVERAGE' records are excluded from decimal precision +# advs_avg <- advs |> filter(!DTYPE=="AVERAGE") + +# prec2 <- tidytlg:::make_precision_data( +# df = advs_avg, +# decimal = 4, +# precisionby = "PARAMCD", +# precisionon = "AVAL" +# ) |> +# rename(c(d = "decimal")) + +.stats_all <- c("n", "mean_sd", "median_range", "diff_means_est_ci") +# add d-based formats for all required stats onto precision dataset +prec <- fmt_spec_df_d( + prec, + d_column = "d", + fmt_column = "fmt_d", + stats_in = .stats_all, + fmt_d_def = junco_def_d_all, + fmt_d_in = NULL +) -filtered_advs <- filtered_advs %>% - inner_join(vs_precision, by = "PARAMCD") +# review d-based formats +fmt_d_details <- lapply(prec$PARAMCD, FUN = function(x) { + fmt <- prec[prec$PARAMCD == x, ][["fmt_d"]][[1]] + get_fmt_details( + fmt, + as_tibble = TRUE + ) +}) +names(fmt_d_details) <- prec$PARAMCD +# fmt_d_details -### important: previous actions lost the label of variables -### in order to be able to use obj_label(filtered_advs$PARAM) in layout, need to redefine the label -filtered_advs <- var_relabel_list(filtered_advs, var_labels(advs00, fill = T)) +# add precision specific format to advs input dataset +advs <- advs |> + left_join(prec) ################################################################################ # Define layout and build table: ################################################################################ -summ_vars <- list(arm = trtvar, covariates = NULL) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) -multivars <- c("AVAL", "AVAL", "CHG") - -extra_args_3col <- list( - format_na_str = rep("NA", 3), - d = "decimal", - variables = summ_vars, - ref_path = ref_path, - ancova = ancova, - comp_btw_group = comp_btw_group, - multivars = multivars +colspan_trt_map <- if (!is.null(ctrl_grp)) { + create_colspan_map( + advs, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) +} else { + tibble( + colspan_trt = "Active Study Agent", + !!trtvar := levels(advs[[trtvar]]) + ) +} + +split_combined <- if (combined_colspan_trt) { + # Set up levels and label for the required combined columns. + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = setdiff(levels(advs[[trtvar]]), ctrl_grp) + ) + + # Choose if any facets need to be removed, + # e.g remove the combined column for placebo. + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} else { + NULL +} + +# Common stats for time point / change from baseline to time point. +stats <- c("n", "mean_sd", "median_range") +formats <- junco_get_formats_from_stats(stats) +labels <- junco_get_labels_from_stats(stats, labels_in = c(n = "N")) +indent_mods <- c(n = 1L, mean_sd = 2L, median_range = 2L) + +# Dynamic label for the "Change from baseline ..." sections. +a_chg_label <- function(x, .spl_context) { + last_split <- length(.spl_context$split) + label <- paste("Change from baseline to", .spl_context$value[last_split]) + rtables::rcell(NULL, label = label) +} + +# Difference in means parameters. +CI_cl <- tern::control_analyze_vars()$conf_level +a_diff_means_args <- list( + ref_path = c("colspan_trt", " ", trtvar, ctrl_grp), + conf.level = CI_cl, + .stats = "diff_means_est_ci", + .formats = "default", + .labels = c( + diff_means_est_ci = paste0( + "Difference in mean vs. ", + tolower(ctrl_grp), + " (", + tern::f_conf_level(CI_cl), + ")" + ) + ) ) -lyt <- basic_table(show_colcounts = FALSE, colcount_format = "N=xx") %>% - ### first columns +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx", + top_level_section_div = " " +) |> + append_topleft("Parameter") |> split_cols_by( "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map), - show_colcounts = FALSE - ) %>% - split_cols_by(trtvar, show_colcounts = TRUE, colcount_format = "N=xx") %>% + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) |> + split_cols_by(trtvar, split_fun = split_combined) |> split_rows_by( - "PARAM", - label_pos = "topleft", - split_label = "Blood Pressure", - section_div = " ", - split_fun = drop_split_levels - ) %>% - ## note the child_labels = hidden for AVISIT, these labels will be taken care off by - ## applying function summarize_aval_chg_diff further in the layout + "PARAMCD", + split_fun = keep_split_levels(paramcd), + labels_var = "PARAM", + child_labels = "visible" + ) |> + summarize_row_groups( + "AVAL", + cfun = c_summary_subset_label, + extra_args = list( + filter_expr = expression(ABLFL == "Y"), + .stats = stats, + .formats = "default", + formats_var = "fmt_d", + .labels = labels, + .indent_mods = indent_mods, + label = "Baseline" + ) + ) |> split_rows_by( "AVISIT", - label_pos = "topleft", - split_label = "Study Visit", - split_fun = drop_split_levels, - child_labels = "hidden" - ) %>% - ## set up a 3 column split - split_cols_by_multivar( - multivars, - varlabels = c( - "n/N (%)", - "Mean (95% CI)", - "Mean Change From Baseline (95% CI)" - ) - ) %>% - ### restart for the rrisk_header columns - note the nested = FALSE option - ### also note the child_labels = "hidden" in both PARAM and AVISIT - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - split_fun = remove_split_levels(ctrl_grp), - labels_var = "rrisk_label", - show_colcounts = TRUE, - colcount_format = "N=xx" - ) %>% - ### difference columns : just 1 column & analysis needs to be done on change - split_cols_by_multivar(multivars[3], varlabels = c(" ")) %>% - ### the variable passed here in analyze is not used (STUDYID), it is a dummy var passing, - ### the function summarize_aval_chg_diff grabs the required vars from cols_by_multivar calls + split_fun = keep_split_levels(nonbl_visits), + indent_mod = -1, + section_div = " ", + ) |> + analyze( + "AVAL", + afun = tern::a_summary, + extra_args = list( + .stats = stats, + .formats = "default", + .labels = labels, + .indent_mods = indent_mods - 1, + na_rm = TRUE + ), + formats_var = "fmt_d", + show_labels = "hidden", + section_div = " " + ) |> + analyze( + "CHG", + afun = a_chg_label, + table_names = "chg_bl_label", + show_labels = "hidden", + indent_mod = -1L + ) |> + analyze( + "CHG", + afun = tern::a_summary, + extra_args = list( + .stats = "n", + .formats = "default", + .labels = labels, + na_rm = TRUE # Subjects with non-missing values at both baseline and the postbaseline time point. + ), + formats_var = "fmt_d", + show_labels = "hidden" + ) |> + analyze( + "BASE", + afun = a_summary_subset, + extra_args = list( + filter_expr = expression(!is.na(CHG)), + na_rm = TRUE, + .stats = "mean_sd", + .formats = "default", + .labels = c(mean_sd = "Baseline mean (SD)") + ), + formats_var = "fmt_d", + table_names = "chg_bl_mean", + show_labels = "hidden", + indent_mod = 1L + ) |> analyze( - "STUDYID", - afun = a_summarize_aval_chg_diff_j, - extra_args = extra_args_3col + "CHG", + afun = tern::a_summary, + extra_args = list( + .stats = c("mean_sd", "median_range"), + .formats = "default", + .labels = labels, + na_rm = TRUE + ), + formats_var = "fmt_d", + table_names = "chg_mm", + show_labels = "hidden", + indent_mod = 1L ) -result <- build_table(lyt, filtered_advs, alt_counts_df = adsl) +if (comp_btw_group) { + lyt <- lyt |> + analyze( + "CHG", + afun = a_diff_means, + extra_args = a_diff_means_args, + formats_var = "fmt_d", + table_names = "chg_diff_means", + show_labels = "hidden", + indent_mod = 1L + ) +} + +result <- build_table(lyt, advs, alt_counts_df = adsl, round_type = "sas") + +# Add an empty line after each "Screening" section. +# Use `section_div_at_path()` as a workaround for the missing +# `section_div` argument in `summarize_row_groups()`. +# (Feature request: https://github.com/insightsengineering/rtables/issues/1083) +# The path below is determined from `rtables::row_paths_summary(result)`. +section_div_at_path(result, c("PARAMCD", "*", "@content", last(stats))) <- " " ################################################################################ # Post-Processing: -# - Remove the N=xx column headers for the difference vs PBO columns +# - Adjust Combined (if displayed) columns Ns (When sequence of +# treatments is used, one subject receives more than on treatment. Hence, +# there are many rows for one unique subjects, while N should represent only +# unique subjects). ################################################################################ -remove_col_count2 <- function(result, string = paste("vs", ctrl_grp)) { - mcdf <- make_col_df(result, visible_only = FALSE) - mcdfsel <- mcdf %>% - filter(stringr::str_detect(toupper(label), toupper(string))) %>% - pull(path) - - for (i in seq_along(mcdfsel)) { - facet_colcount(result, mcdfsel[[i]]) <- NA +if (combined_colspan_trt) { + adsl_no_ctrl <- if (is.null(ctrl_grp)) { + adaper + } else { + adsl[adsl[[trtvar]] != ctrl_grp, ] } - - return(result) + n_combined <- length(unique(adsl_no_ctrl$USUBJID)) + colpath_combined <- c("colspan_trt", "Active Study Agent", trtvar, "Combined") + facet_colcount(result, colpath_combined) <- n_combined } -result <- remove_col_count2(result) - ################################################################################ # Add titles and footnotes: ################################################################################ -result <- set_titles(result, titles) +result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table: ################################################################################ -colwidth <- c(54, 29, 54, 51, 29, 54, 47, 29, 54, 49, 51, 44) -tt_to_tlgrtf( - colwidths = colwidth, - result, - file = fileid, - nosplitin = list(cols = c(trtvar, "rrisk_header")), - orientation = "landscape" -) +colwidth <- c(64, 41, 41, 41) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfvit01a.R b/tests/testthat/source_code/tsfvit01a.R deleted file mode 100644 index 645a50f1..00000000 --- a/tests/testthat/source_code/tsfvit01a.R +++ /dev/null @@ -1,440 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfvit01a -## R version: 4.2.1 -## Short Description: Program to create tsfvit01a: Mean Change From Baseline -## in Blood Pressure Over Time by [Subgroup] -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, advs.RDS -## Output: tsfvit01a.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFVIT01a" -fileid <- write_path(opath, tblid) -titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -popfl <- "SAFFL" -trtvar <- "TRT01A" -ctrl_grp <- "Placebo" -subgrpvar <- "AGEGR1" -subgrplbl <- "Age: %s years" - -page_by <- FALSE # Set page_by TRUE/FALSE if you (do not) wish to start a new page after a new subgroup -indent_adj <- 0L -if (page_by) { - indent_adj <- 0L -} - - -# Note on ancova parameter -# when ancova = TRUE -# ancova model will be used to calculate all mean/mean change columns -# not just those from the Difference column -# model specification -summ_vars <- list(arm = trtvar, covariates = NULL) - -# when ancova = FALSE, all mean/mean change columns will be from descriptive stats -# for the difference column descriptive stats will be based upon two-sample t-test -ancova <- FALSE - - -comp_btw_group <- TRUE - - -selparamcd <- c("DIABP", "SYSBP") -# to Update the timepoints to what is relevant for your study -# For the trial used for the shell program, the screening timepoint is the timepoint considered as baseline -# see further, an alternative method to identify all non-unscheduled visits based upon data -selvisit <- c("Screening", "Cycle 02", "Cycle 03", "Cycle 04") - -### as in dataset, order is important for later processing -### not automated, hard coded approach for ease of reading -### ideally the datasets already contain the appropriate case, to ensure units are in proper case -sel_param <- c( - "Systolic Blood Pressure (mmHg)", - "Diastolic Blood Pressure (mmHg)" -) -sel_param_case <- c( - "Systolic blood pressure (mmHg)", - "Diastolic blood pressure (mmHg)" -) - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select( - STUDYID, - USUBJID, - all_of(c(popfl, trtvar, subgrpvar)), - SEX, - AGEGR1, - RACE, - ETHNIC, - AGE - ) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -adsl$rrisk_header <- "Difference in Mean Change (95% CI)" -adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - -advs00 <- advs_jnj %>% - select( - USUBJID, - AVISITN, - AVISIT, - PARAMCD, - PARAM, - AVAL, - BASE, - CHG, - starts_with("ANL"), - ABLFL, - APOBLFL, - VSSTAT - ) %>% - mutate(invsdata = "Y") %>% - inner_join(adsl) - -# selection of all non-unscheduled visits from data -visits <- advs00 %>% - select(AVISIT) %>% - filter(!grepl("UNSCHEDULED", toupper(AVISIT))) - -visits$AVISIT <- droplevels(visits$AVISIT) -selvisit_data <- levels(visits$AVISIT) - -### if preferred to get it from data, rather than hardcoded list of visits -# selvisit <- selvisit_data - -## retrieve the precision of AVAL on the input dataset -## review outcome and make updates manually if needed -## the precision variable will be used for the parameter-based formats in layout - -## decimal = 4 is a cap in this derivation: if decimal precision of variable > decimal, the result will end up as decimal -## eg if AVAL has precision of 6 for parameter x, and decimal = 4, the resulting decimal value for parameter x is 4 - -## note that precision is on the raw values, as we are presenting mean/ci, and extra digit will be added -## eg precision = 2 will result in mean/ci format xx.xxx (xx.xxx, xx.xxx) - -vs_precision <- tidytlg:::make_precision_data( - df = advs00, - decimal = 4, - precisionby = "PARAMCD", - precisionon = "AVAL" -) - -### data preparation - -filtered_advs_00 <- advs00 %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) - -#### perform check on unique record per subject/param/timepoint -check_unique <- filtered_advs_00 %>% - group_by(USUBJID, PARAMCD, AVISIT) %>% - mutate(n_recsub = n()) %>% - filter(n_recsub > 1) - -if (nrow(check_unique) > 0) { - stop( - "Your input dataset needs extra attention, as some subjects have more than one record per parameter/visit" - ) - ### you will run into issues with fraction portion in count_denom_fraction, as count > denom, and fraction > 1 if you don't adjust your input dataset - - # Possible extra derivation - just to ensure program can run without issues - ### Study team is responsible for adding this derivation onto ADaM dataset and ensure proper derivation rule for ANL02FL is implemented !!!!!!!!!! - filtered_advs_00x <- advs00 %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) %>% - group_by(USUBJID, PARAM, AVISIT) %>% - mutate(n_sub = n()) %>% - arrange(USUBJID, PARAM, AVISIT, ADT) %>% - mutate(i = vctrs::vec_group_id(ADT)) %>% - mutate( - ANL02FL = case_when( - n_sub == 1 ~ "Y", - i == 1 ~ "Y" - ) - ) %>% - select(-c(i, n_sub)) %>% - ungroup() - - filtered_advs_00 <- filtered_advs_00x %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - ### unique record per timepoint: - filter(ANL02FL == "Y" & (ABLFL == "Y" | APOBLFL == "Y")) - - ## now your data should contain 1 record per subject per parameter -} - -### for denominator per timepoint: all records from advs on this timepoint: ignoring anl01fl/anl02fl/param -filtered_advs_timepoints <- unique( - advs00 %>% - filter(AVISIT %in% selvisit) %>% - select(USUBJID, AVISITN, AVISIT, invsdata) -) %>% - inner_join(adsl) - -params <- unique(filtered_advs_00 %>% select(PARAMCD, PARAM)) - -filtered_advs_timepoints <- filtered_advs_timepoints %>% - mutate(dummy_join = 1) %>% - full_join( - params %>% mutate(dummy_join = 1), - relationship = "many-to-many" - ) %>% - select(-dummy_join) - -### identify subjects in filtered_advs_timepoints and not in filtered_advs - -extra_sub <- anti_join(filtered_advs_timepoints, filtered_advs_00) %>% - mutate(extra_sub = "Y") - -attr(extra_sub$extra_sub, "label") <- "Extra Subject step 1" - -### add these extra_sub dataframes to -### this will ensure we still meet the one record per subject per timepoint -### note that we can no longer use length(x) can be used for the denominator derivation inside summarize_aval_chg_diff function -filtered_advs <- bind_rows(filtered_advs_00, extra_sub) %>% - arrange(USUBJID, PARAM, AVISITN) - -filtered_advs <- filtered_advs %>% - inner_join(vs_precision, by = "PARAMCD") - -#### Only In case we want the subgroup N to come from ADSL, and not just from ADVS - -### also add adsl subjects that have no vs data --- for subgroup counts from adsl - -advs_timepoints_subgroups <- - adsl %>% - select(USUBJID) %>% - # define factor PARAMCD/AVISIT with one category, all levels we need - mutate( - PARAMCD = factor(selparamcd[1], levels = selparamcd), - AVISIT = factor(selvisit[1], levels = selvisit) - ) %>% - # expand dataset to show all levels - tidyr::complete(., USUBJID, PARAMCD, AVISIT) - -extra_sub2 <- - anti_join( - advs_timepoints_subgroups, - filtered_advs_00 %>% select(USUBJID, AVISITN, AVISIT, PARAMCD, PARAM) - ) %>% - left_join(., unique(advs00 %>% select(AVISITN, AVISIT, PARAMCD, PARAM))) %>% - anti_join(., extra_sub) %>% - inner_join(adsl) %>% - mutate(extra_sub2 = "Y") - -attr(extra_sub2$extra_sub2, "label") <- "Extra Subject step 2" - -### add these extra_sub dataframe as well -### this will ensure we still meet the one record per subject per timepoint -### However, by adding also subjects without data in vs, we can no longer use length(x) for the denominator derivation inside summarize_aval_chg_diff function -filtered_advs <- bind_rows(filtered_advs, extra_sub2) %>% - arrange(USUBJID, PARAM, AVISITN) - -### important: previous actions lost the label of variables - -## do these 2 manually, as these are not available on advs00 -attr(filtered_advs$extra_sub, "label") <- "Extra Subject step 1" -attr(filtered_advs$extra_sub2, "label") <- "Extra Subject step 2" - -### important: previous actions lost the label of variables -### in order to be able to use obj_label(filtered_advs$PARAM) in layout, need to redefine the label -filtered_advs <- var_relabel_list(filtered_advs, var_labels(advs00, fill = T)) - - -filtered_advs$PARAM <- factor( - as.character(filtered_advs$PARAM), - levels = sel_param, - labels = sel_param_case -) - - -#### Note : variable invsdata will be used to differentiate records from subjects in vsdata at timepoint and subjects not in vsdata (only in adsl) -#### is.na(filtered_advs$invsdata) corresponds to filtered_advs$extra_sub2 == "Y" - -## check1 <- filtered_advs %>% filter(extra_sub2 == "Y") %>% select(USUBJID,invsdata,extra_sub2,PARAMCD,AVISIT,AVAL) -## check2 <- filtered_advs %>% filter(is.na(invsdata)) %>% select(USUBJID,invsdata,extra_sub2,PARAMCD,AVISIT,AVAL) - -################################################################################ -# Define layout and build table: -################################################################################ - -multivars <- c("AVAL", "AVAL", "CHG") - -extra_args_3col <- list( - format_na_str = rep("NA", 3), - d = "decimal", - variables = summ_vars, - ref_path = ref_path, - ancova = ancova, - comp_btw_group = comp_btw_group, - multivars = multivars, - indatavar = "invsdata" -) - -lyt <- basic_table(show_colcounts = FALSE, colcount_format = "N=xx") %>% - ### first columns - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar, show_colcounts = TRUE, colcount_format = "N=xx") %>% - split_rows_by( - subgrpvar, - label_pos = "hidden", - section_div = " ", - split_fun = drop_split_levels, - page_by = page_by - ) %>% - ### just show number of subjects in current level of subgrpvar - ### only show this number in the first AVAL column - summarize_row_groups( - var = subgrpvar, - cfun = a_freq_j, - extra_args = list( - label_fstr = subgrplbl, - extrablankline = TRUE, - restr_columns = "AVAL", - .stats = c("n_altdf"), - riskdiff = FALSE, - denom_by = subgrpvar - ) - ) %>% - split_rows_by( - "PARAM", - label_pos = "topleft", - split_label = "Blood Pressure", - section_div = " ", - split_fun = drop_split_levels - ) %>% - ## note the child_labels = hidden for AVISIT, these labels will be taken care off by - ## applying function summarize_aval_chg_diff further in the layout - split_rows_by( - "AVISIT", - label_pos = "topleft", - split_label = "Study Visit", - split_fun = drop_split_levels, - child_labels = "hidden" - ) %>% - ## set up a 3 column split - split_cols_by_multivar( - multivars, - varlabels = c( - "n/N (%)", - "Mean (95% CI)", - "Mean Change From Baseline (95% CI)" - ) - ) %>% - ### restart for the rrisk_header columns - note the nested = FALSE option - ### also note the child_labels = "hidden" in both PARAM and AVISIT - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - split_fun = remove_split_levels(ctrl_grp), - labels_var = "rrisk_label", - show_colcounts = TRUE, - colcount_format = "N=xx" - ) %>% - ### difference columns : just 1 column & analysis needs to be done on change - split_cols_by_multivar(c("CHG"), varlabels = c(" ")) %>% - ### the variable passed here in analyze is not used (STUDYID), it is a dummy var passing, - ### the function summarize_aval_chg_diff grabs the required vars from cols_by_multivar calls - analyze( - "STUDYID", - afun = a_summarize_aval_chg_diff_j, - extra_args = extra_args_3col - ) - -result <- build_table(lyt, filtered_advs, alt_counts_df = adsl) - - -################################################################################ -# Post-Processing: -# - Remove the N=xx column headers for the difference vs PBO columns -################################################################################ -remove_col_count2 <- function(result, string = paste("vs", ctrl_grp)) { - mcdf <- make_col_df(result, visible_only = FALSE) - mcdfsel <- mcdf %>% - filter(stringr::str_detect(toupper(label), toupper(string))) %>% - pull(path) - - for (i in seq_along(mcdfsel)) { - facet_colcount(result, mcdfsel[[i]]) <- NA - } - - return(result) -} - -result <- remove_col_count2(result) - -############################################################################### -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(56, 29, 60, 59, 29, 60, 57, 29, 60, 57, 57, 57) - -tt_to_tlgrtf( - colwidths = colwidth, - result, - file = fileid, - nosplitin = list(cols = c(trtvar, "rrisk_header")), - orientation = "landscape" -) diff --git a/tests/testthat/source_code/tsfvit02.R b/tests/testthat/source_code/tsfvit02.R index b398a66e..197b6d13 100644 --- a/tests/testthat/source_code/tsfvit02.R +++ b/tests/testthat/source_code/tsfvit02.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfvit02 -## R version: 4.2.1 -## Short Description: Program to create tsfvit02: Subjects With Maximum -## On-treatment Systolic Blood Pressure by Category of Blood Pressure -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, advs.RDS -## Output: tsfvit02.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -46,31 +22,53 @@ ctrl_grp <- "Placebo" selparamcd <- c("SYSBP", "DIABP") -### tsfvit02a -selparamcd <- c("SYSBP") - -### tsfvit02b : no code updates needed -# selparamcd <- c("DIABP") +### criteria flags to consider for output +crit_flags <- paste0("CRIT", 1:6, "FL") ### as in dataset, order is important for later processing ### not automated, hard coded approach for ease of reading ### ideally the datasets already contain the appropriate case, to ensure units are in proper case -sel_param <- c("Systolic Blood Pressure (mmHg)") -sel_param_case <- c("Systolic blood pressure (mmHg)") +sel_param <- c("Systolic Blood Pressure (mmHg)", "Diastolic Blood Pressure (mmHg)") + +### Parameter headers label +sel_param_case <- c("Maximum systolic blood pressure (mmHg)", "Maximum diastolic blood pressure (mmHg)") + +relrisk <- TRUE +# by default JJCS there is no need to add relative risk columns + +combined_colspan_trt <- FALSE + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} ################################################################################ # Process Data: ################################################################################ - -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> select( USUBJID, all_of(c(popfl, trtvar)), - SEX_DECODE, + SEX, AGEGR1, - RACE_DECODE, - ETHNIC_DECODE + RACE, + ETHNIC ) adsl$colspan_trt <- factor( @@ -90,23 +88,10 @@ colspan_trt_map <- create_colspan_map( trt_var = trtvar ) -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) -### note: by filter ANL06FL, this table is restricted to On-treatment values, per definition of ANL06FL -### therefor, no need to add ONTRTFL in filter -### if derivation of ANL06FL is not restricted to ONTRTFL records, adding ONTRTFL here will not give the correct answer either -### as mixing worst with other period is not giving the proper selection !!! -filtered_advs <- advs_jnj %>% - filter(PARAMCD %in% selparamcd) %>% - filter(ANL06FL == "Y") %>% +advs00 <- advs_jnj |> + filter(PARAMCD %in% selparamcd) |> select( STUDYID, USUBJID, @@ -115,128 +100,280 @@ filtered_advs <- advs_jnj %>% AVALCAT1, AVALCA1N, AVISIT, + ANL03FL, ANL06FL, APOBLFL, - ONTRTFL - ) %>% - inner_join(adsl) + starts_with("CRIT") + ) |> + inner_join(adsl) |> + # Factor the data columns to ensure they sort correctly in the output + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) +### note: by filter ANL03FL, this table is restricted to maximum On-treatment values, per definition of ANL03FL +filtered_advs <- advs00 |> + filter(ANL03FL == "Y") + +# Factor the data columns to ensure they sort correctly in the output filtered_advs$PARAM <- factor( - as.character(filtered_advs$PARAM), - levels = sel_param, - labels = sel_param_case + filtered_advs$PARAM, + levels = c(as.character(sel_param)), + labels = c(as.character(sel_param_case)) ) +### Systolic parameter +filtered_advs1 <- filtered_advs |> + filter(PARAM == sel_param_case[1]) -################################################################################ -# Process markedly abnormal values from spreadsheet: -################################################################################ +### Systolic parameter +filtered_advs2 <- filtered_advs |> + filter(PARAM == sel_param_case[2]) -### Markedly Abnormal spreadsheet - -markedlyabnormal_file <- file.path(datapath, "markedlyabnormal.xlsx") - - - - -lbmarkedlyabnormal_defs <- readxl::read_excel( - markedlyabnormal_file, - sheet = "ADVS" -) %>% - filter(PARAMCD != "Parameter Code") %>% - arrange(PARAMCD, VARNAME, ORDER) %>% - filter(VARNAME == "AVALCAT1") %>% - filter(PARAMCD %in% selparamcd) %>% - left_join(., unique(filtered_advs %>% select(PARAMCD, PARAM))) - - -# code_decode <- getcodelistinfo(df=filtered_advs, -# domain="advs", -# vars = c("AVALCAT1"), -# APT= apt, -# adam_meta_loc=am_in, -# sdtm_meta_loc=dm_in) -# -# -# code_decode <- code_decode %>% -# filter(PARAMCD %in% selparamcd) %>% -# left_join(.,unique(filtered_advs %>% select(PARAMCD,PARAM))) - -### create a mapping table for usage in split_fun trim_levels_to_map, -### to ensure only the levels appropriate for the selected parameters are covered - -param_map <- lbmarkedlyabnormal_defs %>% - rename(AVALCAT1 = CRIT) %>% - ### no factors are allowed in this split_fun map definition - mutate(PARAM = as.character(PARAM)) %>% - select(PARAM, AVALCAT1) - -# if no code list was defined, not all defined categories might be present on data -# sas2rds conversion might not have added all categories as factor levels - need to do this here -if ( - class(filtered_advs$AVALCAT1) == "character" || - !all(unique(param_map$AVALCAT1) %in% levels(filtered_advs$AVALCAT1)) -) { - filtered_advs$AVALCAT1 <- factor( - as.character(filtered_advs$AVALCAT1), - levels = unique(param_map$AVALCAT1) +### note: by filter ANL06FL, this table is restricted to On-treatment values, per definition of ANL06FL +filtered_advs3 <- advs00 |> + filter(ANL06FL == "Y") |> + mutate( + CRIT1FL_SYS = case_when( + PARAMCD == "SYSBP" ~ CRIT1FL + ), + CRIT1FL_DIA = case_when( + PARAMCD == "DIABP" ~ CRIT1FL + ), + PARAM = "Hypotension (mmHg)", + CRIT1 = case_when( + PARAMCD == "SYSBP" ~ "Systolic blood pressure <90", + PARAMCD == "DIABP" ~ "Diastolic blood pressure <60", + TRUE ~ as.character(CRIT1) + ) ) -} -# filtered_advs$PARAM <- droplevels(filtered_advs$PARAM) +#### create a label data frame to use in labels_map argument on analysis of each criteria flag +crit_cat <- sub("FL$", "", crit_flags) + +xlabel_map_sys <- unique(filtered_advs1 |> select(PARAM, all_of(crit_cat))) |> + tidyr::pivot_longer( + cols = all_of(crit_cat), + names_to = "var", + values_to = "label" + ) |> + filter(!is.na(label)) |> + mutate( + label = as.character(label), + var = paste0(var, "FL"), + value = "Y" + ) -filtered_advs <- var_relabel(filtered_advs, PARAM = "Blood Pressure") +xlabel_map_dia <- unique(filtered_advs2 |> select(PARAM, all_of(crit_cat))) |> + tidyr::pivot_longer( + cols = all_of(crit_cat), + names_to = "var", + values_to = "label" + ) |> + filter(!is.na(label)) |> + mutate( + label = as.character(label), + var = paste0(var, "FL"), + value = "Y" + ) + +### create a label data frame for Hypotension parameter for separate section +xlabel_map_hyps <- unique(filtered_advs3 |> filter(PARAMCD == selparamcd[1]) |> select(PARAM, CRIT1)) |> + tidyr::pivot_longer( + cols = c("CRIT1"), + names_to = "var", + values_to = "label" + ) |> + filter(!is.na(label)) |> + mutate( + label = as.character(label), + var = paste0(var, "FL_SYS"), + value = "Y" + ) + + +xlabel_map_hypd <- unique(filtered_advs3 |> filter(PARAMCD == selparamcd[2]) |> select(PARAM, CRIT1)) |> + tidyr::pivot_longer( + cols = c("CRIT1"), + names_to = "var", + values_to = "label" + ) |> + filter(!is.na(label)) |> + mutate( + label = as.character(label), + var = paste0(var, "FL_DIA"), + value = "Y" + ) ################################################################################ # Define layout and build table: ################################################################################ +extra_args1 <- list(denom = "n_df", riskdiff = FALSE, .stats = c("n_df")) extra_args_rr <- list( - method = "wald", denom = "n_df", + riskdiff = TRUE, + method = "wald", ref_path = ref_path, - .stats = c("denom", "count_unique_fraction") + .stats = c("count_unique_fraction") ) lyt0 <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels(ctrl_grp) - ) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt0 <- lyt0 |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt0 <- lyt0 |> + split_cols_by(trtvar) +} + +if (relrisk) { + lyt0 <- lyt0 |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels(ctrl_grp) + ) +} + +lyt1 <- lyt0 |> split_rows_by( "PARAM", label_pos = "topleft", - child_labels = "hidden", - split_label = "Systolic Blood Pressure (mmHg), n (%)", + parent_name = "PARAM_SD_N", + labels_var = "PARAM", + child_labels = "visible", + split_label = "Parameter, n (%)", section_div = " ", ## ensure only the appropriate levels inside PARAM-AVALCAT1 will be included - split_fun = trim_levels_to_map(param_map) + split_fun = trim_levels_in_group("PARAM") + ) |> + #### this assumes subjects always have both systolic and diastolic parameters + analyze( + "CRIT1FL", + a_freq_j, + show_labels = "hidden", + table_names = "CRIT1_SYS_N", + extra_args = extra_args1 + ) |> + # CRIT1FL + analyze( + crit_flags, + a_freq_j, + extra_args = append( + extra_args_rr, + list( + val = "Y", + label_map = xlabel_map_sys + ) + ), + indent_mod = 1L, + show_labels = "hidden" ) -# version without explicit denominator (as in shell) -lyt <- lyt0 %>% - # for testing, it is sometimes convenient to explicitely show the used denominator +lyt2 <- lyt0 |> + split_rows_by( + "PARAM", + label_pos = "topleft", + parent_name = "PARAM_SD_N", + labels_var = "PARAM", + child_labels = "visible", + split_label = "Parameter, n (%)", + section_div = " ", + ## ensure only the appropriate levels inside PARAM-AVALCAT1 will be included + split_fun = trim_levels_in_group("PARAM") + ) |> + #### this assumes subjects always have both systolic and diastolic parameters + analyze( + "CRIT1FL", + a_freq_j, + show_labels = "hidden", + table_names = "CRIT1_DIA_N", + extra_args = extra_args1 + ) |> + # CRIT1FL + analyze( + crit_flags, + a_freq_j, + extra_args = append( + extra_args_rr, + list( + val = "Y", + label_map = xlabel_map_dia + ) + ), + indent_mod = 1L, + show_labels = "hidden" + ) + +lyt3 <- lyt0 |> + split_rows_by( + "PARAM", + label_pos = "topleft", + parent_name = "PARAM_HYP_N", + labels_var = "PARAM", + child_labels = "visible", + split_label = "Parameter, n (%)", + section_div = " ", + ## ensure only the appropriate levels inside PARAM-AVALCAT1 will be included + split_fun = drop_split_levels + ) |> + #### this assumes subjects always have both systolic and diastolic parameters analyze( - "AVALCAT1", + "CRIT1FL", a_freq_j, - extra_args = extra_args_rr, show_labels = "hidden", - indent_mod = 0L + table_names = "CRIT1_HYP_N", + extra_args = extra_args1 + ) |> + # CRIT1FL_SYS + analyze( + "CRIT1FL_SYS", + a_freq_j, + extra_args = append( + extra_args_rr, + list( + val = "Y", + label_map = xlabel_map_hyps + ) + ), + indent_mod = 1L, + show_labels = "hidden" + ) |> + # CRIT1FL_DIA + analyze( + "CRIT1FL_DIA", + a_freq_j, + extra_args = append( + extra_args_rr, + list( + val = "Y", + label_map = xlabel_map_hypd + ) + ), + indent_mod = 1L, + show_labels = "hidden" ) -result <- build_table(lyt, filtered_advs, alt_counts_df = adsl) +result_s1 <- build_table(lyt1, df = filtered_advs1, alt_counts_df = adsl, round_type = "sas") +result_s2 <- build_table(lyt2, df = filtered_advs2, alt_counts_df = adsl, round_type = "sas") +result_s3 <- build_table(lyt3, df = filtered_advs3, alt_counts_df = adsl, round_type = "sas") +## stacking layout of two sections with different subset +result <- rtables::rbind(result_s1, result_s2, result_s3) ################################################################################ # Post-Processing: # - remove unwanted colcounts @@ -254,6 +391,7 @@ result <- set_titles(result, titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(24, 21, 21, 21, 33, 33) + +colwidth <- c(64, 21, 21, 21, 33, 33) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsfvit03.R b/tests/testthat/source_code/tsfvit03.R index 4fd83a82..2988ea44 100644 --- a/tests/testthat/source_code/tsfvit03.R +++ b/tests/testthat/source_code/tsfvit03.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfvit03 -## R version: 4.2.1 -## Short Description: Program to create tsfvit03: Subjects With Maximum -## On-treatment Diastolic Blood Pressure by Category of Blood Pressure -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, advs.RDS -## Output: tsfvit03.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -44,34 +20,69 @@ popfl <- "SAFFL" trtvar <- "TRT01A" ctrl_grp <- "Placebo" -selparamcd <- c("SYSBP", "DIABP") - -### tsfvit02 -# selparamcd <- c("SYSBP") - -### tsfvit03 : no code updates needed -selparamcd <- c("DIABP") +selparamcd <- c("SYSBP", "DIABP", "PULSE") ### as in dataset, order is important for later processing ### not automated, hard coded approach for ease of reading ### ideally the datasets already contain the appropriate case, to ensure units are in proper case -sel_param <- c("Diastolic Blood Pressure (mmHg)") -sel_param_case <- c("Diastolic blood pressure (mmHg)") +sel_param <- c( + "Systolic Blood Pressure (mmHg)", + "Diastolic Blood Pressure (mmHg)", + "Pulse Rate (beats/min)" +) +sel_param_case <- c( + "Systolic blood pressure (mmHg)", + "Diastolic blood pressure (mmHg)", + "Pulse rate (beats/min)" +) + +## different variants of table +over_time <- TRUE # over time analysis, ALSO restricted to on-treatment records +worst <- TRUE # analysis of min/max value, restricted to on-treatment records +## you can set both worst and over_time to TRUE, the "worst" timepoint will be shown first +treatment_emergent <- TRUE # only consider te values + +relrisk <- FALSE +# by default JJCS there is no need to add relative risk columns + +combined_colspan_trt <- FALSE + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select( - USUBJID, - all_of(c(popfl, trtvar)), - SEX_DECODE, - AGEGR1, - RACE_DECODE, - ETHNIC_DECODE - ) +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select(USUBJID, all_of(c(popfl, trtvar)), SEX, AGEGR1, RACE, ETHNIC) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), @@ -89,95 +100,178 @@ colspan_trt_map <- create_colspan_map( colspan_var = "colspan_trt", trt_var = trtvar ) - ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) -### note: by filter ANL06FL, this table is restricted to On-treatment values, per definition of ANL06FL -### therefor, no need to add ONTRTFL in filter -### if derivation of ANL06FL is not restricted to ONTRTFL records, adding ONTRTFL here will not give the correct answer either -### as mixing worst with other period is not giving the proper selection !!! -filtered_advs <- advs_jnj %>% - filter(PARAMCD %in% selparamcd) %>% - filter(ANL06FL == "Y") %>% - select( - STUDYID, - USUBJID, - PARAMCD, - PARAM, - AVALCAT1, - AVALCA1N, - AVISIT, - ANL06FL, - APOBLFL, - ONTRTFL - ) %>% - inner_join(adsl) +### for analysis of treatment emergent flag, do not use TRTEMFL as filter, as this will not give the proper denominator + +if (over_time) { + ## Version 1 : over time + filtered_advs_1 <- advs_jnj |> + filter(PARAMCD %in% selparamcd) |> + filter(ANL02FL == "Y") |> + ### note regarding ONTRTFL --- Per agreement on June 17 : On treatment over time : Filter on ONTRTFL as well + ### updated APOBLFL instead of ONTRTFL as per annotation update + ### Apr 2026: updated code to consider ONTRTFL instead of APOBLFL flag as per annotation + filter(ONTRTFL == "Y") |> + select( + STUDYID, + USUBJID, + PARAMCD, + PARAM, + PARAMN, + AVALCAT1, + AVALCA1N, + AVISIT, + AVISITN, + ONTRTFL, + APOBLFL, + CRIT7, + CRIT7FL, + CRIT8, + CRIT8FL, + TRTEMFL, + ANL02FL, + AVAL + ) |> + inner_join(adsl) +} + +if (worst) { + ## Version 2 : "worst analysis" -- ANL03FL (max) ANL06FL (min) + + ### note: by filter ANL06FL/ANL03FL, this table is restricted to On-treatment values, per definition of ANL06FL/ANL03FL + ### therefore, no need to add ONTRTFL in filter + ### if derivation of ANL06FL is not restricted to ONTRTFL records, adding ONTRTFL here will not give the correct answer either + ### as mixing worst with other period is not giving the proper selection !!! + ### June 2026: Added additional filter on ONTRTFL as per annotation + + filtered_advs_2 <- advs_jnj |> + filter(PARAMCD %in% selparamcd) |> + # 2 records per subject selected : min (ANL06) / max (ANL03) + filter(ANL03FL == "Y" | ANL06FL == "Y" & ONTRTFL == "Y") |> + select( + STUDYID, + USUBJID, + PARAMCD, + PARAM, + PARAMN, + AVALCAT1, + AVALCA1N, + AVISIT, + AVISITN, + APOBLFL, + CRIT7, + CRIT7FL, + CRIT8, + CRIT8FL, + TRTEMFL, + ANL03FL, + ANL06FL, + AVAL + ) |> + inner_join(adsl) + + ### need to check for your study if the below applies as these can be study specific + ## for CRIT7 : use minimum (ANL06FL) - disregard the record if it was not coming from MIN + ## for CRIT8 : use maximum (ANL03FL) - disregard the record if it was not coming from MAX + ## 1 record per subjects with non-missing CRIT7FL + ## 1 record per subjects with non-missing CRIT8FL + ## these will be over 2 different records + filtered_advs_2 <- filtered_advs_2 |> + mutate( + CRIT7FL = case_when( + ANL06FL == "N" ~ NA, + TRUE ~ CRIT7FL + ), + CRIT8FL = case_when( + ANL03FL == "N" ~ NA, + TRUE ~ CRIT8FL + ) + ) |> + # On-treatment records assigned visit number 00 to display first in ordering + mutate(AVISIT = "On-treatment", AVISITN = 00) +} + + +if (over_time & worst) { + filtered_advs <- bind_rows( + filtered_advs_1, + filtered_advs_2 + ) +} else if (over_time) { + filtered_advs <- filtered_advs_1 +} else if (worst) { + filtered_advs <- filtered_advs_2 +} else { + stop("At least worst or over_time should be set to TRUE") +} filtered_advs$PARAM <- factor( as.character(filtered_advs$PARAM), levels = sel_param, labels = sel_param_case ) +### reorder AVISIT factor levels by it's AVISTN order +filtered_advs$AVISIT <- factor( + as.character(filtered_advs$AVISIT), + levels = unique(filtered_advs[["AVISIT"]])[order(unique(filtered_advs[["AVISITN"]]))] +) +### for analysis of treatment emergent abnormalities only : +### per discussion with DAS team: denominator is still the subjects with evaluation of CRIT7FL/CRIT8FL, +### there is no need to get baseline status to exclude subjects with an abnormal baseline status +### the only thing that should be done is : non-treatment emergent abnormalities should not be reported in the numerator, only in denom +### this can be done using the following code + +if (treatment_emergent) { + filtered_advs <- filtered_advs |> + mutate( + CRIT7FL = case_when( + CRIT7FL == "Y" & (is.na(TRTEMFL) | TRTEMFL != "Y") ~ "N", + TRUE ~ CRIT7FL + ), + CRIT8FL = case_when( + CRIT8FL == "Y" & (is.na(TRTEMFL) | TRTEMFL != "Y") ~ "N", + TRUE ~ CRIT8FL + ) + ) +} -################################################################################ -# Process markedly abnormal values from spreadsheet: -################################################################################ +### converting CRIT7FL/CRIT8FL to factor for use in label maps on layout +filtered_advs$CRIT7FL <- factor( + as.character(filtered_advs$CRIT7FL), + levels = c("Y", "N") +) -### Markedly Abnormal spreadsheet - -markedlyabnormal_file <- file.path(datapath, "markedlyabnormal.xlsx") - - - - -lbmarkedlyabnormal_defs <- readxl::read_excel( - markedlyabnormal_file, - sheet = "ADVS" -) %>% - filter(PARAMCD != "Parameter Code") %>% - arrange(PARAMCD, VARNAME, ORDER) %>% - filter(VARNAME == "AVALCAT1") %>% - filter(PARAMCD %in% selparamcd) %>% - left_join(., unique(filtered_advs %>% select(PARAMCD, PARAM))) - - -# code_decode <- getcodelistinfo(df=filtered_advs, -# domain="advs", -# vars = c("AVALCAT1"), -# APT= apt, -# adam_meta_loc=am_in, -# sdtm_meta_loc=dm_in) -# -# -# code_decode <- code_decode %>% -# filter(PARAMCD %in% selparamcd) %>% -# left_join(.,unique(filtered_advs %>% select(PARAMCD,PARAM))) - -### create a mapping table for usage in split_fun trim_levels_to_map, -### to ensure only the levels appropriate for the selected parameters are covered - -param_map <- lbmarkedlyabnormal_defs %>% - rename(AVALCAT1 = CRIT) %>% - ### no factors are allowed in this split_fun map definition - mutate(PARAM = as.character(PARAM)) %>% - select(PARAM, AVALCAT1) - -# if no code list was defined, not all defined categories might be present on data -# sas2rds conversion might not have added all categories as factor levels - need to do this here -if ( - class(filtered_advs$AVALCAT1) == "character" || - !all(unique(param_map$AVALCAT1) %in% levels(filtered_advs$AVALCAT1)) -) { - filtered_advs$AVALCAT1 <- factor( - as.character(filtered_advs$AVALCAT1), - levels = unique(param_map$AVALCAT1) - ) -} +filtered_advs$CRIT8FL <- factor( + as.character(filtered_advs$CRIT8FL), + levels = c("Y", "N") +) -# filtered_advs$PARAM <- droplevels(filtered_advs$PARAM) +filtered_advs$PARAM <- factor( + filtered_advs$PARAM, + levels = unique(filtered_advs[["PARAM"]])[order(unique(filtered_advs[["PARAMN"]]))] +) -filtered_advs <- var_relabel(filtered_advs, PARAM = "Blood Pressure") +filtered_advs$AVISIT <- factor( + filtered_advs$AVISIT, + levels = unique(filtered_advs[["AVISIT"]])[order(unique(filtered_advs[["AVISITN"]]))] +) + +### Mapping for CRIT7&CRIT8 +### alternative approach to retrieve from metadata iso dataset - +xlabel_map <- unique(filtered_advs |> select(PARAM, CRIT7, CRIT8)) |> + tidyr::pivot_longer( + cols = c("CRIT7", "CRIT8"), + names_to = "var", + values_to = "label" + ) |> + filter(!is.na(label)) |> + mutate( + label = as.character(label), + var = paste0(var, "FL"), + value = "Y" + ) ################################################################################ # Define layout and build table: @@ -187,53 +281,89 @@ extra_args_rr <- list( method = "wald", denom = "n_df", ref_path = ref_path, - .stats = c("denom", "count_unique_fraction") + .stats = c("count_unique_fraction") ) - -lyt0 <- basic_table( +lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels(ctrl_grp) - ) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (relrisk) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels(ctrl_grp) + ) +} + +lyt <- lyt |> + split_rows_by( + "AVISIT", + label_pos = "topleft", + child_labels = "visible", + split_label = "Study Visit", + split_fun = drop_split_levels, + section_div = " " + ) |> split_rows_by( "PARAM", label_pos = "topleft", - child_labels = "hidden", - split_label = "Diastolic Blood Pressure (mmHg), n (%)", - section_div = " ", - ## ensure only the appropriate levels inside PARAM-AVALCAT1 will be included - split_fun = trim_levels_to_map(param_map) - ) - -# version without explicit denominator (as in shell) -lyt <- lyt0 %>% - # for testing, it is sometimes convenient to explicitely show the used denominator + child_labels = "visible", + split_label = "Parameter", + split_fun = drop_split_levels, + section_div = " " + ) |> + summarize_row_groups( + "AVISIT", + cfun = a_freq_j, + extra_args = list( + .stats = "n_df", + label = "N", + riskdiff = FALSE + ) + ) |> analyze( - "AVALCAT1", + c("CRIT7FL", "CRIT8FL"), a_freq_j, - extra_args = extra_args_rr, + extra_args = append( + extra_args_rr, + list(val = c("Y"), label_map = xlabel_map) + ), show_labels = "hidden", - indent_mod = 0L - ) + indent_mod = 1L + ) |> + append_topleft(" Criteria, n (%)") - -result <- build_table(lyt, filtered_advs, alt_counts_df = adsl) +result <- build_table(lyt, filtered_advs, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: # - remove unwanted colcounts ################################################################################ +if (over_time) { + visit_list <- unique(as.character(filtered_advs$AVISIT)) + + for (i in seq_along(visit_list)) { + section_div_at_path(result, path = c("AVISIT", visit_list[[i]]), labelrow = TRUE) <- " " + } +} else { + section_div_at_path(result, path = c("PARAM", "*", "CRIT8FL"), labelrow = TRUE) <- " " +} result <- remove_col_count(result) @@ -247,6 +377,7 @@ result <- set_titles(result, titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(24, 21, 21, 21, 31, 31) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(64, 7, 7, 7) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfvit04.R b/tests/testthat/source_code/tsfvit04.R index bebc0032..9ac6d9c7 100644 --- a/tests/testthat/source_code/tsfvit04.R +++ b/tests/testthat/source_code/tsfvit04.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfvit04 -## R version: 4.2.1 -## Short Description: Program to create tsfvit04: Subjects Meeting Specific -## On-treatment Hypotension Levels -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, advs.RDS -## Output: tsfvit04.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -44,28 +20,61 @@ popfl <- "SAFFL" trtvar <- "TRT01A" ctrl_grp <- "Placebo" -selparamcd <- c("SYSBP", "DIABP") -### as in dataset, order is important for later processing -### not automated, hard coded approach for ease of reading -### ideally the datasets already contain the appropriate case, to ensure units are in proper case -sel_param <- c( - "Systolic Blood Pressure (mmHg)", - "Diastolic Blood Pressure (mmHg)" -) -sel_param_case <- c( - "Systolic blood pressure (mmHg)", - "Diastolic blood pressure (mmHg)" -) +# flag to indclude timepoint rows +over_time <- TRUE + +# only consider TE values +treatment_emergent <- FALSE + +relrisk <- FALSE +# by default JJCS there is no need to add relative risk columns + +combined_colspan_trt <- FALSE + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +# specify in the order you want to print on table +selparamcd <- c("ORTHYP", "ORTHYPS", "ORTHYPD") + +selparamcdN <- tibble(PARAMCD = selparamcd, PARAMCDN = seq_along(selparamcd)) + +### Per email June 12: DAS/SDS confirmed to NOT restrict to on-treatment values ################################################################################ # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(c(popfl, trtvar)), SEX, AGEGR1, RACE, ETHNIC) - adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), levels = c("Active Study Agent", " ") @@ -85,98 +94,212 @@ colspan_trt_map <- create_colspan_map( ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) -### add On-treatment restriction -filtered_advs <- advs_jnj %>% - filter(PARAMCD %in% selparamcd) %>% - ### as this table is using CRIT3 and not a flag like ANL03FL - ### we need to explicitely apply filter ONTRTFL to restrict to On-treatment - filter(ONTRTFL == "Y") %>% +### N is the number of subjects with postbaseline orthostatic measurements and without orthostatic hypotension at baseline +## do not use TRTEMFL as filter, as this will only select AVALC = Y records per definition of TRTEMFL +## instead : start from post-baseline records and retain one record per subject +## for those subjects with both Y and N records, keep the Y record +## for those subjects with only Y records or only N records, keep one Y, N record respectively +filtered_advs_1 <- advs_jnj |> + filter(PARAMCD %in% selparamcd & ONTRTFL == "Y") |> select( STUDYID, USUBJID, PARAMCD, PARAM, - AVALCAT1, - AVALCA1N, AVISIT, + AVISITN, APOBLFL, - CRIT3, - CRIT3FL, - ONTRTFL - ) %>% - inner_join(adsl) %>% + TRTEMFL, + CRIT1, + CRIT1FL, + ONTRTFL, + AVALC + ) |> + inner_join(adsl) |> ### ensure to keep only 1 result per subject, keep N only in case no Y was observed - arrange(USUBJID, PARAMCD, CRIT3, CRIT3FL) %>% - group_by(USUBJID, PARAMCD) %>% - mutate(ncrit3 = n_distinct(CRIT3FL)) %>% - filter(!(ncrit3 > 1 & CRIT3FL == "N")) %>% + arrange(USUBJID, PARAMCD, AVALC, CRIT1, CRIT1FL) |> + group_by(USUBJID, PARAMCD) |> + mutate(ncrit1 = n_distinct(CRIT1FL)) |> + filter(!(ncrit1 > 1 & CRIT1FL == "N")) |> ## only keep one record - slice_head(n = 1) %>% - ungroup() + slice_head(n = 1) |> + ungroup() |> + # On-treatment records assigned visit number 00 to display first in ordering + mutate(AVISIT = "On-treatment", AVISITN = 00) + +if (over_time) { + filtered_advs_2 <- advs_jnj |> + filter(PARAMCD %in% selparamcd & ONTRTFL == "Y") |> + select( + STUDYID, + USUBJID, + PARAMCD, + PARAM, + AVISIT, + AVISITN, + APOBLFL, + TRTEMFL, + CRIT1, + CRIT1FL, + ONTRTFL, + AVALC + ) |> + inner_join(adsl) |> + ### ensure to keep only 1 result per subject, keep N only in case no Y was observed + arrange(USUBJID, PARAMCD, AVISIT, AVALC, CRIT1, CRIT1FL) |> + group_by(USUBJID, PARAMCD, AVISIT) |> + mutate(ncrit1 = n_distinct(CRIT1FL)) |> + filter(!(ncrit1 > 1 & CRIT1FL == "N")) |> + ## only keep one record + slice_head(n = 1) |> + ungroup() +} +if (over_time) { + filtered_advs <- bind_rows( + filtered_advs_1, + filtered_advs_2 + ) +} else { + filtered_advs <- filtered_advs_1 +} + +### reorder AVISIT factor levels by it's AVISTN order +filtered_advs$AVISIT <- factor( + as.character(filtered_advs$AVISIT), + levels = unique(filtered_advs[["AVISIT"]])[order(unique(filtered_advs[["AVISITN"]]))] +) + +#### remove subjects abnormal for "ORTHYP","ORTHYPS" & "ORTHYPD" at baseline +bl_abn_orthyp <- advs_jnj |> + filter(PARAMCD %in% c("ORTHYP", "ORTHYPS", "ORTHYPD") & ABLFL == "Y" & AVALC == "Y") + +### actually remove the subjects with AVALC = Y for ORTHYP +### N is the number of subjects with postbaseline orthostatic measurements and without orthostatic hypotension at baseline +filtered_advs <- filtered_advs |> + filter(!(USUBJID %in% unique(bl_abn_orthyp$USUBJID))) |> + ### For ORTHYP parameter AVALC='Y' should be considered and CRIT1FL considered for ORTHYPS & ORTHYPD as per annotation + mutate( + CRIT1FL = case_when( + AVALC == "Y" & PARAMCD == "ORTHYP" ~ "Y", + TRUE ~ CRIT1FL + ) + ) + +if (treatment_emergent) { + filtered_advs <- filtered_advs |> + mutate( + CRIT1FL = case_when( + CRIT1FL == "Y" & (is.na(TRTEMFL) | TRTEMFL != "Y") ~ "N", + TRUE ~ CRIT1FL + ) + ) +} + +### get sorting as per order in selparamcdN +selparamcdN <- selparamcdN |> + left_join(unique(filtered_advs |> select(PARAMCD, PARAM))) |> + arrange(PARAMCDN) + +param_levels <- unique(as.character(selparamcdN$PARAM)) filtered_advs$PARAM <- factor( as.character(filtered_advs$PARAM), - levels = sel_param, - labels = sel_param_case + levels = param_levels +) +### converting CRIT1FL to factor for use in label maps on layout +filtered_advs$CRIT1FL <- factor( + as.character(filtered_advs$CRIT1FL) ) - -### Mapping for CRIT3 +### Mapping for AVALC ### alternative approach to retrieve from metadata iso dataset -xlabel_map <- unique(filtered_advs %>% select(PARAM, CRIT3)) %>% - rename(label = CRIT3) %>% +xlabel_map <- unique(filtered_advs |> select(PARAM, PARAMCD, CRIT1)) |> + tidyr::pivot_longer( + cols = c("CRIT1"), + names_to = "var", + values_to = "label" + ) |> + filter(!is.na(label)) |> + mutate( + label = as.character(label), + var = paste0(var, "FL"), + value = "Y" + ) |> mutate( - value = "Y", - label = as.character(label) + label = case_when( + label == "SBP (STD-SUP)<-20 or DBP (STD-SUP)<-10" ~ "Total number of subjects with orthostatic hypotension", + TRUE ~ label + ) ) ################################################################################ # Define layout and build table: ################################################################################ -extra_args1 <- list(denom = "n_df", riskdiff = FALSE, .stats = c("n_df")) extra_args_rr <- list( - denom = "n_df", - riskdiff = TRUE, method = "wald", + denom = "n_df", ref_path = ref_path, .stats = c("count_unique_fraction") ) - lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels(ctrl_grp) - ) %>% - #### this assumes subjects always have both systolic and diastolic parameters - analyze( - "CRIT3FL", - a_freq_j, - show_labels = "hidden", - table_names = "CRIT3_N", - extra_args = extra_args1 - ) %>% + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> + split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> + split_cols_by(trtvar) +} + +if (relrisk) { + lyt <- lyt |> + split_cols_by("rrisk_header", nested = FALSE) |> + split_cols_by( + trtvar, + labels_var = "rrisk_label", + split_fun = remove_split_levels(ctrl_grp) + ) +} + +lyt <- lyt |> + split_rows_by( + "AVISIT", + label_pos = "topleft", + split_fun = drop_split_levels, + child_labels = "visible", + split_label = " ", + section_div = " " + ) |> + summarize_row_groups( + "AVISIT", + cfun = a_freq_j, + extra_args = list( + .stats = "n_df", + label = "N", + riskdiff = FALSE + ) + ) |> split_rows_by( "PARAM", label_pos = "topleft", + split_fun = drop_split_levels, child_labels = "hidden", - split_label = paste("Blood Pressure (mmHg), n (%)") - ) %>% + split_label = "Orthostatic Hypotension, n (%)" + ) |> analyze( - "CRIT3FL", + "CRIT1FL", a_freq_j, + table_names = "CRIT1_V1", extra_args = append( extra_args_rr, list( @@ -188,13 +311,33 @@ lyt <- basic_table( show_labels = "hidden" ) -result <- build_table(lyt, filtered_advs, alt_counts_df = adsl) +result <- build_table(lyt, filtered_advs, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: +# - update indent for "SYSBPO" and "DIABPO" # - remove unwanted colcounts ################################################################################ +## update indent for "ORTHYPS" and "ORTHYPD" +adj_indent_mod <- function(result, path, indentupd) { + indent_mod(tt_at_path(result, path)) <- indent_mod(tt_at_path(result, path)) + + indentupd + return(result) +} + +avisit_ind <- unique(as.character(filtered_advs$AVISIT)) + +for (i in seq_along(avisit_ind)) { + path_ <- c("AVISIT", avisit_ind[[i]], "PARAM", "Orthostatic Hypotension") + + result <- adj_indent_mod( + result, + path = path_, + indentupd = -1L + ) +} + result <- remove_col_count(result) ################################################################################ @@ -207,6 +350,7 @@ result <- set_titles(result, titles) # Convert to tbl file and output table ################################################################################ -colwidth <- c(48, 19, 19, 19, 33, 33) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(64, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfvit05.R b/tests/testthat/source_code/tsfvit05.R deleted file mode 100644 index 15ec4cfd..00000000 --- a/tests/testthat/source_code/tsfvit05.R +++ /dev/null @@ -1,344 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfvit05 -## R version: 4.2.1 -## Short Description: Program to create tsfvit05: Subjects With -## On-treatment Clinically Important Vital Signs [Over Time] -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, advs.RDS -## Output: tsfvit05.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFVIT05" -fileid <- write_path(opath, tblid) -titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -popfl <- "SAFFL" -trtvar <- "TRT01A" -ctrl_grp <- "Placebo" - -selparamcd <- c("PULSE", "SYSBP", "DIABP") - -selvisit <- c("Cycle 02", "Cycle 04") - -### as in dataset, order is important for later processing -### not automated, hard coded approach for ease of reading -### ideally the datasets already contain the appropriate case, to ensure units are in proper case -sel_param <- c( - "Pulse Rate (beats/min)", - "Systolic Blood Pressure (mmHg)", - "Diastolic Blood Pressure (mmHg)" -) -sel_param_case <- c( - "Pulse rate (beats/min)", - "Systolic blood pressure (mmHg)", - "Diastolic blood pressure (mmHg)" -) - -## different variants of table -over_time <- TRUE # over time analysis, ALSO restricted to on-treatment records -worst <- TRUE # analysis of min/max value, restricted to on-treatment records -## you can set both worst and over_time to TRUE, the "worst" timepoint will be shown first -treatment_emergent <- FALSE # only consider te values - -relrisk <- FALSE -# by default JJCS there is no need to add relative risk columns - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select(USUBJID, all_of(c(popfl, trtvar)), SEX, AGEGR1, RACE, ETHNIC) - - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -adsl$rrisk_header <- "Risk Difference (%) (95% CI)" -adsl$rrisk_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - -### for analysis of treatment emergent flag, do not use TRTEMFL as filter, as this will not give the proper denominator - -if (over_time) { - ## Version 1 : over time - filtered_advs_1 <- advs_jnj %>% - filter(PARAMCD %in% selparamcd) %>% - filter(AVISIT %in% selvisit) %>% - filter(ANL02FL == "Y") %>% - ### note regarding ONTRTFL --- Per agreement on June 17 : On treatment over time : Filter on ONTRTFL as well - ### - filter(ONTRTFL == "Y") %>% - select( - STUDYID, - USUBJID, - PARAMCD, - PARAM, - AVALCAT1, - AVALCA1N, - AVISIT, - ONTRTFL, - APOBLFL, - CRIT1, - CRIT1FL, - CRIT2, - CRIT2FL, - TRTEMFL, - ANL02FL, - AVAL - ) %>% - inner_join(adsl) -} - -if (worst) { - ## Version 2 : "worst analysis" -- ANL03FL (max) ANL06FL (min) - - ### note: by filter ANL06FL/ANL03FL, this table is restricted to On-treatment values, per definition of ANL06FL/ANL03FL - ### therefor, no need to add ONTRTFL in filter - ### if derivation of ANL06FL is not restricted to ONTRTFL records, adding ONTRTFL here will not give the correct answer either - ### as mixing worst with other period is not giving the proper selection !!! - - filtered_advs_2 <- advs_jnj %>% - filter(PARAMCD %in% selparamcd) %>% - # 2 records per subject selected : min (ANL06) / max (ANL03) - filter(ANL03FL == "Y" | ANL06FL == "Y") %>% - select( - STUDYID, - USUBJID, - PARAMCD, - PARAM, - AVALCAT1, - AVALCA1N, - AVISIT, - APOBLFL, - CRIT1, - CRIT1FL, - CRIT2, - CRIT2FL, - TRTEMFL, - ANL03FL, - ANL06FL, - AVAL - ) %>% - inner_join(adsl) - - ### need to check for your study if the below applies as these can be study specific - ## for CRIT1 : use minimum (ANL06FL) - disregard the record if it was not coming from MIN - ## for CRIT2 : use maximum (ANL03FL) - disregard the record if it was not coming from MAX - ## 1 record per subjects with non-missing CRIT1FL - ## 1 record per subjects with non-missing CRIT2FL - ## these will be over 2 different records - filtered_advs_2 <- filtered_advs_2 %>% - mutate( - CRIT1FL = case_when( - ANL06FL == "N" ~ NA, - TRUE ~ CRIT1FL - ), - CRIT2FL = case_when( - ANL03FL == "N" ~ NA, - TRUE ~ CRIT2FL - ) - ) %>% - mutate(AVISIT = "On-treatment") -} - - -if (over_time & worst) { - filtered_advs <- bind_rows( - filtered_advs_1, - filtered_advs_2 - ) - - filtered_advs$AVISIT <- factor( - as.character(filtered_advs$AVISIT), - levels = c("On-treatment", levels(filtered_advs_1$AVISIT)) - ) -} else if (over_time) { - filtered_advs <- filtered_advs_1 -} else if (worst) { - filtered_advs <- filtered_advs_2 -} else { - stop("At least worst or over_time should be set to TRUE") -} - -filtered_advs$PARAM <- factor( - as.character(filtered_advs$PARAM), - levels = sel_param, - labels = sel_param_case -) - -### for analysis of treatment emergent abnormalities only : -### per discussion with DAS team: denominator is still the subjects with evaluation of CRIT1FL/CRIT2FL, -### there is no need to get baseline status to exclude subjects with an abnormal baseline status -### the only thing that should be done is : non-treatment emergent abnormalities should not be reported in the numerator, only in denom -### this can be done using the following code - -if (treatment_emergent) { - filtered_advs <- filtered_advs %>% - mutate( - CRIT1FL = case_when( - CRIT1FL == "Y" & (is.na(TRTEMFL) | TRTEMFL != "Y") ~ "N", - TRUE ~ CRIT1FL - ), - CRIT2FL = case_when( - CRIT2FL == "Y" & (is.na(TRTEMFL) | TRTEMFL != "Y") ~ "N", - TRUE ~ CRIT2FL - ) - ) -} - - -filtered_advs <- var_relabel(filtered_advs, PARAM = "Blood Pressure (mmHg)") - - -### Mapping for CRIT1&CRIT2 -### alternative approach to retrieve from metadata iso dataset - -xlabel_map <- unique(filtered_advs %>% select(PARAM, CRIT1, CRIT2)) %>% - tidyr::pivot_longer( - cols = c("CRIT1", "CRIT2"), - names_to = "var", - values_to = "label" - ) %>% - filter(!is.na(label)) %>% - mutate( - label = as.character(label), - var = paste0(var, "FL"), - value = "Y" - ) - -################################################################################ -# Define layout and build table: -################################################################################ - -extra_args_rr <- list( - method = "wald", - denom = "n_df", - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - - -lyt <- basic_table( - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) - - -if (relrisk) { - lyt <- lyt %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels(ctrl_grp) - ) -} - -if (over_time) { - lyt <- lyt %>% - split_rows_by( - "AVISIT", - label_pos = "topleft", - child_labels = "visible", - split_label = "Study Visit", - split_fun = drop_split_levels, - section_div = " " - ) -} - -lyt <- lyt %>% - split_rows_by( - "PARAM", - label_pos = "topleft", - child_labels = "visible", - split_label = "Parameter", - split_fun = drop_split_levels, - section_div = " " - ) %>% - analyze( - "CRIT1FL", - a_freq_j, - show_labels = "hidden", - table_names = "CRIT1_N", - extra_args = list(denom = "n_df", .stats = c("n_df")) - ) %>% - analyze( - c("CRIT1FL", "CRIT2FL"), - a_freq_j, - extra_args = append( - extra_args_rr, - list(val = c("Y"), label_map = xlabel_map) - ), - show_labels = "hidden", - indent_mod = 1L - ) %>% - append_topleft(" Criteria, n (%)") - - -result <- build_table(lyt, filtered_advs, alt_counts_df = adsl) - -################################################################################ -# Post-Processing: -# - remove unwanted colcounts -################################################################################ - -result <- remove_col_count(result) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 7, 17, 17) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsfvit06.R b/tests/testthat/source_code/tsfvit06.R deleted file mode 100644 index 5f0f5647..00000000 --- a/tests/testthat/source_code/tsfvit06.R +++ /dev/null @@ -1,246 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsfvit06 -## R version: 4.2.1 -## Short Description: Program to create tsfvit06: Subjects With -## Treatment-emergent Orthostatic Hypotension During -## [Treatment Period] -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, advs.RDS -## Output: tsfvit06.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -tblid <- "TSFVIT06" -fileid <- write_path(opath, tblid) -titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -popfl <- "SAFFL" -trtvar <- "TRT01A" -ctrl_grp <- "Placebo" - -# specify in the order you want to print on table -selparamcd <- c("ORTHYP", "DIABPO", "SYSBPO") - -selparamcdN <- tibble(PARAMCD = selparamcd, PARAMCDN = seq_along(selparamcd)) - -### Per email June 12: DAS/SDS confirmed to NOT restrict to on-treatment values - -################################################################################ -# Process Data: -################################################################################ - -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select(USUBJID, all_of(c(popfl, trtvar)), SEX, AGEGR1, RACE, ETHNIC) - - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - -### N is the number of subjects with postbaseline orthostatic measurements and without orthostatic hypotension at baseline -## do not use TRTEMFL as filter, as this will only select AVALC = Y records per definition of TRTEMFL -## instead : start from post-baseline records and retain one record per subject -## for those subjects with both Y and N records, keep the Y record -## for those subjects with only Y records or only N records, keep one Y, N record respectively -filtered_advs <- advs_jnj %>% - filter(PARAMCD %in% selparamcd & APOBLFL == "Y") %>% - filter(PARAMCD %in% selparamcd) %>% - mutate( - AVALC = case_when( - (PARAMCD == "SYSBPO" | PARAMCD == "DIABPO") & CRIT1FL == "Y" ~ "Y", - (PARAMCD == "SYSBPO" | PARAMCD == "DIABPO") & - (CRIT1FL == "N" | - CRIT1FL == NA) ~ "N", - PARAMCD == "ORTHYP" ~ AVALC - ), - PARAM = case_when( - PARAMCD == "SYSBPO" ~ "SBP (STD-SUP) <-20", - PARAMCD == "DIABPO" ~ "DBP (STD-SUP) <-10", - PARAMCD == "ORTHYP" ~ PARAM - ) - ) %>% - select( - STUDYID, - USUBJID, - PARAMCD, - PARAM, - AVALC, - AVISIT, - APOBLFL, - TRTEMFL, - ONTRTFL - ) %>% - inner_join(adsl) %>% - ### ensure to keep only 1 result per subject, keep N only in case no Y was observed - arrange(USUBJID, PARAMCD, AVALC) %>% - group_by(USUBJID, PARAMCD) %>% - mutate(navalc = n_distinct(AVALC)) %>% - filter(!(navalc > 1 & AVALC == "N")) %>% - ## only keep one record - slice_head(n = 1) %>% - ungroup() - -#### remove subjects abnormal for "ORTHYP" at baseline -bl_abn_orthyp <- advs_jnj %>% - filter(PARAMCD == "ORTHYP" & ABLFL == "Y" & AVALC == "Y") - -### actually remove the subjects with AVALC = Y for ORTHYP -### N is the number of subjects with postbaseline orthostatic measurements and without orthostatic hypotension at baseline -filtered_advs <- filtered_advs %>% - filter(!(USUBJID %in% unique(bl_abn_orthyp$USUBJID))) - -### get sorting as per order in selparamcdN -selparamcdN <- selparamcdN %>% - left_join(unique(filtered_advs %>% select(PARAMCD, PARAM))) %>% - arrange(PARAMCDN) - -param_levels <- unique(as.character(selparamcdN$PARAM)) - -filtered_advs$PARAM <- factor( - as.character(filtered_advs$PARAM), - levels = param_levels -) - - -### Mapping for AVALC -### alternative approach to retrieve from metadata iso dataset -xlabel_map <- unique(filtered_advs %>% select(PARAM, PARAMCD)) %>% - mutate( - value = "Y", - label = as.character(PARAM) - ) %>% - mutate( - label = case_when( - label == - "Orthostatic Hypotension" ~ "Total number of subjects with orthostatic hypotension", - TRUE ~ label - ) - ) - -################################################################################ -# Define layout and build table: -################################################################################ - -extra_args_rr <- list( - method = "wald", - denom = "n_df", - ref_path = ref_path, - .stats = c("count_unique_fraction") -) - -lyt <- basic_table( - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - analyze( - "AVALC", - a_freq_j, - show_labels = "hidden", - table_names = "AVALC_N", - extra_args = list(denom = "n_df", .stats = c("n_df")) - ) %>% - split_rows_by( - "PARAM", - label_pos = "topleft", - split_fun = drop_split_levels, - child_labels = "hidden", - split_label = "Orthostatic hypotension, n (%)" - ) %>% - # as in shell, do not show denom in count/denom (%) - ### indent will be fixed to 1, will be updated later in post-processing - analyze( - "AVALC", - a_freq_j, - extra_args = append( - extra_args_rr, - list( - val = c("Y"), - label_map = xlabel_map - ) - ), - indent_mod = 2L, - show_labels = "hidden" - ) - -result <- build_table(lyt, filtered_advs, alt_counts_df = adsl) - -################################################################################ -# Post-Processing: -# - update indent for "SYSBPO" and "DIABPO" -# - remove unwanted colcounts -################################################################################ - -## update indent for "SYSBPO" and "DIABPO" - -adj_indent_mod <- function(result, path, indentupd) { - indent_mod(tt_at_path(result, path)) <- indent_mod(tt_at_path(result, path)) + - indentupd - return(result) -} - -result <- adj_indent_mod( - result, - path = c("PARAM", "Orthostatic Hypotension"), - indentupd = -1L -) - -result <- remove_col_count(result) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ - -colwidth <- c(64, 21, 21, 21) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsicm01.R b/tests/testthat/source_code/tsicm01.R index ed04b4c5..01b1e254 100644 --- a/tests/testthat/source_code/tsicm01.R +++ b/tests/testthat/source_code/tsicm01.R @@ -1,33 +1,10 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsicm01.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsicm01: Concomitant Medications by -## ATC Level X/Standardized Medication Name - Variant 1 -## Author: Johnson & Johnson Innovative Medicine -## Date: 13 Nov 2023 -## Input: ADSL, ADCM. -## Output: TSICM01.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(tidyr) +library(stringr) ################################################################################ # Define script level parameters: @@ -54,8 +31,9 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" -atcvar <- "CMLVL1" -atclevel <- "1" +smnvar <- "CMDECOD" +atcvar <- c("CMLVL1", "CMLVL2", "CMLVL3", "CMLVL4") +atclevel <- c("1", "2", "3", "4") combined_colspan_trt <- TRUE @@ -78,33 +56,60 @@ if (combined_colspan_trt == TRUE) { mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) } -################################################################################ -# Process Data: -################################################################################ +# ################################################################################ +# # Process Data: +# ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(trtvar), all_of(popfl)) -adcm <- adcm_jnj %>% - filter(ONTRTFL == "Y") %>% - select(USUBJID, ONTRTFL, all_of(atcvar), CMDECOD) - -# Convert medications to sentence case -adcm[[atcvar]] <- as.factor(stringr::str_to_sentence(adcm[[atcvar]])) -adcm$CMDECOD <- as.factor(stringr::str_to_sentence(adcm$CMDECOD)) - +adcm <- adcm_jnj |> + filter(ONTRTFL == "Y") |> + select(USUBJID, CMTRT, ONTRTFL, all_of(atcvar), all_of(smnvar)) |> + mutate( + across( + all_of(atcvar), + ~ case_when( + .x == "" ~ "Uncoded", + .default = .x + ) + ), + across( + all_of(atcvar), + ~ str_to_sentence(.x) + ), + !!rlang::sym(smnvar) := case_when( + .data[[smnvar]] == "" ~ paste0("Uncoded: ", CMTRT), + .default = .data[[smnvar]] + ), + across( + all_of(smnvar), + ~ str_to_sentence(.x) + ) + ) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), levels = c("Active Study Agent", " ") ) # join data together -cm <- adcm %>% inner_join(., adsl, by = c("USUBJID")) +cm <- adcm |> inner_join(adsl, by = c("USUBJID")) + if (length(adcm$ONTRTFL) == 0) { - cm <- adcm %>% right_join(., adsl, by = c("USUBJID")) + cm <- adcm |> right_join(adsl, by = c("USUBJID")) } colspan_trt_map <- create_colspan_map( @@ -126,22 +131,22 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% - add_overall_col("Total") %>% +lyt <- lyt |> + add_overall_col("Total") |> analyze( "ONTRTFL", afun = a_freq_j, @@ -150,21 +155,30 @@ lyt <- lyt %>% extra_args_1, list(label = "Subjects with >=1 concomitant medication") ) - ) %>% - split_rows_by( - atcvar, - child_labels = "hidden", - split_label = paste0("ATC Level ", atclevel), - label_pos = "topleft", - split_fun = trim_levels_in_group("CMDECOD"), - section_div = c(" "), - indent_mod = 0L - ) %>% - summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) %>% - analyze("CMDECOD", afun = a_freq_j, extra_args = extra_args_1) %>% - append_topleft(" Standardized Medication Name") - -result <- build_table(lyt, cm, alt_counts_df = adsl) + ) + +for (i in seq_along(atcvar)) { + atcvars <- atcvar[[i]] + + lyt <- lyt |> + split_rows_by( + atcvars, + child_labels = "hidden", + split_label = paste0("ATC Level ", i), + label_pos = "topleft", + split_fun = trim_levels_in_group(smnvar), + section_div = c(" "), + indent_mod = 0L + ) |> + summarize_row_groups(atcvars, cfun = a_freq_j, extra_args = extra_args_1) +} + +lyt <- lyt |> + analyze(smnvar, afun = a_freq_j, extra_args = (extra_args_1)) |> + append_topleft(paste(strrep(" ", length(atcvar)), "Standardized Medication Name, n (%)")) + + +result <- build_table(lyt, cm, alt_counts_df = adsl, round_type = "sas") # If there is no data remove top row and display "No data to display" text if (length(adcm$ONTRTFL) == 0) { @@ -181,14 +195,24 @@ if (length(adcm$ONTRTFL) == 0) { ######################################################################################### if (length(adcm$ONTRTFL) != 0) { + path_i <- c("root", atcvar[1]) + + for (i in seq_along(atcvar)) { + if (i == 1) { + path_i <- c("root", atcvar[i]) + } else { + path_i <- c(path_i, "*", atcvar[i]) + } + + result <- sort_at_path( + result, + path_i, + scorefun = jj_complex_scorefun(colpath = "Total") + ) + } result <- sort_at_path( result, - c("root", atcvar), - scorefun = jj_complex_scorefun(colpath = "Total") - ) - result <- sort_at_path( - result, - c("root", atcvar, "*", "CMDECOD"), + c(path_i, "*", smnvar), , scorefun = jj_complex_scorefun(colpath = "Total") ) } @@ -199,9 +223,28 @@ if (length(adcm$ONTRTFL) != 0) { result <- set_titles(result, tab_titles) +# derivation of number of rows column header takes +cps <- col_paths(result)[[1]] +cps <- cps[seq(from = 1, by = 2, length.out = length(cps) / 2)] +### as showcolcounts = TRUE, 1 extra row in columns +levels_cols <- length(cps) + 1 + +bordmat <- junco:::make_header_bordmat(obj = result) +if (levels_cols < length(top_left(result))) { + # Create extra_row(s) based on the difference between top_left length and levels_cols + num_extra_rows <- length(top_left(result)) - levels_cols + for (i in 1:num_extra_rows) { + extra_row <- rep(0, ncol(bordmat)) + bordmat <- rbind(extra_row, bordmat) + } + rownames(bordmat) <- NULL +} + ################################################################################ # Convert to tbl file and output table ################################################################################ + + colwidth <- c(64, 21, 21, 21, 21, 23) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, border_mat = bordmat, orientation = "landscape") diff --git a/tests/testthat/source_code/tsicm02.R b/tests/testthat/source_code/tsicm02.R index 9fe5b886..d9487e6d 100644 --- a/tests/testthat/source_code/tsicm02.R +++ b/tests/testthat/source_code/tsicm02.R @@ -1,33 +1,10 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsicm02.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsicm02: Concomitant Medications by -## ATC Level X/Base Preferred Term - Variant 2 -## Author: Johnson & Johnson Innovative Medicine -## Date: 19 Jan 2024 -## Input: ADSL, ADCM. -## Output: TSICM02.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(tidyr) +library(stringr) ################################################################################ # Define script level parameters: @@ -55,8 +32,9 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" -atcvar <- "CMLVL1" -atclevel <- "1" +smnvar <- "CMBASPRF" +atcvar <- c("CMLVL1", "CMLVL2", "CMLVL3", "CMLVL4") +atclevel <- c("1", "2", "3", "4") combined_colspan_trt <- TRUE @@ -84,28 +62,54 @@ if (combined_colspan_trt == TRUE) { ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(trtvar), all_of(popfl)) -adcm <- adcm_jnj %>% - filter(ONTRTFL == "Y") %>% - select(USUBJID, ONTRTFL, all_of(atcvar), CMBASPRF) - -# Convert medications to sentence case -adcm[[atcvar]] <- as.factor(stringr::str_to_sentence(adcm[[atcvar]])) -adcm$CMBASPRF <- as.factor(stringr::str_to_sentence(adcm$CMBASPRF)) - +adcm <- adcm_jnj |> + filter(ONTRTFL == "Y") |> + select(USUBJID, CMTRT, ONTRTFL, all_of(atcvar), all_of(smnvar)) |> + mutate( + across( + all_of(atcvar), + ~ case_when( + .x == "" ~ "Uncoded", + .default = .x + ) + ), + across( + all_of(atcvar), + ~ str_to_sentence(.x) + ), + !!rlang::sym(smnvar) := case_when( + .data[[smnvar]] == "" ~ paste0("Uncoded: ", CMTRT), + .default = .data[[smnvar]] + ), + across( + all_of(smnvar), + ~ str_to_sentence(.x) + ) + ) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), levels = c("Active Study Agent", " ") ) # join data together -cm <- adcm %>% inner_join(., adsl, by = c("USUBJID")) +cm <- adcm |> inner_join(adsl, by = c("USUBJID")) if (length(adcm$ONTRTFL) == 0) { - cm <- adcm %>% right_join(., adsl, by = c("USUBJID")) + cm <- adcm |> right_join(adsl, by = c("USUBJID")) } colspan_trt_map <- create_colspan_map( @@ -128,22 +132,22 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% - add_overall_col("Total") %>% +lyt <- lyt |> + add_overall_col("Total") |> analyze( "ONTRTFL", afun = a_freq_j, @@ -152,21 +156,29 @@ lyt <- lyt %>% extra_args_1, list(label = "Subjects with >=1 concomitant medication") ) - ) %>% - split_rows_by( - atcvar, - child_labels = "hidden", - split_label = paste0("ATC Level ", atclevel), - label_pos = "topleft", - split_fun = trim_levels_in_group("CMBASPRF"), - section_div = c(" "), - indent_mod = 0L - ) %>% - summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) %>% - analyze("CMBASPRF", afun = a_freq_j, extra_args = (extra_args_1)) %>% - append_topleft(" Base Preferred Term") - -result <- build_table(lyt, cm, alt_counts_df = adsl) + ) + +for (i in seq_along(atcvar)) { + atcvars <- atcvar[[i]] + lyt <- lyt |> + split_rows_by( + atcvars, + child_labels = "hidden", + split_label = paste0("ATC Level ", i), + label_pos = "topleft", + split_fun = trim_levels_in_group(smnvar), + section_div = c(" "), + indent_mod = 0L + ) |> + summarize_row_groups(atcvars, cfun = a_freq_j, extra_args = extra_args_1) +} + +lyt <- lyt |> + analyze(smnvar, afun = a_freq_j, extra_args = (extra_args_1)) |> + append_topleft(paste(strrep(" ", length(atcvar)), "Base Preferred Term, n (%)")) + + +result <- build_table(lyt, cm, alt_counts_df = adsl, round_type = "sas") # If there is no data remove top row and display "No data to display" text if (length(adcm$ONTRTFL) == 0) { @@ -183,14 +195,24 @@ if (length(adcm$ONTRTFL) == 0) { ######################################################################################### if (length(adcm$ONTRTFL) != 0) { + path_i <- c("root", atcvar[1]) + + for (i in seq_along(atcvar)) { + if (i == 1) { + path_i <- c("root", atcvar[i]) + } else { + path_i <- c(path_i, "*", atcvar[i]) + } + + result <- sort_at_path( + result, + path_i, + scorefun = jj_complex_scorefun(colpath = "Total") + ) + } result <- sort_at_path( result, - c("root", atcvar), - scorefun = jj_complex_scorefun(colpath = "Total") - ) - result <- sort_at_path( - result, - c("root", atcvar, "*", "CMBASPRF"), + c(path_i, "*", smnvar), , scorefun = jj_complex_scorefun(colpath = "Total") ) } @@ -201,9 +223,28 @@ if (length(adcm$ONTRTFL) != 0) { result <- set_titles(result, tab_titles) +# derivation of number of rows column header takes +cps <- col_paths(result)[[1]] +cps <- cps[seq(from = 1, by = 2, length.out = length(cps) / 2)] +### as showcolcounts = TRUE, 1 extra row in columns +levels_cols <- length(cps) + 1 + +bordmat <- junco:::make_header_bordmat(obj = result) +if (levels_cols < length(top_left(result))) { + # Create extra_row(s) based on the difference between top_left length and levels_cols + num_extra_rows <- length(top_left(result)) - levels_cols + for (i in 1:num_extra_rows) { + extra_row <- rep(0, ncol(bordmat)) + bordmat <- rbind(extra_row, bordmat) + } + rownames(bordmat) <- NULL +} + ################################################################################ # Convert to tbl file and output table ################################################################################ + + colwidth <- c(64, 21, 21, 21, 21, 23) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, border_mat = bordmat, orientation = "landscape") diff --git a/tests/testthat/source_code/tsicm03.R b/tests/testthat/source_code/tsicm03.R index 905560ab..0940c190 100644 --- a/tests/testthat/source_code/tsicm03.R +++ b/tests/testthat/source_code/tsicm03.R @@ -1,34 +1,10 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsicm03.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsicm03: Concomitant Medications by -## ATC Level X/Standardized Medication Name, with x% -## frequency - Variant 1 -## Author: Johnson & Johnson Innovative Medicine -## Date: 19 Jan 2024 -## Input: ADSL, ADCM. -## Output: TSICM03.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(tidyr) +library(stringr) ################################################################################ # Define script level parameters: @@ -57,10 +33,11 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" -atcvar <- "CMLVL1" -atclevel <- "1" +smnvar <- "CMDECOD" +atcvar <- c("CMLVL1", "CMLVL2", "CMLVL3", "CMLVL4") +atclevel <- c("1", "2", "3", "4") -include_top_row <- FALSE +include_top_row <- TRUE combined_colspan_trt <- TRUE @@ -87,28 +64,54 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(trtvar), all_of(popfl)) -adcm <- adcm_jnj %>% - filter(ONTRTFL == "Y") %>% - select(USUBJID, ONTRTFL, all_of(atcvar), CMDECOD) - -# Convert medications to sentence case -adcm[[atcvar]] <- as.factor(stringr::str_to_sentence(adcm[[atcvar]])) -adcm$CMDECOD <- as.factor(stringr::str_to_sentence(adcm$CMDECOD)) - +adcm <- adcm_jnj |> + filter(ONTRTFL == "Y") |> + select(USUBJID, CMTRT, ONTRTFL, all_of(atcvar), all_of(smnvar)) |> + mutate( + across( + all_of(atcvar), + ~ case_when( + .x == "" ~ "Uncoded", + .default = .x + ) + ), + across( + all_of(atcvar), + ~ str_to_sentence(.x) + ), + !!rlang::sym(smnvar) := case_when( + .data[[smnvar]] == "" ~ paste0("Uncoded: ", CMTRT), + .default = .data[[smnvar]] + ), + across( + all_of(smnvar), + ~ str_to_sentence(.x) + ) + ) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), levels = c("Active Study Agent", " ") ) # join data together -cm <- adcm %>% inner_join(., adsl, by = c("USUBJID")) +cm <- adcm |> inner_join(adsl, by = c("USUBJID")) if (length(adcm$ONTRTFL) == 0) { - cm <- adcm %>% right_join(., adsl, by = c("USUBJID")) + cm <- adcm |> right_join(adsl, by = c("USUBJID")) } colspan_trt_map <- create_colspan_map( @@ -130,25 +133,25 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> add_overall_col("Total") if (include_top_row == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> analyze( "ONTRTFL", afun = a_freq_j, @@ -160,36 +163,51 @@ if (include_top_row == TRUE) { ) } -lyt <- lyt %>% - split_rows_by( - atcvar, - child_labels = "hidden", - split_label = paste0("ATC Level ", atclevel), - label_pos = "topleft", - split_fun = trim_levels_in_group("CMDECOD"), - section_div = c(" "), - indent_mod = 0L - ) %>% - summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) %>% - summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) %>% - analyze("CMDECOD", afun = a_freq_j, extra_args = (extra_args_1)) %>% - append_topleft(" Standardized Medication Name") - -result <- build_table(lyt, cm, alt_counts_df = adsl) +for (i in seq_along(atcvar)) { + atcvars <- atcvar[[i]] + + lyt <- lyt |> + split_rows_by( + atcvars, + child_labels = "hidden", + split_label = paste0("ATC Level ", i), + label_pos = "topleft", + split_fun = trim_levels_in_group(smnvar), + section_div = c(" "), + indent_mod = 0L + ) |> + summarize_row_groups(atcvars, cfun = a_freq_j, extra_args = extra_args_1) +} + +lyt <- lyt |> + analyze(smnvar, afun = a_freq_j, extra_args = (extra_args_1)) |> + append_topleft(paste(strrep(" ", length(atcvar)), "Standardized Medication Name, n (%)")) + +result <- build_table(lyt, cm, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on total column: ######################################################################################### if (length(adcm$ONTRTFL) != 0) { + path_i <- c("root", atcvar[1]) + + for (i in seq_along(atcvar)) { + if (i == 1) { + path_i <- c("root", atcvar[i]) + } else { + path_i <- c(path_i, "*", atcvar[i]) + } + + result <- sort_at_path( + result, + path_i, + scorefun = jj_complex_scorefun(colpath = "Total") + ) + } result <- sort_at_path( result, - c("root", atcvar), - scorefun = jj_complex_scorefun(colpath = "Total") - ) - result <- sort_at_path( - result, - c("root", atcvar, "*", "CMDECOD"), + c(path_i, "*", smnvar), , scorefun = jj_complex_scorefun(colpath = "Total") ) @@ -222,9 +240,27 @@ if (length(adcm$ONTRTFL) == 0) { result <- set_titles(result, tab_titles) +# derivation of number of rows column header takes +cps <- col_paths(result)[[1]] +cps <- cps[seq(from = 1, by = 2, length.out = length(cps) / 2)] +### as showcolcounts = TRUE, 1 extra row in columns +levels_cols <- length(cps) + 1 + +bordmat <- junco:::make_header_bordmat(obj = result) +if (levels_cols < length(top_left(result))) { + # Create extra_row(s) based on the difference between top_left length and levels_cols + num_extra_rows <- length(top_left(result)) - levels_cols + for (i in 1:num_extra_rows) { + extra_row <- rep(0, ncol(bordmat)) + bordmat <- rbind(extra_row, bordmat) + } + rownames(bordmat) <- NULL +} + ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(62, 21, 21, 21, 21, 23) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(64, 21, 21, 21, 21, 23) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, border_mat = bordmat, orientation = "landscape") diff --git a/tests/testthat/source_code/tsicm04.R b/tests/testthat/source_code/tsicm04.R index c6c10762..6836f676 100644 --- a/tests/testthat/source_code/tsicm04.R +++ b/tests/testthat/source_code/tsicm04.R @@ -1,34 +1,10 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsicm04.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsicm04: Concomitant Medications by -## ATC Level X/Base Preferred Term, with x% frequency - -## Variant 2 -## Author: Johnson & Johnson Innovative Medicine -## Date: 19 Jan 2024 -## Input: ADSL, ADCM. -## Output: TSICM04.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) library(rtables) library(junco) +library(tidyr) +library(stringr) ################################################################################ # Define script level parameters: @@ -57,10 +33,11 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" -atcvar <- "CMLVL1" -atclevel <- "1" +smnvar <- "CMBASPRF" +atcvar <- c("CMLVL1", "CMLVL2", "CMLVL3", "CMLVL4") +atclevel <- c("1", "2", "3", "4") -include_top_row <- FALSE +include_top_row <- TRUE combined_colspan_trt <- TRUE @@ -87,17 +64,44 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(trtvar), all_of(popfl)) -adcm <- adcm_jnj %>% - filter(ONTRTFL == "Y") %>% - select(USUBJID, ONTRTFL, all_of(atcvar), CMBASPRF) - -# Convert medications to sentence case -adcm[[atcvar]] <- as.factor(stringr::str_to_sentence(adcm[[atcvar]])) -adcm$CMBASPRF <- as.factor(stringr::str_to_sentence(adcm$CMBASPRF)) +adcm <- adcm_jnj |> + filter(ONTRTFL == "Y") |> + select(USUBJID, CMTRT, ONTRTFL, all_of(atcvar), all_of(smnvar)) |> + mutate( + across( + all_of(atcvar), + ~ case_when( + .x == "" ~ "Uncoded", + .default = .x + ) + ), + across( + all_of(atcvar), + ~ str_to_sentence(.x) + ), + !!rlang::sym(smnvar) := case_when( + .data[[smnvar]] == "" ~ paste0("Uncoded: ", CMTRT), + .default = .data[[smnvar]] + ), + across( + all_of(smnvar), + ~ str_to_sentence(.x) + ) + ) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -105,10 +109,10 @@ adsl$colspan_trt <- factor( ) # join data together -cm <- adcm %>% inner_join(., adsl, by = c("USUBJID")) +cm <- adcm |> inner_join(adsl, by = c("USUBJID")) if (length(adcm$ONTRTFL) == 0) { - cm <- adcm %>% right_join(., adsl, by = c("USUBJID")) + cm <- adcm |> right_join(adsl, by = c("USUBJID")) } colspan_trt_map <- create_colspan_map( @@ -130,25 +134,25 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> add_overall_col("Total") if (include_top_row == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> analyze( "ONTRTFL", afun = a_freq_j, @@ -159,35 +163,51 @@ if (include_top_row == TRUE) { ) } -lyt <- lyt %>% - split_rows_by( - atcvar, - child_labels = "hidden", - split_label = paste0("ATC Level ", atclevel), - label_pos = "topleft", - split_fun = trim_levels_in_group("CMBASPRF"), - section_div = c(" "), - indent_mod = 0L - ) %>% - summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) %>% - analyze("CMBASPRF", afun = a_freq_j, extra_args = (extra_args_1)) %>% - append_topleft(" Base Preferred Term") - -result <- build_table(lyt, cm, alt_counts_df = adsl) +for (i in seq_along(atcvar)) { + atcvars <- atcvar[[i]] + + lyt <- lyt |> + split_rows_by( + atcvars, + child_labels = "hidden", + split_label = paste0("ATC Level ", i), + label_pos = "topleft", + split_fun = trim_levels_in_group(smnvar), + section_div = c(" "), + indent_mod = 0L + ) |> + summarize_row_groups(atcvars, cfun = a_freq_j, extra_args = extra_args_1) +} + +lyt <- lyt |> + analyze(smnvar, afun = a_freq_j, extra_args = (extra_args_1)) |> + append_topleft(paste(strrep(" ", length(atcvar)), "Base Preferred Term, n (%)")) + +result <- build_table(lyt, cm, alt_counts_df = adsl, round_type = "sas") ######################################################################################### # Post-Processing step to sort by descending count on total column: ######################################################################################### if (length(adcm$ONTRTFL) != 0) { + path_i <- c("root", atcvar[1]) + + for (i in seq_along(atcvar)) { + if (i == 1) { + path_i <- c("root", atcvar[i]) + } else { + path_i <- c(path_i, "*", atcvar[i]) + } + + result <- sort_at_path( + result, + path_i, + scorefun = jj_complex_scorefun(colpath = "Total") + ) + } result <- sort_at_path( result, - c("root", atcvar), - scorefun = jj_complex_scorefun(colpath = "Total") - ) - result <- sort_at_path( - result, - c("root", atcvar, "*", "CMBASPRF"), + c(path_i, "*", smnvar), , scorefun = jj_complex_scorefun(colpath = "Total") ) @@ -220,9 +240,29 @@ if (length(adcm$ONTRTFL) == 0) { result <- set_titles(result, tab_titles) + +# derivation of number of rows column header takes +cps <- col_paths(result)[[1]] +cps <- cps[seq(from = 1, by = 2, length.out = length(cps) / 2)] +### as showcolcounts = TRUE, 1 extra row in columns +levels_cols <- length(cps) + 1 + +bordmat <- junco:::make_header_bordmat(obj = result) +if (levels_cols < length(top_left(result))) { + # Create extra_row(s) based on the difference between top_left length and levels_cols + num_extra_rows <- length(top_left(result)) - levels_cols + for (i in 1:num_extra_rows) { + extra_row <- rep(0, ncol(bordmat)) + bordmat <- rbind(extra_row, bordmat) + } + rownames(bordmat) <- NULL +} + ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(62, 21, 21, 21, 21, 23) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") + +colwidth <- c(64, 21, 21, 21, 21, 23) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, border_mat = bordmat, orientation = "landscape") diff --git a/tests/testthat/source_code/tsicm05.R b/tests/testthat/source_code/tsicm05.R index 050e4f07..e4c0b860 100644 --- a/tests/testthat/source_code/tsicm05.R +++ b/tests/testthat/source_code/tsicm05.R @@ -1,31 +1,7 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsicm05.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsicm05: Prior Medications by ATC -## Level X/Standardized Medication Name - Variant 1 -## Author: Johnson & Johnson Innovative Medicine -## Date: 13 Nov 2023 -## Input: ADSL, ADCM. -## Output: TSICM05.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) +library(tidyr) library(rtables) library(junco) @@ -37,8 +13,9 @@ library(junco) # - Define output ID and file location # - Define treatment variable used (default=TRT01A) # - Define population flag used (default=SAFFL) -# - Define dynamic ATC variable -# - Define dynamic ATC Level +# - Define substitution flag for concomitant medications (default=PREFL) +# - Define Standardized Medication variable(default=CMDECOD) +# - Define ATC variables # - Choose whether or not you want to present a combined active treatment column (default=TRUE) # - Define how to create combined treatment columns (if required) ################################################################################ @@ -54,9 +31,10 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" +substfl <- "PREFL" -atcvar <- "CMLVL1" -atclevel <- "1" +smnvar <- "CMDECOD" +atcvars <- c("CMLVL1", "CMLVL2", "CMLVL3", "CMLVL4") combined_colspan_trt <- TRUE @@ -83,17 +61,44 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(trtvar), all_of(popfl)) -adcm <- adcm_jnj %>% - filter(PREFL == "Y") %>% - select(USUBJID, PREFL, all_of(atcvar), CMDECOD) - -# Convert medications to sentence case -adcm[[atcvar]] <- as.factor(stringr::str_to_sentence(adcm[[atcvar]])) -adcm$CMDECOD <- as.factor(stringr::str_to_sentence(adcm$CMDECOD)) +adcm <- adcm_jnj |> + filter(!!rlang::sym(substfl) == "Y") |> + select(USUBJID, all_of(substfl), all_of(atcvars), all_of(smnvar), CMTRT) |> + mutate( + across( + all_of(atcvars), + ~ case_when( + .x == "" ~ "Uncoded", + .default = .x + ) + ), + across( + all_of(atcvars), + ~ as.factor(stringr::str_to_sentence(.x)) + ), + !!rlang::sym(smnvar) := case_when( + .data[[smnvar]] == "" ~ paste0("Uncoded: ", CMTRT), + .default = .data[[smnvar]] + ), + across( + all_of(smnvar), + ~ as.factor(stringr::str_to_sentence(.x)) + ) + ) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -101,10 +106,10 @@ adsl$colspan_trt <- factor( ) # join data together -cm <- adcm %>% inner_join(., adsl, by = c("USUBJID")) +cm <- adcm |> inner_join(adsl, by = c("USUBJID")) -if (length(adcm$PREFL) == 0) { - cm <- adcm %>% right_join(., adsl, by = c("USUBJID")) +if (length(adcm[[substfl]]) == 0) { + cm <- adcm |> right_join(adsl, by = c("USUBJID")) } colspan_trt_map <- create_colspan_map( @@ -122,52 +127,59 @@ colspan_trt_map <- create_colspan_map( extra_args_1 <- list(.stats = "count_unique_fraction") - lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% - add_overall_col("Total") %>% +lyt <- lyt |> + add_overall_col("Total") |> analyze( - "PREFL", + substfl, afun = a_freq_j, extra_args = append( extra_args_1, list(label = "Subjects with >=1 prior medication") ) - ) %>% - split_rows_by( - atcvar, - child_labels = "hidden", - split_label = paste0("ATC Level ", atclevel), - label_pos = "topleft", - split_fun = trim_levels_in_group("CMDECOD"), - section_div = c(" "), - indent_mod = 0L - ) %>% - summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) %>% - analyze("CMDECOD", afun = a_freq_j, extra_args = (extra_args_1)) %>% - append_topleft(" Standardized Medication Name") - -result <- build_table(lyt, cm, alt_counts_df = adsl) + ) + +for (i in seq_along(atcvars)) { + atcvar <- atcvars[[i]] + + lyt <- lyt |> + split_rows_by( + atcvar, + child_labels = "hidden", + split_label = paste0("ATC Level ", sub(".*([0-9]{1,2})$", "\\1", atcvar)), + label_pos = "topleft", + split_fun = trim_levels_in_group(smnvar), + section_div = c(" "), + indent_mod = 0L + ) |> + summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) +} + +lyt <- lyt |> + analyze(smnvar, afun = a_freq_j, extra_args = (extra_args_1)) |> + append_topleft(paste(strrep(" ", length(atcvars) - 1), " Standardized Medication Name, n (%)")) + +result <- build_table(lyt, cm, alt_counts_df = adsl, round_type = "sas") # If there is no data remove top row and display "No data to display" text -if (length(adcm$PREFL) == 0) { +if (length(adcm[[substfl]]) == 0) { result <- safe_prune_table( result, prune_func = remove_rows( @@ -180,17 +192,23 @@ if (length(adcm$PREFL) == 0) { # Post-Processing step to sort by descending count on total column: ######################################################################################### -if (length(adcm$PREFL) != 0) { - result <- sort_at_path( - result, - c("root", atcvar), - scorefun = jj_complex_scorefun(colpath = "Total") - ) - result <- sort_at_path( - result, - c("root", atcvar, "*", "CMDECOD"), - scorefun = jj_complex_scorefun(colpath = "Total") - ) +if (length(adcm[[substfl]]) != 0) { + for (i in seq_along(atcvars)) { + atcvar <- atcvars[[1]] + paths <- unlist(lapply(seq_along(atcvars), function(i) c(atcvars[[i]], "*"))) + + result <- sort_at_path( + result, + c("root", atcvar), + scorefun = jj_complex_scorefun(colpath = "Total") + ) + + result <- sort_at_path( + result, + c("root", paths, smnvar), + scorefun = jj_complex_scorefun(colpath = "Total") + ) + } } ################################################################################ @@ -199,9 +217,26 @@ if (length(adcm$PREFL) != 0) { result <- set_titles(result, tab_titles) +# derivation of number of rows column header takes +cps <- col_paths(result)[[1]] +cps <- cps[seq(from = 1, by = 2, length.out = length(cps) / 2)] +### as showcolcounts = TRUE, 1 extra row in columns +levels_cols <- length(cps) + 1 + +bordmat <- junco:::make_header_bordmat(obj = result) +if (levels_cols < length(top_left(result))) { + # Create extra_row(s) based on the difference between top_left length and levels_cols + num_extra_rows <- length(top_left(result)) - levels_cols + for (i in 1:num_extra_rows) { + extra_row <- rep(0, ncol(bordmat)) + bordmat <- rbind(extra_row, bordmat) + } + rownames(bordmat) <- NULL +} ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(57, 21, 21, 21, 21, 23) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(63, 21, 21, 21, 21, 23) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, border_mat = bordmat, label_width_ins = 2.4, orientation = "landscape") diff --git a/tests/testthat/source_code/tsicm06.R b/tests/testthat/source_code/tsicm06.R index 004a0ab6..5b181b83 100644 --- a/tests/testthat/source_code/tsicm06.R +++ b/tests/testthat/source_code/tsicm06.R @@ -1,28 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsicm06.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsicm06: Prior Medications by ATC -## Level X/Base Preferred Term - Variant 2 -## Author: Johnson & Johnson Innovative Medicine -## Date: 19 Jan 2024 -## Input: ADSL, ADCM. -## Output: TSICM06.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -37,8 +12,9 @@ library(junco) # - Define output ID and file location # - Define treatment variable used (default=TRT01A) # - Define population flag used (default=SAFFL) -# - Define dynamic ATC variable -# - Define dynamic ATC Level +# - Define substitution flag for concomitant medications (default=PREFL) +# - Define standard mediation variable (default=CMBASPRF) +# - Define ATC variables # - Choose whether or not you want to present a combined active treatment column (default=TRUE) # - Define how to create combined treatment columns (if required) ################################################################################ @@ -54,9 +30,10 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" +substfl <- "PREFL" -atcvar <- "CMLVL1" -atclevel <- "1" +smnvar <- "CMBASPRF" +atcvars <- c("CMLVL1", "CMLVL2", "CMLVL3", "CMLVL4") combined_colspan_trt <- TRUE @@ -83,17 +60,44 @@ if (combined_colspan_trt == TRUE) { # Process Data: ################################################################################ -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(trtvar), all_of(popfl)) -adcm <- adcm_jnj %>% - filter(PREFL == "Y") %>% - select(USUBJID, PREFL, all_of(atcvar), CMBASPRF) - -# Convert medications to sentence case -adcm[[atcvar]] <- as.factor(stringr::str_to_sentence(adcm[[atcvar]])) -adcm$CMBASPRF <- as.factor(stringr::str_to_sentence(adcm$CMBASPRF)) +adcm <- adcm_jnj |> + filter(!!rlang::sym(substfl) == "Y") |> + select(USUBJID, all_of(substfl), all_of(atcvars), all_of(smnvar), CMTRT) |> + mutate( + across( + all_of(atcvars), + ~ case_when( + .x == "" ~ "Uncoded", + .default = .x + ) + ), + across( + all_of(atcvars), + ~ as.factor(stringr::str_to_sentence(.x)) + ), + !!rlang::sym(smnvar) := case_when( + .data[[smnvar]] == "" ~ paste0("Uncoded: ", CMTRT), + .default = .data[[smnvar]] + ), + across( + all_of(smnvar), + ~ as.factor(stringr::str_to_sentence(.x)) + ) + ) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -101,10 +105,10 @@ adsl$colspan_trt <- factor( ) # join data together -cm <- adcm %>% inner_join(., adsl, by = c("USUBJID")) +cm <- adcm |> inner_join(adsl, by = c("USUBJID")) -if (length(adcm$PREFL) == 0) { - cm <- adcm %>% right_join(., adsl, by = c("USUBJID")) +if (length(adcm[[substfl]]) == 0) { + cm <- adcm |> right_join(adsl, by = c("USUBJID")) } colspan_trt_map <- create_colspan_map( @@ -126,47 +130,55 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% - add_overall_col("Total") %>% +lyt <- lyt |> + add_overall_col("Total") |> analyze( - "PREFL", + substfl, afun = a_freq_j, extra_args = append( extra_args_1, list(label = "Subjects with >=1 prior medication") ) - ) %>% - split_rows_by( - atcvar, - child_labels = "hidden", - split_label = paste0("ATC Level ", atclevel), - label_pos = "topleft", - split_fun = trim_levels_in_group("CMBASPRF"), - section_div = c(" "), - indent_mod = 0L - ) %>% - summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) %>% - analyze("CMBASPRF", afun = a_freq_j, extra_args = (extra_args_1)) %>% - append_topleft(" Base Preferred Term") - -result <- build_table(lyt, cm, alt_counts_df = adsl) + ) + +for (i in seq_along(atcvars)) { + atcvar <- atcvars[[i]] + + lyt <- lyt |> + split_rows_by( + atcvar, + child_labels = "hidden", + split_label = paste0("ATC Level ", sub(".*([0-9]{1,2})$", "\\1", atcvar)), + label_pos = "topleft", + split_fun = trim_levels_in_group(smnvar), + section_div = c(" "), + indent_mod = 0L + ) |> + summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) +} + +lyt <- lyt |> + analyze(smnvar, afun = a_freq_j, extra_args = (extra_args_1)) |> + append_topleft(paste(strrep(" ", length(atcvars) - 1), " Base Preferred Term, n (%)")) + +result <- build_table(lyt, cm, alt_counts_df = adsl, round_type = "sas") # If there is no data remove top row and display "No data to display" text -if (length(adcm$PREFL) == 0) { +if (length(adcm[[substfl]]) == 0) { result <- safe_prune_table( result, prune_func = remove_rows( @@ -179,17 +191,22 @@ if (length(adcm$PREFL) == 0) { # Post-Processing step to sort by descending count on total column: ######################################################################################### -if (length(adcm$PREFL) != 0) { - result <- sort_at_path( - result, - c("root", atcvar), - scorefun = jj_complex_scorefun(colpath = "Total") - ) - result <- sort_at_path( - result, - c("root", atcvar, "*", "CMBASPRF"), - scorefun = jj_complex_scorefun(colpath = "Total") - ) +if (length(adcm[[substfl]]) != 0) { + for (i in seq_along(atcvars)) { + atcvar <- atcvars[[1]] + paths <- unlist(lapply(seq_along(atcvars), function(i) c(atcvars[[i]], "*"))) + + result <- sort_at_path( + result, + c("root", atcvar), + scorefun = jj_complex_scorefun(colpath = "Total") + ) + result <- sort_at_path( + result, + c("root", paths, smnvar), + scorefun = jj_complex_scorefun(colpath = "Total") + ) + } } ################################################################################ @@ -198,9 +215,27 @@ if (length(adcm$PREFL) != 0) { result <- set_titles(result, tab_titles) +# derivation of number of rows column header takes +cps <- col_paths(result)[[1]] +cps <- cps[seq(from = 1, by = 2, length.out = length(cps) / 2)] +### as showcolcounts = TRUE, 1 extra row in columns +levels_cols <- length(cps) + 1 + +bordmat <- junco:::make_header_bordmat(obj = result) +if (levels_cols < length(top_left(result))) { + # Create extra_row(s) based on the difference between top_left length and levels_cols + num_extra_rows <- length(top_left(result)) - levels_cols + for (i in 1:num_extra_rows) { + extra_row <- rep(0, ncol(bordmat)) + bordmat <- rbind(extra_row, bordmat) + } + rownames(bordmat) <- NULL +} + ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(57, 21, 21, 21, 21, 23) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(63, 21, 21, 21, 21, 23) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, border_mat = bordmat, label_width_ins = 2.4, orientation = "landscape") diff --git a/tests/testthat/source_code/tsicm07.R b/tests/testthat/source_code/tsicm07.R index 33deb9b5..f477243e 100644 --- a/tests/testthat/source_code/tsicm07.R +++ b/tests/testthat/source_code/tsicm07.R @@ -1,28 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsicm07.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsicm07: Concomitant Medications of -## Interest - Variant 1 (Standardized Medication Name) -## Author: Johnson & Johnson Innovative Medicine -## Date: 14 Dec 2023 -## Input: ADSL, ADCM. -## Output: TSICM07.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -37,7 +12,9 @@ library(junco) # - Define output ID and file location # - Define treatment variable used (default=TRT01A) # - Define population flag used (default=SAFFL) -# - Define dynamic coded term variable +# - Define substitution flag for concomitant medications (default=ONTRTFL) +# - Define ATC variables +# - Define coded term variable (default=CMDECOD) # - Choose whether or not you want to present a combined active treatment column (default=TRUE) # - Define how to create combined treatment columns (if required) ################################################################################ @@ -53,7 +30,9 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" +substfl <- "ONTRTFL" +atcvars <- c("CMLVL1", "CMLVL2", "CMLVL3", "CMLVL4") codedtermvar <- "CMDECOD" combined_colspan_trt <- TRUE @@ -82,18 +61,55 @@ if (combined_colspan_trt == TRUE) { ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(trtvar), all_of(popfl)) -adcm <- adcm_jnj %>% - filter(ONTRTFL == "Y") %>% - select(USUBJID, ONTRTFL, all_of(codedtermvar), starts_with("CQ")) %>% - select(USUBJID, ONTRTFL, all_of(codedtermvar), ends_with("NAM")) +adcm <- adcm_jnj |> + filter(!!rlang::sym(substfl) == "Y") |> + select( + USUBJID, + all_of(substfl), + all_of(codedtermvar), + starts_with("CQ") & ends_with("NAM"), + starts_with("CMLVL"), + CMTRT + ) |> + mutate( + across( + all_of(atcvars), + ~ case_when( + .x == "" ~ "Uncoded", + .default = .x + ) + ), + across( + all_of(atcvars), + ~ as.factor(stringr::str_to_sentence(.x)) + ), + !!rlang::sym(codedtermvar) := case_when( + .data[[codedtermvar]] == "" ~ paste0("Uncoded: ", CMTRT), + .default = .data[[codedtermvar]] + ), + across( + all_of(codedtermvar), + ~ as.factor(stringr::str_to_sentence(.x)) + ) + ) # Work out how many CQzzNAM vars we have -cqzznamvars <- adcm %>% - select(starts_with("CQ")) +cqzznamvars <- adcm |> + select(starts_with("CQ") & ends_with("NAM")) countcqzznamvars <- length(names(cqzznamvars)) @@ -108,28 +124,23 @@ for (i in 1:countcqzznamvars) { ix <- i } - cqdata <- adcm %>% - mutate(cqnamvar = as.factor(!!as.name(paste0("CQ", ix, "NAM")))) %>% + cqdata <- adcm |> + mutate(cqnamvar = as.factor(!!as.name(paste0("CQ", ix, "NAM")))) |> filter(!is.na(cqnamvar)) adcm_v <- bind_rows(adcm_v, cqdata) } -# Convert medications to sentence case -adcm_v[[codedtermvar]] <- as.factor(stringr::str_to_sentence(adcm_v[[ - codedtermvar -]])) - adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), levels = c("Active Study Agent", " ") ) # join data together -cm <- adcm_v %>% inner_join(., adsl, by = c("USUBJID")) +cm <- adcm_v |> inner_join(adsl, by = c("USUBJID")) -if (length(adcm$ONTRTFL) == 0) { - cm <- adcm_v %>% right_join(., adsl, by = c("USUBJID")) +if (length(adcm[[substfl]]) == 0) { + cm <- adcm_v |> right_join(adsl, by = c("USUBJID")) } colspan_trt_map <- create_colspan_map( @@ -151,36 +162,24 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> add_overall_col("Total") -if (length(adcm$ONTRTFL) == 0) { - lyt <- lyt %>% - analyze( - "ONTRTFL", - afun = a_freq_j, - extra_args = append( - extra_args_1, - list(label = "Subjects with >=1 concomitant medication") - ) - ) -} - -lyt <- lyt %>% +lyt <- lyt |> split_rows_by( "cqnamvar", child_labels = "hidden", @@ -189,42 +188,55 @@ lyt <- lyt %>% split_fun = trim_levels_in_group(codedtermvar), section_div = c(" "), indent_mod = 0L - ) %>% + ) |> summarize_row_groups( "cqnamvar", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% - analyze(codedtermvar, afun = a_freq_j, extra_args = (extra_args_1)) %>% - append_topleft(" Standardized Medication Name") - -result <- build_table(lyt, cm, alt_counts_df = adsl) - -# If there is no data remove top row and display "No data to display" text -if (length(adcm$ONTRTFL) == 0) { - result <- safe_prune_table( - result, - prune_func = remove_rows( - removerowtext = "Subjects with >=1 concomitant medication" - ) ) + +for (i in seq_along(atcvars)) { + atcvar <- atcvars[[i]] + + lyt <- lyt |> + split_rows_by( + atcvar, + child_labels = "hidden", + split_label = paste0("ATC Level ", sub(".*([0-9]{1,2})$", "\\1", atcvar)), + label_pos = "topleft", + split_fun = trim_levels_in_group(codedtermvar), + section_div = c(" "), + indent_mod = 0L + ) |> + summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) } +lyt <- lyt |> + analyze(codedtermvar, afun = a_freq_j, extra_args = (extra_args_1)) |> + append_topleft(paste(strrep(" ", length(atcvars)), " Standardized Medication Name, n (%)")) + +result <- build_table(lyt, cm, alt_counts_df = adsl, round_type = "sas") + ######################################################################################### # Post-Processing step to sort by descending count on total column ######################################################################################### -if (length(adcm$ONTRTFL) != 0) { +if (length(adcm[[substfl]]) != 0) { result <- sort_at_path( result, c("cqnamvar"), scorefun = jj_complex_scorefun(colpath = "Total") ) - result <- sort_at_path( - result, - c("cqnamvar", "*", codedtermvar), - scorefun = jj_complex_scorefun(colpath = "Total") - ) + + for (i in seq_along(atcvars)) { + paths <- unlist(lapply(seq_along(atcvars), function(i) c(atcvars[[i]], "*"))) + + result <- sort_at_path( + result, + c("cqnamvar", "*", paths, codedtermvar), + scorefun = jj_complex_scorefun(colpath = "Total") + ) + } } ################################################################################ @@ -233,9 +245,27 @@ if (length(adcm$ONTRTFL) != 0) { result <- set_titles(result, tab_titles) +# derivation of number of rows column header takes +cps <- col_paths(result)[[1]] +cps <- cps[seq(from = 1, by = 2, length.out = length(cps) / 2)] +### as showcolcounts = TRUE, 1 extra row in columns +levels_cols <- length(cps) + 1 + +bordmat <- junco:::make_header_bordmat(obj = result) +if (levels_cols < length(top_left(result))) { + # Create extra_row(s) based on the difference between top_left length and levels_cols + num_extra_rows <- length(top_left(result)) - levels_cols + for (i in 1:num_extra_rows) { + extra_row <- rep(0, ncol(bordmat)) + bordmat <- rbind(extra_row, bordmat) + } + rownames(bordmat) <- NULL +} + ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(34, 19, 19, 21, 17, 19) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(64, 19, 17, 21, 17, 19) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, border_mat = bordmat, label_width_ins = 2.4, orientation = "landscape") diff --git a/tests/testthat/source_code/tsicm08.R b/tests/testthat/source_code/tsicm08.R index 0c4b3190..9cf49f9a 100644 --- a/tests/testthat/source_code/tsicm08.R +++ b/tests/testthat/source_code/tsicm08.R @@ -1,28 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsicm08.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsicm08: Concomitant Medications of -## Interest - Variant 2 (Base Preferred Term) -## Author: Johnson & Johnson Innovative Medicine -## Date: 19 Jan 2024 -## Input: ADSL, ADCM. -## Output: TSICM08.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -37,6 +12,8 @@ library(junco) # - Define output ID and file location # - Define treatment variable used (default=TRT01A) # - Define population flag used (default=SAFFL) +# - Define substitution flag for concomitant medications (default=ONTRTFL) +# - Define ATC variables # - Define dynamic coded term variable # - Choose whether or not you want to present a combined active treatment column (default=TRUE) # - Define how to create combined treatment columns (if required) @@ -52,7 +29,9 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" +substfl <- "ONTRTFL" +atcvars <- c("CMLVL1", "CMLVL2", "CMLVL3", "CMLVL4") codedtermvar <- "CMBASPRF" combined_colspan_trt <- TRUE @@ -81,18 +60,55 @@ if (combined_colspan_trt == TRUE) { ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(trtvar), all_of(popfl)) -adcm <- adcm_jnj %>% - filter(ONTRTFL == "Y") %>% - select(USUBJID, ONTRTFL, all_of(codedtermvar), starts_with("CQ")) %>% - select(USUBJID, ONTRTFL, all_of(codedtermvar), ends_with("NAM")) +adcm <- adcm_jnj |> + filter(!!rlang::sym(substfl) == "Y") |> + select( + USUBJID, + all_of(substfl), + all_of(codedtermvar), + starts_with("CQ") & ends_with("NAM"), + starts_with("CMLVL"), + CMTRT + ) |> + mutate( + across( + all_of(atcvars), + ~ case_when( + .x == "" ~ "Uncoded", + .default = .x + ) + ), + across( + all_of(atcvars), + ~ as.factor(stringr::str_to_sentence(.x)) + ), + !!rlang::sym(codedtermvar) := case_when( + .data[[codedtermvar]] == "" ~ paste0("Uncoded: ", CMTRT), + .default = .data[[codedtermvar]] + ), + across( + all_of(codedtermvar), + ~ as.factor(stringr::str_to_sentence(.x)) + ) + ) # Work out how many CQzzNAM vars we have -cqzznamvars <- adcm %>% - select(starts_with("CQ")) +cqzznamvars <- adcm |> + select(starts_with("CQ") & ends_with("NAM")) countcqzznamvars <- length(names(cqzznamvars)) @@ -107,28 +123,23 @@ for (i in 1:countcqzznamvars) { ix <- i } - cqdata <- adcm %>% - mutate(cqnamvar = as.factor(!!as.name(paste0("CQ", ix, "NAM")))) %>% + cqdata <- adcm |> + mutate(cqnamvar = as.factor(!!as.name(paste0("CQ", ix, "NAM")))) |> filter(!is.na(cqnamvar)) adcm_v <- bind_rows(adcm_v, cqdata) } -# Convert medications to sentence case -adcm_v[[codedtermvar]] <- as.factor(stringr::str_to_sentence(adcm_v[[ - codedtermvar -]])) - adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), levels = c("Active Study Agent", " ") ) # join data together -cm <- adcm_v %>% inner_join(., adsl, by = c("USUBJID")) +cm <- adcm_v |> inner_join(adsl, by = c("USUBJID")) -if (length(adcm$ONTRTFL) == 0) { - cm <- adcm_v %>% right_join(., adsl, by = c("USUBJID")) +if (length(adcm[[substfl]]) == 0) { + cm <- adcm_v |> right_join(adsl, by = c("USUBJID")) } colspan_trt_map <- create_colspan_map( @@ -153,36 +164,24 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> add_overall_col("Total") -if (length(adcm$ONTRTFL) == 0) { - lyt <- lyt %>% - analyze( - "ONTRTFL", - afun = a_freq_j, - extra_args = append( - extra_args_1, - list(label = "Subjects with >=1 concomitant medication") - ) - ) -} - -lyt <- lyt %>% +lyt <- lyt |> split_rows_by( "cqnamvar", child_labels = "hidden", @@ -191,42 +190,54 @@ lyt <- lyt %>% split_fun = trim_levels_in_group(codedtermvar), section_div = c(" "), indent_mod = 0L - ) %>% + ) |> summarize_row_groups( "cqnamvar", cfun = a_freq_j, extra_args = extra_args_1 - ) %>% - analyze(codedtermvar, afun = a_freq_j, extra_args = (extra_args_1)) %>% - append_topleft(" Base Preferred Term") - -result <- build_table(lyt, cm, alt_counts_df = adsl) - -# If there is no data remove top row and display "No data to display" text -if (length(adcm$ONTRTFL) == 0) { - result <- safe_prune_table( - result, - prune_func = remove_rows( - removerowtext = "Subjects with >=1 concomitant medication" - ) ) + +for (i in seq_along(atcvars)) { + atcvar <- atcvars[[i]] + + lyt <- lyt |> + split_rows_by( + atcvar, + child_labels = "hidden", + split_label = paste0("ATC Level ", sub(".*([0-9]{1,2})$", "\\1", atcvar)), + label_pos = "topleft", + split_fun = trim_levels_in_group(codedtermvar), + section_div = c(" "), + indent_mod = 0L + ) |> + summarize_row_groups(atcvar, cfun = a_freq_j, extra_args = extra_args_1) } +lyt <- lyt |> + analyze(codedtermvar, afun = a_freq_j, extra_args = (extra_args_1)) |> + append_topleft(paste(strrep(" ", length(atcvars)), " Base Preferred Term, n (%)")) + +result <- build_table(lyt, cm, alt_counts_df = adsl, round_type = "sas") + ######################################################################################### # Post-Processing step to sort by descending count on total column ######################################################################################### -if (length(adcm$ONTRTFL) != 0) { +if (length(adcm[[substfl]]) != 0) { result <- sort_at_path( result, c("cqnamvar"), scorefun = jj_complex_scorefun(colpath = "Total") ) - result <- sort_at_path( - result, - c("cqnamvar", "*", codedtermvar), - scorefun = jj_complex_scorefun(colpath = "Total") - ) + + for (i in seq_along(atcvars)) { + paths <- unlist(lapply(seq_along(atcvars), function(i) c(atcvars[[i]], "*"))) + result <- sort_at_path( + result, + c("cqnamvar", "*", paths, codedtermvar), + scorefun = jj_complex_scorefun(colpath = "Total") + ) + } } ################################################################################ @@ -235,9 +246,27 @@ if (length(adcm$ONTRTFL) != 0) { result <- set_titles(result, tab_titles) +# derivation of number of rows column header takes +cps <- col_paths(result)[[1]] +cps <- cps[seq(from = 1, by = 2, length.out = length(cps) / 2)] +### as showcolcounts = TRUE, 1 extra row in columns +levels_cols <- length(cps) + 1 + +bordmat <- junco:::make_header_bordmat(obj = result) +if (levels_cols < length(top_left(result))) { + # Create extra_row(s) based on the difference between top_left length and levels_cols + num_extra_rows <- length(top_left(result)) - levels_cols + for (i in 1:num_extra_rows) { + extra_row <- rep(0, ncol(bordmat)) + bordmat <- rbind(extra_row, bordmat) + } + rownames(bordmat) <- NULL +} + ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(34, 19, 19, 21, 17, 19) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") +colwidth <- c(64, 19, 17, 21, 17, 19) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, border_mat = bordmat, label_width_ins = 2.4, orientation = "landscape") diff --git a/tests/testthat/source_code/tsidem01.R b/tests/testthat/source_code/tsidem01.R index d4dab9a9..1fbe4008 100644 --- a/tests/testthat/source_code/tsidem01.R +++ b/tests/testthat/source_code/tsidem01.R @@ -1,26 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsidem01 -## R version: 4.2.1 -## Short Description: Program to create tsidem01: Demographics and Baseline Characteristics -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS -## Output: tsidem01.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -43,12 +20,91 @@ popfl <- "FASFL" trtvar <- "TRT01P" ctrl_grp <- "Placebo" +# Flag to indicate whether IQR should be presented in the table +add_interquartile_range <- FALSE + +.stats_tbl <- c( + "n", + "mean_sd", + "median", + "range", + "count_fraction", + if (add_interquartile_range) "quantiles" else NULL +) + ################################################################################ # Initial Read in of adsl dataset ################################################################################ -adsl <- adsl_jnj %>% - labelled::set_variable_labels(COUNTRY = "Country/Territory") +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + SEX = factor( + case_when(SEX == "M" ~ "Male", SEX == "F" ~ "Female", TRUE ~ SEX), + levels = c("Male", "Female", "Intersex", "Unknown") + ), + COUNTRY = factor( + case_when(COUNTRY == "USA" ~ "United States", TRUE ~ NA_character_) + ), + RACE = factor( + case_when( + RACE == "AMERICAN INDIAN OR ALASKA NATIVE" ~ "American Indian or Alaska Native", + RACE == "ASIAN" ~ "Asian", + RACE == "BLACK OR AFRICAN AMERICAN" ~ "Black or African American", + RACE == "NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER" ~ "Native Hawaiian or other Pacific Islander", + RACE == "WHITE" ~ "White", + RACE == "MULTIPLE" ~ "Multiple", + RACE == "NOT REPORTED" ~ "Not reported", + RACE == "UNKNOWN" ~ "Unknown", + RACE == "OTHER" ~ "Other" + ), + levels = c( + "American Indian or Alaska Native", + "Asian", + "Black or African American", + "Native Hawaiian or other Pacific Islander", + "White", + "Multiple", + "Not reported", + "Unknown", + "Other" + ) + ), + ETHNIC = factor( + case_when( + ETHNIC == "HISPANIC OR LATINO" ~ "Hispanic or Latino", + ETHNIC == "NOT HISPANIC OR LATINO" ~ "Not Hispanic or Latino", + ETHNIC == "NOT REPORTED" ~ "Not reported", + ETHNIC == "UNKNOWN" ~ "Unknown" + ), + levels = c( + "Hispanic or Latino", + "Not Hispanic or Latino", + "Not reported", + "Unknown" + ) + ), + BMIBLG1 = factor( + .data[["BMIBLG1"]], + levels = c("Underweight <18.5", "Normal >=18.5 to <25", "Overweight >=25 to <30", "Obese >=30") + ), + WGTGR1 = factor(.data[["WGTGR1"]], levels = c("<30", ">=30 to <60", ">=60 to <90", ">=90")) + ) |> + labelled::set_variable_labels( + COUNTRY = "Country/Territory", + SEX = "Sex", + AGE = "Age (years)", + RACE = "Race", + ETHNIC = "Ethnicity", + BMIBLG1 = "BMI at Baseline Group 1", + WGTGR1 = "Weight Group 1", + REGION1 = "Region", + BSABL = paste0("Body surface area (m~[super 2])"), + BMIBL = paste0("Body mass index (kg/m~[super 2])") + ) ################################################################################ # Further script level parameters, after having read in main data @@ -71,6 +127,9 @@ demog_vars <- c( ) ## make it named vars so that demog_vars[xx] with xx subset of vars still works names(demog_vars) <- demog_vars + +## to assign precision and post processing +demog_displ_vars <- demog_vars ## retrieve labels demog_labels <- formatters::var_labels(adsl)[demog_vars] @@ -88,19 +147,6 @@ cat_vars <- intersect(cat_vars, demog_vars) # categorical vars get ", n (%)" added into the label demog_labels[cat_vars] <- paste0(demog_labels[cat_vars], ", n (%)") -### vars that have _decode version : use these instead of the original version -vars_decode <- paste0(demog_vars, "_DECODE") - -demog_displ_vars <- tibble(orig = demog_vars, displ = vars_decode) %>% - mutate(displ_exist = displ %in% names(adsl)) %>% - mutate(finalvar = ifelse(displ_exist, displ, orig)) %>% - pull(finalvar) - - -BMIBLG1_avar <- intersect(demog_displ_vars, c("BMIBLG1", "BMIBLG1_DECODE")) -WGTGR1_avar <- intersect(demog_displ_vars, c("WGTGR1", "WGTGR1_DECODE")) -AGEGR1_avar <- intersect(demog_displ_vars, c("AGEGR1", "AGEGR1_DECODE")) - ## JJCS standards: split >= 65 into 2 levels new_age_levels <- list(c(">=65"), list(c(">=65 to <75", ">=75"))) @@ -108,25 +154,26 @@ new_age_levels <- list(c(">=65"), list(c(">=65 to <75", ">=75"))) ### For BMIBLG1 :add ", n(%)" to the levels of the variable -- not ideal, but the easiest way to get it done -levelsBMI <- levels(adsl[[BMIBLG1_avar]]) -adsl[[BMIBLG1_avar]] <- factor( - as.character(adsl[[BMIBLG1_avar]]), +levelsBMI <- levels(adsl$BMIBLG1) +adsl$BMIBLG1 <- factor( + as.character(adsl$BMIBLG1), levels = levelsBMI, labels = paste0(levelsBMI, ", n (%)") ) ### For WGTGR1 :add ", n(%)" to the levels of the variable -- not ideal, but the easiest way to get it done -levelsWGT <- levels(adsl[[WGTGR1_avar]]) -adsl[[WGTGR1_avar]] <- factor( - as.character(adsl[[WGTGR1_avar]]), + +levelsWGT <- levels(adsl$WGTGR1) +adsl$WGTGR1 <- factor( + as.character(adsl$WGTGR1), levels = levelsWGT, labels = paste0(levelsWGT, ", n (%)") ) # to ensure alphabetical ordering, as COUNTRY_DECODE is factor with order according COUNTRY, which is alphabetical on 3-letter code -adsl$COUNTRY_DECODE <- factor( - as.character(adsl$COUNTRY_DECODE), - levels = sort(unique(as.character(adsl$COUNTRY_DECODE))) +adsl$COUNTRY <- factor( + as.character(adsl$COUNTRY), + levels = sort(unique(as.character(adsl$COUNTRY))) ) ################################################################################ @@ -134,12 +181,12 @@ adsl$COUNTRY_DECODE <- factor( ################################################################################ ## restrict to core variables only and restrict to population -adsl <- adsl %>% +adsl <- adsl |> select( USUBJID, starts_with("TRT01"), - all_of(c(demog_vars, demog_displ_vars, popfl, "AGEGR1N")) - ) %>% + all_of(c(demog_vars, popfl, "AGEGR1N")) + ) |> filter(.data[[popfl]] == "Y") @@ -163,7 +210,7 @@ prec_var <- function(var, cap = 4) { decimal = cap, precisionby = NULL, precisionon = var - ) %>% + ) |> pull(decimal) cat(paste("Precision of variable", var, ":", prec, "\n")) @@ -171,17 +218,20 @@ prec_var <- function(var, cap = 4) { return(prec) } -prec_age <- prec_var("AGE") -prec_weightbl <- prec_var("WEIGHTBL") -prec_heightbl <- prec_var("HEIGHTBL") -prec_bmibl <- prec_var("BMIBL") -prec_bsabl <- prec_var("BSABL") +# list here all numerical formats with their d - either manually or via prec_var, + +var_d <- c("AGE" = prec_var("AGE"), "WEIGHTBL" = 1, "HEIGHTBL" = 1, "BMIBL" = 1, "BSABL" = 1) + +# need formats for all variables, including categorical ones +demog_vars_d <- rep(0, length(demog_vars)) +names(demog_vars_d) <- names(demog_vars) +### set categorical ones to proper d +demog_vars_d[names(var_d)] <- var_d -# precision is set manually, the above is just for checking -# note that current precision has been capped to decimal 1 in the below (even for the 2 parameters with higher precision in the database: BMIBL and BSABL) +fmt_d <- fmt_spec_var_d(demog_vars_d, stats_in = .stats_tbl, fmt_d_def = junco_def_d_all, fmt_d_in = NULL) -### AGEGR1 needs special attention -pos_AGEGR1 <- which(demog_displ_vars == AGEGR1_avar) +### AGEGR1 needs special attention - as need an extra combined age level +pos_AGEGR1 <- which(demog_displ_vars == "AGEGR1") if (identical(pos_AGEGR1, integer(0))) { P1 <- 1:length(demog_displ_vars) @@ -189,25 +239,9 @@ if (identical(pos_AGEGR1, integer(0))) { P1 <- 1:(pos_AGEGR1 - 1) } -# set numerical precision : only AGE is in P1 : precision d = 0 -P1_precision <- jjcs_num_formats(d = 0)$fmt - - P2 <- (pos_AGEGR1 + 1):length(demog_displ_vars) ### If AGEGR1 is the last var to be displayed, P2 can be ignored -### further split P2 in calls: different precision is needed for WEIGHTBL, HEIGHTBL (input data as 1 digit) and BMIBL, BSA (input data as 2 digits) -pos_BMIBL <- which(demog_displ_vars == "BMIBL") -P2a <- P2[P2 < pos_BMIBL] -P2b <- P2[P2 >= pos_BMIBL] - -# set numerical precision P2a: WEIGHTBL, HEIGHTBL : precision d = 1 -P2a_precision <- jjcs_num_formats(d = 1)$fmt -# Per communication of Joyce: leave BMI and BSA to precision 1 as well -# set numerical precision P2b: BMIBL, BSA : precision d = 1 -### hence, the splitting up of P2 into P2a and P2b is not really needed, but kept to demonstrate how this could be achieved -P2b_precision <- jjcs_num_formats(d = 1)$fmt - ################################################################################ # Define layout and build table: ################################################################################ @@ -215,39 +249,38 @@ P2b_precision <- jjcs_num_formats(d = 1)$fmt lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - add_overall_col("Total") %>% - append_topleft("Characteristic") %>% + ) |> + split_cols_by(trtvar) |> + add_overall_col("Total") |> + append_topleft("Characteristic") |> ### analyze vars prior to AGEGR1 analyze( vars = demog_displ_vars[P1], var_labels = demog_labels[P1], afun = a_summary, extra_args = list( - .stats = c("n", "mean_sd", "median", "range", "count_fraction"), - .labels = c("n" = "N", "range" = "Min, max"), - .formats = c(P1_precision, - n = jjcsformat_xx("xx"), - "count_fraction" = jjcsformat_count_fraction - ), + .stats = .stats_tbl, + .labels = c("n" = "N", "range" = "Min, max", "quantiles" = "Interquartile range"), + .formats = "default", .indent_mods = c( "n" = 0L, "mean_sd" = 1L, "median" = 1L, "range" = 1L, - "count_fraction" = 1L + "count_fraction" = 1L, + "quantiles" = 1L ) - ) + ), + format = fmt_d # ,section_div = " " - ) %>% + ) |> ### special requirements for AGEGR1 : add extra combined level analyze( - vars = AGEGR1_avar, + vars = "AGEGR1", afun = a_freq_j, extra_args = list( denom = "n_df", @@ -256,52 +289,30 @@ lyt <- basic_table( addstr2levs = ", n (%)", .stats = c("count_unique_fraction") ) - ) %>% + ) |> ### continue with the remainder vars (if AGEGR1 is not the last variable) analyze( - vars = demog_displ_vars[P2a], - var_labels = demog_labels[P2a], - afun = a_summary, - extra_args = list( - .stats = c("n", "mean_sd", "median", "range", "count_fraction"), - .labels = c("n" = "N", "range" = "Min, max"), - .formats = c(P2a_precision, - n = jjcsformat_xx("xx"), - "count_fraction" = jjcsformat_count_fraction - ), - .indent_mods = c( - "n" = 0L, - "mean_sd" = 1L, - "median" = 1L, - "range" = 1L, - "count_fraction" = 1L - ) - ) - # ,section_div = " " - ) %>% - analyze( - vars = demog_displ_vars[P2b], - var_labels = demog_labels[P2b], + vars = demog_displ_vars[P2], + var_labels = demog_labels[P2], afun = a_summary, extra_args = list( - .stats = c("n", "mean_sd", "median", "range", "count_fraction"), - .labels = c("n" = "N", "range" = "Min, max"), - .formats = c(P2b_precision, - n = jjcsformat_xx("xx"), - "count_fraction" = jjcsformat_count_fraction - ), + .stats = .stats_tbl, + .labels = c("n" = "N", "range" = "Min, max", "quantiles" = "Interquartile range"), + .formats = "default", .indent_mods = c( "n" = 0L, "mean_sd" = 1L, "median" = 1L, "range" = 1L, - "count_fraction" = 1L + "count_fraction" = 1L, + "quantiles" = 1L ) - ) + ), + format = fmt_d, # ,section_div = " " ) -result <- build_table(lyt, adsl) +result <- build_table(lyt, adsl, round_type = "sas") ################################################################################ # Post-Processing: @@ -315,13 +326,13 @@ result <- build_table(lyt, adsl) section_div(result, only_sep_sections = TRUE) <- " " # remove N and label for BMI, AGEGR1, WGTGR1 (only label) -tt_at_path(result, path = c(BMIBLG1_avar, "n")) <- NULL +tt_at_path(result, path = c("BMIBLG1", "n")) <- NULL -tt_at_path(result, path = c(WGTGR1_avar, "n")) <- NULL +tt_at_path(result, path = c("WGTGR1", "n")) <- NULL -label_at_path(result, path = c(AGEGR1_avar)) <- NULL -label_at_path(result, path = c(BMIBLG1_avar)) <- NULL -label_at_path(result, path = c(WGTGR1_avar)) <- NULL +label_at_path(result, path = c("AGEGR1")) <- NULL +label_at_path(result, path = c("BMIBLG1")) <- NULL +label_at_path(result, path = c("WGTGR1")) <- NULL # Remove some section dividers : after AGE, BMIBL, WEIGHTBL rpths <- row_paths(result) @@ -368,17 +379,21 @@ upd_indent_mod <- function(result, var, levels, addindent) { result <- upd_indent_mod( result, - var = BMIBLG1_avar, - levels = levels(adsl[[BMIBLG1_avar]]), - addindent = rep(1, times = length(levels(adsl[[BMIBLG1_avar]]))) + var = "BMIBLG1", + levels = levels(adsl$BMIBLG1), + addindent = rep(1, times = length(levels(adsl$BMIBLG1))) ) result <- upd_indent_mod( result, - var = WGTGR1_avar, - levels = levels(adsl[[WGTGR1_avar]]), - addindent = rep(1, times = length(levels(adsl[[WGTGR1_avar]]))) + var = "WGTGR1", + levels = levels(adsl$WGTGR1), + addindent = rep(1, times = length(levels(adsl$WGTGR1))) ) +result <- result |> + prune_table( + prune_func = prune_empty_level + ) ################################################################################ # Add titles and footnotes: ################################################################################ @@ -389,6 +404,7 @@ result <- set_titles(result, titles) # Convert to tbl file and output table: ################################################################################ + colwidth <- c(64, 27, 27, 27, 27) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsidem02.R b/tests/testthat/source_code/tsidem02.R index d8e8a8b2..b4a0a889 100644 --- a/tests/testthat/source_code/tsidem02.R +++ b/tests/testthat/source_code/tsidem02.R @@ -1,26 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsidem02 -## R version: 4.2.1 -## Short Description: Program to create tsidem02: Subjects by Region, Country, and Site -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS -## Output: tsidem02.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -39,8 +16,7 @@ titles <- list( main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) -popfls <- c("SAFFL", "ITTFL", "FASFL") -popfl <- popfls[1] +popfl <- "FASFL" trtvar <- "TRT01P" ctrl_grp <- "Placebo" @@ -48,38 +24,34 @@ ctrl_grp <- "Placebo" # Initial Read in of adsl dataset ################################################################################ -adsl <- adsl_jnj +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ), + COUNTRY = factor( + case_when(COUNTRY == "USA" ~ "United States", TRUE ~ NA_character_) + ) + ) ################################################################################ # Further script level parameters, after having read in main data ################################################################################ demog_vars <- c("REGION1", "COUNTRY", "SITEID") -## make it named vars so that demog_vars[xx] with xx subset of vars still works -names(demog_vars) <- demog_vars -## retrieve labels -demog_labels <- formatters::var_labels(adsl)[demog_vars] - -### vars that have _decode version : use these instead of the original version -vars_decode <- paste0(demog_vars, "_DECODE") - -demog_displ_vars <- tibble(orig = demog_vars, displ = vars_decode) %>% - mutate(displ_exist = displ %in% names(adsl)) %>% - mutate(finalvar = ifelse(displ_exist, displ, orig)) %>% - pull(finalvar) ################################################################################ # Process data: ################################################################################ # filter and restrict to population of interest -adsl <- adsl %>% - filter(.data[[popfl]] == "Y") %>% +adsl <- adsl |> + filter(.data[[popfl]] == "Y") |> select( USUBJID, starts_with("TRT01"), - all_of(popfls), - all_of(unique(c(demog_vars, demog_displ_vars))) + all_of(unique(c(demog_vars))) ) @@ -88,14 +60,14 @@ adsl$colspan_trt <- factor( levels = c("Active Study Agent", " ") ) -# to ensure alphabetical ordering, as COUNTRY_DECODE is factor with order according COUNTRY, which is alphabetical on 3-letter code +# to ensure alphabetical ordering, as COUNTRY is factor with order according COUNTRY levels, which is alphabetical on 3-letter code adsl$REGION1 <- factor( as.character(adsl$REGION1), levels = sort(unique(as.character(adsl$REGION1))) ) -adsl$COUNTRY_DECODE <- factor( - as.character(adsl$COUNTRY_DECODE), - levels = sort(unique(as.character(adsl$COUNTRY_DECODE))) +adsl$COUNTRY <- factor( + as.character(adsl$COUNTRY), + levels = sort(unique(as.character(adsl$COUNTRY))) ) colspan_trt_map <- create_colspan_map( @@ -114,33 +86,38 @@ colspan_trt_map <- create_colspan_map( lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - add_overall_col("Total") %>% + ) |> + split_cols_by(trtvar) |> + add_overall_col("Total") |> split_rows_by( "REGION1", split_label = "Region", - split_fun = trim_levels_in_group("COUNTRY_DECODE"), + split_fun = trim_levels_in_group("COUNTRY"), label_pos = "topleft", section_div = " " - ) %>% - summarize_row_groups("REGION1") %>% + ) |> + summarize_row_groups("REGION1", cfun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) |> split_rows_by( - "COUNTRY_DECODE", + "COUNTRY", split_label = "Country/Territory", split_fun = trim_levels_in_group("SITEID"), label_pos = "topleft", section_div = " " - ) %>% - summarize_row_groups("COUNTRY_DECODE") %>% - analyze_vars("SITEID", denom = "N_col", .stats = c("count_fraction")) %>% + ) |> + summarize_row_groups("COUNTRY", cfun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) |> + analyze_vars( + "SITEID", + denom = "N_col", + .stats = "count_fraction", + .formats = c("count_fraction" = jjcsformat_count_fraction) + ) |> append_topleft(" Site, n (%)") -result <- build_table(lyt, adsl) +result <- build_table(lyt, adsl, round_type = "sas") ################################################################################ # Add titles and footnotes: @@ -152,6 +129,7 @@ result <- set_titles(result, titles) # Convert to tbl file and output table: ################################################################################ -colwidth <- c(43, 23, 23, 23, 25) + +colwidth <- c(30, 23, 23, 23, 25) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsidem03.R b/tests/testthat/source_code/tsidem03.R new file mode 100644 index 00000000..612560e3 --- /dev/null +++ b/tests/testthat/source_code/tsidem03.R @@ -0,0 +1,110 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSIDEM03" +fileid <- write_path(opath, tblid) +titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +popfl <- "FASFL" +trtvar <- "TRT01P" +ctrl_grp <- "Placebo" + +################################################################################ +# Initial Read in of adsl dataset +################################################################################ + +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") + ) + ) |> + filter(.data[[popfl]] == "Y") + +# Identify the STRAT columns +stratd_cols <- grep("^STRAT\\d+D$", names(adsl), value = TRUE) + +# Sort them in numeric order +stratd_cols <- stratd_cols[order(as.numeric(gsub("\\D", "", stratd_cols)))] + +# to create labels list +stratd_labels <- lapply(stratd_cols, function(x) attr(adsl[[x]], "label")) + +# To pull labels of STRATxD variables from ADSL +stratr_cols <- sub(".$", "R", stratd_cols) + +strat_cols <- c(stratd_cols, stratr_cols) + +# to ensure alphabetical ordering +for (i in seq_along(strat_cols)) { + adsl[[i]] <- factor( + as.character(adsl[[i]]), + levels = sort(unique(as.character(adsl[[i]]))) + ) +} + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +################################################################################ +# Define layout and build table: +################################################################################ + +lyt <- basic_table(show_colcounts = TRUE, colcount_format = "N=xx") |> + split_cols_by("colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map)) |> + split_cols_by(trtvar) |> + add_overall_col("Total") |> + append_topleft("Stratification Factor \n \n Category, n (%)") |> + ### analyze STRATxR variables + analyze( + vars = stratr_cols, + var_labels = stratd_labels, + afun = a_summary, + extra_args = list( + .stats = c("n", "count_fraction"), + .labels = c("n" = "N"), + .formats = c(0L, n = jjcsformat_xx("xx"), "count_fraction" = jjcsformat_count_fraction), + .indent_mods = c("n" = 0L, "count_fraction" = 1L) + ), + section_div = " " + ) + +result <- build_table(lyt, adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(59, 21, 21, 21, 23) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsidev01.R b/tests/testthat/source_code/tsidev01.R new file mode 100644 index 00000000..8dc15097 --- /dev/null +++ b/tests/testthat/source_code/tsidev01.R @@ -0,0 +1,240 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSIDEV01" +fileid <- write_path(opath, tblid) +titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +popfl <- "FASFL" +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" + +################################################################################ +# Initial Read in of adsl dataset +################################################################################ + +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + +dv <- dv_jnj + + +################################################################################ +# Further script level parameters, after having read in main data +################################################################################ +## Optional: Add "REGION1" to demog_vars if regional analysis is required +demog_vars <- c("REGION1", "SITEID") +demog_displ_vars <- demog_vars + +## make it named vars so that demog_vars[xx] with xx subset of vars still works +names(demog_vars) <- demog_vars +## retrieve labels +demog_labels <- formatters::var_labels(adsl)[demog_vars] + +################################################################################ +# Process data: +################################################################################ + +# filter and restrict to population of interest +adsl <- adsl |> + filter(.data[[popfl]] == "Y") |> + select( + USUBJID, + starts_with("TRT01"), + all_of(popfl), + all_of(unique(c(demog_vars, demog_displ_vars))) + ) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +if ("REGION1" %in% demog_vars) { + # to ensure alphabetical ordering according to COUNTRY variable + adsl$REGION1 <- factor( + as.character(adsl$REGION1), + levels = sort(unique(as.character(adsl$REGION1))) + ) +} + + +dv <- dv |> + filter(toupper(DVCAT) == "MAJOR") |> + select(STUDYID, USUBJID, DVSEQ, DVDECOD, DVTERM, DVSTDTC, DVDECOD) |> + mutate( + DVSTDT = as.Date(DVSTDTC), + HASDEVFL = "Y" + ) + +adsl_dev <- adsl |> + inner_join(dv, by = "USUBJID") + +colspan_trt_map <- create_colspan_map( + adsl_dev, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +################################################################################ +# Define layout and build table: +################################################################################ +extra_args <- list( + denom = "n_altdf", + .stats = "count_unique_fraction" +) + +lyt <- basic_table( + top_level_section_div = " ", + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) |> + split_cols_by(trtvar) |> + add_overall_col("Total") +if ("REGION1" %in% demog_vars) { + lyt <- lyt |> + split_rows_by( + "REGION1" + ) |> + summarize_row_groups( + "REGION1", + cfun = a_freq_j, + extra_args = append( + extra_args, + list( + label_fstr = "Region: %s", + .labels_n = "" + ) + ) + ) +} + +lyt <- lyt |> + split_rows_by( + "SITEID", + section_div = " " + ) |> + summarize_row_groups( + "SITEID", + cfun = a_freq_j, + extra_args = append( + extra_args, + list( + label_fstr = "Site: %s", + .labels_n = "", + extrablankline = TRUE + ) + ) + ) |> + split_rows_by( + "HASDEVFL", + split_fun = drop_split_levels + ) |> + summarize_row_groups( + "HASDEVFL", + cfun = a_freq_j, + extra_args = append( + extra_args, + list( + label = "Subjects with major protocol deviations", + .labels_n = "" + ) + ) + ) |> + analyze( + "DVDECOD", + afun = a_freq_j, + extra_args = append( + extra_args, + list( + .labels_n = "" + ) + ) + ) + +result <- build_table(lyt, adsl_dev, alt_counts_df = adsl, round_type = "sas") + +######################################################################################### +# Post-Processing step to sort by descending count based on the "Total" column. +# Sorting is applied hierarchically to Region, Center, and Protocol Deviation rows. +# The "Other" deviation category is explicitly forced to the bottom of the list using +# the lastcat argument. See function documentation for jj_complex_scorefun should you +# require a different sorting behavior. +######################################################################################### + +sort_colpath <- c("Total", "Total") + +if (nrow(adsl_dev) != 0) { + if ("REGION1" %in% demog_vars) { + result <- result |> + sort_at_path( + path = c("REGION1"), + scorefun = jj_complex_scorefun(colpath = sort_colpath) + ) |> + sort_at_path( + path = c("REGION1", "*", "SITEID"), + scorefun = jj_complex_scorefun(colpath = sort_colpath) + ) |> + sort_at_path( + path = c("REGION1", "*", "SITEID", "*", "HASDEVFL", "*", "DVDECOD"), + scorefun = jj_complex_scorefun( + colpath = sort_colpath, + lastcat = "count_unique_fraction.Other" + ) + ) + } else { + result <- result |> + sort_at_path( + path = c("SITEID"), + scorefun = jj_complex_scorefun(colpath = sort_colpath) + ) |> + sort_at_path( + path = c("SITEID", "*", "HASDEVFL", "*", "DVDECOD"), + scorefun = jj_complex_scorefun( + colpath = sort_colpath, + lastcat = "count_unique_fraction.Other" + ) + ) + } +} + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsidev02.R b/tests/testthat/source_code/tsidev02.R new file mode 100644 index 00000000..5fd63597 --- /dev/null +++ b/tests/testthat/source_code/tsidev02.R @@ -0,0 +1,202 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) +library(forcats) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSIDEV02" +fileid <- write_path(opath, tblid) +titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) +popfl <- "FASFL" +trtvar <- "TRT01A" +ctrl_grp <- "Placebo" + + +################################################################################ +# Initial Read in of adsl dataset +################################################################################ + +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) + +adsl <- adsl |> + mutate(SITEID = fct_drop(SITEID)) + + +ie <- ie_jnj + + +################################################################################ +# Further script level parameters, after having read in main data +################################################################################ + +demog_vars <- c("REGION1", "SITEID") +demog_displ_vars <- demog_vars + +## make it named vars so that demog_vars[xx] with xx subset of vars still works +names(demog_vars) <- demog_vars +## retrieve labels +demog_labels <- formatters::var_labels(adsl)[demog_vars] + +################################################################################ +# Process data: +################################################################################ + +# filter and restrict to population of interest +adsl <- adsl |> + filter(.data[[popfl]] == "Y") |> + select( + USUBJID, + STUDYID, + starts_with("TRT01"), + all_of(popfl), + all_of(unique(c(demog_vars, demog_displ_vars))) + ) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +# to ensure alphabetical ordering according to COUNTRY variable +adsl$REGION1 <- factor( + as.character(adsl$REGION1), + levels = sort(unique(as.character(adsl$REGION1))) +) + +ie <- ie |> + select(STUDYID, USUBJID, IECAT, IETEST, IETESTCD) |> + mutate( + IECAT1 = factor(case_when( + IECAT == "INCLUSION" ~ "Subjects who did not meet inclusion criteria", + TRUE ~ NA_character_ + )), + IETSTCD1 = factor(case_when(IECAT == "INCLUSION" ~ IETESTCD, TRUE ~ NA_character_)), + IECAT2 = factor(case_when( + IECAT == "EXCLUSION" ~ "Subjects who met exclusion criteria", + TRUE ~ NA_character_ + )), + IETSTCD2 = factor(case_when(IECAT == "EXCLUSION" ~ IETESTCD, TRUE ~ NA_character_)) + ) |> + filter(!is.na(IECAT)) + +adsl_ie <- adsl |> + inner_join(ie, by = c("STUDYID", "USUBJID")) |> + mutate(SITEID = fct_drop(SITEID)) + +colspan_trt_map <- create_colspan_map( + adsl_ie, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +################################################################################ +# Define layout and build table: +################################################################################ +extra_args <- list( + .stats = "count_unique_fraction" +) + +lyt <- basic_table( + top_level_section_div = " ", + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) |> + split_cols_by(trtvar) |> + add_overall_col("Total") |> + # Subjects who did not meet inclusion criteria + split_rows_by( + "IECAT1", + section_div = " " + ) |> + summarize_row_groups( + var = "IECAT1", + cfun = a_freq_j, + extra_args = append( + extra_args, + list( + denom = "n_altdf", + .labels_n = "" + ) + ) + ) |> + analyze( + "IETSTCD1", + afun = a_freq_j, + extra_args = append( + extra_args, + list( + denom = "n_altdf", + .labels_n = "" + ) + ) + ) |> + # Subjects who met exclusion criteria + split_rows_by( + "IECAT2", + section_div = " " + ) |> + summarize_row_groups( + var = "IECAT2", + cfun = a_freq_j, + extra_args = append( + extra_args, + list( + denom = "n_altdf", + .labels_n = "" + ) + ) + ) |> + analyze( + "IETSTCD2", + afun = a_freq_j, + extra_args = append( + extra_args, + list( + denom = "n_altdf", + .labels_n = "" + ) + ) + ) + +result <- build_table(lyt, adsl_ie, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 17, 17, 19) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsids01.R b/tests/testthat/source_code/tsids01.R index cefeed1e..127b0a2c 100644 --- a/tests/testthat/source_code/tsids01.R +++ b/tests/testthat/source_code/tsids01.R @@ -1,28 +1,3 @@ -############################################################################### -## Original Reporting Effort: Standards -## Program Name: tsids01.R -## R Version: 4.2.1 -## Short Description: Create TSIDS01: Subject Screening and Enrollment -## Author: Johnson & Johnson Innovative Medicine -## Date: 23Feb2024 -## Input: ADSL -## Output: tsids01.rtf -## Remarks: -## R-functions: -## R-function Sample Call: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -############################################################################### - -############################################################################### -# Prep environment -############################################################################### - library(envsetup) library(tern) library(dplyr) @@ -40,21 +15,18 @@ tab_titles <- list( subtitles = NULL, main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" ) - - +ran_enrl_var <- "RANDFL" +if (ran_enrl_var == "RANDFL") { + ran_enrl_lbl <- "randomized" +} else if (ran_enrl_var == "ENRLFL") { + ran_enrl_lbl <- "enrolled" +} ############################################################################### # Process data ############################################################################### -adsl <- adsl_jnj %>% - filter(SCRNFL == "Y") %>% - mutate( - SCRNFL = with_label(.data[["SCRNFL"]] == "Y", "Patients screened"), - SCRFFL = with_label(.data[["SCRFFL"]], "Screening failures"), - RESCRNFL = with_label(.data[["RESCRNFL"]] == "Y", "Subjects re-screened"), - ENRLFL = with_label(.data[["ENRLFL"]] == "Y", "Subjects enrolled"), - RANDFL = with_label(.data[["RANDFL"]] == "Y", "Subjects randomized") - ) %>% +adsl <- adsl_jnj |> + filter(SCRNFL == "Y") |> select( STUDYID, USUBJID, @@ -62,14 +34,10 @@ adsl <- adsl_jnj %>% SCRFFL, DCSCREEN, RESCRNFL, - RANDFL, - ENRLFL, + all_of(ran_enrl_var), TRT01P ) -adsl_unq <- adsl %>% - distinct(STUDYID, USUBJID, .keep_all = TRUE) - ############################################################################### # Define layout and build table ############################################################################### @@ -78,43 +46,78 @@ lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx", top_level_section_div = " " -) %>% - add_overall_col(label = "Total") %>% - split_rows_by("SCRFFL", split_fun = keep_split_levels("Y")) %>% - summarize_num_patients( - var = "USUBJID", - .stats = "unique", - .formats = c("unique" = jjcsformat_count_fraction), - .labels = c(unique = "Screening failures") - ) %>% - count_occurrences( - vars = "DCSCREEN", - drop = FALSE, - .stats = "count_fraction_fixed_dp", - .formats = c("count_fraction_fixed_dp" = jjcsformat_count_fraction) - ) %>% - count_patients_with_flags( - var = "USUBJID", - flag_variables = c("RESCRNFL"), - nested = FALSE, - .stats = "count", - .formats = c("count" = jjcsformat_xx("xx")) - ) %>% - count_patients_with_flags( - var = "USUBJID", - flag_variables = c("RANDFL"), - nested = FALSE, - .stats = "count_fraction", - .formats = c("count_fraction" = jjcsformat_count_fraction) +) |> + add_overall_col(label = "Total") |> + split_rows_by("SCRFFL", split_fun = keep_split_levels("Y")) |> + summarize_row_groups( + "SCRFFL", + cfun = a_freq_j, + extra_args = list( + riskdiff = FALSE, + .stats = c("count_unique_fraction"), + label = "Screening failures" + ) + ) |> + analyze( + "DCSCREEN", + afun = a_freq_j, + extra_args = list( + riskdiff = FALSE, + .stats = c("count_unique_fraction") + ) + ) |> + split_rows_by("RESCRNFL", split_fun = keep_split_levels("Y")) |> + summarize_row_groups( + "RESCRNFL", + cfun = a_freq_j, + extra_args = list( + riskdiff = FALSE, + .stats = c("count_unique"), + label = "Subjects re-screened" + ) + ) |> + analyze( + "SCRFFL", + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + riskdiff = FALSE, + .stats = c("count_unique_fraction"), + val = "Y", + label = "Screening failures", + denom = "n_rowdf" + ) + ) |> + analyze( + ran_enrl_var, + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + riskdiff = FALSE, + .stats = c("count_unique_fraction"), + val = "Y", + label = paste0("Subjects ", ran_enrl_lbl), + denom = "n_rowdf" + ) + ) |> + split_rows_by(ran_enrl_var, split_fun = keep_split_levels("Y")) |> + summarize_row_groups( + ran_enrl_var, + cfun = a_freq_j, + extra_args = list( + riskdiff = FALSE, + .stats = c("count_unique_fraction"), + label = paste0("Subjects ", ran_enrl_lbl) + ) ) - -result <- build_table(lyt, df = adsl, alt_counts_df = adsl_unq) +result <- build_table(lyt, df = adsl, alt_counts_df = adsl, round_type = "sas") ############################################################################### # Post-processing ############################################################################### # Post-processing step to sort by descending count in the Combined column + result <- sort_at_path( tt = result, path = c("root", "SCRFFL", "Y", "DCSCREEN"), @@ -122,43 +125,27 @@ result <- sort_at_path( spanningheadercolvar = NULL, colpath = c("Total", "Total"), firstcat = NULL, - lastcat = "Other" + lastcat = "count_unique_fraction.Other" ) ) + if (nrow(adsl) == 0) { # Post-processing step to remove table rows with all 0 or NA values result <- safe_prune_table(result, prune_func = prune_empty_level) } else { - # Post-processing step to remove reason for screening failures table rows - # with all 0 or NA values - result <- prune_table( - result, - prune_func = count_pruner( - cat_exclude = c( - "Screening failures" - ), - cols = "Total" - ) - ) - result <- prune_table( - result, - prune_func = count_pruner( - cat_exclude = c( - "Subjects re-screened" - ), - cols = "Total" - ) - ) - result <- prune_table( - result, - prune_func = count_pruner( - cat_exclude = c( - "Subjects randomized" - ), - cols = "Total" - ) - ) + prune_empty_level_tablerow <- function(tt) { + if (is(tt, "ContentRow")) { + return(FALSE) + } + if (is(tt, "TableRow")) { + return(FALSE) + } + kids <- tree_children(tt) + length(kids) == 0 + } + + result <- result |> trim_rows(prune_empty_level_tablerow) } ############################################################################### @@ -171,6 +158,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table ############################################################################### -colwidth <- c(56, 23) + +colwidth <- c(64, 23) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid) diff --git a/tests/testthat/source_code/tsids02.R b/tests/testthat/source_code/tsids02.R index c6b3314f..ff05c27b 100644 --- a/tests/testthat/source_code/tsids02.R +++ b/tests/testthat/source_code/tsids02.R @@ -1,26 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsids02 -## R version: 4.2.1 -## Short Description: Program to create tsids02: Subject Disposition -## Author: Johnson & Johnson Innovative Medicine -## Date: 05JAN2024 -## Input: adsl.R -## Output: tsids02.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -46,7 +23,17 @@ tab_titles <- list( # Process data: ################################################################################ -adsl <- adsl_jnj +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) no_data_to_report <- function(df, var) { if (sum(is.na(df[[var]])) == length(df[[var]])) { @@ -58,8 +45,8 @@ no_data_to_report <- function(df, var) { adsl <- no_data_to_report(df = adsl, var = "DCTREAS") adsl <- no_data_to_report(df = adsl, var = "DCSREAS") -adsl <- adsl %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl |> + filter(!!rlang::sym(popfl) == "Y") |> select( USUBJID, !!rlang::sym(trtvar), @@ -71,19 +58,16 @@ adsl <- adsl %>% EOSSTT, DCSREAS, RACE - ) %>% + ) |> create_colspan_var( non_active_grp = "Placebo", non_active_grp_span_lbl = " ", active_grp_span_lbl = "Active Study Agent", colspan_var = "colspan_trt", trt_var = trtvar - ) %>% - mutate( - rrisk_header = "Risk Difference (%) 95% CI", - rrisk_label = paste(!!rlang::sym(trtvar), "vs Placebo") ) + ################################################################################ # Define layout and build table: ################################################################################ @@ -98,8 +82,14 @@ colspan_trt_map <- create_colspan_map( ) totdf <- tribble( - ~valname, ~label, ~levelcombo, ~exargs, - "Total", "Total", c("Xanomeline High Dose", "Xanomeline Low Dose", "Placebo"), list() + ~valname, + ~label, + ~levelcombo, + ~exargs, + "Total", + "Total", + c("Xanomeline High Dose", "Xanomeline Low Dose", "Placebo"), + list() ) rr_method <- "wald" @@ -115,78 +105,33 @@ lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx", top_level_section_div = " " -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% + ) |> + split_cols_by(trtvar) |> split_cols_by( trtvar, split_fun = add_combo_levels(totdf, keep_levels = "Total"), nested = FALSE - ) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) %>% - # Analysis sets - analyze( - popfl, - var_labels = "Analysis set", - afun = a_freq_j, - extra_args = append( - extra_args_rr, - list(label = "Full", val = "Y", riskdiff = FALSE, NULL) - ), - show_labels = "visible" - ) %>% + ) |> + # Subjects ongoing treatment analyze( - "SAFFL", - afun = a_freq_j, - extra_args = append( - extra_args_rr, - list(label = "Safety", val = "Y", riskdiff = FALSE, NULL) - ), - show_labels = "hidden", - indent_mod = 1 - ) %>% - analyze( - "PPROTFL", - afun = a_freq_j, - extra_args = append( - extra_args_rr, - list( - label = "Per protocol", - val = "Y", - riskdiff = FALSE, - extrablankline = TRUE, - NULL - ) - ), - show_labels = "hidden", - indent_mod = 1, - na_str = " " - ) %>% - # Ongoing - analyze( - "EOSSTT", + "EOTSTT", show_labels = "hidden", afun = a_freq_j, extra_args = append( extra_args_rr, list( - label = "Subjects ongoing", + label = "Subjects ongoing treatment", val = "ONGOING", riskdiff = FALSE, - extrablankline = TRUE, NULL ) ), na_str = " " - ) %>% + ) |> # Treatment disposition analyze( "EOTSTT", @@ -197,7 +142,7 @@ lyt <- basic_table( extra_args_rr, list(label = "Completed treatment", val = "COMPLETED", NULL) ) - ) %>% + ) |> analyze( "EOTSTT", table_names = "DC_Trt", @@ -207,7 +152,7 @@ lyt <- basic_table( extra_args_rr, list(label = "Discontinued treatment", val = "DISCONTINUED", NULL) ) - ) %>% + ) |> analyze( "DCTREAS", show_labels = "hidden", @@ -215,7 +160,23 @@ lyt <- basic_table( afun = a_freq_j, na_str = " ", extra_args = append(extra_args_rr, list(extrablankline = TRUE)) - ) %>% + ) |> + # Subjects ongoing study + analyze( + "EOSSTT", + show_labels = "hidden", + afun = a_freq_j, + extra_args = append( + extra_args_rr, + list( + label = "Subjects ongoing study", + val = "ONGOING", + riskdiff = FALSE, + NULL + ) + ), + na_str = " " + ) |> # Study disposition analyze( "EOSSTT", @@ -226,7 +187,7 @@ lyt <- basic_table( extra_args_rr, list(label = "Completed study", val = "COMPLETED", NULL) ) - ) %>% + ) |> analyze( "EOSSTT", show_labels = "hidden", @@ -236,7 +197,7 @@ lyt <- basic_table( extra_args_rr, list(label = "Discontinued study", val = "DISCONTINUED", NULL) ) - ) %>% + ) |> analyze( "DCSREAS", show_labels = "hidden", @@ -245,34 +206,31 @@ lyt <- basic_table( extra_args = append(extra_args_rr, NULL) ) -result <- build_table(lyt, adsl) +result <- build_table(lyt, adsl, round_type = "sas") ################################################################################ # Post-Processing ################################################################################ -## Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result, span_label_var = "rrisk_header") - -result <- result %>% +result <- result |> sort_at_path( path = c( - "ma_FASFL_SAFFL_PPROTFL_EOSSTT_Compl_Trt_DC_Trt_DCTREAS_Compl_Study_DC_Study_DCSREAS", + "ma_EOTSTT_Compl_Trt_DC_Trt_DCTREAS_EOSSTT_Compl_Study_DC_Study_DCSREAS", "DCTREAS" ), scorefun = jj_complex_scorefun(colpath = "Total", lastcat = "Other") - ) %>% + ) |> sort_at_path( path = c( - "ma_FASFL_SAFFL_PPROTFL_EOSSTT_Compl_Trt_DC_Trt_DCTREAS_Compl_Study_DC_Study_DCSREAS", + "ma_EOTSTT_Compl_Trt_DC_Trt_DCTREAS_EOSSTT_Compl_Study_DC_Study_DCSREAS", "DCSREAS" ), - scorefun = jj_complex_scorefun(colpath = "Total", lastcat = "Other") + scorefun = jj_complex_scorefun(colpath = "Total", lastcat = "count_unique_fraction.Other") ) # Prune data driven output. -result <- result %>% - safe_prune_table(prune_func = keep_rows(keep_non_null_rows)) %>% +result <- result |> + safe_prune_table(prune_func = keep_rows(keep_non_null_rows)) |> safe_prune_table( prune_func = count_pruner( cols = c("colspan_trt"), @@ -285,20 +243,6 @@ result <- result %>% ) ) -# Prune data driven output. -result <- result %>% - safe_prune_table(prune_func = keep_rows(keep_non_null_rows)) %>% - safe_prune_table( - prune_func = count_pruner( - cols = c("colspan_trt"), - cat_exclude = c( - "Completed study", - "Completed treatment", - "Discontinued study", - "Discontinued treatment" - ) - ) - ) ################################################################################ # Add titles and footnotes: @@ -309,6 +253,7 @@ result <- set_titles(result, tab_titles) # Convert to tbl file and output table: ################################################################################ -colwidth <- c(38, 23, 23, 23, 25, 37, 37) + +colwidth <- c(44, 21, 21, 21, 23) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsids02a.R b/tests/testthat/source_code/tsids02a.R deleted file mode 100644 index 61fd993c..00000000 --- a/tests/testthat/source_code/tsids02a.R +++ /dev/null @@ -1,299 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsids02a -## R version: 4.2.1 -## Short Description: Program to create tsids02a: Subject Disposition by subgroup -## Author: Johnson & Johnson Innovative Medicine -## Date: 05JAN2024 -## Input: adsl.R -## Output: tsids02a.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define output ID and file location: -################################################################################ - -tblid <- "TSIDS02a" -fileid <- write_path(opath, tblid) -popfl <- "FASFL" -trtvar <- "TRT01P" -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - - -################################################################################ -# Process data: -################################################################################ - -adsl <- adsl_jnj - -no_data_to_report <- function(df, var) { - if (sum(is.na(df[[var]])) == length(df[[var]])) { - df[[var]] <- factor(NA_character_, levels = "No data to report") - } - return(df) -} - -adsl <- no_data_to_report(df = adsl, var = "DCTREAS") -adsl <- no_data_to_report(df = adsl, var = "DCSREAS") - -adsl <- adsl %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select( - USUBJID, - !!rlang::sym(trtvar), - !!rlang::sym(popfl), - SAFFL, - PPROTFL, - EOTSTT, - DCTREAS, - EOSSTT, - DCSREAS, - RACE_DECODE - ) %>% - create_colspan_var( - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar - ) %>% - mutate( - rrisk_header = "Risk Difference (%) 95% CI", - rrisk_label = paste(!!rlang::sym(trtvar), "vs Placebo") - ) - -# Added since label_fstr not working with cpct_relrisk -adsl$RACE <- as.factor(as.character(ifelse( - is.na(adsl$RACE_DECODE), - NA, - paste("Race:", adsl$RACE_DECODE) -))) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) -ref_path <- c("colspan_trt", " ", trtvar, "Placebo") - -################################################################################ -# Define layout and build table: -################################################################################ - -totdf <- tribble( - ~valname, ~label, ~levelcombo, ~exargs, - "Total", "Total", c("Xanomeline High Dose", "Xanomeline Low Dose", "Placebo"), list() -) - - -extra_args1 <- list( - denom = "n_altdf", - denom_by = "RACE", - riskdiff = FALSE, - .stats = "count_unique" -) -extra_args2 <- list( - denom = "n_altdf", - denom_by = "RACE", - riskdiff = FALSE, - .stats = "count_unique_fraction" -) -extra_args3 <- list( - denom = "n_altdf", - denom_by = "RACE", - riskdiff = TRUE, - method = "wald", - .stats = "count_unique_fraction", - ref_path = ref_path -) - - -lyt <- basic_table( - show_colcounts = TRUE, - colcount_format = "N=xx", - top_level_section_div = " " -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - split_cols_by( - trtvar, - split_fun = add_combo_levels(totdf, keep_levels = "Total"), - nested = FALSE - ) %>% - split_cols_by("rrisk_header", nested = FALSE) %>% - split_cols_by( - trtvar, - labels_var = "rrisk_label", - split_fun = remove_split_levels("Placebo") - ) %>% - split_rows_by("RACE", split_fun = drop_split_levels, section_div = " ") %>% - summarize_row_groups( - "RACE", - cfun = a_freq_j, - indent_mod = 0L, - # na_str = " ", - extra_args = extra_args1 - ) %>% - # Analysis sets - analyze( - popfl, - var_labels = "Analysis set:", - afun = a_freq_j, - extra_args = append(extra_args2, list(label = "Full", val = "Y")), - show_labels = "visible" - ) %>% - analyze( - "SAFFL", - afun = a_freq_j, - extra_args = append(extra_args2, list(label = "Safety", val = "Y")), - show_labels = "hidden", - indent_mod = 1 - ) %>% - analyze( - "PPROTFL", - afun = a_freq_j, - extra_args = append( - extra_args2, - list(label = "Per protocol", val = "Y", extrablankline = TRUE) - ), - show_labels = "hidden", - indent_mod = 1, - na_str = " " - ) %>% - # Ongoing - analyze( - "EOSSTT", - show_labels = "hidden", - afun = a_freq_j, - na_str = " ", - extra_args = append( - extra_args2, - list(val = "ONGOING", label = "Subjects ongoing", extrablankline = TRUE) - ) - ) %>% - # Treatment disposition - analyze( - "EOTSTT", - table_names = "Compl_Trt", - show_labels = "hidden", - afun = a_freq_j, - extra_args = append( - extra_args3, - list(label = "Completed treatment", val = "COMPLETED") - ) - ) %>% - analyze( - "EOTSTT", - table_names = "DC_Trt", - show_labels = "hidden", - afun = a_freq_j, - extra_args = append( - extra_args3, - list(label = "Discontinued treatment", val = "DISCONTINUED") - ) - ) %>% - analyze( - "DCTREAS", - show_labels = "hidden", - indent_mod = 1, - afun = a_freq_j, - extra_args = append( - extra_args3, - list(extrablankline = TRUE, drop_levels = TRUE) - ) - ) %>% - # Study disposition - analyze( - "EOSSTT", - table_names = "Compl_Study", - show_labels = "hidden", - afun = a_freq_j, - extra_args = append( - extra_args3, - list(label = "Completed study", val = "COMPLETED") - ) - ) %>% - analyze( - "EOSSTT", - show_labels = "hidden", - table_names = "DC_Study", - afun = a_freq_j, - extra_args = append( - extra_args3, - list(label = "Discontinued study", val = "DISCONTINUED") - ) - ) %>% - analyze( - "DCSREAS", - show_labels = "hidden", - indent_mod = 1, - afun = a_freq_j, - extra_args = append(extra_args3, list(drop_levels = TRUE)) - ) - -result <- build_table(lyt, adsl, alt_counts_df = adsl) - -################################################################################ -# Post-Processing -################################################################################ - -# Remove the N=xx column headers for the risk difference columns -result <- remove_col_count(result, span_label_var = "rrisk_header") - -# Sort DCTREAS and DCSREAD by descending total column. -result <- result %>% - sort_at_path( - path = c("RACE", "*", "DCTREAS"), - scorefun = jj_complex_scorefun(colpath = "Total", lastcat = "Other") - ) %>% - sort_at_path( - path = c("RACE", "*", "DCSREAS"), - scorefun = jj_complex_scorefun(colpath = "Total") - ) - -result <- prune_table( - result, - prune_func = remove_rows(removerowtext = "No data to report") -) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table: -################################################################################ - -colwidth <- c(64, 23, 23, 23, 23, 35, 35) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsids02b.R b/tests/testthat/source_code/tsids02b.R new file mode 100644 index 00000000..6c0d37b5 --- /dev/null +++ b/tests/testthat/source_code/tsids02b.R @@ -0,0 +1,368 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSIDS02b" +fileid <- write_path(opath, tblid) +popfl <- "ENRLFL" +trtvar <- "TRT01P" +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +################################################################################ +# Process data: +################################################################################ + +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select( + STUDYID, + USUBJID, + !!rlang::sym(trtvar), + !!rlang::sym(popfl), + EOTSTT, + DCTREAS, + EOSSTT, + DCSREAS, + ) |> + create_colspan_var( + non_active_grp = "Placebo", + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) + +# Actual Dataset +addisp1 <- addisp_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + select(USUBJID, PARAMCD, AVALC) + +# Create treatment names +addisp2 <- addisp_jnj |> + filter(!!rlang::sym(popfl) == "Y" & !is.na(DSSCAT) & DSSCAT != "") |> + select(USUBJID, DSSCAT) + +a <- tolower(unique(addisp2$DSSCAT)) + + +addisp <- addisp1 |> + tidyr::pivot_wider( + names_from = c(PARAMCD), + values_from = AVALC + ) |> + mutate( + ONGOING_SUB = case_when( + rowSums(dplyr::across(dplyr::starts_with("EOTS"), ~ toupper(.x) == "ONGOING"), na.rm = TRUE) > 0 ~ "Y", + TRUE ~ NA_character_ + ), + COMPL_SUB = dplyr::case_when( + rowSums(dplyr::across(dplyr::starts_with("EOTS"), ~ toupper(.x) == "COMPLETED"), na.rm = TRUE) == + rowSums(!is.na(dplyr::across(dplyr::starts_with("EOTS")))) & + rowSums(!is.na(dplyr::across(dplyr::starts_with("EOTS")))) > 0 ~ + "Y", + TRUE ~ NA_character_ + ), + DISC_BOTH_TREATMENT = dplyr::case_when( + rowSums(dplyr::across(dplyr::starts_with("EOTS"), ~ toupper(.x) == "DISCONTINUED"), na.rm = TRUE) == + rowSums(!is.na(dplyr::across(dplyr::starts_with("EOTS")))) & + rowSums(!is.na(dplyr::across(dplyr::starts_with("EOTS")))) > 0 ~ + "Y", + TRUE ~ NA_character_ + ), + DISC_ONE_TREATMENT = dplyr::case_when( + rowSums(dplyr::across(dplyr::starts_with("EOTS"), ~ toupper(.x) == "DISCONTINUED"), na.rm = TRUE) > 0 ~ "Y", + TRUE ~ NA_character_ + ) + ) |> + mutate( + dplyr::across( + dplyr::starts_with("EOTS"), + ~ dplyr::case_when(toupper(.x) == "COMPLETED" ~ "Y", TRUE ~ NA_character_), + .names = "COMPLETED_{gsub('EOTS|STT', '', .col)}" + ), + dplyr::across( + dplyr::starts_with("EOTS"), + ~ dplyr::case_when(toupper(.x) == "DISCONTINUED" ~ "Y", TRUE ~ NA_character_), + .names = "DISCONTINUED_{gsub('EOTS|STT', '', .col)}" + ) + ) + + +# for counting the treatments +count_trt <- grep("^EOTS", names(addisp), value = TRUE) + +num_words <- c( + "zero", + "one", + "both", + "three", + "four", + "five", + "six", + "seven", + "eight", + "nine", + "ten" +) + +count_label <- num_words[length(count_trt) + 1] + +addisp <- inner_join(addisp, adsl, by = c("USUBJID")) + +# Ensure all pivoted AVALC columns share the same factor levels (mimics SAS format behavior) +avalc_cols <- grep("^(EOTS|DCTS|LTVIST)", names(addisp), value = TRUE) +all_levels <- sort(unique(unlist(lapply(addisp[avalc_cols], function(x) { + if (is.factor(x)) levels(x) else unique(na.omit(x)) +})))) +addisp <- addisp |> + mutate(across(all_of(avalc_cols), ~ factor(.x, levels = all_levels))) + + +################################################################################ +# Define layout and build table: +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = "Placebo", + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +totdf <- tribble( + ~valname, + ~label, + ~levelcombo, + ~exargs, + "Total", + "Total", + c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo"), + list() +) + +rr_method <- "wald" +ref_path <- c("colspan_trt", " ", trtvar, "Placebo") +extra_args_rr <- list( + riskdiff = FALSE, + method = rr_method, + ref_path = ref_path, + .stats = c("count_unique_fraction") +) + + +map1 <- tribble( + ~var, + ~value, + ~label, + "ONGOING_SUB", + "Y", + "Subjects ongoing any treatment", + "COMPL_SUB", + "Y", + "Completed treatment~[super a]", + "DISC_BOTH_TREATMENT", + "Y", + paste("Discontinued", count_label, "study agents"), + "DISC_ONE_TREATMENT", + "Y", + paste("Discontinued one study agent") +) + +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) |> + split_cols_by(trtvar) |> + split_cols_by( + trtvar, + split_fun = add_combo_levels(totdf, keep_levels = "Total"), + nested = FALSE + ) |> + split_rows_by(var = "STUDYID", section_div = "", child_labels = "hidden", parent_name = "STUDYID1") |> + analyze( + vars = c("ONGOING_SUB", "COMPL_SUB", "DISC_BOTH_TREATMENT", "DISC_ONE_TREATMENT"), + afun = a_freq_j, + extra_args = c( + extra_args_rr, + list( + label_map = map1, + val = "Y" + ) + ), + show_labels = "hidden" + ) + + +# calculate how many completed /discontinued treatments. + +comp_vars <- grep("^COMPLETED_[0-9]+$", names(addisp), value = TRUE) +comp_vars <- comp_vars[order(as.integer(sub("COMPLETED_", "", comp_vars)))] + +disc_vars <- grep("^DISCONTINUED_[0-9]+$", names(addisp), value = TRUE) +disc_vars <- disc_vars[order(as.integer(sub("DISCONTINUED_", "", disc_vars)))] + + +agents <- sort(unique( + c( + as.integer(sub("COMPLETED_", "", comp_vars)), + as.integer(sub("DISCONTINUED_", "", disc_vars)) + ) +)) + +agent_map <- setNames(a[seq_along(agents)], agents) + + +for (ag in agents) { + stat_var <- paste0("EOTS", ag, "STT") # <-- dynamic status variable + rs_var <- paste0("DCTS", ag, "RS") # <-- dynamic reason variable + + agent_lbl <- agent_map[[as.character(ag)]] + if (is.null(agent_lbl) || is.na(agent_lbl) || agent_lbl == "") { + # fallback so label never breaks + agent_lbl <- paste0("Treatment ", ag) + } + + ## ---- TREATMENT STATUS/REASONS (nested under discontinued) ---- + + if (rs_var %in% names(addisp)) { + xmap <- data.frame(value = levels(addisp[[rs_var]]), label = levels(addisp[[rs_var]])) + xmap$label[xmap$value == "COMPLETED"] <- paste0("Completed treatment with ", agent_lbl) + xmap$label[xmap$value == "DISCONTINUED"] <- paste0("Discontinued treatment with ", agent_lbl) + + lyt <- lyt |> + split_rows_by( + var = "STUDYID", + section_div = "", + child_labels = "hidden", + nested = FALSE, + parent_name = paste0("STUDYIDag", ag) + ) |> + split_rows_by( + stat_var, + split_fun = keep_split_levels(c("COMPLETED", "DISCONTINUED")), + child_labels = "hidden", + nested = TRUE + ) |> + analyze( + vars = stat_var, + afun = a_two_tier, + extra_args = c( + extra_args_rr, + list( + grp_fun = a_freq_j, + detail_fun = a_freq_j, + inner_var = rs_var, + drill_down_levs = "DISCONTINUED", + drop_levels = TRUE, + label_map = xmap + ) + ) + ) + } +} + +## ---- STUDY STATUS/REASONS (nested under discontinued) ---- +stat_var <- "EOSSTT" +rs_var <- "DCSREAS" + +xmap <- data.frame( + value = c(levels(addisp[[stat_var]]), levels(addisp[[rs_var]])), + label = c(levels(addisp[[stat_var]]), levels(addisp[[rs_var]])) +) +xmap$label[xmap$value == "COMPLETED"] <- "Completed study" +xmap$label[xmap$value == "DISCONTINUED"] <- "Discontinued study" +xmap$label[xmap$value == "ONGOING"] <- "Subjects ongoing study" + +lyt <- lyt |> + split_rows_by( + var = "STUDYID", + section_div = "", + child_labels = "hidden", + nested = FALSE, + parent_name = "STUDYIDlast" + ) |> + split_rows_by( + stat_var, + split_fun = keep_split_levels(c("ONGOING", "COMPLETED", "DISCONTINUED")), + nested = TRUE, + child_labels = "hidden" + ) |> + analyze( + vars = stat_var, + afun = a_two_tier, + extra_args = c( + grp_fun = a_freq_j, + detail_fun = a_freq_j, + inner_var = rs_var, + drill_down_levs = "DISCONTINUED", + list(drop_levels = TRUE, label_map = xmap, .stats = c("count_unique_fraction")) + ) + ) + +result <- build_table(lyt, addisp, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Post-Processing +################################################################################ + +# Add dynamic sorting for each agent's treatment status section +for (ag in agents) { + stat_var <- paste0("EOTS", ag, "STT") # <-- dynamic status variable + + if (stat_var %in% names(addisp)) { + result <- result |> + sort_at_path( + path = c(paste0("STUDYIDag", ag), "*", stat_var, "DISCONTINUED", stat_var), + scorefun = jj_complex_scorefun(colpath = "Total", lastcat = "Other") + ) + } +} + +result <- result |> + sort_at_path( + path = c("STUDYIDlast", "*", "EOSSTT", "DISCONTINUED", "EOSSTT"), + scorefun = jj_complex_scorefun(colpath = "Total", lastcat = "Other") + ) + + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table: +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 23) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsiex01.R b/tests/testthat/source_code/tsiex01.R index f16674e2..65abb457 100644 --- a/tests/testthat/source_code/tsiex01.R +++ b/tests/testthat/source_code/tsiex01.R @@ -1,28 +1,5 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsiex01.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsiex01: Duration of Treatment -## Author: Johnson & Johnson Innovative Medicine -## Date: 08 Feb 2024 -## Input: ADSL, ADEXSUM -## Output: TSIEX01.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) +library(haven) library(tern) library(dplyr) library(rtables) @@ -36,12 +13,15 @@ library(junco) # - Define output ID and file location # - Define treatment variable used (default=TRT01A) # - Define population flag used (default=SAFFL) +# - Define subgroup variable for subgroup analyses (default=NULL, no subgroup) # - Define parameter code needed for duration of treatment # - Conversion to get the unit of PARAMCD selected for treatment # (i.e 1 if original PARAMCD unit is days, 30.4375 if original PARAMCD unit is in months) # - Define levels which will control ordering for AVALCAT1 in the table # - Choose whether or not you want to present a combined active treatment column (default=TRUE) # - Define how to create combined treatment columns (if required) +# - Choose whether or not to include Interquartile range row (default=TRUE) +# - Choose whether or not to include Total treatment (subject years) row (default=TRUE) ################################################################################ tblid <- "TSIEX01" @@ -57,12 +37,21 @@ trtvar <- "TRT01A" popfl <- "SAFFL" ctrl_grp <- "Placebo" -comp_btw_group <- TRUE -ancova <- TRUE +# Subgroup variable used for subgroup analyses. Set to NULL to suppress subgroup splits, +# or set to a character string with the variable name (e.g. "SEX", "AGEGR1"). +subgrpvar <- "AGEGR1" + +# Set to TRUE to include Interquartile range row in summary statistics blocks (default=TRUE) +show_iqr <- TRUE + +# Set to TRUE to include Total treatment (subject years) row (default=TRUE) +show_subj_years <- TRUE trtdur <- "TRTDURM" -daysconv <- 30.4375 -catlevels <- c( + +# Levels for AVALCAT7 (treatment duration categories, derived from PARAMCD=trtdur). +# Set as a character vector to control ordering of rows in the duration category table. +trtdurlevels <- c( "0 to <3 months", "3 to <6 months", "6 to <9 months", @@ -104,39 +93,65 @@ if (combined_colspan_trt == TRUE) { ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl), all_of(subgrpvar)) # If AVISIT is not present in ADEXSUM than create 'Overall' as the Visit, which is used # for the filtering AVISIT records if it does exist -adexsum <- adexsum_jnj %>% - mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") %>% - filter(PARAMCD == trtdur & !is.na(AVAL) & VISIT == "Overall") %>% +adexsum <- adexsum_jnj |> + mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") |> + filter((PARAMCD == trtdur | PARAMCD == "TRTDURD") & !is.na(AVAL) & VISIT == "Overall") |> mutate( CRIT0FL = "Y", CRIT0 = as.factor("Any duration (at least 1 dose)") - ) %>% - select(USUBJID, PARAMCD, AVAL, AVALCAT1, starts_with("CRIT")) + ) |> + select(USUBJID, PARAMCD, PARAM, AVAL, AVALCAT1, starts_with("CRIT")) |> + # Added AVAL_yr for subject years derivation from TRTDURD, /365.25 converts from days to years + mutate(AVAL_yr = ifelse(PARAMCD == "TRTDURD", AVAL / 365.25, NA), AVAL_anly = ifelse(PARAMCD == trtdur, AVAL, NA)) adexsum$CRIT0FL <- factor(adexsum$CRIT0FL, levels = c("Y", "N")) +# Extract unit from PARAM: captures content of first parentheses e.g. "Duration of Treatment (months)" -> "months" +# If unit is present in middle parentheses (not last), e.g. "Average daily dose ([unit]/day) (including days off treatment)" -> "[unit]/day" +unit_map <- adexsum |> + distinct(PARAMCD, PARAM) |> + filter(!is.na(PARAM)) |> + mutate( + unit = ifelse( + grepl("\\(.+\\)", PARAM), + gsub("^[^(]*\\(([^)]+)\\).*$", "\\1", PARAM), + "" + ) + ) |> + select(PARAMCD, unit) |> + tibble::deframe() + +get_unit <- function(paramcd) unit_map[[paramcd]] %||% "" + adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), levels = c("Active Study Agent", " ") ) -adsl$diff_header <- "Difference in Means (95% CI)" -adsl$diff_label <- paste(adsl[[trtvar]], paste("vs", ctrl_grp)) - # join data together -ex <- adexsum %>% inner_join(., adsl, by = c("USUBJID")) +ex <- adexsum |> inner_join(adsl, by = c("USUBJID")) # Keep only columns with some data in which will remove any unwanted CRITy variables ex <- ex[, colSums(is.na(ex)) < nrow(ex)] # Work out how many CRITy vars (ignoring CRIT0 we created) we have left -excritvars <- ex %>% +excritvars <- ex |> select(num_range("CRIT", 1:99)) countcritvars <- length(names(excritvars)) @@ -150,7 +165,7 @@ for (i in 1:countcritvars) { # drop unwanted levels from AVALCAT1 and assign levels from specified section at the top of script ex$AVALCAT1 <- droplevels(ex$AVALCAT1) -ex$AVALCAT1 <- factor(ex$AVALCAT1, levels = catlevels) +ex$AVALCAT1 <- factor(ex$AVALCAT1, levels = trtdurlevels) colspan_trt_map <- create_colspan_map( adsl, @@ -166,28 +181,39 @@ ref_path <- c("colspan_trt", "", trtvar, ctrl_grp) # Create label_map to be utilized in the Criterion variables (CRIT) ################################################################### -ex_lblmap <- ex %>% - select(-CRIT0, -CRIT0FL) %>% +ex_lblmap <- ex |> + select(-CRIT0, -CRIT0FL) |> + select(starts_with("CRIT")) |> tidyr::pivot_longer( cols = starts_with("CRIT") & ends_with("FL"), - names_to = "value", - values_to = "CF_value" - ) %>% - # Create the label by selecting the corresponding values from the CRIT columns - mutate( - label = case_when( - value == "CRIT1FL" ~ CRIT1, - value == "CRIT2FL" ~ CRIT2, - value == "CRIT3FL" ~ CRIT3, - value == "CRIT4FL" ~ CRIT4, - value == "CRIT5FL" ~ CRIT5, - value == "CRIT6FL" ~ CRIT6, - value == "CRIT7FL" ~ CRIT7 - ) - ) %>% - select(value, label) %>% - distinct() + names_to = "var", + values_to = "value" + ) |> + filter(value == "Y") |> + distinct() |> + tidyr::pivot_longer( + cols = starts_with("CRIT"), + names_to = "lbl_var", + values_to = "label" + ) |> + filter(var == paste0(lbl_var, "FL")) |> + select(var, value, label) |> + mutate(label = as.character(label)) |> + arrange(var) + +################################################################################ +# Formats for decimal precision control +################################################################################ +.stats_all <- c("mean_sd", "median", "range", "sum", "quantiles") +dp <- 1 +.formats_all <- junco:::fmt_spec_single_d( + d = dp, + stats_in = .stats_all, + fmt_d_def = junco_def_d_all, + fmt_d_in = NULL +) +fmt_details <- get_fmt_details(.formats_all, as_tibble = TRUE) ################################################################################ # Define layout and build table: @@ -195,49 +221,73 @@ ex_lblmap <- ex %>% extra_args_rr <- list(.stats = c("count_unique_fraction"), riskdiff = FALSE) +if (!is.null(subgrpvar)) { + extra_args_rr <- append(extra_args_rr, list(denom = c("n_df"), denom_by = c(subgrpvar))) +} + lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% - split_cols_by("diff_header", nested = FALSE) %>% - split_cols_by( - trtvar, - split_fun = remove_split_levels(ctrl_grp), - labels_var = "diff_label" - ) %>% +if (!is.null(subgrpvar)) { + lyt <- lyt |> + split_rows_by(subgrpvar, section_div = " ") |> + summarize_row_groups( + var = subgrpvar, + cfun = a_freq_j, + extra_args = list(.stats = "n_df", label_fstr = "Subgroup: %s") + ) +} + +lyt <- lyt |> analyze( - "AVAL", - afun = a_summarize_ex_j, - var_labels = "Duration of treatment~[super a], ([unit])", + "AVAL_anly", + afun = a_summary, + var_labels = sprintf("Duration of treatment~[super a], (%s)", get_unit(trtdur)), show_labels = "visible", indent_mod = 0L, extra_args = list( - daysconv = daysconv, ref_path = ref_path, - ancova = ancova, - comp_btw_group = comp_btw_group, - variables = list(arm = trtvar, covariates = NULL), - .formats = c( - range = jjcsformat_xx("xx.x, xx.x"), - "diff_mean_est_ci" = jjcsformat_xx("xx.xx (xx.xx, xx.xx)") - ) + .stats = c("mean_sd", "median", "range", if (show_iqr) "quantiles"), + .formats = .formats_all, + .labels = c(range = "Min, max", quantiles = "Interquartile range"), + .indent_mods = c("mean_sd" = 0L, "median" = 0L, "range" = 0L, "quantiles" = 0L) + ) + ) + +if (show_subj_years) { + lyt <- lyt |> + analyze( + "AVAL_yr", + afun = a_summary, + var_labels = sprintf("Duration of treatment~[super a], (%s)", get_unit(trtdur)), + show_labels = "hidden", + indent_mod = 1L, + extra_args = list( + ref_path = ref_path, + .stats = c("sum"), + .formats = .formats_all, + .labels = c(sum = "Total treatment (subject years)") + ), + section_div = " " ) - ) %>% +} + +lyt <- lyt |> analyze( "AVALCAT1", var_labels = "Duration of treatment, n (%)", @@ -245,43 +295,47 @@ lyt <- lyt %>% extra_args = extra_args_rr, indent_mod = 1L, show_labels = "visible", - nested = FALSE - ) %>% + section_div = " " + ) + +# Add in analyze for all CRIT variables contained in ex + +lyt <- lyt |> analyze( - paste0("CRIT", 1, "FL"), + "CRIT1FL", var_labels = "Duration of treatment~[super b], n (%)", afun = a_freq_j, extra_args = append( extra_args_rr, - list(label = as.character(ex_lblmap$label[1]), val = "Y") + list(label_map = ex_lblmap, val = "Y") ), indent_mod = 1L, - show_labels = "visible", - nested = FALSE + show_labels = "visible" ) -# Add in analyze for all others CRIT variables contained in ex -for (i in 2:countcritvars) { - lyt <- lyt %>% +if (countcritvars > 1) { + critvars <- paste0("CRIT", 2:countcritvars, "FL") + lyt <- lyt |> analyze( - paste0("CRIT", i, "FL"), + critvars, afun = a_freq_j, extra_args = append( extra_args_rr, - list(label = as.character(ex_lblmap$label[i]), val = "Y") + list(label_map = ex_lblmap, val = "Y") ), indent_mod = 2L, show_labels = "hidden" ) } -lyt <- lyt %>% +lyt <- lyt |> append_topleft("Parameter") -result <- build_table(lyt, ex, alt_counts_df = adsl) +result <- build_table(lyt, ex, alt_counts_df = adsl, round_type = "sas") -## Remove the N=xx column headers for the Difference (95% CI) columns -result <- remove_col_count(result, span_label_var = "diff_header") +if (!is.null(subgrpvar)) { + section_div_at_path(result, c("*", "@content", "n_df")) <- " " +} ################################################################################ # Add titles and footnotes: @@ -292,6 +346,7 @@ result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 27, 27, 27, 27, 35, 32) + +colwidth <- c(64, 34, 34, 34, 34) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsiex02.R b/tests/testthat/source_code/tsiex02.R index 1b4ea31f..651d9506 100644 --- a/tests/testthat/source_code/tsiex02.R +++ b/tests/testthat/source_code/tsiex02.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsiex02.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsiex02: Study Treatment Administration -## Author: Johnson & Johnson Innovative Medicine -## Date: 05 Feb 2024 -## Input: ADSL, ADEXSUM -## Output: TSIEX02.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -52,10 +28,69 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" +ctrl_grp <- "Placebo" + +# Set to TRUE to include difference in mean between treatment groups row (default=TRUE) +comp_btw_group <- TRUE + +# Set to TRUE to use ANCOVA approach for group comparison, FALSE for 2-sample t-test (default=TRUE) +ancova <- TRUE + +# Set to TRUE to include Interquartile range row in summary statistics blocks (default=TRUE) +show_iqr <- TRUE + +# Set to TRUE to include Total treatment (subject years) row (default=TRUE) +show_subj_years <- TRUE + +# Duration of treatment category +trtdur <- "TRTDURM" + +# Levels for AVAL1_C1 (treatment duration categories). Set as a character vector to control ordering. +trtdurlevels <- c( + "0 to <3 months", + "3 to <6 months", + "6 to <9 months", + "9 to <12 months", + "12 to <15 months", + "15 to <18 months", + "18 to <21 months", + "21 to <24 months", + "24 to <27 months", + "27 to <30 months", + "30 to <33 months", + "33 to <36 months", + "36 to <39 months" +) + +# Levels for (dosing days categories). Set to NULL to derive from data, +# or pre-define as a character vector to control ordering. +dsdyslevels_c1 <- c("1 to <30 days", "30 to <60 days", "60 to <90 days", ">=90 days") + +# Set to TRUE to include dosing days category (AVALCAT2 (renamed AVALCAT1 values of DOSEDAYS)) row (default=TRUE) +show_cat_dsdys <- TRUE + +# Levels for modal and final dose categories (AVALCAT6, AVALCAT7). Set as a character vector to control ordering. +mddlevels <- c("20 mg", "30 mg", "40 mg") -catlevels <- c("20 mg", "30 mg", "40 mg") +# Set to TRUE to include Average daily dose (including days off treatment) block (MEANDDI) (default=TRUE) +show_meanddi <- TRUE -combined_colspan_trt <- TRUE +# Set to TRUE to include Average daily dose (excluding days off treatment) block (MEANDD) (default=TRUE) +show_meandd <- TRUE + +# Set to TRUE to include Modal daily dose block (MODEDD) (default=TRUE) +show_modedd <- TRUE + +# Set to TRUE to include modal daily dose category (AVALCAT6 (renamed AVALCAT1 values of MODEDD)) row (default=TRUE) +show_cat_modedd <- TRUE + +# Set to TRUE to include Final daily dose block (FINDD) (default=TRUE) +show_findd <- TRUE + +# Set to TRUE to include final daily dose category (AVALCAT7 (renamed AVALCAT1 values of FINDD)) row (default=TRUE) +show_cat_findd <- TRUE + +combined_colspan_trt <- FALSE if (combined_colspan_trt == TRUE) { # Set up levels and label for the required combined columns @@ -81,58 +116,124 @@ if (combined_colspan_trt == TRUE) { ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(trtvar), all_of(popfl)) # If AVISIT is not present in ADEXSUM than create 'Overall' as the Visit, which is used # for the filtering AVISIT records if it does exist -adexsum <- adexsum_jnj %>% - mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") %>% +adexsum <- adexsum_jnj |> + mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") |> filter( PARAMCD %in% - c("DOSEDAYS", "CUMDOSE", "MEANDDI", "MEANDD", "MODEDD", "FINDD") & + c( + trtdur, + "TRTDURD", + "DOSEDAYS", + "CUMDOSE", + if (show_meanddi) "MEANDDI", + if (show_meandd) "MEANDD", + if (show_modedd) "MODEDD", + if (show_findd) "FINDD" + ) & !is.na(AVAL) & VISIT == "Overall" - ) %>% + ) |> mutate( - AVAL1 = case_when(PARAMCD == "DOSEDAYS" ~ AVAL), - AVAL2 = case_when(PARAMCD == "CUMDOSE" ~ AVAL), - AVAL3 = case_when(PARAMCD == "MEANDDI" ~ AVAL), - AVAL4 = case_when(PARAMCD == "MEANDD" ~ AVAL), - AVAL5 = case_when(PARAMCD == "MODEDD" ~ AVAL), - AVALCAT5 = case_when(PARAMCD == "MODEDD" ~ AVALCAT1), - AVAL6 = case_when(PARAMCD == "FINDD" ~ AVAL), - AVALCAT6 = case_when(PARAMCD == "FINDD" ~ AVALCAT1) - ) %>% + AVAL1 = case_when(PARAMCD == trtdur ~ AVAL), + AVAL1_C1 = case_when(PARAMCD == trtdur ~ AVALCAT1), + AVAL2 = case_when(PARAMCD == "DOSEDAYS" ~ AVAL), + AVALCAT2 = case_when(PARAMCD == "DOSEDAYS" ~ AVALCAT1), + AVAL3 = case_when(PARAMCD == "CUMDOSE" ~ AVAL), + AVAL4 = case_when(PARAMCD == "MEANDDI" ~ AVAL), + AVAL5 = case_when(PARAMCD == "MEANDD" ~ AVAL), + AVAL6 = case_when(PARAMCD == "MODEDD" ~ AVAL), + AVALCAT6 = case_when(PARAMCD == "MODEDD" ~ AVALCAT1), + AVAL7 = case_when(PARAMCD == "FINDD" ~ AVAL), + AVALCAT7 = case_when(PARAMCD == "FINDD" ~ AVALCAT1), + CRIT0FL = case_when(PARAMCD == trtdur ~ "Y"), + CRIT0 = case_when(PARAMCD == trtdur ~ as.factor("Any duration (at least 1 dose)")), + # Added AVAL_yr for subject years derivation from TRTDURD, /365.25 converts from days to years + AVAL_yr = case_when(PARAMCD == "TRTDURD" ~ AVAL / 365.25) + ) |> select( STUDYID, USUBJID, + PARAM, PARAMCD, AVAL1, AVAL2, + AVALCAT2, AVAL3, AVAL4, AVAL5, AVAL6, - AVALCAT5, - AVALCAT6 + AVAL7, + AVAL1_C1, + AVALCAT6, + AVALCAT7, + AVAL_yr, + starts_with("CRIT") ) +# Extract unit from PARAM: captures content of last parentheses e.g. "Duration of Treatment (months)" -> "months" +# If unit is present in middle parentheses (not last), e.g. "Average daily dose ([unit]/day) (including days off treatment)" -> "[unit]/day" +unit_map <- adexsum |> + distinct(PARAMCD, PARAM) |> + filter(!is.na(PARAM)) |> + mutate( + unit = ifelse( + grepl("\\(.+\\)", PARAM), + gsub("^[^(]*\\(([^)]+)\\).*$", "\\1", PARAM), + "" + ) + ) |> + select(PARAMCD, unit) |> + tibble::deframe() + +get_unit <- function(paramcd) unit_map[[paramcd]] %||% "" + adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), levels = c("Active Study Agent", " ") ) # join data together -ex <- adexsum %>% inner_join(., adsl, by = c("USUBJID")) +ex <- adexsum |> inner_join(adsl, by = c("USUBJID")) + +# Work out how many CRITy vars (ignoring CRIT0 we created) we have left +excritvars <- ex |> + select(num_range("CRIT", 1:99)) + +countcritvars <- length(names(excritvars)) + +# Drop unwanted levels for all CRITy variables you have remaining in ex and also for AVALCAT1 + +for (i in 1:countcritvars) { + variable_name <- paste0("CRIT", i) + ex[[variable_name]] <- droplevels(ex[[variable_name]]) +} # Drop unwanted levels for AVALCAT5 and AVALCAT6 and set levels defined in top section of script -ex$AVALCAT5 <- droplevels(ex$AVALCAT5) -ex$AVALCAT5 <- factor(ex$AVALCAT5, levels = catlevels) +ex$AVAL1_C1 <- droplevels(ex$AVAL1_C1) +ex$AVAL1_C1 <- factor(ex$AVAL1_C1, levels = trtdurlevels) +ex$AVALCAT2 <- droplevels(ex$AVALCAT2) +ex$AVALCAT2 <- factor(ex$AVALCAT2, levels = if (!is.null(dsdyslevels_c1)) dsdyslevels_c1 else levels(ex$AVALCAT2)) ex$AVALCAT6 <- droplevels(ex$AVALCAT6) -ex$AVALCAT6 <- factor(ex$AVALCAT6, levels = catlevels) +ex$AVALCAT6 <- factor(ex$AVALCAT6, levels = mddlevels) +ex$AVALCAT7 <- droplevels(ex$AVALCAT7) +ex$AVALCAT7 <- factor(ex$AVALCAT7, levels = mddlevels) colspan_trt_map <- create_colspan_map( adsl, @@ -143,250 +244,347 @@ colspan_trt_map <- create_colspan_map( trt_var = trtvar ) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +################################################################### +# Create label_map to be utilized in the Criterion variables (CRIT) +################################################################### + +ex_lblmap <- ex |> + select(-CRIT0, -CRIT0FL) |> + select(starts_with("CRIT")) |> + tidyr::pivot_longer( + cols = starts_with("CRIT") & ends_with("FL"), + names_to = "var", + values_to = "value" + ) |> + filter(value == "Y") |> + distinct() |> + tidyr::pivot_longer( + cols = starts_with("CRIT"), + names_to = "lbl_var", + values_to = "label" + ) |> + filter(var == paste0(lbl_var, "FL")) |> + select(var, value, label) |> + mutate(label = as.character(label)) |> + arrange(var) + ################################################################################ -# Define layout and build table: +# Formats for decimal precision control ################################################################################ -extra_args1 <- list( - .stats = "count_unique_fraction", - denom = "n_df" +.stats_all <- c("n", "mean_sd", "median", "range", "sum", "quantiles", "lsmean_diff_with_ci", "diff_means_est_ci") + +dp <- 1 +.formats_all <- junco:::fmt_spec_single_d( + d = dp, + stats_in = .stats_all, + fmt_d_def = junco_def_d_all, + fmt_d_in = NULL +) +fmt_details <- get_fmt_details(.formats_all, as_tibble = TRUE) + +# some parameters (Total dosing days, and daily dose) are reported in days or mg - these follow format rules with d = 0 +.formats_all0 <- junco:::fmt_spec_single_d( + d = 0, + stats_in = .stats_all, + fmt_d_def = junco_def_d_all, + fmt_d_in = NULL +) + +# labels +aval1_stats <- c("n", "mean_sd", "median", "range", if (show_iqr) "quantiles") + +aval1_labels <- c(n = "N", range = "Min, max", quantiles = "Interquartile range") +aval1_indent_mods <- c( + n = 0L, + mean_sd = 1L, + median = 1L, + range = 1L, + quantiles = 1L, + sum = 1L, + "lsmean_diff_with_ci" = 1L, + "diff_means_est_ci" = 1L ) +################################################################################ +# Define layout and build table: +################################################################################ +extra_args_rr <- list(.stats = c("count_unique_fraction"), riskdiff = FALSE) lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> analyze( "AVAL1", - table_names = "AVAL1x", - var_labels = "Total dosing days of treatment (excluding days off treatment)~[super a]", + afun = a_summary, + var_labels = sprintf("Duration of treatment~[super a], (%s)", get_unit(trtdur)), show_labels = "visible", indent_mod = 0L, - afun = function(x) { - list( - "N" = rcell(length(x), format = jjcsformat_xx("xx")) + extra_args = list( + ref_path = ref_path, + .stats = aval1_stats, + .formats = .formats_all, + .labels = aval1_labels, + .indent_mods = aval1_indent_mods + ) + ) + +if (show_subj_years) { + lyt <- lyt |> + analyze( + "AVAL_yr", + afun = a_summary, + var_labels = sprintf("Duration of treatment~[super a], (%s)", get_unit(trtdur)), + show_labels = "hidden", + indent_mod = 2L, + extra_args = list( + ref_path = ref_path, + .stats = c("sum"), + .formats = .formats_all, + .labels = c(sum = "Total treatment (subject years)") ) - } - ) %>% - analyze( - "AVAL1", - nested = TRUE, - var_labels = "Total dosing days of treatment (excluding days off treatment)~[super a]", - show_labels = "hidden", - indent_mod = 2L, - afun = function(x) { - list( - "Mean (SD)" = rcell( - c(mean(x), sd(x)), - format = jjcsformat_xx("xx.x (xx.xx)") + ) +} + +lyt <- lyt + +if (comp_btw_group) { + diff_lbl <- "Difference in means [Study Treatment] vs. [Placebo] (95% CI)" + diff_fmt <- jjcsformat_xx("xx.xx (xx.xx, xx.xx)") + if (ancova) { + message("difference between groups using ancova approach") + lyt <- lyt |> + analyze( + vars = "AVAL1", + table_names = "AVAL_diff", + afun = a_summarize_ancova_j, + show_labels = "hidden", + indent_mod = 2L, + extra_args = list( + ref_path = ref_path, + variables = list(arm = trtvar, covariates = NULL), + conf_level = 0.95, + weights_combo = "proportional", + .stats = "lsmean_diff_with_ci", + .formats = .formats_all, + .labels = c(lsmean_diff_with_ci = diff_lbl) ), - "Median" = rcell(median(x), format = jjcsformat_xx("xx.x")), - "Min, max" = rcell( - c(min(x), max(x)), - format = jjcsformat_xx("xx., xx.") + section_div = " " + ) + } else { + message("difference between groups using 2 sample t-test approach") + lyt <- lyt |> + analyze( + vars = "AVAL1", + table_names = "AVAL_diff_desc", + afun = a_diff_means, + show_labels = "hidden", + indent_mod = 2L, + extra_args = list( + ref_path = ref_path, + conf_level = 0.95, + .stats = "diff_means_est_ci", + .formats = .formats_all, + .labels = c(diff_means_est_ci = diff_lbl) ), - "Interquartile range" = rcell( - c(quantile(x, c(0.25, 0.75), type = 2)), - format = jjcsformat_xx("xx.x, xx.x") - ) + section_div = " " ) - } - ) %>% + } +} + +lyt <- lyt |> analyze( - "AVAL2", - table_names = "AVAL2x", - nested = FALSE, - var_labels = "Cumulative dose ([unit])", + "AVAL1_C1", + var_labels = "Duration of treatment, n (%)", + afun = a_freq_j, + extra_args = extra_args_rr, + indent_mod = 2L, show_labels = "visible", - indent_mod = 0L, - afun = function(x) { - list( - "N" = rcell(length(x), format = jjcsformat_xx("xx")) - ) - } - ) %>% - analyze( - "AVAL2", nested = TRUE, - var_labels = "Cumulative dose ([unit])", - show_labels = "hidden", + section_div = " " + ) |> + analyze( + paste0("CRIT", 1, "FL"), + var_labels = "Duration of treatment~[super b], n (%)", + afun = a_freq_j, + extra_args = append( + extra_args_rr, + list(label = as.character(ex_lblmap$label[1]), val = "Y") + ), indent_mod = 2L, - afun = function(x) { - list( - "Mean (SD)" = rcell( - c(mean(x), sd(x)), - format = jjcsformat_xx("xx.x (xx.xx)") - ), - "Median" = rcell(median(x), format = jjcsformat_xx("xx.x")), - "Min, max" = rcell( - c(min(x), max(x)), - format = jjcsformat_xx("xx., xx.") - ), - "Interquartile range" = rcell( - c(quantile(x, c(0.25, 0.75), type = 2)), - format = jjcsformat_xx("xx.x, xx.x") - ) - ) - } - ) %>% + show_labels = "visible", + nested = TRUE + ) + +# Add in analyze for all others CRIT variables contained in ex +if (countcritvars > 1) { + critvars <- paste0("CRIT", 2:countcritvars, "FL") + lyt <- lyt |> + analyze( + critvars, + afun = a_freq_j, + extra_args = append( + extra_args_rr, + list(label_map = ex_lblmap, val = "Y") + ), + indent_mod = 3L, + show_labels = "hidden" + ) +} + +lyt <- lyt |> analyze( - "AVAL3", - table_names = "AVAL3x", + "AVAL2", nested = FALSE, - var_labels = "Average daily dose ([unit/day]) (including days off treatment)", + var_labels = "Total dosing days of treatment (excluding days off treatment)~[super c]", show_labels = "visible", - indent_mod = 0L, - afun = function(x) { - list( - "N" = rcell(length(x), format = jjcsformat_xx("xx")) - ) - } - ) %>% + afun = a_summary, + extra_args = list( + .stats = aval1_stats, + .formats = .formats_all0, + .labels = aval1_labels, + .indent_mods = aval1_indent_mods + ) + ) +if (show_cat_dsdys && any(!is.na(ex$AVALCAT2))) { + lyt <- lyt |> + analyze( + "AVALCAT2", + afun = a_freq_j, + extra_args = extra_args_rr, + show_labels = "hidden", + indent_mod = 2L + ) +} +lyt <- lyt |> analyze( "AVAL3", - nested = TRUE, - var_labels = "Average daily dose ([unit/day]) (including days off treatment)", - show_labels = "hidden", - indent_mod = 2L, - afun = function(x) { - list( - "Mean (SD)" = rcell( - c(mean(x), sd(x)), - format = jjcsformat_xx("xx.xx (xx.xxx)") - ), - "Median" = rcell(median(x), format = jjcsformat_xx("xx.xx")), - "Min, max" = rcell( - c(min(x), max(x)), - format = jjcsformat_xx("xx.x, xx.x") - ), - "Interquartile range" = rcell( - c(quantile(x, c(0.25, 0.75), type = 2)), - format = jjcsformat_xx("xx.xx, xx.xx") - ) - ) - } - ) %>% - analyze( - "AVAL4", - table_names = "AVAL4x", nested = FALSE, - var_labels = "Average daily dose ([unit/day]) (excluding days off treatment)", + var_labels = sprintf("Cumulative dose (%s)", get_unit("CUMDOSE")), show_labels = "visible", - indent_mod = 0L, - afun = function(x) { - list( - "N" = rcell(length(x), format = jjcsformat_xx("xx")) - ) - } - ) %>% - analyze( - "AVAL4", - nested = TRUE, - var_labels = "Average daily dose ([unit/day]) (excluding days off treatment)", - show_labels = "hidden", - indent_mod = 2L, - afun = function(x) { - list( - "Mean (SD)" = rcell( - c(mean(x), sd(x)), - format = jjcsformat_xx("xx.xx (xx.xxx)") - ), - "Median" = rcell(median(x), format = jjcsformat_xx("xx.xx")), - "Min, max" = rcell( - c(min(x), max(x)), - format = jjcsformat_xx("xx.x, xx.x") - ), - "Interquartile range" = rcell( - c(quantile(x, c(0.25, 0.75), type = 2)), - format = jjcsformat_xx("xx.xx, xx.xx") - ) + afun = a_summary, + extra_args = list( + .stats = aval1_stats, + .formats = .formats_all0, + .labels = aval1_labels, + .indent_mods = aval1_indent_mods + ) + ) + +if (show_meanddi) { + lyt <- lyt |> + analyze( + "AVAL4", + nested = FALSE, + var_labels = sprintf("Average daily dose (%s) (including days off treatment)", get_unit("MEANDDI")), + show_labels = "visible", + afun = a_summary, + extra_args = list( + .stats = aval1_stats, + .formats = .formats_all, + .labels = aval1_labels, + .indent_mods = aval1_indent_mods ) - } - ) %>% - analyze( - "AVAL5", - nested = FALSE, - var_labels = "Modal daily dose ([unit/day]), n (%)", - show_labels = "visible", - indent_mod = 0L, - afun = function(x) { - list( - "N" = rcell(length(x), format = jjcsformat_xx("xx")) + ) +} + +if (show_meandd) { + lyt <- lyt |> + analyze( + "AVAL5", + nested = FALSE, + var_labels = sprintf("Average daily dose (%s) (excluding days off treatment)", get_unit("MEANDD")), + show_labels = "visible", + afun = a_summary, + extra_args = list( + .stats = aval1_stats, + .formats = .formats_all, + .labels = aval1_labels, + .indent_mods = aval1_indent_mods ) - } - ) %>% - analyze( - "AVALCAT5", - afun = a_freq_j, - extra_args = extra_args1, - show_labels = "hidden", - indent_mod = 2L - ) %>% - analyze( - "AVAL6", - table_names = "AVAL6x", - nested = FALSE, - var_labels = "Final daily dose ([unit/day])", - show_labels = "visible", - indent_mod = 0L, - afun = function(x) { - list( - "N" = rcell(length(x), format = jjcsformat_xx("xx")) + ) +} + +if (show_modedd) { + lyt <- lyt |> + analyze( + "AVAL6", + nested = FALSE, + var_labels = sprintf("Modal daily dose (%s), n (%%)", get_unit("MODEDD")), + show_labels = "visible", + afun = a_summary, + extra_args = list( + .stats = c("n"), + .formats = .formats_all0, + .labels = aval1_labels, + .indent_mods = aval1_indent_mods ) - } - ) %>% - analyze( - "AVAL6", - nested = TRUE, - var_labels = "Final daily dose ([unit/day])", - show_labels = "hidden", - indent_mod = 2L, - afun = function(x) { - list( - "Mean (SD)" = rcell( - c(mean(x), sd(x)), - format = jjcsformat_xx("xx.x (xx.xx)") - ), - "Median" = rcell(median(x), format = jjcsformat_xx("xx.x")), - "Min, max" = rcell( - c(min(x), max(x)), - format = jjcsformat_xx("xx., xx.") - ), - "Interquartile range" = rcell( - c(quantile(x, c(0.25, 0.75), type = 2)), - format = jjcsformat_xx("xx.x, xx.x") - ) + ) +} + +if (show_modedd && show_cat_modedd && any(!is.na(ex$AVALCAT6))) { + lyt <- lyt |> + analyze( + "AVALCAT6", + afun = a_freq_j, + extra_args = extra_args_rr, + show_labels = "hidden", + indent_mod = 2L + ) +} + +if (show_findd) { + lyt <- lyt |> + analyze( + "AVAL7", + nested = FALSE, + var_labels = sprintf("Final daily dose (%s)", get_unit("FINDD")), + show_labels = "visible", + afun = a_summary, + extra_args = list( + .stats = aval1_stats, + .formats = .formats_all0, + .labels = aval1_labels, + .indent_mods = aval1_indent_mods ) - } - ) %>% - analyze( - "AVALCAT6", - afun = a_freq_j, - nested = FALSE, - show_labels = "visible", - var_labels = "Final daily dose ([unit/day]), n (%)", - extra_args = extra_args1, - indent_mod = 1L - ) %>% + ) +} + +if (show_findd && show_cat_findd && any(!is.na(ex$AVALCAT7))) { + lyt <- lyt |> + analyze( + "AVALCAT7", + afun = a_freq_j, + nested = FALSE, + show_labels = "visible", + var_labels = sprintf("Final daily dose (%s), n (%%)", get_unit("FINDD")), + extra_args = extra_args_rr, + indent_mod = 2L + ) +} + +lyt <- lyt |> append_topleft("Parameter") -result <- build_table(lyt, ex, alt_counts_df = adsl) +result <- build_table(lyt, ex, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Add titles and footnotes: @@ -397,6 +595,7 @@ result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 31, 31, 31, 31) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") +colwidth <- c(64, 34, 35, 31) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, label_width_ins = 2.4, orientation = "portrait") diff --git a/tests/testthat/source_code/tsiex02b.R b/tests/testthat/source_code/tsiex02b.R new file mode 100644 index 00000000..1638da01 --- /dev/null +++ b/tests/testthat/source_code/tsiex02b.R @@ -0,0 +1,370 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +# - Define how to create combined treatment columns (if required) +################################################################################ + +tblid <- "TSIEX02b" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +trtvar <- "TRT01A" +popfl <- "SAFFL" +combined_colspan_trt <- TRUE +ctrl_grp <- "Placebo" + +# dose_dly will be TRUE if study collected dose delay by default it is FALSE +dose_dly <- TRUE + +# trt_period will be TRUE if APERIOD details available by default it is FALSE +trt_period <- TRUE + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +################################################################################ +# Process Data: +################################################################################ + +# Read in required data +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +core_ex_vars <- c( + "USUBJID", + "AACTPR", + "AACTDU", + "AADJ", + "AADJP", + "AVISIT", + "AVISITN" +) + +# Conditionally include dose delay variables if dose_dly is TRUE +dose_dly_vars <- if (isTRUE(dose_dly)) c("ADOSDLY", "ARSDOSD") else NULL + +# Conditionally include treatment period variables if trt_period is TRUE +period_vars <- if (isTRUE(trt_period)) c("APERIOD", "APERIODC") else NULL + +# Read input data, exclude unscheduled visits, select required variables +adex1 <- adex_jnj |> + filter(!grepl("UNSCHEDULED", AVISIT, ignore.case = TRUE)) |> + select(all_of(core_ex_vars), all_of(dose_dly_vars), all_of(period_vars)) + +# Convert AVISIT to sentence case and apply levels to maintain ordering +avisit_levs <- adex1 |> + distinct(AVISIT, AVISITN) |> + arrange(AVISITN) |> + pull(AVISIT) |> + stringr::str_to_sentence() +adex1$AVISIT <- stringr::str_to_sentence(adex1$AVISIT) +adex1$AVISIT <- factor(adex1$AVISIT, levels = avisit_levs) + +# action taken to prescribed dose compared to prior +adex1a <- adex1 |> + mutate( + AACTx = AACTPR, + AADJx = AADJP, + XXX = "Action taken to prescribed dose compared to prior" + ) +# action taken with study treatment +adex1b <- adex1 |> + mutate( + AACTx = AACTDU, + AADJx = AADJ, + XXX = "Action taken with study treatment" + ) +# Dose delay data based on dose_dly +if (isTRUE(dose_dly)) { + adex1c <- adex1 |> + filter(ADOSDLY == "Y") |> + mutate( + AACTx = ADOSDLY, + AADJx = ARSDOSD, + XXX = "Dose delay" + ) + adex_all <- bind_rows(adex1a, adex1b, adex1c) +} else { + adex_all <- bind_rows(adex1a, adex1b) +} +# Any action taken or dose delay of study treatment +any_label <- if (isTRUE(dose_dly)) { + "Any action taken or dose delay of study treatment~[super a]" +} else { + "Any action taken of study treatment~[super a]" +} +adex_any <- adex_all |> mutate(ANY = any_label) +# Stack all data +adex <- bind_rows(adex_any, adex_all) + +# Adding factor level for categories +adex$ANY <- factor(adex$ANY, levels = unique(adex$ANY)) + +# Convert ARSDOSD to sentence case +if (isTRUE(dose_dly)) { + adex$ARSDOSD <- factor( + stringr::str_to_sentence(as.character(adex$ARSDOSD)), + levels = stringr::str_to_sentence(levels(adex$ARSDOSD)) + ) +} + +# Re-apply APERIOD/APERIODC factor levels after bind_rows (bind drops levels) +if (isTRUE(trt_period)) { + adex$APERIOD <- factor(adex$APERIOD, levels = c("1", "2")) + adex$APERIODC <- factor(adex$APERIODC, levels = c("Period 1", "Period 2")) +} + +xxx_levels <- c( + "Action taken to prescribed dose compared to prior", + "Dose delay", + "Action taken with study treatment" +) + +# control levels of new variables AACTx and AADJx +aact_levels <- c( + "DOSE REDUCED COMPARED TO PRIOR INFUSION", + "INFUSION DELAYED WITHIN THE CYCLE", + "INFUSION RATE DECREASED COMPARED TO PRIOR INFUSION", + "INFUSION SKIPPED (AND NOT MADE UP)", + "STUDY DRUG PERMANENTLY DISCONTINUED", + "INFUSION ABORTED", + "INFUSION INTERRUPTED", + "INFUSION RATE INCREASED" +) + +aact_labels <- c( + "Dose reduced", + "Infusion delayed", + "Infusion rate decreased", + "Infusion skipped", + "Study agent permanently discontinued", + "Infusion aborted", + "Infusion interrupted", + "Infusion rate increased" +) + +adex$AACTx <- factor( + as.character(adex$AACTx), + levels = aact_levels, + labels = aact_labels +) + +adex$AADJx <- factor( + stringr::str_to_sentence(as.character(adex$AADJx)), + levels = stringr::str_to_sentence(levels(c(adex$AADJ, adex$AADJP))) +) + +### Note the following levels are not used on the table, not sure if this is OK --- +### this is out of scope for template script +### how standard is this table and the levels of the variables on the current dataset + standard ADaM??? +setdiff(levels(adex$AACTPR), aact_levels) +setdiff(levels(adex$AACTDU), aact_levels) + +# join adsl data with population subset +ex <- adex |> inner_join(adsl, by = c("USUBJID")) + +################################################################################ +# Define layout and build table: +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +# extra_args1: frequency args for treatment period analysis (denominator by APERIOD) +extra_args1 <- list( + .stats = "count_unique_fraction", + denom = "n_parentdf", + denom_by = "APERIOD", + drop_levels = TRUE +) +# extra_args2: frequency args for time point analysis (denominator by AVISIT) +extra_args2 <- list( + .stats = "count_unique_fraction", + denom = "n_parentdf", + denom_by = "AVISIT", + drop_levels = TRUE +) + +# --- Column structure --- +lyt0 <- rtables::basic_table( + top_level_section_div = " ", + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt0 |> split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt0 |> split_cols_by(trtvar) +} + +# --- Section 1: Overall summary (ANY) --- +lyt <- lyt |> + split_rows_by( + "ANY", + split_label = "Time Point", + split_fun = drop_split_levels, + label_pos = "topleft", + child_labels = "hidden", + indent_mod = 0L, + section_div = " " + ) |> + summarize_row_groups("ANY", cfun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) |> + split_rows_by("AACTx", split_fun = drop_split_levels, section_div = " ") |> + summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) |> + analyze("AADJx", afun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) +if (isTRUE(dose_dly)) { + lyt <- lyt |> + split_rows_by("XXX", split_fun = keep_split_levels(c("Dose delay")), indent_mod = 1L) |> + summarize_row_groups("XXX", cfun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) |> + analyze("ARSDOSD", afun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) +} +# --- Section 2: Treatment Period breakdown (only when trt_period = TRUE) --- +if (isTRUE(trt_period)) { + lyt <- lyt |> + split_rows_by( + "APERIOD", + labels_var = "APERIODC", + split_fun = keep_split_levels(c("1", "2")), + child_labels = "visible", + indent_mod = 0L, + section_div = " " + ) + if (isTRUE(dose_dly)) { + lyt <- lyt |> + split_rows_by("XXX", split_fun = keep_split_levels(xxx_levels), section_div = " ") |> + split_rows_by("AACTx", split_fun = drop_split_levels, section_div = " ") |> + summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = extra_args1) |> + analyze("AADJx", afun = a_freq_j, extra_args = extra_args1) + } else { + lyt <- lyt |> + split_rows_by( + "XXX", + split_fun = keep_split_levels(c( + "Action taken to prescribed dose compared to prior", + "Action taken with study treatment" + )), + section_div = " " + ) |> + split_rows_by("AACTx", split_fun = drop_split_levels, section_div = " ") |> + summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = extra_args1) |> + analyze("AADJx", afun = a_freq_j, extra_args = extra_args1) + } +} + +# --- Section 3: Time Point (AVISIT) breakdown --- +lyt <- lyt |> + split_rows_by( + "AVISIT", + split_fun = drop_split_levels, + child_labels = "visible", + indent_mod = 0L, + section_div = " " + ) +if (isTRUE(dose_dly)) { + lyt <- lyt |> + split_rows_by("XXX", split_fun = keep_split_levels(xxx_levels), section_div = " ") |> + summarize_row_groups("XXX", cfun = a_freq_j, extra_args = list(.stats = "n_df")) |> + split_rows_by("AACTx", split_fun = drop_split_levels, section_div = " ") |> + summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = extra_args2) |> + analyze("AADJx", afun = a_freq_j, extra_args = extra_args2) |> + append_topleft(" Action Taken or Dose Delay") |> + append_topleft(" Reason, n (%)") +} else { + lyt <- lyt |> + split_rows_by( + "XXX", + split_fun = keep_split_levels(c( + "Action taken to prescribed dose compared to prior", + "Action taken with study treatment" + )), + section_div = " " + ) |> + summarize_row_groups("XXX", cfun = a_freq_j, extra_args = list(.stats = "n_df")) |> + split_rows_by("AACTx", split_fun = drop_split_levels, section_div = " ") |> + summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = extra_args2) |> + analyze("AADJx", afun = a_freq_j, extra_args = extra_args2) |> + append_topleft(" Action Taken") |> + append_topleft(" Reason, n (%)") +} + +result <- build_table(lyt, ex, alt_counts_df = adsl, round_type = "sas") +################################################################################ +# Prune table to remove all the rows with 0 counts or no data to report across all sections +################################################################################ + +result <- prune_table(result, prune_func = prune_zeros_only) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + +colwidth <- c(64, 23, 23, 25, 23) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, label_width_ins = 2.4, orientation = "portrait") diff --git a/tests/testthat/source_code/tsiex03.R b/tests/testthat/source_code/tsiex03.R index e22ba9ff..fdb60f4e 100644 --- a/tests/testthat/source_code/tsiex03.R +++ b/tests/testthat/source_code/tsiex03.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsiex03.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsiex03: Study Treatment Administration -## Author: Johnson & Johnson Innovative Medicine -## Date: 05 Feb 2024 -## Input: ADSL, ADEXSUM -## Output: TSIEX03.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -36,7 +12,21 @@ library(junco) # - Define output ID and file location # - Define treatment variable used (default=TRT01A) # - Define population flag used (default=SAFFL) -# - Define levels which will control ordering for AVALCAT1 in the table +# - Define levels which will control ordering for AVALCAT2 (total number of administrations categories) +# in the table. Set as a character vector to control ordering. +# - Set to TRUE to include Total Number of Administrations section (default=TRUE) +# - Set to TRUE to include AVALCAT2 (total number of administrations categories) rows (default=TRUE) +# - Set to TRUE to include CRIT variables for total number of administrations (default=TRUE) +# - Define control group (default=Placebo) +# - Set to TRUE to include difference in mean between treatment groups row (default=TRUE) +# - Set to TRUE to use ANCOVA approach for group comparison, FALSE for 2-sample t-test (default=TRUE) +# - Set to TRUE to include Interquartile range row in summary statistics blocks (default=TRUE) +# - Set to TRUE to include Total treatment (subject years) row (default=TRUE) +# - Define parameter code needed for duration of treatment +# - Conversion to get the unit of PARAMCD selected for treatment +# (i.e 1 if original PARAMCD unit is days, 30.4375 if original PARAMCD unit is in months) +# - Define levels which will control ordering for AVALCAT1 (duration of treatment categories) +# in the table. Set as a character vector to control ordering. # - Choose whether or not you want to present a combined active treatment column (default=TRUE) # - Define how to create combined treatment columns (if required) ################################################################################ @@ -53,7 +43,47 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" -catlevels <- c("1 to <10", "10 to <20", ">=20") +# Levels for AVALCAT2 (total number of administrations categories). Set as a character vector to control ordering. +totadminlevels <- c("1 to <10", "10 to <20", ">=20") + +# Set to TRUE to include Total Number of Administrations section (default=TRUE) +show_totadmin <- TRUE +# Set to TRUE to include AVALCAT2 (total number of administrations categories) rows (default=TRUE) +show_totadmin_avalcat <- TRUE +# Set to TRUE to include CRIT variables for total number of administrations (default=TRUE) +show_totadmin_crit <- TRUE + +ctrl_grp <- "Placebo" + +# Set to TRUE to include difference in mean between treatment groups row (default=TRUE) +comp_btw_group <- TRUE +# Set to TRUE to use ANCOVA approach for group comparison, FALSE for 2-sample t-test (default=TRUE) +ancova <- TRUE + +# Set to TRUE to include Interquartile range row in summary statistics blocks (default=TRUE) +show_iqr <- TRUE + +# Set to TRUE to include Total treatment (subject years) row (default=TRUE) +show_subj_years <- TRUE + +trtdur <- "TRTDURM" + +# Levels for AVALCAT1 (duration of treatment categories). Set as a character vector to control ordering. +trtdurlevels <- c( + "0 to <3 months", + "3 to <6 months", + "6 to <9 months", + "9 to <12 months", + "12 to <15 months", + "15 to <18 months", + "18 to <21 months", + "21 to <24 months", + "24 to <27 months", + "27 to <30 months", + "30 to <33 months", + "33 to <36 months", + "36 to <39 months" +) combined_colspan_trt <- TRUE @@ -81,26 +111,69 @@ if (combined_colspan_trt == TRUE) { ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> select(USUBJID, all_of(trtvar), all_of(popfl)) # If AVISIT is not present in ADEXSUM than create 'Overall' as the Visit, which is used # for the filtering AVISIT records if it does exist -adexsum1 <- adexsum_jnj %>% - mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") %>% - filter(PARAMCD == "TNUMDOS" & !is.na(AVAL) & VISIT == "Overall") %>% - mutate(AVAL1 = AVAL) %>% - select(STUDYID, USUBJID, PARAMCD, AVAL1, AVALCAT1, starts_with("CRIT")) - -adexsum2 <- adexsum_jnj %>% - mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") %>% - filter(PARAMCD == "CUMDOSE" & !is.na(AVAL) & VISIT == "Overall") %>% - mutate(AVAL2 = AVAL) %>% - select(STUDYID, USUBJID, PARAMCD, AVAL2) +# Duration of treatment parameter +adexsum1 <- adexsum_jnj |> + mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") |> + filter((PARAMCD == trtdur | PARAMCD == "TRTDURD") & !is.na(AVAL) & VISIT == "Overall") |> + mutate( + AVAL1 = ifelse(PARAMCD == trtdur, AVAL, NA), + # Added AVAL_yr for subject years derivation from TRTDURD, /365.25 converts from days to years + AVAL_yr = ifelse(PARAMCD == "TRTDURD", AVAL / 365.25, NA), + CRIT0FL = "Y", + CRIT0 = as.factor("Any duration (at least 1 dose)") + ) |> + select(STUDYID, USUBJID, PARAMCD, PARAM, AVAL1, AVAL_yr, AVALCAT1, starts_with("CRIT")) + +# Total Number of Administrations +adexsum2 <- adexsum_jnj |> + mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") |> + filter(PARAMCD == "TNUMDOS" & !is.na(AVAL) & VISIT == "Overall") |> + mutate(AVAL2 = AVAL, AVALCAT2 = AVALCAT1) |> + select(STUDYID, USUBJID, PARAMCD, PARAM, AVAL2, AVALCAT2, starts_with("CRIT")) |> + rename_with(~ paste0(., "_NDOS"), starts_with("CRIT")) + +# Cumulative dose +adexsum3 <- adexsum_jnj |> + mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") |> + filter(PARAMCD == "CUMDOSE" & !is.na(AVAL) & VISIT == "Overall") |> + mutate(AVAL3 = AVAL) |> + select(STUDYID, USUBJID, PARAMCD, PARAM, AVAL3) + +adexsum <- bind_rows(adexsum1, adexsum2, adexsum3) |> + select(STUDYID, USUBJID, PARAMCD, PARAM, AVAL1, AVAL2, AVAL3, AVAL_yr, AVALCAT1, AVALCAT2, starts_with("CRIT")) + +# Extract unit from PARAM: captures content of first parentheses e.g. "Duration of Treatment (months)" -> "months" +# If unit is present in middle parentheses (not last), e.g. "Average daily dose ([unit]/day) (including days off treatment)" -> "[unit]/day" +unit_map <- adexsum |> + distinct(PARAMCD, PARAM) |> + filter(!is.na(PARAM)) |> + mutate( + unit = ifelse( + grepl("\\(.+\\)", PARAM), + gsub("^[^(]*\\(([^)]+)\\).*$", "\\1", PARAM), + "" + ) + ) |> + select(PARAMCD, unit) |> + tibble::deframe() -adexsum <- bind_rows(adexsum1, adexsum2) %>% - select(STUDYID, USUBJID, PARAMCD, AVAL1, AVAL2, AVALCAT1, starts_with("CRIT")) +get_unit <- function(paramcd) unit_map[[paramcd]] %||% "" adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -108,22 +181,35 @@ adsl$colspan_trt <- factor( ) # join data together -ex <- adexsum %>% inner_join(., adsl, by = c("USUBJID")) +ex <- adexsum |> inner_join(adsl, by = c("USUBJID")) # Keep only columns with some data in which will remove any unwanted CRITy variables ex <- ex[, colSums(is.na(ex)) < nrow(ex)] # Work out how many CRITy vars we have left -excritvars <- ex %>% +excritvars <- ex |> select(num_range("CRIT", 1:99)) countcritvars <- length(names(excritvars)) -# Drop unwanted levels for all CRITy variables you have remaining in ex and also for AVALCAT1 +for (i in 1:countcritvars) { + variable_name <- paste0("CRIT", i, "FL") + ex[[variable_name]] <- droplevels(ex[[variable_name]]) +} + +# drop unwanted levels from AVALCAT1 and assign levels from specified section at the top of script +ex$AVALCAT1 <- droplevels(ex$AVALCAT1) +ex$AVALCAT1 <- factor(ex$AVALCAT1, levels = trtdurlevels) + +# Drop unwanted levels for all CRITy variables you have remaining in ex and also for AVALCAT2 +ex2critvars <- ex |> + select(num_range("CRIT", 1:99, suffix = "_NDOS")) + +count2critvars <- length(names(ex2critvars)) critlbls <- list() -for (i in 1:countcritvars) { - variable_name <- paste0("CRIT", i) +for (i in 1:count2critvars) { + variable_name <- paste0("CRIT", i, "_NDOS") ex[[variable_name]] <- droplevels(ex[[variable_name]]) critlbls[[i]] <- unique(as.character(ex[[variable_name]][ !is.na(ex[[variable_name]]) @@ -131,8 +217,8 @@ for (i in 1:countcritvars) { } # drop unwanted levels from AVALCAT1 and assign levels from specified section at the top of script -ex$AVALCAT1 <- droplevels(ex$AVALCAT1) -ex$AVALCAT1 <- factor(ex$AVALCAT1, levels = catlevels) +ex$AVALCAT2 <- droplevels(ex$AVALCAT2) +ex$AVALCAT2 <- factor(ex$AVALCAT2, levels = totadminlevels) colspan_trt_map <- create_colspan_map( adsl, @@ -143,154 +229,300 @@ colspan_trt_map <- create_colspan_map( trt_var = trtvar ) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +################################################################### +# Create label_map to be utilized in the Criterion variables (CRIT) +# This is needed as the CRIT variables are not labeled in the dataset +# for Duration of Treatment (TRTDURM) parameter +################################################################### + +ex_lblmap <- ex |> + select(-CRIT0, -CRIT0FL) |> + select(starts_with("CRIT")) |> + tidyr::pivot_longer( + cols = starts_with("CRIT") & ends_with("FL"), + names_to = "var", + values_to = "value" + ) |> + filter(value == "Y") |> + distinct() |> + tidyr::pivot_longer( + cols = starts_with("CRIT"), + names_to = "lbl_var", + values_to = "label" + ) |> + filter(var == paste0(lbl_var, "FL")) |> + select(var, value, label) |> + mutate(label = as.character(label)) |> + arrange(var) + ################################################################################ -# Define layout and build table: +# Formats for decimal precision control ################################################################################ -extra_args1 <- list( - .stats = "count_unique_fraction", - denom = "n_df" +.stats_all <- c("n", "mean_sd", "median", "range", "sum", "quantiles", "lsmean_diff_with_ci", "diff_means_est_ci") + +dp <- 1 +.formats_all <- junco:::fmt_spec_single_d( + d = dp, + stats_in = .stats_all, + fmt_d_def = junco_def_d_all, + fmt_d_in = NULL +) +fmt_details <- get_fmt_details(.formats_all, as_tibble = TRUE) + +# some parameters (Total dosing days, and daily dose) are reported in days or mg - these follow format rules with d = 0 +.formats_all0 <- junco:::fmt_spec_single_d( + d = 0, + stats_in = .stats_all, + fmt_d_def = junco_def_d_all, + fmt_d_in = NULL ) -extra_args2 <- list( - denom = "n_df", - .stats = "count_unique_fraction" +# labels +aval1_stats <- c("n", "mean_sd", "median", "range", if (show_iqr) "quantiles") + +aval1_labels <- c(n = "N", range = "Min, max", quantiles = "Interquartile range") +aval1_indent_mods <- c( + n = 0L, + mean_sd = 1L, + median = 1L, + range = 1L, + quantiles = 1L, + sum = 1L, + "lsmean_diff_with_ci" = 1L, + "diff_means_est_ci" = 1L ) +################################################################################ +# Define layout and build table: +################################################################################ + +extra_args_rr <- list(.stats = c("count_unique_fraction"), riskdiff = FALSE) + lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +# Duration of Treatment +lyt <- lyt |> analyze( "AVAL1", - table_names = "AVAL1x", - var_labels = "Total number of administrations", + afun = a_summary, + var_labels = sprintf("Duration of treatment~[super a], (%s)", get_unit(trtdur)), show_labels = "visible", indent_mod = 0L, - afun = function(x) { - list( - "N" = rcell(length(x), format = jjcsformat_xx("xx")) + extra_args = list( + ref_path = ref_path, + .stats = aval1_stats, + .formats = .formats_all, + .labels = aval1_labels, + .indent_mods = aval1_indent_mods + ) + ) + +if (show_subj_years) { + lyt <- lyt |> + analyze( + "AVAL_yr", + afun = a_summary, + var_labels = sprintf("Duration of treatment~[super a], (%s)", get_unit(trtdur)), + show_labels = "hidden", + indent_mod = 2L, + extra_args = list( + ref_path = ref_path, + .stats = c("sum"), + .formats = .formats_all, + .labels = c(sum = "Total treatment (subject years)") ) - } - ) %>% - analyze( - "AVAL1", - nested = TRUE, - var_labels = "Total number of administrations", - show_labels = "hidden", - indent_mod = 2L, - afun = function(x) { - list( - "Mean (SD)" = rcell( - c(mean(x), sd(x)), - format = jjcsformat_xx("xx.x (xx.xx)") + ) +} + +if (comp_btw_group) { + diff_lbl <- "Difference in means [Study Treatment] vs. [Placebo] (95% CI)" + diff_fmt <- jjcsformat_xx("xx.xx (xx.xx, xx.xx)") + if (ancova) { + message("difference between groups using ancova approach") + lyt <- lyt |> + analyze( + vars = "AVAL1", + table_names = "AVAL_diff", + afun = a_summarize_ancova_j, + show_labels = "hidden", + indent_mod = 2L, + extra_args = list( + ref_path = ref_path, + variables = list(arm = trtvar, covariates = NULL), + conf_level = 0.95, + weights_combo = "proportional", + .stats = "lsmean_diff_with_ci", + .formats = .formats_all, + .labels = c(lsmean_diff_with_ci = diff_lbl) ), - "Median" = rcell(median(x), format = jjcsformat_xx("xx.x")), - "Min, max" = rcell( - c(min(x), max(x)), - format = jjcsformat_xx("xx., xx.") + section_div = " " + ) + } else { + message("difference between groups using 2 sample t-test approach") + lyt <- lyt |> + analyze( + vars = "AVAL1", + table_names = "AVAL_diff_desc", + afun = a_diff_means, + show_labels = "hidden", + indent_mod = 2L, + extra_args = list( + ref_path = ref_path, + conf_level = 0.95, + .stats = "diff_means_est_ci", + .formats = .formats_all, + .labels = c(diff_means_est_ci = diff_lbl) ), - "Interquartile range" = rcell( - c(quantile(x, c(0.25, 0.75), type = 2)), - format = jjcsformat_xx("xx.x, xx.x") - ) + section_div = " " ) - } - ) %>% + } +} + +lyt <- lyt |> analyze( "AVALCAT1", - nested = FALSE, + var_labels = "Duration of treatment, n (%)", afun = a_freq_j, - var_labels = "Total number of administrations, n (%)", - extra_args = extra_args1, + extra_args = extra_args_rr, + indent_mod = 1L, show_labels = "visible", - indent_mod = 1L - ) %>% + section_div = " " + ) + +# Add in analyze for all CRIT variables contained in ex + +lyt <- lyt |> analyze( - "CRIT1", + "CRIT1FL", + var_labels = "Duration of treatment~[super b], n (%)", afun = a_freq_j, - nested = FALSE, - show_labels = "visible", - var_labels = "Total number of administrations~[super a], n (%)", - extra_args = extra_args1, - indent_mod = 1L + extra_args = append( + extra_args_rr, + list(label_map = ex_lblmap, val = "Y") + ), + indent_mod = 1L, + show_labels = "visible" ) - -# Add in analzye for all remaining CRIT variables contained in ex -for (i in 2:countcritvars) { - lyt <- lyt %>% +if (countcritvars > 1) { + critvars <- paste0("CRIT", 2:countcritvars, "FL") + lyt <- lyt |> analyze( - paste0("CRIT", i, "FL"), + critvars, afun = a_freq_j, - extra_args = list( - val = "Y", - label = critlbls[[i]], - denom = "n_df", - .stats = c("count_unique_fraction") + extra_args = append( + extra_args_rr, + list(label_map = ex_lblmap, val = "Y") ), indent_mod = 2L, show_labels = "hidden" ) } +# Total Number of Administrations +if (show_totadmin) { + lyt <- lyt |> + analyze( + "AVAL2", + nested = FALSE, + var_labels = "Total number of administrations", + show_labels = "visible", + afun = a_summary, + extra_args = list( + .stats = aval1_stats, + .formats = .formats_all0, + .labels = aval1_labels, + .indent_mods = aval1_indent_mods + ) + ) -lyt <- lyt %>% - analyze( - "AVAL2", - table_names = "AVAL2x", - var_labels = "Cumulative dose ([units])", - nested = FALSE, - show_labels = "visible", - indent_mod = 0L, - afun = function(x) { - list( - "N" = rcell(length(x), format = jjcsformat_xx("xx")) + if (show_totadmin_avalcat) { + lyt <- lyt |> + analyze( + "AVALCAT2", + nested = FALSE, + afun = a_freq_j, + var_labels = "Total number of administrations, n (%)", + extra_args = extra_args_rr, + show_labels = "visible", + indent_mod = 1L ) - } - ) %>% - analyze( - "AVAL2", - nested = TRUE, - var_labels = "Cumulative dose ([units])", - show_labels = "hidden", - indent_mod = 2L, - afun = function(x) { - list( - "Mean (SD)" = rcell( - c(mean(x), sd(x)), - format = jjcsformat_xx("xx.x (xx.xx)") + } + + if (show_totadmin_crit) { + lyt <- lyt |> + analyze( + "CRIT1FL_NDOS", + afun = a_freq_j, + nested = FALSE, + show_labels = "visible", + var_labels = "Total number of administrations~[super b], n (%)", + extra_args = list( + val = "Y", + label = critlbls[[1]], + denom = "n_df", + .stats = c("count_unique_fraction") ), - "Median" = rcell(median(x), format = jjcsformat_xx("xx.x")), - "Min, max" = rcell( - c(min(x), max(x)), - format = jjcsformat_xx("xx., xx.") - ), - "Interquartile range" = rcell( - c(quantile(x, c(0.25, 0.75), type = 2)), - format = jjcsformat_xx("xx.x, xx.x") - ) + indent_mod = 1L ) + + # Add in analyze for all remaining CRIT variables contained in ex + for (i in 2:count2critvars) { + lyt <- lyt |> + analyze( + paste0("CRIT", i, "FL_NDOS"), + afun = a_freq_j, + extra_args = list( + val = "Y", + label = critlbls[[i]], + denom = "n_df", + .stats = c("count_unique_fraction") + ), + indent_mod = 2L, + show_labels = "hidden" + ) } - ) %>% + } +} +# end show_totadmin + +# Cumulative Dose [unit] +lyt <- lyt |> + analyze( + "AVAL3", + nested = FALSE, + var_labels = sprintf("Cumulative dose (%s)", get_unit("CUMDOSE")), + show_labels = "visible", + afun = a_summary, + extra_args = list( + .stats = aval1_stats, + .formats = .formats_all0, + .labels = aval1_labels, + .indent_mods = aval1_indent_mods + ) + ) |> append_topleft("Parameter") -result <- build_table(lyt, ex, alt_counts_df = adsl) +result <- build_table(lyt, ex, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Add titles and footnotes: @@ -301,6 +533,7 @@ result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 31, 31, 31, 31) -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") +colwidth <- c(64, 34, 35, 32, 31) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsiex03b.R b/tests/testthat/source_code/tsiex03b.R new file mode 100644 index 00000000..54d499fc --- /dev/null +++ b/tests/testthat/source_code/tsiex03b.R @@ -0,0 +1,372 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) + +################################################################################ +# Define script level parameters: +################################################################################ + +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +# - Define how to create combined treatment columns (if required) +################################################################################ + +tblid <- "TSIEX03b" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + + +trtvar <- "TRT01A" +popfl <- "SAFFL" +combined_colspan_trt <- TRUE +ctrl_grp <- "Placebo" + +# dose_dly will be TRUE if study collected dose delay by default it is FALSE +dose_dly <- TRUE + +# trt_period will be TRUE if APERIOD details available by default it is FALSE +trt_period <- TRUE + +if (combined_colspan_trt == TRUE) { + # Set up levels and label for the required combined columns + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + + # choose if any facets need to be removed - e.g remove the combined column for placebo + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} + +################################################################################ +# Process Data: +################################################################################ + +# Read in required data +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) + +adsl$colspan_trt <- factor( + ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), + levels = c("Active Study Agent", " ") +) + +core_ex_vars <- c( + "USUBJID", + "AACTPR", + "AACTDU", + "AADJ", + "AADJP", + "AVISIT", + "AVISITN" +) + +# Conditionally include dose delay variables if dose_dly is TRUE +dose_dly_vars <- if (isTRUE(dose_dly)) c("ADOSDLY", "ARSDOSD") else NULL + +# Conditionally include treatment period variables if trt_period is TRUE +period_vars <- if (isTRUE(trt_period)) c("APERIOD", "APERIODC") else NULL + +# Read adex, exclude unscheduled visits, select required variables +adex1 <- adex_jnj |> + filter(!grepl("UNSCHEDULED", AVISIT, ignore.case = TRUE)) |> + select(all_of(core_ex_vars), all_of(dose_dly_vars), all_of(period_vars)) + +# Convert AVISIT to sentence case and apply levels sorted by AVISITN +avisit_levs <- adex1 |> + distinct(AVISIT, AVISITN) |> + arrange(AVISITN) |> + pull(AVISIT) |> + stringr::str_to_sentence() +adex1$AVISIT <- stringr::str_to_sentence(adex1$AVISIT) +adex1$AVISIT <- factor(adex1$AVISIT, levels = avisit_levs) + +adex1a <- adex1 |> + mutate( + AACTx = AACTPR, + AADJx = AADJP, + XXX = "Action taken prior to [injection/infusion]" + ) + +adex1b <- adex1 |> + mutate( + AACTx = AACTDU, + AADJx = AADJ, + XXX = "Action taken during [injection/infusion]" + ) + +if (isTRUE(dose_dly)) { + adex1c <- adex1 |> + filter(ADOSDLY == "Y") |> + mutate( + AACTx = ADOSDLY, + AADJx = ARSDOSD, + XXX = "Dose delay" + ) + + adex_all <- bind_rows(adex1a, adex1b, adex1c) +} else { + adex_all <- bind_rows(adex1a, adex1b) +} + +any_label <- if (isTRUE(dose_dly)) { + "Any action taken or dose delay of study treatment~[super a]" +} else { + "Any action taken of study treatment~[super a]" +} +adex_any <- adex_all |> mutate(ANY = any_label) + +adex <- bind_rows(adex_any, adex_all) + +# Adding factor level for categories +adex$ANY <- factor(adex$ANY, levels = unique(adex$ANY)) + +# Convert ARSDOSD to sentence case +if (isTRUE(dose_dly)) { + adex$ARSDOSD <- factor( + stringr::str_to_sentence(as.character(adex$ARSDOSD)), + levels = stringr::str_to_sentence(levels(adex$ARSDOSD)) + ) +} + +# Re-apply APERIOD/APERIODC factor levels after bind_rows (bind drops levels) +if (isTRUE(trt_period)) { + adex$APERIOD <- factor(adex$APERIOD, levels = c("1", "2")) + adex$APERIODC <- factor(adex$APERIODC, levels = c("Period 1", "Period 2")) +} + +xxx_levels <- c( + "Action taken prior to [injection/infusion]", + "Dose delay", + "Action taken during [injection/infusion]" +) + +# control levels of new variables AACTx and AADJx +aact_levels <- c( + "DOSE REDUCED COMPARED TO PRIOR INFUSION", + "INFUSION DELAYED WITHIN THE CYCLE", + "INFUSION RATE DECREASED COMPARED TO PRIOR INFUSION", + "INFUSION SKIPPED (AND NOT MADE UP)", + "STUDY DRUG PERMANENTLY DISCONTINUED", + "INFUSION ABORTED", + "INFUSION INTERRUPTED", + "INFUSION RATE INCREASED" +) + +aact_labels <- c( + "Dose reduced", + "Infusion delayed", + "Infusion rate decreased", + "Infusion skipped", + "Study agent permanently discontinued", + "Infusion aborted", + "Infusion interrupted", + "Infusion rate increased" +) + +adex$AACTx <- factor( + as.character(adex$AACTx), + levels = aact_levels, + labels = aact_labels +) + +adex$AADJx <- factor( + stringr::str_to_sentence(as.character(adex$AADJx)), + levels = stringr::str_to_sentence(levels(c(adex$AADJ, adex$AADJP))) +) + +### Note the following levels are not used on the table, not sure if this is OK --- +### this is out of scope for template script +### how standard is this table and the levels of the variables on the current dataset + standard ADaM??? +setdiff(levels(adex$AACTPR), aact_levels) +setdiff(levels(adex$AACTDU), aact_levels) + +# join data together +ex <- adex |> inner_join(adsl, by = c("USUBJID")) + +################################################################################ +# Define layout and build table: +################################################################################ +# Build colspan mapping for active vs control treatment column headers +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) +# Reference path used for column count denominators (control group anchor) +ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) + +# extra_args1: frequency args for treatment period analysis (denominator by APERIOD) +extra_args1 <- list( + .stats = "count_unique_fraction", + denom = "n_parentdf", + denom_by = "APERIOD", + drop_levels = TRUE +) +# extra_args2: frequency args for time point analysis (denominator by AVISIT) +extra_args2 <- list( + .stats = "count_unique_fraction", + denom = "n_parentdf", + denom_by = "AVISIT", + drop_levels = TRUE +) + +# --- Column structure --- +lyt0 <- rtables::basic_table( + top_level_section_div = " ", + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) + +if (combined_colspan_trt == TRUE) { + lyt <- lyt0 |> split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt0 |> split_cols_by(trtvar) +} + +# --- Section 1: Overall summary (ANY) --- +lyt <- lyt |> + split_rows_by( + "ANY", + split_label = "Time Point", + split_fun = drop_split_levels, + label_pos = "topleft", + indent_mod = 0L, + section_div = " " + ) |> + split_rows_by("AACTx", split_fun = drop_split_levels, section_div = " ") |> + summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) |> + analyze("AADJx", afun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) +if (isTRUE(dose_dly)) { + lyt <- lyt |> + split_rows_by("XXX", split_fun = keep_split_levels(c("Dose delay")), indent_mod = 1L) |> + summarize_row_groups("XXX", cfun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) |> + analyze("ARSDOSD", afun = a_freq_j, extra_args = list(.stats = "count_unique_fraction")) +} + +# --- Section 2: Treatment Period breakdown (only when trt_period = TRUE) --- +if (isTRUE(trt_period)) { + lyt <- lyt |> + split_rows_by( + "APERIOD", + labels_var = "APERIODC", + split_fun = keep_split_levels(c("1", "2")), + child_labels = "visible", + indent_mod = 0L, + section_div = " " + ) + if (isTRUE(dose_dly)) { + lyt <- lyt |> + split_rows_by("XXX", split_fun = keep_split_levels(xxx_levels), section_div = " ") |> + split_rows_by("AACTx", split_fun = drop_split_levels, section_div = " ") |> + summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = extra_args1) |> + analyze("AADJx", afun = a_freq_j, extra_args = extra_args1) + } else { + lyt <- lyt |> + split_rows_by( + "XXX", + split_fun = keep_split_levels(c( + "Action taken prior to [injection/infusion]", + "Action taken during [injection/infusion]" + )), + section_div = " " + ) |> + split_rows_by("AACTx", split_fun = drop_split_levels, section_div = " ") |> + summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = extra_args1) |> + analyze("AADJx", afun = a_freq_j, extra_args = extra_args1) + } +} + +# --- Section 3: Time Point (AVISIT) breakdown --- +lyt <- lyt |> + split_rows_by( + "AVISIT", + split_fun = drop_split_levels, + child_labels = "visible", + indent_mod = 0L, + section_div = " " + ) +if (isTRUE(dose_dly)) { + lyt <- lyt |> + split_rows_by("XXX", split_fun = keep_split_levels(xxx_levels), section_div = " ") |> + summarize_row_groups("XXX", cfun = a_freq_j, extra_args = list(.stats = "n_df")) |> + split_rows_by("AACTx", split_fun = drop_split_levels, section_div = " ") |> + summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = extra_args2) |> + analyze("AADJx", afun = a_freq_j, extra_args = extra_args2) |> + append_topleft(" Action Taken or Dose Delay") |> + append_topleft(" Reason, n (%)") +} else { + lyt <- lyt |> + split_rows_by( + "XXX", + split_fun = keep_split_levels(c( + "Action taken prior to [injection/infusion]", + "Action taken during [injection/infusion]" + )), + section_div = " " + ) |> + summarize_row_groups("XXX", cfun = a_freq_j, extra_args = list(.stats = "n_df")) |> + split_rows_by("AACTx", split_fun = drop_split_levels, section_div = " ") |> + summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = extra_args2) |> + analyze("AADJx", afun = a_freq_j, extra_args = extra_args2) |> + append_topleft(" Action Taken") |> + append_topleft(" Reason, n (%)") +} + +result <- build_table(lyt, ex, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Prune table to remove all the rows with 0 counts or no data to report across all sections +################################################################################ + +result <- prune_table(result, prune_func = prune_zeros_only) + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, label_width_ins = 2.4, orientation = "portrait") diff --git a/tests/testthat/source_code/tsiex04.R b/tests/testthat/source_code/tsiex04.R deleted file mode 100644 index 0149aa0f..00000000 --- a/tests/testthat/source_code/tsiex04.R +++ /dev/null @@ -1,230 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsiex04.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsiex04: Number of Cycles Received -## Author: Johnson & Johnson Innovative Medicine -## Date: 29 Jan 2024 -## Input: ADSL, ADEXSUM -## Output: TSIEX04.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Define levels which will control ordering for AVALCAT1 in the table -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSIEX04" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - - -trtvar <- "TRT01A" -popfl <- "SAFFL" - -catlevels <- c("1 to <10", "10 to <20", ">=20") - -combined_colspan_trt <- TRUE - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -# Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -# If AVISIT is not present in ADEXSUM than create 'Overall' as the Visit, which is used -# for the filtering AVISIT records if it does exist -adexsum <- adexsum_jnj %>% - mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") %>% - filter(PARAMCD == "NUMCYC" & !is.na(AVAL) & VISIT == "Overall") %>% - select(USUBJID, PARAMCD, AVAL, AVALCAT1, starts_with("CRIT")) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -# join data together -ex <- adexsum %>% inner_join(., adsl, by = c("USUBJID")) - -# Keep only columns with some data in which will remove any unwanted CRITy variables -ex <- ex[, colSums(is.na(ex)) < nrow(ex)] - -# Work out how many CRITy vars we have left -excritvars <- ex %>% - select(num_range("CRIT", 1:99)) - -countcritvars <- length(names(excritvars)) - -# Drop unwanted levels for all CRITy variables you have remaining in ex and also for AVALCAT1 -critlbls <- list() -for (i in 1:countcritvars) { - variable_name <- paste0("CRIT", i) - ex[[variable_name]] <- droplevels(ex[[variable_name]]) - critlbls[[i]] <- unique(as.character(ex[[variable_name]])) -} - -ex$AVALCAT1 <- droplevels(ex$AVALCAT1) -ex$AVALCAT1 <- factor(ex$AVALCAT1, levels = catlevels) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) -ref_path <- c("colspan_trt", " ", trtvar, "Placebo") -################################################################################ -# Define layout and build table: -################################################################################ - -lyt <- rtables::basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - -lyt <- lyt %>% - analyze( - "STUDYID", - var_labels = "Total number of cycles received", - afun = a_freq_j, - extra_args = list(label = "N", .stats = "n_df"), - indent_mod = 0L, - show_labels = "visible" - ) %>% - analyze("AVAL", show_labels = "hidden", indent_mod = 2L, afun = function(x) { - list( - "Mean (SD)" = rcell( - c(mean(x), sd(x)), - format = jjcsformat_xx("xx.x (xx.xx)") - ), - "Median" = rcell(median(x), format = jjcsformat_xx("xx.x")), - "Min, max" = rcell(c(min(x), max(x)), format = jjcsformat_xx("xx., xx.")) - ) - }) %>% - analyze( - "AVALCAT1", - nested = FALSE, - var_labels = "Total number of cycles received, n (%)", - afun = a_freq_j, - extra_args = list(denom = "n_df", .stats = c("count_unique_fraction")), - indent_mod = 1L, - show_labels = "visible" - ) %>% - analyze( - "CRIT1FL", - var_labels = "Total number of cycles received~[super a], n (%)", - afun = a_freq_j, - extra_args = list( - val = "Y", - label = critlbls[[1]], - denom = "n_df", - .stats = c("count_unique_fraction") - ), - indent_mod = 1L, - show_labels = "visible", - nested = FALSE - ) - -# Add in analzye for all remaining CRIT variables contained in ex -for (i in 2:countcritvars) { - lyt <- lyt %>% - analyze( - paste0("CRIT", i, "FL"), - afun = a_freq_j, - extra_args = list( - val = "Y", - label = critlbls[[i]], - denom = "n_df", - .stats = c("count_unique_fraction") - ), - indent_mod = 2L, - show_labels = "hidden" - ) -} - -lyt <- lyt %>% - append_topleft("Parameter") - -result <- build_table(lyt, ex, alt_counts_df = adsl) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ -colwidth <- c(64, 21, 21, 23, 21) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tsiex05.R b/tests/testthat/source_code/tsiex05.R new file mode 100644 index 00000000..b955acbb --- /dev/null +++ b/tests/testthat/source_code/tsiex05.R @@ -0,0 +1,355 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) +library(haven) + +################################################################################ +# Define script level parameters: +################################################################################ + +tblid <- "TSIEX05" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +trtvar <- "TRT01A" +popfl <- "SAFFL" + +# Specifies the study agent to filter exposure data; leave empty (NULL or "") to include all treatment groups +study_agent <- "XANOMELINE" + +# add required levels for dose +dose_level <- c(7.5, 15) + +# Set to FALSE to hide dose level breakdown rows in the layout +show_dose_level <- TRUE + +# Set Parameters for Dose interruptions /Dose skipped (and not made up) /Dose delay +# Dose interuption then use ANL03FL == "Y" and INTCAT variable +# Dose skipped (and not made up) then use flag ANL04FL == "Y" and SKPCAT +# Dose delay then use ADOSDLY == "Y" and DLYCAT +analysis_flag <- "ANL03FL" +analysis_variable <- "INTCAT" +analysis_label <- "dose interruptions" + +# Threshold for dose delay; adjust according to study +dly_threshold <- 3 + +trt_levels <- if (!is.null(study_agent) && nzchar(study_agent)) { + c("Xanomeline Low Dose", "Xanomeline High Dose") +} else { + c("Xanomeline Low Dose", "Xanomeline High Dose", "Placebo") +} + +non_active_grp <- if (!is.null(study_agent) && nzchar(study_agent)) NULL else "Placebo" + +combined_colspan_trt <- TRUE + +if (combined_colspan_trt == TRUE) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = c("Xanomeline High Dose", "Xanomeline Low Dose") + ) + if (is.null(non_active_grp)) { + mysplit <- make_split_fun(post = list(add_combo)) + } else { + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) + } +} +################################################################################ +# Process Data: +################################################################################ + +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + select(STUDYID, USUBJID, all_of(c(trtvar, popfl))) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = trt_levels + ) + ) + +if (TRUE) { + adsl <- adsl |> + create_colspan_var( + non_active_grp = if (is.null(non_active_grp)) character(0) else non_active_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) +} + +adex <- adex_jnj |> + select( + STUDYID, + USUBJID, + all_of(c(trtvar, popfl)), + starts_with("ANL"), + ASCHDOSE, + ASCHDOSU, + ADOSDLY, + INTCAT, + SKPCAT, + DLYCAT, + ATRT + ) |> + filter(.data[[popfl]] == "Y", if (!is.null(study_agent) && nzchar(study_agent)) ATRT == study_agent else TRUE) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = trt_levels + ) + ) + +adsl_join <- adsl |> select(STUDYID, USUBJID, colspan_trt) + +ex <- adex |> + inner_join(adsl_join, by = c("STUDYID", "USUBJID")) |> + mutate( + aschdose_chr = as.character(ASCHDOSE), + aschdosu_val = dplyr::first(na.omit(ASCHDOSU)), + ASCHDOSE = factor( + if_else(ANL01FL == "Y", aschdose_chr, NA_character_), + levels = dose_level, + labels = paste("To", dose_level, unique(aschdosu_val)) + ), + ASCHDOSE2 = factor( + if_else(ANL02FL == "Y", aschdose_chr, NA_character_), + levels = dose_level, + labels = paste("To", dose_level, unique(aschdosu_val)) + ), + # Use flag ANL04FL == "Y" for Dose Skipped OR ADOSDLY == "Y" for Dose Delay + ANL_SEC3_FL = if_else(.data[[analysis_flag]] == "Y", "Y", "N"), + !!rlang::sym(paste0(analysis_variable, "1")) := factor( + if_else( + ANL_SEC3_FL == "Y" & (!is.na(.data[[analysis_variable]]) & as.numeric(.data[[analysis_variable]]) == 1), + "Y", + "N" + ), + levels = c("Y", "N") + ), + !!rlang::sym(paste0(analysis_variable, "2")) := factor( + if_else( + ANL_SEC3_FL == "Y" & (!is.na(.data[[analysis_variable]]) & as.numeric(.data[[analysis_variable]]) == 2), + "Y", + "N" + ), + levels = c("Y", "N") + ), + !!rlang::sym(paste0(analysis_variable, "3")) := factor( + if_else( + ANL_SEC3_FL == "Y" & + (!is.na(.data[[analysis_variable]]) & as.numeric(.data[[analysis_variable]]) >= dly_threshold), + "Y", + "N" + ), + levels = c("Y", "N") + ) + ) |> + select(-aschdose_chr, -aschdosu_val) + +if (TRUE) { + colspan_trt_map <- if (!is.null(non_active_grp)) { + create_colspan_map( + adsl, + non_active_grp = non_active_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) + } else { + data.frame( + colspan_trt = rep("Active Study Agent", nlevels(adsl[[trtvar]])), + TRT01A = levels(adsl[[trtvar]]) + ) |> + setNames(c("colspan_trt", trtvar)) + } +} + +################################################################################ +# Define layout and build table: +################################################################################ + +lyt <- basic_table( + show_colcounts = TRUE, + colcount_format = "N=xx", + top_level_section_div = " " +) |> + append_topleft("Dose Modification, n (%)") + +if (TRUE) { + lyt <- lyt |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) +} + +if (combined_colspan_trt == TRUE) { + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) +} else { + lyt <- lyt |> split_cols_by(trtvar) +} + +lyt <- lyt |> + # ── Section 1: Prescribed dose reductions ────────────────────────────────── + analyze( + "ANL01FL", + var_labels = "Prescribed dose reductions", + afun = a_freq_j, + extra_args = list( + val = "Y", + label = ">=1 dose reduction", + denom = "n_df", + .stats = "count_unique_fraction" + ), + show_labels = "visible", + indent_mod = 0L + ) + +if (show_dose_level) { + lyt <- lyt |> + analyze( + "ASCHDOSE", + afun = a_freq_j, + extra_args = list( + denom = "N_col", + .stats = "count_unique_fraction" + ), + show_labels = "hidden", + indent_mod = 2L, + nested = TRUE + ) +} + +lyt <- lyt |> + # ── Section 2: Prescribed dose reductions due to AEs ─────────────────────── + analyze( + "ANL02FL", + var_labels = "Prescribed dose reductions due to AEs", + afun = a_freq_j, + extra_args = list( + val = "Y", + label = ">=1 dose reduction", + denom = "n_df", + .stats = "count_unique_fraction" + ), + show_labels = "visible", + indent_mod = 0L, + nested = FALSE + ) + +if (show_dose_level) { + lyt <- lyt |> + analyze( + "ASCHDOSE2", + afun = a_freq_j, + extra_args = list( + denom = "N_col", + .stats = "count_unique_fraction" + ), + show_labels = "hidden", + indent_mod = 2L, + nested = TRUE, + table_names = "aschdose2" + ) +} + +lyt <- lyt |> + # ── Section 3: Dose interruptions / dose skipped / dose delay ────────────── + analyze( + "ANL_SEC3_FL", + var_labels = stringr::str_to_sentence(analysis_label), # /Dose skipped (and not made up)/Dose delay + afun = a_freq_j, + extra_args = list( + val = "Y", + label = paste(">=1", analysis_label), # /dose skipped (and not made up)/dose delay + denom = "n_df", + .stats = "count_unique_fraction" + ), + show_labels = "visible", + indent_mod = 0L, + nested = FALSE + ) |> + analyze( + paste0(analysis_variable, "1"), + afun = a_freq_j, + extra_args = list( + val = "Y", + label = "1", + denom = "N_col", + .stats = "count_unique_fraction" + ), + show_labels = "hidden", + indent_mod = 2L, + nested = TRUE + ) |> + analyze( + paste0(analysis_variable, "2"), + afun = a_freq_j, + extra_args = list( + val = "Y", + label = "2", + denom = "N_col", + .stats = "count_unique_fraction" + ), + show_labels = "hidden", + indent_mod = 2L, + nested = TRUE + ) |> + analyze( + paste0(analysis_variable, "3"), + afun = a_freq_j, + extra_args = list( + val = "Y", + label = paste0(">=", dly_threshold), + denom = "N_col", + .stats = "count_unique_fraction" + ), + show_labels = "hidden", + indent_mod = 2L, + nested = TRUE + ) + +result <- build_table(lyt, ex, alt_counts_df = adsl, round_type = "sas") + +################################################################################ +# Add pruning steps +# Add titles and footnotes: +################################################################################ +result <- prune_table( + result, + prune_func = function(tt) { + if (obj_name(tt) %in% c("ASCHDOSE", "ASCHDOSE2", paste0(analysis_variable, 1:3))) { + prune_empty_level(tt) + } else { + FALSE + } + } +) + +result <- set_titles(result, tab_titles) + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(62, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tsiex06.R b/tests/testthat/source_code/tsiex06.R index b44ec673..54f8e406 100644 --- a/tests/testthat/source_code/tsiex06.R +++ b/tests/testthat/source_code/tsiex06.R @@ -1,28 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsiex06.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsiex06: Subjects Who Received Study -## Treatment by Time Point -## Author: Johnson & Johnson Innovative Medicine -## Date: 29 Jan 2024 -## Input: ADSL, ADEX -## Output: TSIEX06.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -78,18 +53,30 @@ if (combined_colspan_trt == TRUE) { ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(USUBJID, all_of(trtvar), all_of(popfl)) - -adex <- adex_jnj %>% - filter(AOCCUR == "Y" & !grepl("UNSCHEDULED", AVISIT, ignore.case = TRUE)) %>% - select(USUBJID, AOCCUR, AVISIT, AVISITN) +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) + +adex <- adex_jnj |> + filter(AOCCUR == "Y" & !is.na(AVISIT) & !grepl("UNSCHEDULED|SCREENING", AVISIT, ignore.case = TRUE)) |> + select(STUDYID, USUBJID, AOCCUR, AVISIT, AVISITN) |> + mutate( + AVISIT := factor( + stringr::str_to_sentence(as.character(AVISIT)), + levels = stringr::str_to_sentence(unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))]) + ) + ) -# Convert AVISIT to sentence case and apply levels to maintain ordering -avisit_levs <- stringr::str_to_sentence(levels(adex$AVISIT)) -adex$AVISIT <- stringr::str_to_sentence(adex$AVISIT) -adex$AVISIT <- factor(adex$AVISIT, levels = avisit_levs) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -97,7 +84,15 @@ adsl$colspan_trt <- factor( ) # join data together -ex <- adex %>% inner_join(., adsl, by = c("USUBJID")) +ex <- adex |> inner_join(adsl, by = c("STUDYID", "USUBJID")) + +ex <- ex |> + mutate( + SUBJ_FLAG = factor( + "Subjects receiving study treatment, n (%)", + levels = "Subjects receiving study treatment, n (%)" + ) + ) colspan_trt_map <- create_colspan_map( adsl, @@ -116,30 +111,35 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% - tern::count_occurrences( +lyt <- lyt |> + split_rows_by( + "SUBJ_FLAG", + split_fun = drop_split_levels, + indent_mod = 0L + ) |> + analyze( "AVISIT", - .stats = "count_fraction_fixed_dp", - .formats = c("count_fraction_fixed_dp" = jjcsformat_count_fraction), - var_labels = "Subjects receiving study treatment, n (%)", - show_labels = "visible" + afun = a_freq_j, + extra_args = list(.stats = "count_unique_fraction"), + indent_mod = 0L ) -result <- build_table(lyt, ex, alt_counts_df = adsl) + +result <- build_table(lyt, ex, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Add titles and footnotes: @@ -150,6 +150,7 @@ result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 21, 21, 21, 21) + +colwidth <- c(64, 21, 23, 21, 21) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tsiex07.R b/tests/testthat/source_code/tsiex07.R index 4defb3c5..25b288b9 100644 --- a/tests/testthat/source_code/tsiex07.R +++ b/tests/testthat/source_code/tsiex07.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsiex07.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsiex07: Dose Levels Over Time -## Author: Johnson & Johnson Innovative Medicine -## Date: 15 Jan 2024 -## Input: ADSL, ADEX -## Output: TSIEX07.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -51,53 +27,62 @@ tab_titles <- list( trtvar <- "TRT01A" popfl <- "SAFFL" -dose_order <- c("60", "120", "180", "240", "300", "480", "720", "960", "Total") - +dose_order <- c("7.5", "15", "Total") ################################################################################ # Process Data: ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y" & !!rlang::sym(trtvar) != "Placebo") %>% - select(USUBJID, all_of(trtvar), all_of(popfl)) - -adex <- adex_jnj %>% - filter(!grepl("UNSCHEDULED", AVISIT, ignore.case = TRUE)) %>% - filter(!is.na(ADOSE)) %>% - mutate(ADOSEC = as.factor(ADOSE)) %>% - select(USUBJID, ADOSEC, AVISIT, AVISITN) - -# Convert AVISIT to sentence case and apply levels to maintain ordering -avisit_levs <- stringr::str_to_sentence(levels(adex$AVISIT)) -adex$AVISIT <- stringr::str_to_sentence(adex$AVISIT) -adex$AVISIT <- factor(adex$AVISIT, levels = avisit_levs) +adsl <- adsl_jnj |> + filter(!!rlang::sym(popfl) == "Y" & !!rlang::sym(trtvar) != "Placebo") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose" + ) + ) + ) + +adex <- adex_jnj |> + filter(!is.na(ADOSE) & !is.na(AVISIT) & !grepl("SCREENING", AVISIT, ignore.case = TRUE)) |> + mutate(ADOSEC = as.factor(ADOSE)) |> + select(STUDYID, USUBJID, ADOSEC, AVISIT, AVISITN) |> + mutate( + AVISIT := factor( + stringr::str_to_sentence(as.character(AVISIT)), + levels = stringr::str_to_sentence(unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))]) + ) + ) # Create Total column manually as we cannot use the table layout option since patients can # appear in multiple dose level columns -extot_ <- adex %>% - group_by(USUBJID, AVISIT) %>% - slice(1) %>% - mutate(ADOSEC = "Total") %>% +extot_ <- adex |> + group_by(USUBJID, AVISIT) |> + slice(1) |> + mutate(ADOSEC = "Total") |> ungroup() extot <- bind_rows(adex, extot_) # join data together -ex <- extot %>% inner_join(., adsl, by = c("USUBJID")) +ex <- extot |> inner_join(adsl, by = c("STUDYID", "USUBJID")) ex$colspan_trt <- factor( ifelse(ex$ADOSEC == "Total", " ", "Active Study Agent"), levels = c("Active Study Agent", " ") ) + ex$ADOSEC <- factor(ex$ADOSEC, levels = dose_order) # Create dataset to be used for column counts -adex_unique <- ex %>% - group_by(USUBJID, ADOSEC) %>% - slice(1) %>% +adex_unique <- ex |> + group_by(USUBJID, ADOSEC) |> + slice(1) |> ungroup() ################################################################################ @@ -108,19 +93,25 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% - split_cols_by("colspan_trt", split_fun = trim_levels_in_group("ADOSEC")) %>% - split_cols_by("ADOSEC") %>% - tern::count_occurrences( +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_in_group("ADOSEC") + ) |> + split_cols_by("ADOSEC") |> + analyze( "AVISIT", - .stats = "count_fraction_fixed_dp", - .formats = c("count_fraction_fixed_dp" = jjcsformat_count_fraction), - var_labels = " ", - show_labels = "hidden" - ) %>% + afun = a_freq_j, + show_labels = "hidden", + extra_args = list( + .stats = "count_unique_fraction", + denom = "N_col" + ) + ) |> append_topleft("Time Point, n (%)") -result <- build_table(lyt, ex, alt_counts_df = adex_unique) +result <- build_table(lyt, ex, alt_counts_df = adex_unique, round_type = "sas") + ################################################################################ # Add titles and footnotes: @@ -131,6 +122,7 @@ result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(15, 19, 19, 21, 19, 21, 21, 21, 25) + +colwidth <- c(15, 21, 23, 23) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "landscape") diff --git a/tests/testthat/source_code/tsiex08.R b/tests/testthat/source_code/tsiex08.R deleted file mode 100644 index e935ce5d..00000000 --- a/tests/testthat/source_code/tsiex08.R +++ /dev/null @@ -1,238 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsiex08.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsiex08: Incidence and Reason for Dose -## Modification -## Author: Johnson & Johnson Innovative Medicine -## Date: 16 Jan 2024 -## Input: ADSL, ADEX -## Output: TSIEX08.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSIEX08" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - -trtvar <- "TRT01A" -popfl <- "SAFFL" -combined_colspan_trt <- TRUE - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -# Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adex1 <- adex_jnj %>% - filter(!grepl("UNSCHEDULED", AVISIT, ignore.case = TRUE)) - -# Convert AVISIT to sentence case and apply levels to maintain ordering -avisit_levs <- stringr::str_to_sentence(levels(adex1$AVISIT)) -adex1$AVISIT <- stringr::str_to_sentence(adex1$AVISIT) -adex1$AVISIT <- factor(adex1$AVISIT, levels = avisit_levs) - -adex2 <- adex_jnj %>% - mutate(AVISIT = "Overall") - -adex_ <- bind_rows(adex1, adex2) - -adex1$AVISIT <- droplevels(adex1$AVISIT) -adex_$AVISIT <- factor( - adex_$AVISIT, - levels = c("Overall", levels(adex1$AVISIT)) -) - -adex <- adex_ %>% - select(USUBJID, ACAT1, ACAT2, AREASOC, AADJ, AVISIT, AVISITN) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - -# join data together -ex <- adex %>% inner_join(., adsl, by = c("USUBJID")) - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = "Placebo", - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) - -################################################################################ -# Define layout and build table: -################################################################################ -# Note : -# variables AREASOC and AADJ contain missing values, these are removed inside a_freq_j when using denom = "n_df" -# either use n_parentdf and denom_by = AVISIT to get proper denominator -# alternative would be to use ex <- df_explicit_na(ex, omit_columns = "colspan_trt", na_level = "") and -# and have denom = "n_df" in extra_args1 and -# add excl_levels = "" to the extra_args in the calls to these 2 variables -# excl_levels cannot be used in the overall extra_args1 as val and excl_levels cannot be used together - -extra_args1 <- list( - .stats = "count_unique_fraction", - denom = "n_parentdf", - denom_by = "AVISIT" -) - -lyt <- rtables::basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - - -lyt <- lyt %>% - split_rows_by( - "AVISIT", - split_label = "Time Point", - split_fun = trim_levels_in_group("STUDYID"), - label_pos = "topleft", - indent_mod = 0L, - section_div = c(" ") - ) %>% - summarize_row_groups( - "AVISIT", - cfun = a_freq_j, - extra_args = list(.stats = "n_df"), - indent_mod = 0L - ) %>% - analyze( - "ACAT2", - afun = a_freq_j, - extra_args = append( - extra_args1, - list(label = "Dose not administered", val = "Dose not administered") - ), - indent_mod = 0L, - show_labels = "hidden" - ) %>% - analyze( - "AREASOC", - afun = a_freq_j, - extra_args = extra_args1, - show_labels = "hidden", - indent_mod = 1L - ) %>% - analyze( - "ACAT1", - afun = a_freq_j, - extra_args = append( - extra_args1, - list(label = "Dose adjusted", val = "Dose adjusted") - ), - indent_mod = 0L, - show_labels = "hidden" - ) %>% - analyze( - "AADJ", - afun = a_freq_j, - extra_args = extra_args1, - show_labels = "hidden", - indent_mod = 1L - ) %>% - append_topleft(" Dose Modification, n (%)") - -result <- build_table(lyt, ex, alt_counts_df = adsl) - -################################################################################ -# Prune table to only keep those that have >0 counts in any treatment column specified -################################################################################ -more_than_zero <- has_count_in_any_col( - atleast = 1, - col_names = c( - "Active Study Agent.Xanomeline High Dose", - "Active Study Agent.Xanomeline Low Dose", - "Active Study Agent.Combined", - " .Placebo" - ) -) - -result <- safe_prune_table(result, keep_rows(more_than_zero)) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ -colwidth <- c(38, 21, 21, 21, 21) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tsiex09.R b/tests/testthat/source_code/tsiex09.R index dc754c2c..de0ce833 100644 --- a/tests/testthat/source_code/tsiex09.R +++ b/tests/testthat/source_code/tsiex09.R @@ -1,28 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsiex09.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsiex09: Distribution of Subjects by -## Study Treatment Lot -## Author: Johnson & Johnson Innovative Medicine -## Date: 29 Jan 2024 -## Input: ADSL, ADEX -## Output: TSIEX09.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -78,12 +53,22 @@ if (combined_colspan_trt == TRUE) { ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + filter(!!rlang::sym(popfl) == "Y") |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) -adex <- adex_jnj %>% - select(USUBJID, ATRT, EXLOT) +adex <- adex_jnj |> + select(STUDYID, USUBJID, ATRT, EXLOT) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -91,9 +76,9 @@ adsl$colspan_trt <- factor( ) # join data together -ex <- adex %>% - inner_join(., adsl, by = c("USUBJID")) %>% - mutate(ATRT = stringr::str_to_sentence(ATRT)) %>% +ex <- adex |> + inner_join(adsl, by = c("STUDYID", "USUBJID")) |> + mutate(ATRT = stringr::str_to_sentence(ATRT)) |> mutate(trttxt = paste0(ATRT, " lots")) ex$trttxt2 <- factor(ex$trttxt) @@ -125,24 +110,24 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> # trick to get 0 for Placebo column for non Placebo lots # we do not want to show this split_rows group label - therefor set child_labels to hidden - split_rows_by("STUDYID", child_labels = "hidden") %>% + split_rows_by("STUDYID", child_labels = "hidden") |> split_rows_by( "trttxt2", split_label = "Study Treatment", @@ -150,17 +135,18 @@ lyt <- lyt %>% label_pos = "topleft", indent_mod = 0L, section_div = c(" ") - ) %>% + ) |> analyze( "EXLOT", afun = a_freq_j, extra_args = extra_args1, indent_mod = 0L, show_labels = "hidden" - ) %>% + ) |> append_topleft(" Lot, n (%)") -result <- build_table(lyt, ex, alt_counts_df = adsl) +result <- build_table(lyt, ex, alt_counts_df = adsl, round_type = "sas") + ################################################################################ # Add titles and footnotes: @@ -171,6 +157,7 @@ result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ + colwidth <- c(40, 21, 21, 21, 21) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tsiex10.R b/tests/testthat/source_code/tsiex10.R index c6b42d87..73142d3a 100644 --- a/tests/testthat/source_code/tsiex10.R +++ b/tests/testthat/source_code/tsiex10.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsiex10.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsiex10: Study Treatment Compliance -## Author: Johnson & Johnson Innovative Medicine -## Date: 29 Jan 2024 -## Input: ADSL, ADEXSUM -## Output: TSIEX10.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -81,16 +57,26 @@ if (combined_colspan_trt == TRUE) { ################################################################################ # Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + filter(!!rlang::sym(popfl) == "Y") |> select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) # If AVISIT is not present in ADEXSUM than create 'Overall' as the Visit, which is used # for the filtering AVISIT records if it does exist -adexsum <- adexsum_jnj %>% - mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") %>% - filter(PARAMCD == "TRTCOMP" & !is.na(AVAL) & VISIT == "Overall") %>% - select(USUBJID, PARAMCD, AVAL, AVALCAT1) +adexsum <- adexsum_jnj |> + mutate(VISIT = if (exists("AVISIT")) AVISIT else "Overall") |> + filter(PARAMCD == "TRTCOMP" & !is.na(AVAL) & VISIT == "Overall") |> + select(STUDYID, USUBJID, PARAMCD, AVAL, AVALCAT1) adsl$colspan_trt <- factor( ifelse(adsl[[trtvar]] == "Placebo", " ", "Active Study Agent"), @@ -98,11 +84,39 @@ adsl$colspan_trt <- factor( ) # join data together -ex <- adexsum %>% inner_join(., adsl, by = c("USUBJID")) +ex <- adexsum |> inner_join(adsl, by = c("STUDYID", "USUBJID")) ex$AVALCAT1 <- droplevels(ex$AVALCAT1) ex$AVALCAT1 <- factor(ex$AVALCAT1, levels = catlevels) +ex$COMP_CAT_LBL <- factor( + "Compliance category~[super a], n (%)", + levels = "Compliance category~[super a], n (%)" +) + +################################################################################ +# Formats for decimal precision control +################################################################################ + +# manual setup example for user +# prec <- dplyr::tibble(PARAMCD, d = 1) +# prec$d[prec$PARAMCD == "TRTCOMP"] <- 0 + +# alternative: use tidytlg make_precision function +# cutoff for decimal is defined in function and if DTYPE="AVERAGE" those records excluded from precison + +.stats_all <- c("mean_sd", "median", "range") +dp <- 1 + +.formats_all <- junco:::fmt_spec_single_d( + d = dp, + stats_in = .stats_all, + fmt_d_def = junco_def_d_all, + fmt_d_in = NULL +) + +fmt_details <- get_fmt_details(.formats_all, as_tibble = TRUE) + colspan_trt_map <- create_colspan_map( adsl, non_active_grp = "Placebo", @@ -120,21 +134,21 @@ lyt <- rtables::basic_table( top_level_section_div = " ", show_colcounts = TRUE, colcount_format = "N=xx" -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) ) if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar, split_fun = mysplit) } else { - lyt <- lyt %>% + lyt <- lyt |> split_cols_by(trtvar) } -lyt <- lyt %>% +lyt <- lyt |> analyze( "STUDYID", var_labels = "Compliance (%)~[super a]", @@ -142,32 +156,39 @@ lyt <- lyt %>% extra_args = list(label = "N", .stats = "n_df"), indent_mod = 0L, show_labels = "visible" - ) %>% - analyze("AVAL", show_labels = "hidden", indent_mod = 2L, afun = function(x) { - list( - "Mean (SD)" = rcell( - c(mean(x), sd(x)), - format = jjcsformat_xx("xx.x (xx.xx)") - ), - "Median" = rcell(median(x), format = jjcsformat_xx("xx.x")), - "Min, max" = rcell(c(min(x), max(x)), format = jjcsformat_xx("xx., xx.")) + ) |> + analyze( + "AVAL", + show_labels = "hidden", + indent_mod = 2L, + afun = a_summary, + extra_args = list( + .stats = .stats_all, + .formats = .formats_all, + .labels = c(range = "Min, max") ) - }) %>% + ) |> + split_rows_by( + "COMP_CAT_LBL", + nested = FALSE, + split_fun = drop_split_levels, + label_pos = "hidden", + indent_mod = -1L + ) |> analyze( "AVALCAT1", - nested = FALSE, - var_labels = "Compliance category~[super a], n (%)", afun = a_freq_j, extra_args = list( denom = "n_df", .stats = c("count_unique_fraction") ), indent_mod = 1L, - show_labels = "visible" - ) %>% + show_labels = "hidden" + ) |> append_topleft("Parameter") -result <- build_table(lyt, ex, alt_counts_df = adsl) +result <- build_table(lyt, ex, alt_counts_df = adsl, round_type = "sas") + ################################################################################ # Add titles and footnotes: @@ -178,6 +199,7 @@ result <- set_titles(result, tab_titles) ################################################################################ # Convert to tbl file and output table ################################################################################ -colwidth <- c(64, 23, 23, 23, 23) + +colwidth <- c(62, 27, 27, 27, 27) tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tsiex11.R b/tests/testthat/source_code/tsiex11.R deleted file mode 100644 index 9cd5dda5..00000000 --- a/tests/testthat/source_code/tsiex11.R +++ /dev/null @@ -1,317 +0,0 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsiex11.R -## R version: 4.2.1 -## junco version: 1.0 -## Short Description: Program to create tsiex11: Incidence and Reasons for -## Treatment Modifications for Infusions -## Author: Johnson & Johnson Innovative Medicine -## Date: 06 Feb 2024 -## Input: ADSL, ADEXSUM -## Output: TSIEX11.rtf -## Remarks: Template R script version using rtables framework -## -## Modification History: -## Rev #: 1 -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep Environment -################################################################################ - -library(envsetup) -library(tern) -library(dplyr) -library(rtables) -library(junco) - -################################################################################ -# Define script level parameters: -################################################################################ - -################################################################################ -# - Define output ID and file location -# - Define treatment variable used (default=TRT01A) -# - Define population flag used (default=SAFFL) -# - Choose whether or not you want to present a combined active treatment column (default=TRUE) -# - Define how to create combined treatment columns (if required) -################################################################################ - -tblid <- "TSIEX11" -fileid <- write_path(opath, tblid) -tab_titles <- list( - title = "Dummy Title", - subtitles = NULL, - main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" -) - - -trtvar <- "TRT01A" -popfl <- "SAFFL" -combined_colspan_trt <- TRUE -ctrl_grp <- "Placebo" - -if (combined_colspan_trt == TRUE) { - # Set up levels and label for the required combined columns - add_combo <- add_combo_facet( - "Combined", - label = "Combined", - levels = c("Xanomeline High Dose", "Xanomeline Low Dose") - ) - - # choose if any facets need to be removed - e.g remove the combined column for placebo - rm_combo_from_placebo <- cond_rm_facets( - facets = "Combined", - ancestor_pos = NA, - value = " ", - split = "colspan_trt" - ) - - mysplit <- make_split_fun(post = list(add_combo, rm_combo_from_placebo)) -} - -################################################################################ -# Process Data: -################################################################################ - -# Read in required data -adsl <- adsl_jnj %>% - filter(!!rlang::sym(popfl) == "Y") %>% - select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - - -core_ex_vars <- c( - "USUBJID", - "AACTPR", - "AACTDU", - "AADJ", - "AADJP", - "AVISIT", - "AVISITN" -) - -adex1 <- adex_jnj %>% - filter(!grepl("UNSCHEDULED", AVISIT, ignore.case = TRUE)) %>% - select(all_of(core_ex_vars)) - -# Convert AVISIT to sentence case and apply levels to maintain ordering -avisit_levs <- stringr::str_to_sentence(levels(adex1$AVISIT)) -adex1$AVISIT <- stringr::str_to_sentence(adex1$AVISIT) -adex1$AVISIT <- factor(adex1$AVISIT, levels = avisit_levs) - - -adex1a <- adex1 %>% - mutate( - AACTx = AACTPR, - AADJx = AADJ, - XXX = "Prior to infusion" - ) - -adex1b <- adex1 %>% - mutate( - AACTx = AACTDU, - AADJx = AADJP, - XXX = "During infusion" - ) - -adex1c <- bind_rows(adex1a, adex1b) -adex1c$XXX <- factor( - adex1c$XXX, - levels = c("Prior to infusion", "During infusion") -) - -### Overall visit - -adex2 <- adex_jnj %>% - mutate(AVISIT = "Overall") %>% - select(all_of(core_ex_vars)) - -adex2a <- adex2 %>% - mutate( - AACTx = AACTPR, - AADJx = AADJ, - XXX = "Prior to infusion" - ) - -adex2b <- adex2 %>% - mutate( - AACTx = AACTDU, - AADJx = AADJP, - XXX = "During infusion" - ) - -adex2c <- bind_rows(adex2a, adex2b) -adex2c$XXX <- factor( - adex2c$XXX, - levels = c("Prior to infusion", "During infusion") -) - -adex <- bind_rows(adex1c, adex2c) - -# control levels of AVISIT -adex$AVISIT <- factor(adex$AVISIT, levels = c("Overall", levels(adex1$AVISIT))) - -# control levels of new variables AACTx and AADJx -aact_levels <- c( - "DOSE REDUCED COMPARED TO PRIOR INFUSION", - "INFUSION DELAYED WITHIN THE CYCLE", - "INFUSION RATE DECREASED COMPARED TO PRIOR INFUSION", - "INFUSION SKIPPED (AND NOT MADE UP)", - "STUDY DRUG PERMANENTLY DISCONTINUED", - "INFUSION ABORTED", - "INFUSION INTERRUPTED", - "INFUSION RATE INCREASED" -) - -aact_labels <- c( - "Dose reduced", - "Infusion delayed", - "Infusion rate decreased", - "Infusion skipped", - "Study agent permanently discontinued", - "Infusion aborted", - "Infusion interrupted", - "Infusion rate increased" -) - -adex$AACTx <- factor( - as.character(adex$AACTx), - levels = aact_levels, - labels = aact_labels -) - -adex$AADJx <- factor(adex$AADJx, levels = levels(c(adex$AADJ, adex$AADJP))) - -### Note the following levels are not used on the table, not sure if this is OK --- -### this is out of scope for template script -### how standard is this table and the levels of the variables on the current dataset + standard ADaM??? -setdiff(levels(adex$AACTPR), aact_levels) -setdiff(levels(adex$AACTDU), aact_levels) - - -# join data together -ex <- adex %>% left_join(., adsl, by = c("USUBJID")) - -### limit visits to some for testing -ex2 <- ex %>% - filter(AVISIT %in% levels(ex$AVISIT)[1:4]) %>% - mutate(AVISIT = factor(as.character(AVISIT), levels = levels(ex$AVISIT)[1:4])) - - -################################################################################ -# Define layout and build table: -################################################################################ - -colspan_trt_map <- create_colspan_map( - adsl, - non_active_grp = ctrl_grp, - non_active_grp_span_lbl = " ", - active_grp_span_lbl = "Active Study Agent", - colspan_var = "colspan_trt", - trt_var = trtvar -) -ref_path <- c("colspan_trt", " ", trtvar, ctrl_grp) - - -split_map <- tribble( - ~XXX, ~AACTx, - "Prior to infusion", "Dose reduced", - "Prior to infusion", "Infusion delayed", - "Prior to infusion", "Infusion rate decreased", - "Prior to infusion", "Infusion skipped", - "Prior to infusion", "Study agent permanently discontinued", - "During infusion", "Infusion aborted", - "During infusion", "Infusion interrupted", - "During infusion", "Infusion rate increased" -) - - -extra_args1 <- list( - .stats = "count_unique_fraction", - denom = "n_parentdf", - denom_by = "AVISIT", - drop_levels = TRUE -) - -lyt <- rtables::basic_table( - top_level_section_div = " ", - show_colcounts = TRUE, - colcount_format = "N=xx" -) %>% - split_cols_by( - "colspan_trt", - split_fun = trim_levels_to_map(map = colspan_trt_map) - ) - -if (combined_colspan_trt == TRUE) { - lyt <- lyt %>% - split_cols_by(trtvar, split_fun = mysplit) -} else { - lyt <- lyt %>% - split_cols_by(trtvar) -} - - -lyt <- lyt %>% - split_rows_by( - "AVISIT", - split_label = "Time Point", - split_fun = drop_split_levels, - label_pos = "topleft", - child_labels = "visible", - indent_mod = 0L, - section_div = c(" ") - ) %>% - split_rows_by( - "XXX", - split_fun = keep_split_levels(c( - "Prior to infusion", - "During infusion" - )), - section_div = " ", - child_labels = "visible" - ) %>% - summarize_row_groups( - "XXX", - cfun = a_freq_j, - extra_args = list(.stats = "n_df", label = "N") - ) %>% - split_rows_by( - "AACTx", - split_fun = trim_levels_to_map(map = split_map), - section_div = " " - ) %>% - summarize_row_groups("AACTx", cfun = a_freq_j, extra_args = extra_args1) %>% - analyze("AADJx", afun = a_freq_j, extra_args = extra_args1) %>% - append_topleft(" Time Relative to Infusion") %>% - append_topleft(" Modification, n (%)") - -result <- build_table(lyt, ex, alt_counts_df = adsl) - -################################################################################ -# Prune table to remove all the rows with 0 counts or no data to report across all sections -################################################################################ - -result <- prune_table(result, prune_func = prune_empty_level) - -################################################################################ -# Add titles and footnotes: -################################################################################ - -result <- set_titles(result, tab_titles) - -################################################################################ -# Convert to tbl file and output table -################################################################################ -colwidth <- c(64, 21, 21, 21, 21) - -tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, orientation = "portrait") diff --git a/tests/testthat/source_code/tsiex12.R b/tests/testthat/source_code/tsiex12.R new file mode 100644 index 00000000..f31d535c --- /dev/null +++ b/tests/testthat/source_code/tsiex12.R @@ -0,0 +1,372 @@ +library(envsetup) +library(tern) +library(dplyr) +library(rtables) +library(junco) +library(stringr) +library(tidyr) + + +################################################################################ +# Define script level parameters: +################################################################################ + +################################################################################ +# - Define output ID and file location +# - Define treatment variable used (default=TRT01A) +# - Define population flag used (default=SAFFL) +# - Choose whether or not you want to present a combined active treatment column (default=TRUE) +# - Define how to create combined treatment columns (if required) +################################################################################ + +tblid <- "TSIEX12" +fileid <- write_path(opath, tblid) +tab_titles <- list( + title = "Dummy Title", + subtitles = NULL, + main_footer = "Dummy Note: On-treatment is defined as ~{optional treatment-emergent}" +) + +trtvar <- "TRT01A" +popfl <- "SAFFL" +combined_colspan_trt <- TRUE +ctrl_grp <- "Placebo" + +# Add flexibility to choose display level: "SOC_PT" or "PT" +# "SOC_PT" : display SOC header with PT terms nested underneath +# "PT" : display PT terms directly (no SOC level) +display_level <- "SOC_PT" # Options: "SOC_PT", "PT" + + +################################################################################ +# Process Data: +################################################################################ + +adsl <- adsl_jnj |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + filter(!!rlang::sym(popfl) == "Y") |> + select(STUDYID, USUBJID, all_of(trtvar), all_of(popfl)) |> + create_colspan_var( + non_active_grp = "Placebo", + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) + + +adex1 <- adex_jnj |> + filter(!grepl("UNSCHEDULED|BASELINE|SCREENING", AVISIT, ignore.case = TRUE)) |> + mutate( + AVISIT := factor( + stringr::str_to_sentence(as.character(AVISIT)), + levels = stringr::str_to_sentence(unique(.data[["AVISIT"]])[order(unique(.data[["AVISITN"]]))]) + ) + ) + + +adex2 <- adex1 |> + mutate(AVISIT = "Overall") + + +adex_ <- bind_rows(adex1, adex2) |> + mutate(ROW_ID = row_number()) + +adex1$AVISIT <- droplevels(adex1$AVISIT) +adex_$AVISIT <- factor( + adex_$AVISIT, + levels = c("Overall", levels(adex1$AVISIT)) +) +# Reshape Data for rtables Hierarchy + +# detect existing indices dynamically +idxs <- stringr::str_extract( + names(adex_)[stringr::str_detect(names(adex_), "^ABODSYS\\d+$")], + "\\d+" +) + + +adex_not_admin <- adex_ |> + filter(ACAT2 == "Dose not administered") |> + mutate( + DOSE_MOD = "Dose not administered", + AE_FLAG = ifElse <- if_else( + AREASOC == "Adverse Event", + "Adverse event", + NA_character_ + ) + ) + +# dynamically create AE_SOCi and AE_PTi +for (i in idxs) { + soc_col <- paste0("ABODSYS", i) + pt_col <- paste0("ADECOD", i) + + ae_soc <- paste0("AE_SOC", i) + ae_pt <- paste0("AE_PT", i) + + adex_not_admin <- adex_not_admin |> + mutate( + !!ae_soc := if_else( + !is.na(AE_FLAG) & !is.na(.data[[soc_col]]) & .data[[soc_col]] != "", + .data[[soc_col]], + NA_character_ + ), + !!ae_pt := if_else( + !is.na(AE_FLAG) & !is.na(.data[[pt_col]]) & .data[[pt_col]] != "", + .data[[pt_col]], + NA_character_ + ) + ) +} + + +adex_adjusted <- adex_ |> + filter(ACAT1 == "Dose adjusted") |> + mutate( + DOSE_MOD = "Dose adjusted", + AE_FLAG = if_else( + !is.na(AADJ) & AADJ == "Adverse Event", + "Adverse event", + NA_character_ + ) + ) + + +# create AE_SOCi / AE_PTi with same column labels +for (i in idxs) { + adex_adjusted <- adex_adjusted |> + mutate( + !!paste0("AE_SOC", i) := if_else( + !is.na(AE_FLAG) & + !is.na(.data[[paste0("ABODSYS", i)]]) & + .data[[paste0("ABODSYS", i)]] != "", + .data[[paste0("ABODSYS", i)]], + NA_character_ + ), + !!paste0("AE_PT", i) := if_else( + !is.na(AE_FLAG) & + !is.na(.data[[paste0("ADECOD", i)]]) & + .data[[paste0("ADECOD", i)]] != "", + .data[[paste0("ADECOD", i)]], + NA_character_ + ) + ) +} + + +# Combine +adex_events <- bind_rows(adex_not_admin, adex_adjusted) + +soc_cols <- paste0("AE_SOC", idxs) +pt_cols <- paste0("AE_PT", idxs) + +adex_no_events <- adex_ |> + filter(!(ROW_ID %in% adex_events$ROW_ID)) |> + mutate( + DOSE_MOD = NA_character_, + AE_FLAG = NA_character_, + !!!setNames( + rep(list(NA_character_), length(c(soc_cols, pt_cols))), + c(soc_cols, pt_cols) + ) + ) + + +# Bind everything +adex_stacked <- bind_rows(adex_events, adex_no_events) |> + select(USUBJID, STUDYID, AVISIT, AVISITN, DOSE_MOD, AE_FLAG, starts_with("AE_SOC"), starts_with("AE_PT")) + + +adex_stacked <- adex_stacked |> + mutate( + DOSE_MOD = factor( + DOSE_MOD, + levels = c("Dose not administered", "Dose adjusted") + ), + AE_FLAG = factor( + AE_FLAG, + levels = c("Adverse event") + ), + across(starts_with("AE_SOC"), factor), + across(starts_with("AE_PT"), factor) + ) + +adex_stacked <- adex_stacked |> + tidyr::pivot_longer( + cols = matches("^AE_(SOC|PT)\\d+$"), + names_to = c(".value", "IDX"), + names_pattern = "AE_(SOC|PT)(\\d+)" + ) |> + mutate( + SOC = as.factor(stringr::str_to_sentence(SOC)), + PT = as.factor(stringr::str_to_sentence(PT)) + ) + + +# Join +ex <- adex_stacked |> left_join(adsl, by = c("USUBJID", "STUDYID")) + +# Auto-detect: if all SOC values are NA, fall back to PT only +if (all(is.na(ex$SOC))) { + display_level <- "PT" +} + +################################################################################ +# Define layout and build table: +################################################################################ + +colspan_trt_map <- create_colspan_map( + adsl, + non_active_grp = ctrl_grp, + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar +) + +split_combined <- if (combined_colspan_trt) { + add_combo <- add_combo_facet( + "Combined", + label = "Combined", + levels = setdiff(levels(adsl[[trtvar]]), ctrl_grp) + ) + rm_combo_from_placebo <- cond_rm_facets( + facets = "Combined", + ancestor_pos = NA, + value = " ", + split = "colspan_trt" + ) + make_split_fun(post = list(add_combo, rm_combo_from_placebo)) +} else { + NULL +} + +extra_args1 <- list( + .stats = "count_unique_fraction", + denom = "n_parentdf", + denom_by = "AVISIT" +) + +lyt <- rtables::basic_table( + top_level_section_div = " ", + show_colcounts = TRUE, + colcount_format = "N=xx" +) |> + split_cols_by( + "colspan_trt", + split_fun = trim_levels_to_map(map = colspan_trt_map) + ) |> + split_cols_by(trtvar, split_fun = split_combined) |> + # Hierarchy Level 1: Time Point + split_rows_by( + "AVISIT", + split_label = "Time Point", + label_pos = "topleft", + indent_mod = 0L, + section_div = " " + ) |> + summarize_row_groups( + "AVISIT", + cfun = a_freq_j, + extra_args = list(.stats = "n_df"), + indent_mod = 0L + ) |> + split_rows_by( + "DOSE_MOD", + split_label = "Dose Modification", + label_pos = "topleft", + indent_mod = 0L + ) |> + summarize_row_groups( + "DOSE_MOD", + cfun = a_freq_j, + extra_args = extra_args1, + indent_mod = 0L + ) |> + split_rows_by( + "AE_FLAG", + indent_mod = 0L, + child_labels = "hidden", + split_fun = keep_split_levels("Adverse event") + ) + +if (display_level == "SOC_PT") { + lyt <- lyt |> + analyze( + vars = "AE_FLAG", + afun = a_three_tier, + indent_mod = 0L, + extra_args = c( + extra_args1, + list( + grp_fun = a_freq_j, + detail_fun = a_freq_j, + inner_var1 = "SOC", + inner_var2 = "PT", + drill_down_levs = "Adverse event", + use_all_levels = FALSE + ) + ) + ) |> + append_topleft(c(" System Organ Class")) |> + append_topleft(c(" Preferred Term, n (%)")) +} else if (display_level == "PT") { + lyt <- lyt |> + analyze( + vars = "AE_FLAG", + afun = a_two_tier, + indent_mod = 0L, + extra_args = c( + extra_args1, + list( + grp_fun = a_freq_j, + detail_fun = a_freq_j, + inner_var = "PT", + drill_down_levs = "Adverse event", + use_all_levels = FALSE + ) + ) + ) |> + append_topleft(c(" Preferred Term, n (%)")) +} + +result <- build_table(lyt, ex, alt_counts_df = adsl, round_type = "sas") + + +################################################################################ +# Add titles and footnotes: +################################################################################ + +result <- set_titles(result, tab_titles) + +# derivation of number of rows column header takes +cps <- col_paths(result)[[1]] +cps <- cps[seq(from = 1, by = 2, length.out = length(cps) / 2)] +### as showcolcounts = TRUE, 1 extra row in columns +levels_cols <- length(cps) + 1 + +bordmat <- junco:::make_header_bordmat(obj = result) +if (levels_cols < length(top_left(result))) { + extra_row <- rep(0, ncol(bordmat)) + bordmat <- rbind(extra_row, bordmat) + rownames(bordmat) <- NULL +} + +################################################################################ +# Convert to tbl file and output table +################################################################################ + + +colwidth <- c(64, 21, 21, 21, 21) + +tt_to_tlgrtf(colwidths = colwidth, result, file = fileid, border_mat = bordmat, orientation = "portrait") diff --git a/tests/testthat/source_code/tsimh01.R b/tests/testthat/source_code/tsimh01.R index bf8c27d8..1535c672 100644 --- a/tests/testthat/source_code/tsimh01.R +++ b/tests/testthat/source_code/tsimh01.R @@ -1,27 +1,3 @@ -################################################################################ -## Original Reporting Effort: Standards -## Program Name: tsimh01 -## R version: 4.2.1 -## Short Description: Program to create tsimh01: [Medical History/Medical History of Interest] by -## System Organ Class and Preferred Term -## Author: Johnson & Johnson Innovative Medicine -## Date: 30JAN2024 -## Input: adsl.RDS, mh.sas7bdat -## Output: tsimh01.rtf -## Remarks: -## -## Modification History: -## Rev #: -## Modified By: -## Reporting Effort: -## Date: -## Description: -################################################################################ - -################################################################################ -# Prep environment: -################################################################################ - library(envsetup) library(tern) library(dplyr) @@ -41,62 +17,66 @@ titles <- list( ) popfls <- c("FASFL", "SAFFL") popfl <- popfls[1] -trtvar <- "TRT01P" +trtvar <- "TRT01A" ctrl_grp <- "Placebo" -table_vars <- c("MHOCCUR", "MHCAT", "MHBODSYS", "MHDECOD", "MHENRTPT", "MHTERM") +table_vars <- c("MHOCCUR", "MHCAT", "MHBODSYS", "MHDECOD", "MHTERM") + +# Add flexibility to choose display level: "SOC", "PT", or "BOTH" +display_level <- "BOTH" # Options: "SOC", "PT", "BOTH" ################################################################################ # Process data: ################################################################################ -adsl <- adsl_jnj %>% - filter(.data[[popfl]] == "Y") %>% - select(STUDYID, USUBJID, all_of(popfls), starts_with("TRT01")) - -mh <- mh_jnj - -if (!("MHOCCUR" %in% names(mh))) { - ## add missing MHOCCUR variable for now - mh$MHOCCUR <- "Y" -} +adsl <- adsl_jnj |> + filter(.data[[popfl]] == "Y") |> + mutate( + !!rlang::sym(trtvar) := factor( + .data[[trtvar]], + levels = c( + "Xanomeline Low Dose", + "Xanomeline High Dose", + "Placebo" + ) + ) + ) |> + select(STUDYID, USUBJID, all_of(popfls), all_of(trtvar)) |> + create_colspan_var( + non_active_grp = "Placebo", + non_active_grp_span_lbl = " ", + active_grp_span_lbl = "Active Study Agent", + colspan_var = "colspan_trt", + trt_var = trtvar + ) -mh <- mh %>% select(all_of(c("USUBJID", table_vars))) +mh <- mh_jnj |> + select(all_of(c("USUBJID", table_vars))) |> + # user can filter appropriate value of MHCAT for medical histrory of intreset. + filter(MHOCCUR == "Y" & stringr::str_to_upper(MHCAT) == "GENERAL MEDICAL HISTORY") -## define formats - most could be removed if we could start from metadata-enhanced rds dataset +mh[table_vars] <- lapply(mh[table_vars], stringr::str_to_sentence) -mh <- mh %>% +mh <- mh |> mutate( MHDECOD = factor(case_when( - MHDECOD == "" ~ paste0("Uncoded: ", MHTERM), + MHDECOD == "" | is.na(MHDECOD) ~ paste0("Uncoded: ", MHTERM), .default = MHDECOD )), MHBODSYS = factor(case_when( - MHBODSYS == "" ~ "Uncoded", + MHBODSYS == "" | is.na(MHBODSYS) ~ "Uncoded", .default = MHBODSYS )) ) -### restrict to mh -### here : use MHENRTPT for ONGOING - -mh <- mh %>% - filter(MHENRTPT == "ONGOING") - -adsl$colspan_trt <- factor( - ifelse(adsl[[trtvar]] == ctrl_grp, " ", "Active Study Agent"), - levels = c("Active Study Agent", " ") -) - - -mh <- mh %>% inner_join(., adsl, by = c("USUBJID")) +mh <- mh |> inner_join(adsl, by = c("USUBJID")) ## update label genmh_label to match selection that has been made -genmh_label <- "Subjects with ≥1 medical history" +genmh_label <- "Subjects with >=1 medical history" -genmh_label <- "Subjects with ≥1 ongoing medical history" - -## genmh_label <- "Subjects with ≥1 medical history of interest" # when a different selection is made +################################################################################ +# Define layout and build table: +################################################################################ colspan_trt_map <- create_colspan_map( adsl, @@ -107,64 +87,79 @@ colspan_trt_map <- create_colspan_map( trt_var = trtvar ) -################################################################################ -# Define layout and build table: -################################################################################ - -split_fun <- drop_split_levels - -countfraction_subjects <- function(df, labelstr, .var, .N_col, id = "USUBJID") { - nsub <- length(unique(df[[id]])) - denom <- .N_col - count_fraction <- c(nsub, nsub / denom) - - ret <- in_rows( - count_fraction, - .formats = jjcsformat_count_fraction, - .labels = sprintf(labelstr) - ) - - return(ret) -} +extra_args1 <- list( + .stats = "count_unique_fraction", + denom = "n_altdf" +) +# Build base layout lyt <- basic_table( show_colcounts = TRUE, colcount_format = "N=xx", top_level_section_div = " " -) %>% +) |> split_cols_by( "colspan_trt", split_fun = trim_levels_to_map(map = colspan_trt_map) - ) %>% - split_cols_by(trtvar) %>% - add_overall_col("Total") %>% + ) |> + split_cols_by(trtvar) |> + add_overall_col("Total") |> analyze( "MHOCCUR", - var_labels = "Total number of cycles received, n (%)", afun = a_freq_j, extra_args = list( label = genmh_label, .stats = c("count_unique_fraction") ), - show_labels = "hidden" - ) %>% - split_rows_by( - "MHBODSYS", - split_label = "System Organ Class", - split_fun = trim_levels_in_group("MHDECOD"), - label_pos = "topleft", - section_div = c(" ") - ) %>% - ### ensure to utilize a cfun that counts unique subjects - summarize_row_groups("MHBODSYS", cfun = countfraction_subjects) %>% - count_occurrences( - "MHDECOD", - .stats = c("count_fraction"), - .formats = c("count_fraction" = jjcsformat_count_fraction) - ) %>% - append_topleft(" Preferred Term, n (%)") - -result <- build_table(lyt, mh, alt_counts_df = adsl) + show_labels = "hidden", + section_div = "" + ) + +# Add SOC and/or PT based on display_level parameter +if (display_level == "BOTH") { + lyt <- lyt |> + split_rows_by( + "MHBODSYS", + split_label = "System Organ Class", + split_fun = trim_levels_in_group("MHDECOD"), + label_pos = "topleft", + section_div = c(" ") + ) |> + summarize_row_groups( + "MHBODSYS", + cfun = a_freq_j, + extra_args = extra_args1 + ) |> + analyze( + "MHDECOD", + afun = a_freq_j, + extra_args = extra_args1, + indent_mod = 0L, + show_labels = "hidden", + nested = TRUE + ) |> + append_topleft(" Preferred Term, n (%)") +} else if (display_level == "SOC") { + lyt <- lyt |> + analyze( + "MHBODSYS", + afun = a_freq_j, + extra_args = extra_args1, + show_labels = "hidden", + ) |> + append_topleft(" System Organ Class, n (%)") +} else if (display_level == "PT") { + lyt <- lyt |> + analyze( + "MHDECOD", + afun = a_freq_j, + extra_args = extra_args1, + show_labels = "hidden", + ) |> + append_topleft(" Preferred Term, n (%)") +} + +result <- build_table(lyt, mh, alt_counts_df = adsl, round_type = "sas") ################################################################################ # Post-Processing: @@ -172,16 +167,32 @@ result <- build_table(lyt, mh, alt_counts_df = adsl) # or active treatment columns if it does not ################################################################################ -result <- sort_at_path( - result, - c("root", "MHBODSYS"), - scorefun = jj_complex_scorefun("Total") -) -result <- sort_at_path( - result, - c("root", "MHBODSYS", "*", "MHDECOD"), - scorefun = jj_complex_scorefun("Total") -) +# Apply sorting based on display_level +if (display_level == "BOTH") { + result <- sort_at_path( + result, + c("root", "MHBODSYS"), + scorefun = jj_complex_scorefun("Total") + ) + result <- sort_at_path( + result, + c("root", "MHBODSYS", "*", "MHDECOD"), + scorefun = jj_complex_scorefun("Total") + ) +} else if (display_level == "SOC") { + result <- sort_at_path( + result, + c("root", "MHBODSYS"), + scorefun = jj_complex_scorefun("Total") + ) +} else if (display_level == "PT") { + result <- sort_at_path( + result, + c("root", "MHDECOD"), + scorefun = jj_complex_scorefun("Total") + ) +} + ################################################################################ # Add titles and footnotes: @@ -193,6 +204,7 @@ result <- set_titles(result, titles) # Convert to tbl file and output table: ################################################################################ -colwidth <- c(64, 17, 17, 17, 17) + +colwidth <- c(64, 21, 21, 21, 23) tt_to_tlgrtf(colwidths = colwidth, result, fileid) diff --git a/tests/testthat/test-lirada01.R b/tests/testthat/test-lirada01.R new file mode 100644 index 00000000..85d212c5 --- /dev/null +++ b/tests/testthat/test-lirada01.R @@ -0,0 +1,5 @@ +test_that("lirada01", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lirada01.R", rtf_name = "lirada01.rtf"), "lirada01.rtf") +}) diff --git a/tests/testthat/test-lirada02.R b/tests/testthat/test-lirada02.R new file mode 100644 index 00000000..cb816b1e --- /dev/null +++ b/tests/testthat/test-lirada02.R @@ -0,0 +1,5 @@ +test_that("lirada02", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lirada02.R", rtf_name = "lirada02.rtf"), "lirada02.rtf") +}) diff --git a/tests/testthat/test-lirada03.R b/tests/testthat/test-lirada03.R new file mode 100644 index 00000000..6a278034 --- /dev/null +++ b/tests/testthat/test-lirada03.R @@ -0,0 +1,5 @@ +test_that("lirada03", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lirada03.R", rtf_name = "lirada03.rtf"), "lirada03.rtf") +}) diff --git a/tests/testthat/test-lirada04.R b/tests/testthat/test-lirada04.R new file mode 100644 index 00000000..79f1af90 --- /dev/null +++ b/tests/testthat/test-lirada04.R @@ -0,0 +1,5 @@ +test_that("lirada04", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lirada04.R", rtf_name = "lirada04.rtf"), "lirada04.rtf") +}) diff --git a/tests/testthat/test-lirada05.R b/tests/testthat/test-lirada05.R new file mode 100644 index 00000000..57d0639e --- /dev/null +++ b/tests/testthat/test-lirada05.R @@ -0,0 +1,5 @@ +test_that("lirada05", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lirada05.R", rtf_name = "lirada05.rtf"), "lirada05.rtf") +}) diff --git a/tests/testthat/test-lpk01.R b/tests/testthat/test-lpk01.R new file mode 100644 index 00000000..3e541371 --- /dev/null +++ b/tests/testthat/test-lpk01.R @@ -0,0 +1,5 @@ +test_that("lpk01", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lpk01.R"), "lpk01.rtf") +}) diff --git a/tests/testthat/test-lsfae05b.R b/tests/testthat/test-lsfae05b.R new file mode 100644 index 00000000..83b47d01 --- /dev/null +++ b/tests/testthat/test-lsfae05b.R @@ -0,0 +1,5 @@ +test_that("lsfae05b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lsfae05b.R"), "lsfae05b.rtf") +}) diff --git a/tests/testthat/test-lsfae06.R b/tests/testthat/test-lsfae06.R new file mode 100644 index 00000000..92fe92e3 --- /dev/null +++ b/tests/testthat/test-lsfae06.R @@ -0,0 +1,5 @@ +test_that("lsfae06", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lsfae06.R"), "lsfae06.rtf") +}) diff --git a/tests/testthat/test-lsfae06a.R b/tests/testthat/test-lsfae06a.R deleted file mode 100644 index 601319ab..00000000 --- a/tests/testthat/test-lsfae06a.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("lsfae06a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("lsfae06a.R"), "lsfae06a.rtf") -}) diff --git a/tests/testthat/test-lsfae06b.R b/tests/testthat/test-lsfae06b.R deleted file mode 100644 index eb8db36d..00000000 --- a/tests/testthat/test-lsfae06b.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("lsfae06b", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("lsfae06b.R"), "lsfae06b.rtf") -}) diff --git a/tests/testthat/test-lsfecg02.R b/tests/testthat/test-lsfecg02.R new file mode 100644 index 00000000..cb6f9c7b --- /dev/null +++ b/tests/testthat/test-lsfecg02.R @@ -0,0 +1,5 @@ +test_that("lsfecg02", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lsfecg02.R"), "lsfecg02.rtf") +}) diff --git a/tests/testthat/test-lsfecg02part1.R b/tests/testthat/test-lsfecg02part1.R deleted file mode 100644 index 9059b82b..00000000 --- a/tests/testthat/test-lsfecg02part1.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("lsfecg02part1of3", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("lsfecg02.R", part_num = 1, total_parts = 3), "lsfecg02part1of3.rtf") -}) diff --git a/tests/testthat/test-lsfecg02part2.R b/tests/testthat/test-lsfecg02part2.R deleted file mode 100644 index 35d69cec..00000000 --- a/tests/testthat/test-lsfecg02part2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("lsfecg02part2of3", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("lsfecg02.R", part_num = 2, total_parts = 3), "lsfecg02part2of3.rtf") -}) diff --git a/tests/testthat/test-lsfecg02part3.R b/tests/testthat/test-lsfecg02part3.R deleted file mode 100644 index 104c2793..00000000 --- a/tests/testthat/test-lsfecg02part3.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("lsfecg02part3of3", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("lsfecg02.R", part_num = 3, total_parts = 3), "lsfecg02part3of3.rtf") -}) diff --git a/tests/testthat/test-lsflab02.R b/tests/testthat/test-lsflab02.R new file mode 100644 index 00000000..96d4b51a --- /dev/null +++ b/tests/testthat/test-lsflab02.R @@ -0,0 +1,5 @@ +test_that("lsflab02", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lsflab02.R"), "lsflab02.rtf") +}) diff --git a/tests/testthat/test-lsidev01.R b/tests/testthat/test-lsidev01.R new file mode 100644 index 00000000..a39f71f6 --- /dev/null +++ b/tests/testthat/test-lsidev01.R @@ -0,0 +1,5 @@ +test_that("lsidev01", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lsidev01.R"), "lsidev01.rtf") +}) diff --git a/tests/testthat/test-lsidev02.R b/tests/testthat/test-lsidev02.R new file mode 100644 index 00000000..d6fa2d23 --- /dev/null +++ b/tests/testthat/test-lsidev02.R @@ -0,0 +1,5 @@ +test_that("lsidev02", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lsidev02.R"), "lsidev02.rtf") +}) diff --git a/tests/testthat/test-lsidev03.R b/tests/testthat/test-lsidev03.R new file mode 100644 index 00000000..84dc41f2 --- /dev/null +++ b/tests/testthat/test-lsidev03.R @@ -0,0 +1,5 @@ +test_that("lsidev03", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lsidev03.R"), "lsidev03.rtf") +}) diff --git a/tests/testthat/test-lsiex04.R b/tests/testthat/test-lsiex04.R new file mode 100644 index 00000000..ed9dbe6c --- /dev/null +++ b/tests/testthat/test-lsiex04.R @@ -0,0 +1,5 @@ +test_that("lsiex04", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("lsiex04.R"), "lsiex04.rtf") +}) diff --git a/tests/testthat/test-tirada01.R b/tests/testthat/test-tirada01.R new file mode 100644 index 00000000..7b4df6a2 --- /dev/null +++ b/tests/testthat/test-tirada01.R @@ -0,0 +1,5 @@ +test_that("tirada01", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirada01.R", rtf_name = "tirada01.rtf"), "tirada01.rtf") +}) diff --git a/tests/testthat/test-tirada02.R b/tests/testthat/test-tirada02.R new file mode 100644 index 00000000..96f0a093 --- /dev/null +++ b/tests/testthat/test-tirada02.R @@ -0,0 +1,5 @@ +test_that("tirada02", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirada02.R", rtf_name = "tirada02.rtf"), "tirada02.rtf") +}) diff --git a/tests/testthat/test-tirada02b.R b/tests/testthat/test-tirada02b.R new file mode 100644 index 00000000..c726cbfd --- /dev/null +++ b/tests/testthat/test-tirada02b.R @@ -0,0 +1,5 @@ +test_that("tirada02b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirada02b.R", rtf_name = "tirada02b.rtf"), "tirada02b.rtf") +}) diff --git a/tests/testthat/test-tirada02btiter.R b/tests/testthat/test-tirada02btiter.R new file mode 100644 index 00000000..008de486 --- /dev/null +++ b/tests/testthat/test-tirada02btiter.R @@ -0,0 +1,5 @@ +test_that("tirada02btiter", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirada02btiter.R", rtf_name = "tirada02btiter.rtf"), "tirada02btiter.rtf") +}) diff --git a/tests/testthat/test-tirada02titer.R b/tests/testthat/test-tirada02titer.R new file mode 100644 index 00000000..17a55f84 --- /dev/null +++ b/tests/testthat/test-tirada02titer.R @@ -0,0 +1,5 @@ +test_that("tirada02titer", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirada02titer.R", rtf_name = "tirada02titer.rtf"), "tirada02titer.rtf") +}) diff --git a/tests/testthat/test-tirada03.R b/tests/testthat/test-tirada03.R new file mode 100644 index 00000000..e14f523b --- /dev/null +++ b/tests/testthat/test-tirada03.R @@ -0,0 +1,5 @@ +test_that("tirada03", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirada03.R", rtf_name = "tirada03.rtf"), "tirada03.rtf") +}) diff --git a/tests/testthat/test-tirada03titer.R b/tests/testthat/test-tirada03titer.R new file mode 100644 index 00000000..e16f7beb --- /dev/null +++ b/tests/testthat/test-tirada03titer.R @@ -0,0 +1,5 @@ +test_that("tirada03titer", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirada03titer.R", rtf_name = "tirada03titer.rtf"), "tirada03titer.rtf") +}) diff --git a/tests/testthat/test-tirada06.R b/tests/testthat/test-tirada06.R new file mode 100644 index 00000000..ca9b3235 --- /dev/null +++ b/tests/testthat/test-tirada06.R @@ -0,0 +1,5 @@ +test_that("tirada06", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirada06.R", rtf_name = "tirada06.rtf"), "tirada06.rtf") +}) diff --git a/tests/testthat/test-tirada07.R b/tests/testthat/test-tirada07.R new file mode 100644 index 00000000..2c07ce27 --- /dev/null +++ b/tests/testthat/test-tirada07.R @@ -0,0 +1,5 @@ +test_that("tirada07", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirada07.R", rtf_name = "tirada07.rtf"), "tirada07.rtf") +}) diff --git a/tests/testthat/test-tirnab01.R b/tests/testthat/test-tirnab01.R new file mode 100644 index 00000000..894c13ca --- /dev/null +++ b/tests/testthat/test-tirnab01.R @@ -0,0 +1,5 @@ +test_that("tirnab01", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirnab01.R", rtf_name = "tirnab01.rtf"), "tirnab01.rtf") +}) diff --git a/tests/testthat/test-tirnab02.R b/tests/testthat/test-tirnab02.R new file mode 100644 index 00000000..04c29359 --- /dev/null +++ b/tests/testthat/test-tirnab02.R @@ -0,0 +1,5 @@ +test_that("tirnab02", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirnab02.R", rtf_name = "tirnab02.rtf"), "tirnab02.rtf") +}) diff --git a/tests/testthat/test-tirnab03.R b/tests/testthat/test-tirnab03.R new file mode 100644 index 00000000..f2155afb --- /dev/null +++ b/tests/testthat/test-tirnab03.R @@ -0,0 +1,5 @@ +test_that("tirnab03", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tirnab03.R", rtf_name = "tirnab03.rtf"), "tirnab03.rtf") +}) diff --git a/tests/testthat/test-tpk01bpart1.R b/tests/testthat/test-tpk01b.R similarity index 57% rename from tests/testthat/test-tpk01bpart1.R rename to tests/testthat/test-tpk01b.R index e4fb4d4a..2d4d438f 100644 --- a/tests/testthat/test-tpk01bpart1.R +++ b/tests/testthat/test-tpk01b.R @@ -1,5 +1,4 @@ -test_that("tpk01bpart1of2", { +test_that("tpk01b", { skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tpk01b.R", part_num = 1, total_parts = 2), "tpk01bpart1of2.rtf") + expect_snapshot_file(write_test_rtf_for("tpk01b.R", part_num = 1, total_parts = 2), "tpk01part1of2.rtf") }) diff --git a/tests/testthat/test-tpk01bpart2.R b/tests/testthat/test-tpk01bpart2.R deleted file mode 100644 index fef089ef..00000000 --- a/tests/testthat/test-tpk01bpart2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tpk01bpart2of2", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tpk01b.R", part_num = 2, total_parts = 2), "tpk01bpart2of2.rtf") -}) diff --git a/tests/testthat/test-tpk02part1.R b/tests/testthat/test-tpk02.R similarity index 82% rename from tests/testthat/test-tpk02part1.R rename to tests/testthat/test-tpk02.R index 59811081..f2e48ebf 100644 --- a/tests/testthat/test-tpk02part1.R +++ b/tests/testthat/test-tpk02.R @@ -1,5 +1,4 @@ -test_that("tpk02part1of2", { +test_that("tpk02", { skip_if_not_installed("envsetup") - expect_snapshot_file(write_test_rtf_for("tpk02.R", part_num = 1, total_parts = 2), "tpk02part1of2.rtf") }) diff --git a/tests/testthat/test-tpk02part2.R b/tests/testthat/test-tpk02part2.R deleted file mode 100644 index c3faf167..00000000 --- a/tests/testthat/test-tpk02part2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tpk02part2of2", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tpk02.R", part_num = 2, total_parts = 2), "tpk02part2of2.rtf") -}) diff --git a/tests/testthat/test-tpkada01.R b/tests/testthat/test-tpkada01.R new file mode 100644 index 00000000..eceeb37f --- /dev/null +++ b/tests/testthat/test-tpkada01.R @@ -0,0 +1,5 @@ +test_that("tpkada01", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tpkada01.R"), "tpkada01.rtf") +}) diff --git a/tests/testthat/test-tpkada01titer.R b/tests/testthat/test-tpkada01titer.R new file mode 100644 index 00000000..2523a142 --- /dev/null +++ b/tests/testthat/test-tpkada01titer.R @@ -0,0 +1,5 @@ +test_that("tpkada01titer", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tpkada01titer.R", rtf_name = "tpkada01titer.rtf"), "tpkada01titer.rtf") +}) diff --git a/tests/testthat/test-tsfae03.R b/tests/testthat/test-tsfae03.R deleted file mode 100644 index 030b44e1..00000000 --- a/tests/testthat/test-tsfae03.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae03", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae03.R"), "tsfae03.rtf") -}) diff --git a/tests/testthat/test-tsfae03b.R b/tests/testthat/test-tsfae03b.R new file mode 100644 index 00000000..d41be6f9 --- /dev/null +++ b/tests/testthat/test-tsfae03b.R @@ -0,0 +1,5 @@ +test_that("tsfae03b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae03b.R"), "tsfae03b.rtf") +}) diff --git a/tests/testthat/test-tsfae03c.R b/tests/testthat/test-tsfae03c.R new file mode 100644 index 00000000..c0249c81 --- /dev/null +++ b/tests/testthat/test-tsfae03c.R @@ -0,0 +1,5 @@ +test_that("tsfae03c", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae03c.R"), "tsfae03c.rtf") +}) diff --git a/tests/testthat/test-tsfae03d.R b/tests/testthat/test-tsfae03d.R new file mode 100644 index 00000000..fafdc2d6 --- /dev/null +++ b/tests/testthat/test-tsfae03d.R @@ -0,0 +1,5 @@ +test_that("tsfae03d", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae03d.R"), "tsfae03d.rtf") +}) diff --git a/tests/testthat/test-tsfae03e.R b/tests/testthat/test-tsfae03e.R new file mode 100644 index 00000000..f7beb824 --- /dev/null +++ b/tests/testthat/test-tsfae03e.R @@ -0,0 +1,5 @@ +test_that("tsfae03e", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae03e.R"), "tsfae03e.rtf") +}) diff --git a/tests/testthat/test-tsfae03f.R b/tests/testthat/test-tsfae03f.R new file mode 100644 index 00000000..11547153 --- /dev/null +++ b/tests/testthat/test-tsfae03f.R @@ -0,0 +1,5 @@ +test_that("tsfae03f", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae03f.R"), "tsfae03f.rtf") +}) diff --git a/tests/testthat/test-tsfae04.R b/tests/testthat/test-tsfae04.R deleted file mode 100644 index 3c312655..00000000 --- a/tests/testthat/test-tsfae04.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae04", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae04.R"), "tsfae04.rtf") -}) diff --git a/tests/testthat/test-tsfae04b.R b/tests/testthat/test-tsfae04b.R new file mode 100644 index 00000000..8eeacd15 --- /dev/null +++ b/tests/testthat/test-tsfae04b.R @@ -0,0 +1,5 @@ +test_that("tsfae04b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae04b.R"), "tsfae04b.rtf") +}) diff --git a/tests/testthat/test-tsfae04c.R b/tests/testthat/test-tsfae04c.R new file mode 100644 index 00000000..e122ec49 --- /dev/null +++ b/tests/testthat/test-tsfae04c.R @@ -0,0 +1,5 @@ +test_that("tsfae04c", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae04c.R"), "tsfae04c.rtf") +}) diff --git a/tests/testthat/test-tsfae05a.R b/tests/testthat/test-tsfae05a.R deleted file mode 100644 index db0133cc..00000000 --- a/tests/testthat/test-tsfae05a.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae05a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae05a.R"), "tsfae05a.rtf") -}) diff --git a/tests/testthat/test-tsfae06.R b/tests/testthat/test-tsfae06.R new file mode 100644 index 00000000..652a781b --- /dev/null +++ b/tests/testthat/test-tsfae06.R @@ -0,0 +1,5 @@ +test_that("tsfae06", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae06.R"), "tsfae06.rtf") +}) diff --git a/tests/testthat/test-tsfae06a.R b/tests/testthat/test-tsfae06a.R deleted file mode 100644 index 5b85f1f9..00000000 --- a/tests/testthat/test-tsfae06a.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae06a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae06a.R"), "tsfae06a.rtf") -}) diff --git a/tests/testthat/test-tsfae06b.R b/tests/testthat/test-tsfae06b.R deleted file mode 100644 index 014d6d35..00000000 --- a/tests/testthat/test-tsfae06b.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae06b", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae06b.R"), "tsfae06b.rtf") -}) diff --git a/tests/testthat/test-tsfae07c.R b/tests/testthat/test-tsfae07c.R new file mode 100644 index 00000000..54089736 --- /dev/null +++ b/tests/testthat/test-tsfae07c.R @@ -0,0 +1,5 @@ +test_that("tsfae07c", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae07c.R"), "tsfae07c.rtf") +}) diff --git a/tests/testthat/test-tsfae07d.R b/tests/testthat/test-tsfae07d.R new file mode 100644 index 00000000..5afe3f84 --- /dev/null +++ b/tests/testthat/test-tsfae07d.R @@ -0,0 +1,5 @@ +test_that("tsfae07d", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae07d.R"), "tsfae07d.rtf") +}) diff --git a/tests/testthat/test-tsfae07e.R b/tests/testthat/test-tsfae07e.R new file mode 100644 index 00000000..14b5171d --- /dev/null +++ b/tests/testthat/test-tsfae07e.R @@ -0,0 +1,5 @@ +test_that("tsfae07e", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae07e.R"), "tsfae07e.rtf") +}) diff --git a/tests/testthat/test-tsfae10.R b/tests/testthat/test-tsfae10.R deleted file mode 100644 index d09a74e8..00000000 --- a/tests/testthat/test-tsfae10.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae10", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae10.R"), "tsfae10.rtf") -}) diff --git a/tests/testthat/test-tsfae10a.R b/tests/testthat/test-tsfae10a.R new file mode 100644 index 00000000..8555c54e --- /dev/null +++ b/tests/testthat/test-tsfae10a.R @@ -0,0 +1,5 @@ +test_that("tsfae10a", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae10a.R"), "tsfae10a.rtf") +}) diff --git a/tests/testthat/test-tsfae10b.R b/tests/testthat/test-tsfae10b.R new file mode 100644 index 00000000..e98c42c6 --- /dev/null +++ b/tests/testthat/test-tsfae10b.R @@ -0,0 +1,5 @@ +test_that("tsfae10b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae10b.R"), "tsfae10b.rtf") +}) diff --git a/tests/testthat/test-tsfae10c.R b/tests/testthat/test-tsfae10c.R new file mode 100644 index 00000000..73125a8d --- /dev/null +++ b/tests/testthat/test-tsfae10c.R @@ -0,0 +1,5 @@ +test_that("tsfae10c", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae10c.R"), "tsfae10c.rtf") +}) diff --git a/tests/testthat/test-tsfae11.R b/tests/testthat/test-tsfae11.R deleted file mode 100644 index cc8b97b8..00000000 --- a/tests/testthat/test-tsfae11.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae11", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae11.R"), "tsfae11.rtf") -}) diff --git a/tests/testthat/test-tsfae11a.R b/tests/testthat/test-tsfae11a.R new file mode 100644 index 00000000..611e5b29 --- /dev/null +++ b/tests/testthat/test-tsfae11a.R @@ -0,0 +1,11 @@ +test_that("tsfae11apart1of2", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae11a.R", part_num = 1, total_parts = 2), "tsfae11apart1of2.rtf") +}) + +# test_that("tsfae11apart2of2", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae11a.R", part_num = 2, total_parts = 2), "tsfae11apart2of2.rtf") +# }) diff --git a/tests/testthat/test-tsfae11b.R b/tests/testthat/test-tsfae11b.R new file mode 100644 index 00000000..a4617027 --- /dev/null +++ b/tests/testthat/test-tsfae11b.R @@ -0,0 +1,23 @@ +test_that("tsfae11bpart1of4", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae11b.R", part_num = 1, total_parts = 4), "tsfae11bpart1of4.rtf") +}) + +# test_that("tsfae11bpart2of4", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae11b.R", part_num = 2, total_parts = 4), "tsfae11bpart2of4.rtf") +# }) + +# test_that("tsfae11bpart3of4", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae11b.R", part_num = 3, total_parts = 4), "tsfae11bpart3of4.rtf") +# }) + +# test_that("tsfae11bpart4of4", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae11b.R", part_num = 4, total_parts = 4), "tsfae11bpart4of4.rtf") +# }) diff --git a/tests/testthat/test-tsfae11c.R b/tests/testthat/test-tsfae11c.R new file mode 100644 index 00000000..186be748 --- /dev/null +++ b/tests/testthat/test-tsfae11c.R @@ -0,0 +1,5 @@ +test_that("tsfae11c", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae11c.R"), "tsfae11c.rtf") +}) diff --git a/tests/testthat/test-tsfae11d.R b/tests/testthat/test-tsfae11d.R new file mode 100644 index 00000000..5cae2f12 --- /dev/null +++ b/tests/testthat/test-tsfae11d.R @@ -0,0 +1,5 @@ +test_that("tsfae11d", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae11d.R"), "tsfae11d.rtf") +}) diff --git a/tests/testthat/test-tsfae12.R b/tests/testthat/test-tsfae12.R deleted file mode 100644 index f72de773..00000000 --- a/tests/testthat/test-tsfae12.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae12", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae12.R"), "tsfae12.rtf") -}) diff --git a/tests/testthat/test-tsfae12a.R b/tests/testthat/test-tsfae12a.R new file mode 100644 index 00000000..cf8b689f --- /dev/null +++ b/tests/testthat/test-tsfae12a.R @@ -0,0 +1,23 @@ +test_that("tsfae12apart1of4", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae12a.R", part_num = 1, total_parts = 4), "tsfae12apart1of4.rtf") +}) + +# test_that("tsfae12apart2of4", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae12a.R", part_num = 2, total_parts = 4), "tsfae12apart2of4.rtf") +# }) + +# test_that("tsfae12apart3of4", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae12a.R", part_num = 3, total_parts = 4), "tsfae12apart3of4.rtf") +# }) + +# test_that("tsfae12apart4of4", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae12a.R", part_num = 4, total_parts = 4), "tsfae12apart4of4.rtf") +# }) diff --git a/tests/testthat/test-tsfae12b.R b/tests/testthat/test-tsfae12b.R new file mode 100644 index 00000000..5aa2e4e9 --- /dev/null +++ b/tests/testthat/test-tsfae12b.R @@ -0,0 +1,11 @@ +test_that("tsfae12bpart1of2", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae12b.R", part_num = 1, total_parts = 2), "tsfae12bpart1of2.rtf") +}) + +# test_that("tsfae12bpart2of2", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae12b.R", part_num = 2, total_parts = 2), "tsfae12bpart2of2.rtf") +# }) diff --git a/tests/testthat/test-tsfae12c.R b/tests/testthat/test-tsfae12c.R new file mode 100644 index 00000000..4fc4a04a --- /dev/null +++ b/tests/testthat/test-tsfae12c.R @@ -0,0 +1,23 @@ +test_that("tsfae12cpart1of4", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae12c.R", part_num = 1, total_parts = 4), "tsfae12cpart1of4.rtf") +}) + +# test_that("tsfae12cpart2of4", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae12c.R", part_num = 2, total_parts = 4), "tsfae12cpart2of4.rtf") +# }) + +# test_that("tsfae12cpart3of4", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae12c.R", part_num = 3, total_parts = 4), "tsfae12cpart3of4.rtf") +# }) + +# test_that("tsfae12cpart4of4", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae12c.R", part_num = 4, total_parts = 4), "tsfae12cpart4of4.rtf") +# }) diff --git a/tests/testthat/test-tsfae12d.R b/tests/testthat/test-tsfae12d.R new file mode 100644 index 00000000..a43f5e59 --- /dev/null +++ b/tests/testthat/test-tsfae12d.R @@ -0,0 +1,11 @@ +test_that("tsfae12dpart1of2", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae12d.R", part_num = 1, total_parts = 2), "tsfae12dpart1of2.rtf") +}) + +# test_that("tsfae12dpart2of2", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae12d.R", part_num = 2, total_parts = 2), "tsfae12dpart2of2.rtf") +# }) diff --git a/tests/testthat/test-tsfae13.R b/tests/testthat/test-tsfae13.R deleted file mode 100644 index 4ca3ea53..00000000 --- a/tests/testthat/test-tsfae13.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae13", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae13.R"), "tsfae13.rtf") -}) diff --git a/tests/testthat/test-tsfae13a.R b/tests/testthat/test-tsfae13a.R new file mode 100644 index 00000000..7aa99017 --- /dev/null +++ b/tests/testthat/test-tsfae13a.R @@ -0,0 +1,5 @@ +test_that("tsfae13a", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae13a.R"), "tsfae13a.rtf") +}) diff --git a/tests/testthat/test-tsfae13b.R b/tests/testthat/test-tsfae13b.R new file mode 100644 index 00000000..1cfdf6f4 --- /dev/null +++ b/tests/testthat/test-tsfae13b.R @@ -0,0 +1,5 @@ +test_that("tsfae13b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae13b.R"), "tsfae13b.rtf") +}) diff --git a/tests/testthat/test-tsfae13c.R b/tests/testthat/test-tsfae13c.R new file mode 100644 index 00000000..d452246a --- /dev/null +++ b/tests/testthat/test-tsfae13c.R @@ -0,0 +1,5 @@ +test_that("tsfae13c", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae13c.R"), "tsfae13c.rtf") +}) diff --git a/tests/testthat/test-tsfae13d.R b/tests/testthat/test-tsfae13d.R new file mode 100644 index 00000000..d41f71f6 --- /dev/null +++ b/tests/testthat/test-tsfae13d.R @@ -0,0 +1,5 @@ +test_that("tsfae13d", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae13d.R"), "tsfae13d.rtf") +}) diff --git a/tests/testthat/test-tsfae14.R b/tests/testthat/test-tsfae14.R deleted file mode 100644 index 6addc34a..00000000 --- a/tests/testthat/test-tsfae14.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae14", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae14.R"), "tsfae14.rtf") -}) diff --git a/tests/testthat/test-tsfae15.R b/tests/testthat/test-tsfae15.R deleted file mode 100644 index 1c970188..00000000 --- a/tests/testthat/test-tsfae15.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae15", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae15.R"), "tsfae15.rtf") -}) diff --git a/tests/testthat/test-tsfae16part1.R b/tests/testthat/test-tsfae16part1.R deleted file mode 100644 index 09991419..00000000 --- a/tests/testthat/test-tsfae16part1.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae16part1of2", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae16.R", part_num = 1, total_parts = 2), "tsfae16part1of2.rtf") -}) diff --git a/tests/testthat/test-tsfae16part2.R b/tests/testthat/test-tsfae16part2.R deleted file mode 100644 index 44fe36ae..00000000 --- a/tests/testthat/test-tsfae16part2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae16part2of2", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae16.R", part_num = 2, total_parts = 2), "tsfae16part2of2.rtf") -}) diff --git a/tests/testthat/test-tsfae17a.R b/tests/testthat/test-tsfae17a.R deleted file mode 100644 index 1ee4676b..00000000 --- a/tests/testthat/test-tsfae17a.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae17a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae17a.R"), "tsfae17a.rtf") -}) diff --git a/tests/testthat/test-tsfae17b.R b/tests/testthat/test-tsfae17b.R deleted file mode 100644 index bc79dc4c..00000000 --- a/tests/testthat/test-tsfae17b.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae17b", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae17b.R"), "tsfae17b.rtf") -}) diff --git a/tests/testthat/test-tsfae17c.R b/tests/testthat/test-tsfae17c.R deleted file mode 100644 index d4d7ffaf..00000000 --- a/tests/testthat/test-tsfae17c.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae17c", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae17c.R"), "tsfae17c.rtf") -}) diff --git a/tests/testthat/test-tsfae17d.R b/tests/testthat/test-tsfae17d.R deleted file mode 100644 index 62a9f329..00000000 --- a/tests/testthat/test-tsfae17d.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae17d", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae17d.R"), "tsfae17d.rtf") -}) diff --git a/tests/testthat/test-tsfae18a.R b/tests/testthat/test-tsfae18a.R new file mode 100644 index 00000000..642a53ce --- /dev/null +++ b/tests/testthat/test-tsfae18a.R @@ -0,0 +1,5 @@ +test_that("tsfae18a", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae18a.R"), "tsfae18a.rtf") +}) diff --git a/tests/testthat/test-tsfae18b.R b/tests/testthat/test-tsfae18b.R new file mode 100644 index 00000000..adeafe8d --- /dev/null +++ b/tests/testthat/test-tsfae18b.R @@ -0,0 +1,5 @@ +test_that("tsfae18b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae18b.R"), "tsfae18b.rtf") +}) diff --git a/tests/testthat/test-tsfae18c.R b/tests/testthat/test-tsfae18c.R new file mode 100644 index 00000000..7b8516a1 --- /dev/null +++ b/tests/testthat/test-tsfae18c.R @@ -0,0 +1,5 @@ +test_that("tsfae18c", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae18c.R"), "tsfae18c.rtf") +}) diff --git a/tests/testthat/test-tsfae18d.R b/tests/testthat/test-tsfae18d.R new file mode 100644 index 00000000..93df864b --- /dev/null +++ b/tests/testthat/test-tsfae18d.R @@ -0,0 +1,5 @@ +test_that("tsfae18d", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae18d.R"), "tsfae18d.rtf") +}) diff --git a/tests/testthat/test-tsfae19a.R b/tests/testthat/test-tsfae19a.R deleted file mode 100644 index b74d24d4..00000000 --- a/tests/testthat/test-tsfae19a.R +++ /dev/null @@ -1,7 +0,0 @@ -Sys.setenv(JUNCO_DISABLE_VALIDATION = TRUE) -test_that("tsfae19a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae19a.R"), "tsfae19a.rtf") -}) -Sys.setenv(JUNCO_DISABLE_VALIDATION = FALSE) diff --git a/tests/testthat/test-tsfae19b.R b/tests/testthat/test-tsfae19b.R deleted file mode 100644 index 60dacb4a..00000000 --- a/tests/testthat/test-tsfae19b.R +++ /dev/null @@ -1,7 +0,0 @@ -Sys.setenv(JUNCO_DISABLE_VALIDATION = TRUE) -test_that("tsfae19b", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae19b.R"), "tsfae19b.rtf") -}) -Sys.setenv(JUNCO_DISABLE_VALIDATION = FALSE) diff --git a/tests/testthat/test-tsfae19c.R b/tests/testthat/test-tsfae19c.R deleted file mode 100644 index 4ac5faaa..00000000 --- a/tests/testthat/test-tsfae19c.R +++ /dev/null @@ -1,7 +0,0 @@ -Sys.setenv(JUNCO_DISABLE_VALIDATION = TRUE) -test_that("tsfae19c", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae19c.R"), "tsfae19c.rtf") -}) -Sys.setenv(JUNCO_DISABLE_VALIDATION = FALSE) diff --git a/tests/testthat/test-tsfae19d.R b/tests/testthat/test-tsfae19d.R deleted file mode 100644 index 31588074..00000000 --- a/tests/testthat/test-tsfae19d.R +++ /dev/null @@ -1,7 +0,0 @@ -Sys.setenv(JUNCO_DISABLE_VALIDATION = TRUE) -test_that("tsfae19d", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae19d.R"), "tsfae19d.rtf") -}) -Sys.setenv(JUNCO_DISABLE_VALIDATION = FALSE) diff --git a/tests/testthat/test-tsfae20c.R b/tests/testthat/test-tsfae20c.R index d54e7f18..146f5f4d 100644 --- a/tests/testthat/test-tsfae20c.R +++ b/tests/testthat/test-tsfae20c.R @@ -1,5 +1,11 @@ -test_that("tsfae20c", { +test_that("tsfae20cpart1of2", { skip_if_not_installed("envsetup") - expect_snapshot_file(write_test_rtf_for("tsfae20c.R"), "tsfae20c.rtf") + expect_snapshot_file(write_test_rtf_for("tsfae20c.R", part_num = 1, total_parts = 2), "tsfae20cpart1of2.rtf") }) + +# test_that("tsfae20cpart2of2", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae20c.R", part_num = 2, total_parts = 2), "tsfae20cpart2of2.rtf") +# }) diff --git a/tests/testthat/test-tsfae20d.R b/tests/testthat/test-tsfae20d.R new file mode 100644 index 00000000..63ba933d --- /dev/null +++ b/tests/testthat/test-tsfae20d.R @@ -0,0 +1,17 @@ +test_that("tsfae20dpart1of3", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfae20d.R", part_num = 1, total_parts = 3), "tsfae20dpart1of3.rtf") +}) + +# test_that("tsfae20dpart2of3", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae20d.R", part_num = 2, total_parts = 3), "tsfae20dpart2of3.rtf") +# }) + +# test_that("tsfae20dpart3of3", { +# skip_if_not_installed("envsetup") + +# expect_snapshot_file(write_test_rtf_for("tsfae20d.R", part_num = 3, total_parts = 3), "tsfae20dpart3of3.rtf") +# }) diff --git a/tests/testthat/test-tsfae21apart1.R b/tests/testthat/test-tsfae21apart1.R deleted file mode 100644 index 99347915..00000000 --- a/tests/testthat/test-tsfae21apart1.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae21apart1of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae21a.R", part_num = 1, total_parts = 4), "tsfae21apart1of4.rtf") -}) diff --git a/tests/testthat/test-tsfae21apart2.R b/tests/testthat/test-tsfae21apart2.R deleted file mode 100644 index fb20216c..00000000 --- a/tests/testthat/test-tsfae21apart2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae21apart2of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae21a.R", part_num = 2, total_parts = 4), "tsfae21apart2of4.rtf") -}) diff --git a/tests/testthat/test-tsfae21apart3.R b/tests/testthat/test-tsfae21apart3.R deleted file mode 100644 index c464966b..00000000 --- a/tests/testthat/test-tsfae21apart3.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae21apart3of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae21a.R", part_num = 3, total_parts = 4), "tsfae21apart3of4.rtf") -}) diff --git a/tests/testthat/test-tsfae21apart4.R b/tests/testthat/test-tsfae21apart4.R deleted file mode 100644 index 46c9ea93..00000000 --- a/tests/testthat/test-tsfae21apart4.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae21apart4of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae21a.R", part_num = 4, total_parts = 4), "tsfae21apart4of4.rtf") -}) diff --git a/tests/testthat/test-tsfae21bpart1.R b/tests/testthat/test-tsfae21bpart1.R deleted file mode 100644 index 67b230ae..00000000 --- a/tests/testthat/test-tsfae21bpart1.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae21bpart1of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae21b.R", part_num = 1, total_parts = 4), "tsfae21bpart1of4.rtf") -}) diff --git a/tests/testthat/test-tsfae21bpart2.R b/tests/testthat/test-tsfae21bpart2.R deleted file mode 100644 index 1ea57f99..00000000 --- a/tests/testthat/test-tsfae21bpart2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae21bpart2of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae21b.R", part_num = 2, total_parts = 4), "tsfae21bpart2of4.rtf") -}) diff --git a/tests/testthat/test-tsfae21bpart3.R b/tests/testthat/test-tsfae21bpart3.R deleted file mode 100644 index 820b2b65..00000000 --- a/tests/testthat/test-tsfae21bpart3.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae21bpart3of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae21b.R", part_num = 3, total_parts = 4), "tsfae21bpart3of4.rtf") -}) diff --git a/tests/testthat/test-tsfae21bpart4.R b/tests/testthat/test-tsfae21bpart4.R deleted file mode 100644 index cb1a814a..00000000 --- a/tests/testthat/test-tsfae21bpart4.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae21bpart4of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae21b.R", part_num = 4, total_parts = 4), "tsfae21bpart4of4.rtf") -}) diff --git a/tests/testthat/test-tsfae21c.R b/tests/testthat/test-tsfae21c.R deleted file mode 100644 index 9328440e..00000000 --- a/tests/testthat/test-tsfae21c.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae21c", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae21c.R"), "tsfae21c.rtf") -}) diff --git a/tests/testthat/test-tsfae21d.R b/tests/testthat/test-tsfae21d.R deleted file mode 100644 index 39f3942f..00000000 --- a/tests/testthat/test-tsfae21d.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae21d", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae21d.R"), "tsfae21d.rtf") -}) diff --git a/tests/testthat/test-tsfae22apart1.R b/tests/testthat/test-tsfae22apart1.R deleted file mode 100644 index dce18812..00000000 --- a/tests/testthat/test-tsfae22apart1.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae22apart1of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae22a.R", part_num = 1, total_parts = 4), "tsfae22apart1of4.rtf") -}) diff --git a/tests/testthat/test-tsfae22apart2.R b/tests/testthat/test-tsfae22apart2.R deleted file mode 100644 index 970d758f..00000000 --- a/tests/testthat/test-tsfae22apart2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae22apart2of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae22a.R", part_num = 2, total_parts = 4), "tsfae22apart2of4.rtf") -}) diff --git a/tests/testthat/test-tsfae22apart3.R b/tests/testthat/test-tsfae22apart3.R deleted file mode 100644 index 009db3de..00000000 --- a/tests/testthat/test-tsfae22apart3.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae22apart3of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae22a.R", part_num = 3, total_parts = 4), "tsfae22apart3of4.rtf") -}) diff --git a/tests/testthat/test-tsfae22apart4.R b/tests/testthat/test-tsfae22apart4.R deleted file mode 100644 index 1082a64d..00000000 --- a/tests/testthat/test-tsfae22apart4.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae22apart4of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae22a.R", part_num = 4, total_parts = 4), "tsfae22apart4of4.rtf") -}) diff --git a/tests/testthat/test-tsfae22bpart1.R b/tests/testthat/test-tsfae22bpart1.R deleted file mode 100644 index eba3d01c..00000000 --- a/tests/testthat/test-tsfae22bpart1.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae22bpart1of2", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae22b.R", part_num = 1, total_parts = 2), "tsfae22bpart1of2.rtf") -}) diff --git a/tests/testthat/test-tsfae22bpart2.R b/tests/testthat/test-tsfae22bpart2.R deleted file mode 100644 index b9edbe38..00000000 --- a/tests/testthat/test-tsfae22bpart2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae22bpart2of2", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae22b.R", part_num = 2, total_parts = 2), "tsfae22bpart2of2.rtf") -}) diff --git a/tests/testthat/test-tsfae22cpart1.R b/tests/testthat/test-tsfae22cpart1.R deleted file mode 100644 index 0688fa85..00000000 --- a/tests/testthat/test-tsfae22cpart1.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae22cpart1of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae22c.R", part_num = 1, total_parts = 4), "tsfae22cpart1of4.rtf") -}) diff --git a/tests/testthat/test-tsfae22cpart2.R b/tests/testthat/test-tsfae22cpart2.R deleted file mode 100644 index 4680955c..00000000 --- a/tests/testthat/test-tsfae22cpart2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae22cpart2of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae22c.R", part_num = 2, total_parts = 4), "tsfae22cpart2of4.rtf") -}) diff --git a/tests/testthat/test-tsfae22cpart3.R b/tests/testthat/test-tsfae22cpart3.R deleted file mode 100644 index c48c400c..00000000 --- a/tests/testthat/test-tsfae22cpart3.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae22cpart3of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae22c.R", part_num = 3, total_parts = 4), "tsfae22cpart3of4.rtf") -}) diff --git a/tests/testthat/test-tsfae22cpart4.R b/tests/testthat/test-tsfae22cpart4.R deleted file mode 100644 index 9b4901c5..00000000 --- a/tests/testthat/test-tsfae22cpart4.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae22cpart4of4", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae22c.R", part_num = 4, total_parts = 4), "tsfae22cpart4of4.rtf") -}) diff --git a/tests/testthat/test-tsfae23a.R b/tests/testthat/test-tsfae23a.R deleted file mode 100644 index 2211c42d..00000000 --- a/tests/testthat/test-tsfae23a.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae23a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae23a.R"), "tsfae23a.rtf") -}) diff --git a/tests/testthat/test-tsfae23b.R b/tests/testthat/test-tsfae23b.R deleted file mode 100644 index 54ae4713..00000000 --- a/tests/testthat/test-tsfae23b.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae23b", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae23b.R"), "tsfae23b.rtf") -}) diff --git a/tests/testthat/test-tsfae23c.R b/tests/testthat/test-tsfae23c.R deleted file mode 100644 index ea0a8fba..00000000 --- a/tests/testthat/test-tsfae23c.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae23c", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae23c.R"), "tsfae23c.rtf") -}) diff --git a/tests/testthat/test-tsfae23d.R b/tests/testthat/test-tsfae23d.R deleted file mode 100644 index f4e9b443..00000000 --- a/tests/testthat/test-tsfae23d.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae23d", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae23d.R"), "tsfae23d.rtf") -}) diff --git a/tests/testthat/test-tsfae24a.R b/tests/testthat/test-tsfae24a.R deleted file mode 100644 index 56ad9b30..00000000 --- a/tests/testthat/test-tsfae24a.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae24a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae24a.R"), "tsfae24a.rtf") -}) diff --git a/tests/testthat/test-tsfae24b.R b/tests/testthat/test-tsfae24b.R deleted file mode 100644 index 3f6b7d32..00000000 --- a/tests/testthat/test-tsfae24b.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae24b", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae24b.R"), "tsfae24b.rtf") -}) diff --git a/tests/testthat/test-tsfae24c.R b/tests/testthat/test-tsfae24c.R deleted file mode 100644 index ea6a1f22..00000000 --- a/tests/testthat/test-tsfae24c.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae24c", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae24c.R"), "tsfae24c.rtf") -}) diff --git a/tests/testthat/test-tsfae24d.R b/tests/testthat/test-tsfae24d.R deleted file mode 100644 index a8adbd81..00000000 --- a/tests/testthat/test-tsfae24d.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae24d", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae24d.R"), "tsfae24d.rtf") -}) diff --git a/tests/testthat/test-tsfae24fpart1.R b/tests/testthat/test-tsfae24fpart1.R deleted file mode 100644 index a9e3ae6a..00000000 --- a/tests/testthat/test-tsfae24fpart1.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae24fpart1of3", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae24f.R", part_num = 1, total_parts = 3), "tsfae24fpart1of3.rtf") -}) diff --git a/tests/testthat/test-tsfae24fpart2.R b/tests/testthat/test-tsfae24fpart2.R deleted file mode 100644 index 92f8c260..00000000 --- a/tests/testthat/test-tsfae24fpart2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae24fpart2of3", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae24f.R", part_num = 2, total_parts = 3), "tsfae24fpart2of3.rtf") -}) diff --git a/tests/testthat/test-tsfae24fpart3.R b/tests/testthat/test-tsfae24fpart3.R deleted file mode 100644 index dd2ab1cd..00000000 --- a/tests/testthat/test-tsfae24fpart3.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfae24fpart3of3", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfae24f.R", part_num = 3, total_parts = 3), "tsfae24fpart3of3.rtf") -}) diff --git a/tests/testthat/test-tsfecg01.R b/tests/testthat/test-tsfecg01.R new file mode 100644 index 00000000..6e648a71 --- /dev/null +++ b/tests/testthat/test-tsfecg01.R @@ -0,0 +1,5 @@ +test_that("tsfecg01", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfecg01.R"), "tsfecg01.rtf") +}) diff --git a/tests/testthat/test-tsfecg01apart1.R b/tests/testthat/test-tsfecg01a.R similarity index 100% rename from tests/testthat/test-tsfecg01apart1.R rename to tests/testthat/test-tsfecg01a.R diff --git a/tests/testthat/test-tsfecg01apart2.R b/tests/testthat/test-tsfecg01apart2.R deleted file mode 100644 index bdd7ef44..00000000 --- a/tests/testthat/test-tsfecg01apart2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfecg01a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfecg01a.R", part_num = 2, total_parts = 3), "tsfecg01apart2of3.rtf") -}) diff --git a/tests/testthat/test-tsfecg01apart3.R b/tests/testthat/test-tsfecg01apart3.R deleted file mode 100644 index fed75f53..00000000 --- a/tests/testthat/test-tsfecg01apart3.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfecg01a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfecg01a.R", part_num = 3, total_parts = 3), "tsfecg01apart3of3.rtf") -}) diff --git a/tests/testthat/test-tsfecg01part1.R b/tests/testthat/test-tsfecg01part1.R deleted file mode 100644 index e3843622..00000000 --- a/tests/testthat/test-tsfecg01part1.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfecg01", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfecg01.R", part_num = 1, total_parts = 2), "tsfecg01part1of2.rtf") -}) diff --git a/tests/testthat/test-tsfecg01part2.R b/tests/testthat/test-tsfecg01part2.R deleted file mode 100644 index ac400ed9..00000000 --- a/tests/testthat/test-tsfecg01part2.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfecg01", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfecg01.R", part_num = 2, total_parts = 2), "tsfecg01part2of2.rtf") -}) diff --git a/tests/testthat/test-tsfecg06.R b/tests/testthat/test-tsfecg06.R new file mode 100644 index 00000000..ad011418 --- /dev/null +++ b/tests/testthat/test-tsfecg06.R @@ -0,0 +1,5 @@ +test_that("tsfecg06", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfecg06.R"), "tsfecg06.rtf") +}) diff --git a/tests/testthat/test-tsflab01apart1.R b/tests/testthat/test-tsflab01apart1.R deleted file mode 100644 index f541d987..00000000 --- a/tests/testthat/test-tsflab01apart1.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsflab01a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsflab01a.R", part_num = 1, total_parts = 3), - "tsflab01apart1of3.rtf" - ) -}) diff --git a/tests/testthat/test-tsflab01apart2.R b/tests/testthat/test-tsflab01apart2.R deleted file mode 100644 index 2251d94b..00000000 --- a/tests/testthat/test-tsflab01apart2.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsflab01a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsflab01a.R", part_num = 2, total_parts = 3), - "tsflab01apart2of3.rtf" - ) -}) diff --git a/tests/testthat/test-tsflab01apart3.R b/tests/testthat/test-tsflab01apart3.R deleted file mode 100644 index 710ef8d0..00000000 --- a/tests/testthat/test-tsflab01apart3.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsflab01a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsflab01a.R", part_num = 3, total_parts = 3), - "tsflab01apart3of3.rtf" - ) -}) diff --git a/tests/testthat/test-tsflab01b.R b/tests/testthat/test-tsflab01b.R new file mode 100644 index 00000000..2fc7d27c --- /dev/null +++ b/tests/testthat/test-tsflab01b.R @@ -0,0 +1,5 @@ +test_that("tsflab01b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsflab01b.R", rtf_name = "tsflab01b.rtf"), "tsflab01b.rtf") +}) diff --git a/tests/testthat/test-tsflab01part1.R b/tests/testthat/test-tsflab01part1.R deleted file mode 100644 index c6e420d4..00000000 --- a/tests/testthat/test-tsflab01part1.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsflab01", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsflab01.R", part_num = 1, total_parts = 2), - "tsflab01part1of2.rtf" - ) -}) diff --git a/tests/testthat/test-tsflab01part2.R b/tests/testthat/test-tsflab01part2.R deleted file mode 100644 index b01d159d..00000000 --- a/tests/testthat/test-tsflab01part2.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsflab01", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsflab01.R", part_num = 2, total_parts = 2), - "tsflab01part2of2.rtf" - ) -}) diff --git a/tests/testthat/test-tsflab02a.R b/tests/testthat/test-tsflab02a.R deleted file mode 100644 index 7e6501d2..00000000 --- a/tests/testthat/test-tsflab02a.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsflab02a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsflab02a.R"), "tsflab02a.rtf") -}) diff --git a/tests/testthat/test-tsflab02b.R b/tests/testthat/test-tsflab02b.R index 3cef00f4..54a3d5f6 100644 --- a/tests/testthat/test-tsflab02b.R +++ b/tests/testthat/test-tsflab02b.R @@ -1,5 +1,5 @@ test_that("tsflab02b", { skip_if_not_installed("envsetup") - expect_snapshot_file(write_test_rtf_for("tsflab02b.R"), "tsflab02b.rtf") + expect_snapshot_file(write_test_rtf_for("tsflab02b.R", rtf_name = "tsflab02b.rtf"), "tsflab02b.rtf") }) diff --git a/tests/testthat/test-tsflab02c.R b/tests/testthat/test-tsflab02c.R new file mode 100644 index 00000000..75634d95 --- /dev/null +++ b/tests/testthat/test-tsflab02c.R @@ -0,0 +1,5 @@ +test_that("tsflab02c", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsflab02c.R", rtf_name = "tsflab02c.rtf"), "tsflab02c.rtf") +}) diff --git a/tests/testthat/test-tsflab03a.R b/tests/testthat/test-tsflab03a.R deleted file mode 100644 index b55e3991..00000000 --- a/tests/testthat/test-tsflab03a.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsflab03a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsflab03a.R"), "tsflab03a.rtf") -}) diff --git a/tests/testthat/test-tsflab04a.R b/tests/testthat/test-tsflab04a.R index 6091cad4..2c8ca7fb 100644 --- a/tests/testthat/test-tsflab04a.R +++ b/tests/testthat/test-tsflab04a.R @@ -1,5 +1,5 @@ test_that("tsflab04a", { skip_if_not_installed("envsetup") - expect_snapshot_file(write_test_rtf_for("tsflab04a.R"), "tsflab04a.rtf") + expect_snapshot_file(write_test_rtf_for("tsflab04a.R", rtf_name = "tsflab04a.rtf"), "tsflab04a.rtf") }) diff --git a/tests/testthat/test-tsflab04b.R b/tests/testthat/test-tsflab04b.R index 604a467b..e7b74762 100644 --- a/tests/testthat/test-tsflab04b.R +++ b/tests/testthat/test-tsflab04b.R @@ -1,5 +1,5 @@ test_that("tsflab04b", { skip_if_not_installed("envsetup") - expect_snapshot_file(write_test_rtf_for("tsflab04b.R"), "tsflab04b.rtf") + expect_snapshot_file(write_test_rtf_for("tsflab04b.R", rtf_name = "tsflab04b.rtf"), "tsflab04b.rtf") }) diff --git a/tests/testthat/test-tsflab08.R b/tests/testthat/test-tsflab08.R new file mode 100644 index 00000000..68aa118e --- /dev/null +++ b/tests/testthat/test-tsflab08.R @@ -0,0 +1,5 @@ +test_that("tsflab08", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsflab08.R"), "tsflab08.rtf") +}) diff --git a/tests/testthat/test-tsflab09.R b/tests/testthat/test-tsflab09.R new file mode 100644 index 00000000..3948adad --- /dev/null +++ b/tests/testthat/test-tsflab09.R @@ -0,0 +1,5 @@ +test_that("tsflab09", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsflab09.R"), "tsflab09.rtf") +}) diff --git a/tests/testthat/test-tsflab10.R b/tests/testthat/test-tsflab10.R new file mode 100644 index 00000000..233317a7 --- /dev/null +++ b/tests/testthat/test-tsflab10.R @@ -0,0 +1,5 @@ +test_that("tsflab10", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsflab10.R"), "tsflab10.rtf") +}) diff --git a/tests/testthat/test-tsfvit01.R b/tests/testthat/test-tsfvit01.R new file mode 100644 index 00000000..2b157397 --- /dev/null +++ b/tests/testthat/test-tsfvit01.R @@ -0,0 +1,5 @@ +test_that("tsfvit01", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsfvit01.R"), "tsfvit01.rtf") +}) diff --git a/tests/testthat/test-tsfvit01apart1.R b/tests/testthat/test-tsfvit01apart1.R deleted file mode 100644 index 12adffc4..00000000 --- a/tests/testthat/test-tsfvit01apart1.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsfvit01a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsfvit01a.R", part_num = 1, total_parts = 4), - "tsfvit01apart1of4.rtf" - ) -}) diff --git a/tests/testthat/test-tsfvit01apart2.R b/tests/testthat/test-tsfvit01apart2.R deleted file mode 100644 index c5707403..00000000 --- a/tests/testthat/test-tsfvit01apart2.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsfvit01a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsfvit01a.R", part_num = 2, total_parts = 4), - "tsfvit01apart2of4.rtf" - ) -}) diff --git a/tests/testthat/test-tsfvit01apart3.R b/tests/testthat/test-tsfvit01apart3.R deleted file mode 100644 index 7ed8578a..00000000 --- a/tests/testthat/test-tsfvit01apart3.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsfvit01a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsfvit01a.R", part_num = 3, total_parts = 4), - "tsfvit01apart3of4.rtf" - ) -}) diff --git a/tests/testthat/test-tsfvit01apart4.R b/tests/testthat/test-tsfvit01apart4.R deleted file mode 100644 index e3083a8d..00000000 --- a/tests/testthat/test-tsfvit01apart4.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsfvit01a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsfvit01a.R", part_num = 4, total_parts = 4), - "tsfvit01apart4of4.rtf" - ) -}) diff --git a/tests/testthat/test-tsfvit01part1.R b/tests/testthat/test-tsfvit01part1.R deleted file mode 100644 index 6aaf3b23..00000000 --- a/tests/testthat/test-tsfvit01part1.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsfvit01", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsfvit01.R", part_num = 1, total_parts = 4), - "tsfvit01part1of4.rtf" - ) -}) diff --git a/tests/testthat/test-tsfvit01part2.R b/tests/testthat/test-tsfvit01part2.R deleted file mode 100644 index 952ee042..00000000 --- a/tests/testthat/test-tsfvit01part2.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsfvit01", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsfvit01.R", part_num = 2, total_parts = 4), - "tsfvit01part2of4.rtf" - ) -}) diff --git a/tests/testthat/test-tsfvit01part3.R b/tests/testthat/test-tsfvit01part3.R deleted file mode 100644 index 3521842c..00000000 --- a/tests/testthat/test-tsfvit01part3.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsfvit01", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsfvit01.R", part_num = 3, total_parts = 4), - "tsfvit01part3of4.rtf" - ) -}) diff --git a/tests/testthat/test-tsfvit01part4.R b/tests/testthat/test-tsfvit01part4.R deleted file mode 100644 index 2e64eff5..00000000 --- a/tests/testthat/test-tsfvit01part4.R +++ /dev/null @@ -1,8 +0,0 @@ -test_that("tsfvit01", { - skip_if_not_installed("envsetup") - - expect_snapshot_file( - write_test_rtf_for("tsfvit01.R", part_num = 4, total_parts = 4), - "tsfvit01part4of4.rtf" - ) -}) diff --git a/tests/testthat/test-tsfvit05.R b/tests/testthat/test-tsfvit05.R deleted file mode 100644 index baf0d788..00000000 --- a/tests/testthat/test-tsfvit05.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfvit05", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfvit05.R"), "tsfvit05.rtf") -}) diff --git a/tests/testthat/test-tsfvit06.R b/tests/testthat/test-tsfvit06.R deleted file mode 100644 index 61383898..00000000 --- a/tests/testthat/test-tsfvit06.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsfvit06", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsfvit06.R"), "tsfvit06.rtf") -}) diff --git a/tests/testthat/test-tsidem03.R b/tests/testthat/test-tsidem03.R new file mode 100644 index 00000000..857e7253 --- /dev/null +++ b/tests/testthat/test-tsidem03.R @@ -0,0 +1,5 @@ +test_that("tsidem03", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsidem03.R"), "tsidem03.rtf") +}) diff --git a/tests/testthat/test-tsidev01.R b/tests/testthat/test-tsidev01.R new file mode 100644 index 00000000..532e6b10 --- /dev/null +++ b/tests/testthat/test-tsidev01.R @@ -0,0 +1,5 @@ +test_that("tsidev01", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsidev01.R"), "tsidev01.rtf") +}) diff --git a/tests/testthat/test-tsidev02.R b/tests/testthat/test-tsidev02.R new file mode 100644 index 00000000..3e919c5f --- /dev/null +++ b/tests/testthat/test-tsidev02.R @@ -0,0 +1,5 @@ +test_that("tsidev02", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsidev02.R"), "tsidev02.rtf") +}) diff --git a/tests/testthat/test-tsids02a.R b/tests/testthat/test-tsids02a.R deleted file mode 100644 index 9823183b..00000000 --- a/tests/testthat/test-tsids02a.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsids02a", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsids02a.R"), "tsids02a.rtf") -}) diff --git a/tests/testthat/test-tsids02b.R b/tests/testthat/test-tsids02b.R new file mode 100644 index 00000000..196d4162 --- /dev/null +++ b/tests/testthat/test-tsids02b.R @@ -0,0 +1,5 @@ +test_that("tsids02b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsids02b.R"), "tsids02b.rtf") +}) diff --git a/tests/testthat/test-tsiex02b.R b/tests/testthat/test-tsiex02b.R new file mode 100644 index 00000000..05723107 --- /dev/null +++ b/tests/testthat/test-tsiex02b.R @@ -0,0 +1,5 @@ +test_that("tsiex02b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsiex02b.R"), "tsiex02b.rtf") +}) diff --git a/tests/testthat/test-tsiex03b.R b/tests/testthat/test-tsiex03b.R new file mode 100644 index 00000000..05d4c02f --- /dev/null +++ b/tests/testthat/test-tsiex03b.R @@ -0,0 +1,5 @@ +test_that("tsiex03b", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsiex03b.R"), "tsiex03b.rtf") +}) diff --git a/tests/testthat/test-tsiex04.R b/tests/testthat/test-tsiex04.R deleted file mode 100644 index f6199f32..00000000 --- a/tests/testthat/test-tsiex04.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsiex04", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsiex04.R"), "tsiex04.rtf") -}) diff --git a/tests/testthat/test-tsiex05.R b/tests/testthat/test-tsiex05.R new file mode 100644 index 00000000..d926f904 --- /dev/null +++ b/tests/testthat/test-tsiex05.R @@ -0,0 +1,5 @@ +test_that("tsiex05", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsiex05.R"), "tsiex05.rtf") +}) diff --git a/tests/testthat/test-tsiex08.R b/tests/testthat/test-tsiex08.R deleted file mode 100644 index 01453be4..00000000 --- a/tests/testthat/test-tsiex08.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsiex08", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsiex08.R"), "tsiex08.rtf") -}) diff --git a/tests/testthat/test-tsiex11.R b/tests/testthat/test-tsiex11.R deleted file mode 100644 index aef900a3..00000000 --- a/tests/testthat/test-tsiex11.R +++ /dev/null @@ -1,5 +0,0 @@ -test_that("tsiex11", { - skip_if_not_installed("envsetup") - - expect_snapshot_file(write_test_rtf_for("tsiex11.R"), "tsiex11.rtf") -}) diff --git a/tests/testthat/test-tsiex12.R b/tests/testthat/test-tsiex12.R new file mode 100644 index 00000000..43d65c2e --- /dev/null +++ b/tests/testthat/test-tsiex12.R @@ -0,0 +1,5 @@ +test_that("tsiex12", { + skip_if_not_installed("envsetup") + + expect_snapshot_file(write_test_rtf_for("tsiex12.R"), "tsiex12.rtf") +}) diff --git a/tests/testthat/tsflab02b.rtf b/tests/testthat/tsflab02b.rtf new file mode 100644 index 00000000..bd5f2a08 --- /dev/null +++ b/tests/testthat/tsflab02b.rtf @@ -0,0 +1,2146 @@ +{\rtf1\ansi\deff0\landscape\paperw15840\paperh12240\margl1440\margr1440\margt1440\margb1440\headery1440\footery1440{\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang9\langfe3081\loch\f0\hich\af0\dbch\af31505\cgrid\langnp9\langfenp3081 \snext0 \sqformat \spriority0 Normal;}{\s15\ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat caption;}{\s16 \ql \fi-1152\li1152\ri0\keepn\widctlpar\tx1152\wrapdefault\faauto\rin0\lin1152\itap0 \rtlch\fcs1 \af0\afs18\alang1025 \ltrch\fcs0 \b\fs20\lang1033\langfe1033\loch\f0\hich\af0\dbch\af31505\cgrid\langnp1033\langfenp1033 \sbasedon0 \snext0 \sqformat;}} + + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6864 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8211 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10456 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs20 \b \pnhang\trhdr\fi-1152\li1152\keepn\s15 TSFLAB02b:\tab Dummy Title\b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\pard\intbl\ql\fs20 \b \b0 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadr67\clpadfr3\cellx2823 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx6864 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx8211 +\clmgf\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx10456 +\clmrg\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\clpadt67\clpadft3\clpadr67\clpadfr3\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr Laboratory Test \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr Active Study Agent \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\pard\intbl\qc\fs18 \keepn\trhdr Risk Difference (%) (95% CI) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li180\fi0 Study Visit \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose \cell +\pard\intbl\qc\fs18 \keepn\trhdr Combined \cell +\pard\intbl\qc\fs18 \keepn\trhdr Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline Low Dose vs Placebo \cell +\pard\intbl\qc\fs18 \keepn\trhdr Xanomeline High Dose vs Placebo \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \keepn\trhdr \intbl\li360\fi0 Threshold Level, n (%) \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=67 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=51 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=118 \cell +\pard\intbl\qc\fs18 \keepn\trhdr N=64 \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\pard\intbl\qc\fs18 \keepn\trhdr \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\brdrs\brdrw18\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, male \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 22 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (125-135 g/L) \cell +\pard\intbl\qc\fs18 6 (28.6%) \cell +\pard\intbl\qc\fs18 4 (18.2%) \cell +\pard\intbl\qc\fs18 10 (23.3%) \cell +\pard\intbl\qc\fs18 3 (17.6%) \cell +\pard\intbl\qc\fs18 10.9 (-15.6, 37.4) \cell +\pard\intbl\qc\fs18 0.5 (-23.7, 24.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 g/L) \cell +\pard\intbl\qc\fs18 3 (14.3%) \cell +\pard\intbl\qc\fs18 6 (27.3%) \cell +\pard\intbl\qc\fs18 9 (20.9%) \cell +\pard\intbl\qc\fs18 4 (23.5%) \cell +\pard\intbl\qc\fs18 -9.2 (-34.4, 15.9) \cell +\pard\intbl\qc\fs18 3.7 (-23.7, 31.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<105 g/L) \cell +\pard\intbl\qc\fs18 7 (33.3%) \cell +\pard\intbl\qc\fs18 7 (31.8%) \cell +\pard\intbl\qc\fs18 14 (32.6%) \cell +\pard\intbl\qc\fs18 6 (35.3%) \cell +\pard\intbl\qc\fs18 -2.0 (-32.3, 28.4) \cell +\pard\intbl\qc\fs18 -3.5 (-33.4, 26.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 13 \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 20 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (125-135 g/L) \cell +\pard\intbl\qc\fs18 4 (30.8%) \cell +\pard\intbl\qc\fs18 4 (19.0%) \cell +\pard\intbl\qc\fs18 8 (23.5%) \cell +\pard\intbl\qc\fs18 4 (20.0%) \cell +\pard\intbl\qc\fs18 10.8 (-19.8, 41.4) \cell +\pard\intbl\qc\fs18 -1.0 (-25.2, 23.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 g/L) \cell +\pard\intbl\qc\fs18 3 (23.1%) \cell +\pard\intbl\qc\fs18 8 (38.1%) \cell +\pard\intbl\qc\fs18 11 (32.4%) \cell +\pard\intbl\qc\fs18 9 (45.0%) \cell +\pard\intbl\qc\fs18 -21.9 (-53.5, 9.7) \cell +\pard\intbl\qc\fs18 -6.9 (-37.0, 23.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<105 g/L) \cell +\pard\intbl\qc\fs18 4 (30.8%) \cell +\pard\intbl\qc\fs18 6 (28.6%) \cell +\pard\intbl\qc\fs18 10 (29.4%) \cell +\pard\intbl\qc\fs18 6 (30.0%) \cell +\pard\intbl\qc\fs18 0.8 (-31.4, 32.9) \cell +\pard\intbl\qc\fs18 -1.4 (-29.3, 26.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 11 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 15 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (125-135 g/L) \cell +\pard\intbl\qc\fs18 1 (9.1%) \cell +\pard\intbl\qc\fs18 4 (17.4%) \cell +\pard\intbl\qc\fs18 5 (14.7%) \cell +\pard\intbl\qc\fs18 3 (20.0%) \cell +\pard\intbl\qc\fs18 -10.9 (-37.3, 15.5) \cell +\pard\intbl\qc\fs18 -2.6 (-28.1, 22.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 g/L) \cell +\pard\intbl\qc\fs18 4 (36.4%) \cell +\pard\intbl\qc\fs18 6 (26.1%) \cell +\pard\intbl\qc\fs18 10 (29.4%) \cell +\pard\intbl\qc\fs18 6 (40.0%) \cell +\pard\intbl\qc\fs18 -3.6 (-41.4, 34.1) \cell +\pard\intbl\qc\fs18 -13.9 (-44.5, 16.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<105 g/L) \cell +\pard\intbl\qc\fs18 2 (18.2%) \cell +\pard\intbl\qc\fs18 7 (30.4%) \cell +\pard\intbl\qc\fs18 9 (26.5%) \cell +\pard\intbl\qc\fs18 3 (20.0%) \cell +\pard\intbl\qc\fs18 -1.8 (-32.3, 28.7) \cell +\pard\intbl\qc\fs18 10.4 (-17.2, 38.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Hemoglobin, female \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 19 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 30 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (110-120 g/L) \cell +\pard\intbl\qc\fs18 7 (23.3%) \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 10 (20.4%) \cell +\pard\intbl\qc\fs18 12 (40.0%) \cell +\pard\intbl\qc\fs18 -16.7 (-39.8, 6.5) \cell +\pard\intbl\qc\fs18 -24.2 (-48.2, -0.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<110 g/L) \cell +\pard\intbl\qc\fs18 12 (40.0%) \cell +\pard\intbl\qc\fs18 8 (42.1%) \cell +\pard\intbl\qc\fs18 20 (40.8%) \cell +\pard\intbl\qc\fs18 6 (20.0%) \cell +\pard\intbl\qc\fs18 20.0 (-2.6, 42.6) \cell +\pard\intbl\qc\fs18 22.1 (-4.3, 48.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<95 g/L) \cell +\pard\intbl\qc\fs18 5 (16.7%) \cell +\pard\intbl\qc\fs18 3 (15.8%) \cell +\pard\intbl\qc\fs18 8 (16.3%) \cell +\pard\intbl\qc\fs18 6 (20.0%) \cell +\pard\intbl\qc\fs18 -3.3 (-22.9, 16.2) \cell +\pard\intbl\qc\fs18 -4.2 (-26.0, 17.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 23 \cell +\pard\intbl\qc\fs18 17 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 27 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (110-120 g/L) \cell +\pard\intbl\qc\fs18 7 (30.4%) \cell +\pard\intbl\qc\fs18 4 (23.5%) \cell +\pard\intbl\qc\fs18 11 (27.5%) \cell +\pard\intbl\qc\fs18 5 (18.5%) \cell +\pard\intbl\qc\fs18 11.9 (-11.9, 35.8) \cell +\pard\intbl\qc\fs18 5.0 (-19.9, 29.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<110 g/L) \cell +\pard\intbl\qc\fs18 6 (26.1%) \cell +\pard\intbl\qc\fs18 5 (29.4%) \cell +\pard\intbl\qc\fs18 11 (27.5%) \cell +\pard\intbl\qc\fs18 6 (22.2%) \cell +\pard\intbl\qc\fs18 3.9 (-20.0, 27.7) \cell +\pard\intbl\qc\fs18 7.2 (-19.6, 33.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<95 g/L) \cell +\pard\intbl\qc\fs18 6 (26.1%) \cell +\pard\intbl\qc\fs18 5 (29.4%) \cell +\pard\intbl\qc\fs18 11 (27.5%) \cell +\pard\intbl\qc\fs18 8 (29.6%) \cell +\pard\intbl\qc\fs18 -3.5 (-28.4, 21.3) \cell +\pard\intbl\qc\fs18 -0.2 (-27.9, 27.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 21 \cell +\pard\intbl\qc\fs18 16 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 24 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (110-120 g/L) \cell +\pard\intbl\qc\fs18 2 (9.5%) \cell +\pard\intbl\qc\fs18 1 (6.3%) \cell +\pard\intbl\qc\fs18 3 (8.1%) \cell +\pard\intbl\qc\fs18 6 (25.0%) \cell +\pard\intbl\qc\fs18 -15.5 (-36.9, 5.9) \cell +\pard\intbl\qc\fs18 -18.8 (-39.7, 2.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<110 g/L) \cell +\pard\intbl\qc\fs18 10 (47.6%) \cell +\pard\intbl\qc\fs18 7 (43.8%) \cell +\pard\intbl\qc\fs18 17 (45.9%) \cell +\pard\intbl\qc\fs18 6 (25.0%) \cell +\pard\intbl\qc\fs18 22.6 (-4.9, 50.1) \cell +\pard\intbl\qc\fs18 18.8 (-11.1, 48.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<95 g/L) \cell +\pard\intbl\qc\fs18 2 (9.5%) \cell +\pard\intbl\qc\fs18 4 (25.0%) \cell +\pard\intbl\qc\fs18 6 (16.2%) \cell +\pard\intbl\qc\fs18 4 (16.7%) \cell +\pard\intbl\qc\fs18 -7.1 (-26.6, 12.3) \cell +\pard\intbl\qc\fs18 8.3 (-17.6, 34.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, low \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 108 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 90 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<3.5 10^9/L) \cell +\pard\intbl\qc\fs18 10 (20.8%) \cell +\pard\intbl\qc\fs18 9 (21.4%) \cell +\pard\intbl\qc\fs18 19 (21.1%) \cell +\pard\intbl\qc\fs18 14 (27.5%) \cell +\pard\intbl\qc\fs18 -6.6 (-23.4, 10.2) \cell +\pard\intbl\qc\fs18 -6.0 (-23.5, 11.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<3.0 10^9/L) \cell +\pard\intbl\qc\fs18 10 (20.8%) \cell +\pard\intbl\qc\fs18 7 (16.7%) \cell +\pard\intbl\qc\fs18 17 (18.9%) \cell +\pard\intbl\qc\fs18 10 (19.6%) \cell +\pard\intbl\qc\fs18 1.2 (-14.6, 17.1) \cell +\pard\intbl\qc\fs18 -2.9 (-18.6, 12.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 15 (31.3%) \cell +\pard\intbl\qc\fs18 15 (35.7%) \cell +\pard\intbl\qc\fs18 30 (33.3%) \cell +\pard\intbl\qc\fs18 14 (27.5%) \cell +\pard\intbl\qc\fs18 3.8 (-14.1, 21.7) \cell +\pard\intbl\qc\fs18 8.3 (-10.7, 27.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 36 \cell +\pard\intbl\qc\fs18 41 \cell +\pard\intbl\qc\fs18 77 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<3.5 10^9/L) \cell +\pard\intbl\qc\fs18 14 (38.9%) \cell +\pard\intbl\qc\fs18 10 (24.4%) \cell +\pard\intbl\qc\fs18 24 (31.2%) \cell +\pard\intbl\qc\fs18 13 (26.5%) \cell +\pard\intbl\qc\fs18 12.4 (-7.8, 32.5) \cell +\pard\intbl\qc\fs18 -2.1 (-20.2, 15.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<3.0 10^9/L) \cell +\pard\intbl\qc\fs18 8 (22.2%) \cell +\pard\intbl\qc\fs18 16 (39.0%) \cell +\pard\intbl\qc\fs18 24 (31.2%) \cell +\pard\intbl\qc\fs18 10 (20.4%) \cell +\pard\intbl\qc\fs18 1.8 (-15.8, 19.5) \cell +\pard\intbl\qc\fs18 18.6 (-0.1, 37.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 7 (19.4%) \cell +\pard\intbl\qc\fs18 9 (22.0%) \cell +\pard\intbl\qc\fs18 16 (20.8%) \cell +\pard\intbl\qc\fs18 14 (28.6%) \cell +\pard\intbl\qc\fs18 -9.1 (-27.2, 9.0) \cell +\pard\intbl\qc\fs18 -6.6 (-24.5, 11.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 71 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<3.5 10^9/L) \cell +\pard\intbl\qc\fs18 8 (25.8%) \cell +\pard\intbl\qc\fs18 10 (25.0%) \cell +\pard\intbl\qc\fs18 18 (25.4%) \cell +\pard\intbl\qc\fs18 16 (37.2%) \cell +\pard\intbl\qc\fs18 -11.4 (-32.5, 9.7) \cell +\pard\intbl\qc\fs18 -12.2 (-31.9, 7.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<3.0 10^9/L) \cell +\pard\intbl\qc\fs18 4 (12.9%) \cell +\pard\intbl\qc\fs18 12 (30.0%) \cell +\pard\intbl\qc\fs18 16 (22.5%) \cell +\pard\intbl\qc\fs18 8 (18.6%) \cell +\pard\intbl\qc\fs18 -5.7 (-22.3, 10.9) \cell +\pard\intbl\qc\fs18 11.4 (-7.0, 29.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 11 (35.5%) \cell +\pard\intbl\qc\fs18 10 (25.0%) \cell +\pard\intbl\qc\fs18 21 (29.6%) \cell +\pard\intbl\qc\fs18 12 (27.9%) \cell +\pard\intbl\qc\fs18 7.6 (-14.0, 29.1) \cell +\pard\intbl\qc\fs18 -2.9 (-21.9, 16.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Leukocytes, high \cell +\pard\intbl\qc\fs18 58 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 109 \cell +\pard\intbl\qc\fs18 60 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 48 \cell +\pard\intbl\qc\fs18 42 \cell +\pard\intbl\qc\fs18 90 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (>10.8 10^9/L) \cell +\pard\intbl\qc\fs18 9 (18.8%) \cell +\pard\intbl\qc\fs18 10 (23.8%) \cell +\pard\intbl\qc\fs18 19 (21.1%) \cell +\pard\intbl\qc\fs18 8 (16.3%) \cell +\pard\intbl\qc\fs18 2.4 (-12.7, 17.6) \cell +\pard\intbl\qc\fs18 7.5 (-9.0, 24.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (>13.0 10^9/L) \cell +\pard\intbl\qc\fs18 11 (22.9%) \cell +\pard\intbl\qc\fs18 6 (14.3%) \cell +\pard\intbl\qc\fs18 17 (18.9%) \cell +\pard\intbl\qc\fs18 17 (34.7%) \cell +\pard\intbl\qc\fs18 -11.8 (-29.6, 6.1) \cell +\pard\intbl\qc\fs18 -20.4 (-37.4, -3.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (>15.0 10^9/L) \cell +\pard\intbl\qc\fs18 13 (27.1%) \cell +\pard\intbl\qc\fs18 14 (33.3%) \cell +\pard\intbl\qc\fs18 27 (30.0%) \cell +\pard\intbl\qc\fs18 8 (16.3%) \cell +\pard\intbl\qc\fs18 10.8 (-5.5, 27.0) \cell +\pard\intbl\qc\fs18 17.0 (-0.6, 34.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 78 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (>10.8 10^9/L) \cell +\pard\intbl\qc\fs18 10 (28.6%) \cell +\pard\intbl\qc\fs18 9 (20.9%) \cell +\pard\intbl\qc\fs18 19 (24.4%) \cell +\pard\intbl\qc\fs18 11 (25.0%) \cell +\pard\intbl\qc\fs18 3.6 (-16.1, 23.3) \cell +\pard\intbl\qc\fs18 -4.1 (-21.7, 13.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (>13.0 10^9/L) \cell +\pard\intbl\qc\fs18 10 (28.6%) \cell +\pard\intbl\qc\fs18 11 (25.6%) \cell +\pard\intbl\qc\fs18 21 (26.9%) \cell +\pard\intbl\qc\fs18 11 (25.0%) \cell +\pard\intbl\qc\fs18 3.6 (-16.1, 23.3) \cell +\pard\intbl\qc\fs18 0.6 (-17.7, 18.9) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (>15.0 10^9/L) \cell +\pard\intbl\qc\fs18 9 (25.7%) \cell +\pard\intbl\qc\fs18 7 (16.3%) \cell +\pard\intbl\qc\fs18 16 (20.5%) \cell +\pard\intbl\qc\fs18 15 (34.1%) \cell +\pard\intbl\qc\fs18 -8.4 (-28.5, 11.8) \cell +\pard\intbl\qc\fs18 -17.8 (-35.6, 0.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 33 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (>10.8 10^9/L) \cell +\pard\intbl\qc\fs18 6 (18.2%) \cell +\pard\intbl\qc\fs18 9 (27.3%) \cell +\pard\intbl\qc\fs18 15 (22.7%) \cell +\pard\intbl\qc\fs18 5 (11.4%) \cell +\pard\intbl\qc\fs18 6.8 (-9.3, 23.0) \cell +\pard\intbl\qc\fs18 15.9 (-1.9, 33.8) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (>13.0 10^9/L) \cell +\pard\intbl\qc\fs18 11 (33.3%) \cell +\pard\intbl\qc\fs18 9 (27.3%) \cell +\pard\intbl\qc\fs18 20 (30.3%) \cell +\pard\intbl\qc\fs18 18 (40.9%) \cell +\pard\intbl\qc\fs18 -7.6 (-29.2, 14.1) \cell +\pard\intbl\qc\fs18 -13.6 (-34.7, 7.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (>15.0 10^9/L) \cell +\pard\intbl\qc\fs18 6 (18.2%) \cell +\pard\intbl\qc\fs18 8 (24.2%) \cell +\pard\intbl\qc\fs18 14 (21.2%) \cell +\pard\intbl\qc\fs18 12 (27.3%) \cell +\pard\intbl\qc\fs18 -9.1 (-27.7, 9.5) \cell +\pard\intbl\qc\fs18 -3.0 (-22.7, 16.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Platelets, low \cell +\pard\intbl\qc\fs18 59 \cell +\pard\intbl\qc\fs18 51 \cell +\pard\intbl\qc\fs18 110 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 45 \cell +\pard\intbl\qc\fs18 40 \cell +\pard\intbl\qc\fs18 85 \cell +\pard\intbl\qc\fs18 43 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<140 10^9/L) \cell +\pard\intbl\qc\fs18 13 (28.9%) \cell +\pard\intbl\qc\fs18 8 (20.0%) \cell +\pard\intbl\qc\fs18 21 (24.7%) \cell +\pard\intbl\qc\fs18 5 (11.6%) \cell +\pard\intbl\qc\fs18 17.3 (0.9, 33.6) \cell +\pard\intbl\qc\fs18 8.4 (-7.3, 24.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 10^9/L) \cell +\pard\intbl\qc\fs18 7 (15.6%) \cell +\pard\intbl\qc\fs18 10 (25.0%) \cell +\pard\intbl\qc\fs18 17 (20.0%) \cell +\pard\intbl\qc\fs18 7 (16.3%) \cell +\pard\intbl\qc\fs18 -0.7 (-16.0, 14.6) \cell +\pard\intbl\qc\fs18 8.7 (-8.7, 26.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<100 10^9/L) \cell +\pard\intbl\qc\fs18 8 (17.8%) \cell +\pard\intbl\qc\fs18 11 (27.5%) \cell +\pard\intbl\qc\fs18 19 (22.4%) \cell +\pard\intbl\qc\fs18 16 (37.2%) \cell +\pard\intbl\qc\fs18 -19.4 (-37.7, -1.2) \cell +\pard\intbl\qc\fs18 -9.7 (-29.7, 10.3) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 39 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 76 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<140 10^9/L) \cell +\pard\intbl\qc\fs18 11 (28.2%) \cell +\pard\intbl\qc\fs18 7 (18.9%) \cell +\pard\intbl\qc\fs18 18 (23.7%) \cell +\pard\intbl\qc\fs18 15 (30.6%) \cell +\pard\intbl\qc\fs18 -2.4 (-21.5, 16.7) \cell +\pard\intbl\qc\fs18 -11.7 (-29.7, 6.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 10^9/L) \cell +\pard\intbl\qc\fs18 12 (30.8%) \cell +\pard\intbl\qc\fs18 9 (24.3%) \cell +\pard\intbl\qc\fs18 21 (27.6%) \cell +\pard\intbl\qc\fs18 11 (22.4%) \cell +\pard\intbl\qc\fs18 8.3 (-10.3, 26.9) \cell +\pard\intbl\qc\fs18 1.9 (-16.2, 20.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<100 10^9/L) \cell +\pard\intbl\qc\fs18 9 (23.1%) \cell +\pard\intbl\qc\fs18 8 (21.6%) \cell +\pard\intbl\qc\fs18 17 (22.4%) \cell +\pard\intbl\qc\fs18 12 (24.5%) \cell +\pard\intbl\qc\fs18 -1.4 (-19.3, 16.5) \cell +\pard\intbl\qc\fs18 -2.9 (-20.8, 15.0) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 31 \cell +\pard\intbl\qc\fs18 35 \cell +\pard\intbl\qc\fs18 66 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<140 10^9/L) \cell +\pard\intbl\qc\fs18 6 (19.4%) \cell +\pard\intbl\qc\fs18 9 (25.7%) \cell +\pard\intbl\qc\fs18 15 (22.7%) \cell +\pard\intbl\qc\fs18 6 (15.8%) \cell +\pard\intbl\qc\fs18 3.6 (-14.5, 21.7) \cell +\pard\intbl\qc\fs18 9.9 (-8.6, 28.5) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<125 10^9/L) \cell +\pard\intbl\qc\fs18 11 (35.5%) \cell +\pard\intbl\qc\fs18 12 (34.3%) \cell +\pard\intbl\qc\fs18 23 (34.8%) \cell +\pard\intbl\qc\fs18 14 (36.8%) \cell +\pard\intbl\qc\fs18 -1.4 (-24.1, 21.4) \cell +\pard\intbl\qc\fs18 -2.6 (-24.5, 19.4) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<100 10^9/L) \cell +\pard\intbl\qc\fs18 7 (22.6%) \cell +\pard\intbl\qc\fs18 10 (28.6%) \cell +\pard\intbl\qc\fs18 17 (25.8%) \cell +\pard\intbl\qc\fs18 10 (26.3%) \cell +\pard\intbl\qc\fs18 -3.7 (-24.0, 16.6) \cell +\pard\intbl\qc\fs18 2.3 (-18.2, 22.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 Neutrophils, low \cell +\pard\intbl\qc\fs18 57 \cell +\pard\intbl\qc\fs18 49 \cell +\pard\intbl\qc\fs18 106 \cell +\pard\intbl\qc\fs18 62 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 02 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 47 \cell +\pard\intbl\qc\fs18 38 \cell +\pard\intbl\qc\fs18 85 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<2.0 10^9/L) \cell +\pard\intbl\qc\fs18 12 (25.5%) \cell +\pard\intbl\qc\fs18 9 (23.7%) \cell +\pard\intbl\qc\fs18 21 (24.7%) \cell +\pard\intbl\qc\fs18 8 (18.2%) \cell +\pard\intbl\qc\fs18 7.4 (-9.5, 24.2) \cell +\pard\intbl\qc\fs18 5.5 (-12.2, 23.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 15 (31.9%) \cell +\pard\intbl\qc\fs18 11 (28.9%) \cell +\pard\intbl\qc\fs18 26 (30.6%) \cell +\pard\intbl\qc\fs18 23 (52.3%) \cell +\pard\intbl\qc\fs18 -20.4 (-40.2, -0.5) \cell +\pard\intbl\qc\fs18 -23.3 (-44.0, -2.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<0.5 10^9/L) \cell +\pard\intbl\qc\fs18 9 (19.1%) \cell +\pard\intbl\qc\fs18 10 (26.3%) \cell +\pard\intbl\qc\fs18 19 (22.4%) \cell +\pard\intbl\qc\fs18 7 (15.9%) \cell +\pard\intbl\qc\fs18 3.2 (-12.4, 18.8) \cell +\pard\intbl\qc\fs18 10.4 (-7.3, 28.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 03 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 37 \cell +\pard\intbl\qc\fs18 74 \cell +\pard\intbl\qc\fs18 53 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<2.0 10^9/L) \cell +\pard\intbl\qc\fs18 15 (40.5%) \cell +\pard\intbl\qc\fs18 11 (29.7%) \cell +\pard\intbl\qc\fs18 26 (35.1%) \cell +\pard\intbl\qc\fs18 14 (26.4%) \cell +\pard\intbl\qc\fs18 14.1 (-5.7, 33.9) \cell +\pard\intbl\qc\fs18 3.3 (-15.6, 22.2) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 8 (21.6%) \cell +\pard\intbl\qc\fs18 9 (24.3%) \cell +\pard\intbl\qc\fs18 17 (23.0%) \cell +\pard\intbl\qc\fs18 14 (26.4%) \cell +\pard\intbl\qc\fs18 -4.8 (-22.6, 13.0) \cell +\pard\intbl\qc\fs18 -2.1 (-20.3, 16.1) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<0.5 10^9/L) \cell +\pard\intbl\qc\fs18 7 (18.9%) \cell +\pard\intbl\qc\fs18 9 (24.3%) \cell +\pard\intbl\qc\fs18 16 (21.6%) \cell +\pard\intbl\qc\fs18 16 (30.2%) \cell +\pard\intbl\qc\fs18 -11.3 (-28.9, 6.4) \cell +\pard\intbl\qc\fs18 -5.9 (-24.4, 12.7) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li87\fi-87 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li267\fi-87 Cycle 04 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li447\fi-87 N \cell +\pard\intbl\qc\fs18 29 \cell +\pard\intbl\qc\fs18 34 \cell +\pard\intbl\qc\fs18 63 \cell +\pard\intbl\qc\fs18 44 \cell +\pard\intbl\qc\fs18 \cell +\pard\intbl\qc\fs18 \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 1 (<2.0 10^9/L) \cell +\pard\intbl\qc\fs18 4 (13.8%) \cell +\pard\intbl\qc\fs18 12 (35.3%) \cell +\pard\intbl\qc\fs18 16 (25.4%) \cell +\pard\intbl\qc\fs18 14 (31.8%) \cell +\pard\intbl\qc\fs18 -18.0 (-36.7, 0.6) \cell +\pard\intbl\qc\fs18 3.5 (-17.7, 24.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 2 (<1.0 10^9/L) \cell +\pard\intbl\qc\fs18 10 (34.5%) \cell +\pard\intbl\qc\fs18 8 (23.5%) \cell +\pard\intbl\qc\fs18 18 (28.6%) \cell +\pard\intbl\qc\fs18 8 (18.2%) \cell +\pard\intbl\qc\fs18 16.3 (-4.4, 37.0) \cell +\pard\intbl\qc\fs18 5.3 (-12.9, 23.6) \cell +\row +} + +{ +\trowd +\trqc \clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4170 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5517 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6864 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8211 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10456 +\clbrdrt\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \intbl\li627\fi-87 Level 3 (<0.5 10^9/L) \cell +\pard\intbl\qc\fs18 6 (20.7%) \cell +\pard\intbl\qc\fs18 6 (17.6%) \cell +\pard\intbl\qc\fs18 12 (19.0%) \cell +\pard\intbl\qc\fs18 11 (25.0%) \cell +\pard\intbl\qc\fs18 -4.3 (-23.8, 15.2) \cell +\pard\intbl\qc\fs18 -7.4 (-25.5, 10.8) \cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx6864 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx8211 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx10456 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\brdrs\brdrw18\brdrcf1\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs18 \line Dummy Note: On-treatment is defined as treatment-emergent \cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\pard\intbl\qc\line Dummy Note: On-treatment is defined as treatment-emergent\cell +\row +} + +{ +\trowd +\trqc \clmgf\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx2823 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx4170 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx5517 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx6864 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx8211 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx10456 +\clmrg\clbrdrt\brdrs\brdrw18\brdrcf1\clbrdrl\clbrdrb\clbrdrr\clvertalb\cellx12701 \pard\intbl\ql\fs16 \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\pard\intbl\qc \cell +\row +} + +} \ No newline at end of file